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Mammalian Phenotype Ontology Annotations
Query Results - Summary
15821 genotypes with 51703 annotations displayed of selected term and subterms
Searched Term: immune system phenotype
Allelic Composition
(Genetic Background)
Annotated Term Reference
0610040J01Rikem1(IMPC)Ccpcz/0610040J01Rikem1(IMPC)Ccpcz
(C57BL/6NCrl-0610040J01Rikem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
small spleen J:211773
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/0
(C.FVB-1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan)
abnormal CD8-positive, alpha-beta T cell differentiation J:93488
abnormal T cell activation J:93488
decreased CD8-positive, alpha-beta T cell number J:93488
decreased cytotoxic T cell cytolysis J:93488
decreased dendritic cell number J:93488
increased neutrophil cell number J:194800
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/0
(B6.FVB-1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/J)
abnormal NK cell physiology J:96123
abnormal NK T cell physiology J:96123
decreased circulating interferon-gamma level J:96123
decreased circulating interleukin-12 level J:96123
decreased dendritic cell number J:100867, J:113232, J:96123
decreased interferon-gamma secretion J:96123
decreased interleukin-4 secretion J:96123
decreased interleukin-12b secretion J:125611
immune system phenotype J:122114, J:96123
impaired natural killer cell mediated cytotoxicity J:125611
sepsis J:113232
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/0
(C.FVB-1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/J)
abnormal NK cell physiology J:96123
decreased circulating interferon-gamma level J:96123
decreased circulating interleukin-12 level J:96123
decreased dendritic cell number J:96123
decreased interferon-gamma secretion J:96123
immune system phenotype J:96123
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/0
(involves: C57BL/6 * FVB/N)
abnormal alveolar macrophage morphology J:137452
decreased dendritic cell number J:137452
decreased interferon-gamma secretion J:137452
increased susceptibility to Orthomyxoviridae infection J:137452
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/0
(NOD.FVB-1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/Jdk)
abnormal professional antigen presenting cell physiology J:137009
decreased dendritic cell number J:137009
decreased macrophage cell number J:137009
decreased NK T cell number J:137009
decreased susceptibility to autoimmune diabetes J:137009
increased interferon-gamma secretion J:137009
increased tumor necrosis factor secretion J:137009
insulitis J:137009
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/0
(involves: FVB/N)
abnormal response to infection J:189122
decreased gamma-delta T cell number J:193548
decreased interleukin-17 secretion J:193548
decreased leukocyte cell number J:193548
decreased neutrophil cell number J:193548
decreased susceptibility to bacterial infection J:210086
decreased T cell number J:193548
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/0
(B6.FVB-1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan)
abnormal circulating cytokine level J:194800
abnormal susceptibility to infection J:194800
decreased dendritic cell number J:194800
decreased neutrophil cell number J:194800
impaired neutrophil recruitment J:194800
increased monocyte cell number J:194800
increased neutrophil cell number J:194800
increased susceptibility to bacterial infection J:194800
1700019D03Riktm1.1(NCOM)Mfgc/1700019D03Riktm1.1(NCOM)Mfgc
(C57BL/6N-1700019D03Riktm1.1(NCOM)Mfgc/Tcp)
enlarged lymph nodes J:211773
1700025G04Rikem1(IMPC)Mbp/1700025G04Rikem1(IMPC)Mbp
(C57BL/6NCrl-1700025G04Rikem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
1700034E13Rikem1(IMPC)Mbp/1700034E13Rikem1(IMPC)Mbp
(C57BL/6NCrl-1700034E13Rikem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
1700067K01Riktm2a(KOMP)Wtsi/1700067K01Riktm2a(KOMP)Wtsi
(C57BL/6N-1700067K01Riktm2a(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
1700069L16Rikem1(IMPC)Mbp/1700069L16Rikem1(IMPC)Mbp
(C57BL/6NCrl-1700069L16Rikem1(IMPC)Mbp/Mmucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
2310022B05Riktm1a(EUCOMM)Hmgu/2310022B05Riktm1a(EUCOMM)Hmgu
(C57BL/6N-2310022B05Riktm1a(EUCOMM)Hmgu/H)
increased B cell number J:165965
increased leukocyte cell number J:165965
2810408A11Riktm1a(EUCOMM)Wtsi/2810408A11Riktm1a(EUCOMM)Wtsi
(C57BL/6N-2810408A11Riktm1a(EUCOMM)Wtsi/H)
decreased NK cell number J:165965
increased CD4-positive, alpha-beta T cell number J:165965
increased NK cell number J:165965
3425401B19Rikem2(IMPC)Ccpcz/3425401B19Rikem2(IMPC)Ccpcz
(C57BL/6NCrl-3425401B19Rikem2(IMPC)Ccpcz/Ph)
increased effector memory T-helper cell number J:211773
increased eosinophil cell number J:211773
4933434E20Riktm1a(EUCOMM)Wtsi/4933434E20Riktm1a(EUCOMM)Wtsi
(C57BL/6N-4933434E20Riktm1a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
enlarged lymphatic vessel J:239583
6430548M08Rikem1(IMPC)Mbp/6430548M08Rikem1(IMPC)Mbp
(C57BL/6N-6430548M08Rikem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
9030622O22Rikem1Eem/9030622O22Rik+
Foxa2tm1.1Khk/Foxa2+

(involves: 129P2/OlaHsd * C57BL/6 * CD-1)
respiratory system inflammation J:284174
9030622O22Rikem1Eem/9030622O22Rikem1Eem
(involves: C57BL/6 * CD-1)
lung inflammation J:284174
9430015G10Riktm1Lex/9430015G10Riktm1Lex
(B6;129S5-9430015G10Riktm1Lex/Mmucd)
decreased CD4-positive, alpha-beta T cell number J:171883
increased B cell number J:171883
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Tg(Myh6-2A)#Know/0

(involves: BALB/c * C57BL/6 * FVB/N)
heart inflammation J:128060
A2ml1em1(IMPC)Tcp/A2ml1+
(C57BL/6N-A2ml1em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
A2ml1em1(IMPC)Tcp/A2ml1em1(IMPC)Tcp
(C57BL/6N-A2ml1em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
A3galt2tm1.1Hjg/A3galt2tm1.1Hjg
(involves: 129P2/OlaHsd * BALB/cJ)
immune system phenotype J:120323
A4galttm1.1Poru/A4galttm1.1Poru
Glatm1Kul/Glatm1Kul

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
immune system phenotype J:189359
A4gnttm1Jnaka/A4gnttm1Jnaka
(B6.129S6-A4gnttm1Jnaka)
stomach inflammation J:184485
A930024E05Rikem2Zfa/A930024E05Rikem2Zfa
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
immune system phenotype J:259392
A930024E05Rikem2Zfa/A930024E05Rikem2Zfa
Satb1em1Zfa/Satb1em1Zfa
Tg(Rorc-cre)1Litt/0

(involves: C57BL/6 * FVB)
increased susceptibility to bacterial infection J:259392
increased susceptibility to bacterial infection induced morbidity/mortality J:259392
A930024E05Rikem2Zfa/A930024E05Rikem2Zfa
Tg(Rorc-cre)1Litt/0

(involves: C57BL/6 * FVB)
abnormal interleukin secretion J:259392
increased susceptibility to bacterial infection J:259392
increased susceptibility to bacterial infection induced morbidity/mortality J:259392
Atm1Brd/Atm1Brd
Ypel4tm1a(EUCOMM)Wtsi/Ypel4tm1a(EUCOMM)Wtsi

(C57BL/6N-Atm1Brd Ypel4tm1a(EUCOMM)Wtsi/WtsiIeg)
immune system phenotype J:313842
Ay/a
Apoetm1Unc/Apoetm1Unc

(involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl)
abnormal inflammatory response J:177084
increased monocyte cell number J:177084
AA467197em1Nyam/AA467197em1Nyam
(C57BL/6J-AA467197em1Nyam)
abnormal thymus cortex morphology J:347271
abnormal thymus medulla morphology J:347271
decreased CD4-positive, alpha-beta T cell number J:347271
increased IgG level J:347271
kidney inflammation J:347271
liver inflammation J:347271
lung inflammation J:347271
AA467197em1Nyam/AA467197em1Nyam
(C.B6-AA467197em1Nyam)
increased susceptibility to autoimmune disorder J:347271
AabprNZB/Slc/?
(involves: NZB/Slc * NZW/Slc)
increased B cell proliferation J:87690
Aadacem1(IMPC)Mbp/Aadacem1(IMPC)Mbp
(C57BL/6NCrl-Aadacem1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
small thymus J:211773
Aars2tm1(KOMP)Wtsi/Aars2+
(C57BL/6N-Aars2tm1(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
Aassem1(IMPC)Tcp/Aassem1(IMPC)Tcp
(C57BL/6NCrl-Aassem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Abca1tm1Jdm/Abca1tm1Jdm
(DBA/1LacJ-Abca1tm1Jdm)
enlarged spleen J:60210
impaired macrophage phagocytosis J:63265
Abca1tm1Jdm/Abca1tm1Jdm
(involves: C57BL/6 * DBA/1LacJ)
abnormal thymus morphology J:132254
impaired macrophage phagocytosis J:132254
Abca1tm1Jdm/Abca1tm1Jdm
Abcg1tm1Dgen/Abcg1tm1Dgen

(involves: 129P2/OlaHsd * C57BL/6 * DBA/1LacJ)
abnormal chemokine secretion J:130777
abnormal cytokine secretion J:130777
Abca1tm1Jdm/Abca1tm1Jdm
Abcg1tm1Dgen/Abcg1tm1Dgen

(involves: 129P2/OlaHsd * C57BL/6 * DBA * DBA/1LacJ)
decreased monocyte cell number J:190966
increased monocyte cell number J:190966
increased neutrophil cell number J:190966
Abca1tm1Jdm/Abca1tm1Jdm
Tgm2tm1Gml/Tgm2tm1Gml

(involves: C57BL/6 * DBA/1LacJ)
abnormal thymus morphology J:132254
impaired macrophage phagocytosis J:132254
Abca1tm1Jp/Abca1tm1Jp
Abcg1tm1Tall/Abcg1tm1Tall
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6)
increased interleukin-17 secretion J:190966
increased interleukin-23 secretion J:190966
Abca1tm1Jp/Abca1tm1Jp
Abcg1tm1Tall/Abcg1tm1Tall
Tg(Itgax-cre,-EGFP)4097Ach/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J)
increased interleukin-17 secretion J:190966
increased interleukin-23 secretion J:190966
Abca1tm1Wpfl/Abca1tm1Wpfl
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal thymus morphology J:64390
glomerulonephritis J:64390
uterus inflammation J:64390
Abca5em1(IMPC)Ccpcz/Abca5em1(IMPC)Ccpcz
(C57BL/6NCrl-Abca5em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Abcb1amds/Abcb1amds
(involves: CF-1)
increased eosinophil cell number J:64725
Abcb1atm1Bor/Abcb1atm1Bor
(FVBTac.129P2-Abcb1atm1Bor)
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:102640
decreased gamma-delta intraepithelial T cell number J:102640
Abcb1atm1Bor/Abcb1atm1Bor
(FVB.129P2-Abcb1atm1Bor/TacImx)
abnormal lymphocyte physiology J:51190
colitis J:51190
increased IgA level J:51190
increased IgE level J:51190
increased IgG1 level J:51190
increased IgG2 level J:51190
increased IgG2a level J:51190
increased IgG2b level J:51190
increased IgG3 level J:51190
increased IgM level J:51190
increased immunoglobulin level J:51190
large intestinal inflammation J:51190
Abcb1atm1Bor/Abcb1atm1Bor
Abcb1btm1Bor/Abcb1btm1Bor

(FVBTac.129P2-Abcb1btm1Bor Abcb1atm1Bor)
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:102640
abnormal T cell physiology J:102640
decreased gamma-delta intraepithelial T cell number J:102640
increased double-positive T cell number J:102640
increased interferon-gamma secretion J:102640
increased interleukin-2 secretion J:102640
Abcb4em1(IMPC)H/Abcb4em1(IMPC)H
(C57BL/6NTac-Abcb4em1(IMPC)H/H)
increased basophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Abcb4tm1Bor/Abcb4tm1Bor
(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * FVB/N))
bile duct inflammation J:15531, J:21232
liver inflammation J:15531
Abcb4tm1Bor/Abcb4tm1Bor
(involves: 129P2/OlaHsd * FVB/N)
bile duct inflammation J:175015
liver inflammation J:175015
Abcb4tm1Bor/Abcb4tm1Bor
(FVB.129P2-Abcb4tm1Bor/J)
bile duct inflammation J:105357
enlarged spleen J:217802
Abcb4tm1Bor/Abcb4tm1Bor
(involves: 129P2/OlaHsd * BALB/c)
bile duct inflammation J:168123
Abcb4tm1Bor/Abcb4tm1Bor
(CAnNCrl.12P2(FVB)-Abcb4tm1Bor)
enlarged spleen J:217802
Abcb9tm1b(KOMP)Wtsi/Abcb9tm1b(KOMP)Wtsi
(C57BL/6N-Abcb9tm1b(KOMP)Wtsi/Tcp)
enlarged lymph nodes J:211773
Abcc1tm1Bor/Abcc1tm1Bor
(involves: 129P2/OlaHsd * FVB)
abnormal mast cell physiology J:44110
decreased inflammatory response J:44110
Abcc1tm1Bor/Abcc1tm1Bor
Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/0

(FVB.Cg-Abcc1tm1Bor Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr)
microgliosis J:178230
Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
(C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Abcc4tm1Kruh/Abcc4tm1Kruh
(B6.129-Abcc4tm1Kruh)
abnormal spleen B cell follicle morphology J:117326
abnormal spleen red pulp morphology J:117326
decreased spleen B cell follicle number J:117326
decreased spleen B cell follicle size J:117326
increased susceptibility to induced colitis J:117326
intestinal inflammation J:117326
small intestinal inflammation J:117326
small spleen J:117326
thymus cortex hypoplasia J:117326
Abcc5em1(IMPC)H/Abcc5em1(IMPC)H
(C57BL/6N-Abcc5em1(IMPC)H/H)
decreased eosinophil cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
Abcc9em1(IMPC)H/Abcc9+
(C57BL/6N-Abcc9em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Abcc10tm1Eah/Abcc10tm1Eah
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal spleen red pulp morphology J:172648
decreased leukocyte cell number J:172648
decreased spleen germinal center number J:172648
decreased spleen germinal center size J:172648
decreased spleen white pulp amount J:172648
small spleen J:172648
thymus cortex hypoplasia J:172648
Abcd1tm1Kds/Y
(involves: 129S4/SvJae * C57BL/6J)
abnormal microglial cell morphology J:94583
Abcd1tm1Kds/Y
Abcd2tm1Apuj/Abcd2tm1Apuj

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J)
abnormal microglial cell morphology J:94583
increased inflammatory response J:94583
Abcd2tm1Apuj/Abcd2tm1Apuj
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal microglial cell morphology J:94583
Abce1tm1.1(KOMP)Vlcg/Abce1+
(C57BL/6N-Abce1tm1.1(KOMP)Vlcg/Tcp)
enlarged lymph nodes J:211773
increased neutrophil cell number J:211773
Abce1tm1b(EUCOMM)Hmgu/Abce1+
(C57BL/6N-Abce1tm1b(EUCOMM)Hmgu/H)
increased large unstained cell number J:211773
Abcg1tm1Dgen/Abcg1tm1Dgen
(B6.129P2-Abcg1tm1Dgen)
abnormal macrophage physiology J:117028
increased macrophage derived foam cell number J:117028
Abcg1tm1Dgen/Abcg1tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6)
abnormal chemokine secretion J:130777
abnormal cytokine secretion J:130777
abnormal leukocyte morphology J:132952
abnormal macrophage morphology J:132952
abnormal monocyte differentiation J:132952
increased B cell number J:132952
increased CD4-positive, alpha-beta T cell number J:132952
increased CD8-positive, alpha-beta T cell number J:132952
increased dendritic cell number J:132952
increased eosinophil cell number J:132952
increased monocyte cell number J:132952
increased neutrophil cell number J:132952
lung inflammation J:132952
Abcg2tm1.1Ssf/Abcg2tm1.1Ssf
(involves: 129 * C57BL/6 * FVB)
liver inflammation J:201884
Abcg5trac/Abcg5trac
(A/J-Abcg5trac)
abnormal neutrophil morphology J:157223
decreased leukocyte cell number J:157223
Abcg8tm1b(KOMP)Wtsi/Abcg8tm1b(KOMP)Wtsi
(C57BL/6N-Abcg8tm1b(KOMP)Wtsi/Ccpcz)
abnormal spleen morphology J:211773
decreased B-2 B cell number J:211773
decreased CD4-negative NK T cell number J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
decreased NK T cell number J:211773
decreased T cell number J:211773
enlarged spleen J:211773
immune system phenotype J:211773
Abhd5tm1.1Lqyu/Abhd5tm1.1Lqyu
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * DBA)
liver inflammation J:199570
Abhd5tm1.1Rze/Abhd5tm1.1Rze
(involves: 129P2/OlaHsd * C57BL/6)
abnormal granulocyte morphology J:160725
Abhd10em1(IMPC)Mbp/Abhd10em1(IMPC)Mbp
(C57BL/6NCrl-Abhd10em1(IMPC)Mbp/Mmucd)
increased eosinophil cell number J:211773
Abhd12tm1Crv/Abhd12tm1Crv
(involves: C57BL/6)
microgliosis J:193716
Abhd13em1(IMPC)Mbp/Abhd13em1(IMPC)Mbp
(C57BL/6NCrl-Abhd13em1(IMPC)Mbp/Mmucd)
decreased spleen weight J:211773
Abhd16atm1a(EUCOMM)Wtsi/Abhd16atm1a(EUCOMM)Wtsi
(involves: C57BL/6N * C57BL/6NTac)
abnormal macrophage physiology J:232688
decreased interleukin-1 beta secretion J:232688
decreased interleukin-6 secretion J:232688
decreased macrophage cytokine production J:232688
decreased tumor necrosis factor secretion J:232688
Abhd17cem1(IMPC)Mbp/Abhd17cem1(IMPC)Mbp
(C57BL/6N-Abhd17cem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Abi1tm1Pen/Abi1+
Abi2tm1Pen/Abi2tm1Pen

(Not Specified)
decreased interleukin-2 secretion J:104623
decreased T cell proliferation J:104623
immune system phenotype J:104623
Abl1m1/Abl1m1
(either: 129S/SvEv-Abl1m1 or (involves: 129S/SvEv * CD-1) or (involves: 129S/SvEv * C57BL/6 * DBA/2))
abnormal B cell differentiation J:14644
abnormal immune system cell morphology J:14644
abnormal immune system organ morphology J:14644
abnormal spleen germinal center morphology J:14644
abnormal spleen morphology J:14644
abnormal spleen white pulp morphology J:14644
abnormal T cell number J:14644
abnormal thymus morphology J:14644
decreased immature B cell number J:14644
decreased pre-B cell number J:14644
decreased pro-B cell number J:14644
decreased single-positive T cell number J:14644
decreased thymocyte number J:14644
increased single-positive T cell number J:14644
increased susceptibility to infection J:14644
spleen hypoplasia J:14644
thymus cortex hypoplasia J:14644
thymus hypoplasia J:14644
Abl1m1/Abl1m1
(involves: 129S/SvEv)
abnormal B cell differentiation J:28795
abnormal immune system cell morphology J:34903
abnormal splenocyte physiology J:34903
decreased mature B cell number J:28795
decreased pre-B cell number J:28795
decreased pro-B cell number J:28795
Abl1m1/Abl1m1
(involves: 129S/SvEv * C57BL/6)
abnormal B cell physiology J:148105
abnormal lymphopoiesis J:148105
decreased pro-B cell number J:148105
Abl1tm1Mlg/Abl1tm1Mlg
(involves: 129S/SvEv * C57BL/6J)
decreased B cell number J:72875
decreased lymphocyte cell number J:72875
decreased T cell number J:72875
decreased thymocyte number J:72875
lung inflammation J:72875
spleen atrophy J:72875
thymus atrophy J:72875
Abl1tm1Mlg/Abl1tm1Mlg
(involves: 129S/SvEv * C57BL/6J * CBA)
abnormal spleen morphology J:34643
increased susceptibility to infection J:34643
Abl1tm1Mlg/Abl1tm1Mlg
Tg(ACTB-Abl1*K290R)1Spg/0

(involves: 129S/SvEv * C57BL/6J * CBA)
abnormal spleen morphology J:34643
increased susceptibility to infection J:34643
Abl1tm2.2Goff/Abl1tm2.2Goff
(involves: 129P2/OlaHsd * C57BL/6J * FVB/N)
spleen atrophy J:166211
thymus atrophy J:166211
Ablim3em1(IMPC)Tcp/Ablim3em1(IMPC)Tcp
(C57BL/6N-Ablim3em1(IMPC)Tcp/Tcp)
decreased basophil cell number J:211773
enlarged lymph nodes J:211773
AbmmDBA/2J/?
(involves: BALB/cByJ * DBA/2J)
myocarditis J:52296
Abtb1em1(IMPC)Ccpcz/Abtb1em1(IMPC)Ccpcz
(C57BL/6N-Abtb1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Abtb2tm1a(KOMP)Wtsi/Abtb2tm1a(KOMP)Wtsi
(C57BL/6N-Atm1Brd Abtb2tm1a(KOMP)Wtsi/WtsiH)
decreased leukocyte cell number J:211773
Acacatm1Dejs/Acacatm1Dejs
Tg(Cd4-cre)1Cwi/?

(involves: C57BL/6 * DBA/2)
abnormal T cell physiology J:209886
decreased memory T cell number J:209886
decreased T cell number J:209886
immune system phenotype J:209886
Acacatm1Dejs/Acacatm1Dejs
Tg(Cd4-cre)1Cwi/?
Tg(TcraTcrb)1100Mjb/?

(involves: C57BL/6 * DBA/2)
increased T cell proliferation J:209886
Acad10em1(IMPC)Tcp/Acad10em1(IMPC)Tcp
(C57BL/6N-Acad10em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Acantm2Afos/Acantm2Afos
(involves: C57BL/6)
decreased susceptibility to induced arthritis J:122102
Acbd5tm1a(EUCOMM)Wtsi/Acbd5tm1a(EUCOMM)Wtsi
(C57BL/6N-Atm1Brd Acbd5tm1a(EUCOMM)Wtsi/WtsiCnbc)
abnormal microglial cell morphology J:299448
brain inflammation J:299448
Ace2em1(ACE2)Yowa/Ace2em1(ACE2)Yowa
(C57BL/6-Ace2em1(ACE2)Yowa)
abnormal circulating cytokine level J:288243
increased circulating interferon-gamma level J:288243
increased circulating interleukin-9 level J:288243
increased susceptibility to Coronaviridae infection J:288243
interstitial pneumonia J:288243
Ace2em1(IMPC)Ccpcz/Y
(C57BL/6NCrl-Ace2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Ace2em1(IMPC)Ccpcz/Ace2em1(IMPC)Ccpcz
(C57BL/6NCrl-Ace2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Ace2em1Cya/Y
(C57BL/6J-Ace2em1Cya/Cya)
increased susceptibility to induced colitis J:299383
intestinal inflammation J:299383
Ace2em2(ACE2)Gpt/Y
(C57BL/6JGpt-Ace2em2(ACE2)Gpt/Gpt)
increased susceptibility to Coronaviridae infection J:302150
lung inflammation J:302150
Ace2em#Yngh/Y
(involves: Kunming)
increased susceptibility to induced colitis J:221616
Ace2tm1a(KOMP)Wtsi/Y
Tg(FOXJ1-cre)F26Htzm/0

(involves: C57BL/6N * C57BL/6NTac)
increased neutrophil cell number J:282139
increased susceptibility to bacterial infection J:282139
increased susceptibility to bacterial infection induced morbidity/mortality J:282139
lung inflammation J:282139
Ace2tm1a(KOMP)Wtsi/Ace2tm1a(KOMP)Wtsi
Tg(FOXJ1-cre)F26Htzm/0

(involves: C57BL/6N * C57BL/6NTac)
increased neutrophil cell number J:282139
increased susceptibility to bacterial infection J:282139
increased susceptibility to bacterial infection induced morbidity/mortality J:282139
lung inflammation J:282139
Ace2tm1Cof/Ace2tm1Cof
(involves: 129S6/SvEvTac * C57BL/6)
increased incidence of corneal inflammation J:289503
Ace2tm1Lex/Ace2tm1Lex
(B6;129S5-Ace2tm1Lex/Mmucd)
lung inflammation J:264991
Ace2tm1Pngr/Y
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine level J:124548
heart inflammation J:124548
Ace2tm1Pngr/Y
(B6.129P2-Ace2tm1Pngr/J)
decreased susceptibility to Coronaviridae infection J:286299
Ace2tm1Pngr/Y
(involves: 129P2/OlaHsd)
increased neutrophil cell number J:282139
increased susceptibility to bacterial infection J:282139
increased susceptibility to bacterial infection induced morbidity/mortality J:282139
lung inflammation J:282139, J:100334
Ace2tm1Pngr/Y
(involves: 129P2/OlaHsd * C57BL/6J)
increased susceptibility to Orthomyxoviridae infection J:277074
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:277074
lung inflammation J:277074
Ace2tm1Pngr/Ace2tm1Pngr
(involves: 129P2/OlaHsd)
increased neutrophil cell number J:282139
increased susceptibility to bacterial infection J:282139
increased susceptibility to bacterial infection induced morbidity/mortality J:282139
lung inflammation J:282139, J:100334
Ace2tm1Pngr/Ace2tm1Pngr
(involves: 129P2/OlaHsd * C57BL/6J)
increased susceptibility to Orthomyxoviridae infection J:277074
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:277074
lung inflammation J:277074
Ace2tm1Pngr/Ace2tm1Pngr
(B6.129P2-Ace2tm1Pngr/J)
decreased susceptibility to Coronaviridae infection J:286299
Acetm1.1(KOMP)Vlcg/Ace+
(C57BL/6N-Acetm1.1(KOMP)Vlcg/MbpMmucd)
increased basophil cell number J:211773
Acetm1Keb/Acetm1Keb
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
kidney inflammation J:33018
Acetm1Mcf/Acetm1Mcf
(Not Specified)
kidney inflammation J:32114
tubulointerstitial nephritis J:32114
Acetm1Unc/Acetm1Unc
(involves: 129P2/OlaHsd * C57BL/6J)
kidney inflammation J:25284
Acetm6Keb/Acetm6Keb
(involves: 129 * C57BL/6)
abnormal interleukin level J:122178
increased T cell number J:122178
Acetm9Keb/Acetm9Keb
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
kidney inflammation J:185888
Acer1tm1a(EUCOMM)Wtsi/Acer1tm1a(EUCOMM)Wtsi
(C57BL/6N-Acer1tm1a(EUCOMM)Wtsi)
increased eosinophil cell number J:235775
skin inflammation J:235775
Acheem1(IMPC)Mbp/Ache+
(C57BL/6N-Acheem1(IMPC)Mbp/MbpMmucd)
increased neutrophil cell number J:211773
Ackr1tm1Scp/Ackr1tm1Scp
(involves: 129P2/OlaHsd * C57BL/6)
increased inflammatory response J:64222
Ackr1tm1Scp/Ackr1tm1Scp
(involves: 129P2/OlaHsd)
abnormal circulating chemokine level J:162629
Ackr1tm1Skmz/Ackr1tm1Skmz
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal chemokine level J:82938
Ackr2tm1Gjg/Ackr2tm1Gjg
(involves: 129/Sv * C57BL/6)
dermatitis J:97607
increased inflammatory response J:97806
Ackr3tm1.1Fma/Ackr3tm1.1Fma
(involves: BALB/cJ * C57BL/6)
decreased marginal zone B cell number J:124878
Ackr3tm1.1Rodb/Ackr3tm1.1Rodb
(involves: 129S6/SvEvTac * BALB/cJ * C57BL/6)
immune system phenotype J:165184
Ackr3tm1Jgo/Ackr3+
(involves: 129S/SvEvBrd * C57BL/6)
lung inflammation J:136246
Ackr3tm1Jgo/Ackr3tm1Jgo
(involves: 129S/SvEvBrd * C57BL/6)
lung inflammation J:136246
Ackr4tm1.1Rjbn/Ackr4tm1.1Rjbn
(B6.129S6-Ackr4tm1.1Rjbn)
abnormal CD4-positive, alpha-beta T cell number J:166490
abnormal CD4-positive, alpha-beta T cell physiology J:166490
abnormal chemokine level J:166490
abnormal circulating chemokine level J:166490
abnormal T-helper 17 cell differentiation J:166490
decreased T cell proliferation J:166490
increased interleukin-23 secretion J:166490
increased susceptibility to experimental autoimmune encephalomyelitis J:166490
increased T-helper 17 cell number J:166490
spleen hyperplasia J:166490
Acla1BXSB/Slc/Acla1BXSB/Slc
(involves: BXSB/Slc * NZW/Slc)
increased autoantibody level J:49899
Acla1NZW/Slc/Acla1BXSB/Slc
(involves: BXSB/Slc * NZW/Slc)
increased autoantibody level J:49899
Acla2BXSB/Slc/Acla2BXSB/Slc
(involves: BXSB/Slc * NZW/Slc)
increased autoantibody level J:49899
Acla2NZW/Slc/Acla2BXSB/Slc
(involves: BXSB/Slc * NZW/Slc)
increased autoantibody level J:49899
Acod1tm1a(KOMP)Wtsi/Acod1tm1a(KOMP)Wtsi
(involves: C57BL/6N)
abnormal macrophage physiology J:235002
Acot11tm1Deco/Acot11tm1Deco
(involves: 129S6/SvEvTac * C57BL/6)
decreased inflammatory response J:182660
Acox1lampe1/Acox1lampe1
(involves: C57BL/6J)
liver inflammation J:174942
Acox2em1Jynz/Acox2em1Jynz
(involves: C57BL/6N)
liver inflammation J:323193
Acoxlem1(IMPC)Mbp/Acoxlem1(IMPC)Mbp
(C57BL/6NCrl-Acoxlem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Acp1tm1Lex/Acp1tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased interleukin-6 secretion J:171883
Acp2tm1a(EUCOMM)Wtsi/Acp2tm1a(EUCOMM)Wtsi
(C57BL/6N-Acp2tm1a(EUCOMM)Wtsi/H)
decreased CD4-positive, alpha-beta T cell number J:165965
decreased CD8-positive, alpha-beta T cell number J:165965
decreased T cell number J:165965
increased B cell number J:165965
Acp2tm1Psa/Acp2tm1Psa
(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J)
abnormal microglial cell morphology J:41986
Acp5tm1Ahdm/Acp5tm1Ahdm
(involves: 129S/SvEv)
abnormal osteoclast physiology J:36232
Acsl3Gt(OST148301)Lex/Acsl3Gt(OST148301)Lex
(B6;129S5-Acsl3Gt(OST148301)Lex/Orl)
abnormal humoral immune response J:82809
decreased B cell number J:82809
increased CD4-positive, alpha-beta T cell number J:82809
Acsl5tm1.1(KOMP)Vlcg/Acsl5tm1.1(KOMP)Vlcg
(C57BL/6N-Acsl5tm1.1(KOMP)Vlcg/Ucd)
increased spleen weight J:211773
Acsl6tm1.1Jeme/Acsl6tm1.1Jeme
(involves: BALB/cJ * C57BL/6)
abnormal microglial cell activation J:267563
Acsm1em1(IMPC)Mhzh/Acsm1em1(IMPC)Mhzh
(C57BL/6N-Acsm1em1(IMPC)Mhzh/Mhzh)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Acsns1A/J/Acsns1A/J
(involves: A/J * SM/J)
decreased susceptibility to parasitic infection J:75549
Acsns2SM/J/Acsns2SM/J
(involves: A/J * SM/J)
increased susceptibility to parasitic infection J:75549
Acsns2SM/J/Acsns2SM/J
Acsns3SM/J/Acsns3SM/J

(involves: A/J * SM/J)
increased susceptibility to parasitic infection J:75549
Acsns3SM/J/Acsns3SM/J
(involves: A/J * SM/J)
increased susceptibility to parasitic infection J:75549
Acss2em22Gpt/Acss2em22Gpt
(C57BL/6JGpt-Acss2em22Gpt/Gpt)
decreased interleukin-1 beta secretion J:346990
decreased susceptibility to endotoxin shock J:346990
Actbtm4(cre/ERT2)Npa/Actb+
Sgpl1tm1.1Npa/Sgpl1tm1.1Npa

(involves: BALB/cJ * C57BL/6)
abnormal lymph node morphology J:199525
abnormal regulatory T cell number J:199525
abnormal type IV hypersensitivity reaction J:199525
decreased follicular B cell number J:199525
decreased marginal zone B cell number J:199525
decreased single-positive T cell number J:199525
decreased susceptibility to experimental autoimmune encephalomyelitis J:199525
increased thymocyte number J:199525
spleen hypoplasia J:199525
Actl6atm1.1Grc/Actl6a+
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6J * CBA)
decreased granulocyte number J:192124
decreased macrophage cell number J:192124
Actl6atm1.1Grc/Actl6atm1.1Grc
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6J * CBA)
decreased B cell number J:192124
decreased granulocyte number J:192124
decreased leukocyte cell number J:192124
decreased lymphocyte cell number J:192124
decreased macrophage cell number J:192124
decreased monocyte cell number J:192124
Actn4tm1a(EUCOMM)Wtsi/Actn4tm1a(EUCOMM)Wtsi
(C57BL/6N-Actn4tm1a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Actn4tm1Mrpk/Actn4tm1Mrpk
(involves: 129 * C57BL/6)
abnormal lymphocyte chemotaxis J:83911
Acvr1tm1Emsh/Acvr1+
(chimera involves: BALB/c * C57BL/6 * CD-1)
increased inflammatory response J:194134
Acvr1btm1.1(KOMP)Vlcg/Acvr1b+
(C57BL/6N-Acvr1btm1.1(KOMP)Vlcg/Ucd)
enlarged lymph nodes J:211773
Acvr2atm1.1(KOMP)Vlcg/Acvr2a+
(C57BL/6N-Acvr2atm1.1(KOMP)Vlcg/Ucd)
decreased eosinophil cell number J:211773
decreased neutrophil cell number J:211773
Acvr2btm1Enl/Acvr2btm1Enl
(either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6J))
abnormal spleen morphology J:42018
small spleen J:42018
Adatm1Mw/Adatm1Mw
(involves: 129S7/SvEvBrd * C57BL/6)
decreased T cell number J:25085
Adatm1Mw/Adatm1Mw
(involves: 129S7/SvEvBrd)
abnormal dendritic cell physiology J:138722
increased dendritic cell number J:138722
Adatm1Mw/Adatm1Mw
Tg(PLADA)4118Rkmb/0

(involves: 129S7/SvEvBrd * C57BL/6)
abnormal spleen red pulp morphology J:73418
abnormal thymus corticomedullary boundary morphology J:73418
decreased double-positive T cell number J:73418
decreased immunoglobulin level J:73418
decreased leukocyte cell number J:73418
increased double-negative T cell number J:73418
increased eosinophil cell number J:73418
increased granulocyte number J:73418
increased macrophage cell number J:73418
lung inflammation J:73418
small spleen J:73418
small thymus J:73418
spleen hypoplasia J:73418
Adam7tm1Tigm/Adam7tm1Tigm
(involves: C57BL/6)
spermatic granuloma J:226260
Adam8tm1.1Mdz/Adam8tm1.1Mdz
(DBA/1LacJ-Adam8tm1.1Mdz)
decreased susceptibility to induced arthritis J:155243
immune system phenotype J:155243
Adam8tm1.1Rood/Adam8tm1.1Rood
(involves: 129/Sv * C57BL/6 * FVB/N)
abnormal osteoclast differentiation J:172936
Adam10tm1.1Dhc/Adam10tm1.1Dhc
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL)
abnormal B cell differentiation J:158127
absent marginal zone B cells J:158127
decreased transitional stage T2 B cell number J:158127
increased follicular B cell number J:158127
increased transitional stage T1 B cell number J:158127
Adam10tm1.1Khr/Adam10tm1.1Khr
Csf3rtm1Link/Csf3rtm1Link
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6N)
abnormal granulocyte differentiation J:179060
enlarged spleen J:179060
myeloid hyperplasia J:179060
spleen hyperplasia J:179060
Adam10tm1.1Khr/Adam10tm1.1Khr
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N)
abnormal granulocyte differentiation J:179060
abnormal spleen morphology J:179060
abnormal T cell differentiation J:179060
decreased CD4-positive, alpha-beta T cell number J:179060
decreased CD8-positive, alpha-beta T cell number J:179060
decreased double-positive T cell number J:179060
decreased T cell number J:179060
enlarged spleen J:179060
increased leukocyte cell number J:179060
increased neutrophil cell number J:179060
increased spleen red pulp amount J:179060
increased spleen weight J:179060
myeloid hyperplasia J:179060
small thymus J:179060
spleen hyperplasia J:179060
thymus hypoplasia J:179060
Adam10tm1Zhu/Adam10tm1.1Zhu
Tg(Lck-cre)#Zhu/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL * SJL/J)
abnormal T cell differentiation J:139042
decreased CD4-positive, alpha-beta T cell number J:139042
decreased double-positive T cell number J:139042
thymus hypoplasia J:139042
Adam10tm1Zhu/Adam10tm1Zhu
Tg(Lck-cre)#Zhu/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL/J)
abnormal T cell differentiation J:139042
decreased CD4-positive, alpha-beta T cell number J:139042
decreased double-positive T cell number J:139042
thymus hypoplasia J:139042
Adam17m1Btlr/Adam17m1Btlr
(C57BL/6J-Adam17m1Btlr)
decreased circulating tumor necrosis factor level J:166602
increased susceptibility to induced colitis J:166602
Adam17tm1.1Srj/Adam17tm1.1Srj
(involves: 129S/SvEv * C57BL/6 * SJL)
abnormal chemokine level J:163380
abnormal interleukin secretion J:163380
increased interleukin-10 secretion J:163380
increased susceptibility to induced colitis J:163380
skin inflammation J:163380
Adam17tm1.2Bbl/Adam17tm1.2Bbl
Il17atm1Yiw/Il17atm1Yiw
Sox9tm3(cre)Crm/Sox9+

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * SJL)
dermatitis J:229771
Adam17tm1.2Bbl/Adam17tm1.2Bbl
Il23atm1Dnax/Il23atm1Dnax
Sox9tm3(cre)Crm/Sox9+

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * SJL)
dermatitis J:229771
Adam17tm1.2Bbl/Adam17tm1.2Bbl
Sox9tm3(cre)Crm/Sox9+

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
abnormal spleen morphology J:144795
decreased B cell number J:144795
decreased lymphocyte cell number J:144795
decreased T cell number J:144795
enlarged spleen J:144795
increased circulating interleukin-17 level J:144795
increased interleukin-17 secretion J:144795
increased leukocyte cell number J:144795
increased macrophage cell number J:144795
increased neutrophil cell number J:144795
increased spleen red pulp amount J:144795
Adam17tm1.2Bbl/Adam17tm1.2Bbl
Sox9tm3(cre)Crm/Sox9+

(B6.129(SJL)-Sox9tm3(cre)Crm Adam17tm1.2Bbl)
abnormal circulating chemokine level J:229771
dermatitis J:229771
increased IgE level J:229771
increased T-helper 1 cell number J:229771
increased T-helper 2 cell number J:229771
increased T-helper 17 cell number J:229771
Adam17tm1a(EUCOMM)Wtsi/Adam17+
(involves: C57BL/6 * C57BL/6N)
myeloid hyperplasia J:213427
Adam17tm1Bbl/Adam17tm1Bbl
Lyz2tm1(cre)Ifo/0

(involves: 129P2/OlaHsd)
abnormal macrophage physiology J:139846
decreased circulating tumor necrosis factor level J:139846
decreased susceptibility to endotoxin shock J:139846
Adam17tm1Bbl/Adam17tm1Bbl
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased circulating tumor necrosis factor level J:139846
decreased susceptibility to endotoxin shock J:139846
Adam17tm1Ckww/Adam17tm1Ckww
(Not Specified)
abnormal dendritic cell physiology J:138782
Adam17tm1Imx/Adam17tm1Imx
(involves: 129 * C57BL/6)
increased incidence of corneal inflammation J:51053
Adam17tm1Imx/Adam17tm1Imx
(B6.129-Adam17tm1Imx)
enhanced leukocyte tethering or rolling J:174865
Adam17tm1Rain/Adam17tm1Rain
(involves: C57BL/6)
enhanced leukocyte tethering or rolling J:174865
Adam17woe/Adam17woe
(C57BL/6-Adam17woe)
dermatitis J:160781
increased incidence of corneal inflammation J:160781
Adam28tm1.2Dica/Adam28tm1.2Dica
(B6JRj.129-Adam28tm1.2Dica)
abnormal alpha-beta T cell morphology J:298188
abnormal lymphocyte morphology J:298188
decreased CD8-positive, alpha-beta T cell number J:298188
Adam28tm1.2Dica/Adam28tm1.2Dica
(CJRj.129-Adam28tm1.2Dica)
decreased CD8-positive, alpha-beta T cell number J:298188
Adamdec1tm1Dgen/Adamdec1+
(B6.129P2-Adamdec1tm1Dgen)
increased susceptibility to induced colitis J:301741
Adamdec1tm1Dgen/Adamdec1tm1Dgen
(B6.129P2-Adamdec1tm1Dgen)
decreased circulating interleukin-10 level J:301741
increased circulating interleukin-1 beta level J:301741
increased circulating interleukin-6 level J:301741
increased neutrophil cell number J:301741
increased susceptibility to bacterial infection J:301741
increased susceptibility to bacterial infection induced morbidity/mortality J:301741
increased susceptibility to colitis induced morbidity/mortality J:301741
increased susceptibility to induced colitis J:301741
intestinal inflammation J:301741
Adamts1em1(IMPC)Mbp/Adamts1+
(C57BL/6N-Adamts1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Adamts2tm1Prc/Adamts2tm1Prc
(involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6)
increased interferon-gamma secretion J:271185
Adamts3tm1.2Itl/Adamts3tm1.2Itl
(involves: BALB/cJ * C57BL/6NTac * SJL)
abnormal lymphangiogenesis J:245044
absent lymphatic vessels J:245044
Adamts5tm1.1Eam/Adamts5+
(involves: 129S5/SvEvBrd)
decreased susceptibility to induced arthritis J:97590
Adamts5tm1.1Eam/Adamts5tm1.1Eam
(involves: 129S5/SvEvBrd)
decreased susceptibility to induced arthritis J:97590
Adamts5tm1Lex/Adamts5tm1Lex
Tg(CMV-cre)1Cgn/0

(involves: 129S5/SvEvBrd * BALB/cJ)
osteoarthritis J:105138
Adamts5tm2.2Lex/Adamts5tm2.2Lex
(B6.129S5-Adamts5tm2.2Lex)
decreased susceptibility to induced arthritis J:175366
Adamts6b2b1879.1Clo/Adamts6b2b1879.1Clo
(C57BL/6J-Adamts6b2b1879.1Clo)
thymus hypoplasia J:175213
Adamts6b2b2029Clo/Adamts6b2b2029Clo
(C57BL/6J-Adamts6b2b2029Clo)
thymus hypoplasia J:175213
Adamts6b2b2182Clo/Adamts6b2b2182Clo
(C57BL/6J-Adamts6b2b2182Clo)
thymus hypoplasia J:175213
Adamts6b2b2187.1Clo/Adamts6b2b2187.1Clo
(C57BL/6J-Adamts6b2b2187.1Clo)
thymus hypoplasia J:175213
Adamts6b2b2228Clo/Adamts6b2b2228Clo
(C57BL/6J-Adamts6b2b2228Clo)
thymus hypoplasia J:175213
Adamts6b2b2405Clo/Adamts6b2b2405Clo
(C57BL/6J-Adamts6b2b2405Clo)
thymus hypoplasia J:175213
Adamts6b2b2407Clo/Adamts6b2b2407Clo
(C57BL/6J-Adamts6b2b2407Clo)
thymus hypoplasia J:175213
Adamts6b2b2744Clo/Adamts6b2b2744Clo
(C57BL/6J-Adamts6b2b2744Clo)
thymus hypoplasia J:175213
Adamts6b2b2966.2Clo/Adamts6b2b2966.2Clo
(C57BL/6J-Adamts6b2b2966.2Clo)
thymus hypoplasia J:175213
Adamts9tm1b(KOMP)Wtsi/Adamts9+
(C57BL/6N-Adamts9tm1b(KOMP)Wtsi/MbpMmucd)
abnormal lymph node morphology J:211773
Adamts13tm1Dgi/Adamts13tm1Dgi
(involves: 129X1/SvJ * C57BL/6J * CASA/Rk)
immune system phenotype J:101752
increased susceptibility to bacterial infection J:101752
Adamts14Gt(511E11)Cmhd/Adamts14Gt(511E11)Cmhd
(involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6)
increased interferon-gamma secretion J:271185
increased interleukin-2 secretion J:271185
Adamts14Gt(511E11)Cmhd/Adamts14Gt(511E11)Cmhd
Adamts2tm1Prc/Adamts2tm1Prc

(involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal T cell activation J:271185
cutaneous mastocytosis J:271185
decreased B cell number J:271185
decreased CD8-positive, alpha-beta T cell number J:271185
dermatitis J:271185
increased CD4-positive, alpha-beta T cell number J:271185
increased interferon-gamma secretion J:271185
increased interleukin-2 secretion J:271185
increased T cell proliferation J:271185
Adamts18tm1.1Wzha/Adamts18tm1.1Wzha
(involves: 129 * C57BL/6)
increased acute inflammation J:258487
increased susceptibility to induced colitis J:258487
Adamtsl3em1(IMPC)Tcp/Adamtsl3em1(IMPC)Tcp
(C57BL/6NCrl-Adamtsl3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
small spleen J:211773
Adap1tm1a(EUCOMM)Wtsi/Adap1tm1a(EUCOMM)Wtsi
(C57BL/6N-Adap1tm1a(EUCOMM)Wtsi/Wtsi)
decreased memory-marker NK cell number J:211773
increased NK cell number J:211773
Adarem1Stsn/Adartm1Olds
(involves: 129S/SvEv * C57BL/6J)
abnormal spleen morphology J:308678
Adarem2Qwan/Adarem2Qwan
(Not Specified)
immune system phenotype J:325221
Adarem3Qwan/Adarem3Qwan
(Not Specified)
abnormal chemokine level J:325221
immune system phenotype J:325221
increased circulating interleukin-1 level J:325221
increased circulating interleukin-6 level J:325221
increased circulating interleukin-17 level J:325221
increased CXCL10 level J:325221
Adartm1Olds/Adartm1Olds
(involves: 129S/SvEv * C57BL/6J)
increased susceptibility to Orthomyxoviridae infection J:169014
increased susceptibility to Paramyxoviridae infection J:169014
Adartm2Phs/Adartm2Phs
(B6.Cg-Adartm2Phs)
abnormal circulating interferon-beta level J:142338
increased circulating interferon-alpha level J:142338
Adarb2em1(IMPC)Tcp/Adarb2em1(IMPC)Tcp
(C57BL/6NCrl-Adarb2em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Adaz1NZM2328/J/Adaz1NZM2328/J
(involves: C57L/J * NZM2328/J)
increased anti-double stranded DNA antibody level J:71397
Adck1em2(IMPC)Tcp/Adck1em2(IMPC)Tcp
(C57BL/6NCrl-Adck1em2(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Adcy1tm1b(EUCOMM)Wtsi/Adcy1tm1b(EUCOMM)Wtsi
(C57BL/6N-Adcy1tm1b(EUCOMM)Wtsi/H)
increased leukocyte cell number J:211773
Adcy7tm1.1Pcst/Adcy7tm1.1Pcst
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6J)
increased tumor necrosis factor secretion J:191067
peritoneal inflammation J:191067
Adcy9Gt(OST193739)Lex/Adcy9Gt(OST193739)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased IgG1 level J:103485
Adcy9tm1b(EUCOMM)Wtsi/Adcy9tm1b(EUCOMM)Wtsi
(C57BL/6N-Adcy9tm1b(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Adcyap1tm1Clw/Adcyap1tm1Clw
(B6.129S4-Adcyap1tm1Clw)
abnormal regulatory T cell physiology J:194151
abnormal T cell activation J:194151
increased microglial cell activation J:194151
increased T-helper 17 cell number J:194151
Adcyap1r1tm1Bbt/Adcyap1r1tm1Bbt
(involves: 129 * C57BL/6J)
increased susceptibility to bacterial infection J:73990
Add2tm1Feb/Add2tm1Feb
(B6.129-Add2tm1Feb)
increased spleen weight J:63047
Add2tm1Llp/Add2tm1Llp
(involves: 129S4/SvJae * C57BL/6J)
enlarged spleen J:71029
increased spleen iron level J:71029
Adgbem1(IMPC)Mbp/Adgb+
(C57BL/6NCrl-Adgbem1(IMPC)Mbp/Mmucd)
increased eosinophil cell number J:211773
Adgrb1tm2a(EUCOMM)Wtsi/Adgrb1+
(C57BL/6N-Adgrb1tm2a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Adgrd1tm1b(EUCOMM)Wtsi/Adgrd1tm1b(EUCOMM)Wtsi
(C57BL/6N-Adgrd1tm1b(EUCOMM)Wtsi/Wtsi)
increased anti-nuclear antigen antibody level J:211773
Adgre1m1Btlr/Adgre1m1Btlr
(C57BL/6J-Adgre1m1Btlr)
immune system phenotype J:135219
Adgre1m2Btlr/Adgre1m2Btlr
(C57BL/6J-Adgre1m2Btlr)
abnormal macrophage physiology J:195410
decreased macrophage cell number J:195410
Adgre1m3Btlr/Adgre1m3Btlr
(C57BL/6J-Adgre1m3Btlr)
abnormal macrophage physiology J:234244
decreased macrophage cell number J:234244
Adgre1M4Btlr/Adgre1+
(C57BL/6J-Adgre1M4Btlr)
decreased macrophage cell number J:255001
Adgre1M4Btlr/Adgre1M4Btlr
(C57BL/6J-Adgre1M4Btlr)
decreased macrophage cell number J:255001
Adgre1tm1Stst/Adgre1tm1Stst
(B6.129S1-Emr1tm1Stst)
abnormal immune tolerance J:99213
abnormal regulatory T cell physiology J:99213
Adgre5tm1.1Joha/Adgre5tm1.1Joha
(involves: 129P2/OlaHsd * C57BL/6J * FVB/N)
immune system phenotype J:140713
increased granulocyte number J:140713
Adgre5tm1Kake/Adgre5tm1Kake
(B6.129S6-Adgre5tm1Kake)
decreased susceptibility to bacterial infection J:118705
decreased susceptibility to bacterial infection induced morbidity/mortality J:118705
immune system phenotype J:118705
increased granulocyte number J:118705
Adgrf5tm1.2Bstc/Adgrf5tm1.2Bstc
(involves: 129S4/SvJae * C57BL/6J)
increased macrophage derived foam cell number J:196943
Adgrf5tm1.2Jpbs/Adgrf5tm1.2Jpbs
(BALB/c-Adgrf5tm1.2Jpbs)
abnormal alveolar macrophage morphology J:221769
Adgrf5tm1b(KOMP)Wtsi/Adgrf5tm1b(KOMP)Wtsi
(C57BL/6N-Adgrf5tm1b(KOMP)Wtsi/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
Adgrf5tm1Shiro/Adgrf5tm1Shiro
(B6.Cg-Adgrf5tm1Shiro)
abnormal alveolar macrophage morphology J:204701
increased macrophage cell number J:204701
Adgrg3tm1Fwa/Adgrg3tm1Fwa
(129S4/SvJae-Adgrg3tm1Fwa)
immune system phenotype J:62512
Adgrg3tm1Zgwg/Adgrg3tm1Zgwg
(involves: 129 * C57BL/6)
abnormal B cell morphology J:222670
abnormal IgG1 level J:222670
abnormal IgG2 level J:222670
abnormal IgG level J:222670
abnormal immune system morphology J:222670
abnormal immune system physiology J:222670
abnormal immunoglobulin level J:222670
abnormal spleen B cell follicle morphology J:222670
abnormal spleen B cell follicle shape J:222670
abnormal spleen marginal zone morphology J:222670
abnormal spleen morphology J:222670
decreased follicular B cell number J:222670
decreased IgA level J:222670
decreased IgG1 level J:222670
decreased IgG2b level J:222670
decreased IgG3 level J:222670
decreased IgM level J:222670
decreased mature B cell number J:222670
decreased transitional stage T1 B cell number J:222670
immune system phenotype J:222670
increased B cell apoptosis J:222670
increased IgG1 level J:222670
increased IgG2a level J:222670
increased marginal zone B cell number J:222670
increased transitional stage T2 B cell number J:222670
Adgrl4em1(IMPC)Mbp/Adgrl4em1(IMPC)Mbp
(C57BL/6N-Adgrl4em1(IMPC)Mbp/MbpMmucd)
increased neutrophil cell number J:211773
Adh5tm1.1Llli/Adh5tm1.1Llli
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(B6.Cg-Adh5tm1.1Llli Speer6-ps1Tg(Alb-cre)21Mgn)
increased susceptibility to bacterial infection induced morbidity/mortality J:173666
Adh5tm1b(EUCOMM)Wtsi/Adh5tm1b(EUCOMM)Wtsi
(C57BL/6N-Adh5tm1b(EUCOMM)Wtsi/H)
decreased spleen weight J:211773
Adh5tm1Stam/Adh5tm1Stam
(B6.129-Adh5tm1Stam)
increased susceptibility to bacterial infection J:88337
increased susceptibility to bacterial infection induced morbidity/mortality J:88337
Adip1LG/J/?
Capn10tm1Chev/Capn10+

((B6.129-Capn10tm1Chev x LG/J)F1)
increased spleen weight J:153477
Adipoqtm1Chan/Adipoq+
(B6.129-Adipoqtm1Chan)
abnormal leukocyte physiology J:122020
increased leukocyte cell number J:122020
Adipoqtm1Chan/Adipoqtm1Chan
(B6.129-Adipoqtm1Chan)
abnormal leukocyte physiology J:122020
increased leukocyte cell number J:122020
Adipoqtm1Ish/Adipoqtm1Ish
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal osteoclast morphology J:199264
Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
(C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Adipor2tm1b(EUCOMM)Hmgu/Adipor2tm1b(EUCOMM)Hmgu
(C57BL/6N-Adipor2tm1b(EUCOMM)Hmgu/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Adkem1(IMPC)Ccpcz/Adk+
(C57BL/6N-Adkem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Adm2em1Zhan/Adm2em1Zhan
(Not Specified)
increased inflammatory response J:266495
increased Ly6C high monocyte number J:266495
increased susceptibility to infection J:266495
liver inflammation J:266495
Admtm1Kmca/Admtm1Kmca
(B6.129P2-Admtm1Kmca)
increased uterine NK cell number J:201446
Admtm1Tfjt/Adm+
(involves: C57BL/6 * CBA)
blood vessel inflammation J:102946
Admtm1Unc/Admtm1Unc
(involves: 129S6/SvEvTac)
decreased uterine NK cell number J:201446
Admtm1Unc/Admtm1Unc
(129S6/SvEvTac-Admtm1Unc)
abnormal lymph organ development J:130930
Adnp2em3(IMPC)Tcp/Adnp2+
(C57BL/6NCrl-Adnp2em3(IMPC)Tcp/Tcp)
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
small spleen J:211773
Adora2aem1(IMPC)H/Adora2aem1(IMPC)H
(C57BL/6N-Adora2aem1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Adora2atm1Map/Adora2atm1Map
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased interleukin-10 secretion J:147023
Adora2btm1.1Msit/Adora2btm1.1Msit
(either: (involves: C57BL/6) or (involves: C57BL/6 * CD-1 * ICR))
abnormal macrophage physiology J:169155
increased interleukin-6 secretion J:169155
increased tumor necrosis factor secretion J:169155
Adora2btm1Dgen/Adora2btm1Dgen
(B6.129P2-Adora2btm1Dgen)
abnormal dendritic cell physiology J:138722
decreased interleukin-10 secretion J:147023
Adora2btm1Kra/Adora2btm1Kra
(involves: 129 * C57BL/6J)
abnormal cytokine level J:111715
abnormal inflammatory response J:111715
abnormal interleukin level J:111715
abnormal leukocyte adhesion J:111715
abnormal leukocyte migration J:111715
abnormal tumor necrosis factor level J:111715
decreased interleukin-10 secretion J:111715
enhanced leukocyte tethering or rolling J:111715
increased circulating interleukin-6 level J:111715
Adora2btm1Till/Adora2btm1Till
(B6.129P2-Adora2btm1Till)
abnormal cellular extravasation J:125297
increased interleukin-6 secretion J:125297
increased susceptibility to type I hypersensitivity reaction J:125297
Adora3tm1(ADORA3)Msth/Adora3tm1(ADORA3)Msth
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal mast cell physiology J:104494
decreased mast cell degranulation J:104494
Adora3tm1Jbsn/Adora3tm1Jbsn
(either: (involves: 129P2/OlaHsd * C57BL/6 * DBA/2) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal mast cell physiology J:60293
decreased tumor necrosis factor secretion J:60293
Adora3tm1Jbsn/Adora3tm1Jbsn
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased acute inflammation J:120442
Adora3tm1Jbsn/Adora3tm1Jbsn
(B6.129P2-Adora3tm1Jbsn)
abnormal mast cell degranulation J:123463
impaired neutrophil recruitment J:123463
Adprhtm1Jlms/Adprhtm1Jlms
(involves: 129X1/SvJ * C57BL/6J)
increased susceptibility to infection J:123619
Adrb2em1(IMPC)Mbp/Adrb2em1(IMPC)Mbp
(C57BL/6N-Adrb2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Adrb2tm1Bkk/Adrb2+
(involves: 129S1/Sv * 129X1/SvJ)
abnormal osteoclast differentiation J:97566
Adrb2tm1Bkk/Adrb2tm1Bkk
(involves: 129S1/Sv * 129X1/SvJ)
abnormal osteoclast differentiation J:97566
abnormal osteoclast morphology J:97566
abnormal osteoclast physiology J:97566
Adrb2tm1Bkk/Adrb2tm1Bkk
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2 * FVB/N)
increased tumor necrosis factor secretion J:204379
Adrm1Gt(OST128063)Lex/Adrm1Gt(OST128063)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal single-positive T cell number J:166694
enlarged thymus J:166694
immune system phenotype J:166694
increased CD4-positive, alpha-beta T cell number J:166694
increased CD8-positive, alpha-beta T cell number J:166694
thymus hyperplasia J:166694
Ads1NZB/Ads1NZB
(involves: NZB * NZW)
increased anti-double stranded DNA antibody level J:7239, J:7111
increased susceptibility to autoimmune disorder J:7111
Ads1NZB/Ads1NZW
(involves: NZB * NZW)
increased anti-double stranded DNA antibody level J:7111
increased susceptibility to autoimmune disorder J:7111
Ads2NZB/Ads2NZB
(involves: NZB * NZW)
increased anti-double stranded DNA antibody level J:7111
increased susceptibility to autoimmune disorder J:7111
Ads2NZB/Ads2NZW
(involves: NZB * NZW)
increased anti-double stranded DNA antibody level J:7111
increased susceptibility to autoimmune disorder J:7111
Ads3NZB/Ads3NZW
(involves: NZB * NZW)
abnormal immunoglobulin level J:7111
increased susceptibility to autoimmune disorder J:7111
Ads3NZW/Ads3NZW
(involves: NZB * NZW)
abnormal immunoglobulin level J:7111
increased anti-double stranded DNA antibody level J:7239
increased susceptibility to autoimmune disorder J:7111
Ads4NZB/Ads4NZB
(involves: NZB * NZW)
decreased anti-double stranded DNA antibody level J:11074
Ads4NZB/Ads4NZW
(involves: NZB * NZW)
abnormal immunoglobulin level J:7111
increased susceptibility to autoimmune disorder J:7111
Ads4NZW/Ads4NZW
(involves: NZB * NZW)
abnormal immunoglobulin level J:7111
increased susceptibility to autoimmune disorder J:7111
Adss2tm1b(EUCOMM)Wtsi/Adss2+
(C57BL/6N-Adss2tm1b(EUCOMM)Wtsi/Bay)
decreased eosinophil cell number J:211773
Adtrptm1.1Clu/Adtrptm1.1Clu
(involves: 129S4/SvJaeSor * C57BL/6)
increased inflammatory response J:295059
increased mast cell number J:295059
Aec1NOD/Uf/Aec1NOD/Uf
Aec2NOD/Uf/Aec2NOD/Uf

(B6.NOD-Aec2NOD/Uf Aec1NOD/Uf)
increased anti-nuclear antigen antibody level J:129282
increased susceptibility to autoimmune disorder J:128900
lacrimal gland inflammation J:129282
salivary gland inflammation J:129282
Aem1C57BL/6/Aem1NZB
(involves: C57BL/6 * NZB)
decreased autoantibody level J:7191
Aem2C57BL/6/Aem2C57BL/6
(involves: C57BL/6 * NZB)
decreased autoantibody level J:59427
Aem2C57BL/6/Aem2NZB
(involves: C57BL/6 * NZB)
decreased autoantibody level J:59427
Aem2C57BL/6/Aem2NZB
Aem3C57BL/6/Aem3NZB

(involves: C57BL/6 * NZB)
decreased autoantibody level J:59427
Aem3C57BL/6/?
(involves: C57BL/6 * NZB)
abnormal immune system physiology J:59427
Afap1l2tm1b(KOMP)Wtsi/Afap1l2tm1b(KOMP)Wtsi
(C57BL/6N-Afap1l2tm1b(KOMP)Wtsi/Ucd)
abnormal spleen morphology J:211773
increased neutrophil cell number J:211773
Afdnem1(IMPC)Mbp/Afdn+
(C57BL/6N-Afdnem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
decreased spleen weight J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
small spleen J:211773
Aff1Rob/Aff1+
(involves: BALB/cAnNCrl * C3H/HeN)
abnormal double-negative T cell morphology J:82265
decreased thymus weight J:82265
thymus hypoplasia J:82265
Aff1tm1Cim/Aff1tm1Cim
(involves: 129P2/OlaHsd * BALB/c)
abnormal immune system cell morphology J:63253
abnormal immune system organ morphology J:63253
abnormal T cell differentiation J:63253
decreased B cell number J:63253
decreased double-positive T cell number J:63253
decreased mature B cell number J:63253
decreased pre-B cell number J:63253
decreased single-positive T cell number J:63253
thymus hypoplasia J:63253
Afg3l1tm1.1Arte/Afg3l1tm1.1Arte
Afg3l2tm1Arte/Afg3l2tm1Arte
Tg(Plp1-cre/ERT)3Pop/0

(involves: C57BL/6J * C57BL/6N)
microgliosis J:237410
Afg3l2tm1Arte/Afg3l2tm1Arte
Tg(Pcp2-cre)2Mpin/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
microgliosis J:193564
Agbl1em1Zfa/Agbl1em1Zfa
(Not Specified)
immune system phenotype J:231311
Agbl2em1Zfa/Agbl2em1Zfa
(Not Specified)
immune system phenotype J:231311
Agbl3em1Zfa/Agbl3em1Zfa
(Not Specified)
immune system phenotype J:231311
Agbl4em1(IMPC)Mbp/Agbl4em1(IMPC)Mbp
(C57BL/6NCrl-Agbl4em1(IMPC)Mbp/Mmucd)
increased monocyte cell number J:211773
Agbl4Tn(pb-Act-RFP)1.080115015-HRAZhu/Agbl4Tn(pb-Act-RFP)1.080115015-HRAZhu
(involves: FVB/N)
abnormal spleen morphology J:233744
increased spleen weight J:233744
increased susceptibility to Herpesvirales infection J:231311
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:231311
increased susceptibility to Poxviridae infection J:231311
increased susceptibility to Poxviridae infection induced morbidity/mortality J:231311
Agbl5em1Zfa/Agbl5em1Zfa
(Not Specified)
increased susceptibility to Herpesvirales infection J:231311
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:231311
increased susceptibility to Poxviridae infection J:231311
increased susceptibility to Poxviridae infection induced morbidity/mortality J:231311
Agertm1.1Arnd/Agertm1.1Arnd
(B6.129P2-Agertm1.1Arnd)
decreased circulating interleukin-6 level J:104998
decreased osteoclast cell number J:104998
Agertm1.1Arnd/Agertm1.1Arnd
(involves: 129P2/OlaHsd)
abnormal immune system physiology J:113376
Agertm1Arnd/Ager+
Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased dendritic cell number J:194800
decreased plasmacytoid dendritic cell number J:194800
Agkem1Qiz/Agkem1Qiz
(involves: C57BL/6 * DBA/2)
abnormal CD8-positive, alpha beta T cell morphology J:282052
abnormal CD8-positive, alpha-beta T cell physiology J:282052
decreased effector memory CD8-positive, alpha-beta T cell number J:282052
Agktm1.1Smoc/Agktm1.1Smoc
(Not Specified)
decreased effector memory CD8-positive, alpha-beta T cell number J:282052
immune system phenotype J:282052
Aglna/?
(C57BL/6-Aglna/Anu)
abnormal spleen marginal zone morphology J:169366
increased activated T cell number J:169366
Agnm1MRL/MpJ/Agnm1MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
glomerulonephritis J:97786
increased susceptibility to systemic lupus erythematosus J:97786
Agnm2C3H/HeJ/Agnm2MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
glomerulonephritis J:97786
increased susceptibility to systemic lupus erythematosus J:97786
Agnm2MRL/MpJ/Agnm2MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
glomerulonephritis J:97786
increased susceptibility to systemic lupus erythematosus J:97786
Agnm3C3H/HeJ/Agnm3MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
glomerulonephritis J:97786
increased susceptibility to systemic lupus erythematosus J:97786
Agnm3MRL/MpJ/Agnm3MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
glomerulonephritis J:97786
increased susceptibility to systemic lupus erythematosus J:97786
Ago2tm1.1Tara/Ago2tm1.1Tara
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA)
enlarged spleen J:165967
Agp1NZB/Agp1NZB
(involves: NZB * NZW)
increased susceptibility to type III hypersensitivity reaction J:6920
Agp1NZB/Agp1NZW
(involves: NZB * NZW)
increased susceptibility to type III hypersensitivity reaction J:6920
Agp2NZB/Agp2NZW
(involves: NZB * NZW)
increased susceptibility to type III hypersensitivity reaction J:6920
Agp2NZW/Agp2NZW
(involves: NZB * NZW)
increased susceptibility to type III hypersensitivity reaction J:6920
Agpat2Gt(OST438470)Lex/Agpat2Gt(OST438470)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
brown adipose tissue inflammation J:186035
granulomatous inflammation J:186035
liver inflammation J:186035
Agpat2tm1Garg/Agpat2tm1Garg
(involves: 129S6/SvEvTac)
increased spleen weight J:146649
Agpat5em1(IMPC)Ccpcz/Agpat5em1(IMPC)Ccpcz
(C57BL/6NCrl-Agpat5em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased NK cell number J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Agr2tm1.1Lpkn/Agr2tm1.1Lpkn
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+

(involves: 129 * 129S6/SvEvTac * C57BL/6)
colitis J:156704
Agr2tm1.2Erle/Agr2tm1.2Erle
(involves: 129S4/SvJae * FVB/N)
increased mast cell number J:148339
increased susceptibility to induced colitis J:148339
Agr2tm1.2Lpkn/Agr2tm1.2Lpkn
(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
abnormal Peyer's patch follicle morphology J:156704
colitis J:156704
ileum inflammation J:156704
Agttm1Afu/Agttm1Afu
(involves: C57BL/6 * CBA)
tubulointerstitial nephritis J:46506
Agttm1Unc/Agttm1Unc
(involves: 129P2/OlaHsd * C57BL/6J)
tubulointerstitial nephritis J:24156
Agtpbp1atms/Agtpbp1atms
(MRL/Mp-Agtpbp1atms Faslpr)
decreased spleen weight J:103944
Agtpbp1atms/Agtpbp1atms
(MRL/Mp-Agtpbp1atms)
abnormal lymphocyte cell number J:103944
abnormal spleen morphology J:103944
abnormal T cell differentiation J:103944
abnormal T cell physiology J:103944
abnormal T cell subpopulation ratio J:103944
decreased B cell number J:103944
decreased spleen weight J:103944
increased CD4-positive, alpha-beta T cell number J:103944
increased CD8-positive, alpha-beta T cell number J:103944
spleen hypoplasia J:103944
Agtpbp1atms/Agtpbp1atms
Faslpr/Faslpr

(MRL/Mp-Agtpbp1atms Faslpr)
enlarged lymph nodes J:103944
enlarged spleen J:103944
Agtpbp1pcd-3J/Agtpbp1pcd-3J
(involves: BALB/cByJ)
immune system phenotype J:231311
Agtr1aem1(IMPC)Rbrc/Agtr1aem1(IMPC)Rbrc
(C57BL/6NJcl-Agtr1aem1(IMPC)Rbrc/Rbrc)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Agtr1atm1Unc/Agtr1atm1Unc
Agtr1btm1Cof/Agtr1btm1Cof

(involves: 129P2/OlaHsd * C57BL/6)
kidney inflammation J:137944
Agtraptm1Tamk/Agtraptm1Tamk
(involves: C57BL/6N)
abnormal macrophage morphology J:263253
Ahcytm1b(EUCOMM)Hmgu/Ahcy+
(C57BL/6N-Ahcytm1b(EUCOMM)Hmgu/Tcp)
increased basophil cell number J:211773
Ahi1tm1Jgg/Ahi1tm1Jgg
Tg(TCF/Lef1-lacZ)34Efu/0

(involves: 129S1/Sv * 129X1/SvJ)
kidney inflammation J:154321
Ahnaktm1b(KOMP)Mbp/Ahnak+
(C57BL/6N-Ahnaktm1b(KOMP)Mbp/H)
increased large unstained cell number J:211773
increased monocyte cell number J:211773
Ahnaktm1Vtm/Ahnaktm1Vtm
(involves: 129S1/Sv * C57BL/6)
abnormal T cell activation J:131148
abnormal T-helper 1 physiology J:131148
decreased interferon-gamma secretion J:131148
decreased interleukin-2 secretion J:131148
decreased T cell proliferation J:131148
increased interleukin-4 secretion J:131148
increased susceptibility to parasitic infection J:131148
Ahrb-1/Ahrb-1
(C57BL/6J)
increased inflammatory response J:5244, J:5387
Ahrb-1/Ahrb-1
(involves: C57BL/6J * DBA/2J)
abnormal immune system physiology J:5387
Ahrtm1Bra/Ahrtm1Bra
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal cytokine secretion J:148870
abnormal Langerhans cell morphology J:148870
abnormal Langerhans cell physiology J:148870
decreased spleen germinal center size J:33827
decreased susceptibility to type IV hypersensitivity reaction J:148870
enlarged spleen J:33827
Ahrtm1Bra/Ahrtm1Bra
(B6.129-Ahrtm1Bra/J)
abnormal chemokine level J:118646
abnormal cytokine level J:118646
abnormal interleukin level J:118646
abnormal macrophage physiology J:118646
abnormal tumor necrosis factor level J:118646
increased susceptibility to bacterial infection J:118646
lung inflammation J:118646, J:100359
Ahrtm1Gonz/Ahrtm1Gonz
(involves: 129S4/SvJae * C57BL/6N)
abnormal spleen morphology J:44690
abnormal spleen red pulp morphology J:44690
bile duct inflammation J:25048
colitis J:44690
decreased spleen white pulp amount J:44690
enlarged spleen J:44690
folliculitis J:44690
heart inflammation J:44690
increased inflammatory response J:25048
small spleen J:25048
spleen hypoplasia J:25048
Ahrtm1Yfk/Ahrtm1Yfk
(involves: 129S/SvEv * C57BL/6J)
urinary bladder inflammation J:179919
Ahrtm2Bra/Ahrtm2Bra
(involves: 129/Sv * C57BL/6)
increased spleen weight J:83597
Ahrtm4.1Bra/Ahrtm4.1Bra
(involves: 129/Sv * C57BL/6)
enlarged spleen J:141978
Ahsptm1.1Mjwe/Ahsptm1.1Mjwe
(involves: 129S6/SvEvTac * C57BL/6)
enlarged spleen J:94421
Ahsptm1Mjwe/Ahsptm1Mjwe
(involves: 129S6/SvEvTac * C57BL/6)
enlarged spleen J:94421
Aia1NZB/Omr/Aia1NZB/Omr
(involves: NZB/Omr * NZC/Omr)
increased susceptibility to autoimmune hemolytic anemia J:6517
Aia1NZB/Omr/Aia1NZC/Omr
(involves: NZB/Omr * NZC/Omr)
increased susceptibility to autoimmune hemolytic anemia J:6517
Aicdaem1Jaych/Aicdaem1Jaych
(involves: C57BL/6J)
abnormal class switch recombination J:305843
abnormal lymph node cell ratio J:305843
abnormal Peyer's patch germinal center morphology J:305843
abnormal splenic cell ratio J:305843
increased IgM level J:305843
Aicdam1Btlr/Aicdam1Btlr
(C57BL/6J-Aicdam1Btlr)
abnormal humoral immune response J:265155
decreased IgE level J:265155
increased IgM level J:265155
Aicdam2Btlr/Aicdam2Btlr
(C57BL/6J-Aicdam2Btlr)
abnormal humoral immune response J:265156
decreased IgE level J:265156
increased IgM level J:265156
Aicdatm1(cre)Mnz/Aicda+
Ightm3Mnz/Igh+
Myctm37Mnz/Myc+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:145691
Aicdatm1(cre)Mnz/Aicda+
Ightm3Mnz/Igh+
Myctm39Mnz/Myc+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:145691
Aicdatm1.1Fwa/Aicdatm1.1Fwa
(involves: 129S6/SvEvTac)
abnormal class switch recombination J:209271
abnormal somatic hypermutation frequency J:209271
immune system phenotype J:209271
Aicdatm1b(EUCOMM)Hmgu/Aicdatm1b(EUCOMM)Hmgu
(C57BL/6N-Aicdatm1b(EUCOMM)Hmgu/Wtsi)
decreased follicular B cell number J:211773
decreased late germinal center B cell number J:211773
increased early germinal center B cell number J:211773
increased germinal center B cell number J:211773
increased leukocyte cell number J:211773
Aicdatm1Hon/Aicda+
(involves: C57BL/6 * CBA)
abnormal class switch recombination J:136224, J:141427
abnormal somatic hypermutation frequency J:141427
immune system phenotype J:136224
Aicdatm1Hon/Aicdatm1.1Fwa
(involves: 129S/SvEv * C57BL/6NCrlj * CBA/JNCrlj)
abnormal class switch recombination J:209271
immune system phenotype J:209271
Aicdatm1Hon/Aicdatm1Hon
(involves: C57BL/6 * CBA)
abnormal class switch recombination J:141427, J:73659, J:120658
abnormal somatic hypermutation frequency J:136224, J:141427
decreased IgA level J:169227
decreased IgG1 level J:169227, J:73659
decreased IgG2a level J:73659
decreased IgG2b level J:169227
decreased IgG3 level J:169227
decreased IgG level J:169227
increased germinal center B cell number J:169227
increased IgM level J:169227, J:73659
increased susceptibility to bacterial infection induced morbidity/mortality J:169227
Aicdatm1Hon/Aicdatm1Hon
Bcl6tm1.1Jwan/Bcl6tm1.1Jwan

(involves: 129S6/SvEvTac * C57BL/6NCrlj * CBA/JNCrlj)
abnormal somatic hypermutation frequency J:190534
Aicdatm1Hon/Aicdatm1Hon
Blmtm3Brd/Blmtm3Brd
Ightm4.1Mnz/Igh+
Trp53bp1tm1Jc/Trp53bp1tm1Jc

(involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj)
immune system phenotype J:194603
Aicdatm1Hon/Aicdatm1Hon
Exo1tm1Wed/Exo1tm1Wed
Ightm4.1Mnz/Igh+

(involves: C57BL/6 * CBA/JNCrlj * SJL)
abnormal immunoglobulin heavy chain V(D)J recombination J:194603
Aicdatm1Hon/Aicdatm1Hon
Exo1tm1Wed/Exo1tm1Wed
Ightm4.1Mnz/Igh+
Trp53bp1tm1Jc/Trp53bp1tm1Jc

(involves: 129 * C57BL/6 * CBA/JNCrlj * SJL)
abnormal immunoglobulin heavy chain V(D)J recombination J:194603
Aicdatm1Hon/Aicdatm1Hon
Ightm3Mnz/Ightm4.1Mnz
Trp53bp1tm1Jc/Trp53bp1tm1Jc

(involves: 129 * C57BL/6 * CBA)
abnormal class switch recombination J:159173
Aicdatm1Hon/Aicdatm1Hon
Ightm4.1Mnz/Igh+

(involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj)
abnormal immunoglobulin heavy chain V(D)J recombination J:194603
Aicdatm1Hon/Aicdatm1Hon
Ightm4.1Mnz/Igh+
Trp53bp1tm1Jc/Trp53bp1tm1Jc

(involves: 129 * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj)
abnormal immunoglobulin heavy chain V(D)J recombination J:194603
Aicdatm1Hon/Aicdatm1Hon
Ighmtm1.1(IGH-2)Cog/Ighm+

(involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N)
abnormal B cell physiology J:157575
Aicdatm1Hon/Aicdatm1Hon
Tg(Igkv3-5*-MYC)#Plbe/0

(involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj)
immune system phenotype J:131912
Aicdatm1Hon/Aicdatm2Mnz
(involves: C57BL/6 * CBA)
immune system phenotype J:136224
Aicdatm1Hon/Aicdatm3Mnz
(involves: C57BL/6 * CBA)
abnormal class switch recombination J:141427
abnormal somatic hypermutation frequency J:141427
Aicdatm1Hon/Aicdatm4Mnz
(involves: C57BL/6 * CBA)
abnormal class switch recombination J:141427
abnormal somatic hypermutation frequency J:141427
Aicdatm2.1Hon/Aicdatm2.1Hon
(C57BL/6-Aicdatm2.1Hon)
abnormal somatic hypermutation frequency J:169227
decreased IgG1 level J:169227
immune system phenotype J:169227
increased germinal center B cell number J:169227
increased susceptibility to bacterial infection J:169227
increased susceptibility to bacterial infection induced morbidity/mortality J:169227
Aicdatm2.1Hon/Aicdatm2.1Hon
(involves: BALB/c * C57BL/6)
increased germinal center B cell number J:169227
Aicdatm2Mnz/Aicdatm2Mnz
(B6.Cg-Aicdatm2Mnz)
immune system phenotype J:136224
Aicdatm3.1Mnz/Aicdatm3.1Mnz
(involves: C57BL/6)
abnormal class switch recombination J:147109
abnormal somatic hypermutation frequency J:147109
Aicdatm3Mnz/Aicda+
(involves: C57BL/6 * CBA)
abnormal class switch recombination J:141427
abnormal somatic hypermutation frequency J:141427
Aicdatm4.1Mnz/Aicdatm4.1Mnz
(involves: C57BL/6)
abnormal class switch recombination J:147109
abnormal somatic hypermutation frequency J:147109
Aicdatm4Mnz/Aicda+
(involves: C57BL/6 * CBA)
abnormal class switch recombination J:141427
abnormal somatic hypermutation frequency J:141427
Aif1tm1Nsib/Aif1tm1Nsib
(involves: 129S/SvEv * C57BL/6)
decreased spleen weight J:204462
decreased susceptibility to induced arthritis J:204462
Aif1ltm1b(EUCOMM)Wtsi/Aif1ltm1b(EUCOMM)Wtsi
(C57BL/6N-Aif1ltm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
small thymus J:211773
Aim2em1(IMPC)Ccpcz/Aim2em1(IMPC)Ccpcz
(C57BL/6N-Aim2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Aim2Gt(CSG445)Byg/Aim2Gt(CSG445)Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:158969
decreased circulating interleukin-18 level J:158969
decreased interleukin-1 beta secretion J:158969
decreased interleukin-18 secretion J:158969
decreased NK cell number J:158969
increased interferon-beta secretion J:158969
increased susceptibility to bacterial infection J:158969
increased susceptibility to Herpesvirales infection J:158969
increased susceptibility to Poxviridae infection J:158969
Aim2Gt(CSG445)Byg/Aim2Gt(CSG445)Byg
(involves: 129P2/OlaHsd)
immune system phenotype J:173245
Aim2Gt(CSG445)Byg/Aim2Gt(CSG445)Byg
(B6.129P2-Aim2Gt(CSG445)Byg/J)
abnormal interferon secretion J:234263
decreased interleukin-1 beta secretion J:234263
decreased macrophage apoptosis J:234263
Aim2tm1.1Vmd/Aim2tm1.1Vmd
(C57BL/6-Aim2tm1.1Vmd)
abnormal cytokine secretion J:160545
abnormal macrophage physiology J:160545
decreased interleukin-1 beta secretion J:160545
decreased interleukin-18 secretion J:160545
increased interferon-beta secretion J:160545
increased susceptibility to bacterial infection J:160545
increased tumor necrosis factor secretion J:160545
Aim2tm1.2Arte/Aim2tm1.2Arte
Dnase2atm1Osa/Dnase2atm1Osa
Ifnar1tm1Agt/Ifnar1tm1Agt

(involves: 129 * BALB/c * C57BL/6 * C57BL/6J)
abnormal spleen morphology J:238323
enlarged spleen J:238323
increased autoantibody level J:238323
increased circulating interleukin-10 level J:238323
increased circulating tumor necrosis factor level J:238323
increased spleen weight J:238323
rheumatoid arthritis J:238323
Aim2tm1Ktak/Aim2tm1Ktak
(involves: 129S4/SvJae * C57BL/6)
decreased circulating interleukin-18 level J:188013
decreased interferon-gamma secretion J:188013
decreased interleukin-1 beta secretion J:188013
decreased interleukin-18 secretion J:188013
increased susceptibility to bacterial infection J:188013
increased susceptibility to bacterial infection induced morbidity/mortality J:188013
Aimp1em1(IMPC)Tcp/Aimp1em1(IMPC)Tcp
(C57BL/6NCrl-Aimp1em1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
Aimp1Gt(OST58507)Lex/Aimp1Gt(OST58507)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
decreased inflammatory response J:95974
Airetm1.1(cre)Ghr/Airetm1.1(cre)Ghr
(Not Specified)
decreased dendritic cell number J:176844
decreased regulatory T cell number J:176844
increased dendritic cell number J:176844
Airetm1.1(NCOM)Mfgc/Airetm1.1(NCOM)Mfgc
(C57BL/6N-Airetm1.1(NCOM)Mfgc/Tcp)
increased monocyte cell number J:211773
Airetm1.1Doi/Airetm1.1Doi
(involves: 129S2/SvPas * C57BL/6)
abnormal thymus medulla morphology J:83422
increased autoantibody level J:119475
increased susceptibility to autoimmune disorder J:83422
increased T cell number J:83422
stomach inflammation J:119475
Airetm1.1Doi/Airetm1.1Doi
(B6.129S2-Airetm1.1Doi/Doi)
increased autoantibody level J:107432
increased incidence of corneal inflammation J:107432
lung inflammation J:107432
salivary gland inflammation J:107432
stomach inflammation J:107432
Airetm1.1Doi/Airetm1.1Doi
(NOD.129S2(B6)-Airetm1.1Doi/Doi)
increased autoantibody level J:107432
increased incidence of corneal inflammation J:107432
liver inflammation J:107432
lung inflammation J:107432
ovary inflammation J:107432
pancreas inflammation J:107432
prostate gland inflammation J:107432
salivary gland inflammation J:107432
stomach inflammation J:107432
thyroid gland inflammation J:107432
Airetm1.1Doi/Airetm1.1Doi
(C.129S2-Airetm1.1Doi/Doi)
increased autoantibody level J:107432
increased incidence of corneal inflammation J:107432
liver inflammation J:107432
lung inflammation J:107432
ovary inflammation J:107432
prostate gland inflammation J:107432
salivary gland inflammation J:107432
stomach inflammation J:107432
Airetm1.1Doi/Airetm1.1Doi
(SJL.129S2-Airetm1.1Doi/Doi)
increased autoantibody level J:107432
liver inflammation J:107432
lung inflammation J:107432
ovary inflammation J:107432
pancreas inflammation J:107432
prostate gland inflammation J:107432
salivary gland inflammation J:107432
stomach inflammation J:107432
Airetm1.1Doi/Airetm1.1Doi
(involves: 129S2/SvPas * C57BL/6 * NOD)
liver inflammation J:107432
lung inflammation J:107432
pancreas inflammation J:107432
salivary gland inflammation J:107432
stomach inflammation J:107432
Airetm1.1Doi/Airetm1.1Doi
(NOD.129S2-Airetm1.1Doi)
abnormal CD4-positive, alpha-beta T cell physiology J:135154
chronic pancreas inflammation J:135154
insulitis J:135154
lacrimal gland inflammation J:135154
lung inflammation J:135154
salivary gland inflammation J:135154
stomach inflammation J:135154
thyroid gland inflammation J:135154
uveitis J:135154
Airetm1.1Doi/Airetm1.1Doi
H2b/H2b

(NOD.Cg-Airetm1.1Doi H2b/Doi)
stomach inflammation J:107432
Airetm1.1Doi/Airetm1.1Doi
Idd3C57BL/6/Idd3C57BL/6
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ

(NOD.Cg-Idd3C57BL/6 Idd5C57BL/10SnJ Airetm1.1Doi/Doi)
stomach inflammation J:107432
Airetm1.1Doi/Airetm1.1Doi
Il1r1tm1Imx/Il1r1+

(involves: 129S2/SvPas * 129S7/SvEvBrd * NOD)
keratoconjunctivitis J:163691
lacrimal gland inflammation J:163691
Airetm1.1Doi/Airetm1.1Doi
Il1r1tm1Imx/Il1r1tm1Imx

(involves: 129S2/SvPas * 129S7/SvEvBrd * NOD)
keratoconjunctivitis J:163691
lacrimal gland inflammation J:163691
Airetm1.1Doi/Airetm1.1Doi
Tg(Ins2-TFRC/OVA)296Wehi/0
Tg(TcraTcrb)425Cbn/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:135154
decreased CD4-positive, alpha-beta T cell number J:135154
Airetm1Mand/Aire+
(involves: 129P2/OlaHsd * C57BL/6)
lacrimal gland inflammation J:135154
salivary gland inflammation J:135154
Airetm1Mand/Aire+
(NOD.129P2-Airetm1Mand)
abnormal CD4-positive, alpha-beta T cell physiology J:135154, J:188686
abnormal chemokine level J:188686
chronic pancreas inflammation J:135154
CNS inflammation J:135154
increased autoantibody level J:188686
increased CXCL10 level J:188686
increased inflammatory response J:188686
increased susceptibility to autoimmune diabetes J:135154, J:188686
insulitis J:135154
lacrimal gland inflammation J:135154
salivary gland inflammation J:135154
thyroid gland inflammation J:135154
Airetm1Mand/Aire+
Tg(Ins2-TFRC/OVA)296Wehi/0
Tg(TcraTcrb)425Cbn/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:135154
Airetm1Mand/Airetm1.1Doi
(NOD.129-Airetm1Mand/Airetm1.1Doi)
abnormal CD4-positive, alpha-beta T cell physiology J:135154
chronic pancreas inflammation J:135154
insulitis J:135154
lacrimal gland inflammation J:135154
lung inflammation J:135154
salivary gland inflammation J:135154
stomach inflammation J:135154
thyroid gland inflammation J:135154
uveitis J:135154
Airetm1Mand/Airetm1Mand
(involves: 129P2/OlaHsd * C57BL/6)
eye inflammation J:135154
lacrimal gland inflammation J:135154
salivary gland inflammation J:135154
Airetm1Mmat/Airetm1Mmat
(involves: C57BL/6 * CBA)
autoimmune response J:96580
lacrimal gland inflammation J:96580
pancreas inflammation J:96580
parotid gland inflammation J:96580
stomach inflammation J:96580
submandibular gland inflammation J:96580
Airetm1Mmat/Airetm1Mmat
(C.Cg-Airetm1Mmat)
increased autoantibody level J:96580
stomach inflammation J:96580
Airetm1Mmat/Airetm1Mmat
(B6.Cg-Airetm1Mmat)
autoimmune response J:96580
salivary gland inflammation J:96580
Airetm1Mmat/Airetm2Mmat
(involves: C57BL/6 * CBA)
abnormal thymus morphology J:141379
autoimmune response J:141379
Airetm1Mmat/Airetm2Mmat
Tg(TcraTcrb)425Cbn/?

(involves: BALB/c * C57BL/6 * CBA)
abnormal thymus morphology J:141379
immune system phenotype J:141379
Airetm1Pltn/Airetm1Pltn
(involves: 129S4/SvJae * C57BL/6)
abnormal T cell morphology J:77873
increased autoantibody level J:77873
increased T cell proliferation J:77873
liver inflammation J:77873
thymus atrophy J:77873
Airetm1Pltn/Airetm1Pltn
(B6.129S4-Airetm1Pltn)
abnormal metallophilic macrophage morphology J:115076
abnormal myelopoiesis J:115076
abnormal spleen marginal zone morphology J:115076
decreased follicular B cell number J:115076
enlarged spleen J:115076
immune system phenotype J:115076
increased B cell number J:115076
increased marginal zone B cell number J:115076
increased monocyte cell number J:115076
increased spleen weight J:115076
liver inflammation J:115076
Airetm1Ptsn/Airetm1Ptsn
(C57BL/6-Airetm1Ptsn)
abnormal T cell activation J:145910
abnormal thymus medulla morphology J:145910
increased autoantibody level J:145910
parotid gland inflammation J:145910
sublingual gland inflammation J:145910
uveitis J:145910
vitreous body inflammation J:145910
Airetm1Ptsn/Airetm1Ptsn
(C.B6-Airetm1Ptsn)
abnormal adaptive immunity J:174653
abnormal cytokine level J:174653
abnormal regulatory T cell physiology J:174653
abnormal T-helper 1 physiology J:174653
abnormal T-helper 17 cell physiology J:174653
decreased susceptibility to fungal infection J:174653
increased interleukin-6 secretion J:174653
increased interleukin-12 secretion J:174653
increased interleukin-23 secretion J:174653
increased susceptibility to autoimmune disorder J:174653
increased susceptibility to fungal infection J:174653
increased tumor necrosis factor secretion J:174653
stomach inflammation J:174653
Airetm2Mmat/Airetm2Mmat
(involves: C57BL/6 * CBA)
abnormal thymus morphology J:141379
abnormal thymus physiology J:141379
absent Hassall's corpuscle J:141379
autoimmune response J:141379
Ajubaem1(IMPC)H/Ajubaem1(IMPC)H
(C57BL/6N-Ajubaem1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased large unstained cell number J:211773
increased neutrophil cell number J:211773
Ak7em1(IMPC)Ccpcz/Ak7+
(C57BL/6NCrl-Ak7em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Ak7Gt(OST434404)Lex/Ak7Gt(OST434404)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
rhinosinusitis J:185566
Ak7Tg(tetO-Hmox1)67Sami/Ak7Tg(tetO-Hmox1)67Sami
(FVB/N-Ak7Tg(tetO-Hmox1)67Sami)
respiratory system inflammation J:186062
rhinitis J:186062
Akap9tm1a(KOMP)Wtsi/Akap9+
(involves: C57BL/6 * C57BL/6N)
decreased B cell number J:213427
decreased mature B cell number J:213427
increased CD4-positive, alpha-beta T cell number J:213427
increased CD8-positive, alpha-beta T cell number J:213427
increased T cell number J:213427
Akap11tm1b(EUCOMM)Hmgu/Akap11tm1b(EUCOMM)Hmgu
(B6N(Cg)-Akap11tm1b(EUCOMM)Hmgu/J)
decreased leukocyte cell number J:211773
Akap12tm1Ihg/Akap12tm1Ihg
(involves: 129S4/SvJae * C57BL/6)
increased spleen red pulp amount J:138882
liver inflammation J:138882
Akap13em1(IMPC)Mbp/Akap13em1(IMPC)Mbp
(C57BL/6N-Akap13em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Akap13tm1Segj/Akap13+
(involves: 129)
abnormal lymphocyte physiology J:111574
abnormal splenocyte physiology J:181088
decreased B cell number J:181088
decreased IgG1 level J:181088
decreased spleen B cell follicle size J:181088
decreased spleen weight J:181088
decreased splenocyte number J:181088
decreased transitional stage T2 B cell number J:181088
increased transitional stage T1 B cell number J:181088
small spleen J:181088
spleen hypoplasia J:181088
Akip1em1Cya/Akip1em1Cya
(C57BL/6N-Akip1em1Cya)
decreased susceptibility to endotoxin shock J:326919
decreased susceptibility to viral infection J:326919
Aknatm1Mak/Aknatm1Mak
(B6.129P2-Aknatm1Mak)
alveolitis J:233952
increased acute inflammation J:233952
increased neutrophil cell number J:233952
increased susceptibility to fungal infection J:233952
lung inflammation J:233952
Aknatm2Mak/Aknatm2Mak
(B6.129-Aknatm2Mak)
increased susceptibility to fungal infection J:233952
Akr1a1Gt(OST222400)Lex/Akr1a1Gt(OST222400)Lex
(B6.129S5-Akr1a1Gt(OST222400)Lex)
abnormal osteoclast physiology J:164548
increased osteoclast cell number J:164548
Akr1b8tm1Dgen/Akr1b8tm1Dgen
(Not Specified)
abnormal interferon level J:301852
abnormal interleukin level J:301852
increased susceptibility to induced colitis J:301852
Akt1tm1Nhy/Akt1tm1Nhy
(involves: 129/Sv * C57BL/6)
abnormal thymus morphology J:71404
Akt1tm1Pnt/Akt1tm1Pnt
Akt2tm1.1Mbb/Akt2tm1.1Mbb
Akt3tm1Mbb/Akt3tm1Mbb
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd)
arrested T cell differentiation J:135903
decreased double-positive T cell number J:135903
increased double-negative T cell number J:135903
increased T cell apoptosis J:135903
thymus hypoplasia J:135903
Akt1tm1Pnt/Akt1tm1Pnt
Akt2tm1.1Mbb/Akt2tm1.1Mbb
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd)
arrested T cell differentiation J:135903
decreased double-positive T cell number J:135903
increased double-negative T cell number J:135903
increased T cell apoptosis J:135903
thymus hypoplasia J:135903
Akt1tm1Pnt/Akt1tm1Pnt
Akt3tm1Mbb/Akt3tm1Mbb
Tg(Lck-cre)1Cwi/0

(Not Specified)
decreased double-positive T cell number J:135903
thymus hypoplasia J:135903
Akt2tm1.1Mbb/Akt2tm1.1Mbb
(involves: 129P2/OlaHsd)
immune system phenotype J:135903
Akt3tm1Mbb/Akt3tm1Mbb
(Not Specified)
immune system phenotype J:135903
Aktiptm1a(EUCOMM)Hmgu/Aktiptm1a(EUCOMM)Hmgu
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129S2/SvPas * C57BL/6N)
kidney inflammation J:276210
liver inflammation J:276210
lung inflammation J:276210
peritoneal inflammation J:276210
Aladem1(IMPC)Tcp/Alad+
(C57BL/6NCrl-Aladem1(IMPC)Tcp/Tcp)
enlarged thymus J:211773
Alan2B10.O20/Dem/Alan2B10.O20/Dem
(involves: B10.O20/Dem * O20/A)
abnormal immune system physiology J:67657
Alan2B10.O20/Dem/Alan2O20/A
(involves: B10.O20/Dem * O20/A)
abnormal immune system physiology J:67657
Aldh1a2tm1Dll/Aldh1a2tm1Ipc
(involves: CD-1)
athymia J:81969
thymus hypoplasia J:81969
Aldh1l2tm2e(KOMP)Wtsi/Aldh1l2tm2e(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
immune system phenotype J:299012
Aldh2tm1.1Mak/Aldh2+
(involves: 129S6/SvEvTac * C57BL/6J)
decreased leukocyte cell number J:223796
Aldh2tm1.1Mak/Aldh2tm1.1Mak
(involves: 129S6/SvEvTac * C57BL/6J)
decreased leukocyte cell number J:223796
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi
(C57BL/6N-Aldh2tm1a(EUCOMM)Wtsi/Ieg)
decreased CD4-positive, alpha-beta T cell number J:165965
decreased CD8-positive, alpha-beta T cell number J:165965
decreased T cell number J:165965
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi
Fancd2tm1Hou/Fancd2tm1Hou

(involves: 129S4/SvJae * C57BL/6J * C57BL/6N)
abnormal lymphopoiesis J:193232
abnormal spleen morphology J:188123
abnormal thymus morphology J:188123
decreased leukocyte cell number J:188123
enlarged spleen J:193232
increased CD8-positive, alpha-beta T cell number J:193232
increased double-positive T cell number J:193232
Aldh18a1tm1a(KOMP)Wtsi/Aldh18a1+
(C57BL/6N-Aldh18a1tm1a(KOMP)Wtsi/Wtsi)
skin inflammation J:232539
Aldoatm1.1(KOMP)Wtsi/Aldoa+
(C57BL/6N-Aldoatm1.1(KOMP)Wtsi/Bay)
decreased leukocyte cell number J:211773
Aldobtm1(KOMP)Vlcg/Aldobtm1(KOMP)Vlcg
(C57BL/6NTac-Aldobtm1(KOMP)Vlcg)
liver inflammation J:220330
Alg1tm1b(KOMP)Wtsi/Alg1+
(C57BL/6N-Alg1tm1b(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Alg6em1(IMPC)Tcp/Alg6+
(C57BL/6NCrl-Alg6em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Alg13tm1a(KOMP)Wtsi/Alg13tm1a(KOMP)Wtsi
(C57BL/6N-Alg13tm1a(KOMP)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Alkbh1tm1b(EUCOMM)Hmgu/Alkbh1+
(C57BL/6N-Alkbh1tm1b(EUCOMM)Hmgu/Ieg)
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
increased plasmacytoid dendritic cell number J:211773
Alms1Gt(XH152)Byg/Alms1Gt(XH152)Byg
(involves: 129P2/OlaHsd * C57BL/6J)
tubulointerstitial nephritis J:100403
Alo1/Alo1
(involves: C3H/HeJ * C57BL/6J)
abnormal lymph node morphology J:109802
enlarged lymph nodes J:109802
enlarged spleen J:109802
lymph node necrosis J:109802
Alo1/Alo1+
(involves: C3H/HeJ * C57BL/6J)
abnormal lymph node morphology J:109802
enlarged lymph nodes J:109802
enlarged spleen J:109802
lymph node necrosis J:109802
Alo2/Alo2
(involves: C3H/HeJ * C57BL/6J)
abnormal lymph node morphology J:109802
enlarged lymph nodes J:109802
enlarged spleen J:109802
lymph node necrosis J:109802
Alo2/Alo2+
(involves: C3H/HeJ * C57BL/6J)
abnormal lymph node morphology J:109802
enlarged lymph nodes J:109802
enlarged spleen J:109802
lymph node necrosis J:109802
Alox5tm1Bhk/Alox5tm1Bhk
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2))
abnormal inflammatory response J:68714
abnormal neutrophil physiology J:68714
decreased acute inflammation J:68714
decreased susceptibility to type I hypersensitivity reaction J:68714
impaired neutrophil chemotaxis J:68714
impaired neutrophil recruitment J:68714
Alox5tm1Fun/Alox5tm1Fun
(involves: 129S2/SvPas * C57BL/6)
abnormal immune system physiology J:21372
decreased inflammatory response J:21372, J:75371
immune system phenotype J:21372
small spleen J:21372
Alox5tm1Fun/Alox5tm1Fun
(B6.129S2-Alox5tm1Fun)
immune system phenotype J:89268
Alox5tm1Fun/Alox5tm1Fun
(B6.129S2-Alox5tm1Fun/J)
decreased susceptibility to experimental autoimmune uveoretinitis J:108446
Alox5aptm1Bhk/Alox5aptm1Bhk
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased susceptibility to type I hypersensitivity reaction J:39229
Alox5aptm1Bhk/Alox5aptm1Bhk
(involves: 129P2/OlaHsd * 129S/SvEv)
decreased acute inflammation J:39229
impaired neutrophil recruitment J:39229
Alox5aptm1Jdm/Alox5ap+
(DBA/1LacJ-Alox5aptm1Jdm)
decreased susceptibility to induced arthritis J:100736
immune system phenotype J:100736
Alox5aptm1Jdm/Alox5aptm1Jdm
(DBA/1LacJ-Alox5aptm1Jdm)
decreased inflammatory response J:100736
decreased susceptibility to induced arthritis J:100736
immune system phenotype J:100736
Alox8tm1a(KOMP)Wtsi/Alox8tm1a(KOMP)Wtsi
(C57BL/6N-Alox8tm1a(KOMP)Wtsi/MbpMmucd)
abnormal susceptibility to Orthomyxoviridae infection J:277623
increased interleukin-6 secretion J:277623
lung inflammation J:277623
Alox12tm1Fun/Alox12tm1Fun
(involves: 129S2/SvPas * C57BL/6)
immune system phenotype J:55741
Alox15tm1Fun/Alox15tm1Fun
(involves: 129/Sv * C57BL/6)
abnormal immune system physiology J:44778
Alox15tm1Fun/Alox15tm1Fun
(B6.129S2-Alox15tm1Fun/J)
abnormal lymph node morphology J:119405
abnormal myelopoiesis J:119405
abnormal spleen red pulp morphology J:119405
abnormal spleen white pulp morphology J:119405
decreased spleen B cell follicle number J:119405
dermatitis J:119405
increased basophil cell number J:119405
increased leukocyte cell number J:119405
increased spleen weight J:119405
intermingled spleen red and white pulp J:119405
Alox15tm1Fun/Alox15tm1Fun
(B6.129S2-Alox15tm1Fun)
immune system phenotype J:197334
Aloxe3em1(IMPC)Mbp/Aloxe3+
(C57BL/6N-Aloxe3em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
small spleen J:211773
Alpk1em1Dlka/Alpk1em1Dlka
Crb1rd8/Crb1rd8

(involves: C57BL/6N)
abnormal circulating chemokine level J:344848
immune system phenotype J:344848
increased circulating CXCL10 level J:344848
Alpltm1Jlm/Alpltm1Jlm
(either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J))
abnormal spleen morphology J:39015
abnormal thymus cortex morphology J:39015
decreased leukocyte cell number J:39015
pale spleen J:39015
small spleen J:39015
Als2tm1Jei/Als2tm1Jei
(involves: 129P2/OlaHsd * C57BL/6J)
CNS inflammation J:104446
Altretm1.1Hbgl/Altretm1.1Hbgl
Foxp3tm4(YFP/icre)Ayr/Y

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal regulatory T cell physiology J:342907
decreased regulatory T cell number J:342907
decreased T cell number J:342907
increased CD8-positive, alpha-beta T cell number J:342907
increased interleukin-17 secretion J:342907
increased memory T cell number J:342907
increased regulatory T cell apoptosis J:342907
amdA/J/amdA/J
(involves: A/J * C57BL/6J)
myocarditis J:2843, J:11025
amdDBA/2J/amdDBA/2J
(B10.D2-H8b/(57N)SnJ)
myocarditis J:11025
Amdhd1tm2b(EUCOMM)Hmgu/Amdhd1tm2b(EUCOMM)Hmgu
(C57BL/6N-Amdhd1tm2b(EUCOMM)Hmgu/BayMmucd)
increased lymphocyte cell number J:211773
Amelxem1(IMPC)Ccpcz/Y
(C57BL/6N-Amelxem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased CD4-positive NK T cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
decreased NK T cell number J:211773
enlarged thymus J:211773
small spleen J:211773
Amelxem1(IMPC)Ccpcz/Amelx+
(C57BL/6N-Amelxem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased eosinophil cell number J:211773
Amelxem1(IMPC)Ccpcz/Amelxem1(IMPC)Ccpcz
(C57BL/6N-Amelxem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Amer1tm1.2Nbar/Y
(involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL)
spleen hypoplasia J:173242
AmfrGt(IST12797A11)Tigm/AmfrGt(IST12797A11)Tigm
(C57BL/6-AmfrGt(IST12797A11)Tigm)
liver inflammation J:221247
Amhr2tm3(cre)Bhr/Amhr2+
Ptentm1Hwu/Ptentm1Hwu

(involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6)
decreased uterine NK cell number J:170203
Ampd1tm1b(KOMP)Wtsi/Ampd1+
(C57BL/6N-Ampd1tm1b(KOMP)Wtsi/Ucd)
decreased neutrophil cell number J:211773
Ampd1tm1b(KOMP)Wtsi/Ampd1tm1b(KOMP)Wtsi
(C57BL/6N-Ampd1tm1b(KOMP)Wtsi/Ucd)
enlarged lymph nodes J:211773
Ampd2tm1Tm/Ampd2tm1Tm
(involves: 129S2/SvPas)
immune system phenotype J:201211
Ampd3tm1Tm/Ampd3tm1Tm
(Not Specified)
lung inflammation J:201211
Ampd3tm1Tm/Ampd3tm1Tm
Pklrslc/Pklrslc

(involves: CBA/NSlc)
enlarged spleen J:203909
Ampd3tm2a(KOMP)Wtsi/Ampd3tm2a(KOMP)Wtsi
(B6JTyr;B6N-Ampd3tm2a(KOMP)Wtsi/Wtsi)
increased leukocyte cell number J:165965
Amtnem1(IMPC)Mbp/Amtnem1(IMPC)Mbp
(C57BL/6N-Amtnem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
anan/anan
(involves: C57BL/6 * C57BL/10Sg * C57BR/c)
increased anti-nuclear antigen antibody level J:169366
anan/anan+
(involves: C57BL/6 * C57BL/10Sg * C57BR/c)
increased anti-nuclear antigen antibody level J:169366
Anapc7em1(IMPC)J/Anapc7em1(IMPC)J
(C57BL/6NJ-Anapc7em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
anaya/anaya
(involves: C57BL/6 * C57BL/10Sg * C57BR/c)
increased anti-nuclear antigen antibody level J:169366
andra/andra
(involves: C57BL/6 * C57BL/10Sg * C57BR/c)
increased anti-nuclear antigen antibody level J:169366
anem/anem
(BALB/c-anem)
increased leukocyte cell number J:227974
Angtm1.1(KOMP)Vlcg/Angtm1.1(KOMP)Vlcg
(C57BL/6N-Angtm1.1(KOMP)Vlcg/Ucd)
increased eosinophil cell number J:211773
Angtm1Dats/Angtm1Dats
(Not Specified)
decreased leukocyte cell number J:236081
increased lymphocyte cell number J:236081
Angpt1tm1.1Seq/Angpt1tm1.1Seq
Angpt2tm1c(KOMP)Seq/Angpt2tm1c(KOMP)Seq
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/?
Tg(tetO-cre)1Jaw/0

(involves: 129 * C57BL/6NCr)
abnormal lymphatic vessel morphology J:217296
Angpt2em1(IMPC)Mbp/Angpt2+
(C57BL/6NCrl-Angpt2em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Angpt2em1(IMPC)Mbp/Angpt2em1(IMPC)Mbp
(C57BL/6NCrl-Angpt2em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
small thymus J:211773
Angpt2tm1Gdy/Angpt2tm1Gdy
(involves: 129P2/OlaHsd * C57BL/6)
abnormal lymphatic vessel morphology J:89618
Angpt2tm2(Angpt1)Gdy/Angpt2tm2(Angpt1)Gdy
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:89618
Angptl2tm1Yo/Angptl2tm1Yo
(B6.Cg-Angptl2tm1Yo)
impaired macrophage chemotaxis J:152387
Angptl3tm2b(KOMP)Wtsi/Angptl3tm2b(KOMP)Wtsi
(C57BL/6N-Angptl3tm2b(KOMP)Wtsi/Ccpcz)
enlarged lymph nodes J:211773
Angptl4Gt(OST352973)Lex/Angptl4Gt(OST352973)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal lymphatic vessel morphology J:122968
abnormal mesenteric lymph node morphology J:122968
Angptl4tm1Lex/Angptl4tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal lymphatic vessel morphology J:122968
abnormal mesenteric lymph node morphology J:122968
Ank1ity16/Ank1+
(involves: 129S1/Sv * 129X1/SvJ * DBA/2J)
increased susceptibility to bacterial infection J:199427
increased susceptibility to bacterial infection induced morbidity/mortality J:199427
Ank1ity16/Ank1ity16
(involves: 129S1/Sv * 129X1/SvJ * DBA/2J)
decreased spleen iron level J:199427
enlarged spleen J:199427
glomerulonephritis J:199427
increased leukocyte cell number J:199427
increased lymphocyte cell number J:199427
increased neutrophil cell number J:199427
increased susceptibility to bacterial infection J:199427
increased susceptibility to bacterial infection induced morbidity/mortality J:199427
Ank1M1Btlr/Ank1M1Btlr
(C57BL/6J-Ank1m1Btlr)
abnormal spleen morphology J:203831
enlarged spleen J:203831
increased spleen iron level J:203831
Ank1M1Wlst/Ank1+
(involves: 129S1/SvImJ * C3H/HeJ * C57BL/6)
enlarged spleen J:170562
Ank1M1Wlst/Ank1M1Wlst
(involves: C3H/HeJ * C57BL/6)
abnormal leukocyte cell number J:170562
Ank1M1Wlst/Ank1M1Wlst
(involves: 129S1/SvImJ * C3H/HeJ * C57BL/6)
abnormal myelopoiesis J:170562
enlarged spleen J:170562
Ank1MRI23420/Ank1+
(SJL/J-Ank1MRI23420)
abnormal spleen morphology J:187820
decreased susceptibility to parasitic infection J:187820
decreased susceptibility to parasitic infection induced morbidity/mortality J:187820
enlarged spleen J:187820
increased spleen iron level J:187820
increased spleen weight J:187820
Ank1MRI23420/Ank1MRI23420
(SJL/J-Ank1MRI23420)
enlarged spleen J:187820
increased spleen weight J:187820
Ank1nb/Ank1+
(involves: C57BL/6J * WB/Re)
decreased susceptibility to parasitic infection J:111131
Ank1nb/Ank1nb
(either: (involves: non-inbred stock) or (involves: C57BL/6) or (involves: WB/Re))
abnormal thymus development J:30699
enlarged lymph nodes J:30699
enlarged spleen J:30699
increased leukocyte cell number J:30699
Ank1nb/Ank1nb
(involves: C57BL/6J * WB/Re)
decreased susceptibility to parasitic infection J:111131
Ank1nb/Ank1nb
((WB.Cg-Ank1nb/BrkJ x B6.Cg-Ank1nb/BrkJ)F1)
enlarged spleen J:162532
Ank1Rbc2/Ank1+
(involves: 129S1/Sv * BALB/c)
decreased susceptibility to parasitic infection J:148127
Ank1Rbc2/Ank1Rbc2
(involves: 129S1/Sv * BALB/c)
enlarged spleen J:148127
Ankank/Ankank
(involves: C3HeB/FeJ * C57BL/6J * JGBF/LeJ)
arthritis J:63420
Anktm1.1Ejr/Ank+
(B6.129-Anktm1.1Ejr)
abnormal osteoclast differentiation J:168526
Anktm1.1Ejr/Anktm1.1Ejr
(B6.129-Anktm1.1Ejr)
abnormal osteoclast differentiation J:168526
Ankfy1tm1b(KOMP)Mbp/Ankfy1+
(C57BL/6N-Ankfy1tm1b(KOMP)Mbp/Tcp)
increased monocyte cell number J:211773
Ankrd2tm1Krc/Ankrd2tm1Krc
(involves: 129 * Black Swiss)
abnormal inflammatory response J:214867
Ankrd11tm1c(EUCOMM)Wtsi/Ankrd11tm1c(EUCOMM)Wtsi
E2f1Tg(Wnt1-cre)2Sor/E2f1+

(involves: C3H * C57BL/6 * C57BL/6N)
decreased osteoclast cell number J:306391
Ankrd11Yod/Ankrd11+
(involves: BALB/cAnNCrl * C3H/HeH)
decreased osteoclast cell number J:136455
Ankrd52em1(IMPC)J/Ankrd52+
(C57BL/6NJ-Ankrd52em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ano2em1(IMPC)Ccpcz/Ano2em1(IMPC)Ccpcz
(C57BL/6NCrl-Ano2em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Ano5em1Huyi/Ano5em1Huyi
(C57BL/6N-Ano5em1Huyi)
periodontium inflammation J:294237
Ano5em2Huyi/Ano5em2Huyi
(C57BL/6-Ano5em2Huyi)
abnormal osteoclast physiology J:336715
decreased osteoclast cell number J:336715
osteomyelitis J:336715
Ano6em3(IMPC)Tcp/Ano6+
(C57BL/6NCrl-Ano6em3(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Anpeptm1.1Lsha/Anpeptm1.1Lsha
(B6.Cg-Anpeptm1.1Lsha)
abnormal macrophage physiology J:163945
immune system phenotype J:163945
increased CD4-positive, alpha-beta T cell number J:163945
Anta/Anta+
(involves: C57BL/6 * C57BL/10 * C57BR/cd)
glomerulonephritis J:169366
increased anti-nuclear antigen antibody level J:169366
Anth2CBA/J/?
(involves: A/J * CBA/J)
decreased susceptibility to bacterial infection J:9501
AnthC3H/HeNCrj/AnthC3H/HeNCrj
(involves: C3H/HeNCrj * C57BL/6NCrj)
decreased susceptibility to bacterial infection J:11149
AnthC3H/HeNCrj/AnthC57BL/6NCrj
(involves: C3H/HeNCrj * C57BL/6NCrj)
decreased susceptibility to bacterial infection J:11149
Antxr1tm1.2Lepp/Antxr1tm1.2Lepp
(involves: 129 * C57BL/6)
immune system phenotype J:150952
Antxr2tm1.1Jkit/Antxr2tm1.1Jkit
(involves: 129 * C57BL/6)
lymphangiectasis J:187210
Antxr2tm1.2Lepp/Antxr2tm1.2Lepp
(involves: C57BL/6)
decreased susceptibility to bacterial infection induced morbidity/mortality J:150952
anx/anx
(B6C3Fe a/a-anx/J)
abnormal inflammatory response J:103396
decreased spleen weight J:7689
increased thymus weight J:7689
pale spleen J:7689
small spleen J:7689
anx/anx
(involves: DW/J * M. m. domesticus poschiavinus * Swiss)
abnormal spleen morphology J:13936
small spleen J:13936
Anxa1em1(IMPC)Ccpcz/Anxa1em1(IMPC)Ccpcz
(C57BL/6NCrl-Anxa1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
small spleen J:211773
Anxa1tm1Rjf/Anxa1+
(Not Specified)
increased inflammatory response J:81498
Anxa1tm1Rjf/Anxa1tm1Rjf
(Not Specified)
abnormal leukocyte physiology J:81498
impaired macrophage phagocytosis J:81498
increased inflammatory response J:81498
Anxa1tm1Rjf/Anxa1tm1Rjf
(involves: BALB/c)
increased susceptibility to induced colitis J:142735
Anxa5tm1Epo/Anxa5tm1Epo
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:117249
abnormal inflammatory response J:117249
decreased susceptibility to type IV hypersensitivity reaction J:117249
Anxa5tm1Epo/Anxa5tm1Epo
Anxa6tm1Moss/Anxa6tm1Moss

(involves: 129P2/OlaHsd * C57BL/6)
decreased dendritic cell number J:193886
increased B cell number J:193886
Anxa5tm1Epo/Anxa5tm1Epo
Anxa6tm1Moss/Anxa6tm1Moss
Col10a1tm1Ksec/Col10a1tm1Ksec

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
decreased dendritic cell number J:193886
increased B cell number J:193886
increased T-helper cell number J:193886
Anxa6tm1Moss/Anxa6tm1Moss
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:58609
Anxa7tm1Pll/Anxa7+
(Not Specified)
pancreas inflammation J:58572
Anxa8tm1Resc/Anxa8tm1Resc
Tg(Pgk1-cre)1Lni/0

(involves: 129 * C57BL/6J * BALB/c)
impaired leukocyte tethering or rolling J:225224
Aoahtm1Rsm/Aoahtm1Rsm
(involves: 129S6/SvEvTac)
abnormal humoral immune response J:90493
Aoc3tm1Salm/Aoc3tm1Salm
(involves: 129S6/SvEvTac * 129S7/SvEvBrd)
abnormal cellular extravasation J:95656
abnormal leukocyte adhesion J:95656
abnormal leukocyte migration J:95656
decreased inflammatory response J:95656
impaired leukocyte tethering or rolling J:95656
Aod1aA/J/?
(involves: A/J * C57BL/6J)
ovary inflammation J:83714
Aod1bC57BL/6J/?
(involves: A/J * C57BL/6J)
ovary inflammation J:83714
Aod3A/J/?
(A/J)
ovary inflammation J:78005
aol/aol
(involves: C3H * C57BL/6)
osteoarthritis J:115238
Ap1b1b2b1660Clo/Ap1b1b2b1660Clo
(C57BL/6J-Ap1b1b2b1660Clo)
absent spleen J:175213
spleen hypoplasia J:175213
Ap1g1tm1Schu/Ap1g1+
(either: (involves: 129P2/OlaHsd * 129X1/SvJ) or (involves: 129P2/OlaHsd * C57BL/6J))
decreased CD4-positive, alpha-beta T cell number J:53252
Ap2b1b2b2321Clo/Ap2b1b2b2321Clo
(C57BL/6J-Ap2b1b2b2321Clo)
thymus hypoplasia J:175213
Ap3b1m1Btlr/Ap3b1m1Btlr
(C57BL/6J-Ap3b1m1Btlr)
increased susceptibility to Herpesvirales infection J:132673
Ap3b1pe/Ap3b1pe
Hps1ep/Hps1ep

(involves: C3H/He * C3HeB/FeJ * C57BL/6J)
abnormal monocyte morphology J:85431
lung inflammation J:85431
Ap4e1tm1b(KOMP)Wtsi/Ap4e1tm1b(KOMP)Wtsi
(C57BL/6N-Ap4e1tm1b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Ap4e1tm1b(KOMP)Wtsi/Ap4e1tm1b(KOMP)Wtsi
(C57BL/6N-Ap4e1tm1b(KOMP)Wtsi/Ucd)
enlarged lymph nodes J:211773
Ap4e1tm1b(KOMP)Wtsi/Ap4e1tm1b(KOMP)Wtsi
(C57BL/6N-Ap4e1tm1b(KOMP)Wtsi/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Ap4m1tm1b(EUCOMM)Wtsi/Ap4m1tm1b(EUCOMM)Wtsi
(C57BL/6N-Ap4m1tm1b(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Ap5m1em1(IMPC)Mbp/Ap5m1em1(IMPC)Mbp
(C57BL/6N-Ap5m1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Apaf1tm1Mak/Apaf1tm1Mak
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1))
immune system phenotype J:49841
Apba3tm1.1Ski/Apba3tm1.1Ski
Lyz2tm1(cre)Ifo/Lyz2+

(B6.129-Apba3tm1.1Ski Lyz2tm1(cre)Ifo)
decreased susceptibility to endotoxin shock J:176742
Apba3tm1.2Ski/Apba3tm1.2Ski
(B6.129-Apba3tm1.2Ski)
abnormal macrophage physiology J:176742
decreased circulating interleukin-12 level J:176742
decreased circulating tumor necrosis factor level J:176742
decreased interleukin-12 secretion J:176742
decreased susceptibility to endotoxin shock J:176742
decreased tumor necrosis factor secretion J:176742
Apbb1ipem1(IMPC)Ccpcz/Apbb1ipem1(IMPC)Ccpcz
(C57BL/6N-Apbb1ipem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased CD8-positive, naive alpha-beta T cell number J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
ApcMin/Apc+
(C57BL/6J-ApcMin)
decreased macrophage cell number J:85142
ApcMin/Apc+
(involves: 129 * C57BL/6)
decreased NK cell number J:156864
decreased splenocyte number J:156864
decreased T cell number J:156864
ApcMin/Apc+
(C57BL/6J-ApcMin/J)
abnormal interleukin secretion J:305794
ApcMin/Apc+
Elp3tm1.1Tac/Elp3tm1.1Tac
Tg(Vil1-cre)997Gum/0

(involves: C57BL/6 * C57BL/6J * C57BL/6NTac * SJL)
immune system phenotype J:227334
ApcMin/Apc+
Esr2tm1Mma/Esr2tm1Mma

(involves: 129S2/SvPas * C57BL/6J)
colitis J:118600
ApcMin/Apc+
Mapkapk2tm1.2Gkl/Mapkapk2tm1.2Gkl

(involves: BALB/cJ * C57BL/6J)
abnormal chemokine secretion J:262876
decreased interleukin-6 secretion J:262876
ApcMin/Apc+
Tg(Rorc-EGFP)1Ebe/?

(involves: C57BL/6)
abnormal effector T cell morphology J:137020
enlarged mesenteric lymph nodes J:137020
lymph node hyperplasia J:137020
Apctm1Kk/Apctm1Kk
Tg(Lck-cre)1Cwi/?

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal T cell differentiation J:100461
arrested T cell differentiation J:100461
increased circulating tumor necrosis factor level J:128606
increased double-negative T cell number J:100461
increased mast cell number J:128606
small thymus J:100461
thymus hypoplasia J:100461
Apctm1Rak/Apc+
Smad4E6sad/Smad4+

(B6.129P2-Apctm1Rak Smad4E6sad/+ +)
enlarged spleen J:107273
Apctm1Tno/Apc+
Ptentm2Mak/Ptentm2Mak
Tg(Cyp1a1-cre/ERT)1Dwi/0

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA)
peritoneal inflammation J:143082
Apctm2.1Cip/Apc+
Atg7tm1Tchi/Atg7tm1Tchi
Tg(Vil1-cre/ERT2)23Syr/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * DBA/2)
abnormal immune system physiology J:227287
increased CD8-positive, alpha-beta T cell number J:227287
increased CD103-positive CD11b-low dendritic cell number J:227287
increased interleukin-1 beta secretion J:227287
increased interleukin-10 secretion J:227287
increased regulatory T cell number J:227287
Apctm2.1Cip/Apctm2.1Cip
Lect2tm1Ymg/Lect2tm1Ymg
Tg(Ttr-cre/Esr1*)1Vco/0

(B6.Cg-Lect2tm1Ymg Apctm2.1Cip Tg(Ttr-cre/Esr1*)1Vco)
abnormal chemokine level J:184496
abnormal neutrophil physiology J:184496
abnormal NK T cell physiology J:184496
decreased interferon-gamma secretion J:184496
increased interleukin-4 secretion J:184496
increased NK T cell number J:184496
liver inflammation J:184496
Apctm2.1Cip/Apctm2.1Cip
Tg(Ttr-cre/Esr1*)1Vco/0

(B6.Cg-Apctm2.1Cip Tg(Ttr-cre/Esr1*)1Vco)
abnormal NK T cell physiology J:184496
decreased NK T cell number J:184496
increased interferon-gamma secretion J:184496
increased interleukin-4 secretion J:184496
liver inflammation J:184496
Apctm2Rak/Apc+
Trp53tm1Brn/Trp53tm1Brn
Tg(Pdx1-cre)6Tuv/0

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL)
abnormal cytokine level J:234310
Apctm2Rak/Apctm2Rak
Tg(KRT14-cre)8Brn/0

(involves: 129/Sv * C57BL/6J * FVB/N * SJL)
abnormal Hassall's corpuscle morphology J:114152
abnormal thymus morphology J:114152
decreased thymocyte number J:114152
small thymus J:114152
Apcdd1em1(IMPC)Mbp/Apcdd1em1(IMPC)Mbp
(C57BL/6NCrl-Apcdd1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Apcstm1Mpe/Apcs+
(B6.Cg-Apcstm1Mpe)
abnormal spleen red pulp morphology J:90502
abnormal spleen white pulp morphology J:90502
glomerulonephritis J:90502
increased autoantibody level J:90502
increased spleen white pulp amount J:90502
Apcstm1Mpe/Apcstm1Mpe
(B6.Cg-Apcstm1Mpe)
abnormal spleen morphology J:90502
abnormal spleen red pulp morphology J:90502
abnormal spleen white pulp morphology J:90502
decreased susceptibility to bacterial infection J:125473
decreased susceptibility to bacterial infection induced morbidity/mortality J:125473
glomerulonephritis J:90502
increased autoantibody level J:90502
increased spleen white pulp amount J:90502
increased susceptibility to bacterial infection induced morbidity/mortality J:125473
Apcstm1Mpe/Apcstm1Mpe
(129.Cg-Apcstm1Mpe)
decreased susceptibility to bacterial infection induced morbidity/mortality J:125473
glomerulonephritis J:90502
immune system phenotype J:90502
increased susceptibility to bacterial infection induced morbidity/mortality J:125473
Apcstm1Smae/Apcstm1Smae
(involves: 129S/SvEv * C57BL/6)
decreased susceptibility to endotoxin shock J:71194
increased autoantibody level J:71194
Apex1tm1Cur/Apex1+
(involves: 129S1/Sv)
increased circulating interleukin-1 alpha level J:119957
increased circulating interleukin-10 level J:119957
Apex1tm1Ecf/Apex1+
(either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6))
heart inflammation J:70397
myocarditis J:70397
pericarditis J:70397
Apex2em1(IMPC)H/Apex2em1(IMPC)H
(C57BL/6NTac-Apex2em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Apex2tm1Yun/Y
(B6.129S-Apex2tm1Yun)
decreased B cell number J:95267
decreased leukocyte cell number J:95267
decreased splenocyte proliferation J:95267
decreased T cell number J:95267
decreased thymocyte number J:95267
thymus atrophy J:95267
AplfGt(RRF189)Byg/AplfGt(RRF189)Byg
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal class switch recombination J:168260
Apoa4tm1Bres/Apoa4tm1Bres
(B6.129S4-Apoa4tm1Bres)
increased susceptibility to induced colitis J:91357
Apobtm2Sgy/Apobtm2Sgy
Ldlrtm1Her/Ldlrtm1Her
Tg(Ins-Igf2)1Fbos/?

(involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL)
aortitis J:227165
Apobec1em1(IMPC)Ccpcz/Apobec1em1(IMPC)Ccpcz
(C57BL/6NCrl-Apobec1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
small spleen J:211773
Apobec3Gt(XN450)Byg/Apobec3Gt(XN450)Byg
(B6.Cg-Apobec3Gt(XN450)Byg)
increased susceptibility to Retroviridae infection J:118597
Apobec3Gt(XN450)Byg/Apobec3Gt(XN450)Byg
(B6.129P2-Apobec3Gt(XN450)Byg)
abnormal immunoglobulin level J:138778
increased susceptibility to Retroviridae infection J:138778
Apobec3Gt(XN450)Byg/Apobec3Gt(XN450)Byg
(129P2/OlaHsd-Apobec3Gt(XN450)Byg)
abnormal immunoglobulin level J:138778
increased susceptibility to Retroviridae infection J:138778
Apobec3Gt(XN450)Byg/Apobec3Rfv3-s
H2b/H2b

(involves: A.BY * C57BL/6)
abnormal immunoglobulin level J:138778
Apobec3Gt(XN450)Byg/Apobec3Rfv3-s
H2b/H2d

(involves: BALB/c * C57BL/6)
abnormal immunoglobulin level J:138778
increased susceptibility to Retroviridae infection J:138778
increased susceptibility to Retroviridae infection induced morbidity/mortality J:138778
Apobec3Rfv3-r/Apobec3+
((B10.A x A)F1)
decreased susceptibility to Retroviridae infection J:6147
immune system phenotype J:41946, J:6261, J:6147
Apoc4tm1.1(KOMP)Mbp/Apoc4tm1.1(KOMP)Mbp
(C57BL/6N-Apoc4tm1.1(KOMP)Mbp/Ieg)
increased leukocyte cell number J:211773
Apoetm1.1Mae/Apoetm1.1Mae
Tg(Fabp4-cre)1Rev/0

(B6.Cg-Apoetm1.1Mae Tg(Fabp4-cre)1Rev)
decreased macrophage cell number J:219838
increased macrophage cell number J:219838
Apoetm1Bres/Apoetm1Bres
Bcl2tm1Irt/Bcl2tm1Irt
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
increased macrophage apoptosis J:144243
Apoetm1Bres/Apoetm1Bres
Cx3cr1tm1Ifc/Cx3cr1tm1Ifc

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
impaired macrophage chemotaxis J:81822
Apoetm1Bres/Apoetm1Bres
Mapk9tm1Flv/Mapk9tm1Flv

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
abnormal macrophage morphology J:94044
abnormal macrophage physiology J:94044
increased macrophage derived foam cell number J:94044
Apoetm1Khw/Apoetm1Khw
Tg(Mx1-cre)29-4Her/0

(B6.Cg-Apoetm1Khw Tg(Mx1-cre)29-4Her)
immune system phenotype J:196923
Apoetm1Rraf/Apoetm1Rraf
Tg(Mx1-cre)29-4Her/0

(B6.Cg-Apoetm1Rraf Tg(Mx1-cre)29-4Her)
immune system phenotype J:196923
Apoetm1Unc/Apoetm1Unc
(B6.129P2-Apoetm1Unc/J)
abnormal B cell activation J:133606
abnormal CD4-positive, alpha-beta T cell number J:108154, J:47027
abnormal immune serum protein physiology J:61564
abnormal immune system morphology J:47027
abnormal immune system physiology J:61564
abnormal T cell number J:47027
blood vessel inflammation J:91058
decreased follicular B cell number J:133606
decreased interferon-gamma secretion J:47027
decreased marginal zone B cell number J:133606
decreased susceptibility to type IV hypersensitivity reaction J:61564
increased anti-double stranded DNA antibody level J:133606
increased anti-nuclear antigen antibody level J:133606
increased autoantibody level J:133606
increased B cell number J:133606
increased IgM level J:61564
increased immunoglobulin level J:133606
increased marginal zone B cell number J:133606
increased spleen weight J:61564
increased susceptibility to systemic lupus erythematosus J:133606
increased T-helper 2 cell number J:47027
Apoetm1Unc/Apoetm1Unc
(involves: 129P2/OlaHsd * C57BL/6)
lung inflammation J:83615
Apoetm1Unc/Apoetm1Unc
(B6.129P2-Apoetm1Unc)
abnormal cell-mediated immunity J:125366
abnormal dendritic cell physiology J:125366
increased CD4-positive, alpha-beta T cell number J:125366
increased susceptibility to parasitic infection J:125366
Apoetm1Unc/Apoetm1Unc
(B6.Cg-Apoetm1Unc Faslpr)
increased anti-double stranded DNA antibody level J:133606
increased anti-nuclear antigen antibody level J:133606
increased immunoglobulin level J:133606
increased susceptibility to systemic lupus erythematosus J:133606
Apoetm1Unc/Apoetm1Unc
Cbstm1Unc/Cbstm1Unc
Tg(Mt1-CBS)25Waku/0

(involves: 129P2/OlaHsd * C3H * C57BL/6)
increased circulating tumor necrosis factor level J:168131
increased Ly6C high monocyte number J:168131
increased monocyte cell number J:168131
Apoetm1Unc/Apoetm1Unc
Ccr1tm1Gao/Ccr1tm1Gao

(involves: 129P2/OlaHsd * 129S4/SvJae)
increased interferon-gamma secretion J:128063
Apoetm1Unc/Apoetm1Unc
Ccr2tm1Ifc/Ccr2tm1Ifc

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
impaired macrophage chemotaxis J:111471
Apoetm1Unc/Apoetm1Unc
Ccr2tm1Ifc/Ccr2tm1Ifc

(B6.Cg-Apoetm1Unc Ccr2tm1Ifc)
decreased monocyte cell number J:153310
Apoetm1Unc/Apoetm1Unc
Ccr2tm1Ifc/Ccr2tm1Ifc
Cx3cl1tm1Lira/Cx3cl1tm1Lira

(B6.Cg-Apoetm1Unc Cx3cl1tm1Lira Ccr2tm1Ifc)
decreased monocyte cell number J:153310
Apoetm1Unc/Apoetm1Unc
Ccr5tm1Blck/Ccr5tm1Blck

(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:128063
abnormal lymphocyte physiology J:128063
abnormal mononuclear phagocyte morphology J:128063
decreased interferon-gamma secretion J:128063
decreased T cell number J:128063
increased interleukin-10 secretion J:128063
Apoetm1Unc/Apoetm1Unc
Ccr5tm1Kuz/Ccr5tm1Kuz

(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:128063
abnormal lymphocyte physiology J:128063
abnormal mononuclear phagocyte morphology J:128063
decreased interferon-gamma secretion J:128063
decreased T cell number J:128063
increased interleukin-10 secretion J:128063
Apoetm1Unc/Apoetm1Unc
Cd36tm1Mfe/Cd36tm1Mfe

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
abnormal macrophage derived foam cell morphology J:61672
abnormal macrophage physiology J:61672
Apoetm1Unc/Apoetm1Unc
Cx3cl1tm1Sgs/Cx3cl1tm1Sgs

(B6.129-Apoetm1Unc Cx3cl1tm1Sgs)
impaired macrophage chemotaxis J:95279
increased macrophage derived foam cell number J:95279
Apoetm1Unc/Apoetm1Unc
Cxcl10tm1Adl/Cxcl10tm1Adl

(B6.129-Cxcl10tm1Adl Apoetm1Unc)
decreased CD4-positive, alpha-beta T cell number J:166204
impaired macrophage chemotaxis J:166204
Apoetm1Unc/Apoetm1Unc
Cyp4f13Gt(OST14770)Lex/Cyp4f13Gt(OST14770)Lex

(involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6)
abnormal macrophage chemotaxis J:289999
Apoetm1Unc/Apoetm1Unc
Cyp19a1tm1Esi/Cyp19a1tm1Esi

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6)
increased circulating C-reactive protein level J:184647
increased circulating interleukin-6 level J:184647
increased circulating tumor necrosis factor level J:184647
Apoetm1Unc/Apoetm1Unc
Faslpr/Faslpr

(MRL.Cg-Apoetm1Unc Faslpr)
increased anti-double stranded DNA antibody level J:133606
increased anti-nuclear antigen antibody level J:133606
increased autoantibody level J:133606
increased immunoglobulin level J:133606
increased susceptibility to systemic lupus erythematosus J:133606
Apoetm1Unc/Apoetm1Unc
Faslpr/Faslpr

(B6.Cg-Apoetm1Unc Faslpr)
decreased autoantibody level J:121671
decreased CD4-positive, alpha-beta T cell number J:121671
decreased CD8-positive, alpha-beta T cell number J:121671
enlarged lymph nodes J:121671
enlarged spleen J:121671
enlarged thymus J:121671
glomerulonephritis J:121671
increased anti-double stranded DNA antibody level J:121671
increased autoantibody level J:121671
increased IgG level J:121671
Apoetm1Unc/Apoetm1Unc
Faslgld/Faslgld

(B6.Cg-Faslgld Apoetm1Unc)
abnormal lymph node morphology J:91058
blood vessel inflammation J:91058
enlarged lymph nodes J:200141, J:91058
enlarged spleen J:91058
impaired macrophage phagocytosis J:91058
increased anti-nuclear antigen antibody level J:200141, J:91058
increased autoantibody level J:91058
increased IgG level J:91058
increased spleen weight J:200141, J:91058
increased T cell number J:91058
kidney inflammation J:200141
Apoetm1Unc/Apoetm1Unc
Gja5tm1Mchn/Gja5tm1Mchn
Tg(TIE2-lacZ)182Sato/0

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal neutrophil physiology J:162224
alveolitis J:162224
Apoetm1Unc/Apoetm1Unc
Glg1Gt(RST092)Byg/Glg1+

(B6J.129P2-Apoetm1Unc Glg1Gt(RST092)Byg)
decreased macrophage cell number J:226586
impaired macrophage chemotaxis J:226586
Apoetm1Unc/Apoetm1Unc
Hptm1Alev/Hptm1Alev

(involves: 129)
abnormal macrophage chemotaxis J:134942
Apoetm1Unc/Apoetm1Unc
Hsd11b1tm1Lex/Hsd11b1tm1Lex

(B6.129-Hsd11b1tm1Lex Apoetm1Unc)
abnormal cytokine secretion J:199430
abnormal macrophage derived foam cell morphology J:199430
decreased macrophage cell number J:199430
decreased tumor necrosis factor secretion J:199430
immune system phenotype J:199430
Apoetm1Unc/Apoetm1Unc
Il1r1tm1Imx/Il1r1tm1Imx

(B6.129-Il1r1tm1Imx Apoetm1Unc)
decreased circulating interleukin-6 level J:148173
Apoetm1Unc/Apoetm1Unc
Il1rntm1Dih/Il1rntm1Dih

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
abnormal macrophage chemotaxis J:132570
Apoetm1Unc/Apoetm1Unc
Il10tm1Cgn/Il10tm1Cgn

(involves: 129P2/OlaHsd * C57BL/6)
abnormal circulating cytokine level J:105858
increased circulating interferon-gamma level J:105858
increased circulating interleukin-12 level J:105858
Apoetm1Unc/Apoetm1Unc
Itgb3tm1Hyn/Itgb3tm1Hyn

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
lung inflammation J:83615
Apoetm1Unc/Apoetm1Unc
Klf15tm2Jain/Klf15tm2Jain
Tg(Tagln-cre)1Jjl/0

(involves: 129P2/OlaHsd * FVB/N)
blood vessel inflammation J:203920
increased macrophage cell number J:203920
Apoetm1Unc/Apoetm1Unc
Mmp9tm1Tvu/Mmp9tm1Tvu

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
decreased macrophage cell number J:110044
Apoetm1Unc/Apoetm1Unc
Ncf1tm1Shl/Ncf1tm1Shl

(involves: 129P2/OlaHsd * 129S2/SvPas)
decreased acute inflammation J:123854
Apoetm1Unc/Apoetm1Unc
Nck1tm1Paw/Nck1tm1Paw
Nck2tm3Paw/Nck2tm3Paw
Tg(Cdh5-cre/ERT2)1Rha/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased inflammatory response J:326659
Apoetm1Unc/Apoetm1Unc
Nfe2l2tm1Mym/Nfe2l2tm1Mym

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal macrophage physiology J:143903
Apoetm1Unc/Apoetm1Unc
Pla2g15tm1Ytan/Pla2g15tm1Ytan

(involves: 129S/SvEv * B6.129P2-Apoetm1Unc/J)
abnormal macrophage morphology J:97471
Apoetm1Unc/Apoetm1Unc
Soat1tm1Far/Soat1tm1Far

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J)
skin inflammation J:61147
Apoetm1Unc/Apoetm1Unc
Spp1tm1Blh/Spp1tm1Blh

(involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6J)
abnormal macrophage physiology J:86531
Apoetm1Unc/Apoetm1Unc
Tg(CAG-IL1RN)1Cga/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/1 * FVB)
decreased circulating serum amyloid protein level J:132570
Apoetm1Unc/Apoetm1Unc
Tg(CAG-IL1RN)2Cga/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/1 * FVB)
decreased circulating serum amyloid protein level J:132570
Apoetm1Unc/Apoetm1Unc
Tg(MSR1-Plau)1Ddi/0

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
heart inflammation J:101486
Apoetm2(APOE*3)Mae/Apoetm2(APOE*3)Mae
(involves: 129P2/OlaHsd * C57BL/6J)
decreased interleukin-6 secretion J:86768
decreased tumor necrosis factor secretion J:86768
Apoetm2(APOE*3)Mae/Apoetm2(APOE*3)Mae
Tg(Thy1-APPSwDutIowa)BWevn/?

(involves: 129P2/OlaHsd * C57BL/6)
abnormal microglial cell morphology J:136318
Apoetm3(APOE*4)Mae/Apoetm3(APOE*4)Mae
(involves: 129P2/OlaHsd * C57BL/6)
abnormal response to infection J:138241
increased interleukin-6 secretion J:86768
increased tumor necrosis factor secretion J:86768
Apoetm3(APOE*4)Mae/Apoetm3(APOE*4)Mae
Tg(Thy1-APPSwDutIowa)BWevn/?

(involves: 129P2/OlaHsd * C57BL/6)
abnormal microglial cell morphology J:136318
Apoftm1.1(KOMP)Vlcg/Apoftm1.1(KOMP)Vlcg
(C57BL/6N-Apoftm1.1(KOMP)Vlcg/Ucd)
increased basophil cell number J:211773
Apol6em1Hsul/Apol6em1Hsul
(Not Specified)
decreased inflammatory response J:344362
Apptm1Ck/Apptm1Ck
Tg(PDGFB-PSEN1M146L)2Jhd/0

(involves: 129 * Black Swiss * C57BL/6 * DBA/2 * SW)
abnormal microglial cell morphology J:102542
Apptm2.1Ldad/Apptm2.1Ldad
(involves: 129 * C57BL/6J)
myositis J:166989
Apptm2.1Tcs/Apptm2.1Tcs
(involves: C57BL/6)
microgliosis J:212758
Apptm2.1Tcs/Apptm2.1Tcs
Casttm1Tcs/Casttm1Tcs

(involves: 129P2/OlaHsd * C57BL/6)
microgliosis J:212758
Apptm3.1Tcs/Apptm3.1Tcs
(involves: C57BL/6)
microgliosis J:212758
Apptm3.1Tcs/Apptm3.1Tcs
Mapttm1.1(MAPT)Tcs/Mapttm1.1(MAPT)Tcs

(involves: 129S/SvEv * C57BL/6)
CNS inflammation J:278451
Appl1Gt(XM073)Byg/Appl1Gt(XM073)Byg
(B6.129P2-Appl1Gt(XM073)Byg)
immune system phenotype J:164696
increased T cell proliferation J:164696
Appl1tm1.2Test/Appl1tm1.2Test
(involves: 129X1/SvJ)
increased T cell proliferation J:164696
Aprttm1Dwm/Aprttm1Dwm
(129P2/OlaHsd-Aprttm1Dwm)
pyelonephritis J:38450
Aprttm1Jat/Aprttm1Jat
(involves: 129S2/SvPas * Black Swiss)
kidney inflammation J:33255
Aprttm1Jat/Aprttm1Jat
(involves: 129S2/SvPas * C57BL/6J)
kidney inflammation J:33255
Aprttm1Vri/Aprttm1Vri
(involves: 129P2/OlaHsd * C57BL/6)
kidney inflammation J:50874
Aptxtm1Pmc/Aptxtm1Pmc
Atmtm2.1Mfgc/Atmtm2.1Mfgc

(involves: 129 * C57BL/6)
abnormal CD4-positive helper T cell morphology J:316365
abnormal T cell differentiation J:316365
decreased T cell number J:316365
increased CD8-positive, alpha-beta T cell number J:316365
Aqp1tm1b(EUCOMM)Wtsi/Aqp1tm1b(EUCOMM)Wtsi
(C57BL/6N-Aqp1tm1b(EUCOMM)Wtsi/H)
increased neutrophil cell number J:211773
Aqp3m1Btlr/Aqp3m1Btlr
(C57BL/6J-Aqp3m1Btlr)
abnormal gut-associated lymphoid tissue morphology J:153279
increased susceptibility to induced colitis J:153279
Aqp4tm1.1Lmno/Aqp4tm1.1Lmno
(B6.Cg-Aqp4tm1.1Lmno)
increased susceptibility to parasitic infection J:193622
increased susceptibility to parasitic infection induced morbidity/mortality J:193622
Aqp4tm1.1Mysi/Aqp4tm1.1Mysi
(involves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj)
abnormal microglial cell physiology J:214906
Aqp9tm1Nlsn/Aqp9tm1Nlsn
(involves: 129S1/Sv)
decreased susceptibility to parasitic infection J:123305
Aqp11tm1.1(KOMP)Vlcg/Aqp11+
(B6N(Cg)-Aqp11tm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Aqp12tm1Rai/Aqp12tm1Rai
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
increased susceptibility to induced pancreatitis J:155920
ArTfm/Y
(involves: STOCK EdaTa Atp7aMo-blo)
abnormal myeloid leukocyte morphology J:110923
increased immature B cell number J:110923
Artm1Chc/Y
Tmem163Tg(ACTB-cre)2Mrt/0

(involves: 129S/SvEv * C57BL/6J * FVB/N)
increased osteoclast cell number J:81789
Artm1Chc/Artm1.1Chc
Tmem163Tg(ACTB-cre)2Mrt/0

(involves: 129S/SvEv * C57BL/6J * FVB/N)
enlarged thymus J:87193
Artm1Verh/Y
Rnase10tm1(cre)Hht/Rnase10+

(involves: 129S7/SvEvBrd * C57BL/6)
testis inflammation J:173897
Araftm1Mmc/Y
(involves: 129P2/OlaHsd * C57BL/6)
small thymus J:33951
Araftm1Mmc/Araftm1Mmc
(involves: 129P2/OlaHsd * C57BL/6)
small thymus J:33951
Arb2aem2(IMPC)Ccpcz/Arb2aem2(IMPC)Ccpcz
(C57BL/6NCrl-Arb2aem2(IMPC)Ccpcz/Ph)
abnormal thymus morphology J:211773
decreased Ly6C-positive NK T cell number J:211773
enlarged thymus J:211773
Arb2aTg(Tyr)TpNpin/Arb2aTg(Tyr)TpNpin
(involves: FVB/N)
thymus hypoplasia J:260599
Aregtm1Dle/Aregtm1Dle
Egftm1Dle/Egftm1Dle
Tgfatm1Unc/Tgfatm1Unc

(involves: 129P2/OlaHsd * C57BL/6)
dermatitis J:54980
Aregtm2c(EUCOMM)Hmgu/Aregtm2c(EUCOMM)Hmgu
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N)
immune system phenotype J:224904
increased susceptibility to Orthomyxoviridae infection J:224904
Aregtm2c(EUCOMM)Hmgu/Aregtm2c(EUCOMM)Hmgu
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * C57BL/6N * DBA/2)
immune system phenotype J:224904
increased susceptibility to Orthomyxoviridae infection J:224904
Arel1em1Bbc/Arel1+
(C57BL/6J-Arel1em1Bbc)
decreased acute inflammation J:280563
decreased response to antigen J:280563
Arel1em1Bbc/Arel1em1Bbc
(C57BL/6J-Arel1em1Bbc)
decreased acute inflammation J:280563
decreased response to antigen J:280563
Arf4tm1b(KOMP)Wtsi/Arf4+
(C57BL/6N-Arf4tm1b(KOMP)Wtsi/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Arfip1em1(IMPC)Mbp/Arfip1em1(IMPC)Mbp
(C57BL/6N-Arfip1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Arg1tm1.1Lky/Arg1+
Tg(Sftpc-Chia)#Lky/0

(involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2)
decreased macrophage cell number J:122735
Arg1tm1.1Pmu/Arg1tm1.1Pmu
(involves: C57BL/6 * NZB)
increased macrophage nitric oxide production J:143229
Arg1tm1Ekoe/Arg1tm1Ekoe
(involves: 129P2/OlaHsd)
abnormal macrophage physiology J:183882
Arg1tm1Pmu/Arg1tm1Pmu
Lyz2tm1(cre)Ifo/?

(B6.Cg-Arg1tm1Pmu Lyz2tm1(cre)Ifo)
decreased susceptibility to parasitic infection J:143229
Arg1tm1Pmu/Arg1tm1Pmu
Tg(Tek-cre)1Ywa/?

(B6.Cg-Tg(Tek-cre)1Ywa Arg1tm1Pmu)
abnormal macrophage physiology J:143229
decreased susceptibility to bacterial infection J:143229
increased macrophage nitric oxide production J:143229
Arg2em1(IMPC)Ccpcz/Arg2em1(IMPC)Ccpcz
(C57BL/6NCrl-Arg2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small spleen J:211773
Arhgap1tm1Yizh/Arhgap1tm1Yizh
(involves: 129S6/SvEvTac)
spleen hypoplasia J:101418
thymus hypoplasia J:101418
Arhgap1tm1Yizh/Arhgap1tm1Yizh
(involves: 129S6/SvEvTac * C57BL/6)
decreased spleen white pulp amount J:119516
spleen hypoplasia J:119516
Arhgap5tm1Jset/Arhgap5tm1Jset
(involves: 129S2/SvPas * C57BL/6J)
small thymus J:76484
Arhgap10em1(IMPC)Tcp/Arhgap10em1(IMPC)Tcp
(C57BL/6N-Arhgap10em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Arhgap15tm1Ehi/Arhgap15tm1Ehi
(B6.129-Arhgap15tm1Ehi)
abnormal leukocyte cell number J:174896
abnormal leukocyte morphology J:174896
abnormal macrophage morphology J:174896
abnormal neutrophil physiology J:174896
decreased lymphocyte cell number J:174896
decreased macrophage cell number J:174896
decreased monocyte cell number J:174896
decreased neutrophil cell number J:174896
decreased susceptibility to bacterial infection J:174896
immune system phenotype J:174896
Arhgap17Gt(RRN062)Byg/Arhgap17Gt(RRN062)Byg
(B6.129P2-Arhgap17Gt(RRN062)Byg)
increased susceptibility to induced colitis J:277297
increased tumor necrosis factor secretion J:277297
Arhgap17tm1b(EUCOMM)Wtsi/Arhgap17tm1b(EUCOMM)Wtsi
(C57BL/6N-Arhgap17tm1b(EUCOMM)Wtsi/Wtsi)
decreased B-1a cell number J:211773
decreased follicular B cell number J:211773
decreased mature B cell number J:211773
increased transitional stage T1 B cell number J:211773
Arhgap21Gt(RRR629)Byg/Arhgap21+
(B6.129P2-Arhgap21Gt(RRR629)Byg)
increased leukocyte cell number J:262703
increased neutrophil cell number J:262703
Arhgap25tm1a(KOMP)Wtsi/Arhgap25tm1a(KOMP)Wtsi
(involves: C57BL/6N)
abnormal cellular extravasation J:240521
abnormal neutrophil physiology J:240521
enhanced leukocyte migration J:240521
enhanced leukocyte tethering or rolling J:240521
increased acute inflammation J:240521
increased neutrophil cell number J:240521
Arhgap26tm1b(EUCOMM)Hmgu/Arhgap26tm1b(EUCOMM)Hmgu
(C57BL/6N-Arhgap26tm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Arhgap28em1(IMPC)Mbp/Arhgap28em1(IMPC)Mbp
(C57BL/6NCrl-Arhgap28em1(IMPC)Mbp/Mmucd)
small spleen J:211773
Arhgap30tm1a(EUCOMM)Wtsi/Arhgap30tm1a(EUCOMM)Wtsi
(C57BL/6N-Arhgap30tm1a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Arhgap45em1Ciphe/Arhgap45em1Ciphe
(C57BL/6-Arhgap45em1Ciphe)
decreased B cell number J:309971
decreased CD4-positive, alpha-beta T cell number J:309971
decreased CD8-positive, alpha-beta T cell number J:309971
decreased CD8-positive, naive alpha-beta T cell number J:309971
decreased DN1 thymic pro-T cell number J:309971
decreased lymphocyte chemotaxis J:309971
decreased naive B cell number J:309971
decreased T cell number J:309971
immune system phenotype J:309971
lymph node hypoplasia J:309971
Arhgdiatm1Ytk/Arhgdiatm1Ytk
(involves: 129S/SvEv * C57BL/6 * DBA)
decreased T cell number J:140671
tubulointerstitial nephritis J:57995
Arhgdiatm1Ytk/Arhgdiatm1Ytk
Arhgdibtm1Miyo/Arhgdibtm1Miyo

(involves: 129S/SvEv)
abnormal B cell physiology J:140671
abnormal leukocyte cell number J:140671
abnormal lymph node B cell domain morphology J:140671
abnormal mesenteric lymph node morphology J:140671
abnormal T cell physiology J:140671
abnormal thymus medulla morphology J:140671
decreased double-positive T cell number J:140671
decreased follicular B cell number J:140671
decreased immature B cell number J:140671
decreased marginal zone B cell number J:140671
decreased mature B cell number J:140671
decreased pre-B cell number J:140671
decreased T cell number J:140671
decreased T cell proliferation J:140671
decreased transitional stage B cell number J:140671
disorganized spleen B cell follicle J:140671
increased B cell proliferation J:140671
increased circulating interleukin-5 level J:140671
increased eosinophil cell number J:140671
increased single-positive T cell number J:140671
spleen hypoplasia J:140671
Arhgdibtm1Len/Arhgdibtm1Len
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:42604
increased B cell proliferation J:42604
Arhgdibtm1Miyo/Arhgdibtm1Miyo
(involves: 129S/SvEv)
decreased B cell number J:140671
decreased T cell number J:140671
Arhgef1tm1.1Rmt/Arhgef1tm1.1Rmt
(C57BL/6-Arhgef1tm1.1Rmt)
abnormal marginal zone B cell physiology J:113295
decreased B cell number J:113295
decreased B-1 B cell number J:113295
decreased follicular B cell number J:113295
decreased IgM level J:113295
decreased marginal zone B cell number J:113295
Arhgef1tm1a(EUCOMM)Wtsi/Arhgef1tm1a(EUCOMM)Wtsi
(C57BL/6N-Arhgef1tm1a(EUCOMM)Wtsi/Wtsi)
decreased CD8-positive, alpha-beta T cell number J:211773
decreased dendritic cell number J:211773
decreased immature NK cell number J:211773
decreased Ly6C-positive immature NK cell number J:211773
decreased marginal zone B cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
decreased memory-marker gamma-delta T cell number J:211773
increased CD4-positive, alpha-beta memory T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased CD8-positive, alpha-beta memory T cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased gamma-delta T cell number J:211773
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased KLRG1-positive NK cell number J:211773
increased Ly6C low monocyte number J:211773
increased Ly6C-positive NK T cell number J:211773
increased mature NK cell number J:211773
increased monocyte cell number J:211773
increased plasmacytoid dendritic cell number J:211773
Arhgef1tm1Djle/Arhgef1tm1Djle
(involves: 129S4/SvJae * C57BL/6)
abnormal neutrophil physiology J:129331
enlarged spleen J:129331
increased leukocyte cell number J:129331
Arhgef1tm1Djle/Arhgef1tm1Djle
(involves: 129S4/SvJae)
increased germinal center B cell number J:174313
Arhgef1tm1Kdf/Arhgef1tm1Kdf
(involves: 129S1/Sv * 129X1/SvJ)
abnormal humoral immune response J:99463
abnormal lymphocyte cell number J:99463
abnormal lymphocyte physiology J:99463
decreased B cell number J:99463
decreased B cell proliferation J:99463
decreased IgG level J:99463
decreased IgM level J:99463
decreased marginal zone B cell number J:99463
increased T cell proliferation J:99463
Arhgef2em1(IMPC)Mbp/Arhgef2em1(IMPC)Mbp
(C57BL/6N-Arhgef2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Arhgef2Gt(IST13976A8)Tigm/Arhgef2Gt(IST13976A8)Tigm
(involves: C57BL/6N)
abnormal macrophage physiology J:209086
decreased interferon-beta secretion J:209086
immune system phenotype J:209086
increased susceptibility to Orthomyxoviridae infection J:209086
Arhgef4tm1a(KOMP)Wtsi/Arhgef4tm1a(KOMP)Wtsi
(C57BL/6N-Arhgef4tm1a(KOMP)Wtsi/Wtsi)
decreased IgE level J:165965
decreased IgG1 level J:165965
decreased T cell number J:165965
increased mature B cell number J:165965
Arhgef5tm1.1Dwu/Arhgef5tm1.1Dwu
(involves: 129S1/Sv * 129S6/SvEvTac)
abnormal CD4-positive, alpha-beta T cell physiology J:157812
abnormal dendritic cell physiology J:157812
decreased eosinophil cell number J:157812
decreased interleukin-4 secretion J:157812
immune system phenotype J:157812
Arhgef6tm1Kdf/Arhgef6tm1Kdf
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell number J:137269
abnormal B cell physiology J:137269
abnormal humoral immune response J:137269
abnormal T cell physiology J:137269
decreased B cell proliferation J:137269
decreased CD4-positive, alpha-beta T cell number J:137269
decreased CD8-positive, alpha-beta T cell number J:137269
decreased interleukin-2 secretion J:137269
decreased lymphocyte cell number J:137269
decreased mature B cell number J:137269
decreased T cell proliferation J:137269
Arhgef6tm2e.1(EUCOMM)Wtsi/Y
(C57BL/6N-Arhgef6tm2e.1(EUCOMM)Wtsi/Tcp)
enlarged lymph nodes J:211773
Arhgef6tm2e.1(EUCOMM)Wtsi/Arhgef6tm2e.1(EUCOMM)Wtsi
(C57BL/6N-Arhgef6tm2e.1(EUCOMM)Wtsi/Tcp)
decreased lymphocyte cell number J:211773
Arhgef12tm1.1Wet/Arhgef12tm1.1Wet
Tg(Lck-cre)548Jxm/0

(involves: 129 * C57BL/6 * CBA)
abnormal T cell proliferation J:149560
Arhgef18tm1b(KOMP)Mbp/Arhgef18+
(C57BL/6N-Arhgef18tm1b(KOMP)Mbp/H)
increased basophil cell number J:211773
Arid1atm1.1Mag/Arid1atm1.1Mag
Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+

(involves: 129S6/SvEvTac * CD-1)
increased interleukin-6 secretion J:219794
Arid1bem1(IMPC)Tcp/Arid1b+
(C57BL/6NCrl-Arid1bem1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Arid2tm1a(EUCOMM)Wtsi/Arid2tm1a(EUCOMM)Wtsi
(involves: C57BL/6J * C57BL/6N)
immune system phenotype J:223458
Arid3atm1Pwt/Arid3atm1Pwt
(involves: 129S6/SvEvTac * C57BL/6)
abnormal B cell differentiation J:169178
abnormal class switch recombination J:169178
decreased B cell number J:169178
decreased B-1 B cell number J:169178
decreased B-1a cell number J:169178
decreased B-2 B cell number J:169178
decreased IgG1 level J:169178
decreased IgM level J:169178
decreased marginal zone B cell number J:169178
decreased pre-B cell number J:169178
decreased pro-B cell number J:169178
decreased transitional stage B cell number J:169178
decreased transitional stage T1 B cell number J:169178
decreased transitional stage T2 B cell number J:169178
Arid3btm1c(KOMP)Wtsi/Arid3btm1c(KOMP)Wtsi
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6J * C57BL/6N * SJL)
abnormal B cell differentiation J:236980
decreased B cell number J:236980
decreased B-1b cell number J:236980
decreased CD4-positive, alpha-beta T cell number J:236980
decreased immature B cell number J:236980
decreased pre-B cell number J:236980
decreased pre-pro B cell number J:236980
decreased pro-B cell number J:236980
decreased transitional stage B cell number J:236980
increased B-1a cell number J:236980
increased follicular B cell number J:236980
Arid4atm1Alb/Arid4atm1Alb
(involves: 129S7/SvEvBrd)
abnormal mononuclear cell differentiation J:141004
decreased B cell number J:141004
decreased leukocyte cell number J:141004
decreased lymphocyte cell number J:141004
decreased monocyte cell number J:141004
decreased neutrophil cell number J:141004
decreased T cell number J:141004
enlarged spleen J:141004
increased leukocyte cell number J:141004
increased T cell number J:141004
Arid4atm1Alb/Arid4atm1Alb
Arid4btm1Alb/Arid4b+

(involves: 129S7/SvEvBrd)
abnormal leukopoiesis J:141004
decreased B cell number J:141004
decreased lymphocyte cell number J:141004
decreased T cell number J:141004
enlarged spleen J:141004
hemophagocytosis J:141004
increased leukocyte cell number J:141004
increased monocyte cell number J:141004
increased neutrophil cell number J:141004
increased T cell number J:141004
Arid5atm1Rnis/Arid5atm1Rnis
(B6.Cg-Arid5atm1Rnis)
decreased circulating interleukin-6 level J:197418
decreased circulating tumor necrosis factor level J:197418
decreased susceptibility to experimental autoimmune encephalomyelitis J:197418
decreased T-helper 17 cell number J:197418
increased T cell number J:197418
Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
(involves: 129S4/SvJaeSor)
kidney inflammation J:117491
Arid5btm1Pjh/Arid5btm1Pjh
(involves: 129S4/SvJae * BALB/c)
abnormal immune system organ morphology J:70658
abnormal lymphopoiesis J:70658
decreased double-positive T cell number J:70658
decreased pro-B cell number J:70658
increased single-positive T cell number J:70658
spleen hypoplasia J:70658
thymus cortex hypoplasia J:70658
thymus hypoplasia J:70658
Arigg1NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg2NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg3NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg4NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg5NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg6NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg7NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg8BALB/cByJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg9NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigg10BALB/cByJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased anti-erythrocyte antigen antibody level J:93737
Arigm1BALB/cByJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased IgM level J:93737
Arigm2NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased IgM level J:93737
Arigm3NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased IgM level J:93737
Arigm4NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased IgM level J:93737
Arigm5NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased IgM level J:93737
Arigm6NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased IgM level J:93737
Arigm7NZB/BlNJ/?
(involves: BALB/cByJ * NZB/BlNJ)
increased IgM level J:93737
Arih1em3Gpt/Arih1em3Gpt
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6JGpt)
decreased interferon-beta secretion J:330879
decreased interleukin-6 secretion J:330879
increased susceptibility to Herpesvirales infection J:330879
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:330879
Arih1em3Gpt/Arih1em3Gpt
Lyz2em1(icre)Gpt/Lyz2+

(C57BL/6JGpt-Arih1em3Gpt Lyz2em1(icre)Gpt)
decreased circulating interferon-beta level J:330879
decreased circulating interleukin-6 level J:330879
decreased interferon-beta secretion J:330879
decreased interleukin-6 secretion J:330879
immune system phenotype J:330879
increased susceptibility to Herpesvirales infection J:330879
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:330879
Arih1em3Gpt/Arih1em3Gpt
Lyz2em1(icre)Gpt/Lyz2+
Trex1em1Gpt/Trex1em1Gpt

(C57BL/6JGpt-Arih1em3Gpt Trex1em1Gpt Lyz2em1(icre)Gpt)
immune system phenotype J:330879
Arih2tm1Mak/Arih2tm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
dermatitis J:191066
heart inflammation J:191066
increased inflammatory response J:191066
liver inflammation J:191066
lung inflammation J:191066
Arih2tm1Mak/Arih2tm1Mak
(B6.129P2-Arih2tm1Mak)
abnormal dendritic cell physiology J:191066
increased inflammatory response J:191066
Arl3Gt(OST263303)Lex/Arl3Gt(OST263303)Lex
(involves: 129S5/SvEvBrd)
bile duct inflammation J:107331
Arl6ip5tm1.2Jwzh/Arl6ip5tm1.2Jwzh
(B6.129X1-Arl6ip5tm1.2Jwzh)
abnormal immune system organ morphology J:187133
Arl16em1(IMPC)Ccpcz/Arl16em1(IMPC)Ccpcz
(C57BL/6NCrl-Arl16em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small spleen J:211773
Armc2tm1b(EUCOMM)Hmgu/Armc2+
(C57BL/6N-Armc2tm1b(EUCOMM)Hmgu/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Armcx1em1(IMPC)Mbp/Y
(C57BL/6N-Armcx1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Armh4em1(IMPC)H/Armh4em1(IMPC)H
(C57BL/6N-Armh4em1(IMPC)H/H)
enlarged spleen J:211773
Arnttm1.1Gonz/Arnttm1.2Gonz
Tg(Lck-cre)I57Jxm/0

(involves: 129X1/SvJ * ICR)
abnormal immune system physiology J:85934
ArpBALB/c/ArpBALB/c
(involves: B10.D2 * BALB/c)
abnormal lymph node morphology J:7273
abnormal Peyer's patch morphology J:6549
lymph node hypoplasia J:6549
spleen hyperplasia J:6549
thymus hyperplasia J:6549
ArpBALB/c/ArpBALB/c
LusC57BL/10/LusC57BL/10

(involves: B10.D2 * BALB/c)
abnormal lymph node morphology J:7273
Arpc1btm1a(EUCOMM)Wtsi/Arpc1btm1a(EUCOMM)Wtsi
(C57BL/6N-Arpc1btm1a(EUCOMM)Wtsi/Wtsi)
decreased CD4-positive, alpha-beta T cell number J:211773
decreased KLRG1-positive NK cell number J:211773
decreased Ly6C-positive mature NK cell number J:211773
decreased macrophage cell number J:211773
decreased marginal zone precursor B cell number J:211773
decreased mature NK cell number J:211773
decreased NK cell number J:211773
decreased transitional stage T2 B cell number J:211773
increased CD4-positive, alpha-beta memory T cell number J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased CD103-positive CD11b-low dendritic cell number J:211773
increased effector memory T-helper cell number J:211773
increased immature NK cell number J:211773
increased KLRG1+ CD4 alpha-beta T cell number J:211773
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased KLRG1-positive T-helper cell number J:211773
increased leukocyte cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased memory-marker CD4-negative NK T cell number J:211773
increased memory-marker NK cell number J:211773
increased plasma cell number J:211773
Arpc4tm1a(EUCOMM)Wtsi/Arpc4+
(B6JTyr;B6N-Arpc4tm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:165965
Arpc4tm1c(EUCOMM)Wtsi/Arpc4tm1c(EUCOMM)Wtsi
Krt14tm1(cre)Wbm/Krt14+

(B6.Cg-Arpc4tm1c(EUCOMM)Wtsi Krt14tm1(cre)Wbm)
dermatitis J:253986
Arrb2tm1Rjl/Arrb2tm1Rjl
(involves: 129X1/SvJ * C57BL/6)
abnormal circulating tumor necrosis factor level J:112607
abnormal lymphocyte physiology J:76872
increased acute inflammation J:112607
increased circulating interleukin-6 level J:112607
increased interleukin-6 secretion J:112607
increased interleukin-12b secretion J:112607
increased susceptibility to endotoxin shock J:112607
increased tumor necrosis factor secretion J:112607
Arrdc4em1(IMPC)Tcp/Arrdc4em1(IMPC)Tcp
(C57BL/6N-Arrdc4em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
Arsatm1Gie/Arsatm1Gie
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal microglial cell morphology J:37978
Arsgtm1Tdi/Arsgtm1Tdi
(involves: 129S2/SvPas * C57BL/6)
abnormal macrophage morphology J:185592
abnormal microglial cell morphology J:185592
abnormal perivascular macrophage morphology J:185592
microgliosis J:185592, J:254592
Art1tm1b(EUCOMM)Wtsi/Art1tm1b(EUCOMM)Wtsi
(C57BL/6N-Art1tm1b(EUCOMM)Wtsi/Tcp)
enlarged lymph nodes J:211773
increased basophil cell number J:211773
Art2atm1Fkn/Art2atm1Fkn
Art2btm1Fkn/Art2btm1Fkn

(NOD.129S4(B6)-Art2atm1Fkn Art2btm1Fkn/Lt)
decreased T cell apoptosis J:108097
Art2atm1Fkn/Art2atm1Fkn
Art2btm1Fkn/Art2btm1Fkn
Cd38tm1Lnd/Cd38tm1Lnd

(NOD.129(B6)-Cd38tm1Lnd Art2atm1Fkn Art2btm1Fkn/Lt)
decreased susceptibility to autoimmune diabetes J:108097
Arti1C57BL/6J/Arti1C57BL/6J
Arti2C57BL/6J/Arti2C57BL/6J

(involves: C57BL/6J * DBA/2J)
abnormal thymus involution J:85261
Arti1DBA/2J/Arti1DBA/2J
Arti2DBA/2J/Arti2DBA/2J

(involves: C57BL/6J * DBA/2J)
abnormal thymus involution J:85261
Arvm2MRL/MpJ/Arvm2MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
abnormal immune system physiology J:63511
asa/asa
(either: A/J or BALB/c or DBA/2J)
increased autoantibody level J:2843
myocarditis J:2843
Asah1tm1.2Geno/Asah1tm1.2Geno
(involves: C57BL/6)
abnormal circulating cytokine level J:285931
abnormal lymph node morphology J:285931
abnormal thymus morphology J:285931
decreased B cell number J:285931
decreased CD4-positive, alpha-beta T cell number J:285931
decreased CD8-positive, alpha-beta T cell number J:285931
decreased double-positive T cell number J:285931
decreased leukocyte cell number J:285931
decreased lymphocyte cell number J:285931
decreased splenocyte number J:285931
decreased T cell number J:285931
enlarged spleen J:285931
increased circulating CXCL10 level J:285931
increased granulocyte number J:285931
increased macrophage cell number J:285931
increased macrophage derived foam cell number J:285931
increased monocyte cell number J:285931
lung inflammation J:285931
Asah1tm1Medin/Asah1tm1Medin
(involves: 129S6/SvEvTac * CD-1)
abnormal chemokine secretion J:232306
abnormal circulating chemokine level J:232306
enlarged lymph nodes J:232306
enlarged spleen J:232306
enlarged thymus J:232306
increased circulating interleukin-12b level J:232306
increased eosinophil cell number J:232306
increased leukocyte cell number J:232306
increased macrophage derived foam cell number J:232306
increased monocyte cell number J:232306
increased neutrophil cell number J:232306
increased spleen weight J:232306
pale spleen J:232306
Asb1em1(IMPC)Ccpcz/Asb1em1(IMPC)Ccpcz
(C57BL/6N-Asb1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Asb1tm1Wehi/Asb1tm1Wehi
(involves: C57BL/6)
small spleen J:71266
spleen hypoplasia J:71266
Asb2tm1.1Lutz/Asb2tm1.1Lutz
Tg(Mx1-cre)1Cgn/0

(involves: 129S2/SvPas * C57BL/6 * CBA)
abnormal dendritic cell physiology J:200966
Asb2tm2b(KOMP)Wtsi/Asb2+
(C57BL/6N-Asb2tm2b(KOMP)Wtsi/Kmpc)
decreased effector memory T-helper cell number J:211773
decreased Ly6C-positive immature NK cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased dendritic cell number J:211773
increased eosinophil cell number J:211773
increased Ly6C-positive immature NK cell number J:211773
increased Ly6C-positive mature NK cell number J:211773
increased Ly6C-positive NK T cell number J:211773
increased NK cell number J:211773
increased T cell number J:211773
Asb4em1(IMPC)Ccpcz/Asb4em1(IMPC)Ccpcz
(C57BL/6N-Asb4em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
Asb5em1(IMPC)Ccpcz/Asb5em1(IMPC)Ccpcz
(C57BL/6N-Asb5em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Asb7em1(IMPC)Ccpcz/Asb7em1(IMPC)Ccpcz
(C57BL/6N-Asb7em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
Asb16em1(IMPC)Ccpcz/Asb16em1(IMPC)Ccpcz
(C57BL/6N-Asb16em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Asbb1BALB/c/Asbb1BALB/c
(involves: BALB/c * C57BL/6J)
increased susceptibility to systemic lupus erythematosus J:76486
Asbb2BALB/c/Asbb2C57BL/6J
(involves: BALB/c * C57BL/6J)
increased susceptibility to systemic lupus erythematosus J:76486
Asbb2C57BL/6J/Asbb2C57BL/6J
(involves: BALB/c * C57BL/6J)
increased susceptibility to systemic lupus erythematosus J:76486
Asbb3C57BL/6J/Asbb3C57BL/6J
(involves: BALB/c * C57BL/6J)
increased susceptibility to systemic lupus erythematosus J:76486
Ascc2tm1a(EUCOMM)Wtsi/Ascc2+
(C57BL/6N-Ascc2tm1a(EUCOMM)Wtsi/Bay)
enlarged spleen J:211773
Ascl4em1(IMPC)J/Ascl4em1(IMPC)J
(C57BL/6NJ-Ascl4em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ascl5em1(IMPC)Ccpcz/Ascl5em1(IMPC)Ccpcz
(C57BL/6NCrl-Ascl5em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Asf1bm1Btlr/Asf1bm1Btlr
(C57BL/6J-Asf1bm1Btlr)
increased IgE level J:267479
Asgr1tm1Sau/Asgr1tm1Sau
(B6.129S4-Asgr1tm1Sau)
increased susceptibility to bacterial infection J:136946
Asgr2tm1Her/Asgr2tm1Her
(B6.129S7-Asgr2tm1Her)
increased susceptibility to bacterial infection J:136946
Ash1lGt(AL0395)Wtsi/Ash1lGt(AL0395)Wtsi
(involves: 129P2/OlaHsd * C57BL/6J)
blepharitis J:227516
Ash1ltm2b(EUCOMM)Hmgu/Ash1l+
(C57BL/6N-Ash1ltm2b(EUCOMM)Hmgu/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu/Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu
(B6.FVB-Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu)
glomerulonephritis J:208213
immune system phenotype J:208213
increased autoantibody level J:208213
increased circulating interleukin-6 level J:208213
increased circulating tumor necrosis factor level J:208213
increased IgA level J:208213
increased IgG1 level J:208213
increased IgG2a level J:208213
increased IgG2b level J:208213
increased IgM level J:208213
increased interleukin-6 secretion J:208213
increased susceptibility to autoimmune disorder J:208213
increased susceptibility to bacterial infection J:208213
increased susceptibility to bacterial infection induced morbidity/mortality J:208213
increased susceptibility to endotoxin shock J:208213
increased susceptibility to induced arthritis J:208213
increased tumor necrosis factor secretion J:208213
Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu/Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu
Il6tm1Kopf/Il6tm1Kopf

(B6.Cg-Ash1lTn(pb-Act-RFP)1.AF0-180T25Zhu Il6tm1Kopf)
abnormal inflammatory response J:208213
increased susceptibility to induced arthritis J:208213
Asic2em1(IMPC)Mbp/Asic2em1(IMPC)Mbp
(C57BL/6N-Asic2em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Asic3em1(IMPC)Mbp/Asic3em1(IMPC)Mbp
(C57BL/6NCrl-Asic3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Asltm1Brle/Asltm1Brle
(involves: 129S7/SvEvBrd)
decreased lymphocyte cell number J:180208
decreased spleen germinal center number J:180208
increased macrophage cell number J:180208
increased spleen red pulp amount J:180208
thymus cortex hypoplasia J:180208
Asm1MRL/MpJ/?
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
abnormal immune system physiology J:66459
Asm2MRL/MpJ/?
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
salivary gland inflammation J:66459
Asphd1em1(IMPC)Ccpcz/Asphd1em1(IMPC)Ccpcz
(C57BL/6NCrl-Asphd1em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Aspscr1em1(IMPC)Tcp/Aspscr1em1(IMPC)Tcp
(C57BL/6NCrl-Aspscr1em1(IMPC)Tcp/Tcp)
decreased neutrophil cell number J:211773
enlarged lymph nodes J:211773
increased lymphocyte cell number J:211773
Asq1IQI/Asq1IQI
(involves: IQI * C57BL/6CrSlc)
salivary gland inflammation J:127310
Ass1tm1.1Ekoe/Ass1tm1.1Ekoe
Tg(Vil1-cre)997Gum/0

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
immune system phenotype J:203474
Aste1tm1a(KOMP)Wtsi/Aste1tm1a(KOMP)Wtsi
(B6JTyr;B6N-Aste1tm1a(KOMP)Wtsi/Wtsi)
decreased leukocyte cell number J:175295
Asxl1tm1.1Iaai/Asxl1tm1.1Iaai
Tet2tm1.1Iaai/Tet2tm1.1Iaai
Tg(Mx1-cre)1Cgn/0

(involves: 129S/SvEv * C57BL/6 * CBA)
abnormal myelopoiesis J:208092
Asxl1tm1.1Iaai/Asxl1tm1.1Iaai
Tg(Mx1-cre)1Cgn/0

(involves: 129S/SvEv * C57BL/6 * CBA)
abnormal myelopoiesis J:208092
decreased leukocyte cell number J:208092
decreased mature B cell number J:208092
decreased monocyte cell number J:208092
decreased neutrophil cell number J:208092
Asxl1tm1.1Iaai/Asxl1tm1.1Iaai
Tg(VAV1-cre)1Graf/0

(involves: 129S/SvEv * C57BL/6)
abnormal myelopoiesis J:208092
decreased leukocyte cell number J:208092
decreased mature B cell number J:208092
decreased monocyte cell number J:208092
decreased neutrophil cell number J:208092
decreased splenocyte number J:208092
Asxl1tm1.1Mjxu/Asxl1+
(involves: 129 * C57BL/6)
abnormal leukocyte morphology J:208085
abnormal myelopoiesis J:208085
abnormal neutrophil morphology J:208085
abnormal neutrophil physiology J:208085
abnormal spleen morphology J:208085
decreased B cell number J:208085
decreased leukocyte cell number J:208085
decreased neutrophil cell number J:208085
enlarged spleen J:208085
increased leukocyte cell number J:208085
increased monocyte cell number J:208085
Asxl1tm1.1Mjxu/Asxl1tm1.1Mjxu
(involves: 129 * C57BL/6)
abnormal leukocyte morphology J:208085
abnormal neutrophil morphology J:208085
abnormal spleen white pulp morphology J:208085
decreased B cell number J:208085
decreased leukocyte cell number J:208085
decreased lymphocyte cell number J:208085
decreased spleen red pulp amount J:208085
decreased spleen weight J:208085
increased monocyte cell number J:208085
increased single-positive T cell number J:208085
myeloid hyperplasia J:208085
small spleen J:208085
spleen atrophy J:208085
Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
(B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH)
decreased leukocyte cell number J:175295
Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
(C57BL/6N-Asxl1tm1a(EUCOMM)Wtsi/Cnrm)
decreased B cell number J:165965
Asxl1tm1Bc/Asxl1tm1Bc
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal immune system cell morphology J:155898
abnormal immune system organ morphology J:155898
abnormal lymphopoiesis J:155898
abnormal thymus morphology J:155898
decreased B cell number J:155898
decreased CD4-positive, alpha-beta T cell number J:155898
decreased pre-B cell number J:155898
decreased T cell number J:155898
increased double-negative T cell number J:155898
spleen hyperplasia J:155898
Atad2btm1b(EUCOMM)Hmgu/Atad2btm1b(EUCOMM)Hmgu
(C57BL/6N-Atad2btm1b(EUCOMM)Hmgu/Ics)
decreased NK T cell number J:211773
Atcayji/Atcayji
(Not Specified)
abnormal thymus cortex morphology J:14903
abnormal thymus medulla morphology J:14903
abnormal thymus morphology J:14903
Atf1tm1.1Arte/Atf1tm1.1Arte
(involves: C57BL/6)
immune system phenotype J:191723
Atf2Tg(Gzma-Klra1)7Wum/Atf2+
(involves: C57BL/6)
abnormal NK cell physiology J:61178
decreased circulating interferon-gamma level J:61178
decreased NK cell number J:61178
decreased NK T cell number J:61178
immune system phenotype J:61178
Atf2tm1b(EUCOMM)Hmgu/Atf2+
(C57BL/6N-Atf2tm1b(EUCOMM)Hmgu/Ccpcz)
abnormal spleen morphology J:211773
Atf2tm1Glm/Atf2tm1Glm
(involves: 129S2/SvPas)
eye inflammation J:30611
increased susceptibility to bacterial infection J:30611
Atf2tm1Glm/Atf2tm1Glm
(C.Cg-Atf2tm1Glm)
abnormal cytokine secretion J:67176
immune system phenotype J:67176
increased susceptibility to endotoxin shock J:67176
increased susceptibility to Herpesvirales infection J:67176
increased susceptibility to Picornaviridae infection J:67176
Atf3tm1Dron/Atf3tm1Dron
(involves: 129X1/SvJ * C57BL/6)
abnormal T-helper 2 physiology J:140112
decreased IgG2a level J:140112
increased interleukin-4 secretion J:140112
increased interleukin-5 secretion J:140112
increased interleukin-13 secretion J:140112
lung inflammation J:140112
Atf4tm1(KOMP)Mbp/Atf4+
(C57BL/6NCrl-Atf4tm1(KOMP)Mbp/MbpMmucd)
decreased monocyte cell number J:211773
Atg3tm1.1Ywh/Atg3tm1.1Ywh
Fnip1m1Btlr/Fnip1m1Btlr
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+

(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J)
absent B cells J:234285
Atg3tm1.1Ywh/Atg3tm1.1Ywh
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJaeSor * C57BL/6)
abnormal T cell morphology J:172749
increased T cell apoptosis J:172749
Atg3tm1.1Ywh/Atg3tm1.1Ywh
Tg(Lck-cre)548Jxm/0

(involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * CBA)
abnormal T cell morphology J:172749
decreased CD4-positive, alpha-beta T cell number J:172749
decreased CD8-positive, alpha-beta T cell number J:172749
decreased T cell proliferation J:172749
increased T cell apoptosis J:172749
spleen hypoplasia J:172749
thymus hypoplasia J:172749
Atg5tm1Myok/Atg5tm1Myok
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S/SvEv)
abnormal circulating chemokine level J:235399
abnormal macrophage physiology J:235399
decreased circulating interleukin-10 level J:235399
glomerulonephritis J:235399
increased anti-double stranded DNA antibody level J:235399
increased anti-nuclear antigen antibody level J:235399
increased autoantibody level J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
increased circulating interleukin-12b level J:235399
increased IgG level J:235399
increased lymphocyte cell number J:235399
increased monocyte cell number J:235399
increased neutrophil cell number J:235399
increased susceptibility to systemic lupus erythematosus J:235399
Atg5tm1Nmz/Atg5tm1Nmz
(involves: 129 * BALB/c * C57BL/6)
abnormal thymus cortex morphology J:140583
Atg5tm1Nmz/Atg5tm1Nmz
Tg(CAG-EGFP/Map1lc3b)53Nmz/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal thymus morphology J:140583
abnormal thymus physiology J:140583
Atg5tm1Nmz/Atg5tm1Nmz
Tg(Cd4-cre)1Cwi/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal T cell morphology J:211733
abnormal T cell physiology J:211733
abnormal T cell subpopulation ratio J:211733
decreased CD4-positive, alpha-beta T cell number J:211733
decreased CD8-positive, alpha-beta T cell number J:211733
decreased T cell number J:211733
decreased T cell proliferation J:211733
Atg7tm1Tchi/Atg7tm1Tchi
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6NCrlj * C57BL/10 * CBA/Ca * CBA/JNCrlj)
abnormal leukocyte morphology J:176843
decreased B cell number J:176843
decreased leukocyte cell number J:176843
decreased NK cell number J:176843
decreased T cell number J:176843
Atg7tm1Tchi/Atg7tm1Tchi
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj)
abnormal circulating chemokine level J:235399
abnormal macrophage physiology J:235399
decreased circulating interleukin-10 level J:235399
glomerulonephritis J:235399
increased anti-double stranded DNA antibody level J:235399
increased anti-nuclear antigen antibody level J:235399
increased autoantibody level J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
increased circulating interleukin-12b level J:235399
increased IgG level J:235399
increased lymphocyte cell number J:235399
increased monocyte cell number J:235399
increased neutrophil cell number J:235399
increased susceptibility to systemic lupus erythematosus J:235399
Atg7tm1Tchi/Atg7tm1Tchi
Lyz2tm1(cre)Ifo/Lyz2+
Tg(CAG-EGFP/Map1lc3b)53Nmz/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * DBA/2)
abnormal circulating chemokine level J:235399
abnormal macrophage physiology J:235399
decreased circulating interleukin-10 level J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
Atg7tm1Tchi/Atg7tm1Tchi
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Defa6-icre)1Rsb/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
small intestinal inflammation J:206084
Atg7tm1Tchi/Atg7tm1Tchi
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL)
ileum inflammation J:206084
intestinal inflammation J:206084
Atg9atm1Aki/Atg9atm1Aki
(involves: 129/Sv * C57BL/6)
abnormal innate immunity J:155552
increased interferon-beta secretion J:155552
increased interleukin-6 secretion J:155552
Atg16l1tm1.1Mvlc/Atg16l1tm1.1Mvlc
(C57BL/6-Atg16l1tm1.1Mvlc)
abnormal macrophage physiology J:206931
immune system phenotype J:206931
increased circulating interleukin-1 beta level J:206931
increased macrophage cytokine production J:206931
increased susceptibility to bacterial infection J:206931
Atg16l1tm1a(EUCOMM)Wtsi/Atg16l1tm1a(EUCOMM)Wtsi
(C57BL/6N-Atg16l1tm1a(EUCOMM)Wtsi/Wtsi)
abnormal thymus topology J:239583
absent connection between subcutaneous lymph vessels and lymph sac J:239583
blood in lymph vessels J:239583
Atg16l1tm1Aki/Atg16l1tm1Aki
(involves: 129/Sv * C57BL/6)
abnormal macrophage physiology J:141420
increased interleukin-1 beta secretion J:141420
increased interleukin-18 secretion J:141420
increased susceptibility to induced colitis J:141420
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tcrdtm1Mom/Tcrdtm1Mom
Tg(Vil1-cre)997Gum/0

(involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N * SJL)
abnormal cytokine level J:340266
increased susceptibility to colitis induced morbidity/mortality J:340266
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tg(Defa6-icre)1Rsb/0

(involves: C57BL/6)
increased susceptibility to colitis induced morbidity/mortality J:340266
increased susceptibility to induced colitis J:340266
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tg(Itgax-cre)1-1Reiz/?

(involves: C57BL/6 * C57BL/6N * CBA)
immune system phenotype J:221019
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tg(Vil1-cre)997Gum/?

(involves: C57BL/6J * C57BL/6N * SJL)
abnormal chemokine level J:221019
abnormal circulating interleukin level J:221019
abnormal cytokine level J:221019
cecum inflammation J:221019
increased circulating interleukin-1 beta level J:221019
increased circulating interleukin-6 level J:221019
increased macrophage cell number J:221019
increased susceptibility to bacterial infection J:221019
Atg16l1tm1Kuv/Atg16l1tm1Kuv
Tg(Vil1-cre)997Gum/0

(B6.Cg-Atg16l1tm1Kuv Tg(Vil1-cre)997Gum)
increased susceptibility to induced colitis J:269933
small intestinal inflammation J:269933
Atg16l1tm1Kuv/Atg16l1tm1Kuv
Tg(Vil1-cre)997Gum/0
Xbp1tm2Glm/Xbp1tm2Glm

(B6.Cg-Atg16l1tm1Kuv Xbp1tm2Glm Tg(Vil1-cre)997Gum)
small intestinal inflammation J:269933
Atg16l1tm1Kuv/Atg16l1tm1Kuv
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
ileum inflammation J:206084
intestinal inflammation J:206084
Atg16l2m1Anu/Atg16l2m1Anu
(C57BL/6NCrlAnu-Atg16l2m1Anu)
decreased lymphocyte cell number J:104190
Atl1tm1.2Cbla/Atl1tm1.2Cbla
Reep1Gt(OST398247)Tigm/Reep1Gt(OST398247)Tigm

(B6.Cg-Reep1Gt(OST398247)Tigm Atl1tm1.2Cbla)
increased susceptibility to otitis media J:334532
Atl2tm2b(EUCOMM)Hmgu/Atl2+
(C57BL/6N-Atl2tm2b(EUCOMM)Hmgu/H)
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Atl3em1(IMPC)Tcp/Atl3em1(IMPC)Tcp
(C57BL/6N-Atl3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Atmm1Btlr/Atmm1Btlr
(C57BL/6J-Atmm1Btlr)
decreased CD4-positive, alpha-beta T cell number J:265252
decreased CD8-positive, alpha-beta T cell number J:265252
decreased response to antigen J:265252
decreased single-positive T cell number J:265252
decreased T cell number J:265252
impaired humoral immune response J:265252
increased IgM level J:265252
Atmm2Btlr/Atmm2Btlr
(C57BL/6J-Atmm2Btlr)
decreased CD4-positive, alpha-beta T cell number J:265253
decreased CD8-positive, naive alpha-beta T cell number J:265253
decreased single-positive T cell number J:265253
increased central memory CD8 positive, alpha-beta T cell number J:265253
increased effector memory CD4-positive, alpha-beta T cell number J:265253
Atmm3Btlr/Atmm3Btlr
(C57BL/6J-Atmm3Btlr)
increased B-1a cell number J:272820
increased macrophage cell number J:272820
AtmM4Btlr/AtmM4Btlr
(C57BL/6J-AtmM4Btlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:272821
Atmm5Btlr/Atmm5Btlr
(C57BL/6J-Atmm5Btlr)
abnormal lymphocyte morphology J:272824
decreased interleukin-1 beta secretion J:272824
impaired macrophage phagocytosis J:272824
increased B-1 B cell number J:272824
Atmm6Btlr/Atmm6Btlr
(C57BL/6J-Atmm6Btlr)
abnormal CD4-positive T cell differentiation J:274964
abnormal CD8-positive, alpha-beta T cell differentiation J:274964
abnormal T cell differentiation J:274964
decreased CD4-positive, alpha-beta T cell number J:274964
decreased CD8-positive, naive alpha-beta T cell number J:274964
decreased T cell number J:274964
increased CD8-positive, alpha-beta memory T cell number J:274964
increased central memory CD4-positive, alpha-beta T cell number J:274964
increased central memory CD8 positive, alpha-beta T cell number J:274964
increased effector memory CD4-positive, alpha-beta T cell number J:274964
Atmtm1.1Mmpl/Atmtm1.1Mmpl
(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J)
decreased T cell number J:226414
increased B cell number J:226414
Atmtm1Awb/Atm+
Rad50tm2Jpt/Rad50tm2Jpt

(involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6)
decreased macrophage cell number J:103922
Atmtm1Awb/Atmtm1Awb
(either: 129S6/SvEvTac-Atmtm1Awb or (involves: 129S6/SvEvTac * NIH Black Swiss))
decreased activated T cell number J:34193
decreased double-positive T cell number J:34193
decreased T cell number J:34193
immune system phenotype J:34193
increased double-positive T cell number J:34193
Atmtm1Awb/Atmtm1Awb
(involves: 129S6/SvEvTac)
abnormal class switch recombination J:150435
decreased CD4-positive, alpha-beta T cell number J:90941
decreased CD8-positive, alpha-beta T cell number J:90941
immune system phenotype J:126920
Atmtm1Awb/Atmtm1Awb
(129S6/SvEvTac-Atmtm1Awb/J)
decreased single-positive T cell number J:226414
decreased T cell number J:226414
increased B cell number J:226414
increased double-positive T cell number J:226414
Atmtm1Awb/Atmtm1Awb
Paxxem1Spj/Paxxem1Spj

(involves: A/J * C57BL/6NTac)
abnormal class switch recombination J:236776
decreased B cell number J:236776
decreased splenocyte number J:236776
decreased T cell number J:236776
Atmtm1Awb/Atmtm1Awb
Rad52tm1Aps/Rad52tm1Aps

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
decreased CD4-positive, alpha-beta T cell number J:90941
decreased CD8-positive, alpha-beta T cell number J:90941
Atmtm1Bal/Atmtm1Bal
(involves: 129S4/SvJae)
abnormal microglial cell physiology J:44190
abnormal T cell physiology J:35914
decreased IgG2a level J:35914
decreased IgG2b level J:35914
decreased IgG3 level J:35914
decreased IgG level J:35914
decreased pre-B cell number J:35914
decreased thymocyte number J:35914
small thymus J:35914
Atmtm1Fwa/Atmtm1Fwa
(involves: 129S4/SvJae * C57BL/6)
decreased immature B cell number J:61201
decreased lymphocyte cell number J:61201
decreased pre-B cell number J:61201
decreased splenocyte number J:61201
decreased T cell number J:61201
decreased thymocyte number J:61201
Atmtm1Fwa/Atmtm1Fwa
(involves: 129S4/SvJae)
abnormal class switch recombination J:191288
Atmtm1Led/Atmtm1Led
(involves: 129S6/SvEvTac * Black Swiss)
abnormal T cell differentiation J:36561
decreased CD4-positive, alpha-beta T cell number J:36561
increased double-positive T cell number J:36561
small thymus J:36561
thymus cortex hypoplasia J:36561
Atmtm1Mfl/Atmtm1Mfl
(involves: 129T2/SvEms * C57BL/6J)
abnormal immune system cell morphology J:69726
abnormal immune system organ morphology J:69726
abnormal T cell differentiation J:69726
decreased thymocyte number J:69726
enlarged spleen J:69726
increased double-negative T cell number J:69726
increased single-positive T cell number J:69726
small lymph nodes J:69726
small spleen J:69726
small thymus J:69726
Atmtm1Pmc/Atmtm1Pmc
Trp73tm2Mak/Trp73tm2Mak

(involves: 129P2/OlaHsd * C57BL/6J)
decreased thymocyte apoptosis J:157905
Atmtm1Shzh/Atmtm2.1Fwa
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+

(involves: 129 * 129S6/SvEvTac)
abnormal class switch recombination J:191288
Atmtm2.1Fwa/Atmtm2.1Fwa
Tg(VAV1-cre)1Graf/0

(involves: 129S6/SvEvTac)
decreased B cell number J:277750
decreased T cell number J:277750
decreased thymocyte number J:277750
Atmtm2.1Mfgc/Atmtm2.1Mfgc
(C57BL/6-Atmtm2.1Mfgc)
abnormal T cell differentiation J:316365
decreased T cell number J:316365
Atmintm1.1Jhh/Atmintm1.1Jhh
(C57BL/6-Atmintm1.1Jhh)
thymus hypoplasia J:167544
Atmintm1.1Jhh/Atmintm1.1Jhh
Cd79atm1(cre)Reth/Cd79a+

(B6.Cg-Cd79atm1(Cre)Reth Atmintm1.1Jhh)
decreased B cell number J:230105
decreased IgG1 level J:230105
decreased immature B cell number J:230105
increased B cell apoptosis J:230105
Atmintm1.1Jhh/Atmintm1.1Jhh
Cd79atm1(cre)Reth/Cd79a+
Tg(IghMyc)22Bri/0

(B6.Cg-Cd79atm1(Cre)Reth Atmintm1.1Jhh Tg(IghMyc)22Bri)
decreased B cell number J:230105
decreased immature B cell number J:230105
increased B cell apoptosis J:230105
Atmintm1.2Jhh/Atmintm1.2Jhh
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S1/Sv * BALB/c * C57BL/6)
enlarged spleen J:191832
immune system phenotype J:191832
increased B cell number J:191832
increased immature B cell number J:191832
increased pre-B cell number J:191832
increased spleen weight J:191832
Atmintm1.2Jhh/Atmintm1.2Jhh
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6)
abnormal B cell differentiation J:191832
abnormal B cell physiology J:191832
decreased immature B cell number J:191832
decreased mature B cell number J:191832
decreased pre-B cell number J:191832
decreased spleen weight J:191832
small spleen J:191832
Atmintm1.2Jhh/Atmintm1.2Jhh
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
decreased B cell number J:191832
decreased lymphocyte cell number J:191832
decreased mature B cell number J:191832
decreased pre-B cell number J:191832
immune system phenotype J:191832
Atmintm1.2Jhh/Atmintm1.2Jhh
Trp53tm1Brn/Trp53tm1Brn
Cd79atm1(cre)Reth/Cd79a+

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
decreased B cell number J:191832
decreased immature B cell number J:191832
Atn1tm1b(EUCOMM)Wtsi/Atn1tm1b(EUCOMM)Wtsi
(C57BL/6N-Atn1tm1b(EUCOMM)Wtsi/Cnrm)
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
increased neutrophil cell number J:211773
Atp1a1em1(IMPC)Ccpcz/Atp1a1+
(C57BL/6NCrl-Atp1a1em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Atp1a3Myk/Atp1a3+
(involves: 129S1/SvImJ * C57BL/6J * C57BL/6NCr * FVB/NCr)
microgliosis J:151948
Atp2a2tm1Ges/Atp2a2+
(involves: 129X1/SvJ)
abnormal osteoclast differentiation J:198051
Atp2b4tm1Ges/Atp2b4tm1Ges
(involves: 129X1/SvJ * Black Swiss)
enlarged submandibular lymph nodes J:91844
Atp2c2em1(IMPC)Tcp/Atp2c2em1(IMPC)Tcp
(C57BL/6NCrl-Atp2c2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Atp4am1Btlr/Atp4am1Btlr
(involves: C57BL/6J)
abnormal spleen morphology J:179090
enlarged spleen J:179090
Atp5if1em1Jpy/Atp5if1em1Jpy
(C57BL/6J-Atp5if1em1Jpy)
decreased neutrophil cell number J:312819
decreased susceptibility to colitis induced morbidity/mortality J:312819
Atp5mc1em1(IMPC)H/Atp5mc1em1(IMPC)H
(C57BL/6NTac-Atp5mc1em1(IMPC)H/H)
increased neutrophil cell number J:211773
Atp5mgtm1b(EUCOMM)Hmgu/Atp5mg+
(C57BL/6N-Atp5mgtm1b(EUCOMM)Hmgu/H)
decreased eosinophil cell number J:211773
enlarged spleen J:211773
Atp5mktm1b(EUCOMM)Wtsi/Atp5mktm1b(EUCOMM)Wtsi
(C57BL/6N-Atp5mktm1b(EUCOMM)Wtsi/H)
increased leukocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Atp6v0a2tm1Kdb/Atp6v0a2tm1Kdb
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:274048
decreased alpha-beta T cell number J:274048
decreased CD4-positive, alpha-beta T cell number J:274048
decreased T cell number J:274048
Atp6v0d1tm1b(EUCOMM)Hmgu/Atp6v0d1+
(C57BL/6N-Atp6v0d1tm1b(EUCOMM)Hmgu/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Atp6v0d2tm1Ywc/Atp6v0d2tm1Ywc
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:117744
abnormal osteoclast morphology J:117744
Atp6v1b2tm1b(KOMP)Wtsi/Atp6v1b2+
(C57BL/6N-Atp6v1b2tm1b(KOMP)Wtsi/Tcp)
small lymph nodes J:211773
Atp6v1c1tm1b(NCOM)Mfgc/Atp6v1c1+
(C57BL/6N-Atp6v1c1tm1b(NCOM)Mfgc/Tcp)
increased leukocyte cell number J:211773
Atp6v1hem1Xhd/Atp6v1h+
(involves: C57BL/6)
abnormal osteoclast differentiation J:239439
abnormal osteoclast physiology J:239439
Atp7aMo-3Btlr/Y
(C57BL/6J-Atp7aMo-3Btlr)
decreased susceptibility to prion infection J:188598
Atp7aMo-blo/Y
(B6.Cg-Atp7aMo-blo/J)
osteoarthritis J:36378
Atp7aMo-ml/Y
(involves: C3Hf/He)
decreased spleen weight J:12745
Atp7btx-J/Atp7btx-J
(C3H/HeJ-Atp7btx-J/J)
increased eosinophil cell number J:24233
Atp8b1em1(IMPC)Tcp/Atp8b1em1(IMPC)Tcp
(C57BL/6NCrl-Atp8b1em1(IMPC)Tcp/Tcp)
increased leukocyte cell number J:211773
Atp10am1Anu/Atp10am1Anu
(C57BL/6NCrlAnu-Atp10am1Anu)
immune system phenotype J:104190
Atp11atm1a(KOMP)Wtsi/Atp11atm1a(KOMP)Wtsi
(C57BL/6N-Atp11atm1a(KOMP)Wtsi/Wtsi)
abnormal thymus morphology J:239583
Atp11cambr/Y
(C57BL/6-Atp11cambr)
abnormal B cell differentiation J:171924
abnormal humoral immune response J:171924
decreased B cell number J:171924
decreased B-1 B cell number J:171924
decreased B-1a cell number J:171924
decreased B-1b cell number J:171924
decreased B-2 B cell number J:171924
decreased follicular B cell number J:171924
decreased immature B cell number J:171924
decreased leukocyte cell number J:171924
decreased lymphocyte cell number J:171924
decreased mature B cell number J:171924
decreased pre-B cell number J:171924
decreased pro-B cell number J:171924
decreased T cell number J:171924
Atp11cambr/Y
Tg(H2-Ea-Il7)10Rhdr/0

(involves: C57BL/6 * C57BL/6JApb * DBA/2)
decreased B cell number J:171924
Atp11cambr/Y
Tg(IghelMD4)4Ccg/0

(involves: C57BL/6 * C57BL/6JApb)
decreased immature B cell number J:171924
decreased pro-B cell number J:171924
Atp11cambr/Y
Tg(Vav-BCL2)69Jad/0

(involves: C57BL/6 * C57BL/6J * C57BL/6JApb)
decreased B cell number J:171924
decreased immature B cell number J:171924
decreased pre-B cell number J:171924
Atp11cem1(IMPC)J/Y
(C57BL/6NJ-Atp11cem1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Atp11cem1(IMPC)J/Atp11cem1(IMPC)J
(C57BL/6NJ-Atp11cem1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Atp11cm1Btlr/Y
(involves: C57BL/6J)
absent follicular B cells J:171925
arrested B cell differentiation J:171925
decreased B cell number J:185495, J:171925
decreased B-1 B cell number J:171925
decreased B-2 B cell number J:171925
decreased IgA level J:171925
decreased IgG1 level J:171925
decreased IgM level J:171925
decreased immature B cell number J:171925
decreased transitional stage B cell number J:171925
decreased transitional stage T1 B cell number J:171925
decreased transitional stage T2 B cell number J:171925
decreased transitional stage T3 B cell number J:171925
immune system phenotype J:185495, J:171925
Atp11cm1Btlr/Y
Tg(BCL2)22Wehi/0

(involves: C57BL/6J * C57BL/6JWehi * SJL/Wehi)
decreased B cell number J:171925
decreased follicular B cell number J:171925
decreased mature B cell number J:171925
increased marginal zone B cell number J:171925
Atp11cm1Btlr/Y
Tg(IghmHyHEL10,IgkHyHEL10)4Ccg/0

(involves: C57BL/6 * C57BL/6J * C57BL/6JSfdAnu)
decreased B cell number J:171925
Atp11cm1Btlr/Atp11cm1Btlr
(involves: C57BL/6J)
decreased B cell number J:185495
immune system phenotype J:185495, J:171925
Atp11cm1Btlr/Atp11cm2Btlr
(involves: C57BL/6J)
decreased B cell number J:171925
Atp11cm2Anu/Y
(C57BL/6JAnu-Atp11cm2Anu/AnuApb)
decreased B cell number J:171924
Atp11cm2Btlr/Y
(involves: C57BL/6J)
decreased B cell number J:185495, J:171925
immune system phenotype J:185495
Atp11cm2Btlr/Atp11cm2Btlr
(involves: C57BL/6J)
decreased B cell number J:185495
immune system phenotype J:185495
Atp13a3em1(IMPC)J/Atp13a3em1(IMPC)J
(C57BL/6NJ-Atp13a3em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Atp13a5tm1Lex/Atp13a5tm1Lex
(B6;129S5-Atp13a5tm1Lex/Mmucd)
decreased NK cell number J:171883
Atrtm1Bal/Atrtm2Bal
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6)
abnormal thymus involution J:123200
decreased thymocyte number J:123200
kidney inflammation J:123200
Atrtm1Ofc/Atrtm1Ofc
(Not Specified)
decreased spleen weight J:151542
decreased thymus weight J:151542
Atxn3tm1a(KOMP)Wtsi/Atxn3tm1a(KOMP)Wtsi
(C57BL/6N-Atxn3tm1a(KOMP)Wtsi/Wtsi)
increased anti-nuclear antigen antibody level J:211773
AU040320em1Janc/AU040320em2Janc
(FVB/N-AU040320em1Janc AU040320em2Janc)
decreased susceptibility to Parvoviridae infection J:229089
Auhem1(IMPC)Tcp/Auhem1(IMPC)Tcp
(C57BL/6NCrl-Auhem1(IMPC)Tcp/Tcp)
increased eosinophil cell number J:211773
Aurkatm1b(EUCOMM)Hmgu/Aurka+
(B6N(Cg)-Aurkatm1b(EUCOMM)Hmgu/J)
decreased leukocyte cell number J:211773
Aviltm2(cre)Fawa/Aviltm2(cre)Fawa
(B6J.129P2-Aviltm2(cre)Fawa)
increased susceptibility to experimental autoimmune encephalomyelitis J:265529
Avptm1b(EUCOMM)Wtsi/Avp+
(C57BL/6N-Avptm1b(EUCOMM)Wtsi/H)
decreased large unstained cell number J:211773
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Avpr1atm1Sbhu/Avpr1atm1Sbhu
(involves: C57BL/6)
abnormal B cell differentiation J:105892
abnormal immunoglobulin level J:105892
decreased IgG2b level J:105892
increased B-1a cell number J:105892
increased IgG2a level J:105892
AW112010em2Flv/AW112010em2Flv
(involves: C57BL/6N)
decreased circulating interleukin-6 level J:267975
decreased circulating interleukin-12b level J:267975
decreased interleukin-6 secretion J:267975
decreased interleukin-12b secretion J:267975
decreased susceptibility to induced colitis J:267975
increased susceptibility to bacterial infection J:267975
increased susceptibility to bacterial infection induced morbidity/mortality J:267975
Awat2em1(IMPC)Mbp/Y
(C57BL/6NCrl-Awat2em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
Awat2tm1.2Golc/Y
(involves: 129 * C57BL/6 * C57BL/6J)
abnormal lymphangiogenesis J:308387
blepharitis J:308387
eye inflammation J:308387
Awat2tm1.2Golc/Awat2tm1.2Golc
(involves: 129 * C57BL/6 * C57BL/6J)
abnormal lymphangiogenesis J:308387
blepharitis J:308387
eye inflammation J:308387
awgTg(GBts1env)832Pkw/awgTg(GBts1env)832Pkw
(involves: C57BL/6J * SJL)
thymus atrophy J:43273
Axltm1Grl/Axltm1Grl
Mertktm1Grl/Mertktm1Grl

(involves: C57BL/6J)
increased anti-double stranded DNA antibody level J:70420
Axltm1Grl/Axltm1Grl
Mertktm1Grl/Mertktm1Grl
Tyro3tm1Grl/Tyro3tm1Grl

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal B cell activation J:70420
abnormal macrophage physiology J:70420
abnormal professional antigen presenting cell physiology J:70420
abnormal susceptibility to autoimmune disorder J:70420
abnormal T cell activation J:70420
enlarged lymph nodes J:70420
enlarged spleen J:54681, J:70420
increased anti-double stranded DNA antibody level J:70420
increased autoantibody level J:70420
increased B cell proliferation J:70420
increased circulating tumor necrosis factor level J:70420
increased lymphocyte cell number J:70420
increased splenocyte apoptosis J:54681
increased T cell proliferation J:70420
joint inflammation J:70420
Axltm1Grl/Axltm1Grl
Tyro3tm1Grl/Tyro3tm1Grl

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
increased anti-double stranded DNA antibody level J:70420
Azgp1tm1.1Sbah/Azgp1tm1.1Sbah
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:118213
Azi2tm1Aki/Azi2tm1Aki
(Not Specified)
abnormal dendritic cell differentiation J:204786
abnormal dendritic cell physiology J:204786
decreased interferon-alpha secretion J:204786
decreased interleukin-6 secretion J:204786
decreased tumor necrosis factor secretion J:204786
immune system phenotype J:204786
Azi2tm1Aki/Azi2tm1Aki
Tbkbp1tm1Aki/Tbkbp1tm1Aki

(Not Specified)
abnormal dendritic cell physiology J:204786
decreased interferon-alpha secretion J:204786
decreased interleukin-6 secretion J:204786
decreased tumor necrosis factor secretion J:204786
immune system phenotype J:204786
b2b227Clo/b2b227Clo
(C57BL/6J-b2b227Clo)
spleen hypoplasia J:175213
b2b386.1Clo/b2b386.1Clo
(C57BL/6J-b2b386.1Clo)
absent spleen J:175213
b2b386Clo/b2b386Clo
(C57BL/6J-b2b386Clo)
absent spleen J:175213
b2b954Clo/b2b954Clo
(C57BL/6J-b2b954Clo)
thymus hypoplasia J:175213
b2b1249Clo/b2b1249Clo
(C57BL/6J-b2b1249Clo)
thymus hypoplasia J:175213
b2b1702Clo/b2b1702Clo
(C57BL/6J-b2b1702Clo)
spleen hypoplasia J:175213
thymus hypoplasia J:175213
b2b1941Clo/b2b1941Clo
(C57BL/6J-b2b1941Clo)
athymia J:175213
b2b2025Clo/b2b2025Clo
(C57BL/6J-b2b2025Clo)
absent spleen J:175213
spleen hypoplasia J:175213
b2b2059Clo/b2b2059Clo
(C57BL/6J-b2b2059Clo)
spleen hypoplasia J:175213
b2b2140Clo/b2b2140Clo
(C57BL/6J-b2b2140Clo)
spleen hypoplasia J:175213
b2b2187Clo/b2b2187Clo
(C57BL/6J-b2b2187Clo)
thymus hypoplasia J:175213
b2b2463Clo/b2b2463Clo
(C57BL/6J-b2b2463Clo)
thymus hypoplasia J:175213
b2b2588Clo/b2b2588Clo
(C57BL/6J-b2b2588Clo)
thymus hypoplasia J:175213
b2b2696.1Clo/b2b2696.1Clo
(C57BL/6J-b2b2696.1Clo)
absent spleen J:175213
b2b2696.2Clo/b2b2696.2Clo
(C57BL/6J-b2b2696.2Clo)
thymus hypoplasia J:175213
b2b2696Clo/b2b2696Clo
(C57BL/6J-b2b2696Clo)
absent spleen J:175213
b2b2736.2Clo/b2b2736.2Clo
(C57BL/6J-b2b2736.2Clo)
thymus hypoplasia J:175213
b2b2736Clo/b2b2736Clo
(C57BL/6J-b2b2736Clo)
accessory spleen J:175213
spleen hypoplasia J:175213
thymus hypoplasia J:175213
b2b2821Clo/b2b2821Clo
(C57BL/6J-b2b2821Clo)
thymus hypoplasia J:175213
b2b2966Clo/b2b2966Clo
(C57BL/6J-b2b2966Clo)
thymus hypoplasia J:175213
b2b3077.2Clo/b2b3077.2Clo
(C57BL/6J-b2b3077.2Clo)
thymus hypoplasia J:175213
b2b3077Clo/b2b3077Clo
(C57BL/6J-b2b3077Clo)
thymus hypoplasia J:175213
b2b3121Clo/b2b3121Clo
(C57BL/6J-b2b3121Clo)
thymus hypoplasia J:175213
b2b3260.2Clo/b2b3260.2Clo
(C57BL/6J-b2b3260.2Clo)
abnormal thymus morphology J:175213
thymus hypoplasia J:175213
b2b3260Clo/b2b3260Clo
(C57BL/6J-b2b3260Clo)
abnormal thymus morphology J:175213
thymus hypoplasia J:175213
B2mtm1Jae/B2mtm1Jae
(involves: 129S2/SvPas * C57BL/6J)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:80910
abnormal cytotoxic T cell physiology J:80910
decreased CD8-positive, alpha-beta T cell number J:80910, J:744
increased gamma-delta intraepithelial T cell number J:744
increased gamma-delta T cell number J:744
B2mtm1Jae/B2mtm1Jae
(involves: 129S2/SvPas)
decreased CD8-positive, alpha-beta T cell number J:166104
B2mtm1Jae/B2mtm1Jae
(B6.129S2-B2mtm1Jae)
decreased interleukin-4 secretion J:64283
decreased susceptibility to parasitic infection J:64283
increased interleukin-3 secretion J:64283
increased tumor necrosis factor secretion J:64283
B2mtm1Jae/B2mtm1Jae
Cd4tm1Jrp/Cd4tm1Jrp

(involves: 129S2/SvPas * C57BL/6)
increased CD8-positive, alpha-beta T cell number J:45168
B2mtm1Jae/B2mtm1Jae
Foxp3sfOtcspf/Y

(involves: 129/Rl * 129S2/SvPas)
abnormal immune system organ morphology J:20865
abnormal interleukin level J:20865
abnormal lymph node morphology J:20865
abnormal tumor necrosis factor level J:20865
dermatitis J:20865
enlarged lymph nodes J:20865
enlarged spleen J:20865
increased CD4-positive, alpha-beta T cell number J:20865
increased IgG level J:20865
increased IgM level J:20865
increased immunoglobulin level J:20865
increased plasma cell number J:20865
B2mtm1Jae/B2mtm1Jae
Rr94tm3.2Litt/Rr94tm3.2Litt

(involves: 129P2/OlaHsd * 129S2/SvPas * FVB/N)
abnormal T cell differentiation J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
increased T cell proliferation J:158962
B2mtm1Jae/B2mtm1Jae
Rr96tm1.1Yzo/Rr96tm1.1Yzo

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal T cell differentiation J:130559
B2mtm1Jae/B2mtm1Jae
Tg(H2-K-Cd86)27All/0

(involves: 129S2/SvPas * C57BL/6 * CBA)
absent B cells J:112475
B2mtm1Jae/B2mtm1Jae
Tg(LckNotch1)9Erob/?

(involves: 129S2/SvPas * C57BL/6 * CBA)
increased CD8-positive, alpha-beta T cell number J:93005
lymph node hypoplasia J:93005
B2mtm1Jae/B2mtm1Jae
Themistm1Lov/Themistm1Lov

(involves: 129)
abnormal CD8-positive, alpha-beta T cell differentiation J:151075
B2mtm1Jae/B2mtm1Jae
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6J)
small intestinal inflammation J:108572
B2mtm1Jae/B2mtm1Jae
Toxtm1.1Kay/Toxtm1.1Kay

(involves: 129S6/SvEvTac * 129S2/SvPas)
abnormal CD8-positive, alpha-beta T cell number J:131287
B2mtm1Jae/B2mtm1Jae
Zbtb7btm1Litt/Zbtb7btm1.2Litt

(involves: 129S2/SvPas * C57BL/6)
abnormal CD8-positive, alpha-beta T cell differentiation J:141144
abnormal double-positive T cell morphology J:141144
B2mtm1Unc/B2m+
(involves: 129P2/OlaHsd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:64451
decreased level of surface class I molecules J:64451
B2mtm1Unc/B2mtm1Unc
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell number J:113083
absent CD8-positive, alpha-beta T cells J:64451
decreased level of surface class I molecules J:64451
B2mtm1Unc/B2mtm1Unc
(NOD.129P2-B2mtm1Unc)
absent CD8-positive, alpha-beta T cells J:121685
decreased susceptibility to autoimmune diabetes J:121685, J:17000
B2mtm1Unc/B2mtm1Unc
(involves: 129P2/OlaHsd * NOD/Lt)
insulitis J:93557
B2mtm1Unc/B2mtm1Unc
(B6.129P2-B2mtm1Unc/DcrJ)
abnormal interleukin level J:123934
abnormal tumor necrosis factor level J:123934
decreased CD8-positive, alpha-beta T cell number J:123934
decreased IgG level J:110885
decreased susceptibility to autoimmune diabetes J:135214
decreased susceptibility to bacterial infection J:123934
increased IgM level J:110885
increased susceptibility to infection induced morbidity/mortality J:123934
increased T-helper 1 cell number J:123934
B2mtm1Unc/B2mtm1Unc
Cd4tm1Mak/Cd4tm1Mak
Cd8atm2.1(Cd4)Asin/Cd8atm2.1(Cd4)Asin

(involves: 129 * C57BL/6)
abnormal T cell physiology J:180236
B2mtm1Unc/B2mtm1Unc
Ciitatm1Ccum/Ciitatm1Ccum

(NOD.Cg-B2mtm1Unc Ciitatm1Ccum)
decreased single-positive T cell number J:107051
decreased susceptibility to autoimmune diabetes J:107051
B2mtm1Unc/B2mtm1Unc
Emv30b/Emv30b
Prkdcscid/Prkdcscid
Tg(B2M)55Hpl/?
Mcph1Tg(HLA-A2.1)1Enge/?

(NOD.Cg-B2mtm1Unc Mcph1Tg(HLA-A2.1)1Enge Emv30b Prkdcscid Tg(B2M)55Hpl/Dvs)
decreased susceptibility to autoimmune diabetes J:109851
B2mtm1Unc/B2mtm1Unc
H2-Ab1b-tm1Doi/H2-Ab1b-tm1Doi
Lattm1.1Mal/Lattm1.1Mal

(involves: 129P2/OlaHsd * 129S2/SvPas)
absent CD4-positive, alpha-beta T cells J:77098
absent CD8-positive, alpha-beta T cells J:77098
immune system phenotype J:77098
B2mtm1Unc/B2mtm1Unc
H2-D1b-tm1Bpe/H2-D1b-tm1Bpe

(involves: 129P2/OlaHsd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:41077
B2mtm1Unc/B2mtm1Unc
Il2tm1Hor/Il2tm1Hor

(involves: 129 * C57BL/6)
abnormal CD4-positive T cell differentiation J:39981
abnormal CD4-positive, alpha-beta T cell physiology J:51450
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:39981
abnormal CD8-positive, alpha beta T cell morphology J:51450
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:39981
colitis J:39981, J:51450
B2mtm1Unc/B2mtm1Unc
Il2rgtm1.1Asin/Il2rgtm1Wjl
Tg(Cd8a*-cre)B8Asin/0

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:190889
B2mtm1Unc/B2mtm1Unc
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:190889
B2mtm1Unc/B2mtm1Unc
Lattm1.1Mal/Lattm1.1Mal

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal immune system morphology J:77098
B2mtm1Unc/B2mtm1Unc
Prkdcscid/Prkdcscid

(NOD.Cg-B2mtm1Unc Prkdcscid)
abnormal NK cell physiology J:102141
abnormal response to transplant J:102141
absent lymphocyte J:102141
arrested B cell differentiation J:102141
arrested T cell differentiation J:102141
decreased level of surface class I molecules J:102141
increased macrophage cell number J:102141
B2mtm1Unc/B2mtm1Unc
Rr381em2Kap/Rr381em2Kap

(involves: 129P2/OlaHsd * C57BL/6)
absent CD8-positive, alpha-beta T cells J:333471
B2mtm1Unc/B2mtm1Unc
Tespa1tm1Smoc/Tespa1tm1Smoc

(involves: 129 * 129P2/OlaHsd * C57BL/6)
abnormal CD8-positive, alpha beta T cell morphology J:186446
B2mtm1Unc/B2mtm1Unc
Tg(B2M)55Hpl/0

(NOD.Cg-B2mtm1Unc Tg(B2M)55Hpl/Dvs)
decreased susceptibility to autoimmune diabetes J:71837
immune system phenotype J:71837
B2mtm1Unc/B2mtm1Unc
Tg(B2M)55Hpl/Tg(B2M)55Hpl
Mcph1Tg(HLA-A2.1)1Enge/Mcph1Tg(HLA-A2.1)1Enge

(NOD.Cg-B2mtm1Unc Mcph1Tg(HLA-A2.1)1Enge Tg(B2M)55Hpl)
increased susceptibility to autoimmune diabetes J:109851
B2mtm1Unc/B2mtm1Unc
Tg(GFAP-B2m)9Mdos/?

(involves: 129P2/OlaHsd * C57BL/6 * NOD/ShiLtJ)
absent CD8-positive, alpha-beta T cells J:135214
decreased susceptibility to autoimmune diabetes J:135214
B2mtm1Unc/B2mtm1Unc
Tg(GFAP-B2m)#Mdos/?

(involves: 129P2/OlaHsd * C57BL/6 * NOD/ShiLtJ)
absent CD8-positive, alpha-beta T cells J:135214
decreased susceptibility to autoimmune diabetes J:135214
B2mtm1Unc/B2mtm1Unc
Tg(HLA-A/H2-D/B2M)1Dvs/0

(NOD.Cg-B2mtm1Unc Tg(HLA-A/H2-D/B2M)1Dvs)
abnormal CD8-positive, alpha-beta T cell physiology J:121685
abnormal cell-mediated immunity J:121685
abnormal cytotoxic T cell physiology J:121685
decreased CD8-positive, alpha-beta T cell number J:121685
increased susceptibility to autoimmune diabetes J:121685
B2mtm1Unc/B2mtm1Unc
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0

(NOD.Cg-B2mtm1Unc Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs)
abnormal CD8-positive, alpha beta T cell morphology J:93553
decreased susceptibility to autoimmune diabetes J:93553
B2mtm1Unc/B2mtm1Unc
X/Yaa

(BXSB.129P2(B6)-B2mtm1Unc/Dcr)
increased anti-nuclear antigen antibody level J:179430
increased susceptibility to systemic lupus erythematosus J:179430
B2mtm1Unc/B2mtm1Unc
Zbtb7btm4.1Itan/Zbtb7btm4.1Itan

(involves: 129P2/OlaHsd)
increased CD8-positive, alpha-beta T cell number J:193321
B3galt2tm1.1(KOMP)Vlcg/B3galt2+
(C57BL/6N-B3galt2tm1.1(KOMP)Vlcg/Tcp)
decreased lymphocyte cell number J:211773
B3gnt2Gt(OST237555)Lex/B3gnt2Gt(OST237555)Lex
(involves: 129S5/SvEvBrd * C57BL/6N)
abnormal macrophage physiology J:125556
increased interleukin-1 beta secretion J:125556
increased interleukin-6 secretion J:125556
increased T cell proliferation J:125556
increased tumor necrosis factor secretion J:125556
B3gnt5tm1Big/B3gnt5tm1Big
(C57BL/6-B3gnt5tm1Big)
abnormal spleen germinal center morphology J:166763
abnormal spleen morphology J:166763
absent spleen marginal zone J:166763
decreased B cell number J:166763
enlarged lymph nodes J:166763
enlarged spleen J:166763
increased spleen white pulp amount J:166763
intermingled spleen red and white pulp J:166763
B3gnt5tm1Nari/B3gnt5tm1Nari
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell morphology J:161366
increased IgG2a level J:161366
increased IgG2b level J:161366
increased IgG level J:161366
B3gnt5tm2.1Big/B3gnt5tm2.1Big
(involves: 129/Sv * C57BL/6 * FVB/N)
abnormal spleen germinal center morphology J:166763
abnormal spleen morphology J:166763
absent spleen marginal zone J:166763
decreased B cell number J:166763
enlarged lymph nodes J:166763
enlarged spleen J:166763
increased spleen white pulp amount J:166763
intermingled spleen red and white pulp J:166763
B3gnt6tm1Lx/B3gnt6tm1Lx
(involves: 129S1/Sv * C57BL/6J)
increased interferon-gamma secretion J:123826
increased interleukin-2 secretion J:123826
increased macrophage cell number J:123826
increased monocyte cell number J:123826
increased susceptibility to induced colitis J:123826
increased T cell number J:123826
increased tumor necrosis factor secretion J:123826
B3gnt6tm1Lx/B3gnt6tm1Lx
C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc
Tg(Vil1-cre)997Gum/0

(involves: 129S1/Sv * C57BL/6J * SJL)
small intestinal inflammation J:239765
B3gnt7tm1e.1(KOMP)Wtsi/B3gnt7tm1e.1(KOMP)Wtsi
(C57BL/6N-B3gnt7tm1e.1(KOMP)Wtsi/Ucd)
enlarged spleen J:211773
B4galnt1tm1Rlp/B4galnt1tm1Rlp
Hexbtm1Rlp/Hexbtm1Rlp

(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
abnormal macrophage morphology J:53080
B4galnt2tm1Jbl/B4galnt2tm1Jbl
(involves: 129S1/Sv)
abnormal B cell number J:217719
increased neutrophil cell number J:217719
B4galnt3tm1a(EUCOMM)Wtsi/B4galnt3tm1a(EUCOMM)Wtsi
(C57BL/6N-B4galnt3tm1a(EUCOMM)Wtsi/Ics)
increased CD8-positive, alpha-beta T cell number J:165965
B4galt1tm1Yiw/B4galt1tm1Yiw
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal leukocyte physiology J:106669
abnormal neutrophil physiology J:106669
decreased acute inflammation J:106669
decreased susceptibility to type IV hypersensitivity reaction J:106669
enlarged spleen J:106669
impaired macrophage chemotaxis J:89125
impaired neutrophil recruitment J:89125
increased leukocyte cell number J:106669
increased lymphocyte cell number J:106669
increased neutrophil cell number J:106669
B4galt1tm1Yiw/B4galt1tm1Yiw
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal IgM level J:117891
glomerulonephritis J:117891
increased IgA level J:117891
B4galt5em1(IMPC)Tcp/B4galt5+
(C57BL/6NCrl-B4galt5em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
B4gat1tm1Mifu/B4gat1tm1Mifu
(B6.Cg-B4gat1tm1Mifu)
abnormal lymph node cell ratio J:120722
immune system phenotype J:120722
impaired leukocyte tethering or rolling J:120722
B4gat1tm1Mifu/B4gat1tm1Mifu
Gcnt1tm1Jxm/Gcnt1tm1Jxm

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal leukocyte migration J:120722
abnormal lymph node cell ratio J:120722
decreased susceptibility to type IV hypersensitivity reaction J:120722
impaired leukocyte tethering or rolling J:120722
B9d2/Tgfb1tm1Flv/B9d2/Tgfb1tm1Flv
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
abnormal regulatory T cell physiology J:204761
B9d2/Tgfb1tm1Flv/B9d2/Tgfb1tm1Flv
Tg(CD207-cre)1Dhka/?

(involves: 129S6/SvEvTac * C57BL/6J * SJL/J)
decreased Langerhans cell number J:126147
B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ)
immune system phenotype J:169839
increased regulatory T cell number J:169839
B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal inflammatory response J:123547
abnormal interferon level J:123547
abnormal interleukin level J:123547
abnormal T cell activation J:123547
abnormal T cell differentiation J:123547
abnormal T-helper 17 cell differentiation J:169839
colitis J:123547
decreased susceptibility to experimental autoimmune encephalomyelitis J:123547
increased anti-double stranded DNA antibody level J:123547
increased anti-nuclear antigen antibody level J:123547
increased T cell proliferation J:123547
B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129S6/SvEvTac * 129X1/SvJ)
abnormal T cell differentiation J:169839
colitis J:169839
decreased susceptibility to experimental autoimmune encephalomyelitis J:169839
decreased T-helper 17 cell number J:169839
increased regulatory T cell number J:169839
increased T-helper 1 cell number J:169839
liver inflammation J:169839
lung inflammation J:169839
B9d2/Tgfb1tm1Flv/B9d2/Tgfb1tm1Flv
Tg(Cd4-cre)1Cwi/?

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal inflammatory response J:123547
B9d2/Tgfb1tm1Flv/B9d2/Tgfb1tm1Flv
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
abnormal regulatory T cell physiology J:204761
B9d2/Tgfb1tm1Flv/B9d2/Tgfb1tm1Flv
Tg(CD207-cre)1Dhka/?

(involves: 129S6/SvEvTac * C57BL/6J * SJL/J)
decreased Langerhans cell number J:126147
B9d2/Tgfb1tm1Flv/B9d2+
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ)
immune system phenotype J:169839
increased regulatory T cell number J:169839
B9d2/Tgfb1tm1Flv/B9d2+
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal T-helper 17 cell differentiation J:169839
B9d2/Tgfb1tm1Flv/B9d2+
Tg(CD207-cre)1Dhka/?

(involves: 129S6/SvEvTac * C57BL/6J * SJL/J)
decreased Langerhans cell number J:126147
B9d2/Tgfb1tm1Flv/B9d2+
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129S6/SvEvTac * 129X1/SvJ)
abnormal T cell differentiation J:169839
colitis J:169839
decreased susceptibility to experimental autoimmune encephalomyelitis J:169839
decreased T-helper 17 cell number J:169839
increased regulatory T cell number J:169839
increased T-helper 1 cell number J:169839
liver inflammation J:169839
lung inflammation J:169839
B9d2tm1a(EUCOMM)Wtsi/B9d2tm1a(EUCOMM)Wtsi
(C57BL/6N-B9d2tm1a(EUCOMM)Wtsi/Wtsi)
abnormal thymus topology J:239583
accessory spleen J:239583
blood in lymph vessels J:239583
enlarged lymphatic vessel J:239583
small spleen J:239583
Baa1BALB/cJ/Baa1NZW/LacJ
(involves: BALB/cJ * NZW/LacJ)
increased IgM level J:35434
Baa2BALB/cJ/Baa2NZW/LacJ
(involves: BALB/cJ * NZW/LacJ)
increased IgM level J:35434
Baatem1(IMPC)Mbp/Baatem1(IMPC)Mbp
(C57BL/6NCrl-Baatem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
Babam1em1(IMPC)Ccpcz/Babam1em1(IMPC)Ccpcz
(C57BL/6NCrl-Babam1em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
decreased CD4-positive NK T cell number J:211773
decreased NK T cell number J:211773
enlarged thymus J:211773
increased eosinophil cell number J:211773
Bach2M1Btlr/Bach2M1Btlr
(C57BL/6J-Bach2M1Btlr)
decreased CD4-positive, alpha-beta T cell number J:272023
increased B-1 B cell number J:272023
Bach2m1Ccg/Bach2m1Ccg
(C57BL/6-Bach2m1Ccg)
decreased B cell number J:94077
decreased marginal zone B cell number J:94077
myeloid hyperplasia J:94077
Bach2m2Anu/Bach2m2Anu
(C57BL/6NCrlAnu-Bach2m2Anu)
decreased mature B cell number J:104190
increased IgM level J:104190
increased immature B cell number J:104190
Bach2tm1a(EUCOMM)Wtsi/Bach2tm1a(EUCOMM)Wtsi
(C57BL/6N-Bach2tm1a(EUCOMM)Wtsi/Wtsi)
decreased B cell number J:211773
decreased CD8-positive, naive alpha-beta T cell number J:211773
decreased CD11b-high dendritic cell number J:211773
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased follicular B cell number J:211773
decreased mature B cell number J:211773
decreased memory-marker NK cell number J:211773
decreased regulatory T cell number J:211773
increased CD4-positive, alpha-beta memory T cell number J:211773
increased CD8-positive, alpha-beta memory T cell number J:211773
increased CD11b-low dendritic cell number J:211773
increased CD103-positive CD11b-low dendritic cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased eosinophil cell number J:211773
increased immature B cell number J:211773
increased KLRG1+ CD4 alpha-beta T cell number J:211773
increased KLRG1+ CD8 alpha-beta T cell number J:211773
increased KLRG1-positive CD4-negative NK T cell number J:211773
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased KLRG1-positive gamma-delta T cell number J:211773
increased KLRG1-positive NK cell number J:211773
increased Ly6C high monocyte number J:211773
increased Ly6C low monocyte number J:211773
increased macrophage cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased memory-marker CD4-negative NK T cell number J:211773
increased memory-marker NK cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased NK cell number J:211773
Bach2tm1b(EUCOMM)Wtsi/Bach2tm1b(EUCOMM)Wtsi
(C57BL/6N-Bach2tm1b(EUCOMM)Wtsi/Ieg)
decreased B cell number J:211773
decreased B-1a cell number J:211773
decreased B-2 B cell number J:211773
decreased CD4-negative NK T cell number J:211773
decreased CD8-positive, naive alpha-beta T cell number J:211773
decreased CD11b-high dendritic cell number J:211773
decreased follicular B cell number J:211773
decreased Ly6C-positive immature NK cell number J:211773
decreased Ly6C-positive mature NK cell number J:211773
decreased marginal zone B cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
decreased NK cell number J:211773
decreased NK T cell number J:211773
decreased transitional stage B cell number J:211773
immune system phenotype J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased eosinophil cell number J:211773
increased granulocyte number J:211773
increased memory-marker CD4-negative NK T cell number J:211773
increased monocyte cell number J:211773
increased NK T cell number J:211773
Bach2tm1Igar/Bach2tm1Igar
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell differentiation J:91110
abnormal B cell physiology J:91110
abnormal class switch recombination J:91110
abnormal somatic hypermutation frequency J:91110
absent germinal center B cells J:91110
decreased B cell number J:91110
decreased IgA level J:91110
decreased IgG1 level J:91110
decreased IgG2a level J:91110
decreased IgG2b level J:91110
decreased IgG3 level J:91110
decreased IgG level J:91110
decreased mature B cell number J:91110
increased IgM level J:91110
spleen hypoplasia J:91110
Badtm1Meg/Badtm1Meg
(involves: 129S4/SvJae)
abnormal B cell differentiation J:88139
abnormal T cell differentiation J:88139
decreased mature B cell number J:88139
decreased pro-B cell number J:88139
decreased thymus weight J:88139
small thymus J:88139
thymus hypoplasia J:88139
Badtm1Sjk/Badtm1Sjk
(either: 129X1/SvJ or (involves: 129X1/SvJ * C57BL/6))
abnormal B cell physiology J:84987
abnormal immune system cell morphology J:84987
abnormal T cell physiology J:84987
Badtm1Sjk/Badtm1Sjk
(involves: 129X1/SvJ)
immune system phenotype J:132819
Bag3tm1.1Jhl/Bag3tm1.1Jhl
(B6.129S2-Bag3tm1.1Jhl)
decreased leukocyte cell number J:144416
decreased lymphocyte cell number J:144416
decreased neutrophil cell number J:144416
decreased spleen weight J:144416
decreased thymus weight J:144416
spleen hypoplasia J:144416
thymus hypoplasia J:144416
Bag4tm1Yeh/Bag4tm1Yeh
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:83559
increased circulating interleukin-6 level J:83559
increased inflammatory response J:83559
increased interleukin-6 secretion J:83559
spleen hypoplasia J:83559
thymus hypoplasia J:83559
Bahd1tm1.1Ics/Bahd1+
(involves: C57BL/6)
decreased susceptibility to bacterial infection J:169470
Bahd1tm2b(KOMP)Wtsi/Bahd1+
(C57BL/6N-Bahd1tm2b(KOMP)Wtsi/Ics)
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased CD4-negative NK T cell number J:211773
increased memory-marker CD4-negative NK T cell number J:211773
increased neutrophil cell number J:211773
increased NK cell number J:211773
increased NK T cell number J:211773
increased T cell number J:211773
Bak1tm1Thsn/Bak1tm1Thsn
Baxtm1Sjk/Baxtm1Sjk

(involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6)
abnormal B cell morphology J:66872
abnormal splenocyte physiology J:66872
abnormal T cell morphology J:66872
enlarged lymph nodes J:66872
enlarged spleen J:66872
increased leukocyte cell number J:66872
increased lymphocyte cell number J:66872
increased spleen red pulp amount J:66872
increased spleen white pulp amount J:66872
Bak1tm1Thsn/Bak1tm1Thsn
Baxtm1Sjk/Baxtm2Sjk
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
abnormal B cell number J:100463
abnormal B cell physiology J:100463
decreased marginal zone B cell number J:100463
increased B cell number J:100463
increased B-2 B cell number J:100463
increased follicular B cell number J:100463
increased IgA level J:100463
increased IgG level J:100463
increased IgM level J:100463
increased immunoglobulin level J:100463
increased pre-B cell number J:100463
increased pro-B cell number J:100463
increased transitional stage B cell number J:100463
Bak1tm1Thsn/Bak1tm1Thsn
Baxtm1Sjk/Baxtm2Sjk
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal T cell differentiation J:100463
arthritis J:100463
glomerulonephritis J:100463
increased anti-double stranded DNA antibody level J:100463
increased B cell number J:100463
increased leukocyte cell number J:100463
increased lymphocyte cell number J:100463
increased susceptibility to autoimmune disorder J:100463
Bak1tm1Thsn/Bak1tm1Thsn
Baxtm2Sjk/Baxtm2Sjk
Tg(Lck-cre)1Cwi/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
decreased thymocyte apoptosis J:220951
Bak1tm1Thsn/Bak1tm1Thsn
Baxtm2Sjk/Baxtm2Sjk
Tg(Lck-cre)548Jxm/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
increased regulatory T cell number J:208318
Bank1tm1Kuro/Bank1tm1Kuro
(Not Specified)
abnormal B cell physiology J:113321
abnormal lymphocyte physiology J:113321
abnormal spleen germinal center morphology J:113321
abnormal splenic cell ratio J:113321
increased B cell proliferation J:113321
increased B-1a cell number J:113321
increased IgG2a level J:113321
increased IgM level J:113321
increased mature B cell number J:113321
increased spleen germinal center number J:113321
increased spleen germinal center size J:113321
Bank1tm1Kuro/Bank1tm1Kuro
Cd40tm1Kik/Cd40tm1Kik

(involves: 129P2/OlaHsd)
immune system phenotype J:113321
Bap1tm1.1Geno/Bap1tm1.1Geno
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NTac)
abnormal granulocyte morphology J:187380
abnormal myelopoiesis J:187380
abnormal neutrophil morphology J:187380
enlarged spleen J:187380
heart inflammation J:187380
increased leukocyte cell number J:187380
increased monocyte cell number J:187380
increased neutrophil cell number J:187380
myeloid hyperplasia J:187380
Batf2tm1Kmm/Batf2tm1Kmm
(129S6/SvEvTac-Batf2tm1Kmm)
increased susceptibility to parasitic infection induced morbidity/mortality J:101977
Batf3tm1Kmm/Batf3tm1Kmm
(involves: 129S6/SvEvTac * BALB/cJ)
abnormal cytotoxic T cell physiology J:141064
abnormal dendritic cell antigen presentation J:141064
abnormal dendritic cell differentiation J:141064
abnormal dendritic cell physiology J:141064
abnormal immune system physiology J:141064
decreased cytotoxic T cell cytolysis J:141064
decreased memory T cell number J:141064
decreased myeloid dendritic cell number J:141064
Batf3tm1Kmm/Batf3tm1Kmm
(involves: 129S6/SvEvTac)
abnormal cytotoxic T cell physiology J:181366
immune system phenotype J:181366
Batf3tm1Kmm/Batf3tm1Kmm
Id2tm1Gtbz/Id2tm1Gtbz

(B6.Cg-Batf3tm1Kmm Id2tm1Gtbz)
abnormal dendritic cell physiology J:194760
Batftm1.1Ejt/Batftm1.1Ejt
(involves: 129S/Sv * C57BL/6 * FVB/N)
abnormal class switch recombination J:160935
abnormal T-helper 2 cell differentiation J:160935
absent germinal center B cells J:160935
decreased CD4-positive, alpha-beta T cell number J:160935
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:160935
decreased IgA level J:160935
decreased IgE level J:160935
decreased IgG1 level J:160935
decreased IgG2c level J:160935
decreased IgM level J:160935
decreased interleukin-4 secretion J:160935
decreased interleukin-17 secretion J:160935
decreased T follicular helper cell number J:160935
decreased T-helper 17 cell number J:160935
Batftm1.1Kmm/Batftm1.1Kmm
(129S6/SvEvTac-Batftm1.1Kmm)
abnormal CD4-positive T cell differentiation J:150643
decreased interleukin-17 secretion J:150643
decreased interleukin-21 secretion J:150643
decreased susceptibility to experimental autoimmune encephalomyelitis J:150643
Baxtm1Sjk/Baxtm1Sjk
(involves: 129X1/SvJ)
enlarged spleen J:29253
increased B cell number J:29253
increased thymocyte number J:29253
Baz2aem1(IMPC)Tcp/Baz2aem1(IMPC)Tcp
(C57BL/6NCrl-Baz2aem1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Baz2bem1(IMPC)Wtsi/Baz2bem1(IMPC)Wtsi
(C57BL/6N-Baz2bem1(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Bbaa1C3H/HeNCr/Bbaa1C3H/HeNCr
(involves: C3H/HeNCr * C57BL/6NCr)
abnormal inflammatory response J:52017
Bbaa1C3H/HeNCr/Bbaa1C57BL/6NCr
(involves: C3H/HeNCr * C57BL/6NCr)
abnormal inflammatory response J:52017
Bbaa2C3H/HeNCr/Bbaa2C3H/HeNCr
(involves: C3H/HeNCr * C57BL/6NCr)
abnormal immune system physiology J:52017
Bbaa3C3H/HeNCr/Bbaa3C3H/HeNCr
(involves: C3H/HeNCr * C57BL/6NCr)
abnormal inflammatory response J:73060
Bbaa3C3H/HeNCr/Bbaa3C57BL/6NCr
(involves: C3H/HeNCr * C57BL/6NCr)
abnormal inflammatory response J:52017
Bbaa5C57BL/6NCr/Bbaa5C57BL/6NCr
(involves: C3H/HeNCr * C57BL/6NCr)
increased IgM level J:52017
Bbaa9C57BL/6NCr/Bbaa9C3H/HeNCr
(involves: C3H/HeNCr * C57BL/6NCr)
abnormal immunoglobulin level J:52017
Bbaa9C57BL/6NCr/Bbaa9C57BL/6NCr
(involves: C3H/HeNCr * C57BL/6NCr)
abnormal immunoglobulin level J:52017
Bbaa10C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa11C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa12C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa13C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa14C3H/HeJ/?
(involves: C3H/HeN * C57BL/6N)
increased IgG level J:73060
increased inflammatory response J:73060
Bbaa15C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased IgG level J:73060
Bbaa16C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa17C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa18C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa19C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased IgG level J:73060
Bbaa20C3H/HeJ/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa21C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased susceptibility to bacterial infection J:73060
Bbaa22C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbaa23C3H/HeN/?
(involves: C3H/HeN * C57BL/6N)
increased inflammatory response J:73060
Bbc3tm1Ast/Bbc3tm1Ast
(involves: C57BL/6 * NZB)
abnormal CD8-positive, alpha-beta T cell physiology J:132819
abnormal splenic cell ratio J:132819
immune system phenotype J:132819
increased CD8-positive, alpha-beta T cell number J:132819
increased leukocyte cell number J:132819
Bbc3tm1Gpz/Bbc3tm1Gpz
Trp53tm1Brd/Trp53tm8Xu

(involves: 129P2/OlaHsd * 129S7/SvEvBrd)
decreased thymocyte number J:170216
Bblntm1(KOMP)Wtsi/Bbln+
(involves: C57BL/6N)
abnormal osteoclast differentiation J:296689
Bblntm1(KOMP)Wtsi/Bblntm1(KOMP)Wtsi
(involves: C57BL/6N)
abnormal osteoclast differentiation J:296689
increased osteoclast cell number J:296689
Bbs4Gt1Nk/Bbs4Gt1Nk
(involves: 129S7/SvEvBrd)
increased immunoglobulin level J:134093
Bbs5tm1b(EUCOMM)Wtsi/Bbs5tm1b(EUCOMM)Wtsi
(C57BL/6NTac-Bbs5tm1b(EUCOMM)Wtsi/H)
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Bbs12em1(IMPC)Ccpcz/Bbs12+
(C57BL/6NCrl-Bbs12em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Bbs12tm1.1Vmar/Bbs12tm1.1Vmar
(involves: 129S6/SvEvTac * C57BL/6)
decreased circulating interleukin-6 level J:189019
decreased circulating tumor necrosis factor level J:189019
decreased inflammatory response J:189019
Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
(involves: C57BL/6 * C57BL/6N)
increased IgA level J:213427
Bcap31tm1.1Bwang/Bcap31tm1.1Bwang
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
increased inflammatory response J:292505
increased interleukin-1 beta secretion J:292505
increased microglial cell activation J:292505
increased tumor necrosis factor secretion J:292505
Bcap31tm1.1Bwang/Bcap31tm1.1Bwang
Tg(Lck-cre)548Jxm/0

(involves: C57BL/6 * CBA)
abnormal T cell activation J:274469
decreased CD8-positive, naive alpha-beta T cell number J:274469
decreased interferon-gamma secretion J:274469
decreased interleukin-2 secretion J:274469
decreased single-positive T cell number J:274469
decreased T cell proliferation J:274469
decreased thymocyte number J:274469
decreased thymus weight J:274469
increased effector memory T-helper cell number J:274469
increased thymocyte apoptosis J:274469
small thymus J:274469
thymus hypoplasia J:274469
Bcar3em1(IMPC)Mbp/Bcar3em1(IMPC)Mbp
(C57BL/6N-Bcar3em1(IMPC)Mbp/MbpMmucd)
increased basophil cell number J:211773
Bcas1tm1Himo/Bcas1tm1Himo
(C57BL/6-Bcas1tm1Himo)
brain inflammation J:242041
Bcat1tm1.2Eaa/Bcat1tm1.2Eaa
(involves: C57BL/6)
abnormal T cell physiology J:216027
Bckdhaem1(IMPC)Tcp/Bckdha+
(C57BL/6NCrl-Bckdhaem1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Bcl2tm1Dlo/Bcl2tm1Dlo
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:73660
decreased CD8-positive, alpha-beta T cell number J:73660
decreased lymphocyte cell number J:73660
decreased mature B cell number J:73660
decreased pre-B cell number J:73660
decreased thymocyte number J:73660
Bcl2tm1Dlo/Bcl2tm1Dlo
(B6.129P2-Bcl2tm1Dlo)
abnormal leukopoiesis J:73316
abnormal lymphocyte physiology J:104487, J:73316
decreased spleen weight J:153846
decreased spleen white pulp amount J:153846
increased B cell apoptosis J:73316
increased splenocyte apoptosis J:153846
increased T cell apoptosis J:73316
spleen atrophy J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Ast/Bcl2l11+

(B6.129-Bcl2tm1Dlo Bcl2l11tm1.1Ast)
abnormal lymphocyte physiology J:73316
increased T cell apoptosis J:73316
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Ast/Bcl2l11+

(B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Ast)
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast

(B6.129-Bcl2tm1Dlo Bcl2l11tm1.1Ast)
abnormal leukopoiesis J:73316
abnormal lymphocyte physiology J:73316
decreased B cell apoptosis J:73316
increased T cell apoptosis J:73316
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast

(B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Ast)
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Boui/Bcl2l11tm1.1Boui

(B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Boui)
immune system phenotype J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui

(B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui)
immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm2.1Boui/Bcl2l11tm2.1Boui

(B6.Cg-Bcl2tm1Dlo Bcl2l11tm2.1Boui)
immune system phenotype J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm3.1Boui/Bcl2l11tm3.1Boui

(B6.Cg-Bcl2tm1Dlo Bcl2l11tm3.1Boui)
decreased splenocyte apoptosis J:153846
immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2tm1Dlo/Bcl2tm1Dlo
Biktm1Ast/Biktm1Ast

(B6.Cg-Bcl2tm1Dlo Biktm1Ast)
abnormal lymphocyte physiology J:104487
Bcl2tm1Irt/Bcl2tm1Irt
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
increased macrophage apoptosis J:144243
Bcl2tm1Lbox/Bcl2tm1Lbox
(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
abnormal B cell activation J:114637
abnormal B cell differentiation J:114637
decreased B cell number J:114637
decreased B cell proliferation J:114637
decreased immature B cell number J:114637
decreased mature B cell number J:114637
decreased pre-B cell number J:114637
increased B cell apoptosis J:114637
Bcl2tm1Sjk/Bcl2tm1Sjk
(involves: 129S2/SvPas * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:15224
abnormal CD8-positive, alpha beta T cell morphology J:15224
abnormal immune system organ morphology J:15224
abnormal spleen morphology J:15224
abnormal spleen red pulp morphology J:15224
abnormal spleen white pulp morphology J:15224
abnormal thymus involution J:15224
abnormal thymus morphology J:15224
decreased B cell number J:15224
decreased double-positive T cell number J:15224
decreased lymphocyte cell number J:15224
decreased T cell number J:15224
increased double-negative T cell number J:15224
increased T cell apoptosis J:15224
small spleen J:15224
small thymus J:15224
Bcl2tm1Tsu/Bcl2tm1Tsu
(involves: 129P2/OlaHsd * ICR)
abnormal lymphocyte morphology J:22391
abnormal T cell physiology J:22391
small spleen J:22391
small thymus J:22391
spleen atrophy J:22391
thymus atrophy J:22391
Bcl2tm2.1Lbox/Bcl2+
(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
abnormal B cell physiology J:175730
enlarged lymph nodes J:175730
enlarged spleen J:175730
increased B cell number J:175730
increased immature B cell number J:175730
increased mature B cell number J:175730
increased pre-B cell number J:175730
Bcl2tm2.1Lbox/Bcl2tm2.1Lbox
(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
abnormal B cell physiology J:175730
enlarged lymph nodes J:175730
enlarged spleen J:175730
increased B cell number J:175730
increased immature B cell number J:175730
increased mature B cell number J:175730
increased pre-B cell number J:175730
Bcl2a1atm1.1Tac/Bcl2a1atm1.1Tac
Bcl2a1btm1.1Tac/Bcl2a1btm1.1Tac
Bcl2a1dtm1.1Tac/Bcl2a1dtm1.1Tac

(involves: BALB/cJ * C57BL/6NTac)
abnormal dendritic cell physiology J:258915
decreased CD4-positive, alpha-beta memory T cell number J:258915
decreased central memory CD4-positive, alpha-beta T cell number J:258915
decreased dendritic cell number J:258915
decreased effector memory CD4-positive, alpha-beta T cell number J:258915
decreased gamma-delta T cell number J:258915
decreased regulatory T cell number J:258915
immune system phenotype J:258915
Bcl2a1atm1Prys/Bcl2a1atm1Prys
(involves: 129/Sv * C57BL/6J * SJL)
abnormal neutrophil physiology J:74478
decreased inflammatory response J:74478
decreased susceptibility to parasitic infection J:74478
Bcl2a1atm1Sen/Bcl2a1atm1Sen
(involves: 129P2/OlaHsd * C57BL/6)
abnormal neutrophil physiology J:52127
Bcl2l1tm1Cant/Bcl2l1tm1Cant
(involves: 129S6/SvEvTac)
abnormal memory T cell physiology J:77507
abnormal T cell physiology J:77507
decreased interleukin-2 secretion J:77507
decreased memory T cell number J:77507
decreased susceptibility to experimental autoimmune encephalomyelitis J:77507
decreased T cell proliferation J:77507
Bcl2l1tm1Dlo/Bcl2l1tm1.1Mam
Tg(Aicda-cre)9Mbu/0

(B6.Cg-Bcl2l1tm1Dlo/Bcl2l1tm1.1Mam Tg(Aicda-cre)9Mbu)
decreased IgG1 level J:166069
immune system phenotype J:166069
Bcl2l1tm1Ywh/Bcl2l1tm1Ywh
Mcl1tm1Ywh/Mcl1tm1Ywh
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
absent CD4-positive, alpha-beta T cells J:137400
absent CD8-positive, alpha-beta T cells J:137400
decreased double-positive T cell number J:137400
Bcl2l1tm1Ywh/Bcl2l1tm1Ywh
Tg(Lck-cre)548Jxm/?

(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA)
decreased double-positive T cell number J:99012
decreased thymocyte number J:99012
Bcl2l11em1(IMPC)H/Bcl2l11em1(IMPC)H
(C57BL/6NTac-Bcl2l11em1(IMPC)H/H)
increased large unstained cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased spleen weight J:211773
Bcl2l11em1Flv/Bcl2l11+
Morrbid+/Morrbidem1Flv

(C57BL/6N-Bcl2l11em1Flv +/+ Morrbidem1Flv)
decreased eosinophil cell number J:236609
decreased Ly6C high monocyte number J:236609
decreased neutrophil cell number J:236609
Bcl2l11em1Flv/Bcl2l11+
Morrbidem1Flv/Morrbid+

(C57BL/6N-Bcl2l11em1Flv Morrbidem1Flv /+ +)
immune system phenotype J:236609
Bcl2l11tm1.1Ast/Bcl2l11+
(involves: 129S1/Sv * C57BL/6)
abnormal lymphocyte physiology J:58641
glomerulonephritis J:58641
increased IgA level J:58641
increased IgG level J:58641
increased IgM level J:58641
increased susceptibility to autoimmune disorder J:58641
Bcl2l11tm1.1Ast/Bcl2l11+
(B6.129S1-Bcl2l11tm1.1Ast)
immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2l11tm1.1Ast/Bcl2l11+
Ptentm1Hwu/Pten+
Tg(CD2-icre)4Kio/0

(involves: 129S1/Sv * 129S4/SvJae * C57BL/10 * CBA/Ca)
abnormal T cell number J:133215
increased germinal center B cell number J:133215
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
(involves: 129S1/Sv * C57BL/6)
abnormal B cell proliferation J:90963
abnormal lymphocyte physiology J:58641
abnormal plasma cell morphology J:58641
abnormal spleen morphology J:58641
abnormal splenic cell ratio J:132217
decreased B cell apoptosis J:90963
decreased double-positive T cell number J:58641
enlarged spleen J:58641
glomerulonephritis J:58641
increased anti-double stranded DNA antibody level J:132217
increased anti-histone antibody level J:132217
increased anti-nuclear antigen antibody level J:132217
increased anti-single stranded DNA antibody level J:132217
increased autoantibody level J:132217
increased B cell number J:58641
increased CD4-positive, alpha-beta T cell number J:58641
increased CD8-positive, alpha-beta T cell number J:58641
increased double-negative T cell number J:58641
increased follicular B cell number J:132217
increased granulocyte number J:58641
increased IgA level J:58641
increased IgG level J:58641
increased IgM level J:58641
increased immature B cell number J:132217
increased inflammatory response J:58641
increased leukocyte cell number J:58641
increased marginal zone B cell number J:132217
increased monocyte cell number J:58641
increased splenocyte number J:132217
increased susceptibility to autoimmune disorder J:58641
increased T cell number J:58641
increased transitional stage B cell number J:132217
spleen hyperplasia J:58641
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
(B6.129S1-Bcl2l11tm1.1Ast)
abnormal B cell morphology J:133084
abnormal leukopoiesis J:73316
abnormal lymphocyte physiology J:73316
abnormal NK cell morphology J:123409
abnormal response to infection J:123409
decreased B cell apoptosis J:73316
decreased T cell apoptosis J:73316, J:133084
immune system phenotype J:153846
increased immature B cell number J:133084
increased leukocyte cell number J:153846
increased mature B cell number J:133084
increased NK cell number J:123409
increased regulatory T cell number J:208318
increased spleen weight J:153846
increased transitional stage B cell number J:133084
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
(B6.129-Bcl2l11tm1.1Ast/J)
decreased lymphocyte cell number J:137609
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
(involves: 129S1/Sv)
abnormal CD4-positive, alpha-beta T cell number J:132819
abnormal CD8-positive, alpha-beta T cell physiology J:132819
abnormal splenic cell ratio J:132819
decreased splenocyte apoptosis J:266833
decreased thymocyte apoptosis J:266833
increased B cell number J:132819
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
(B6.129S1-Bcl2l11tm1.1Ast/J)
decreased T cell apoptosis J:153652
increased B cell number J:153652
increased CD4-positive, alpha-beta T cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Biktm1Ast/Biktm1Ast

(B6.Cg-Bcl2l11tm1.1Ast Biktm1Ast)
abnormal B cell differentiation J:103605
abnormal lymphocyte physiology J:103605
abnormal T cell differentiation J:103605
decreased immature B cell number J:103605
decreased pre-B cell number J:103605
decreased pro-B cell number J:103605
enlarged spleen J:103605
increased B cell number J:103605
increased granulocyte number J:103605
increased mature B cell number J:103605
increased monocyte cell number J:103605
increased T cell number J:103605
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Bmftm1Rjd/Bmftm1Rjd

(B6.129S-Bcl2l11tm1.1Ast Bmftm1Rjd)
decreased T cell apoptosis J:153652
increased B cell number J:153652
increased CD4-positive, alpha-beta T cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
increased thymocyte number J:153652
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Bmftm2.1Rjd/Bmftm2.1Rjd

(B6.129S-Bcl2l11tm1.1Ast Bmftm2.1Rjd)
increased B cell number J:153652
increased CD4-positive, alpha-beta T cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Bnip3lGt(XT0573)Wtsi/Bnip3lGt(XT0573)Wtsi

(involves: 129S1/Sv * C57BL/6)
decreased lymphocyte cell number J:137609
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Dicer1tm1Mmk/Dicer1tm1Mmk
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S1/Sv * BALB/c)
decreased B cell number J:135783
decreased mature B cell number J:135783
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Faslpr/Faslpr

(B6.Cg-Bcl2l11tm1.1Ast Faslpr)
abnormal effector T cell morphology J:132217
abnormal lymph node cell ratio J:132217
abnormal splenic cell ratio J:132217
abnormal T cell number J:132217
abnormal T cell subpopulation ratio J:132217
decreased B cell number J:132217
decreased spleen red pulp amount J:132217
enlarged lymph nodes J:132217
enlarged spleen J:132217
increased anti-double stranded DNA antibody level J:132217
increased anti-histone antibody level J:132217
increased anti-nuclear antigen antibody level J:132217
increased anti-single stranded DNA antibody level J:132217
increased autoantibody level J:132217
increased dendritic cell number J:132217
increased follicular B cell number J:132217
increased immature B cell number J:132217
increased leukocyte cell number J:132217
increased macrophage cell number J:132217
increased marginal zone B cell number J:132217
increased memory T cell number J:132217
increased spleen white pulp amount J:132217
increased susceptibility to autoimmune disorder J:132217
increased transitional stage B cell number J:132217
lymph node hyperplasia J:132217
spleen hyperplasia J:132217
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Il15tm1Imx/Il15tm1Imx

(involves: C57BL/6)
immune system phenotype J:208318
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Mirc14tm1.2Flv/Mirc14tm1.2Flv

(involves: 129S1/Sv * C57BL/6 * C57BL/6N * FVB/N * SJL)
decreased NK T cell number J:203157
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Mlf1tm1Swm/Mlf1tm1Swm

(involves: 129S1/Sv * C57BL/6)
decreased splenocyte apoptosis J:266833
decreased thymocyte apoptosis J:266833
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Pmaip1tm1Ast/Pmaip1tm1Ast

(involves: 129S1/Sv * C57BL/6)
abnormal NK cell morphology J:123409
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Zbtb1m1Btlr/Zbtb1m1Btlr

(involves: 129S1/Sv * C3H/HeN * C57BL/6 * C57BL/6J)
absent T cells J:178820
Bcl2l11tm1.1Boui/Bcl2l11+
Tg(IghMyc)22Bri/0

(involves: C57BL/6 * SJL)
increased leukocyte cell number J:186117
Bcl2l11tm1.1Boui/Bcl2l11tm1.1Boui
(C57BL/6-Bcl2l11tm1.1Boui)
immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2l11tm1.1Boui/Bcl2l11tm1.1Boui
Tg(IghMyc)22Bri/0

(involves: C57BL/6 * SJL)
increased leukocyte cell number J:186117
Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui
(C57BL/6-Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui)
immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2l11tm1Ast/Bcl2l11tm1Ast
Dicer1tm1Bdh/Dicer1tm1Bdh
Aicdatm1(cre)Njen/Aicda+

(involves: 129S1/Sv * C57BL/6)
abnormal B cell differentiation J:181782
decreased germinal center B cell number J:181782
decreased plasma cell number J:181782
Bcl2l11tm1Sjk/Bcl2l11tm1Sjk
(involves: 129X1/SvJ)
abnormal B cell physiology J:100463
abnormal spleen marginal zone morphology J:100463
increased B cell number J:100463
increased B-2 B cell number J:100463
increased follicular B cell number J:100463
increased immunoglobulin level J:100463
increased transitional stage B cell number J:100463
Bcl2l11tm2.1Boui/Bcl2l11+
Tg(IghMyc)22Bri/0

(involves: C57BL/6 * SJL)
increased leukocyte cell number J:186117
Bcl2l11tm2.1Boui/Bcl2l11tm2.1Boui
(C57BL/6-Bcl2l11tm2.1Boui)
immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2l11tm2.1Boui/Bcl2l11tm2.1Boui
Tg(IghMyc)22Bri/0

(involves: C57BL/6 * SJL)
increased leukocyte cell number J:186117
Bcl2l11tm3.1Boui/Bcl2l11tm3.1Boui
(C57BL/6-Bcl2l11tm3.1Boui)
immune system phenotype J:153846
increased leukocyte cell number J:153846
increased spleen weight J:153846
Bcl2l11tm3Rjd/Bcl2l11tm3Rjd
(B6.129S6-Bcl2l11tm3Rjd)
decreased thymocyte apoptosis J:137061
increased B cell number J:153652
increased CD4-positive, alpha-beta T cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
Bcl2l11tm3Rjd/Bcl2l11tm3Rjd
Bmftm3.1Rjd/Bmftm3.1Rjd

(B6.129S6-Bcl2l11tm3Rjd Bmftm3.1Rjd)
increased B cell number J:153652
increased CD4-positive, alpha-beta T cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
Bcl2l11tm4Boul/Bcl2l11tm4Boul
(involves: C57BL/6)
immune system phenotype J:203181
Bcl2l11tm4Rjd/Bcl2l11tm4Rjd
(involves: 129S6/SvEvTac * C57BL/6)
immune system phenotype J:203181
Bcl2l11tm5Boul/Bcl2l11tm5Boul
(involves: C57BL/6)
immune system phenotype J:203181
Bcl2l11tm6.1Boui/Bcl2l11tm6.1Boui
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
increased regulatory T cell number J:208318
Bcl2l12tm1.1(KOMP)Vlcg/Bcl2l12tm1.1(KOMP)Vlcg
(C57BL/6N-Bcl2l12tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Bcl2l14tm1.1Boui/Bcl2l14tm1.1Boui
(involves: C57BL/6)
abnormal susceptibility to induced colitis J:296081
Bcl3m1Btlr/Bcl3+
(C57BL/6J-Bcl3m1Btlr)
decreased B cell number J:255184
decreased B-1b cell number J:255184
increased CD8-positive, alpha-beta T cell number J:255184
increased macrophage cell number J:255184
Bcl3m1Btlr/Bcl3m1Btlr
(C57BL/6J-Bcl3m1Btlr)
abnormal humoral immune response J:255184
decreased B cell number J:255184
decreased B-1b cell number J:255184
decreased IgE level J:255184
decreased IgG level J:255184
increased B-1 B cell number J:255184
increased CD8-positive, alpha-beta T cell number J:255184
increased central memory CD4-positive, alpha-beta T cell number J:255184
increased macrophage cell number J:255184
Bcl3m2Btlr/Bcl3m2Btlr
(C57BL/6J-Bcl3m2Btlr)
decreased CD4-positive, alpha-beta T cell number J:264818
decreased IgD level J:264818
increased B-1 B cell number J:264818
increased CD8-positive, alpha-beta memory T cell number J:264818
increased IgM level J:264818
Bcl3m3Btlr/Bcl3m3Btlr
(C57BL/6J-Bcl3m3Btlr)
decreased central memory CD8 positive, alpha-beta T cell number J:274858
Bcl3tm1b(EUCOMM)Wtsi/Bcl3tm1b(EUCOMM)Wtsi
(C57BL/6N-Bcl3tm1b(EUCOMM)Wtsi/H)
increased spleen weight J:211773
Bcl3tm1Rie/Bcl3tm1Rie
(involves: 129)
abnormal dendritic cell number J:77049
abnormal follicular dendritic cell morphology J:77049
abnormal myeloid dendritic cell morphology J:77049
abnormal Peyer's patch follicle morphology J:77049
abnormal Peyer's patch germinal center morphology J:77049
abnormal Peyer's patch morphology J:77049
abnormal Peyer's patch T cell area morphology J:77049
decreased B cell number J:77049
decreased Peyer's patch number J:77049
increased plasmacytoid dendritic cell number J:77049
small Peyer's patches J:77049
Bcl3tm1Rsch/Bcl3tm1Rsch
(involves: 129P2/OlaHsd * CD-1)
abnormal cytokine secretion J:116724
abnormal innate immunity J:116724
increased susceptibility to bacterial infection J:116724
Bcl3tm1Rsch/Bcl3tm1Rsch
(B6.Cg-Bcl3tm1Rsch)
abnormal cytokine secretion J:116724
abnormal macrophage physiology J:116724
Bcl3tm1Sbn/Bcl3tm1Sbn
(involves: 129S4/SvJae * C57BL/6)
abnormal B cell differentiation J:39747
abnormal class switch recombination J:39747
abnormal cytotoxic T cell physiology J:39747
abnormal lymph node B cell domain morphology J:39747
abnormal lymphocyte morphology J:39747
abnormal metallophilic macrophage morphology J:39747
abnormal spleen marginal zone macrophage morphology J:39747
absent spleen germinal center J:39747
decreased B cell number J:39747
decreased IgG2a level J:39747
decreased interferon-gamma secretion J:39747
decreased interleukin-12 secretion J:39747
decreased macrophage cell number J:39747
decreased spleen germinal center size J:39747
disorganized spleen B cell follicle J:39747
increased susceptibility to parasitic infection J:39747
intermingled spleen red and white pulp J:39747
lymph node hypoplasia J:39747
Bcl3tm1Sbn/Bcl3tm1Sbn
(involves: 129S4/SvJae)
abnormal B cell physiology J:207111
decreased B cell proliferation J:207111
decreased follicular B cell number J:207111
decreased transitional stage T1 B cell number J:207111
decreased transitional stage T2 B cell number J:207111
increased B cell proliferation J:207111
increased marginal zone B cell number J:207111
Bcl3tm1Ver/Bcl3tm1Ver
(involves: 129P2/OlaHsd * FVB/NJ)
abnormal humoral immune response J:38092
absent spleen germinal center J:38092
immune system phenotype J:38092
increased susceptibility to bacterial infection J:38092
Bcl6tm1.1Dent/Bcl6tm1.1Dent
Tg(Cd4-cre)1Cwi/0

(involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N)
abnormal T follicular helper cell differentiation J:202372
decreased germinal center B cell number J:202372
decreased IgG level J:202372
decreased interleukin-4 secretion J:202372
decreased T follicular helper cell number J:202372
increased interleukin-10 secretion J:202372
Bcl6tm1.1Jwan/Bcl6tm1.1Jwan
(involves: 129S6/SvEvTac)
abnormal somatic hypermutation frequency J:190534
immune system phenotype J:190534
Bcl6tm1.1Meln/Bcl6tm1.1Meln
(involves: 129 * C57BL/6 * FVB/N)
abnormal adaptive immunity J:194821
abnormal germinal center B cell physiology J:194821
abnormal immune system organ morphology J:194821
abnormal Peyer's patch germinal center morphology J:194821
abnormal professional antigen presenting cell physiology J:194821
abnormal spleen germinal center morphology J:194821
decreased IgG1 level J:194821
decreased IgG2a level J:194821
decreased IgG level J:194821
decreased spleen germinal center number J:194821
decreased T follicular helper cell number J:194821
immune system phenotype J:194821
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6 * C57BL/6JJcl)
abnormal humoral immune response J:190943
abnormal memory B cell morphology J:190943
abnormal memory B cell physiology J:190943
abnormal somatic hypermutation frequency J:190943
decreased germinal center B cell number J:190943
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto
Cd79atm1(cre)Reth/Cd79a+
Tg(Cd4-cre)1Cwi/0

(involves: BALB/c * C57BL/6 * C57BL/6JJcl * DBA/2)
decreased germinal center B cell number J:190943
immune system phenotype J:190943
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JJcl)
decreased germinal center B cell number J:190943
immune system phenotype J:190943
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * C57BL/6JJcl * DBA/2)
abnormal humoral immune response J:190943
abnormal somatic hypermutation frequency J:190943
absent germinal center B cells J:190943
decreased germinal center B cell number J:190943
decreased T follicular helper cell number J:190943
Bcl6tm1.1Toka/Bcl6+
Tg(TcraTcrb)425Cbn/0

(involves: BALB/c * C57BL/6 * NZB)
decreased T cell proliferation J:174014
Bcl6tm1.1Toka/Bcl6tm1.1Toka
(involves: C57BL/6 * NZB)
abnormal Peyer's patch morphology J:174014
decreased germinal center B cell number J:174014
decreased T follicular helper cell number J:174014
immune system phenotype J:174014
Bcl6tm1.1Toka/Bcl6tm1.1Toka
Tg(IghelMD4)4Ccg/0

(involves: C57BL/6 * NZB)
abnormal germinal center B cell physiology J:174014
increased activation-induced B cell apoptosis J:174014
Bcl6tm1Gdba/Bcl6tm1Gdba
Tg(Adipoq-cre)1Evdr/0

(involves: C57BL/6 * FVB/NJ)
white adipose tissue inflammation J:271078
Bcl6tm1Htno/Bcl6tm1Htno
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal spleen morphology J:55952
lung inflammation J:55952
myocarditis J:55952
Bcl6tm1Rdf/Bcl6tm1Rdf
(involves: 129S1/Sv)
abnormal B cell physiology J:40769
abnormal humoral immune response J:40769
abnormal immune system morphology J:40769
abnormal immune system physiology J:40769
abnormal Peyer's patch germinal center morphology J:40769
abnormal T-helper 2 physiology J:40769
absent lymph node germinal center J:40769
absent spleen germinal center J:40769
decreased IgG level J:40769
decreased IgM level J:40769
heart inflammation J:40769
increased eosinophil cell number J:40769
increased inflammatory response J:40769
increased susceptibility to bacterial infection J:40769
liver inflammation J:40769
lung inflammation J:40769
small thymus J:40769
spleen hyperplasia J:40769
Bcl6tm1Sdt/Bcl6tm1Sdt
(involves: 129/Sv * C57BL/6)
abnormal chemokine level J:123621
abnormal immune system physiology J:123621
spleen hypoplasia J:123621
Bcl6tm1Sdt/Bcl6tm1Sdt
Bcl6btm2Dent/Bcl6btm2Dent

(involves: 129/Sv * C57BL/6)
abnormal immune system physiology J:123621
Bcl6tm2Rdf/Bcl6tm2Rdf
(involves: 129S1/Sv)
abnormal B cell physiology J:40769
abnormal humoral immune response J:40769
abnormal immune system morphology J:40769
abnormal immune system physiology J:40769
abnormal Peyer's patch germinal center morphology J:40769
abnormal T-helper 2 physiology J:40769
absent lymph node germinal center J:40769
absent spleen germinal center J:40769
decreased B cell proliferation J:40769
decreased IgG level J:40769
decreased IgM level J:40769
heart inflammation J:40769
increased eosinophil cell number J:40769
increased inflammatory response J:40769
increased susceptibility to bacterial infection J:40769
liver inflammation J:40769
lung inflammation J:40769
small thymus J:40769
spleen hyperplasia J:40769
Bcl6tm2Rdf/Bcl6tm2Rdf
Ighmtm1(Bcl6)Rdf/?

(involves: 129/Sv * 129S1/Sv * C57BL/6)
abnormal immune system morphology J:98937
abnormal spleen germinal center morphology J:98937
Bcl6btm1Dtf/Bcl6btm1Dtf
(involves: 129P2/OlaHsd)
abnormal response to infection J:99818
decreased memory T cell number J:99818
decreased T cell proliferation J:99818
Bcl6btm1Tto/Bcl6btm1Tto
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:93656
abnormal CD8-positive, alpha beta T cell morphology J:93656
Bcl6btm2Dent/Bcl6btm2Dent
(involves: 129/Sv * C57BL/6)
decreased neutrophil cell number J:123621
increased monocyte cell number J:123621
Bcl6btm2Dent/Bcl6btm2Dent
Rag1tm1Mom/Rag1tm1Mom

(involves: 129/Sv * 129S7/SvEvBrd * C57BL/6)
decreased lymphocyte cell number J:123621
Bcl10m1Btlr/Bcl10m1Btlr
(C57BL/6J-Bcl10m1Btlr)
abnormal humoral immune response J:265122
decreased B-1 B cell number J:265122
decreased IgG level J:265122
increased CD4-positive, alpha-beta T cell number J:265122
increased IgE level J:265122
increased IgM level J:265122
increased single-positive T cell number J:265122
increased T cell number J:265122
Bcl10tm1Mak/Bcl10tm1Mak
(involves: 129P2/OlaHsd)
abnormal cytotoxic T cell physiology J:67297
abnormal dendritic cell physiology J:111706
abnormal immune cell physiology J:67297
abnormal response to infection J:67297
abnormal T cell activation J:67297
abnormal T cell differentiation J:67297
decreased activated T cell number J:67297
decreased B cell proliferation J:109545, J:67297
decreased double-positive T cell number J:67297
decreased IgG level J:67297
decreased IgM level J:67297
decreased immunoglobulin level J:67297
decreased T cell proliferation J:109545, J:67297
decreased thymocyte number J:67297
increased double-negative T cell number J:67297
increased susceptibility to infection J:67297
Bcl10tm1Mak/Bcl10tm1Mak
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm2(CARD11*L225LI)Jrld/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd)
immune system phenotype J:228288
Bcl10tm1Swm/Bcl10tm1Swm
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:85147
abnormal humoral immune response J:85147
abnormal marginal zone B cell physiology J:85147
decreased B cell number J:85147
decreased B cell proliferation J:85147
decreased B-1 B cell number J:85147
decreased follicular B cell number J:85147
decreased marginal zone B cell number J:85147
decreased mature B cell number J:85147
increased susceptibility to bacterial infection J:85147
Bcl10tm1Swm/Bcl10tm1Swm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:122394
abnormal dendritic cell physiology J:122394
Bcl11atm1Ngc/Bcl11a+
(involves: 129S1/Sv)
abnormal T cell differentiation J:194616
decreased DN2 thymocyte number J:194616
decreased lymphocyte cell number J:207383
Bcl11atm1Ngc/Bcl11atm1Ngc
(involves: 129S1/Sv * C57BL/6J)
abnormal dendritic cell differentiation J:207383
abnormal immunoglobulin heavy chain V(D)J recombination J:83646
absent B cells J:207383, J:83646
absent CD4-positive, alpha-beta T cells J:83646
absent lymphocyte J:207383
decreased plasmacytoid dendritic cell number J:207383
decreased T cell number J:83646
increased CD8-positive, alpha-beta T cell number J:83646
increased double-negative T cell number J:83646
increased gamma-delta T cell number J:83646
small thymus J:83646
thymus hypoplasia J:83646
Bcl11atm1Pwt/Bcl11atm1Pwt
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
decreased B cell number J:207383
decreased circulating interferon-alpha level J:207383
decreased plasmacytoid dendritic cell number J:207383
Bcl11atm1Pwt/Bcl11atm1Pwt
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0

(involves: 129X1/SvJ * C57BL/6 * CBA)
abnormal dendritic cell differentiation J:207383
decreased B cell number J:207383
decreased dendritic cell number J:207383
decreased plasmacytoid dendritic cell number J:207383
Bcl11atm1Pwt/Bcl11atm1Pwt
Kdm1atm1.1Sho/Kdm1atm1.1Sho
Tg(Mx1-cre)1Cgn/0

(involves: 129 * C57BL/6 * CBA)
decreased leukocyte cell number J:196140
Bcl11atm1Pwt/Bcl11atm1Pwt
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
decreased leukocyte cell number J:196140
Bcl11atm2.1Peli/Bcl11atm2.1Peli
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * 129S1/Sv)
abnormal immune system morphology J:194616
abnormal T cell differentiation J:194616
decreased B cell number J:194616
decreased DN2 thymocyte number J:194616
decreased immature B cell number J:194616
decreased pre-B cell number J:194616
decreased pro-B cell number J:194616
increased B cell apoptosis J:194616
Bcl11atm2.1Peli/Bcl11atm2.1Peli
Trp53tm1Brn/Trp53tm1Brn
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * 129S1/Sv)
immune system phenotype J:194616
Bcl11btm1.2Leid/Bcl11btm1.2Leid
(involves: C57BL/6 * SJL)
absent T cells J:147182
thymus hypoplasia J:147182
Bcl11btm1Avram/Bcl11btm1Avram
Tcratm1Mom/Tcratm1Mom
Tg(Cd4-cre)1Cwi/?

(involves: 129 * C57BL/6 * DBA/2)
abnormal positive T cell selection J:128515
decreased double-positive T cell number J:128515
thymus hypoplasia J:128515
Bcl11btm1Avram/Bcl11btm1Avram
Tg(Cd4-cre)1Cwi/?

(involves: 129 * C57BL/6 * DBA/2)
abnormal leukocyte morphology J:128515
abnormal positive T cell selection J:128515
abnormal thymocyte activation J:128515
decreased CD4-positive, alpha-beta T cell number J:128515
decreased CD8-positive, alpha-beta T cell number J:128515
decreased double-negative T cell number J:128515
decreased double-positive T cell number J:128515
enlarged mesenteric lymph nodes J:128515
increased B cell number J:128515
increased dendritic cell number J:128515
increased gamma-delta T cell number J:128515
increased NK cell number J:128515
increased spleen weight J:128515
spleen hyperplasia J:128515
thymus hypoplasia J:128515
Bcl11btm1Avram/Bcl11btm1Avram
Tg(Cd4-cre)1Cwi/?
Tg(LCKprBCL2)36Sjk/?

(involves: 129 * C57BL/6 * DBA/2)
abnormal positive T cell selection J:128515
decreased CD4-positive, alpha-beta T cell number J:128515
decreased CD8-positive, alpha-beta T cell number J:128515
decreased double-positive T cell number J:128515
thymus hypoplasia J:128515
Bcl11btm1Jpk/Bcl11btm1Jpk
(involves: BALB/c * C57BL/6 * CBA)
abnormal T cell differentiation J:83651
abnormal T cell morphology J:83651
abnormal T cell receptor beta chain V(D)J recombination J:83651
abnormal thymus cortex morphology J:83651
abnormal thymus medulla morphology J:83651
absent thymus corticomedullary boundary J:83651
decreased double-positive T cell number J:83651
increased CD8-positive, alpha-beta T cell number J:83651
increased double-negative T cell number J:83651
increased thymocyte apoptosis J:83651
thymus hypoplasia J:83651
Bcl11btm1Peli/Bcl11btm1Peli
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6J)
abnormal NK cell differentiation J:161373
Bcl11btm2.1Jpk/Bcl11b+
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * C57BL/6J * DBA/2)
immune system phenotype J:210122
Bcl11btm2.1Jpk/Bcl11b+
Tg(Lck-cre)1Jtak/0

(involves: C57BL/6)
abnormal T cell number J:210122
decreased CD4-positive, alpha-beta T cell number J:210122
decreased CD8-positive, alpha-beta T cell number J:210122
decreased double-positive T cell number J:210122
decreased thymocyte number J:210122
increased double-negative T cell number J:210122
Bclaf1tm1Raz/Bclaf1+
(involves: 129P2/OlaHsd * C57BL/6)
decreased T cell proliferation J:158087
Bclaf1tm1Raz/Bclaf1tm1Raz
(involves: 129P2/OlaHsd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:158087
decreased T cell proliferation J:158087
increased B cell number J:158087
Bcmd2CAST/EiJ/Bcmd2CAST/EiJ
(AW.CAST-Bcmd2)
increased mast cell number J:75340
Bco2tm1Dnp/Bco2tm1Dnp
(involves: 129S6/SvEvTac * C57BL/6)
enlarged spleen J:166153
increased spleen weight J:166153
Bcortm1.1Vjba/Y
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S1/Sv * C57BL/6 * CBA/Ca)
increased neutrophil cell number J:231455
Bcrtm1(BCR/ABL)Tsr/Bcr+
Runx1tm3Dow/Runx1+
Tg(Vav1-cre)#Cgp/0

(involves: C57BL/6)
decreased lymphocyte cell number J:203111
increased monocyte cell number J:203111
increased neutrophil cell number J:203111
Bcrtm1Hkp/Bcrtm1Hkp
(involves: 129S2/SvPas)
abnormal neutrophil physiology J:23804
increased leukocyte cell number J:23804
increased neutrophil cell number J:23804
increased susceptibility to endotoxin shock J:23804
sepsis J:23804
Bcs1ltm1.1Levp/Bcs1ltm1.1Levp
(B6.129-Bcs1ltm1.1Levp)
abnormal macrophage morphology J:273501
increased macrophage cell number J:273501
increased neutrophil cell number J:273501
liver inflammation J:273501
Bdkrb1em1(IMPC)H/Bdkrb1em1(IMPC)H
(B6N;B6NTac-Bdkrb1em1(IMPC)H/H)
decreased neutrophil cell number J:211773
increased large unstained cell number J:211773
increased monocyte cell number J:211773
Bdkrb1tm1Bdr/Bdkrb1tm1Bdr
(involves: 129P2/OlaHsd)
abnormal acute inflammation J:63271
decreased susceptibility to endotoxin shock J:135789
Bdkrb1tm2Bdr/Bdkrb1tm2Bdr
Bdkrb2tm1Jfh/Bdkrb2tm1Jfh

(involves: 129S7/SvEvBrd * C57BL/6)
decreased susceptibility to endotoxin shock J:135789
Bdp1em1(IMPC)Tcp/Bdp1+
(C57BL/6NCrl-Bdp1em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Bean1em1(IMPC)H/Bean1em1(IMPC)H
(C57BL/6N-Bean1em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Becn1tm1.1Bflu/Becn1tm1.1Bflu
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:203090
decreased CD4-positive, alpha-beta T cell number J:203090
decreased CD8-positive, alpha-beta T cell number J:203090
decreased susceptibility to experimental autoimmune encephalomyelitis J:203090
decreased T cell proliferation J:203090
increased T cell apoptosis J:203090
Becn1tm1b(KOMP)Wtsi/Becn1+
(C57BL/6N-Becn1tm1b(KOMP)Wtsi/Ieg)
increased leukocyte cell number J:211773
Becn1tm1Blev/Becn1+
(involves: 129X1/SvJ * C57BL/6J)
abnormal immune system morphology J:86953
increased spleen germinal center number J:86953
increased spleen germinal center size J:86953
Becn1tm1Ebr/Becn1tm1Ebr
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
abnormal circulating chemokine level J:235399
abnormal macrophage physiology J:235399
abnormal spleen morphology J:235399
decreased circulating interleukin-10 level J:235399
glomerulonephritis J:235399
increased anti-double stranded DNA antibody level J:235399
increased anti-nuclear antigen antibody level J:235399
increased autoantibody level J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
increased circulating interleukin-12b level J:235399
increased IgG level J:235399
increased lymphocyte cell number J:235399
increased monocyte cell number J:235399
increased neutrophil cell number J:235399
increased susceptibility to systemic lupus erythematosus J:235399
Belr1BALB/cJ/Belr1BALB/cJ
(involves: BALB/cJ * C57BL/6J)
decreased susceptibility to parasitic infection J:133125
Belr1BALB/cJ/Belr1BALB/cJ
(B6.C-H2d/bByJ)
decreased susceptibility to parasitic infection J:133125
Berr1WLA/Pas/?
(involves: C57BL/6JRj * WLA/Pas)
decreased susceptibility to parasitic infection J:78027
Berr2WLA/Pas/?
(involves: C57BL/6JRj * WLA/Pas)
decreased susceptibility to parasitic infection J:78027
Best3tm1.1Zhoj/Best3tm1.1Zhoj
Tg(Tagln-cre)1Her/0

(involves: C57BL/6 * SJL)
aortitis J:338981
Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
(C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Bex6tm1.1(KOMP)Vlcg/Bex6tm1.1(KOMP)Vlcg
(B6N(Cg)-Bex6tm1.1(KOMP)Vlcg/J)
increased leukocyte cell number J:211773
Bglap/Bglap2tm1Kry/Bglap/Bglap2tm1Kry
(involves: 129S7/SvEvBrd * C57BL/6)
increased osteoclast cell number J:34440
Bglap/Bglap2tm1Kry/Bglap/Bglap2tm1Kry
(involves: 129S7/SvEvBrd * C57BL/6)
increased osteoclast cell number J:34440
Bgntm1Mfy/Y
(involves: 129S4/SvJae * C57BL/6)
osteoarthritis J:76203
Bgntm1Mfy/Y
Fmodtm1Aol/Fmodtm1Aol

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6)
osteoarthritis J:76203
Bgntm1Mfy/Y
Fmodtm1Aol/Fmodtm1Aol

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
accelerated temporomandibular joint osteoarthritis J:112779, J:117908
Bgntm1Mfy/Bgntm1Mfy
(involves: 129S4/SvJae)
osteoarthritis J:222369
Bgntm1Mfy/Bgntm1Mfy
Epyctm1Mhok/Epyctm1Mhok

(involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J)
osteoarthritis J:222369
Bgntm1Mfy/Bgntm1Mfy
Fmodtm1Aol/Fmodtm1Aol

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
accelerated temporomandibular joint osteoarthritis J:117908
bhe/bhe
(Not Specified)
chronic inflammation J:85113
Bhlhe40tm1Tan/Bhlhe40tm1Tan
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
abnormal CD4-positive T cell differentiation J:72651
abnormal CD4-positive, alpha-beta T cell physiology J:72651
abnormal immune system cell morphology J:72651
abnormal immune system physiology J:72651
abnormal lymph node germinal center morphology J:72651
abnormal susceptibility to autoimmune disorder J:72651
abnormal T cell activation J:72651
decreased double-positive T cell number J:72651
decreased interleukin-2 secretion J:72651
decreased T cell proliferation J:72651
increased anti-nuclear antigen antibody level J:72651
increased CD4-positive, alpha-beta T cell number J:72651
increased CD8-positive, alpha-beta T cell number J:72651
increased double-negative T cell number J:72651
increased IgE level J:72651
increased IgG1 level J:72651
increased spleen germinal center number J:72651
increased spleen white pulp amount J:72651
lymph node hyperplasia J:72651
spleen hyperplasia J:72651
thymus hyperplasia J:72651
Bhlhe41tm1.1Cdon/Bhlhe41tm1.1Cdon
(B6.129S6-Bhlhe41tm1.1Cdon)
abnormal lymphocyte cell number J:157740
abnormal T-helper 2 cell differentiation J:157740
decreased eosinophil cell number J:157740
decreased interferon-gamma secretion J:157740
decreased interleukin-2 secretion J:157740
decreased interleukin-5 secretion J:157740
decreased interleukin-13 secretion J:157740
decreased macrophage cell number J:157740
decreased neutrophil cell number J:157740
decreased T cell proliferation J:157740
increased interleukin-4 secretion J:157740
increased interleukin-17 secretion J:157740
Bhmttm1b(EUCOMM)Hmgu/Bhmttm1b(EUCOMM)Hmgu
(C57BL/6N-Bhmttm1b(EUCOMM)Hmgu/Bay)
increased spleen weight J:211773
Bicdl1tm2b(EUCOMM)Wtsi/Bicdl1tm2b(EUCOMM)Wtsi
(C57BL/6N-Bicdl1tm2b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Bicdl2em1(IMPC)Mbp/Bicdl2em1(IMPC)Mbp
(C57BL/6N-Bicdl2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Bidtm1Sjk/Bidtm1Sjk
(involves: 129X1/SvJ * C57BL/6)
decreased susceptibility to endotoxin shock J:117693
Bin1tm1Gcp/Bin1tm1Gcp
(involves: 129S6/SvEvTac * C57BL/6J)
immune system phenotype J:83753
Bin1tm1Gcp/Bin1tm2Gcp
Tg(Wap-cre)11738Mam/0

(involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL)
endometrium inflammation J:117330
Bin3tm1Gcp/Bin3tm1Gcp
(involves: 129 * C57BL/6)
enlarged spleen J:133313
liver inflammation J:133313
lung inflammation J:133313
Birc2tm1Jda/Birc2tm1Jda
(B6.129P2-Birc2tm1Jda)
decreased lymphocyte cell number J:97656
Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1.1Rbr/Birc3tm1.1Rbr

(involves: C57BL/6 * NZB)
immune system phenotype J:172843
Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1.1Rbr/Birc3tm1.1Rbr
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * NZB)
decreased B cell apoptosis J:172843
decreased germinal center B cell number J:172843
decreased spleen germinal center size J:172843
enlarged lymph nodes J:172843
enlarged spleen J:172843
increased B cell number J:172843
increased follicular B cell number J:172843
increased marginal zone B cell number J:172843
Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1.1Rbr/Birc3tm1.1Rbr
Cd19tm1(cre)Cgn/Cd19+
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass

(involves: 129P2/OlaHsd * C57BL/6 * NZB)
immune system phenotype J:172843
Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * NZB)
immune system phenotype J:172843
Birc2tm2.1Jda/Birc2tm2.1Jda
(B6.Cg-Birc2tm2.1Jda)
immune system phenotype J:199221
increased interferon-gamma secretion J:199221
increased T cell proliferation J:199221
Birc3tm1Jda/Birc3tm1Jda
(B6.Cg-Birc3tm1Jda)
abnormal gut-associated lymphoid tissue morphology J:166899
abnormal lymphocyte cell number J:166899
decreased B cell apoptosis J:166899
decreased follicular B cell number J:166899
decreased IgG1 level J:166899
decreased immature B cell number J:166899
enlarged mesenteric lymph nodes J:166899
increased B cell number J:166899
increased B cell proliferation J:166899
increased IgA level J:166899
increased IgG3 level J:166899
increased IgM level J:166899
increased marginal zone B cell number J:166899
increased T cell number J:166899
lymph node hyperplasia J:166899
Birc3tm1Jda/Birc3tm1Jda
(involves: 129 * C57BL/6)
increased interferon-gamma secretion J:199221
increased T cell proliferation J:199221
Birc3tm1Rgk/Birc3tm1Rgk
(B6.129X1-Birc3tm1Rgk)
abnormal cytokine secretion J:144012
abnormal immune cell physiology J:144012
abnormal interleukin-1 beta secretion J:144012
abnormal interleukin-12 secretion J:144012
abnormal leukocyte cell number J:144012
abnormal macrophage physiology J:144012
abnormal T cell physiology J:144012
abnormal tumor necrosis factor secretion J:144012
decreased macrophage cell number J:144012
decreased susceptibility to endotoxin shock J:144012
Birc5tm1Mak/Birc5tm1Mak
Tg(Lck-cre)I57Jxm/0

(involves: 129P2/OlaHsd)
abnormal T cell morphology J:90892
abnormal thymus corticomedullary boundary morphology J:90892
decreased double-negative T cell number J:90892
decreased thymocyte number J:90892
increased T cell apoptosis J:90892
small thymus J:90892
Birc5tm1Wnt/Birc5tm1Emc
Tg(Cd4-cre)1Cwi/0

(involves: 129S/SvEv * C57BL/6 * DBA/2)
abnormal T cell differentiation J:87435
Birc5tm1Wnt/Birc5tm1Emc
Tg(Lck-cre)1Cwi/0

(involves: 129S/SvEv * C57BL/6 * DBA/2)
decreased double-positive T cell number J:87435
decreased T cell number J:87435
increased double-negative T cell number J:87435
small lymph nodes J:87435
thymus hypoplasia J:87435
Birc6tm1Nai/Birc6tm1Nai
(involves: 129S4/SvJae * C57BL/6J)
increased thymocyte apoptosis J:96768
Bld/Bld+
(involves: BALB/cCi)
increased incidence of corneal inflammation J:5076
Blkm1Btlr/Blkm1Btlr
(C57BL/6J-Blkm1Btlr)
increased IgE level J:255004
increased interleukin-1 beta secretion J:255004
Blktm1Tara/Blktm1Tara
Fyntm1Sor/Fyntm1Sor
Lyntm1Ard/Lyntm1Ard

(either: B6.129-Lyntm1Ard Fyntm1Sor Blktm1Tara or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6))
abnormal B cell differentiation J:115080
abnormal pro-B cell differentiation J:115080
arrested B cell differentiation J:115080
decreased B cell number J:115080
decreased immature B cell number J:115080
decreased pre-B cell number J:115080
Blmtm3Brd/Blmtm3Brd
(involves: 129S7/SvEvBrd * C57BL/6)
decreased IgM level J:66261
Blmtm4Ches/Blmtm4Ches
Cd19tm1(cre)Cgn/Cd19+
Nsmce2tm2.1Ofc/Nsmce2tm2.1Ofc

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL)
abnormal B cell morphology J:227197
abnormal B cell physiology J:227197
decreased B cell number J:227197
small spleen J:227197
Blmtm4Ches/Blmtm4Ches
Trp53bp1tm1Jc/Trp53bp1tm1Jc
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
abnormal class switch recombination J:194603
Blmhtm1Geh/Blmhtm1Geh
(either: (involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J))
dermatitis J:54585
Blnkem1(IMPC)H/Blnkem1(IMPC)H
(C57BL/6N-Blnkem1(IMPC)H/H)
decreased basophil cell number J:211773
decreased large unstained cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased spleen weight J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
small spleen J:211773
Blnkm1Btlr/Blnkm1Btlr
(C57BL/6J-Blnkm1Btlr)
arrested B cell differentiation J:159439
decreased IgG level J:159439
decreased IgM level J:159439
decreased mature B cell number J:159439
increased CD4-positive, alpha-beta T cell number J:159439
increased CD8-positive, alpha-beta T cell number J:159439
Blnkm1Btlr/Blnkm1Btlr
(involves: C57BL/6J)
arrested B cell differentiation J:185495
decreased IgM level J:185495
immune system phenotype J:185495
Blnktm1Achn/Blnk+
(involves: 129S4/SvJae * 129X1/SvJ * BALB/c * C3H * C57BL/6)
decreased B cell proliferation J:82430
Blnktm1Achn/Blnk+
Btktm1Wk/Btktm1Wk
Tg(IGH-Btk)1Witt/0

(involves: 129S4/SvJae * 129X1/SvJ * BALB/c * C3H * C57BL/6)
abnormal B cell physiology J:82430
decreased B cell proliferation J:82430
Blnktm1Achn/Blnktm1Achn
(involves: 129X1/SvJ)
abnormal B cell differentiation J:58805
abnormal mature B cell morphology J:58805
absent B-1b cells J:58805
arrested B cell differentiation J:58805
decreased B-1a cell number J:58805
decreased immunoglobulin level J:58805
decreased mature B cell number J:58805
decreased splenocyte number J:58805
increased pro-B cell number J:58805
Blnktm1Dkit/Blnktm1Dkit
(involves: C57BL/6)
abnormal B cell apoptosis J:143854
abnormal B cell differentiation J:84040
abnormal immature B cell morphology J:94297
abnormal plasma cell differentiation J:143854
abnormal pre-B cell morphology J:84040
arrested B cell differentiation J:143854
decreased follicular B cell number J:143854
decreased IgG3 level J:143854
decreased IgM level J:143854
decreased immature B cell number J:84040
decreased marginal zone B cell number J:143854
decreased mature B cell number J:84040
decreased transitional stage B cell number J:143854
increased anti-double stranded DNA antibody level J:94297
increased B cell apoptosis J:143854
Blnktm1Dkit/Blnktm1Dkit
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn

(involves: 129P2/OlaHsd * C57BL/6 * NZB)
abnormal pre-B cell morphology J:84040
absent immature B cells J:84040
absent mature B cells J:84040
arrested B cell differentiation J:84040
decreased pre-B cell number J:84040
enlarged lymph nodes J:84040
enlarged spleen J:84040
Blnktm1Dkit/Blnktm1Dkit
Igh-Jtm1(3H9-VDJ)Mwg/Igh-J+

(involves: C57BL/6 * NZB)
abnormal immature B cell morphology J:94297
Blnktm1Dkit/Blnktm1Dkit
Igh-Jtm1(3H9-VDJ)Mwg/Igh-J+
Igk-Jtm1Mwg/Igk-J+

(involves: C57BL/6 * NZB)
abnormal immature B cell morphology J:94297
Blnktm1Dkit/Blnktm1Dkit
Prkcdtm1Kin/Prkcdtm1Kin

(involves: 129P2/OlaHsd * C57BL/6 * NZB)
abnormal B cell proliferation J:143854
abnormal immunoglobulin level J:143854
abnormal plasma cell differentiation J:143854
arrested B cell differentiation J:143854
decreased B-1 B cell number J:143854
decreased B-2 B cell number J:143854
decreased follicular B cell number J:143854
decreased marginal zone B cell number J:143854
increased B cell apoptosis J:143854
increased IgA level J:143854
increased IgG1 level J:143854
increased IgG2b level J:143854
increased IgG3 level J:143854
increased IgM level J:143854
Blnktm1Kplm/Blnktm1Kplm
(involves: 129P2/OlaHsd)
abnormal B cell activation J:61130, J:131161
abnormal B cell differentiation J:61130, J:131161
absent B-1a cells J:61130
decreased B cell number J:61130, J:131161
decreased B cell proliferation J:61130
decreased immature B cell number J:61130
decreased mature B cell number J:61130
decreased pre-B cell number J:61130, J:120460
increased B cell apoptosis J:131161
increased pro-B cell number J:61130, J:131161
spleen hypoplasia J:131161
Blnktm1Kplm/Blnktm1Kplm
Ightm4Cgn/Igh+
Igktm1Rsky/Igk+

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:120460
decreased B cell number J:120460
increased pre-B cell number J:120460
increased transitional stage B cell number J:120460
Blnktm1Kplm/Blnktm1Kplm
Plcg2tm1.1Kuro/Plcg2+

(involves: 129P2/OlaHsd)
abnormal B cell activation J:131161
decreased B cell number J:131161
increased B cell apoptosis J:131161
Blnktm1Kplm/Blnktm1Kplm
Plcg2tm1.1Kuro/Plcg2tm1.1Kuro

(involves: 129P2/OlaHsd)
decreased B cell number J:131161
increased B cell apoptosis J:131161
spleen hypoplasia J:131161
Blnktm1Pjln/Blnktm1Pjln
(involves: BALB/c)
abnormal pre-B cell morphology J:58740
arrested B cell differentiation J:58740
decreased IgG3 level J:58740
decreased IgM level J:58740
decreased mature B cell number J:58740
enlarged spleen J:80332
increased mature B cell number J:157575
increased pre-B cell number J:58740, J:80332
Blnktm1Pjln/Blnktm1Pjln
Btktm1Gsv/Y

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal B cell differentiation J:94768
decreased IgG3 level J:94768
decreased IgM level J:94768
decreased immature B cell number J:94768
decreased immunoglobulin level J:94768
decreased mature B cell number J:94768
Blnktm1Pjln/Blnktm1Pjln
Btktm1Gsv/Y
Tg(CD19-BTK*K430R)XK24Rwhe/?

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * FVB)
abnormal B cell differentiation J:94768
decreased IgG3 level J:94768
decreased IgM level J:94768
decreased immunoglobulin level J:94768
Blnktm1Pjln/Blnktm1Pjln
Btktm1Wk/Btktm1Wk

(involves: 129S4/SvJae * BALB/c * C57BL/6)
arrested B cell differentiation J:70406
Bloc1s3rp/Bloc1s3rp
(involves: C57BL/10ScSn * C57BL/Tb)
abnormal NK cell physiology J:6801
Bloc1s5em1(IMPC)Tcp/Bloc1s5+
(C57BL/6NCrl-Bloc1s5em1(IMPC)Tcp/Tcp)
increased monocyte cell number J:211773
Bloc1s5mu-Btlr/Bloc1s5mu-Btlr
(C57BL/6J-Bloc1s5mu-Btlr)
immune system phenotype J:137494
Bloc1s6em1(IMPC)Mbp/Bloc1s6em1(IMPC)Mbp
(C57BL/6N-Bloc1s6em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged spleen J:211773
Bloc1s6pa/Bloc1s6pa
(B6.Cg-Bloc1s6pa/J)
abnormal NK cell physiology J:6801
lung inflammation J:4098
Bmal1em1Bwu/Bmal1em1Bwu
(C57BL/6-Bmal1em1Bwu)
abnormal macrophage physiology J:340220
Bmal1tm1Bra/Bmal1tm1Bra
(B6.129-Bmal1tm1Bra)
decreased basophil cell number J:191844
decreased leukocyte cell number J:110697
decreased lymphocyte cell number J:110697
decreased spleen weight J:110697
impaired leukocyte tethering or rolling J:191844
increased circulating fibrinogen level J:191844
increased eosinophil cell number J:191844
increased incidence of corneal inflammation J:110697
increased leukocyte cell number J:191844
increased lymphocyte cell number J:191844
increased monocyte cell number J:110697
increased neutrophil cell number J:110697, J:191844
Bmal1tm1Bra/Bmal1tm1Bra
(involves: 129/Sv * C57BL/6)
abnormal B cell differentiation J:118522
abnormal T cell subpopulation ratio J:118522
decreased B cell number J:135933, J:118522
decreased follicular B cell number J:118522
decreased IgG1 level J:118522
decreased lymphocyte cell number J:135933, J:118522
decreased transitional stage B cell number J:118522
increased neutrophil cell number J:135933
Bmftm1.1Ast/Bmftm1.1Ast
(B6.Cg-Bmftm1.1Anst)
abnormal B cell morphology J:133084
abnormal immune system cell morphology J:133084
abnormal spleen morphology J:133084
decreased B cell apoptosis J:133084
decreased T cell apoptosis J:133084
enlarged spleen J:133084
increased follicular B cell number J:133084
increased immature B cell number J:133084
increased immunoglobulin level J:133084
increased mature B cell number J:133084
increased pre-B cell number J:133084
increased transitional stage B cell number J:133084
spleen hyperplasia J:133084
Bmftm1Rjd/Bmftm1Rjd
(B6.129S6-Bmftm1Rjd)
decreased T cell apoptosis J:153652
enlarged spleen J:153652
increased B cell number J:153652
increased CD8-positive, alpha-beta T cell number J:153652
increased splenocyte number J:153652
Bmftm3.1Rjd/Bmftm3.1Rjd
(B6.129S6-Bmftm3.1Rjd)
decreased CD4-positive, alpha-beta T cell number J:153652
Bmgr2C57BL/6J/?
Prf1tm1Sdz/Prf1tm1Sdz

(involves: 129S6/SvEvTac * C57BL/6J)
abnormal response to transplant J:116666
Bmgr3129S6/SvEvTac/Bmgr3129S6/SvEvTac
Prf1tm1Sdz/Prf1tm1Sdz

(involves: 129S6/SvEvTac * C57BL/6J)
abnormal response to transplant J:116666
Bmgr4C57BL/6J/?
Ebmgr1129S6/SvEvTac/Ebmgr1129S6/SvEvTac
Prf1tm1Sdz/Prf1tm1Sdz

(involves: 129S6/SvEvTac * C57BL/6J)
abnormal response to transplant J:116666
Bmgr4C57BL/6J/?
Prf1tm1Sdz/Prf1tm1Sdz

(involves: 129S6/SvEvTac * C57BL/6J)
abnormal response to transplant J:116666
Bmi1tm1Brn/Bmi1tm1Brn
(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * FVB))
abnormal double-negative T cell morphology J:17712
abnormal spleen red pulp morphology J:17712
abnormal spleen white pulp morphology J:17712
abnormal thymus involution J:17712
decreased IgM level J:17712
decreased immature B cell number J:17712
decreased mature B cell number J:17712
decreased splenocyte proliferation J:17712
decreased thymocyte number J:17712
lung inflammation J:17712
small spleen J:17712
thymus cortex hypoplasia J:17712
Bmi1tm1Brn/Bmi1tm1Brn
(involves: 129P2/OlaHsd)
decreased double-positive T cell number J:134271
Bmi1tm1Brn/Bmi1tm1Brn
E2f6tm1Lees/E2f6tm1Lees

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
decreased double-positive T cell number J:134271
Bmi1tm1Sgon/Bmi1tm1Sgon
Commd10Tg(Vav1-icre)A2Kio/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/10 * CBA/Ca)
abnormal immune system cell morphology J:221849
abnormal immune system organ morphology J:221849
abnormal spleen morphology J:221849
abnormal spleen periarteriolar lymphoid sheath morphology J:221849
abnormal spleen white pulp morphology J:221849
abnormal thymus morphology J:221849
absent spleen germinal center J:221849
decreased B cell number J:221849
decreased spleen red pulp amount J:221849
decreased spleen white pulp amount J:221849
decreased T cell number J:221849
small spleen J:221849
small thymus J:221849
thymus atrophy J:221849
Bmi1tm1Sgon/Bmi1tm1Sgon
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/?

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
decreased lymphocyte cell number J:221849
decreased spleen weight J:221849
immune system phenotype J:221849
Bmp1tm1.1Dgr/Bmp1tm1.1Dgr
Tll1tm2.1Dgr/Tll1tm2.1Dgr
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * SJL)
increased osteoclast cell number J:210366
Bmp2tm1.1Mis/Bmp2tm1.2Mis
Tg(Col1a1-cre)1Bek/0

(involves: 129S4/SvJaeSor * 129S7/SvEvBrd * CD-1)
decreased osteoclast cell number J:210409
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0

(involves: 129S4/SvJaeSor * C57BL/6 * SJL)
abnormal bone marrow development J:118257
Bmp5se-Ca/Bmp5+
(SEACGn.CB-Bmp5se-Ca)
granulomatous inflammation J:5086
Bmp5se-Ca/Bmp5se-Ca
(CBA/Ca-Bmp5se-Ca)
granulomatous inflammation J:5086
Bmp5se-Ca/Bmp5se-Ca
(SEACGn.CB-Bmp5se-Ca)
granulomatous inflammation J:5086
Bmp5se/Bmp5se
(SEC/1Gn)
granulomatous inflammation J:5086
Bmp5se/Bmp5se
(SEAC/Gn)
granulomatous inflammation J:5086
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
Tg(Prrx1-cre)1Cjt/0

(involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * SJL/J)
joint inflammation J:221175
osteoarthritis J:221175
Bmp7tm1a(EUCOMM)Hmgu/Bmp7+
(C57BL/6N-Bmp7tm1a(EUCOMM)Hmgu/H)
increased monocyte cell number J:165965
Bmp7tm1Rob/Bmp7+
Bmp8atm1Blh/Bmp8atm1Blh

(involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6)
granulomatous inflammation J:78867
Bmp8atm1Blh/Bmp8a+
Bmp8btm1Blh/Bmp8b+

(involves: 129/Sv * 129S6/SvEvTac * Black Swiss)
granulomatous inflammation J:46927
Bmp8atm1Blh/Bmp8atm1Blh
(involves: 129S6/SvEvTac * Black Swiss)
granulomatous inflammation J:46927
Bmp10b2b2711Clo/Bmp10b2b2711Clo
(C57BL/6J-Bmp10b2b2711Clo)
thymus hypoplasia J:175213
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129S7/SvEvBrd * C57BL/6 * CBA)
stomach inflammation J:163367
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Tg(Col1a1-cre/Esr1*)1Mis/0

(involves: 129S7/SvEvBrd)
abnormal osteoclast differentiation J:143588
abnormal osteoclast physiology J:143588
decreased osteoclast cell number J:143588
Bmpr1atm2.1Bhr/Bmpr1atm2.2Bhr
Tg(Gdf5-cre,-ALPP)1Kng/0

(involves: 129 * C57BL/6 * FVB/N-Tg(Gdf5-cre-ALPP)1Kng)
osteoarthritis J:97780
Bmpr2tm1Kmi/Bmpr2+
(involves: 129S4/SvJae * C57BL/6J)
abnormal leukocyte physiology J:117167
Bmxtm1Ali/Bmxtm1Ali
(involves: 129S1/Sv * 129X1/SvJ)
decreased susceptibility to induced arthritis J:173099
Bnc1em1(IMPC)H/Bnc1em1(IMPC)H
(C57BL/6NTac-Bnc1em1(IMPC)H/H)
abnormal spleen morphology J:211773
increased leukocyte cell number J:211773
increased neutrophil cell number J:211773
Bnip1tm2b(KOMP)Wtsi/Bnip1+
(C57BL/6N-Bnip1tm2b(KOMP)Wtsi/Nju)
increased eosinophil cell number J:211773
Bnip3ltm1.1Gwd/Bnip3ltm1.1Gwd
(involves: 129 * C57BL/6)
abnormal spleen morphology J:141583
abnormal thrombopoiesis J:141583
enlarged spleen J:141583
increased spleen red pulp amount J:141583
Bnip3ltm1Ney/Bnip3ltm1Ney
(Not Specified)
enlarged spleen J:141545
spleen hyperplasia J:141545
Bnip5tm1.1(KOMP)Vlcg/Bnip5tm1.1(KOMP)Vlcg
(C57BL/6N-Bnip5tm1.1(KOMP)Vlcg/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Boctm1b(KOMP)Wtsi/Boctm1b(KOMP)Wtsi
(C57BL/6N-Boctm1b(KOMP)Wtsi/H)
increased basophil cell number J:211773
Bod1tm1b(KOMP)Wtsi/Bod1+
(C57BL/6N-Bod1tm1b(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Bod1lem1Bltn/Bod1lem1Bltn
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6J)
decreased IgG1 level J:337726
decreased IgG level J:337726
Bod1lem1Bltn/Bod1lem1Bltn
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6J * C57BL/6NTac)
abnormal class switch recombination J:337726
decreased IgG1 level J:337726
Boktm1.1Ast/Boktm1.1Ast
(involves: BALB/cJ * C57BL/6)
immune system phenotype J:203179
increased spleen weight J:203179
increased thymus weight J:203179
Boktm1b(EUCOMM)Hmgu/Boktm1b(EUCOMM)Hmgu
(C57BL/6N-Boktm1b(EUCOMM)Hmgu/Tcp)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Bomb1NSF/N/Bomb1NSF/N
(involves: NFS/N * SL/Kh)
increased pre-B cell number J:55364
Bomb1SL/Kh/Bomb1SL/Kh
(involves: NFS/N * SL/Kh)
increased pre-B cell number J:55364
Bpgmm1Pgrs/Bpgmm1Pgrs
(involves: C57BL/6 * C57BL/10J)
decreased susceptibility to parasitic infection induced morbidity/mortality J:301620
enlarged spleen J:301620
immune system phenotype J:301620
Bpgmm1Pgrs/Bpgmm1Pgrs
(involves: A/J)
decreased susceptibility to parasitic infection induced morbidity/mortality J:301620
Bpitm1.1Buls/Bpitm1.1Buls
(involves: BALB/cJ * C57BL/6J)
abnormal circulating interleukin level J:346703
abnormal immune cell physiology J:346703
abnormal interleukin secretion J:346703
decreased circulating interferon-gamma level J:346703
enlarged mesenteric lymph nodes J:346703
immune system phenotype J:346703
increased susceptibility to induced colitis J:346703
increased T cell number J:346703
Bpifa1m1Ingm/Bpifa1m1Ingm
(involves: C3HeB/FeJ)
increased interleukin-1 alpha secretion J:195535
increased interleukin-1 beta secretion J:195535
increased susceptibility to bacterial infection J:195535
increased susceptibility to otitis media J:221346
increased tumor necrosis factor secretion J:195535
lung inflammation J:195535
Bpifa1tm1(KOMP)Vlcg/Bpifa1tm1(KOMP)Vlcg
(involves: C57BL/6J * C57BL/6NTac)
increased susceptibility to bacterial infection J:171589
Bpifa1tm1.1Jpst/Bpifa1tm1.1Jpst
Scgb1a1tm1(cre/ERT)Blh/Scgb1a1tm1(cre/ERT)Blh

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL)
increased susceptibility to Orthomyxoviridae infection J:265391
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:265391
Bpifa1tm1.2Jpst/Bpifa1tm1.2Jpst
(involves: BALB/cJ * C57BL/6 * C57BL/6J * SJL)
increased susceptibility to Orthomyxoviridae infection J:265391
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:265391
Bptfem1Zfa/Bptfem1Zfa
Tg(Rorc-cre)1Litt/0

(involves: C57BL/6 * FVB)
increased susceptibility to bacterial infection J:259392
increased susceptibility to bacterial infection induced morbidity/mortality J:259392
Bptftm1.1Cwu/Bptftm1.1Cwu
Emx1tm1(cre)Krj/Emx1+

(involves: 129S1/Sv * 129S2/SvPas * C57BL/6)
microgliosis J:334252
Braftm1(ARAF)Urr/Braftm1(ARAF)Urr
(involves: 129S1/Sv * C57BL/6 * CD-1)
decreased spleen weight J:112971
decreased thymus weight J:112971
Braftm1Bbd/Braf+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal immune system physiology J:170095
abnormal thymus morphology J:170095
decreased thymocyte number J:170095
increased splenocyte apoptosis J:170095
increased thymocyte apoptosis J:170095
thymus atrophy J:170095
Braftm1Bbd/Braf+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1)
abnormal immune system physiology J:170095
abnormal thymus morphology J:170095
decreased thymocyte number J:170095
increased splenocyte apoptosis J:170095
increased thymocyte apoptosis J:170095
thymus atrophy J:170095
Braftm1Bbd/Braf+
(B6.129-Braftm1Bbd)
abnormal immune system physiology J:170095
abnormal thymus morphology J:170095
decreased thymocyte number J:170095
increased splenocyte apoptosis J:170095
increased thymocyte apoptosis J:170095
thymus atrophy J:170095
Braftm1Cpri/Braf+
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased leukocyte cell number J:104375
enlarged spleen J:104375
Braftm1Mmcm/Braftm1Mmcm
Cd207tm2.1(cre)Bjec/Cd207+

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
increased dendritic cell number J:211690
liver inflammation J:211690
lung inflammation J:211690
Braftm1Mmcm/Braftm1Mmcm
Tg(Itgax-cre)1-1Reiz/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
cytokine storm J:211690
enlarged lymph nodes J:211690
granulomatous inflammation J:211690
hepatosplenomegaly J:211690
increased dendritic cell number J:211690
increased inflammatory response J:211690
Braftm1Tumg/Braf+
Tg(CAG-cre)2Osb/0

(involves: C57BL * C57BL/6J * DBA)
abnormal lymph organ development J:216228
Braftm1Wds/Braftm1Wds
Raf1tm2Bacc/Raf1tm2Bacc
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129P2/OlaHsd * C57BL/6J * CBA/J)
small thymus J:144862
Braftm2Cpri/Braf+
Tg(CMV-cre)1Cgn/0

(B6.Cg-Braftm2Cpri Tg(CMV-cre)1Cgn)
enlarged spleen J:187371
increased spleen weight J:187371
lymphoid hyperplasia J:187371
Brapem1(IMPC)Mbp/Brap+
(C57BL/6NCrl-Brapem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Brca1tm2.1Cxd/Brca1tm2.1Cxd
Shld1em1Nus/Shld1em1Nus

(involves: 129S6/SvEvTac * C57BL/6NCrl)
abnormal class switch recombination J:307190
Brca1tm2.1Cxd/Brca1tm2.1Cxd
Trp53tm1Brd/Trp53+

(involves: 129S6/SvEvTac * 129S7/SvEvBrd)
enlarged thymus J:81541
Brca1tm2.1Cxd/Brca1tm2.1Cxd
Trp53bp1tm1Jc/Trp53bp1tm1Jc

(involves: 129 * 129S6/SvEvTac)
abnormal class switch recombination J:307190
Brca1tm2Mak/Brca1tm2Mak
Cdkn1atm1Tyj/Cdkn1atm1Tyj
Tg(Lck-cre)548Jxm/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased thymocyte number J:63282
immune system phenotype J:63282
Brca1tm2Mak/Brca1tm2Mak
Chek2tm1Mak/Chek2tm1Mak
Tg(Lck-cre)548Jxm/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:90512
Brca1tm2Mak/Brca1tm2Mak
Tg(BCL2)36Wehi/?
Tg(Lck-cre)548Jxm/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:63282
Brca1tm2Mak/Brca1tm2Mak
Tg(Lck-cre)548Jxm/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal immune system organ morphology J:63282
abnormal T cell number J:63282
decreased double-positive T cell number J:63282
decreased single-positive T cell number J:63282
decreased T cell proliferation J:63282
decreased thymocyte number J:63282
increased double-negative T cell number J:63282
Brca1tm2Mak/Brca1tm2Mak
Tg(Lck-cre)548Jxm/?
Tg(TcrLCMV)327Sdz/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal T cell number J:63282
decreased double-positive T cell number J:63282
decreased T cell proliferation J:63282
decreased thymocyte number J:63282
increased double-negative T cell number J:63282
Brca1tm2Mak/Brca1tm2Mak
Tg(Lck-cre)548Jxm/?
Trp53tm1Brd/Trp53tm1Brd

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:63282
Brca1tm5.1Cxd/Brca1tm5.1Cxd
(involves: 129S6/SvEvTac * FVB/N)
dermatitis J:155810
Brca2tm1Cam/Brca2tm1Cam
(involves: 129S/SvEv * MF1)
increased thymus weight J:46812
Brca2tm1Hst/Brca2tm1Hst
(involves: 129S7/SvEvBrd * C57BL/6)
sepsis J:82434
Brca2tm1Kamc/Brca2tm1Kamc
(involves: 129P2/OlaHsd * BALB/c)
spleen hypoplasia J:144998
Brca2tm1Mak/Brca2tm2Mak
Tg(Lck-cre)548Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:79697
increased T cell apoptosis J:79697
Brca2tm1Mak/Brca2tm2Mak
Trp53tm1Brd/Trp53tm1Brd
Tg(Lck-cre)548Jxm/0

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA)
immune system phenotype J:79697
increased activated T cell number J:79697
Brd2em1(IMPC)Wtsi/Brd2+
(C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg)
decreased CD8-positive, alpha-beta T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
Brd2em1(IMPC)Wtsi/Brd2em1(IMPC)Wtsi
(C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg)
abnormal thymus topology J:239583
absent connection between subcutaneous lymph vessels and lymph sac J:239583
blood in lymph vessels J:239583
small thymus J:239583
Brd2Gt(RRT234)Byg/Brd2+
(B6.129P2-Brd2Gt(RRT234)Byg)
increased circulating interleukin-1 beta level J:159964
increased circulating tumor necrosis factor level J:159964
Brd9em1(IMPC)Tcp/Brd9+
(C57BL/6NCrl-Brd9em1(IMPC)Tcp/Tcp)
increased neutrophil cell number J:211773
Brf1tm1Arte/Brf1tm1Arte
Tg(Cyp1a1-cre)1Dwi/0

(involves: C57BL/6 * CBA)
liver inflammation J:285667
Brix1tm1b(KOMP)Mbp/Brix1+
(C57BL/6N-Brix1tm1b(KOMP)Mbp/Mhzh)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Brpf1tm1a(EUCOMM)Wtsi/Brpf1+
(Not Specified)
decreased T cell number J:165965
increased monocyte cell number J:165965
Brwd1em1(IMPC)Tcp/Brwd1em1(IMPC)Tcp
(C57BL/6NCrl-Brwd1em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Bscl2tm1.1Lchan/Bscl2tm1.1Lchan
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
enlarged spleen J:183701
Bscl2tm1.2Gliu/Bscl2tm1.2Gliu
(involves: 129 * 129S4/SvJaeSor * C57BL/6 * FVB/N)
enlarged spleen J:173404
Bscl2tm1b(EUCOMM)Hmgu/Bscl2tm1b(EUCOMM)Hmgu
(C57BL/6N-Bscl2tm1b(EUCOMM)Hmgu/Ics)
increased large unstained cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Bsgtm1.1Znc/Bsgtm1.1Znc
Tg(Lck-cre)19Hhan/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA)
abnormal T cell activation J:207886
decreased double-positive T cell number J:207886
decreased single-positive T cell number J:207886
decreased thymocyte number J:207886
decreased thymus weight J:207886
immune system phenotype J:207886
increased T cell proliferation J:207886
Bsgtm1Tmu/Bsgtm1Tmu
(involves: 129S2/SvPas * C57BL/6J)
interstitial pneumonia J:46376
Bsgtm1Tmu/Bsgtm1Tmu
(involves: 129/Sv * 129S2/SvPas)
interstitial pneumonia J:46376
Bsgtm1Tmu/Bsgtm1Tmu
(involves: 129S2/SvPas)
decreased circulating complement protein level J:287636
glomerulonephritis J:287636
increased spleen weight J:287636
increased splenocyte number J:287636
increased susceptibility to systemic lupus erythematosus J:287636
increased T-helper 17 cell number J:287636
Bsp/Bsp
(C57BL/6By)
abnormal spleen morphology J:6856
Bsp/Bsp+
(C57BL/6By)
abnormal spleen morphology J:6856
Bst1tm1Thir/Bst1tm1Thir
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:111424
abnormal humoral immune response J:111424
decreased B-1 B cell number J:111424
decreased IgA level J:111424
decreased IgG3 level J:111424
decreased immature B cell number J:111424
immune system phenotype J:111424
increased B cell number J:111424
Bst2tm1.1Bsz/Bst2tm1.1Bsz
(involves: C57BL/6)
enlarged lymph nodes J:180252
enlarged spleen J:180252
increased susceptibility to Retroviridae infection J:180252
Btbd2em1(IMPC)Mbp/Btbd2em1(IMPC)Mbp
(C57BL/6N-Btbd2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Btbd3tm1b(EUCOMM)Hmgu/Btbd3tm1b(EUCOMM)Hmgu
(C57BL/6N-Btbd3tm1b(EUCOMM)Hmgu/Ccpcz)
increased CD8-positive, CD25-positive alpha-beta T cell number J:211773
Btbd7em1(IMPC)Ccpcz/Btbd7em1(IMPC)Ccpcz
(C57BL/6NCrl-Btbd7em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Btbd16tm2b(EUCOMM)Hmgu/Btbd16tm2b(EUCOMM)Hmgu
(C57BL/6N-Btbd16tm2b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Btbd17em1(IMPC)Mbp/Btbd17em1(IMPC)Mbp
(C57BL/6NCrl-Btbd17em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
Btbd18em1(IMPC)Ccpcz/Btbd18em1(IMPC)Ccpcz
(C57BL/6NCrl-Btbd18em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Btcem1(IMPC)Mbp/Btcem1(IMPC)Mbp
(C57BL/6N-Btcem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
increased neutrophil cell number J:211773
Btf3em1(IMPC)Tcp/Btf3+
(C57BL/6NCrl-Btf3em1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
Btg1em1(IMPC)Mbp/Btg1em1(IMPC)Mbp
(C57BL/6NCrl-Btg1em1(IMPC)Mbp/Mmucd)
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Btkm1Anu/Btkm1Anu
(involves: BXSB/MpJ * C57BL/6JAnu * SB/Le)
decreased B cell number J:104190
Btkm1Anu/Btkm1Anu
X/Yaa

(involves: BXSB/MpJ * C57BL/6JAnu * SB/Le)
decreased B cell number J:104190
Btkm2Anu/Btkm2Anu
(C57BL/6NCrlAnu-Btkm2Anu)
increased IgM level J:104190
increased immature B cell number J:104190
Btktm1a(EUCOMM)Hmgu/Y
(C57BL/6N-Btktm1a(EUCOMM)Hmgu/Ics)
increased CD4-positive, alpha-beta T cell number J:165965
Btktm1Gsv/Y
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:35769
abnormal B cell physiology J:94768
abnormal humoral immune response J:120989
abnormal immune system physiology J:35769
absent B-1a cells J:35769
absent mature B cells J:35769
decreased B cell number J:35769
decreased IgG3 level J:35769
decreased IgM level J:35769
decreased immature B cell number J:35769
decreased immunoglobulin level J:120989
Btktm1Gsv/Y
Tg(CD19-BTK*K430R)XK24Rwhe/?

(involves: 129P2/OlaHsd * C57BL/6 * FVB)
abnormal lymphocyte cell number J:120989
abnormal pre-B cell morphology J:120989
absent B-1a cells J:120989
decreased B cell apoptosis J:120989
decreased B cell number J:120989
decreased immunoglobulin level J:120989
immune system phenotype J:94768
Btktm1Gsv/Btk+
(involves: 129P2/OlaHsd * C57BL/6)
absent B-1a cells J:35769
decreased B cell number J:35769
decreased mature B cell number J:35769
Btktm1Witt/Btktm1Wk
(involves: 129S4/SvJae * 129X1/SvJ)
immune system phenotype J:104167
Btktm1Wk/Btktm1Wk
(involves: 129S4/SvJae * C57BL/6)
abnormal B cell activation J:28968
abnormal B cell differentiation J:28968
abnormal lymph node germinal center morphology J:82298
decreased B cell proliferation J:82298
decreased IgG3 level J:28968, J:82298
decreased IgM level J:28968, J:82298
decreased mature B cell number J:28968, J:82298
decreased spleen germinal center number J:82298
decreased spleen germinal center size J:82298
increased pro-B cell number J:28968
Btktm1Wk/Btktm1Wk
Cd40tm1Geha/Cd40tm1Geha

(involves: 129S4/SvJae * C57BL/6)
abnormal humoral immune response J:82298
absent lymph node germinal center J:82298
absent spleen germinal center J:82298
decreased B cell number J:82298
decreased B cell proliferation J:82298
decreased IgA level J:82298
decreased IgG2a level J:82298
decreased IgG2b level J:82298
decreased IgG3 level J:82298
decreased IgM level J:82298
decreased mature B cell number J:82298
Btktm1Wk/Btktm1Wk
Tectm1Welm/Tectm1Welm

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:66080
abnormal humoral immune response J:66080
abnormal spleen marginal zone morphology J:66080
abnormal spleen morphology J:66080
abnormal spleen white pulp morphology J:66080
decreased B cell number J:66080
decreased B cell proliferation J:66080
decreased IgG2a level J:66080
decreased IgG3 level J:66080
decreased IgM level J:66080
decreased immunoglobulin level J:66080
increased pre-B cell number J:66080
Btktm1Wk/Btktm1Wk
Tg(IGH-Btk)1Witt/0

(involves: 129S4/SvJae * 129X1/SvJ * BALB/c * C3H * C57BL/6)
decreased B cell proliferation J:82430
Btkvila/Btkvila
(C57BL/6JAnu-Btkvila/AnuApb)
abnormal leukocyte morphology J:104190
decreased B cell number J:104190
decreased IgD level J:104190
increased IgE level J:104190
increased IgG level J:104190
Btkxid/Y
(CBA/HN-Btkxid)
decreased B cell number J:81429
decreased B cell proliferation J:81429
decreased splenocyte number J:81429
Btkxid/Y
(involves: CBA/HN * DBA/2N)
decreased B cell number J:81429
decreased B cell proliferation J:81429
spleen hypoplasia J:81429
Btkxid/?
(involves: BALB/c * CBA/N)
decreased B cell proliferation J:108696
decreased B-1 B cell number J:108696
decreased IgG3 level J:108696
decreased IgM level J:108696
decreased mature B cell number J:108696
Btkxid/Y
Ikzf3tm1Kge/Ikzf3tm1Kge

(involves: 129S4/SvJae * CBA/CaHN)
decreased follicular B cell number J:69477
Btkxid/?
Ptpn6me/Ptpn6me

(involves: C57BL/6J * CBA/N * NFS)
increased autoantibody level J:30994
increased IgM level J:30994
increased splenocyte proliferation J:30994
Btkxid/?
Tg(IGH-Btk)1Witt/0

(involves: BALB/c * C3H * C57BL/6 * CBA/N)
decreased B cell proliferation J:108696
decreased B-1 B cell number J:108696
decreased IgG3 level J:108696
decreased IgM level J:108696
Btkxid/?
Tg(IGH-Btk)1Witt/Tg(IGH-Btk)1Witt

(involves: BALB/c * C3H * C57BL/6 * CBA/N)
decreased B cell proliferation J:108696
decreased B-1 B cell number J:108696
decreased IgG3 level J:108696
decreased IgM level J:108696
Btkxid/Btkxid
(CBA/CaHN-Btkxid/J)
abnormal macrophage physiology J:92639
abnormal neutrophil physiology J:92639
decreased acute inflammation J:92639
decreased follicular B cell number J:69477
decreased neutrophil cell number J:92639
decreased susceptibility to experimental autoimmune encephalomyelitis J:92639
impaired myelopoiesis J:92639
impaired neutrophil phagocytosis J:92639
increased susceptibility to bacterial infection induced morbidity/mortality J:128518
increased susceptibility to induced colitis J:92639
Btkxid/Btkxid
(involves: CBA/HN * DBA/2N)
abnormal B cell physiology J:81429
abnormal B cell proliferation J:81429
decreased B cell number J:81429
spleen hypoplasia J:81429
Btkxid/Btkxid
(CBA/HN-Btkxid)
abnormal lymphopoiesis J:7981
abnormal pre-B cell morphology J:7981
autoimmune response J:125114
decreased B cell number J:81429
decreased B cell proliferation J:81429
decreased splenocyte number J:81429
Btkxid/Btkxid
(involves: C57BL/6 * CBA)
immune system phenotype J:113083
Btkxid/Btkxid
(B6.CBA-Btkxid)
decreased transitional stage B cell number J:145687
Btkxid/Btkxid
Ikzf3tm1Kge/Ikzf3tm1Kge

(involves: 129S4/SvJae * CBA/CaHN)
decreased follicular B cell number J:69477
Btlatm1Dgra/Btlatm1Dgra
(involves: C57BL/6)
abnormal peripheral T cell anergy J:147751
abnormal T cell activation J:147751
Btlatm1Dgra/Btlatm1Dgra
Tg(TcraTcrb)425Cbn/?

(involves: C57BL/6)
abnormal peripheral T cell anergy J:147751
Btlatm1Dgra/Btlatm1Dgra
Tg(TcraTcrb)1100Mjb/?

(involves: C57BL/6)
abnormal peripheral T cell anergy J:147751
Btlatm1Kay/Btlatm1Kay
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal T cell activation J:89864
Btlatm1Kmm/Btlatm1Kmm
(involves: 129S/SvEv)
abnormal humoral immune response J:84084
increased B cell proliferation J:84084
increased IgG1 level J:84084
increased IgG2a level J:84084
increased IgG2b level J:84084
increased susceptibility to experimental autoimmune encephalomyelitis J:84084
increased T cell proliferation J:84084
Btlatm1Kmm/Btlatm1Kmm
(B6.129S-Btlatm1Kmm)
abnormal T cell activation J:119356
decreased interferon-gamma secretion J:119356
decreased interleukin-2 secretion J:119356
decreased T cell proliferation J:119356
increased length of allograft survival J:119356
increased T cell proliferation J:119356
Btlatm1Kmm/Btlatm1Kmm
Pdcd1tm1Hon/Pdcd1tm1Hon

(B6.129S-Pdcd1tm1Hon Btlatm1Kmm)
decreased length of allograft survival J:119356
increased T cell proliferation J:119356
Btlatm1Kmm/Btlatm1Kmm
Tg(DO11.10)10Dlo/?

(involves: 129S/SvEv * BALB/c * C3H * C57BL/6)
increased T cell proliferation J:84084
Btn2a2tm1.2Wrth/Btn2a2tm1.2Wrth
(C57BL/6-Btn2a2tm1.2Wrth)
abnormal T-helper 1 physiology J:232636
abnormal T-helper 2 physiology J:232636
increased anti-nuclear antigen antibody level J:232636
increased IgG1 level J:232636
increased IgG2c level J:232636
increased IgG level J:232636
increased response to antigen J:232636
increased susceptibility to experimental autoimmune encephalomyelitis J:232636
Btnl1em1Ahay/Btnl1em1Ahay
(Not Specified)
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:236526
decreased gamma-delta intraepithelial T cell number J:236526
Btnl1em2Ahay/Btnl1em2Ahay
Tg(Vil1-cre/ERT2)23Syr/0

(involves: C57BL/6 * DBA/2)
immune system phenotype J:291989
Btnl1em3Ahay/Btnl1em3Ahay
Btnl6em2Ahay/Btnl6em2Ahay
Tg(Vil1-cre/ERT2)23Syr/0

(involves: BALB/c * C57BL/6J * DBA/2)
immune system phenotype J:291989
Btnl1tm1(KOMP)Mbp/Btnl1tm1(KOMP)Mbp
(C57BL/6N-Btnl1tm1(KOMP)Mbp)
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:236526
decreased gamma-delta intraepithelial T cell number J:236526
Btnl1tm1(KOMP)Mbp/Btnl1tm1(KOMP)Mbp
Foxn1nu/Foxn1nu

(involves: albino stock * C57BL/6N)
decreased gamma-delta intraepithelial T cell number J:236526
Btnl1tm1(KOMP)Mbp/Btnl1tm1(KOMP)Mbp
Gt(ROSA)26Sortm1(rtTA*M2)Jae/0
Tg(tetO-Btnl1)#Ahay/0

(involves: 129S4/SvJae * C57BL/6 * C57BL/6N)
decreased gamma-delta intraepithelial T cell number J:236526
Btnl1tm1(KOMP)Mbp/Btnl1tm1(KOMP)Mbp
Tg(tetO-Btnl1)#Ahay/0
Tg(Vil-rtTA2*M2)1Rsmi/0

(involves: C57BL/6N * FVB/N)
decreased gamma-delta intraepithelial T cell number J:236526
Btnl2em1Wche/Btnl2em1Wche
(C57BL/6-Btnl2em1Wche)
abnormal cytokine level J:321348
abnormal gamma-delta T cell morphology J:321348
large intestinal inflammation J:321348
Btnl4em1(IMPC)Tcp/Btnl4em1(IMPC)Tcp
(C57BL/6NCrl-Btnl4em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Btnl4tm1(KOMP)Mbp/Btnl4tm1(KOMP)Mbp
(C57BL/6N-Btnl4tm1(KOMP)Mbp)
immune system phenotype J:291989
Btnl6em1.1Ahay/Btnl6em1.1Ahay
(Not Specified)
decreased CD4-positive, gamma-delta intraepithelial T cell number J:291989
Btnl6em1Ahay/Btnl6em1Ahay
Tg(Vil1-cre)20Syr/0

(involves: C57BL/6 * DBA/2)
decreased CD4-positive, gamma-delta intraepithelial T cell number J:291989
Btrctm1b(KOMP)Wtsi/Btrctm1b(KOMP)Wtsi
(C57BL/6N-Btrctm1b(KOMP)Wtsi/H)
increased monocyte cell number J:211773
Btrctm1Kin/Btrctm1Kin
(involves: C57BL/6)
abnormal lymphocyte morphology J:84639
Btrctm1Paga/Btrctm1Paga
Fbxw11tm1Ybn/Fbxw11tm1Ybn
Tg(Vil1-cre/ERT2)23Syr/?

(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2)
increased circulating interleukin-1 beta level J:206654
intestinal inflammation J:206654
Bub1tm1.1Tvd/Bub1tm1.1Tvd
(B6.129P2-Bub1tm1.1Tvd)
increased leukocyte cell number J:143035
Bub1bGt(neo-btk)1Dai/Bub1b+
(involves: 129S4/SvJae * C57BL/6)
enlarged spleen J:88223
Bub1btm1.1Hsl/Bub1b+
(involves: 129 * C57BL/6)
enlarged spleen J:201641
increased B cell proliferation J:201641
increased spleen white pulp amount J:201641
Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
(involves: BXSB/MpJ * C57BL/10ScSnOlaHsd)
autoimmune response J:145903
glomerulonephritis J:145903
increased autoantibody level J:145903
Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
(B10.BXSB-(D13Mit3-D13Mit78))
autoimmune response J:145049
increased anti-double stranded DNA antibody level J:145049
increased anti-single stranded DNA antibody level J:145049
increased autoantibody level J:145049
Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Gpab1C57BL/6J/?

(involves: BXSB/MpJ * C57BL/10ScSnOlaHsd)
autoimmune response J:145903
increased autoantibody level J:145903
Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
X/Yaa

(B10.BXSB-(D13Mit3-D13Mit78) Yaa)
autoimmune response J:145049
enlarged spleen J:145049
glomerulonephritis J:145049
increased anti-double stranded DNA antibody level J:145049
increased anti-single stranded DNA antibody level J:145049
increased autoantibody level J:145049
C1galt1ptl1/C1galt1ptl1
(C57BL/6-C1galt1ptl1)
abnormal thrombopoiesis J:115272
glomerulonephritis J:115272
kidney inflammation J:115272
C1galt1ptl1/C1galt1ptl1
Rag1tm1Bal/Rag1tm1Bal

(involves: 129S4/SvJae * C57BL/6)
kidney inflammation J:115272
C1qatm1Mjw/C1qatm1Mjw
(involves: 129P2/Ola * 129S/SvEv * C57BL/6)
glomerulonephritis J:47315
increased anti-histone antibody level J:47315
increased anti-nuclear antigen antibody level J:47315
increased susceptibility to bacterial infection J:83712
C1qatm1Mjw/C1qatm1Mjw
(involves: 129P2/Ola * 129S/SvEv)
immune system phenotype J:47315
C1qatm1Mjw/C1qatm1Mjw
Sle16129S6/SvEvTac/Sle16129S6/SvEvTac

(involves: 129S/SvEv * 129X1/Sv * C57BL/6)
increased anti-chromatin antibody level J:118645
increased anti-double stranded DNA antibody level J:118645
increased anti-nuclear antigen antibody level J:118645
increased anti-single stranded DNA antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle16129S6/SvEvTac/Sle16C57BL/6

(involves: 129S/SvEv * 129X1/Sv * C57BL/6)
increased anti-chromatin antibody level J:118645
increased anti-double stranded DNA antibody level J:118645
increased anti-nuclear antigen antibody level J:118645
increased anti-single stranded DNA antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle18C57BL/6/Sle18C57BL/6

(involves: 129S/SvEv * 129X1/Sv * C57BL/6)
increased anti-nuclear antigen antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle18C57BL/6/Sle18C57BL/6

(involves: 129P2/Ola * 129S/SvEv * C57BL/6)
increased anti-nuclear antigen antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle19C57BL/6/?

(involves: 129S/SvEv * 129X1/Sv * C57BL/6)
increased anti-nuclear antigen antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle19C57BL/6/?

(involves: 129P2/Ola * 129S/SvEv * C57BL/6)
increased anti-nuclear antigen antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle21129P2/Ola/?
Sle18C57BL/6/Sle18C57BL/6

(involves: 129P2/Ola * 129S/SvEv * C57BL/6)
increased anti-nuclear antigen antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle21129P2/Ola/Sle21129P2/Ola

(involves: 129P2/Ola * 129S/SvEv * C57BL/6)
increased anti-chromatin antibody level J:118645
increased anti-double stranded DNA antibody level J:118645
increased anti-nuclear antigen antibody level J:118645
increased anti-single stranded DNA antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle21129P2/Ola/Sle21C57BL/6

(involves: 129P2/Ola * 129S/SvEv * C57BL/6)
increased anti-chromatin antibody level J:118645
increased anti-double stranded DNA antibody level J:118645
increased anti-nuclear antigen antibody level J:118645
increased anti-single stranded DNA antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1ql2em1(IMPC)Mbp/C1ql2em1(IMPC)Mbp
(C57BL/6N-C1ql2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
C1ql3em1(IMPC)H/C1ql3em1(IMPC)H
(C57BL/6NTac-C1ql3em1(IMPC)H/H)
decreased eosinophil cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
C1ql4tm1Lex/C1ql4tm1Lex
(B6.129S5-C1ql4tm1Lex)
decreased leukocyte cell number J:344722
decreased lymphocyte cell number J:344722
C1qtnf1em1(IMPC)Mbp/C1qtnf1em1(IMPC)Mbp
(C57BL/6N-C1qtnf1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
C1qtnf3tm1Yiw/C1qtnf3tm1Yiw
(involves: C57BL/6NSlc)
immune system phenotype J:211893
increased IgG level J:211893
increased susceptibility to induced arthritis J:211893
joint inflammation J:211893
C1qtnf4em1Smoc/C1qtnf4em1Smoc
(C57BL/6J-C1qtnf4em1Smoc/Smoc)
abnormal macrophage differentiation J:302282
increased circulating interleukin-6 level J:302282
increased circulating interleukin-18 level J:302282
increased circulating tumor necrosis factor level J:302282
increased susceptibility to endotoxin shock J:302282
increased tumor necrosis factor secretion J:302282
C1qtnf6tm1Yiw/C1qtnf6tm1Yiw
(involves: 129P2/OlaHsd * C57BL/6J)
immune system phenotype J:227217
increased anti-nuclear antigen antibody level J:227217
increased autoantibody level J:227217
C1qtnf6tm1Yiw/C1qtnf6tm1Yiw
(B6.129P2-C1qtnf6tm1Yiw)
abnormal complement pathway J:227217
abnormal complement protein level J:227217
immune system phenotype J:227217
increased B cell number J:227217
increased circulating complement protein level J:227217
increased IgG level J:227217
increased susceptibility to experimental autoimmune encephalomyelitis J:227217
increased susceptibility to induced arthritis J:227217
increased susceptibility to type III hypersensitivity reaction J:227217
C1qtnf7tm1(KOMP)Vlcg/C1qtnf7tm1(KOMP)Vlcg
(C57BL/6N-C1qtnf7tm1(KOMP)Vlcg)
increased macrophage cell number J:244352
C2cd3em1(IMPC)Tcp/C2cd3+
(C57BL/6N-C2cd3em1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
C3tm1Crr/C3tm1Crr
(involves: 129S4/SvJae * C57BL/6)
abnormal cell-mediated immunity J:30152
abnormal humoral immune response J:64282
abnormal immune system morphology J:44240
abnormal immune system physiology J:44240
abnormal mast cell physiology J:44240
abnormal spleen germinal center morphology J:64282
abnormal tumor necrosis factor level J:44240
decreased circulating interleukin-6 level J:166640, J:152533
decreased circulating tumor necrosis factor level J:152533
decreased mast cell number J:44240
decreased neutrophil cell number J:44240
decreased osteoclast cell number J:166640
decreased spleen germinal center number J:64282
decreased spleen germinal center size J:64282
immune system phenotype J:64282
increased susceptibility to bacterial infection J:44240, J:30152
increased susceptibility to bacterial infection induced morbidity/mortality J:205353
liver inflammation J:30152
C3tm1Crr/C3tm1Crr
(B6.129S4-C3tm1Crr)
abnormal inflammatory response J:113463
abnormal neutrophil morphology J:113463
brain inflammation J:123658
decreased susceptibility to autoimmune hemolytic anemia J:145432
C3tm1Crr/C3tm1Crr
(B6;129S4-C3tm1Crr/J)
decreased susceptibility to Coronaviridae infection J:286325
increased susceptibility to bacterial infection J:136745
C3tm1Crr/C3tm1Crr
(involves: 129S4/SvJae)
glomerulonephritis J:44715
C3tm1Crr/C3tm1Crr
C4btm1Crr/C4btm1Crr
Faslpr/Faslpr

(involves: 129S4/SvJae * C57BL/6 * MRL)
abnormal immune system physiology J:127292
enlarged cervical lymph nodes J:127292
enlarged spleen J:127292
increased anti-double stranded DNA antibody level J:127292
increased anti-nuclear antigen antibody level J:127292
C3tm1Crr/C3tm1Crr
Cd59atm1Bpm/Cd59atm1Bpm

(B6.129-Cd59atm1Bpm C3tm1Crr)
increased T cell proliferation J:122201
C3tm1Crr/C3tm1Crr
Faslpr/Faslpr

(involves: 129S4/SvJae * C57BL/6 * MRL)
decreased susceptibility to autoimmune disorder J:127292
immune system phenotype J:127292
C3tm1Crr/C3tm1Crr
Fcer1gtm1Rav/Fcer1gtm1Rav
Tg(Ins2-TFRC/OVA)296Wehi/0

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
decreased susceptibility to autoimmune diabetes J:122114
C3tm1Crr/C3tm1Crr
Tg(Ins2-TFRC/OVA)296Wehi/0

(involves: 129S4/SvJae * C57BL/6)
decreased susceptibility to autoimmune diabetes J:122114
increased interferon-gamma secretion J:122114
increased T cell proliferation J:122114
insulitis J:122114
C3tm1Crr/C3tm1Crr
Zbtb20Tg(PDGFB-APPSwInd)20Lms/?

(involves: 129S4/SvJae * C57BL/6)
increased microglial cell activation J:135902
C3tm1Hrc/C3tm1Hrc
(either: (involves: 129S2/SvPas * C57BL/6) or (involves: 129X1/SvJ * C57BL/6))
increased susceptibility to bacterial infection J:56193
C3tm1Hrc/C3tm1Hrc
(B6.129-C3tm1Hrc)
impaired complement alternative pathway J:177350
C3tm1Hrc/C3tm1Hrc
Cr1ltm1Hmo/Cr1ltm1Hmo

(involves: 129/Sv * 129X1/SvJ * C57BL/6)
abnormal complement pathway J:76578
C3tm1Hrc/C3tm1Hrc
Lama2dy/Lama2dy

(either: (involves: 129S2/SvPas * 129P1/ReJ) or (involves: 129X1/SvJ * 129P1/ReJ))
decreased IgM level J:102959
increased IgG level J:102959
increased IgM level J:102959
C3tm1Hrc/C3tm1Hrc
Vsig4tm1Gne/Vsig4tm1Gne

(involves: 129/Sv * C57BL/6N)
immune system phenotype J:138691
C3tm1Pkna/C3tm1Pkna
(D1.129P2-C3tm1Pkna)
decreased susceptibility to induced arthritis J:88872
C3ar1tm1Cge/C3ar1tm1Cge
(involves: 129S4/SvJae * C57BL/6)
decreased circulating interleukin-6 level J:166640
decreased osteoclast cell number J:166640
C3ar1tm1Raw/C3ar1+
(involves: 129X1/SvJ * C57BL/6)
abnormal immune system physiology J:68807
C3ar1tm1Raw/C3ar1tm1Raw
(involves: 129X1/SvJ * C57BL/6)
increased circulating interleukin-1 beta level J:68807
increased susceptibility to endotoxin shock J:68807
C3ar1tm1Raw/C3ar1tm1Raw
(B6.129X1(B6)-C3ar1tm1Raw)
abnormal adaptive immunity J:80071
abnormal eosinophil physiology J:80071
abnormal interleukin level J:80071
abnormal T-helper 2 cell differentiation J:80071
abnormal T-helper 2 physiology J:80071
decreased eosinophil cell number J:80071
decreased IgE level J:80071
decreased IgG1 level J:80071
decreased interleukin-4 secretion J:80071
decreased lymphocyte cell number J:80071
decreased neutrophil cell number J:80071
decreased susceptibility to experimental autoimmune encephalomyelitis J:93791
impaired neutrophil recruitment J:80071
increased circulating interleukin-1 beta level J:93791
increased susceptibility to type I hypersensitivity reaction J:80071
C3ar1tm1Raw/C3ar1tm1Raw
Cpn1tm1Raw/Cpn1tm1Raw

(B6.129-C3ar1tm1Raw Cpn1tm1Raw)
increased acute inflammation J:148315
C4btm1Crr/C4btm1Crr
(involves: 129S4/SvJae * C57BL/6)
abnormal humoral immune response J:64282
abnormal spleen germinal center morphology J:64282
decreased spleen germinal center number J:64282
decreased spleen germinal center size J:64282
decreased susceptibility to bacterial infection J:30152
immune system phenotype J:64282, J:30152
increased susceptibility to bacterial infection induced morbidity/mortality J:30152
liver inflammation J:30152
C4btm1Crr/C4btm1Crr
(involves: 129S4/SvJae * C57BL/6J)
abnormal immune system physiology J:111811
glomerulonephritis J:111811
increased anti-double stranded DNA antibody level J:111811
increased anti-nuclear antigen antibody level J:111811
increased anti-single stranded DNA antibody level J:111811
increased macrophage cell number J:111811
increased neutrophil cell number J:111811
increased spleen germinal center number J:111811
increased spleen weight J:111811
C4btm1Crr/C4btm1Crr
(involves: 129S4/SvJae)
decreased susceptibility to Coronaviridae infection J:286325
glomerulonephritis J:44715
C4btm1Crr/C4btm1Crr
Faslpr/Faslpr

(involves: 129S4/SvJae * C57BL/6 * MRL)
abnormal immune system physiology J:127292
enlarged cervical lymph nodes J:127292
enlarged spleen J:127292
increased anti-double stranded DNA antibody level J:127292
increased anti-nuclear antigen antibody level J:127292
C4bptm1Raw/C4bptm1Raw
(B6.129-C4bptm1Raw)
increased circulating interleukin-6 level J:244020
C5ar1tm1Cge/C5ar1tm1Cge
(involves: 129S4/SvJae)
abnormal humoral immune response J:35529
impaired neutrophil recruitment J:69177
increased susceptibility to bacterial infection J:69177
C5ar1tm1Cge/C5ar1tm1Cge
(involves: 129S4/SvJae * C57BL/6)
decreased circulating interleukin-6 level J:166640
decreased osteoclast cell number J:166640
C5ar1tm1Raw/C5ar1tm1Raw
(B6.Cg-C5ar1tm1Raw)
immune system phenotype J:139786
increased spleen germinal center number J:139786
C5ar1tm1Song/C5ar1tm1Song
(involves: 129S6/SvEvTac * C57BL/6)
abnormal neutrophil physiology J:184056
C5ar2em1(IMPC)H/C5ar2em1(IMPC)H
(C57BL/6NTac-C5ar2em1(IMPC)H/H)
decreased eosinophil cell number J:211773
increased neutrophil cell number J:211773
C5ar2tm1Cge/C5ar2tm1Cge
(B6.129S1-C5ar2tm1Cge)
abnormal immune cell physiology J:104092
increased inflammatory response J:104092
C8atm1b(EUCOMM)Hmgu/C8atm1b(EUCOMM)Hmgu
(C57BL/6N-C8atm1b(EUCOMM)Hmgu/Tcp)
increased lymphocyte cell number J:211773
C9em1Sjlg/C9+
(C57BL/6-C9em1Sjlg)
impaired complement classical pathway J:301607
C9em1Sjlg/C9em1Sjlg
(C57BL/6-C9em1Sjlg)
decreased interleukin-1 beta secretion J:301607
decreased susceptibility to endotoxin shock J:301607
impaired complement classical pathway J:301607
C9orf72em1Eggn/C9orf72em1Eggn
(involves: C57BL/6)
enlarged cervical lymph nodes J:240357
enlarged spleen J:240357
increased anti-double stranded DNA antibody level J:240357
C9orf72em5Lutzy/C9orf72em5Lutzy
(C57BL/6-C9orf72em5Lutzy)
abnormal macrophage physiology J:101977
abnormal microglial cell physiology J:101977
enlarged lymph nodes J:101977
enlarged spleen J:101977
C9orf72tm1.1(KOMP)Mbp/C9orf72tm1.1(KOMP)Mbp
(C57BL/6N-C9orf72tm1.1(KOMP)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased spleen weight J:211773
C9orf72tm1.1Eggn/C9orf72+
(involves: C57BL/6 * C57BL/6N)
abnormal circulating interleukin level J:240357
decreased circulating interleukin-2 level J:240357
dermatitis J:240357
increased autoantibody level J:240357
increased IgG level J:240357
increased IgM level J:240357
C9orf72tm1.1Eggn/C9orf72tm1.1Eggn
(involves: C57BL/6 * C57BL/6N)
abnormal circulating cytokine level J:240357
abnormal lymphocyte morphology J:240357
abnormal spleen morphology J:240357
brain inflammation J:240357
dermatitis J:240357
enlarged spleen J:240357
increased anti-double stranded DNA antibody level J:240357
increased autoantibody level J:240357
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:240357
increased IgG level J:240357
increased IgM level J:240357
increased leukocyte cell number J:240357
increased neutrophil cell number J:240357
increased splenocyte number J:240357
increased susceptibility to autoimmune disorder J:240357
liver inflammation J:240357
C9orf72tm1Eggn/C9orf72+
(involves: C57BL/6 * C57BL/6N)
dermatitis J:240357
C9orf72tm1Eggn/C9orf72tm1Eggn
(involves: C57BL/6 * C57BL/6N)
abnormal circulating cytokine level J:240357
abnormal lymphocyte morphology J:240357
dermatitis J:240357
enlarged cervical lymph nodes J:240357
enlarged spleen J:240357
increased anti-double stranded DNA antibody level J:240357
increased leukocyte cell number J:240357
increased neutrophil cell number J:240357
increased susceptibility to autoimmune disorder J:240357
C9orf72tm1Lagi/C9orf72tm1Lagi
(involves: C57BL/6 * C57BL/6N)
abnormal celiac lymph node morphology J:232242
abnormal cervical lymph node morphology J:232242
abnormal lymph node cell ratio J:232242
decreased lymphocyte cell number J:232242
enlarged cervical lymph nodes J:232242
enlarged spleen J:232242
increased neutrophil cell number J:232242
Cabin1em1(IMPC)Ccpcz/Cabin1+
(C57BL/6NCrl-Cabin1em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Cabin1tm1.1Che/Cabin1tm1.1Che
(involves: 129S4/SvJae * BALB/c)
abnormal cytokine secretion J:72760
abnormal humoral immune response J:72760
immune system phenotype J:72760
increased IgE level J:72760
increased IgG1 level J:72760
increased IgG2b level J:72760
Cabp1tm1b(EUCOMM)Wtsi/Cabp1tm1b(EUCOMM)Wtsi
(C57BL/6N-Cabp1tm1b(EUCOMM)Wtsi/H)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Cacna1atg-6J/Cacna1atg-6J
(involves: BALB/cByJ * C57BL/6J)
abnormal spleen red pulp morphology J:82238
thymus atrophy J:82238
Cacna1cem1(IMPC)Mbp/Cacna1c+
(C57BL/6N-Cacna1cem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cacna1ctm2Itl/Cacna1c+
(involves: 129S6/SvEvTac * C57BL/6NTac)
dermatitis J:201506
Cacna1itm1b(KOMP)Wtsi/Cacna1itm1b(KOMP)Wtsi
(C57BL/6N-Cacna1itm1b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Cacna2d1em1(IMPC)Mbp/Cacna2d1em1(IMPC)Mbp
(C57BL/6N-Cacna2d1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
increased monocyte cell number J:211773
small spleen J:211773
Cacna2d2du-td/Cacna2d2du-td
(involves: DBA/2J)
abnormal thymus involution J:12166
Cacna2d2em1(IMPC)Mbp/Cacna2d2+
(C57BL/6N-Cacna2d2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Cacna2d2em1(IMPC)Mbp/Cacna2d2em1(IMPC)Mbp
(C57BL/6N-Cacna2d2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Cacna2d2tm1Svi/Cacna2d2tm1Svi
(involves: 129S1/Sv * C57BL/6J)
rhinitis J:92396
thymus hypoplasia J:92396
Cacnb3tm1Acv/Cacnb3tm1Acv
(involves: 129S1/Sv * 129X1/SvJ)
abnormal CD4-positive, alpha-beta T cell physiology J:115345
abnormal interleukin secretion J:115345
decreased interferon-gamma secretion J:115345
Cacnb4lh/Cacnb4lh
(B6EiC3Sn a/A-Cacnb4lh/J)
abnormal CD4-positive, alpha-beta T cell physiology J:115345
abnormal interleukin secretion J:115345
abnormal lymph node morphology J:5281
abnormal Peyer's patch germinal center morphology J:5281
abnormal thymus involution J:5281
absent thymus corticomedullary boundary J:5281
decreased double-positive T cell number J:115345
decreased interferon-gamma secretion J:115345
decreased interleukin-2 secretion J:115345
decreased lymphocyte cell number J:5281
decreased Peyer's patch number J:5281
enlarged lymph nodes J:5281
small Peyer's patches J:5281
small spleen J:5281
small thymus J:5281
Cacnb4lh/Cacnb4lh
(BALB/cGn-Cacnb4lh)
abnormal thymus involution J:12166
increased length of allograft survival J:5766
Cacnb4lh/Cacnb4lh
(involves: BALB/cGn)
increased IgG1 level J:5883
Cactinem1(IMPC)Ccpcz/Cactin+
(C57BL/6NCrl-Cactinem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
CacybpGT(OST39970)Lex/CacybpGT(OST39970)Lex
(involves: 129S5/SvEvBrd)
abnormal spleen white pulp morphology J:110899
abnormal T cell morphology J:110899
decreased thymocyte number J:110899
small thymus medulla J:110899
spleen hypoplasia J:110899
thymus hypoplasia J:110899
Cacybptm1b(EUCOMM)Wtsi/Cacybp+
(C57BL/6N-Cacybptm1b(EUCOMM)Wtsi/Tcp)
increased neutrophil cell number J:211773
Cadm1Gt(Ayu21-W34)Imeg/Cadm1Gt(Ayu21-W34)Imeg
(involves: C57BL/6 * CBA/JNCrlj)
abnormal T cell differentiation J:178612
abnormal T cell receptor V(D)J recombination J:178612
decreased CD4-positive, alpha-beta T cell number J:178612
decreased CD8-positive, alpha-beta T cell number J:178612
decreased interferon-gamma secretion J:178612
decreased interleukin-2 secretion J:178612
decreased interleukin-4 secretion J:178612
decreased T cell proliferation J:178612
increased double-positive T cell number J:178612
Cadps2em1(IMPC)Rbrc/Cadps2em1(IMPC)Rbrc
(C57BL/6NJcl-Cadps2em1(IMPC)Rbrc/Rbrc)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Calb1em1(IMPC)Ccpcz/Calb1em1(IMPC)Ccpcz
(C57BL/6NCrl-Calb1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
small spleen J:211773
Calcrtm1Dgal/Calcr+
Iapptm1Sgm/Iapp+

(involves: 129P2/OlaHsd)
increased osteoclast cell number J:88964
Calcrtm1Rda/Calcrtm1Rda
Tg(CMV-cre)1Cgn/0

(B6.Cg-Calcrtm1Rda Tg(CMV-cre)1Cgn)
abnormal osteoclast physiology J:150982
Calcrltm1Kmca/Calcrltm1Kmca
(129S6/SvEvTac-Calcrltm1Kmca)
abnormal lymph organ development J:130930
Calcrltm1Kmca/Calcrltm1Kmca
(involves: 129S6/SvEvTac)
decreased uterine NK cell number J:201446
Caluem1(IMPC)Tcp/Calu+
(C57BL/6N-Caluem1(IMPC)Tcp/Tcp)
small lymph nodes J:211773
Camk1dem1(IMPC)Mbp/Camk1dem1(IMPC)Mbp
(C57BL/6NCrl-Camk1dem1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Camk2gtm1.1Irt/Camk2gtm1.1Irt
(involves: C57BL/6 * C57BL/6J)
decreased macrophage apoptosis J:154647
Camk2gtm1.1Irt/Camk2gtm1.1Irt
(involves: C57BL/6J)
increased susceptibility to colitis induced morbidity/mortality J:243363
increased susceptibility to induced colitis J:243363
Camk4em1(IMPC)Ccpcz/Camk4em1(IMPC)Ccpcz
(C57BL/6N-Camk4em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small spleen J:211773
Camk4tm1Tch/Camk4tm1Tch
(B6.129X1-Camk4tm1Tch)
abnormal osteoclast differentiation J:129599
decreased osteoclast cell number J:129599
Camltm1Rjb/Camltm2Rjb
Tg(Lck-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
decreased single-positive T cell number J:100536
decreased thymocyte number J:100536
increased T cell apoptosis J:100536
Camltm1Rjb/Camltm2Rjb
Tg(Lck-cre)1Cwi/0
Tg(TcraTcrb)1100Mjb/0

(involves: 129 * C57BL/6 * DBA/2)
abnormal negative T cell selection J:100536
abnormal positive T cell selection J:100536
decreased thymocyte number J:100536
Camptm1.1Jimw/Camptm1.1Jimw
(involves: C57BL/6)
decreased dendritic cell number J:199611
Camptm1Rlg/Camp+
(involves: 129X1/SvJ * C57BL/6)
increased susceptibility to bacterial infection J:72924
Camptm1Rlg/Camptm1Rlg
(involves: 129X1/SvJ * C57BL/6)
increased incidence of corneal inflammation J:199719
increased neutrophil cell number J:199719
increased susceptibility to bacterial infection J:72924
increased susceptibility to fungal infection J:199719
Camptm1Rlg/Camptm1Rlg
(129X1(B6)-Camptm1Rlg/Kini)
increased susceptibility to bacterial infection J:109553
increased susceptibility to bacterial infection induced morbidity/mortality J:109553
Camsap3tm1a(EUCOMM)Wtsi/Camsap3tm1a(EUCOMM)Wtsi
(C57BL/6N-Camsap3tm1a(EUCOMM)Wtsi/Wtsi)
increased gamma-delta T cell number J:211773
increased leukocyte cell number J:211773
increased neutrophil cell number J:211773
Cand1em1(IMPC)Mbp/Cand1+
(C57BL/6NCrl-Cand1em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Canxem1(IMPC)Ccpcz/Canx+
(C57BL/6NCrl-Canxem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Canxem1(IMPC)Ccpcz/Canxem1(IMPC)Ccpcz
(C57BL/6NCrl-Canxem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
CanxGt(KST286)Byg/CanxGt(KST286)Byg
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:164553
Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
(involves: C57BL/6J * C57BL/6N)
eye inflammation J:234044
increased susceptibility to infection J:234044
Capgtm1Djk/Capgtm1Djk
(involves: 129S4/SvJae)
abnormal macrophage physiology J:86517
impaired macrophage phagocytosis J:86517
Capgtm1Djk/Capgtm1Djk
(involves: 129S4/SvJae * BALB/c * C57BL/6)
abnormal dendritic cell physiology J:86277
impaired macrophage phagocytosis J:86277
impaired neutrophil chemotaxis J:86277
increased susceptibility to bacterial infection J:86277
Capgtm1Djk/Capgtm1Djk
Gsntm1Djk/Gsntm1Djk

(involves: 129S4/SvJae)
abnormal macrophage physiology J:86517
impaired macrophage phagocytosis J:86517
Capn1tm1Dgen/Capn1tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6)
abnormal leukocyte adhesion J:183585
Capn5tm1Nde/Capn5tm1Nde
(involves: 129X1/SvJ * C57BL/6J)
immune system phenotype J:87678
CapopNOD/CapopNOD
(involves: C57BL/6 * NOD)
decreased T cell apoptosis J:68151
Capza1em1(IMPC)Tcp/Capza1em1(IMPC)Tcp
(C57BL/6NCrl-Capza1em1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Capza2tm1b(KOMP)Wtsi/Capza2tm1b(KOMP)Wtsi
(C57BL/6N-Capza2tm1b(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
Car2tm1(KOMP)Vlcg/Car2tm1(KOMP)Vlcg
(involves: C57BL/6 * C57BL/6NTac)
increased susceptibility to bacterial infection J:216402
pyelonephritis J:216402
Car6em1(IMPC)Ccpcz/Car6em1(IMPC)Ccpcz
(C57BL/6NCrl-Car6em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased NK cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased eosinophil cell number J:211773
Car6tm1Pwp/Car6tm1Pwp
(B6.129S6-Car6tm1Pwp)
abnormal Peyer's patch follicle morphology J:172854
Car9tm1Lex/Car9tm1Lex
(B6;129S5-Car9tm1Lex/Mmucd)
increased mature B cell number J:171883
Card6tm1.1Aldu/Card6tm1.1Aldu
(B6.129P2-Card6tm1.1Aldu)
immune system phenotype J:132634
Card9tm1Jrld/Card9tm1Jrld
(involves: 129P2/OlaHsd)
abnormal dendritic cell physiology J:111706
increased susceptibility to fungal infection J:111706
Card9tm1Tks/Card9tm1Tks
(B6.129-Card9tm1Tks)
abnormal chemokine secretion J:141143
abnormal cytokine secretion J:122394
abnormal dendritic cell physiology J:122394
abnormal macrophage physiology J:141143, J:122394
decreased interleukin-6 secretion J:160680
decreased interleukin-10 secretion J:160680
decreased interleukin-12b secretion J:160680
decreased interleukin-23 secretion J:160680
decreased tumor necrosis factor secretion J:160680
immune system phenotype J:122394
increased susceptibility to bacterial infection J:122394
Card9tm1Xlin/Card9tm1Xlin
(involves: 129/Sv * C57BL/6)
abnormal cytokine level J:117799
abnormal innate immunity J:117799
abnormal macrophage physiology J:117799
increased susceptibility to bacterial infection J:117799
Card11em1(IMPC)Ccpcz/Card11em1(IMPC)Ccpcz
(C57BL/6NCrl-Card11em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased effector memory T-helper cell number J:211773
decreased spleen weight J:211773
enlarged thymus J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased T cell number J:211773
increased T-helper cell number J:211773
small spleen J:211773
Card11em1Welu/Card11+
(involves: C57BL/6)
decreased marginal zone B cell number J:292926
decreased transitional stage T1 B cell number J:292926
decreased transitional stage T3 B cell number J:292926
impaired humoral immune response J:292926
increased transitional stage T2 B cell number J:292926
Card11em1Welu/Card11em1Welu
(involves: C57BL/6)
abnormal B cell differentiation J:292926
abnormal germinal center B cell morphology J:292926
abnormal plasma cell differentiation J:292926
decreased B cell proliferation J:292926
decreased B-1 B cell number J:292926
decreased B-1a cell number J:292926
decreased germinal center B cell number J:292926
decreased IgG level J:292926
decreased IgM level J:292926
decreased marginal zone B cell number J:292926
decreased pre-B cell number J:292926
decreased transitional stage T1 B cell number J:292926
decreased transitional stage T3 B cell number J:292926
impaired humoral immune response J:292926
increased follicular B cell number J:292926
increased transitional stage T2 B cell number J:292926
Card11em2Welu/Card11+
(involves: C57BL/6)
increased B-1 B cell number J:292926
increased marginal zone B cell number J:292926
Card11em2Welu/Card11em2Welu
(involves: C57BL/6)
abnormal plasma cell differentiation J:292926
decreased mature B cell number J:292926
enlarged spleen J:292926
increased B cell proliferation J:292926
increased B-1a cell number J:292926
increased B-1b cell number J:292926
increased germinal center B cell number J:292926
increased marginal zone B cell number J:292926
increased pre-B cell number J:292926
increased transitional stage T2 B cell number J:292926
Card11em3Welu/Card11em3Welu
(Not Specified)
decreased B-1 B cell number J:292926
decreased marginal zone B cell number J:292926
Card11m1Btlr/Card11m1Btlr
(C57BL/6J-Card11m1Btlr)
abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology J:149767
abnormal cytokine secretion J:149767
abnormal cytotoxic T cell physiology J:139069
abnormal double-negative T cell morphology J:149767, J:139069
abnormal NK cell physiology J:139069
abnormal T cell activation J:139069
decreased B cell proliferation J:149767, J:139069
decreased B-1 B cell number J:149767, J:139069
decreased gamma-delta T cell number J:149767, J:139069
decreased IgG1 level J:149767, J:139069
decreased IgG2a level J:149767, J:139069
decreased IgG2b level J:149767, J:139069
decreased IgG2c level J:149767
decreased IgG3 level J:149767, J:139069
decreased IgM level J:149767, J:139069
decreased immunoglobulin level J:139069
decreased interferon-gamma secretion J:139069
decreased interleukin-2 secretion J:139069
decreased mature B cell number J:149767, J:139069
decreased memory T cell number J:149767, J:139069
decreased NK cell number J:149767, J:139069
decreased NK T cell number J:149767, J:139069
decreased regulatory T cell number J:149767
decreased T cell proliferation J:149767, J:139069
dermatitis J:149767, J:139069
immune system phenotype J:139069
Card11M2Btlr/Card11M2Btlr
(involves: C57BL/6J)
decreased IgM level J:198555
Card11m3Btlr/Card11m3Btlr
(C57BL/6J-Card11m3Btlr)
increased B-1a cell number J:221487
Card11M4Btlr/Card11+
(C57BL/6J-Card11M4Btlr)
decreased B-1a cell number J:254856
increased B-1b cell number J:254856
Card11M4Btlr/Card11M4Btlr
(C57BL/6J-Card11M4Btlr)
decreased B-1a cell number J:254856
decreased IgM level J:254856
impaired humoral immune response J:254856
increased B-1b cell number J:254856
Card11M5Btlr/Card11+
(C57BL/6J-Card11M5Btlr)
decreased IgM level J:254879
impaired humoral immune response J:254879
increased B-1 B cell number J:254879
increased B-1a cell number J:254879
Card11M5Btlr/Card11M5Btlr
(C57BL/6J-Card11M5Btlr)
decreased IgM level J:254879
impaired humoral immune response J:254879
increased B-1 B cell number J:254879
increased B-1a cell number J:254879
Card11M6Btlr/Card11M6Btlr
(C57BL/6J-Card11M6Btlr)
increased alpha-beta T cell number J:272116
Card11M7Btlr/Card11M7Btlr
(C57BL/6J-Card11M7Btlr)
abnormal T cell differentiation J:274762
decreased B cell number J:274762
decreased B-1 B cell number J:274762
decreased central memory CD4-positive, alpha-beta T cell number J:274762
decreased effector memory CD4-positive, alpha-beta T cell number J:274762
decreased effector memory CD8-positive, alpha-beta T cell number J:274762
increased CD4-positive, alpha-beta T cell number J:274762
increased CD8-positive, alpha-beta T cell number J:274762
increased T cell number J:274762
Card11m8Btlr/Card11m8Btlr
(C57BL/6J-Card11m8Btlr)
abnormal B cell differentiation J:274940
decreased B cell number J:274940
decreased B-1a cell number J:274940
decreased effector memory CD8-positive, alpha-beta T cell number J:274940
decreased IgG level J:274940
decreased IgM level J:274940
decreased response to antigen J:274940
impaired humoral immune response J:274940
increased B-1b cell number J:274940
increased CD4-positive, alpha-beta T cell number J:274940
increased CD8-positive, alpha-beta T cell number J:274940
increased NK T cell number J:274940
increased T cell number J:274940
Card11tm1.1Litt/Card11tm1.1Litt
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Tg(TcraTcrb)425Cbn/?

(involves: 129/Sv * 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal T cell activation J:180410
Card11tm1.1Litt/Card11tm1.1Litt
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129P2/OlaHsd * 129X1/SvJ)
abnormal T cell activation J:180410
immune system phenotype J:180410
respiratory system inflammation J:180410
Card11tm1Litt/Card11tm1Litt
(involves: 129P2/OlaHsd)
abnormal B cell proliferation J:89322
abnormal double-negative T cell morphology J:89322
abnormal T cell activation J:89322
abnormal T cell differentiation J:89322
abnormal T cell proliferation J:89322
absent B-1a cells J:89322
decreased IgA level J:89322
decreased IgG1 level J:89322
decreased IgG2b level J:89322
decreased IgG3 level J:89322
decreased IgM level J:89322
decreased immunoglobulin level J:89322
Card11tm1Pngr/Card11tm1Pngr
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:84036
abnormal B cell physiology J:84036
abnormal interleukin-2 secretion J:84036
abnormal lymphocyte morphology J:84036
abnormal T cell activation J:84036
absent B-1a cells J:84036
decreased B cell proliferation J:84036
decreased IgA level J:84036
decreased IgE level J:84036
decreased IgG1 level J:84036
decreased IgG2a level J:84036
decreased IgG2b level J:84036
decreased IgG3 level J:84036
decreased IgG level J:84036
decreased IgM level J:84036
decreased immunoglobulin level J:84036
decreased NK cell number J:84036
Card11tm1Pngr/Card11tm1Pngr
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:122394
Card11tm1Vmd/Card11+
(involves: 129S6/SvEvTac * C57BL/6N)
decreased B cell proliferation J:95800
Card11tm1Vmd/Card11tm1Vmd
(involves: 129S6/SvEvTac * C57BL/6N)
abnormal B cell physiology J:95800
absent immature B cells J:95800
decreased B cell proliferation J:95800
decreased IgA level J:95800
decreased IgG1 level J:95800
decreased IgG2a level J:95800
decreased IgG2b level J:95800
decreased IgG3 level J:95800
decreased IgG level J:95800
decreased IgM level J:95800
decreased T cell proliferation J:95800
Card11tm1Xav/Card11tm1Xav
(involves: 129 * C57BL/6)
abnormal T cell activation J:132226
abnormal T-helper 2 cell differentiation J:132226
decreased circulating interleukin-4 level J:132226
decreased circulating interleukin-5 level J:132226
decreased IgE level J:132226
increased CD4-positive, alpha-beta T cell number J:132226
increased CD8-positive, alpha-beta T cell number J:132226
lung inflammation J:132226
Card11unm/Card11unm
(C57BL/6JSfdAnu-Card11unm/Anu)
abnormal B cell differentiation J:84042
abnormal immune system physiology J:84042
abnormal T cell activation J:84042
decreased B-1 B cell number J:84042
decreased IgG3 level J:84042
decreased IgM level J:84042
decreased immunoglobulin level J:84042
dermatitis J:84042
erythroderma J:84042
increased IgE level J:84042
increased immunoglobulin level J:84042
increased inflammatory response J:84042
lymph node hyperplasia J:84042
spleen hyperplasia J:84042
Card14em1Tshu/Card14em1Tshu
(C57BL/6-Card14em1Tshu)
decreased susceptibility to chemically induced skin inflammation J:289239
Card14em2Tshu/Card14+
(involves: C57BL/6)
abnormal gamma-delta T cell number J:289239
increased alpha-beta T cell number J:289239
skin inflammation J:289239
Card14em3Tshu/Card14+
(involves: C57BL/6)
skin inflammation J:289239
Card14em3Tshu/Card14+
Il17atm1Cdon/Il17atm1Cdon

(involves: C57BL/6)
decreased inflammatory response J:289239
Card14em9Lutzy/Card14+
(C57BL/6J-Card14em9Lutzy/J)
skin inflammation J:262723
Card14tm1Lex/Card14tm1Lex
(B6.129S-Card14tm1Lex)
decreased susceptibility to chemically induced skin inflammation J:253409
Card19tm1Rwen/Card19tm1Rwen
(involves: 129P2/OlaHsd * C57BL/6)
decreased autoantibody level J:336763
immune system phenotype J:336763
Card19tm1Rwen/Card19tm1Rwen
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell activation J:336763
Card19tm1Rwen/Card19tm1Rwen
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JSfd)
decreased B cell number J:336763
decreased B cell proliferation J:336763
increased B cell apoptosis J:336763
increased B cell number J:336763
Carm1tm1b(EUCOMM)Hmgu/Carm1+
(C57BL/6N-Carm1tm1b(EUCOMM)Hmgu/Nju)
decreased lymphocyte cell number J:211773
Carm1tm1Mtb/Carm1tm1Mtb
(involves: 129S6/SvEvTac)
arrested T cell differentiation J:159958
Carm1tm2.1Mtb/Carm1tm2.1Mtb
(involves: 129S4/SvJaeSor * 129S6/SvEvTac * Black Swiss)
arrested T cell differentiation J:159958
thymus hypoplasia J:159958
carmelo/carmelo
(involves: 129S1/SvImJ * C57BL/6J)
decreased susceptibility to parasitic infection induced morbidity/mortality J:220661
Carmil2bas/Carmil2bas
(involves: C3HeB/FeJ * C57BL/6)
decreased interferon-gamma secretion J:205441
decreased interleukin-2 secretion J:205441
decreased regulatory T cell number J:205441
decreased T cell proliferation J:205441
enlarged thymus J:205441
immune system phenotype J:205441
Carmil2bas/Carmil2tm1a(KOMP)Mbp
(involves: C3HeB/FeJ * C57BL/6 * C57BL/6N)
decreased interleukin-2 secretion J:205441
decreased regulatory T cell number J:205441
decreased T cell proliferation J:205441
Carmil3em1(IMPC)Mbp/Carmil3em1(IMPC)Mbp
(C57BL/6N-Carmil3em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Cartpttm1Hmh/Cartpttm1Hmh
(Not Specified)
abnormal osteoclast morphology J:97566
increased osteoclast cell number J:97566
Casp1tm1Flv/Casp1tm1Flv
Casp4del/Casp4del

(involves: 129S2/SvPas * C57BL/6)
abnormal cytokine secretion J:24258
decreased circulating interferon-gamma level J:115310
decreased interferon-gamma secretion J:115310
decreased interleukin-1 alpha secretion J:24258
decreased interleukin-1 beta secretion J:24258
decreased interleukin-6 secretion J:24258
decreased interleukin-18 secretion J:115310
decreased susceptibility to endotoxin shock J:43088
decreased susceptibility to experimental autoimmune encephalomyelitis J:57101
decreased thymocyte apoptosis J:24258
decreased tumor necrosis factor secretion J:24258
impaired neutrophil chemotaxis J:124226
increased susceptibility to bacterial infection J:117251
Casp1tm1Flv/Casp1tm1Flv
Casp4del/Casp4del

(B6.129S2-Casp1tm1Flv)
decreased interleukin-1 beta secretion J:160545
increased susceptibility to induced colitis J:173245
Casp1tm1Flv/Casp1tm1Flv
Casp4del/Casp4del
Il1r1tm1Imx/Il1r1tm1Imx

(involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6)
decreased susceptibility to endotoxin shock J:43088
Casp1tm1Flv/Casp1tm1Flv
Casp4del/Casp4del
Slc11a1r/Slc11a1r

(involves: 129S2/SvPas)
increased susceptibility to bacterial infection J:124378
Casp1tm1Flv/Casp1tm1Flv
Casp4del/Casp4del
Slc11a1s/Slc11a1s

(B6.129S2-Casp1tm1Flv)
cecum inflammation J:124378
increased susceptibility to bacterial infection J:124378
Casp1tm1Sesh/Casp1+
Casp4del/Casp4+

(involves: 129S2/SvPas * C57BL/6)
decreased interleukin-1 beta secretion J:22964
Casp1tm1Sesh/Casp1+
Casp4del/Casp4+

(involves: 129S1/SvImJ * 129S2/SvPas * NOD)
abnormal macrophage physiology J:99748
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del

(involves: 129S2/SvPas * C57BL/6)
abnormal inflammatory response J:80568
abnormal macrophage physiology J:22964
abnormal neutrophil physiology J:80568
decreased circulating interleukin-1 alpha level J:22964
decreased circulating interleukin-1 beta level J:22964
decreased circulating interleukin-6 level J:22964
decreased circulating tumor necrosis factor level J:22964
decreased interleukin-1 alpha secretion J:22964
decreased interleukin-1 beta secretion J:88212, J:22964
decreased susceptibility to endotoxin shock J:22964, J:40691
decreased T cell apoptosis J:40691
immune system phenotype J:40691
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del

(NOD.129S2(B6)-Casp1tm1Sesh Casp4del/LtJ)
decreased interleukin-1 alpha secretion J:87250
decreased interleukin-1 beta secretion J:87250
decreased interleukin-18 secretion J:87250
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del

(C3N.129S2-Casp1tm1Sesh Casp4del)
abnormal response to infection J:86761
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del

(B10.Cg-Casp1tm1Sesh Casp4del H2r H2-T18b)
decreased inflammatory response J:63488
decreased susceptibility to bacterial infection J:63488
decreased susceptibility to bacterial infection induced morbidity/mortality J:63488
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del

(involves: 129 * 129S2/SvPas * C57BL/6)
decreased interleukin-1 beta secretion J:50775
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del

(C3.129S2-Casp1tm1Sesh Casp4del)
abnormal macrophage physiology J:136368
decreased interleukin-1 beta secretion J:136368
increased susceptibility to bacterial infection J:136368
increased susceptibility to bacterial infection induced morbidity/mortality J:136368
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del

(B6.129S2(NOD)-Casp1tm1Sesh Casp4del)
decreased circulating interleukin-1 alpha level J:193522
decreased circulating interleukin-1 beta level J:193522
decreased circulating interleukin-18 level J:193522
decreased interleukin-1 alpha secretion J:193522
decreased interleukin-1 beta secretion J:193522
decreased interleukin-18 secretion J:193522
decreased macrophage apoptosis J:193522
decreased susceptibility to endotoxin shock J:193522
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del
Slc11a1r/Slc11a1s

(involves: 129/Sv * 129S2/SvPas * C57BL/6)
increased susceptibility to bacterial infection J:112400
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del
Slc11a1s/Slc11a1s

(B6.129S2-Casp1tm1Sesh Casp4del)
abnormal macrophage physiology J:112400
increased susceptibility to bacterial infection J:112400
Casp1tm1Sesh/Casp1tm1Sesh
Casp4del/Casp4del
Tg(Casp4)#Gne/0

(involves: 129S2/SvPas * C57BL/6 * NOD/ShiLtJ)
decreased circulating interleukin-1 beta level J:193522
decreased circulating interleukin-18 level J:193522
decreased interleukin-1 alpha secretion J:193522
decreased interleukin-1 beta secretion J:193522
decreased interleukin-18 secretion J:193522
decreased macrophage apoptosis J:193522
decreased susceptibility to endotoxin shock J:193522
Casp1tm1Sesh/Casp1tm1Sesh
Nlrp1aNeut1/Nlrp1aNeut1

(involves: 129S2/SvPas * C57BL/6)
immune system phenotype J:191055
increased circulating interleukin-18 level J:191055
Casp2tm1Vaux/Casp2tm1Vaux
Casp9tm1Flv/Casp9tm1Flv

(involves: 129S1/Sv * C57BL/6)
abnormal T cell physiology J:91156
Casp2tm1Yuan/Casp2tm1Yuan
(involves: 129S4/SvJae * C57BL/6J * DBA/2)
abnormal B cell apoptosis J:47601
Casp3tm1Flv/Casp3tm1Flv
(involves: 129S1/Sv * C57BL/6)
abnormal bone marrow development J:94703
abnormal osteoclast physiology J:94703
decreased thymocyte number J:36821
immune system phenotype J:36821
Casp3tm1Flv/Casp3tm1Flv
Casp7tm1Flv/Casp7+

(B6.129S-Casp3tm1Flv Casp7tm1Flv)
decreased thymocyte apoptosis J:105496
Casp3tm1Flv/Casp3tm1Flv
Casp7tm1Flv/Casp7tm1Flv

(B6.129S-Casp3tm1Flv Casp7tm1Flv)
decreased thymocyte apoptosis J:105496
Casp3tm1Flv/Casp3tm1Flv
Tg(Scgb1a1-rtTA,tetO-Ifng)14Eli/0

(involves: 129S1/Sv * C57BL/6 * CBA)
increased lymphocyte cell number J:100854
increased macrophage cell number J:100854
increased neutrophil cell number J:100854
Casp3tm1Mak/Casp3tm1Mak
(B6.129P2-Casp3tm1Mak)
decreased inflammatory response J:97650, J:179279
Casp3tm1Mak/Casp3tm1Mak
Tg(TcrLCMV)327Sdz/0

(B6.Cg-Casp3tm1Mak Tg(TcrLCMV)327Sdz)
abnormal CD8-positive, alpha beta T cell morphology J:97650
Casp4tm1.1Vmd/Casp4tm1.1Vmd
(involves: C57BL/6)
decreased circulating interleukin-1 alpha level J:193522
decreased circulating interleukin-1 beta level J:193522
decreased circulating interleukin-18 level J:193522
decreased interleukin-1 alpha secretion J:193522
decreased interleukin-1 beta secretion J:193522
decreased macrophage apoptosis J:193522
decreased susceptibility to endotoxin shock J:193522
Casp4tm1Yuan/Casp4tm1Yuan
(involves: 129S4/SvJae * C57BL/6J * DBA/2)
decreased circulating interleukin-1 alpha level J:46167
decreased circulating interleukin-1 beta level J:46167
decreased susceptibility to endotoxin shock J:46167
Casp4tm1Yuan/Casp4tm1Yuan
(B6.129S4(D2)-Casp4tm1Yuan/J)
decreased interleukin-1 beta secretion J:270123
decreased interleukin-18 secretion J:270123
Casp7tm1.1Acau/Casp7tm1.1Acau
(B6.Cg-Casp7tm1.1Acau)
immune system phenotype J:179279
Casp7tm1Flv/Casp7tm1Flv
(B6.129S6-Casp7tm1Flv)
immune system phenotype J:105496
Casp8em1Hbz/Casp8em1Hbz
(involves: C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:342732
enlarged spleen J:342732
Casp8em1Hbz/Casp8em1Hbz
Mlklem1Hbz/Mlklem1Hbz

(involves: C57BL/6)
decreased B cell number J:342732
decreased leukocyte cell number J:342732
decreased lymphocyte cell number J:342732
decreased mature B cell number J:342732
decreased T cell number J:342732
enlarged spleen J:342732
increased CD11b-high dendritic cell number J:342732
increased granulocyte number J:342732
increased macrophage cell number J:342732
Casp8em1Hbz/Casp8em1Hbz
Ripk1em1Hbz/Ripk1em1Hbz
Ripk3tm1Xidw/Ripk3tm1Xidw

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased leukocyte cell number J:342732
decreased lymphocyte cell number J:342732
decreased mature B cell number J:342732
decreased T cell number J:342732
Casp8em1Hbz/Casp8em1Hbz
Ripk3tm1Xidw/Ripk3tm1Xidw

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased B cell number J:342732
decreased leukocyte cell number J:342732
decreased lymphocyte cell number J:342732
decreased mature B cell number J:342732
decreased T cell number J:342732
enlarged spleen J:342732
increased CD11b-high dendritic cell number J:342732
increased granulocyte number J:342732
increased macrophage cell number J:342732
Casp8m1Btlr/Casp8m1Btlr
(C57BL/6J-Casp8m1Btlr)
decreased CD4-positive, alpha-beta T cell number J:255007
decreased CD8-positive, naive alpha-beta T cell number J:255007
decreased T cell number J:255007
increased CD8-positive, alpha-beta T cell number J:255007
increased effector memory CD4-positive, alpha-beta T cell number J:255007
Casp8M2Btlr/Casp8M2Btlr
(C57BL/6J-Casp8M2Btlr)
increased effector memory CD8-positive, alpha-beta T cell number J:272851
Casp8tm1.1Raz/Casp8tm1.1Raz
Otulinem1Gvl/Otulinem1Gvl
Ripk3tm1Vmd/Ripk3tm1Vmd

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J)
enlarged lymph nodes J:312394
immune system phenotype J:312394
Casp8tm1.1Raz/Casp8tm1.1Raz
Ripk3tm1Vmd/Ripk3tm1Vmd

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
abnormal macrophage physiology J:170815
decreased macrophage apoptosis J:170815
decreased thymocyte apoptosis J:170814
enlarged axillary lymph nodes J:170815
enlarged cervical lymph nodes J:170815
enlarged lymph nodes J:170814
enlarged spleen J:170815, J:170814
enlarged thymus J:170814
immune system phenotype J:170815
increased B cell number J:170815
increased inflammatory response J:170815
increased leukocyte cell number J:170815
increased spleen white pulp amount J:170815
increased T cell number J:170815, J:170814
large lymphoid organs J:170814
lymph node hyperplasia J:170815
Casp8tm1.1Vmd/Casp8tm1.1Vmd
Ripk3tm2Vmd/Ripk3tm2Vmd

(involves: C57BL/6N)
enlarged lymph nodes J:209137
enlarged spleen J:209137
increased T cell number J:209137
Casp8tm1Clie/Casp8tm1Clie
Tg(Alb1-cre)7Gsc/0

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
liver inflammation J:218665
Casp8tm1Hed/Casp8tm1Hed
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd)
abnormal adaptive immunity J:116713
abnormal immunoglobulin level J:116713
decreased B cell number J:116713
decreased B cell proliferation J:116713
decreased B-1 B cell number J:116713
decreased marginal zone B cell number J:116713
spleen hypoplasia J:116713
Casp8tm1Hed/Casp8tm1Hed
Tg(KRT14-cre)1Efu/0

(Not Specified)
abnormal T cell physiology J:167299
dermatitis J:167299
increased IgE level J:167299
increased IgG1 level J:167299
increased mast cell number J:167299
Casp8tm1Raz/Casp8tm1Raz
Tg(Lck-cre)548Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal CD8-positive, alpha-beta T cell physiology J:82759
abnormal lymphocyte morphology J:107455
abnormal T cell activation J:107455
abnormal T cell morphology J:82759
abnormal T cell physiology J:107455
abnormal T cell proliferation J:107455
abnormal T cell subpopulation ratio J:107455, J:82759
decreased CD4-positive, alpha-beta T cell number J:82759
decreased CD8-positive, alpha-beta T cell number J:82759
decreased leukocyte cell number J:107455
decreased T cell apoptosis J:82759
decreased T cell number J:82759
decreased T cell proliferation J:82759
enlarged lymph nodes J:107455
enlarged spleen J:107455
increased B cell number J:107455
increased lymphocyte cell number J:107455
increased T cell number J:107455
lymphoid hyperplasia J:107455
Casp8tm1Wll/Casp8tm1.1Yuan
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129S1/Sv * 129X1/SvJ * MF1)
abnormal macrophage differentiation J:92722
Casp9tm1Flv/Casp9tm1Flv
(involves: 129S1/Sv * C57BL/6)
abnormal thymocyte apoptosis J:49088
decreased T cell apoptosis J:91156
immune system phenotype J:49088
Casp9tm1Mak/Casp9tm1Mak
(either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1))
abnormal splenocyte apoptosis J:49087
abnormal thymocyte apoptosis J:49087
immune system phenotype J:49087
Casp12tm1Dwni/Casp12tm1Dwni
(involves: 129S1/SvImJ * C57BL/6)
decreased susceptibility to bacterial infection J:144912
decreased susceptibility to bacterial infection induced morbidity/mortality J:144912
increased circulating interleukin-18 level J:144912
increased interferon-gamma secretion J:144912
increased interleukin-1 beta secretion J:144912
increased susceptibility to endotoxin shock J:144912
Casp14em1(IMPC)Ccpcz/Casp14em1(IMPC)Ccpcz
(C57BL/6N-Casp14em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
CasrNuf/CasrNuf
(involves: 102/El * C3H/He)
tongue inflammation J:92612
Casz1Gt(CJ0565)Wtsi/Casz1Gt(CJ0565)Wtsi
(involves: 129P2/OlaHsd * C57BL/6)
abnormal lymphatic vessel morphology J:242127
enlarged lymphatic vessel J:242127
Cav1tm1Mls/Cav1tm1Mls
(involves: 129/Sv * C57BL/6 * SJL)
abnormal chemokine secretion J:115914
abnormal cytokine level J:115914
abnormal macrophage physiology J:115914
abnormal neutrophil physiology J:139304
abnormal osteoclast morphology J:141361
decreased susceptibility to endotoxin shock J:139304
impaired neutrophil recruitment J:115914
increased circulating CXCL10 level J:115914
increased circulating interferon-gamma level J:115914
increased circulating interleukin-6 level J:115914
increased circulating tumor necrosis factor level J:115914
increased susceptibility to bacterial infection J:115914
increased susceptibility to bacterial infection induced morbidity/mortality J:115914
lung inflammation J:87282
Cav1tm1Mls/Cav1tm1Mls
Cav3tm1Mls/Cav3tm1Mls

(involves: 129/Sv * C57BL/6J * SJL)
heart inflammation J:77372
Cbfa2t2tm1Swh/Cbfa2t2tm1Swh
(either: B6.129S6-Cbfa2t2tm1Swh or (involves: 129S6/SvEvTac * C57BL/6))
small intestinal inflammation J:102172
Cbfa2t3tm1.1Swh/Cbfa2t3tm1.1Swh
(involves: 129S6/SvEvTac * C57BL/6 * FVB/N)
abnormal myelopoiesis J:140967
decreased immature B cell number J:140967
enlarged spleen J:140967
Cbfbtm1Itan/Cbfbtm1Itan
Rr94tm3.1Litt/Rr94tm3.1Litt
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N)
abnormal double-positive T cell morphology J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
decreased double-positive T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
increased double-positive T cell number J:158962
Cbfbtm1Itan/Cbfbtm1Itan
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal CD8-positive, alpha beta T cell morphology J:158962, J:125953
abnormal CD8-positive, alpha-beta T cell number J:125953
abnormal T cell differentiation J:125953
abnormal T-helper 1 cell differentiation J:125953
decreased CD8-positive, alpha-beta T cell number J:158962
increased double-positive T cell number J:158962
increased IgA level J:125953
increased IgE level J:125953
increased IgG1 level J:125953
increased immunoglobulin level J:125953
lung inflammation J:125953
Cbfbtm1Itan/Cbfbtm1Itan
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd)
abnormal CD4-positive T cell differentiation J:125953
abnormal CD8-positive, alpha-beta T cell differentiation J:125953
abnormal double-positive T cell morphology J:125953
abnormal T-helper 1 cell differentiation J:125953
decreased thymocyte number J:125953
Cbfbtm1Itan/Cbfbtm1Itan
Zbtb7btm2Litt/Zbtb7b+
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:141144
decreased CD4-positive, alpha-beta T cell number J:141144
Cbfbtm1Itan/Cbfbtm1Itan
Zbtb7btm2Litt/Zbtb7btm1.2Litt
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:141144
decreased CD4-positive, alpha-beta T cell number J:141144
Cbfbtm1Lhc/Cbfbtm1Lhc
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
abnormal myelopoiesis J:105040
abnormal spleen morphology J:105040
enlarged spleen J:105040
increased leukocyte cell number J:105040
Cbfbtm1Spe/Cbfbtm1Spe
Tg(Tek-GFP/Cbfb)1Spe/0

(either: (involves: 129S4/SvJae * BALB/c * CD-1) or (involves: 129S4/SvJae * C57BL/6 * CD-1))
abnormal myelopoiesis J:80670
abnormal splenic cell ratio J:80670
increased CD4-positive, alpha-beta T cell number J:80670
small thymus J:80670
spleen hypoplasia J:80670
Cbfbtm1Spe/Cbfbtm1Spe
Tg(Tek-GFP/Cbfb)2Spe/0

(either: (involves: 129S4/SvJae * BALB/c * CD-1 * Swiss Webster) or (involves: 129S4/SvJae * C57BL/6 * CD-1 * Swiss Webster))
abnormal myelopoiesis J:80670
abnormal splenic cell ratio J:80670
increased CD4-positive, alpha-beta T cell number J:80670
small thymus J:80670
spleen hypoplasia J:80670
Cbfbtm1Spe/Cbfbtm2.1Spe
(involves: 129S4/SvJae)
abnormal splenic cell ratio J:124224
abnormal T cell differentiation J:124224
abnormal thymus cell ratio J:124224
abnormal thymus morphology J:124224
decreased double-positive T cell number J:124224
increased CD4-positive, alpha-beta T cell number J:124224
thymus hypoplasia J:124224
Cbfbtm1Tok/Cbfbtm1Tok
Tg(Gata1-Cbfb)1Tok/0

(involves: 129P2/OlaHsd * C57BL/6J)
absent T cells J:80668
decreased lymphocyte cell number J:80668
small spleen J:80668
small thymus J:80668
Cbfbtm2.1Spe/Cbfbtm2.1Spe
(involves: 129S4/SvJae)
abnormal splenic cell ratio J:124224
abnormal T cell differentiation J:124224
abnormal thymus cell ratio J:124224
abnormal thymus morphology J:124224
decreased double-positive T cell number J:124224
increased CD4-positive, alpha-beta T cell number J:124224
thymus hypoplasia J:124224
Cbfbtm2Itan/Cbfbtm2Itan
(Not Specified)
abnormal lymph organ development J:168918
abnormal peripheral lymph node morphology J:168918
absent Peyer's patches J:168918
decreased Peyer's patch number J:168918
Cbfbtm5Ppl/Cbfb+
(Not Specified)
abnormal mononuclear cell differentiation J:193140
myeloid hyperplasia J:193140
Cbfbtm6Ppl/Cbfb+
(involves: 129S/SvEv * C57BL/6)
decreased B cell number J:252447
Cbltm1.1Hua/Cbltm1.1Hua
Lattm1Les/Lattm1Les

(involves: 129P2/OlaHsd)
abnormal thymus development J:91369
increased CD4-positive, alpha-beta T cell number J:91369
liver inflammation J:91369
lung inflammation J:91369
thymus hypoplasia J:91369
Cbltm1.1Hua/Cbltm1.1Hua
Lcp2tm1Gak/Lcp2tm1Gak

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
abnormal cytokine secretion J:91369
abnormal T cell differentiation J:91369
enlarged spleen J:91369
increased CD4-positive, alpha-beta T cell number J:91369
liver inflammation J:91369
lung inflammation J:91369
Cbltm1.1Hua/Cbltm1.1Hua
Lcp2tm1Gak/Lcp2tm1Gak
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ)
abnormal T cell differentiation J:91369
Cbltm1Ddlb/Cbltm1Ddlb
(involves: 129S1/Sv * C57BL/6J)
abnormal lymph node cell ratio J:76895
abnormal spleen morphology J:76895
abnormal splenic cell ratio J:76895
abnormal thymus cell ratio J:76895
enlarged lymph nodes J:76895
enlarged spleen J:76895
Cbltm1Ddlb/Cbltm1Ddlb
(involves: 129S1/Sv)
abnormal T cell physiology J:81965
enlarged spleen J:81965
increased spleen red pulp amount J:81965
spleen hyperplasia J:81965
Cbltm1Ddlb/Cbltm1Ddlb
(involves: 129S1/Sv * C57BL/6)
enlarged spleen J:103366
increased spleen red pulp amount J:103366
spleen hyperplasia J:103366
Cbltm1Ddlb/Cbltm2Wlan
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal double-negative T cell morphology J:103366
abnormal lymph node cell ratio J:103366
abnormal spleen morphology J:103366
abnormal splenic cell ratio J:103366
abnormal T cell activation J:103366
abnormal T cell differentiation J:103366
abnormal T cell physiology J:103366
abnormal thymus morphology J:103366
abnormal thymus size J:103366
decreased single-positive T cell number J:103366
enlarged spleen J:103366
increased spleen red pulp amount J:103366
spleen hyperplasia J:103366
thymus hypoplasia J:103366
Cbltm1Soga/Cbltm1Soga
(Not Specified)
enlarged spleen J:151543
Cbltm1Soga/Cbltm1Soga
Tg(Tec-BCR/ABL1)5Hhi/0

(involves: C57BL/6 * DBA/2)
enlarged lymph nodes J:151543
Cbltm1Wlan/Cbltm1Wlan
(involves: 129S1/Sv * C57BL/6)
abnormal T cell physiology J:81965
enlarged spleen J:81965
increased spleen red pulp amount J:81965
myeloid hyperplasia J:81965
spleen hyperplasia J:81965
Cbltm2Hua/Cbltm2Hua
Cblbtm1Hua/Cblbtm1Hua
Tg(Lck-cre)I57Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * ICR)
abnormal immune system physiology J:80427
abnormal T cell morphology J:80427
dermatitis J:80427
enlarged spleen J:80427
increased T cell proliferation J:80427
Cbltm2Wlan/Cbltm2Wlan
(involves: 129X1/SvJ * C57BL/6)
abnormal spleen morphology J:103366
abnormal thymus morphology J:103366
abnormal thymus size J:103366
enlarged spleen J:103366
increased spleen red pulp amount J:103366
spleen hyperplasia J:103366
thymus hypoplasia J:103366
Cblbtm1Hua/Cblbtm1Hua
(Not Specified)
increased T cell proliferation J:89761
Cblbtm1Hua/Cblbtm1Hua
(B6.129P2-Cblbtm1Hua)
increased interleukin-2 secretion J:94685
increased susceptibility to experimental autoimmune encephalomyelitis J:94685
increased T cell proliferation J:94685
Cblbtm1Hua/Cblbtm1Hua
Ubash3btm1Jni/Ubash3btm1Jni
Ubash3atm1Jni/Ubash3atm1Jni

(Not Specified)
increased susceptibility to experimental autoimmune encephalomyelitis J:89761
increased T cell proliferation J:89761
Cblbtm1Pngr/Cblbtm1Pngr
(involves: 129 * C57BL/6)
abnormal mast cell physiology J:126361
increased interleukin-6 secretion J:126361
increased tumor necrosis factor secretion J:126361
Cblbtm1Pngr/Cblbtm1Pngr
(B6.129P2-Cblbtm1Pngr)
increased T cell proliferation J:141390
Cblbtm1Pngr/Cblbtm1Pngr
Itktm1Litt/Itktm1Litt

(B6.129-Itktm1Litt Cblbtm1Pngr)
abnormal T cell morphology J:141390
abnormal T-helper 2 cell differentiation J:141390
decreased interleukin-2 secretion J:141390
decreased T cell number J:141390
immune system phenotype J:141390
Cblbtm1Pngr/Cblbtm1Pngr
Vav1tm1Tyb/Vav1tm1Tyb
Wastm1Sbs/Wastm1Sbs

(involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac)
abnormal T cell physiology J:79550
Cblbtm1Pngr/Cblbtm1Pngr
Wastm1Sbs/Wastm1Sbs

(Not Specified)
abnormal T cell physiology J:79550
Cblbtm1Wlan/Cblbtm1Wlan
(involves: 129X1/SvJ * C57BL/6)
abnormal mast cell physiology J:126361
increased interleukin-6 secretion J:126361
increased tumor necrosis factor secretion J:126361
Cbliftm1a(KOMP)Wtsi/Cbliftm1a(KOMP)Wtsi
(C57BL/6N-Cbliftm1a(KOMP)Wtsi)
increased CD4-positive, alpha-beta T cell number J:236022
increased susceptibility to bacterial infection J:236022
increased susceptibility to bacterial infection induced morbidity/mortality J:236022
increased T cell number J:236022
Cbstm1Unc/Cbstm1Unc
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal interleukin level J:101303
abnormal tumor necrosis factor level J:101303
absent uterine NK cells J:190486
decreased uterine NK cell number J:190486
liver inflammation J:101303
Cbstm1Unc/Cbstm1Unc
Tg(Mt1-CBS*S466L)EB86Waku/0

(involves: 129P2/OlaHsd * C3H * C57BL/6)
increased Ly6C high monocyte number J:168131
increased monocyte cell number J:168131
Cbx2tm1Cim/Cbx2tm1Cim
(involves: 129P2/OlaHsd * BALB/c)
arrested T cell differentiation J:38487
decreased splenocyte proliferation J:38487
Cbx3tm1Ics/Cbx3tm1Ics
(involves: 129S2/SvPas * C57BL/6)
immune system phenotype J:186702
Cbx4tm1.1Gxu/Cbx4tm1.2Gxu
Tg(Foxn1-cre)1Tbo/0

(involves: 129S2/SvPas * C57BL/6J)
abnormal lymphopoiesis J:194053
abnormal thymus development J:194053
abnormal thymus physiology J:194053
decreased double-positive T cell number J:194053
decreased T cell number J:194053
thymus atrophy J:194053
thymus hypoplasia J:194053
Cbx4tm1.2Gxu/Cbx4tm1.2Gxu
(involves: 129S2/SvPas * C57BL/6J)
abnormal thymus development J:194053
abnormal thymus physiology J:194053
thymus hypoplasia J:194053
Cbx5tm1.1Ics/Cbx5tm1.1Ics
(involves: 129S2/SvPas * C57BL/6)
abnormal T-helper 2 physiology J:186702
immune system phenotype J:186702
Cbx6tm1a(EUCOMM)Wtsi/Cbx6tm1a(EUCOMM)Wtsi
(C57BL/6N-Cbx6tm1a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Cby1tm1Ktkm/Cby1tm1Ktkm
(B6.129-Cby1tm1Ktkm)
increased susceptibility to bacterial infection J:147413
increased susceptibility to otitis media J:147413
sinus inflammation J:147413
Cc2d1atm1a(KOMP)Wtsi/Cc2d1atm1a(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
decreased interferon-beta secretion J:190401
decreased interleukin-6 secretion J:190401
Ccar2Gt(XN876)Byg/Ccar2Gt(XN876)Byg
(involves: 129P2/OlaHsd * C57BL/6)
decreased tumor necrosis factor secretion J:156677
Ccbe1tm1Lex/Ccbe1tm1Lex
(involves: 129S5/SvEvBrd)
abnormal lymphangiogenesis J:186594
absent lymphatic vessels J:186594
Ccbe1tm1Mlkn/Ccbe1tm1Mlkn
(either: B6.129-Ccbe1tm1Mlkn or (involves: 129 * C57BL/6))
abnormal macrophage physiology J:196696
absent lymphatic vessels J:196696
decreased macrophage cell number J:196696
Ccdc25em1(IMPC)Mbp/Ccdc25+
(C57BL/6N-Ccdc25em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Ccdc39b2b2025.1Clo/Ccdc39b2b2025.1Clo
(C57BL/6J-Ccdc39b2b2025.1Clo)
absent spleen J:175213
spleen hypoplasia J:175213
Ccdc40em1(IMPC)J/Ccdc40em1(IMPC)J
(C57BL/6NJ-Ccdc40em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ccdc86tm1Hfuj/Ccdc86+
(involves: C57BL/6NTac)
abnormal T cell morphology J:151722
decreased T cell apoptosis J:151722
Ccdc88bem1(IMPC)Tcp/Ccdc88bem1(IMPC)Tcp
(C57BL/6NCrl-Ccdc88bem1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
Ccdc88bm1Pgrs/Ccdc88bm1Pgrs
(involves: C57BL/6J * C57BL/10J)
decreased CD8-positive, alpha-beta T cell number J:230618
decreased interferon-gamma secretion J:230618
decreased susceptibility to parasitic infection J:230618
decreased susceptibility to parasitic infection induced morbidity/mortality J:230618
decreased T cell proliferation J:230618
decreased tumor necrosis factor secretion J:230618
immune system phenotype J:230618
Ccdc88bm1Pgrs/Ccdc88bm1Pgrs
(involves: 129S1/SvImJ * C57BL/6J * C57BL/10J)
decreased susceptibility to parasitic infection induced morbidity/mortality J:230618
Ccdc92tm1a(KOMP)Mbp/Ccdc92tm1a(KOMP)Mbp
(C57BL/6N-Ccdc92tm1a(KOMP)Mbp)
decreased circulating interleukin-1 beta level J:332421
decreased circulating interleukin-18 level J:332421
decreased inflammatory response J:332421
decreased macrophage cell number J:332421
Ccdc110em1(IMPC)Ccpcz/Ccdc110em1(IMPC)Ccpcz
(C57BL/6NCrl-Ccdc110em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Ccdc124tm1b(KOMP)Wtsi/Ccdc124tm1b(KOMP)Wtsi
(C57BL/6N-Ccdc124tm1b(KOMP)Wtsi/Nju)
small spleen J:211773
Ccdc127tm1b(EUCOMM)Wtsi/Ccdc127tm1b(EUCOMM)Wtsi
(C57BL/6N-Ccdc127tm1b(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Ccdc154ntl/Ccdc154ntl
(involves: 129S7/SvEvBrd * C57BL/6J)
enlarged spleen J:226596
Ccdc166em1(IMPC)J/Ccdc166em1(IMPC)J
(C57BL/6NJ-Ccdc166em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Ccdc171m1Anu/Ccdc171+
(C57BL/NCrlAnu-Ccdc171m1Anu/Anu)
decreased IgD level J:104190
decreased mature B cell number J:104190
increased IgM level J:104190
Ccdc171m1Anu/Ccdc171m1Anu
(C57BL/NCrlAnu-Ccdc171m1Anu/Anu)
decreased IgD level J:104190
decreased mature B cell number J:104190
increased IgM level J:104190
Ccdc198em1(IMPC)Ccpcz/Ccdc198em1(IMPC)Ccpcz
(C57BL/6NCrl-Ccdc198em1(IMPC)Ccpcz/Ph)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Cchcr1em1Aoka/Cchcr1+
(C57BL/6NJcl-Cchcr1em1Aoka)
immune system phenotype J:309941
Cchcr1em1Aoka/Cchcr1em1Aoka
(C57BL/6NJcl-Cchcr1em1Aoka)
immune system phenotype J:309941
Cckbrtm1Tom/Cckbrtm1Tom
(involves: 129S4/SvJae * C57BL/6J)
decreased susceptibility to endotoxin shock J:143853
Ccl1tm1Sman/Ccl1tm1Sman
(B6.129-Ccl1tm1Sman)
abnormal inflammatory response J:138942
abnormal regulatory T cell physiology J:138942
Ccl2tm1.1Pame/Ccl2tm1.1Pame
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:171379
Ccl2tm1.1Pame/Ccl2tm1.1Pame
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: C57BL/6 * DBA)
immune system phenotype J:171379
Ccl2tm1.1Pame/Ccl2tm1.1Pame
Tg(Nes-cre)1Kln/0

(involves: C57BL/6 * SJL)
abnormal leukocyte migration J:171379
increased susceptibility to bacterial infection J:171379
Ccl2tm1.1Pame/Ccl2tm1.1Pame
Tg(Tek-cre)12Flv/0

(involves: C3H * C57BL/6)
abnormal leukocyte migration J:171379
increased susceptibility to bacterial infection J:171379
Ccl2tm1.1Tyos/Ccl2tm1.1Tyos
(involves: 129S1/Sv * C57BL/6)
abnormal chemokine level J:151874
abnormal chemokine secretion J:151874
abnormal neutrophil physiology J:151874
impaired macrophage chemotaxis J:151874
Ccl2tm1.1Tyos/Ccl2tm1.1Tyos
(involves: 129S1/Sv)
abnormal dendritic cell chemotaxis J:199611
abnormal dendritic cell physiology J:199611
decreased dendritic cell number J:199611
Ccl2tm1Lex/Ccl2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
impaired macrophage chemotaxis J:191510
Ccl2tm1Rol/Ccl2+
Mpztm1Msch/Mpz+

(involves: 129S4/SvJae * 129S7/SvEvBrd)
abnormal macrophage derived foam cell morphology J:133028
decreased macrophage cell number J:133028
Ccl2tm1Rol/Ccl2+
Tg(PMP22)C61Clh/0

(involves: 129S4/SvJae * C57BL/6J * CBA/Ca)
increased macrophage cell number J:158350
Ccl2tm1Rol/Ccl2tm1Rol
(involves: 129S4/SvJae * 129X1/SvJ * C57BL/6)
abnormal monocyte morphology J:45920
decreased interferon-gamma secretion J:45920
decreased interleukin-4 secretion J:45920
decreased interleukin-5 secretion J:45920
decreased susceptibility to type IV hypersensitivity reaction J:45920
impaired macrophage chemotaxis J:45920
Ccl2tm1Rol/Ccl2tm1Rol
(involves: 129S4/SvJae * C57BL/6)
abnormal macrophage chemotaxis J:116878
abnormal T cell physiology J:116878
decreased interferon-gamma secretion J:116878
decreased interleukin-1 beta secretion J:116878
decreased interleukin-12b secretion J:116878
decreased susceptibility to induced colitis J:116878
impaired macrophage chemotaxis J:108533
Ccl2tm1Rol/Ccl2tm1Rol
(involves: 129S4/SvJae)
abnormal macrophage physiology J:155025
abnormal monocyte morphology J:121281
decreased inflammatory response J:155025
decreased lymphocyte cell number J:147697
decreased macrophage cell number J:147697
impaired macrophage chemotaxis J:147697
increased circulating interferon-gamma level J:155025
increased circulating interleukin-10 level J:155025
increased circulating tumor necrosis factor level J:155025
increased susceptibility to infection induced morbidity/mortality J:155025
increased susceptibility to parasitic infection J:155025
Ccl2tm1Rol/Ccl2tm1Rol
(B6.129S4-Ccl2tm1Rol)
abnormal chemokine level J:151874, J:118606
abnormal chemokine secretion J:151874
abnormal cytokine secretion J:68145
abnormal macrophage chemotaxis J:109290
abnormal neutrophil physiology J:151874
decreased interferon-gamma secretion J:68145
decreased leukocyte cell number J:68145
decreased macrophage cell number J:147328
decreased susceptibility to experimental autoimmune encephalomyelitis J:68145
impaired macrophage chemotaxis J:151874, J:68145, J:118606
increased CD4-positive, alpha-beta T cell number J:68145
increased IgG1 level J:68145
increased IgG level J:147328
increased interleukin-10 secretion J:68145
increased neutrophil cell number J:118606
increased osteoclast cell number J:109290
Ccl2tm1Rol/Ccl2tm1Rol
(SJL.129S4-Ccl2tm1Rol)
decreased susceptibility to experimental autoimmune encephalomyelitis J:68145
Ccl2tm1Rol/Ccl2tm1Rol
((129S4/SvJae x C57BL/6)F1)
decreased macrophage cell number J:119615
Ccl2tm1Rol/Ccl2tm1Rol
(B6.129S4-Ccl2tm1Rol/J)
abnormal microglial cell physiology J:141739
Ccl2tm1Rol/Ccl2tm1Rol
Cx3cr1tm1Litt/Cx3cr1tm1Litt

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J)
abnormal macrophage physiology J:200877
abnormal microglial cell morphology J:200877
increased microglial cell activation J:200877
Ccl2tm1Rol/Ccl2tm1Rol
Mpztm1Msch/Mpz+

(involves: 129S4/SvJae * 129S7/SvEvBrd)
abnormal cytokine level J:133028
decreased macrophage cell number J:133028
increased macrophage cell number J:133028
Ccl2tm1Rol/Ccl2tm1Rol
Tg(Ccr2-GFP)8Pam/0

(involves: 129S4/SvJae * C57BL/6J)
abnormal leukocyte migration J:171379
Ccl2tm1Rol/Ccl2tm1Rol
Tg(PMP22)C61Clh/0

(involves: 129S4/SvJae * C57BL/6J * CBA/Ca)
increased macrophage cell number J:158350
Ccl2tm1Tyos/Ccl2tm1Tyos
(involves: 129S1/Sv * C57BL/6)
abnormal chemokine level J:151874
abnormal chemokine secretion J:151874
Ccl3tm1Unc/Ccl3tm1Unc
(involves: 129P2/OlaHsd)
abnormal susceptibility to Orthomyxoviridae infection J:107677
cecum inflammation J:107677
decreased susceptibility to bacterial infection J:107677
decreased susceptibility to Orthomyxoviridae infection J:107677
decreased susceptibility to Picornaviridae infection J:28704
Ccl3tm1Unc/Ccl3tm1Unc
(B6.129P2-Ccl3tm1Unc/J)
decreased neutrophil cell number J:94599
decreased susceptibility to type III hypersensitivity reaction J:94599
Ccl3tm1Unc/Ccl3tm1Unc
(involves: 129P2/OlaHsd * C57BL/6)
decreased microglial cell activation J:153059
Ccl3tm1Unc/Ccl3tm1Unc
Hexbtm1Rlp/Hexbtm1Rlp

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal tumor necrosis factor level J:90687
CNS inflammation J:90687
Ccl4em1Narl/Ccl4em1Narl
(C57BL/6JNarl-Ccl4em1Narl)
decreased inflammatory response J:346348
decreased susceptibility to autoimmune diabetes J:346348
Ccl5tm1Hso/Ccl5tm1Hso
(involves: 129P2/OlaHsd * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:75842
decreased interferon-gamma secretion J:75842
decreased interleukin-2 secretion J:75842
decreased susceptibility to type IV hypersensitivity reaction J:75842
decreased T cell proliferation J:75842
Ccl7tm1Ifc/Ccl7tm1Ifc
(involves: 129S4/SvJae)
abnormal monocyte morphology J:121281
Ccl11tm1Mer/Ccl11tm1Mer
(involves: 129S6/SvEvTac * NIH Black Swiss)
decreased eosinophil cell number J:38945
impaired eosinophil recruitment J:38945
Ccl11tm1Mer/Ccl11tm1Mer
(129S.129S6-Ccl11tm1Mer)
decreased eosinophil cell number J:102034
Ccl11tm1Mer/Ccl11tm1Mer
Ccl24tm1Mer/Ccl24tm1Mer

(129S.129S6(Cg)-Ccl24tm1Mer Ccl11tm1Mer)
abnormal immune system physiology J:102034
abnormal inflammatory response J:102034
Ccl11tm1Mer/Ccl11tm1Mer
Ccl24tm1Mer/Ccl24tm1Mer

(involves: 129S6/SvEvTac)
decreased eosinophil cell number J:115273
Ccl12tm1.1Ifc/Ccl12tm1.1Ifc
(involves: 129S4/SvJae)
immune system phenotype J:121281
Ccl12tm1Ifc/Ccl12tm1Ifc
(involves: 129S4/SvJae)
immune system phenotype J:121281
Ccl17em1(IMPC)H/Ccl17em1(IMPC)H
(C57BL/6N-Ccl17em1(IMPC)H/H)
increased spleen weight J:211773
Ccl17tm1.1Ifo/Ccl17tm1.1Ifo
(involves: 129P2/OlaHsd * C57BL/6)
decreased susceptibility to type IV hypersensitivity reaction J:159098
increased length of allograft survival J:159098
Ccl17tm2.1(cre)Ifo/Ccl17+
Hif1atm3Rsjo/Hif1atm3Rsjo

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal dendritic cell number J:187773
abnormal interleukin-1 beta secretion J:187773
abnormal leukocyte migration J:187773
abnormal tumor necrosis factor secretion J:187773
immune system phenotype J:187773
Ccl19tm1Cys/Ccl19tm1Cys
(B6.129X1-Ccl19tm1Cys)
abnormal immune system morphology J:126345
decreased T cell number J:126345
Ccl19tm1Cys/Ccl19tm1Cys
(involves: 129X1/SvJ)
immune system phenotype J:244640
Ccl21atm1Yout/Ccl21atm1Yout
(involves: C57BL/6NCrlj * CBA/JNCrlj)
abnormal negative T cell selection J:244640
abnormal spleen morphology J:244640
decreased alpha-beta T cell number J:244640
decreased B cell number J:244640
decreased thymocyte number J:244640
immune system phenotype J:244640
lacrimal gland inflammation J:244640
small thymus medulla J:244640
Ccl22tm1(KOMP)Vlcg/Ccl22tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal dendritic cell physiology J:236051
Ccl24tm1Mer/Ccl24tm1Mer
(129S.129S6-Ccl24tm1Mer)
abnormal immune system physiology J:98708, J:102034
Ccl24tm1Mer/Ccl24tm1Mer
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal immune system physiology J:98708
Ccl25em1(IMPC)H/Ccl25em1(IMPC)H
(C57BL/6N-Ccl25em1(IMPC)H/H)
enlarged spleen J:211773
increased spleen weight J:211773
Ccl25tm1.1Mal/Ccl25tm1.1Mal
(B6.129S2-Ccl25tm1.1Mal)
abnormal gamma-delta T cell number J:136944
abnormal mesenteric lymph node morphology J:136944
abnormal T cell subpopulation ratio J:136944
decreased gamma-delta intraepithelial T cell number J:136944
Ccl25tm1.1Mal/Ccl25tm1.1Mal
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6)
abnormal alpha-beta intraepithelial T cell morphology J:136667
abnormal T cell subpopulation ratio J:136667
decreased gamma-delta intraepithelial T cell number J:136667
intestinal inflammation J:136667
Ccl28em1(IMPC)Ccpcz/Ccl28em1(IMPC)Ccpcz
(C57BL/6NCrl-Ccl28em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Ccl28tm1Takna/Ccl28tm1Takna
(C57BL/6J-Ccl28tm1Takna)
abnormal immune system cell morphology J:256896
decreased IgA level J:256896
increased IgG level J:256896
increased susceptibility to induced colitis J:256896
Ccm2tm1Kwhi/Ccm2tm1.1Kwhi
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?

(involves: C57BL/6 * CBA)
CNS inflammation J:173947
Ccm2tm2.1Sbn/Ccm2tm2.1Sbn
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
microgliosis J:174085
Ccn3em1(IMPC)Mbp/Ccn3em1(IMPC)Mbp
(C57BL/6N-Ccn3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Ccn3tm1.1Ecan/Ccn3tm1.1Ecan
(B6.Cg-Ccn3tm1.1Ecan)
abnormal osteoclast differentiation J:158478
abnormal osteoclast physiology J:158478
Ccna1tm1Djw/Ccna1tm1Djw
Ccna2tm1.1Pisc/Ccna2tm1.1Pisc
Tg(Mx1-cre)1Cgn/0

(involves: 129S7/SvEvBrd * C57BL/6 * CBA)
decreased leukocyte cell number J:155178
Ccnb1ip1em1(IMPC)Tcp/Ccnb1ip1em1(IMPC)Tcp
(C57BL/6NCrl-Ccnb1ip1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Ccnb2tm1Thnt/Ccnb2tm1Thnt
(involves: 129P2/OlaHsd * C57BL/6)
increased double-negative T cell number J:47430
small thymus J:47430
Ccnd1tm1Dsn/Ccnd1tm1Dsn
Ccnd2tm1Wbg/Ccnd2tm1Wbg
Ccnd3tm1Pisc/Ccnd3tm1Pisc

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal lymphopoiesis J:92563
Ccnd1tm1Dsn/Ccnd1tm1Dsn
Cdkn1btm1Mlf/Cdkn1btm1Mlf

(involves: 129 * C57BL/6)
enlarged spleen J:66707
enlarged thymus J:66707
thymus hyperplasia J:66707
Ccnd3tm1.1(Ccnd2)Iaai/Ccnd3tm1.1(Ccnd2)Iaai
(involves: 129S6/SvEvTac)
decreased B cell proliferation J:192031
decreased double-positive T cell number J:192031
decreased pre-B cell number J:192031
decreased T cell proliferation J:192031
small thymus J:192031
thymus hypoplasia J:192031
Ccnd3tm1Pisc/Ccnd3tm1Pisc
(Not Specified)
decreased B cell proliferation J:192031
decreased double-positive T cell number J:88120, J:192031
decreased lymphocyte cell number J:88120
decreased pre-B cell number J:192031
decreased T cell proliferation J:88120, J:192031
increased double-negative T cell number J:88120
small thymus J:192031
thymus hypoplasia J:88120, J:192031
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Cdkn1btm1Mlf/Cdkn1btm1Mlf

(involves: 129S4/SvJaeSor)
decreased double-positive T cell number J:192031
decreased T cell proliferation J:192031
thymus hypoplasia J:192031
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Cdkn1btm1Mlf/Cdkn1btm1Mlf
Rb1tm2Brn/Rb1tm2Brn
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJaeSor * C57BL/6 * CBA)
immune system phenotype J:192031
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv)
increased T cell proliferation J:88120
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Rb1tm2Brn/Rb1tm2Brn
Tg(Mx1-cre)1Cgn/0

(involves: 129 * C57BL/6 * CBA)
decreased double-positive T cell number J:192031
decreased T cell proliferation J:192031
thymus hypoplasia J:192031
Ccnd3tm2.1Pisc/Ccnd3tm2.1Pisc
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
decreased double-positive T cell number J:192032
decreased leukocyte cell number J:192032
small thymus J:192032
Ccne1tm1Clur/Ccne1tm1Clur
(involves: 129S4/SvJae)
abnormal myeloid leukocyte morphology J:136692
abnormal spleen red pulp morphology J:136692
enlarged spleen J:136692
immune system phenotype J:136692
spleen hyperplasia J:136692
Ccne1tm1Jro/Ccne1tm1Jro
(either: 129-Ccne1tm1Jro or B6.129-Ccne1tm1Jro)
increased spleen weight J:99695
increased splenocyte proliferation J:99695
Ccne1tm1Pisc/Ccne1tm1Pisc
Ccne2tm1Pisc/Ccne2tm1Pisc

(involves: 129S2/SvPas)
abnormal thrombopoiesis J:85224
Ccnoem1(IMPC)Mbp/Ccno+
(C57BL/6N-Ccnoem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Ccnotm1b(EUCOMM)Wtsi/Ccnotm1b(EUCOMM)Wtsi
(involves: C57BL/6 * C57BL/6N * CBA)
immune system phenotype J:220709
Ccnt1em1(IMPC)J/Ccnt1+
(C57BL/6NJ-Ccnt1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ccnt1em1(IMPC)J/Ccnt1em1(IMPC)J
(C57BL/6NJ-Ccnt1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ccnt1Gt(RRR115)Byg/Ccnt1Gt(RRR115)Byg
(involves: 129P2/OlaHsd)
abnormal thymus physiology J:130071
autoimmune response J:130071
immune system phenotype J:130071
lacrimal gland inflammation J:130071
salivary gland inflammation J:130071
Ccpg1tm1a(EUCOMM)Hmgu/Ccpg1tm1a(EUCOMM)Hmgu
(C57BL/6N-Ccpg1tm1a(EUCOMM)Hmgu)
pancreas inflammation J:256708
Ccr1tm1Cge/Ccr1tm1Cge
(involves: 129S4/SvJae)
decreased tumor necrosis factor secretion J:43569
glomerulonephritis J:115119
immune system phenotype J:115119
impaired neutrophil recruitment J:43569
increased IgG2a level J:115119
increased interferon-gamma secretion J:115119
increased susceptibility to type IV hypersensitivity reaction J:115119
increased tumor necrosis factor secretion J:115119
lung inflammation J:43569
Ccr1tm1Cge/Ccr1tm1Cge
(involves: 129S4/SvJae * C57BL/6)
cecum inflammation J:107677
decreased susceptibility to bacterial infection J:107677
decreased susceptibility to experimental autoimmune encephalomyelitis J:63952
immune system phenotype J:63952
increased length of allograft survival J:59235
Ccr1tm1Cge/Ccr1tm1Cge
(involves: 129S4/SvJae * BALB/c)
abnormal chemokine secretion J:169909
abnormal circulating chemokine level J:169909
abnormal macrophage physiology J:169909
decreased circulating interferon-gamma level J:169909
decreased interleukin-10 secretion J:169909
decreased susceptibility to bacterial infection J:169909
decreased susceptibility to bacterial infection induced morbidity/mortality J:169909
decreased tumor necrosis factor secretion J:169909
increased interleukin-12 secretion J:169909
increased macrophage nitric oxide production J:169909
increased tumor necrosis factor secretion J:169909
Ccr1tm1Cge/Ccr1tm1Cge
(C.129S4-Ccr1tm1Cge)
decreased CD4-positive, alpha-beta T cell number J:95242
decreased CD8-positive, alpha-beta T cell number J:95242
decreased interleukin-13 secretion J:95242
decreased susceptibility to Riboviria infection J:95242
Ccr1tm1Gao/Ccr1tm1Gao
(involves: 129S4/SvJae * C57BL/6)
abnormal neutrophil physiology J:41324
granulomatous inflammation J:41324
immune system phenotype J:41324
increased susceptibility to fungal infection J:41324
increased susceptibility to parasitic infection J:41324
Ccr1tm1Gao/Ccr1tm1Gao
(involves: C57BL/6)
decreased mast cell number J:94599
decreased susceptibility to type III hypersensitivity reaction J:94599
Ccr1tm1Gao/Ccr1tm1Gao
(B6.129S4-Ccr1tm1Gao)
abnormal cellular extravasation J:104744
abnormal leukocyte adhesion J:104744
bronchiolitis J:162707
increased susceptibility to Coronaviridae infection J:162707
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:162707
Ccr1tm1Gao/Ccr1tm1Gao
(involves: 129S4/SvJae)
abnormal Kupffer cell morphology J:152548
Ccr1l1em1Semp/Ccr1l1em1Semp
(C57BL/6NTac-Ccr1l1em1Semp)
immune system phenotype J:304824
Ccr1l1em2Semp/Ccr1l1em2Semp
(C57BL/6NTac-Ccr1l1em2Semp)
immune system phenotype J:304824
Ccr2em1(IMPC)H/Ccr2em1(IMPC)H
(C57BL/6N-Ccr2em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
increased eosinophil cell number J:211773
Ccr2tm1.1(CCR2)Rodb/Ccr2tm1.1(CCR2)Rodb
(involves: C57BL/6)
abnormal macrophage morphology J:203000
immune system phenotype J:203000
Ccr2tm1.1Dnc/Ccr2tm1.1Dnc
(Not Specified)
abnormal dendritic cell chemotaxis J:223508
decreased CD11b-high dendritic cell number J:223508
increased CD11b-high dendritic cell number J:223508
increased dendritic cell number J:223508
Ccr2tm1.1Mpa/Ccr2tm1.1Mpa
(involves: BALB/cJ * C57BL/6)
decreased macrophage cell number J:189044
decreased monocyte cell number J:189044
Ccr2tm1Blck/Ccr2tm1Blck
(B6.129P2-Ccr2tm1Blck)
abnormal cellular extravasation J:104744
abnormal leukocyte adhesion J:104744
Ccr2tm1Blck/Ccr2tm1Blck
Faslpr/Faslpr

(MRL.Cg-Ccr2tm1Blck Faslpr)
abnormal immune system organ morphology J:113343
abnormal interferon level J:113343
abnormal lymphocyte cell number J:113343
abnormal tumor necrosis factor level J:113343
enlarged lymph nodes J:113343
enlarged spleen J:113343
glomerulonephritis J:113343
kidney inflammation J:113343
Ccr2tm1Brv/Ccr2tm1Brv
(involves: 129S1/Sv * ICR)
abnormal spleen morphology J:111517
enlarged spleen J:111517
impaired macrophage chemotaxis J:111517
increased eosinophil cell number J:111517
increased susceptibility to bacterial infection J:111517
liver inflammation J:111517
Ccr2tm1Ifc/Ccr2+
(involves: 129S4/SvJae * C57BL/6)
impaired macrophage chemotaxis J:121703
Ccr2tm1Ifc/Ccr2tm1Ifc
(B6.129S4-Ccr2tm1Ifc/J)
abnormal leukocyte migration J:106738
abnormal leukocyte physiology J:122119
abnormal microglial cell physiology J:106738
abnormal osteoclast cell number J:149360
abnormal osteoclast differentiation J:149360
abnormal osteoclast physiology J:149360
decreased acute inflammation J:106738
decreased interferon-gamma secretion J:106738
decreased osteoclast cell number J:149360
increased susceptibility to Coronaviridae infection J:106738
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:106738
Ccr2tm1Ifc/Ccr2tm1Ifc
(involves: 129S4/SvJae)
abnormal monocyte morphology J:121281
Ccr2tm1Ifc/Ccr2tm1Ifc
(involves: 129S4/SvJae * C57BL/6)
abnormal immune serum protein physiology J:118971
abnormal Langerhans cell physiology J:112594
abnormal macrophage chemotaxis J:44345
abnormal microglial cell physiology J:121703
decreased inflammatory response J:44345
decreased interferon-gamma secretion J:75838, J:44345
decreased interleukin-2 secretion J:44345
decreased interleukin-6 secretion J:75838
decreased splenocyte proliferation J:75838
decreased susceptibility to experimental autoimmune encephalomyelitis J:75838
decreased susceptibility to type I hypersensitivity reaction J:118971
decreased T cell proliferation J:75838
impaired macrophage chemotaxis J:81363, J:44345, J:121703
increased interferon-gamma secretion J:61542
increased tumor necrosis factor secretion J:61542
Ccr2tm1Ifc/Ccr2tm1Ifc
(B6.129S4-Ccr2tm1Ifc)
decreased susceptibility to induced colitis J:161138
immune system phenotype J:154558
impaired leukocyte tethering or rolling J:154558
Ccr2tm1Ifc/Ccr2tm1Ifc
Tg(APPSWE)2576Kha/0

(involves: 129S4/SvJae * C57BL/6 * SJL)
abnormal microglial cell physiology J:121703
Ccr2tm1Mae/Ccr2tm1Mae
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal cytokine secretion J:110814
decreased CD4-positive, alpha-beta T cell number J:110814
decreased inflammatory response J:110814
increased B cell number J:110814
increased CD8-positive, alpha-beta T cell number J:110814
increased susceptibility to induced colitis J:110814
Ccr2tm1Mae/Ccr2tm1Mae
(B6.129P2-Ccr2tm1Mae)
bronchiolitis J:162707
decreased macrophage cell number J:147328
increased IgG level J:147328
increased susceptibility to Coronaviridae infection J:162707
Ccr2tm1Mae/Ccr2tm1Mae
(involves: 129P2/OlaHsd)
abnormal chemokine secretion J:151874
abnormal leukocyte migration J:171379
impaired macrophage chemotaxis J:191510, J:151874
Ccr2tm1Mae/Ccr2tm1Mae
(involves: 129P2/OlaHsd * BALB/c)
abnormal leukocyte physiology J:162714
decreased neutrophil cell number J:162714
impaired macrophage chemotaxis J:162714
Ccr2tm1Mpa/Ccr2tm1Mpa
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased macrophage cell number J:189044
Ccr2tm2.1Ifc/Ccr2tm2.1Ifc
Cx3cr1tm1Litt/Cx3cr1+

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal leukocyte physiology J:166664
decreased susceptibility to experimental autoimmune encephalomyelitis J:166664
Ccr2tm2.1Ifc/Ccr2tm2.1Ifc
Cx3cr1tm1Litt/Cx3cr1tm1Litt

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal leukocyte physiology J:166664
decreased susceptibility to experimental autoimmune encephalomyelitis J:166664
Ccr3em1(IMPC)Ccpcz/Ccr3em1(IMPC)Ccpcz
(C57BL/6NCrl-Ccr3em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Ccr3tm1Cge/Ccr3tm1Cge
(involves: 129S4/SvJae * BALB/c)
abnormal eosinophil cell number J:74509
abnormal eosinophil physiology J:74509, J:75347
abnormal mast cell physiology J:74509
decreased circulating interleukin-4 level J:115273
decreased eosinophil cell number J:115273, J:74509, J:75347
decreased monocyte cell number J:115273
impaired eosinophil chemotaxis J:74509
impaired eosinophil recruitment J:74509, J:75347
increased eosinophil cell number J:74509
increased mast cell degranulation J:74509
Ccr4tm1Pwr/Ccr4tm1Pwr
(involves: 129P2/OlaHsd * C57BL/6)
abnormal chemokine secretion J:70088
abnormal cytokine secretion J:120221
abnormal splenocyte physiology J:70088
decreased eosinophil cell number J:120221
decreased IgE level J:120221
decreased interleukin-1 beta secretion J:70088
decreased interleukin-4 secretion J:120221
decreased interleukin-5 secretion J:120221
decreased interleukin-10 secretion J:120221
decreased interleukin-13 secretion J:120221
decreased lymphocyte cell number J:70088
decreased macrophage cell number J:70088
decreased susceptibility to endotoxin shock J:70088
decreased susceptibility to fungal infection J:120221
decreased tumor necrosis factor secretion J:70088
immune system phenotype J:70088
increased IgE level J:120221
increased IgG1 level J:120221
increased interferon-gamma secretion J:120221
increased interleukin-4 secretion J:120221
increased interleukin-5 secretion J:120221
increased interleukin-10 secretion J:120221
increased macrophage cell number J:120221
increased neutrophil cell number J:120221
increased tumor necrosis factor secretion J:120221
Ccr4tm1Pwr/Ccr4tm1Pwr
(B6.129P2-Ccr4tm1Pwr)
increased CD8-positive, alpha-beta T cell number J:95239
increased length of allograft survival J:95239
increased NK T cell number J:95239
Ccr5tm1Blck/Ccr5tm1Blck
(B6.129P2-Ccr5tm1Blck)
abnormal cellular extravasation J:104744
abnormal leukocyte adhesion J:104744
increased length of allograft survival J:105072
Ccr5tm1Brv/Ccr5tm1Brv
(either: (involves: 129S1/Sv * ICR) or (involves: 129S1/Sv * 129X1/SvJ * ICR))
abnormal cytokine secretion J:46941
decreased interleukin-1 beta secretion J:46941
decreased interleukin-6 secretion J:46941
decreased susceptibility to endotoxin shock J:46941
increased IgG1 level J:46941
increased interferon-gamma secretion J:46941
increased interleukin-4 secretion J:46941
increased susceptibility to bacterial infection J:46941
increased susceptibility to type IV hypersensitivity reaction J:46941
Ccr5tm1Kuz/Ccr5tm1Kuz
(involves: 129P2/OlaHsd * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:110814
abnormal CD8-positive, alpha beta T cell morphology J:110814
abnormal cytokine level J:110814
abnormal Kupffer cell morphology J:152548
abnormal NK T cell physiology J:100869
decreased microglial cell activation J:153059
decreased NK cell number J:135308
decreased susceptibility to induced colitis J:110814
decreased susceptibility to Retroviridae infection J:132342
impaired macrophage chemotaxis J:153059, J:84243, J:64293
increased NK T cell number J:110814
increased susceptibility to fungal infection J:64293
Ccr5tm1Kuz/Ccr5tm1Kuz
(B6.129P2-Ccr5tm1Kuz)
bronchiolitis J:162707
increased susceptibility to Coronaviridae infection J:162707
Ccr5tm1Kuz/Ccr5tm1Kuz
(involves: 129P2/OlaHsd)
decreased inflammatory response J:227458
Ccr5tm1Kuz/Ccr5tm1Kuz
Cxcr4tm1Qma/Cxcr4tm1Qma

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6)
decreased susceptibility to Retroviridae infection J:132342
Ccr5tm1Sush/Ccr5tm1Sush
(B6.129P2-Ccr5tm1Sush)
abnormal leukocyte physiology J:94937
decreased T cell proliferation J:94937
Ccr6tm1(EGFP)Irw/Ccr6tm1(EGFP)Irw
(involves: 129S6/SvEvTac * C57BL/6)
abnormal alpha-beta intraepithelial T cell morphology J:85086
abnormal B cell physiology J:120122
abnormal CD4-positive, alpha-beta intraepithelial T cell morphology J:85086
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:85086
abnormal follicular dendritic cell physiology J:113363
abnormal gut-associated lymphoid tissue morphology J:113363, J:120122
abnormal Peyer's patch morphology J:120122
abnormal T cell physiology J:85086
decreased B cell number J:120122
decreased Peyer's patch number J:120122
increased T cell proliferation J:85086
Ccr6tm1(EGFP)Irw/Ccr6tm1(EGFP)Irw
(B6.129S6-Ccr6tm1(EGFP)Irw)
decreased interleukin-4 secretion J:132012
decreased interleukin-12 secretion J:132012
decreased susceptibility to bacterial infection J:132012
decreased tumor necrosis factor secretion J:132012
increased interferon-gamma secretion J:132012
Ccr6tm1.1(KOMP)Vlcg/Ccr6tm1.1(KOMP)Vlcg
(C57BL/6N-Ccr6tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
Ccr6tm1.1Jmf/Ccr6tm1.1Jmf
(B6.129-Ccr6tm1.1Jmf)
abnormal CD4-positive, alpha-beta T cell physiology J:152716
abnormal dendritic cell physiology J:152716
abnormal interleukin secretion J:152716
decreased inflammatory response J:152716
Ccr6tm1Gma/Ccr6tm1Gma
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:68191
abnormal myeloid dendritic cell morphology J:68191
abnormal Peyer's patch follicle morphology J:68191
abnormal Peyer's patch morphology J:68191
decreased inflammatory response J:68191
decreased leukocyte cell number J:68191
increased leukocyte cell number J:68191
Ccr6tm1Gma/Ccr6tm1Gma
Tg(Rorc-EGFP)1Ebe/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal effector T cell morphology J:137020
Ccr6tm1Lira/Ccr6tm1Lira
(involves: 129)
abnormal follicular dendritic cell antigen presentation J:113363
abnormal Peyer's patch T cell area morphology J:113363
abnormal T cell physiology J:123150
Ccr6tm1Lira/Ccr6tm1Lira
(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:148286
abnormal CD4-positive, alpha-beta T cell physiology J:148286
abnormal gut-associated lymphoid tissue morphology J:76461
abnormal intraepithelial T cell number J:76461
abnormal lymphocyte morphology J:148286
abnormal macrophage physiology J:124358
abnormal myeloid dendritic cell morphology J:124358
abnormal peritoneal macrophage morphology J:124358
abnormal Peyer's patch germinal center morphology J:76461
abnormal Peyer's patch morphology J:76461
decreased B cell number J:148286
decreased CD4-positive, alpha-beta T cell number J:148286
decreased CD8-positive, alpha-beta T cell number J:148286
decreased IgA level J:76461
decreased IgG3 level J:76461
decreased inflammatory response J:124358
decreased interleukin-10 secretion J:124358
decreased interleukin-12 secretion J:124358
decreased macrophage cytokine production J:124358
decreased macrophage nitric oxide production J:124358
decreased susceptibility to experimental autoimmune encephalomyelitis J:148286
decreased tumor necrosis factor secretion J:124358
increased activated T cell number J:76461
increased B-1 B cell number J:124358
increased double-positive T cell number J:76461
increased IgM level J:76461
increased susceptibility to Riboviria infection J:76461
increased T cell number J:76461
Ccr6tm1Lira/Ccr6tm1Lira
(B6.129-Ccr6tm1Lira)
decreased IgE level J:71096
decreased interleukin-5 secretion J:71096
decreased susceptibility to type I hypersensitivity reaction J:71096
impaired eosinophil recruitment J:71096
Ccr7m1Btlr/Ccr7+
(C57BL/6J-Ccr7m1Btlr)
decreased macrophage cell number J:221477
Ccr7m1Btlr/Ccr7m1Btlr
(C57BL/6J-Ccr7m1Btlr)
decreased macrophage cell number J:221477
increased single-positive T cell number J:221477
Ccr7tm1Dgen/Ccr7tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6)
chronic inflammation J:101679
Ccr7tm1Rfor/Ccr7tm1Rfor
(involves: 129P2/OlaHsd * BALB/c)
abnormal B cell activation J:57976
abnormal B cell physiology J:57976
abnormal class switch recombination J:57976
abnormal dendritic cell physiology J:57976
abnormal humoral immune response J:57976
abnormal leukocyte migration J:57976
abnormal lymph node cortex morphology J:57976
abnormal lymph node germinal center morphology J:57976
abnormal lymph node T cell domain morphology J:57976
abnormal Peyer's patch T cell area morphology J:57976
abnormal spleen marginal sinus morphology J:57976
abnormal spleen periarteriolar lymphoid sheath morphology J:57976
abnormal spleen red pulp morphology J:57976
abnormal T cell physiology J:57976
decreased CD4-positive, alpha-beta T cell number J:57976
decreased dendritic cell number J:57976
decreased IgG3 level J:57976
decreased susceptibility to type IV hypersensitivity reaction J:57976
decreased T cell number J:57976
enlarged spleen J:57976
increased CD4-positive, alpha-beta T cell number J:57976
increased IgE level J:57976
increased IgG1 level J:57976
increased IgG2a level J:57976
increased T cell number J:57976
small lymph nodes J:57976
small Peyer's patches J:57976
Ccr7tm1Rfor/Ccr7tm1Rfor
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal dendritic cell physiology J:134784
Ccr7tm1Rfor/Ccr7tm1Rfor
(B6.129P2-Ccr7tm1Rfor)
abnormal dendritic cell physiology J:183989
abnormal leukocyte migration J:93960, J:110910
abnormal thymus cortex morphology J:93960
immune system phenotype J:93960
increased inflammatory response J:110910
increased susceptibility to autoimmune disorder J:110910
lacrimal gland inflammation J:110910
parotid gland inflammation J:110910
salivary gland inflammation J:110910
small thymus medulla J:93960
submandibular gland inflammation J:110910
Ccr7tm1Rfor/Ccr7tm1Rfor
(B6.129P2(C)-Ccr7tm1Rfor/J)
decreased susceptibility to bacterial infection J:210086
Ccr7tm1Rfor/Ccr7tm1Rfor
(involves: 129P2/OlaHsd)
abnormal dendritic cell chemotaxis J:223508
decreased CD11b-high dendritic cell number J:223508
decreased CD103-positive CD11b-low dendritic cell number J:223508
Ccr7tm1Rfor/Ccr7tm1Rfor
Tg(DO11.10)10Dlo/?

(involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6)
abnormal leukocyte migration J:123482
abnormal regulatory T cell physiology J:123482
Ccr8tm1Lira/Ccr8tm1Lira
(involves: 129S/SvEv * C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:118417
Ccr9tm1.1Mal/Ccr9tm1.1Mal
(involves: 129S2/SvPas * C57BL/6)
abnormal leukocyte cell number J:72386
abnormal T cell differentiation J:72386
decreased double-positive T cell number J:72386
decreased pro-B cell number J:72386
decreased T cell number J:72386
increased T cell number J:72386
Ccr9tm1.1Mal/Ccr9tm1.1Mal
(involves: 129S2/SvPas)
abnormal gamma-delta T cell number J:136944
abnormal mesenteric lymph node morphology J:136944
abnormal T cell subpopulation ratio J:136944
decreased gamma-delta intraepithelial T cell number J:136944
Ccr9tm1.1Mal/Ccr9tm1.1Mal
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6)
abnormal alpha-beta intraepithelial T cell morphology J:136667
abnormal T cell subpopulation ratio J:136667
decreased gamma-delta intraepithelial T cell number J:136667
intestinal inflammation J:136667
Ccr9tm1Ccb/Ccr9tm1Ccb
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal T cell differentiation J:94596
decreased thymocyte number J:94596
Ccr9tm1Lov/Ccr9tm1Lov
(involves: 129)
abnormal gamma-delta intraepithelial T cell morphology J:110846
decreased CD8-positive, gamma-delta intraepithelial T cell number J:110846
decreased lymphocyte cell number J:110846
increased gamma-delta T cell number J:110846
Ccr10tm1.1Nax/Ccr10tm1.1Nax
(B6.129S4(Cg)-Ccr10tm1.1Nax)
decreased gamma-delta intraepithelial T cell number J:165323
Ccr10tm1Cge/Ccr10tm1Cge
(C.129S4-Ccr10tm1Cge)
abnormal leukocyte migration J:140728
abnormal plasma cell morphology J:140728
decreased IgA level J:140728
Ccrl2tm1Lex/Ccrl2tm1Lex
(involves: 129S/SvEvBrd * C57BL/6)
decreased susceptibility to type I hypersensitivity reaction J:140110
Ccrl2tm1Ssoz/Ccrl2tm1Ssoz
(B6.129-Ccrl2tm1Ssoz)
abnormal dendritic cell chemotaxis J:165873
abnormal hypersensitivity reaction J:165873
abnormal T-helper 2 physiology J:165873
decreased interleukin-4 secretion J:165873
decreased interleukin-5 secretion J:165873
decreased interleukin-13 secretion J:165873
lymph node hypoplasia J:165873
Cd1tm1Gru/Cd1tm1Gru
(involves: 129S2/SvPas * BALB/c)
abnormal eosinophil cell number J:84720
absent NK T cells J:47769
decreased CD4-positive, alpha-beta T cell number J:126220
decreased interleukin-4 secretion J:47769
decreased susceptibility to infection induced morbidity/mortality J:126220
immune system phenotype J:47769
myocarditis J:126220
Cd1d1em1(IMPC)H/Cd1d1em1(IMPC)H
(C57BL/6NTac-Cd1d1em1(IMPC)H/H)
increased basophil cell number J:211773
Cd1d1tm1.1Aben/Cd1d1tm1.1Aben
Lyz2tm1(cre)Ifo/Lyz2+

(B6.Cg-Cd1d1tm1.1Aben Lyz2tm1(cre)Ifo)
decreased interferon-gamma secretion J:183087
decreased interleukin-4 secretion J:183087
immune system phenotype J:183087
Cd1d1tm1.1Aben/Cd1d1tm1.1Aben
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Cd1d1tm1.1Aben Tg(Cd4-cre)1Cwi)
decreased NK T cell number J:183087
Cd1d1tm1.1Aben/Cd1d1tm1.1Aben
Tg(Itgax-cre,-EGFP)4097Ach/0

(C57BL/6-Cd1d1tm1.1Aben Tg(Itgax-cre,-EGFP)4097Ach)
decreased interferon-gamma secretion J:183087
decreased interleukin-4 secretion J:183087
immune system phenotype J:183087
Cd1d1tm1.1Boes/Cd1d1tm1.1Boes
(involves: C57BL/6)
abnormal dendritic cell antigen presentation J:151699
abnormal interleukin-4 secretion J:151699
abnormal NK T cell morphology J:151699
abnormal NK T cell physiology J:151699
decreased interleukin-2 secretion J:151699
decreased NK T cell number J:151699
Cd1d1tm1.1Boes/Cd1d1tm1.1Boes
Cd74tm1Doi/Cd74tm1Doi

(involves: 129S2/SvPas * C57BL/6)
abnormal dendritic cell antigen presentation J:151699
Cd1d1tm1.2Aben/Cd1d1tm1.2Aben
(B6(C)-Cd1d1tm1.2Aben/J)
abnormal CD4-positive T cell differentiation J:177038
abnormal T cell activation J:177038
increased susceptibility to bacterial infection J:177038
increased susceptibility to bacterial infection induced morbidity/mortality J:177038
lung inflammation J:177038
Cd1d1tm1Crw/Cd1d1tm1Crw
(involves: 129S4/SvJae * C57BL/6)
decreased NK T cell number J:76976
Cd1d1tm1Crw/Cd1d1tm1Crw
(B6.129S4-Cd1d1tm1Crw)
decreased IgG level J:99107
decreased susceptibility to induced arthritis J:99107
Cd1d1tm1Luc/Cd1d1tm1Luc
(B6.129S6-Cd1d1tm1Luc)
autoimmune response J:122245
decreased regulatory T cell number J:122245
Cd1d1tm1Luc/Cd1d1tm1Luc
(involves: 129S6/SvEvTac * C57BL/6)
arrested T cell differentiation J:125679
decreased acute inflammation J:93915
decreased interferon-gamma secretion J:93915, J:39748
decreased interleukin-4 secretion J:39748
decreased NK T cell number J:39748
decreased tumor necrosis factor secretion J:93915
Cd1d1tm1Luc/Cd1d1tm1Luc
(C.129S6-Cd1d1tm1Luc)
decreased interleukin-4 secretion J:121187
glomerulonephritis J:121187
increased anti-double stranded DNA antibody level J:121187
increased anti-nuclear antigen antibody level J:121187
increased IgG3 level J:121187
kidney inflammation J:121187
Cd1d1tm1Luc/Cd1d1tm1Luc
Cx3cr1tm1Litt/Cx3cr1tm1Litt

(B6.129-Cd1d1tm1Luc Cx3cr1tm1Litt)
decreased NK cell number J:129712
increased susceptibility to experimental autoimmune encephalomyelitis J:129712
Cd1d1tm2Aben/Del(3Cd1d2-Cd1d1)1Crw
(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal antigen presentation J:174337
Cd1d1tm2Aben/Cd1d1tm2Aben
(B6.129P2-Cd1d1tm2Aben)
abnormal antigen presentation J:174337
decreased NK T cell number J:174337
Cd1d1tm2Aben/Cd1d1tm2Aben
(involves: 129P2/OlaHsd * C57BL/6)
abnormal antigen presentation J:174337
decreased NK T cell number J:174337
Cd2apem1Irgu/Cd2apem1Irgu
(C57BL/6-Cd2apem1Irgu)
kidney inflammation J:294238
Cd2aptm1Shaw/Cd2aptm1Shaw
(involves: 129X1/SvJ)
decreased T cell proliferation J:57971
spleen atrophy J:57971
thymus atrophy J:57971
Cd2bp2tm1.1Tbh/Cd2bp2tm1.1Tbh
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * CBA/J)
impaired macrophage phagocytosis J:283435
Cd3dtm1Kap/Cd3dtm1Kap
(C57BL/6-Cd3dtm1Kap)
arrested T cell differentiation J:39925
decreased CD4-positive, alpha-beta T cell number J:39925
decreased CD8-positive, alpha-beta T cell number J:39925
Cd3em1Btlr/Cd3em1Btlr
(C57BL/6J-Cd3em1Btlr)
abnormal thymus morphology J:132486
absent T cells J:132486
arrested T cell differentiation J:132486
increased T cell apoptosis J:132486
small thymus J:132486
Cd3em1Btlr/Cd3em1Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
Cd3em2Btlr/Cd3em2Btlr
(C57BL/6J-Cd3em2Btlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:274934
abnormal T cell differentiation J:274934
decreased CD4-positive, alpha-beta T cell number J:274934
decreased CD8-positive, naive alpha-beta T cell number J:274934
increased CD8-positive, alpha-beta T cell number J:274934
increased central memory CD8 positive, alpha-beta T cell number J:274934
Cd3etm1.1Geno/Cd3etm1.1Geno
(involves: C57BL/6)
abnormal double-positive T cell morphology J:192604
abnormal T cell differentiation J:192604
abnormal T cell number J:192604
increased DN3 thymocyte number J:192604
Cd3etm1.1Geno/Cd3etm1.1Geno
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C57BL/6 * C57BL/6J * DBA/2J)
abnormal negative T cell selection J:192604
abnormal positive T cell selection J:192604
increased DN3 thymocyte number J:192604
Cd3etm1.1Geno/Cd3etm1.1Geno
Tg(TcrAND)53Hed/0

(involves: C57BL/6 * SJL)
abnormal CD4-positive T cell differentiation J:192604
abnormal positive T cell selection J:192604
increased DN3 thymocyte number J:192604
Cd3etm1.1Geno/Cd3etm1.1Geno
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6)
abnormal positive T cell selection J:192604
abnormal T cell differentiation J:192604
abnormal thymus cell ratio J:192604
decreased double-positive T cell number J:192604
decreased T cell number J:192604
increased DN3 thymocyte number J:192604
Cd3etm1.1Lov/Cd3etm1.1Lov
(Not Specified)
abnormal T cell morphology J:72144
arrested T cell differentiation J:72144
decreased double-positive T cell number J:72144
increased double-negative T cell number J:72144
Cd3etm1.1Lov/Cd3etm1.1Lov
Trdctm1Mal/Trdctm1Mal

(involves: C57BL/6)
abnormal double-negative T cell morphology J:112658
Cd3etm1Cpt/Cd3etm1Cpt
(involves: 129S4/SvJae * C57BL/6)
absent T cells J:54756
decreased double-positive T cell number J:54756
thymus hypoplasia J:54756
Cd3etm1Cpt/Cd3etm1Cpt
Tg(CD3E)26Cpt/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
decreased double-positive T cell number J:54756
decreased T cell number J:54756
thymus hypoplasia J:54756
Cd3etm1Lov/Cd3etm1Lov
(involves: 129S1/Sv * 129X1/SvJ)
abnormal T cell morphology J:72144
arrested T cell differentiation J:72144
decreased double-positive T cell number J:72144
increased double-negative T cell number J:72144
Cd3etm1Mal/Cd3etm1Mal
(involves: C57BL/6)
absent CD4-positive, alpha-beta T cells J:77098
absent CD8-positive, alpha-beta T cells J:77098
arrested T cell differentiation J:77098
Cd3etm1Mal/Cd3etm1Mal
(C57BL/6-Cd3etm1Mal)
abnormal B cell morphology J:81133
abnormal double-negative T cell morphology J:81133
abnormal regulatory T cell physiology J:125748
absent T cells J:131351
arrested T cell differentiation J:81133
Cd3etm1Mal/Cd3etm1Mal
Lattm1.1Mal/Lattm1.1Mal

(involves: 129S2/SvPas * C57BL/6)
absent CD4-positive, alpha-beta T cells J:77098
absent CD8-positive, alpha-beta T cells J:77098
arrested T cell differentiation J:77098
immune system phenotype J:77098
Cd3etm1Mal/Cd3etm1Mal
Nlrp1aNeut1/Nlrp1aNeut1

(involves: C57BL/6)
increased neutrophil cell number J:191055
increased susceptibility to infection induced morbidity/mortality J:191055
skin inflammation J:191055
Cd3gtm1.1Cage/Cd3gtm1.1Cage
(B6.129P2-Cd3gtm1.1Cage)
abnormal response to infection J:153813
decreased CD8-positive, alpha-beta T cell number J:153813
decreased thymocyte number J:153813
increased T cell apoptosis J:153813
spleen hypoplasia J:153813
Cd3gtm1.1Cage/Cd3gtm1.1Cage
Tg(TcrLCMV)318Sdz/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N)
abnormal response to infection J:142387
abnormal T cell physiology J:142387
immune system phenotype J:142387
Cd3gtm1Amk/Cd3gtm1Amk
(involves: 129P2/OlaHsd)
abnormal CD8-positive, alpha-beta T cell physiology J:77504
abnormal T cell activation J:77504
abnormal T cell differentiation J:77504
abnormal T cell physiology J:77504
abnormal T cell proliferation J:77504
decreased cytotoxic T cell cytolysis J:77504
decreased thymocyte number J:114561
lymph node hypoplasia J:77504
thymus hypoplasia J:77504
Cd3gtm1Amk/Cd3gtm1Amk
Tg(Igh-Pim1)1Brn/0

(involves: 129P2/OlaHsd * C57BL/6LiA * CBA)
decreased thymocyte number J:114561
Cd3gtm2Amk/Cd3gtm2Amk
(involves: 129P2/OlaHsd * FVB)
immune system phenotype J:77504
Cd4del/Cd4del
(C57BR/cdJ-Cd4del)
abnormal immune system organ morphology J:46692
abnormal lymph node T cell domain morphology J:46692
abnormal spleen morphology J:46692
absent CD4-positive, alpha-beta T cells J:46692
decreased IgG level J:46692
decreased IgM level J:46692
decreased immunoglobulin level J:46692
increased CD8-positive, alpha-beta T cell number J:46692
Cd4em1Litt/Cd4em1Litt
(involves: C57BL/6J)
immune system phenotype J:333574
Cd4em1Litt/Cd4em1Litt
Rr386em1Pdi/Rr386em1Pdi

(involves: C57BL/6J)
abnormal lymphocyte activation involved in immune response J:333574
decreased T helper 1 cell number J:333574
immune system phenotype J:333574
Cd4m1Btlr/Cd4m1Btlr
(C57BL/6J-Cd4m1Btlr)
absent CD4-positive, alpha-beta T cells J:212900
impaired humoral immune response J:212900
Cd4maat/Cd4maat
(C57BL/6JAnu-Cd4maat/Apb)
abnormal CD4-positive, alpha beta T cell morphology J:104190
abnormal double-positive T cell morphology J:104190
decreased CD4-positive, alpha-beta T cell number J:104190
increased CD8-positive, alpha-beta T cell number J:104190
Cd4sesh/Cd4sesh
(C57BL/6JAnu-Cd4sesh/AnuApb)
abnormal CD4-positive, alpha beta T cell morphology J:104190
abnormal double-positive T cell morphology J:104190
decreased T cell number J:104190
Cd4thth/Cd4thth
(C57BL/6JSfdAnu-Cd4thth)
absent CD4-positive, alpha-beta T cells J:104190
Cd4tm1(cre/ERT2)Thbu/Cd4+
Gfm1tm1c(EUCOMM)Wtsi/Gfm1tm1c(EUCOMM)Wtsi

(involves: C57BL/6 * C57BL/6N * SJL)
abnormal T-helper 17 cell differentiation J:302272
decreased susceptibility to experimental autoimmune encephalomyelitis J:302272
increased CD8-positive, alpha-beta T cell number J:302272
increased single-positive T cell number J:302272
Cd4tm1(cre/ERT2)Thbu/Cd4+
Tgfbr2tm1Karl/Tgfbr2tm1Karl

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:204579
increased memory T cell number J:204579
increased regulatory T cell number J:204579
Cd4tm1Doi/Cd4tm1Doi
Lag3tm1Doi/Lag3tm1Doi

(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:33272
increased double-negative T cell number J:33272
Cd4tm1Doi/Cd4tm1Litt
Lag3tm1Doi/Lag3+

(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:33272
increased double-negative T cell number J:33272
Cd4tm1Jrp/Cd4tm1Jrp
(either: B6.129S2-Cd4tm1Jrp or B10.Cg-Cd4tm1Jrp)
abnormal T cell differentiation J:45168
decreased CD4-positive, alpha-beta T cell number J:45168
decreased double-positive T cell number J:45168
increased CD8-positive, alpha-beta T cell number J:45168
Cd4tm1Jrp/Cd4tm1Jrp
Tg(TcrAND)53Hed/0

(either: (involves: 129S2/SvPas * C57BL/6 * SJL) or (involves: 129S2/SvPas * C57BL/6 * C57BL/10 * SJL))
abnormal T cell number J:45168
thymus hyperplasia J:45168
Cd4tm1Knw/Cd4tm1Knw
(B6.129S-Cd4tm1Knw/J)
decreased CD4-positive, alpha-beta T cell number J:87828
increased CD8-positive, alpha-beta T cell number J:87828
increased susceptibility to parasitic infection J:87828
Cd4tm1Knw/Cd4tm1Knw
(NOD.Cg-Cd4tm1Knw)
decreased susceptibility to autoimmune diabetes J:93553
Cd4tm1Knw/Cd4tm1Knw
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0

(NOD.Cg-Cd4tm1Knw Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs)
increased susceptibility to autoimmune diabetes J:93553
Cd4tm1Litt/Cd4tm1Litt
(involves: 129S2/SvPas)
abnormal CD4-positive, alpha-beta T cell physiology J:50435
absent CD4-positive, alpha-beta T cells J:50435
decreased CD4-positive, alpha-beta T cell number J:158962
decreased T cell proliferation J:50435
increased CD8-positive, alpha-beta T cell number J:158962, J:50435
Cd4tm1Litt/Cd4tm1Litt
Foxp3sfOtcspf/Y

(involves: 129/Rl * 129S2/SvPas)
abnormal CD8-positive, alpha beta T cell morphology J:20865
abnormal cytokine secretion J:20865
abnormal immune system organ morphology J:20865
enlarged lymph nodes J:20865
increased IgG level J:20865
increased IgM level J:20865
increased interleukin-4 secretion J:20865
increased interleukin-6 secretion J:20865
increased tumor necrosis factor secretion J:20865
Cd4tm1Litt/Cd4tm1Litt
Tg(Cd4-CD4)2362Litt/0

(involves: 129S2/SvPas * C57BL/6 * SJL)
immune system phenotype J:50435
Cd4tm1Litt/Cd4tm1Nik
Tg(Lck-cre)3778Nik/0

(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:73479
abnormal interleukin-4 secretion J:73479
abnormal T-helper 2 physiology J:73479
decreased T cell proliferation J:73479
Cd4tm1Litt/Cd4tm1Nik
Tg(Lck-cre)3785Nik/0

(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:73479
decreased CD4-positive, alpha-beta T cell number J:73479
increased CD8-positive, alpha-beta T cell number J:73479
increased T cell apoptosis J:73479
increased T cell proliferation J:73479
Cd4tm1Litt/Cd4tm1Nik
Tg(Lck-icre)3779Nik/0

(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:73479
decreased T cell proliferation J:73479
Cd4tm1Mak/Cd4tm1Mak
(involves: 129S2/SvPas * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:68957
increased CD8-positive, alpha-beta T cell number J:68957
increased susceptibility to Picornaviridae infection J:92227
Cd4tm1Mak/Cd4tm1Mak
(PL.129S2(B6)-Cd4tm1Mak/Rdgz)
brain inflammation J:92227
increased susceptibility to Picornaviridae infection J:92227
Cd4tm1Mak/Cd4tm1Mak
(SJL.129S2(B6)-Cd4tm1Mak/Rdgz)
brain inflammation J:92227
increased susceptibility to Picornaviridae infection J:92227
Cd4tm1Mak/Cd4tm1Mak
(involves: 129S2/SvPas)
immune system phenotype J:110749
Cd4tm1Mak/Cd4tm1Mak
(B6.129S2-Cd4tm1Mak/J)
absent plasma cells J:133047
immune system phenotype J:133047
Cd4tm1Mak/Cd4tm1Mak
Cd8atm1Mak/Cd8atm1Mak

(involves: 129S2/SvPas * C57BL/6 * DBA/2)
abnormal double-negative T cell morphology J:12572
abnormal gamma-delta T cell number J:12572
abnormal T cell differentiation J:12572
abnormal T cell number J:12572
decreased cytotoxic T cell cytolysis J:12572
decreased double-positive T cell number J:12572
increased length of allograft survival J:12572
small thymus medulla J:12572
Cd4tm1Mak/Cd4tm1Mak
Cd8atm1Mak/Cd8atm1Mak

(involves: 129S2/SvPas)
increased susceptibility to viral infection J:110749
Cd4tm1Mak/Cd4tm1Mak
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+

(B6.Cg-Cd4tm1Mak Igh-Jtm2(3H9-VDJ*)Mwg)
increased anti-double stranded DNA antibody level J:142389
Cd4tm1Mak/Cd4tm1Mak
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6J)
small intestinal inflammation J:108572
Cd4tm1Nik/Cd4tm1Nik
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129X1/SvJ)
abnormal regulatory T cell physiology J:152472
Cd4ts1BALB/c/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd4ts2DBA/2/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd4ts3BALB/c/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd4ts4C3H/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd4ts5BALB/c/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd4ts5C57BL/6/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased memory T cell number J:83220
Cd4ts6DBA/2/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd4vts1DBA/2/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd5tm1.1(KOMP)Mbp/Cd5tm1.1(KOMP)Mbp
(C57BL/6N-Cd5tm1.1(KOMP)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Cd5tm1.1Chra/Cd5tm1.1Chra
(involves: C57BL/6 * FVB/N)
abnormal T cell anergy J:189919
abnormal T cell physiology J:189919
decreased B cell number J:189919
decreased CD4-positive, alpha-beta T cell number J:189919
decreased double-positive T cell number J:189919
decreased follicular B cell number J:189919
decreased susceptibility to experimental autoimmune encephalomyelitis J:189919
decreased T cell proliferation J:189919
decreased T-helper 17 cell number J:189919
increased double-negative T cell number J:189919
increased T cell proliferation J:189919
Cd5tm1.1Chra/Cd5tm1.1Chra
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: C57BL/6 * FVB/N)
decreased interferon-gamma secretion J:189919
decreased interleukin-2 secretion J:189919
decreased T cell proliferation J:189919
decreased T helper 1 cell number J:189919
increased interferon-gamma secretion J:189919
increased interleukin-6 secretion J:189919
increased interleukin-17 secretion J:189919
Cd5tm1Cgn/Cd5tm1Cgn
(B6.129P2-Cd5tm1Cgn)
abnormal T cell anergy J:189919
decreased susceptibility to experimental autoimmune encephalomyelitis J:189919
increased regulatory T cell number J:189919
increased T cell proliferation J:189919
Cd5ltm1Nto/Cd5ltm1Nto
(involves: 129P2/OlaHsd * C57BL/6)
abnormal double-positive T cell morphology J:52195
decreased thymocyte number J:52195
immune system phenotype J:52195
increased susceptibility to bacterial infection J:82352
Cd6tm1Linf/Cd6tm1Linf
(D1.Cg-Cd6tm1Linf)
abnormal B cell physiology J:238478
decreased B cell proliferation J:238478
decreased B-1 B cell number J:238478
decreased B-1a cell number J:238478
decreased IgM level J:238478
decreased interleukin-6 secretion J:238478
increased B-1a cell number J:238478
increased B-1b cell number J:238478
Cd7tm1Bfh/Cd7tm1Bfh
(involves: 129 * C57BL/6)
immune system phenotype J:48758
increased double-positive T cell number J:48758
increased thymocyte number J:48758
Cd7tm1Bfh/Cd7tm1Bfh
(B6.129-Cd7tm1Bfh)
decreased cytotoxic T cell cytolysis J:48758
decreased interferon-gamma secretion J:48758
immune system phenotype J:48758
increased double-positive T cell number J:48758
increased thymocyte number J:48758
Cd7tm1Fabo/Cd7tm1Fabo
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:45026
Cd8am1Btlr/Cd8am1Btlr
(C57BL/6J-Cd8am1Btlr)
abnormal CD4-positive T cell differentiation J:221492
abnormal CD8-positive, alpha-beta T cell differentiation J:221492
increased susceptibility to Herpesvirales infection J:221492
Cd8am2Btlr/Cd8am2Btlr
(C57BL/6J-Cd8am2Btlr)
abnormal CD8-positive, alpha-beta T cell physiology J:236677
increased CD8-positive, alpha-beta memory T cell proliferation J:236677
Cd8atm1.1(cre)Koni/Cd8atm1.1(cre)Koni
(involves: C57BL/6J * C57BL/6NHsd * SJL)
decreased CD8-positive, alpha-beta T cell number J:177182
Cd8atm1.1Kio/Cd8atm1.1Kio
(involves: 129S4/SvJae * C57BL/10 * CBA/Ca)
abnormal CD4-positive T cell differentiation J:76799
Cd8atm1.1Litt/Cd8atm1.1Litt
(either: (involves: 129P2/OlaHsd * AKR) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal CD8-positive, alpha beta T cell morphology J:50624
Cd8atm1.1Welm/Cd8atm1.1Welm
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:113136
Cd8atm1Asin/Cd8atm1Asin
(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
abnormal double-positive T cell morphology J:126026
Cd8atm1Asin/Cd8atm1Asin
Cd8b1tm1Litt/Cd8b1tm1Litt
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru

(involves: 129 * FVB/N)
decreased CD4-positive, alpha-beta T cell number J:126026
increased CD8-positive, alpha-beta T cell number J:126026
Cd8atm1Asin/Cd8atm1Asin
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J)
abnormal CD8-positive, alpha beta T cell morphology J:125259
Cd8atm1Asin/Cd8atm1Asin
Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/10 * FVB/N)
abnormal positive T cell selection J:126026
decreased CD4-positive, alpha-beta T cell number J:126026
increased CD8-positive, alpha-beta T cell number J:126026
Cd8atm1Asin/Cd8atm1Mak
(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * FVB/N)
abnormal positive T cell selection J:126026
abnormal T cell subpopulation ratio J:126026
increased CD8-positive, alpha-beta T cell number J:126026
Cd8atm1Mak/Cd8atm1Mak
(involves: 129S2/SvPas * C57BL/6 * DBA/2)
abnormal cytotoxic T cell physiology J:68956
absent CD8-positive, alpha-beta T cells J:68956
increased susceptibility to Picornaviridae infection J:92227
Cd8atm1Mak/Cd8atm1Mak
(PL.129S2(B6)-Cd8atm1Mak/Rdgz)
increased susceptibility to Picornaviridae infection J:92227
Cd8atm1Mak/Cd8atm1Mak
(SJL.129S2(B6)-Cd8atm1Mak/Rdgz)
increased susceptibility to Picornaviridae infection J:92227
Cd8atm1Mak/Cd8atm1Mak
(B6.129S2-Cd8atm1Mak)
abnormal response to transplant J:91742
Cd8atm1Mak/Cd8atm1Mak
(involves: 129S2/SvPas)
immune system phenotype J:110749
Cd8atm1Mak/Cd8atm1Mak
Il15tm1Imx/Il15tm1Imx
X/Yaa

(BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr)
abnormal spleen B cell follicle morphology J:179430
increased anti-nuclear antigen antibody level J:179430
increased IgG1 level J:179430
increased IgG2a level J:179430
increased IgG2b level J:179430
increased monocyte cell number J:179430
increased splenocyte number J:179430
increased susceptibility to systemic lupus erythematosus J:179430
Cd8atm1Mak/Cd8atm1Mak
X/Yaa

(BXSB.129S2(B6)-Cd8atm1Mak/4Dcr)
increased susceptibility to systemic lupus erythematosus J:179430
Cd8atm1Mak/Cd8atm1Mak
Zbtb7bhd/Zbtb7bhd

(involves: B6.129S2-Cd8atm1Mak * B6.Cg-Thpokhd)
absent CD4-positive, alpha-beta T cells J:95867
Cd8b1M1Btlr/Cd8b1+
(C57BL/6J-Cd8b1M1Btlr)
decreased CD8-positive, naive alpha-beta T cell number J:255009
increased CD4-positive, alpha-beta T cell number J:255009
Cd8b1M1Btlr/Cd8b1M1Btlr
(C57BL/6J-Cd8b1M1Btlr)
decreased CD8-positive, naive alpha-beta T cell number J:255009
enhanced humoral immune response J:255009
increased CD4-positive, alpha-beta T cell number J:255009
increased IgG level J:255009
Cd8b1m2Btlr/Cd8b1m2Btlr
(C57BL/6J-Cd8b1m2Btlr)
abnormal B cell differentiation J:274761
abnormal CD8-positive, alpha-beta T cell differentiation J:274761
decreased CD8-positive, alpha-beta T cell number J:274761
decreased CD8-positive, naive alpha-beta T cell number J:274761
decreased T cell number J:274761
increased CD4-positive, alpha-beta T cell number J:274761
increased central memory CD8 positive, alpha-beta T cell number J:274761
increased effector memory CD8-positive, alpha-beta T cell number J:274761
Cd8b1tm1Litt/Cd8b1+
Tg(Cd8b1)46Erob/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
abnormal T cell subpopulation ratio J:110916
decreased T cell number J:110916
decreased thymocyte number J:110916
Cd8b1tm1Litt/Cd8b1+
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129S4/SvJae * C57BL/6J * DBA/2)
decreased double-positive T cell number J:112551
Cd8b1tm1Litt/Cd8b1tm1Litt
(involves: 129S4/SvJae * C57BL/6J)
abnormal cytotoxic T cell physiology J:112551
abnormal T cell subpopulation ratio J:110916
decreased CD8-positive, alpha-beta T cell number J:112551, J:110916
decreased thymocyte number J:110916
Cd8b1tm1Litt/Cd8b1tm1Litt
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129S4/SvJae * C57BL/6J * DBA/2)
abnormal lymph node cell ratio J:112551
abnormal negative T cell selection J:112551
abnormal positive T cell selection J:112551
decreased CD8-positive, alpha-beta T cell number J:112551
increased CD4-positive, alpha-beta T cell number J:112551
Cd8b1tm1Wpfl/Cd8b1tm1Wpfl
(involves: 129S2/SvPas)
abnormal CD8-positive, alpha beta T cell morphology J:19928
abnormal CD8-positive, alpha-beta T cell differentiation J:19928
abnormal T cell subpopulation ratio J:19928
decreased CD8-positive, alpha-beta T cell number J:19928
decreased thymocyte number J:19928
immune system phenotype J:19928
Cd8mts1DBA/2/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased memory T cell number J:83220
Cd8mts2BALB/c/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased memory T cell number J:83220
Cd8mts3C57BL/6/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased memory T cell number J:83220
Cd8mts4DBA/2/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased memory T cell number J:83220
Cd8mts5BALB/c/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd8mts5C57BL/6/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased memory T cell number J:83220
Cd8mts6C3H/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased CD8-positive, alpha-beta T cell number J:83220
Cd8ts1DBA/2/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased CD8-positive, alpha-beta T cell number J:83220
Cd8ts2C57BL/6/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased CD8-positive, alpha-beta T cell number J:83220
Cd8ts3C3H/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased CD8-positive, alpha-beta T cell number J:83220
Cd8ts3DBA/2/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Cd14hdl/Cd14hdl
(C57BL/6-Cd14hdl)
abnormal interferon secretion J:98908
decreased susceptibility to endotoxin shock J:98908
decreased tumor necrosis factor secretion J:98908
increased susceptibility to Riboviria infection J:98908
Cd14tm1Frm/Cd14+
(involves: 129S4/SvJae * C57BL/6J)
abnormal cytokine secretion J:65107
decreased interleukin-6 secretion J:65107
decreased tumor necrosis factor secretion J:65107
Cd14tm1Frm/Cd14tm1Frm
(involves: 129S4/SvJae * C57BL/6J)
abnormal cytokine secretion J:65107
decreased interleukin-6 secretion J:65107
decreased tumor necrosis factor secretion J:65107
Cd14tm1Frm/Cd14tm1Frm
(involves: 129S4/SvJae)
abnormal interferon secretion J:98908
decreased susceptibility to endotoxin shock J:98908
increased susceptibility to Riboviria infection J:98908
Cd14tm1Frm/Cd14tm1Frm
(B6.129S4-Cd14tm1Frm)
abnormal cytokine level J:96680
abnormal interleukin level J:96680
abnormal tumor necrosis factor level J:96680
Cd14tm1Smg/Cd14tm1Smg
(involves: 129S1/Sv * C57BL/6)
decreased circulating interleukin-6 level J:32729
decreased circulating tumor necrosis factor level J:32729
decreased interleukin-6 secretion J:32729
decreased susceptibility to bacterial infection J:32729
decreased susceptibility to bacterial infection induced morbidity/mortality J:32729
decreased susceptibility to endotoxin shock J:32729
decreased tumor necrosis factor secretion J:32729
Cd14tm1Smg/Cd14tm1Smg
(C.129S1-CD14tm1Smg)
abnormal macrophage physiology J:116691
abnormal neutrophil physiology J:127072
decreased susceptibility to bacterial infection J:127072
decreased tumor necrosis factor secretion J:116691
Cd14tm1Smg/Cd14tm1Smg
(B6.129S1-CD14tm1Smg)
decreased susceptibility to bacterial infection J:127072
Cd14tm1Smg/Cd14tm1Smg
(involves: 129S1/Sv)
abnormal tumor necrosis factor level J:103464
Cd14tm1Smg/Cd14tm1Smg
Tlr4Lps-d/Tlr4Lps-d

(C3.129S1-CD14tm1Smg)
abnormal macrophage physiology J:116691
decreased tumor necrosis factor secretion J:116691
Cd19em2(IMPC)Ics/Cd19em2(IMPC)Ics
(C57BL/6N-Cd19em2(IMPC)Ics/Ics)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Cd19tm1(cre)Cgn/?
Gt(ROSA)26Sortm1(HBEGF)Awai/Gt(ROSA)26Sortm1(HBEGF)Awai

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell morphology J:131076
abnormal lymph node cell ratio J:131076
abnormal lymphocyte cell number J:131076
abnormal lymphocyte morphology J:131076
abnormal splenic cell ratio J:131076
absent immature B cells J:131076
absent mature B cells J:131076
Cd19tm1(cre)Cgn/Cd19+
Cd1d1tm1.1Aben/Cd1d1tm1.1Aben

(B6.Cg-Cd1d1tm1.1Aben Cd19tm1(cre)Cgn)
immune system phenotype J:183087
Cd19tm1(cre)Cgn/Cd19+
Ctnnbl1tm1.1Crad/Ctnnbl1tm1.1Crad

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
decreased B cell proliferation J:232010
Cd19tm1(cre)Cgn/Cd19+
Cxcr4tm1Tng/Cxcr4tm2Tng

(involves: 129P2/OlaHsd * C57BL/6)
decreased plasma cell number J:109147
Cd19tm1(cre)Cgn/Cd19+
Derl2tm1.1Hpl/Derl2tm1.1Hpl

(involves: 129P2/OlaHsd)
immune system phenotype J:170650
Cd19tm1(cre)Cgn/Cd19+
Ell2tm1.1Cmil/Ell2tm1.1Cmil

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
decreased IgA level J:234692
decreased IgG1 level J:234692
decreased IgM level J:234692
decreased immunoglobulin level J:234692
decreased mature B cell number J:234692
decreased plasma cell number J:234692
decreased transitional stage T1 B cell number J:234692
decreased transitional stage T2 B cell number J:234692
decreased transitional stage T3 B cell number J:234692
impaired humoral immune response J:234692
increased follicular B cell number J:234692
increased immature B cell number J:234692
increased pre-B cell number J:234692
increased pro-B cell number J:234692
Cd19tm1(cre)Cgn/Cd19+
Ell2tm2.1Cmil/Ell2tm2.1Cmil

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
decreased IgA level J:234692
decreased IgG1 level J:234692
decreased IgM level J:234692
decreased immunoglobulin level J:234692
decreased mature B cell number J:234692
Cd19tm1(cre)Cgn/Cd19+
Ep300tm2Reck/Ep300+

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal adaptive immunity J:147840
abnormal B cell differentiation J:147840
abnormal humoral immune response J:147840
abnormal spleen marginal zone macrophage morphology J:147840
abnormal transitional stage B cell morphology J:147840
arteritis J:147840
decreased B cell proliferation J:147840
decreased marginal zone B cell number J:147840
enlarged lymph nodes J:147840
enlarged spleen J:147840
glomerulonephritis J:147840
increased activated T cell number J:147840
increased anti-double stranded DNA antibody level J:147840
increased B cell apoptosis J:147840
increased B cell number J:147840
increased IgG2b level J:147840
increased immunoglobulin level J:147840
increased spleen weight J:147840
increased susceptibility to systemic lupus erythematosus J:147840
intermingled spleen red and white pulp J:147840
kidney inflammation J:147840
Cd19tm1(cre)Cgn/Cd19+
Ep300tm2Reck/Ep300+

(involves: 129/Sv * 129P2/OlaHsd * FVB/N)
increased susceptibility to systemic lupus erythematosus J:147840
Cd19tm1(cre)Cgn/Cd19+
Faslpr/Fastm1Cgn

(involves: 129P2/OlaHsd * C57BL/6 * MRL)
enlarged lymph nodes J:114948
enlarged spleen J:114948
Cd19tm1(cre)Cgn/Cd19+
Faslpr/Fastm1Cgn
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * MRL)
enlarged lymph nodes J:114948
enlarged spleen J:114948
increased double-negative T cell number J:114948
Cd19tm1(cre)Cgn/Cd19+
Fastm1Ach/Fastm1Ach

(involves: 129P2/OlaHsd * BALB/c)
enlarged spleen J:123556
increased anti-nuclear antigen antibody level J:123556
increased immunoglobulin level J:123556
increased lymphocyte cell number J:123556
Cd19tm1(cre)Cgn/Cd19+
Fastm1Cgn/Fastm1Cgn

(B6.Cg-Cd19tm1(cre)Cgn Fastm1Cgn)
increased anti-single stranded DNA antibody level J:114948
Cd19tm1(cre)Cgn/Cd19+
Gna12tm1Citb/Gna12tm1Citb
Gna13tm2.1Soff/Gna13tm2.1Soff

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6N)
abnormal B cell physiology J:117663
decreased marginal zone B cell number J:117663
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm1(CTNNB1)Nerl/Gt(ROSA)26Sortm1(CTNNB1)Nerl

(involves: 129P2/OlaHsd * BALB/c)
immune system phenotype J:112660
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd)
decreased B cell number J:92789
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd)
abnormal T cell activation J:160931
enlarged spleen J:160931
increased T cell proliferation J:160931
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm1Uzs/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * BALB/c)
immune system phenotype J:130768
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm2(CARD11*L225LI)Jrld/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd)
abnormal B cell activation J:228288
abnormal plasmablast number J:228288
abnormal spleen morphology J:228288
enlarged lymph nodes J:228288
enlarged spleen J:228288
increased B cell number J:228288
increased B cell proliferation J:228288
increased plasma cell number J:228288
spleen hyperplasia J:228288
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm2(CARD11*L225LI)Jrld/Gt(ROSA)26Sor+
Malt1tm1Mak/Malt1tm1Mak

(involves: 129P2/OlaHsd)
immune system phenotype J:228288
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm2(Cd74/MOG)Awai/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:140751
decreased susceptibility to experimental autoimmune encephalomyelitis J:140751
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm2(Cd74/MOG)Awai/Gt(ROSA)26Sor+
Il10tm1Roer/Il10tm1Roer

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:140751
decreased susceptibility to experimental autoimmune encephalomyelitis J:140751
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:113365
abnormal splenic cell ratio J:113365
decreased B cell apoptosis J:113365
increased B cell number J:113365
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:113365
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm5(Map3k14)Rsky/Gt(ROSA)26Sortm5(Map3k14)Rsky

(involves: 129P2/OlaHsd * C57BL/6)
enlarged lymph nodes J:139293
enlarged spleen J:139293
increased marginal zone B cell number J:139293
increased mature B cell number J:139293
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm5(Map3k14)Rsky/Gt(ROSA)26Sortm5(Map3k14)Rsky
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass

(involves: 129P2/OlaHsd * C57BL/6)
decreased lymphocyte cell number J:139293
decreased mature B cell number J:139293
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm6(Map3k14*)Rsky/Gt(ROSA)26Sortm6(Map3k14*)Rsky

(involves: 129P2/OlaHsd * C57BL/6)
abnormal Peyer's patch morphology J:139293
abnormal spleen B cell follicle morphology J:139293
decreased B-1 B cell number J:139293
enlarged lymph nodes J:139293
enlarged spleen J:139293
increased mature B cell number J:139293
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm6(Map3k14*)Rsky/Gt(ROSA)26Sortm6(Map3k14*)Rsky
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass

(involves: 129P2/OlaHsd * C57BL/6)
increased lymphocyte cell number J:139293
increased mature B cell number J:139293
Cd19tm1(cre)Cgn/Cd19+
Ifnar1tm1Uka/Ifnar1tm1Uka

(B6.129P2-Cd19tm1(cre)Cgn Ifnar1tm1Uka)
decreased IgG1 level J:129128
decreased IgG2a level J:129128
decreased IgG3 level J:129128
decreased IgM level J:129128
Cd19tm1(cre)Cgn/Cd19+
Igbp1tm1Imku/Y

(involves: 129P2/OlaHsd)
abnormal B cell physiology J:74619
abnormal somatic hypermutation frequency J:74619
abnormal spleen germinal center morphology J:74619
decreased B cell number J:74619
decreased B cell proliferation J:74619
decreased follicular B cell number J:74619
decreased immunoglobulin level J:74619
decreased pre-B cell number J:74619
Cd19tm1(cre)Cgn/Cd19+
Ikbkbtm1Cgn/Ikbkbtm1.1Cgn

(involves: 129P2/OlaHsd * C57BL/6)
decreased B-1 B cell number J:79132
decreased follicular B cell number J:79132
decreased immature B cell number J:79132
decreased marginal zone B cell number J:79132
decreased mature B cell number J:79132
increased B cell proliferation J:79132
Cd19tm1(cre)Cgn/Cd19+
Ikbkbtm2Cgn/Ikbkbtm2.1Cgn

(involves: 129P2/OlaHsd * C57BL/6)
decreased B-1 B cell number J:79132
decreased follicular B cell number J:79132
decreased marginal zone B cell number J:79132
decreased mature B cell number J:79132
Cd19tm1(cre)Cgn/Cd19+
Ikbkbtm2Mka/Ikbkbtm2Mka

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal B cell activation J:82995
decreased B cell number J:82995
decreased B cell proliferation J:82995
decreased B-1 B cell number J:82995
decreased IgG level J:82995
decreased IgM level J:82995
decreased marginal zone B cell number J:82995
increased B cell apoptosis J:82995
Cd19tm1(cre)Cgn/Cd19+
Ikbkgtm1.1Mpa/Y

(involves: 129P2/OlaHsd * C57BL/6)
decreased B-1 B cell number J:79132
decreased follicular B cell number J:79132
decreased immature B cell number J:79132
decreased marginal zone B cell number J:79132
decreased mature B cell number J:79132
increased B cell proliferation J:79132
Cd19tm1(cre)Cgn/Cd19+
Il10tm1Roer/Il10tm1Roer

(involves: 129P2/OlaHsd)
abnormal CD8-positive, alpha-beta T cell physiology J:151551
abnormal myeloid leukocyte morphology J:151551
decreased circulating interleukin-10 level J:151551
increased B cell number J:151551
increased CD4-positive, alpha-beta T cell number J:151551
increased plasma cell number J:151551
Cd19tm1(cre)Cgn/Cd19+
Il10ratm1.1Jack/Il10ratm1.1Jack

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
immune system phenotype J:157787
Cd19tm1(cre)Cgn/Cd19+
Inpp5dtm1Rav/Inpp5dtm1Rav
Ptentm1Hwu/Ptentm1Hwu

(involves: 129P2/OlaHsd * 129S4/SvJae)
abnormal B cell morphology J:166155
abnormal B cell physiology J:166155
abnormal myeloid leukocyte morphology J:166155
decreased B cell number J:166155
enlarged spleen J:166155
increased B cell number J:166155
increased B cell proliferation J:166155
increased spleen white pulp amount J:166155
Cd19tm1(cre)Cgn/Cd19+
Irf8tm1.1Hm/Irf8tm1.1Hm

(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen marginal zone morphology J:168923
decreased follicular B cell number J:168923
immune system phenotype J:168923
increased B cell number J:168923
increased B-2 B cell number J:168923
increased follicular B cell number J:168923
increased marginal zone B cell number J:168923
increased transitional stage B cell number J:168923
Cd19tm1(cre)Cgn/Cd19+
Klhl6tm2Sato/Klhl6tm2Sato

(either: (involves: 129P2/OlaHsd * 129T2/SvEms) or (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlaHsd * CD-1))
abnormal B cell differentiation J:101363
abnormal lymph node germinal center morphology J:101363
decreased B cell number J:101363
Cd19tm1(cre)Cgn/Cd19+
Kmt2atm1.1Erns/Kmt2atm1.1Erns

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL)
immune system phenotype J:147265
Cd19tm1(cre)Cgn/Cd19+
Ltbtm1Avt/Ltbtm1Avt

(involves: 129P2/OlaHsd * C57BL/6)
abnormal adaptive immunity J:79129
abnormal spleen B cell follicle morphology J:79129
abnormal spleen follicular dendritic cell network J:79129
decreased marginal zone B cell number J:79129
decreased spleen germinal center number J:79129
decreased spleen germinal center size J:79129
small Peyer's patches J:79129
Cd19tm1(cre)Cgn/Cd19+
Ltbtm1Avt/Ltbtm1Avt
Tg(Lck-cre)1Jtak/?

(involves: 129P2/OlaHsd * C57BL/6)
absent follicular dendritic cells J:79129
Cd19tm1(cre)Cgn/Cd19+
Ltbrtm1Avt/Ltbrtm1Avt

(involves: 129P2/OlaHsd)
immune system phenotype J:158663
Cd19tm1(cre)Cgn/Cd19+
Ltbrtm1Avt/Ltbrtm1Avt
Tg(Lck-cre)I57Jxm/0

(involves: 129P2/OlaHsd)
immune system phenotype J:158663
Cd19tm1(cre)Cgn/Cd19+
Map3k7tm1Aki/Map3k7tm1.1Aki

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:112597
decreased B cell proliferation J:112597
decreased B-1 B cell number J:112597
decreased IgG1 level J:112597
decreased IgG3 level J:112597
decreased IgG level J:112597
decreased immunoglobulin level J:112597
Cd19tm1(cre)Cgn/Cd19+
Mcl1tm2Sjk/Mcl1tm3Sjk

(involves: 129P2/OlaHsd * 129X1/SvJ)
abnormal B cell differentiation J:86906
absent early pro-B cells J:86906
absent late pro-B cells J:86906
absent pre-B cells J:86906
arrested B cell differentiation J:86906
decreased B cell number J:86906
increased B cell apoptosis J:86906
Cd19tm1(cre)Cgn/Cd19+
Mirc30tm1.1Rdf/Mirc30tm1.1Rdf

(involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
increased B cell number J:156946
increased B-1a cell number J:156946
increased spleen white pulp amount J:156946
Cd19tm1(cre)Cgn/Cd19+
Myd88em1.1Rsky/Myd88+

(involves: C57BL/6NTac)
abnormal splenic cell ratio J:308792
enlarged spleen J:308792
increased germinal center B cell number J:308792
increased IgM level J:308792
increased plasma cell number J:308792
Cd19tm1(cre)Cgn/Cd19+
Myd88em1.1Rsky/Myd88em1.1Rsky

(involves: C57BL/6NTac)
increased B cell proliferation J:308792
Cd19tm1(cre)Cgn/Cd19+
Notch2tm1.1Hhi/Notch2+

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased marginal zone B cell number J:83476
Cd19tm1(cre)Cgn/Cd19+
Notch2tm2Hhi/Notch2tm1.1Hhi

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal spleen marginal zone morphology J:83476
absent marginal zone B cells J:83476
decreased transitional stage B cell number J:83476
Cd19tm1(cre)Cgn/Cd19+
Pax5tm1Mbu/Pax5tm3Mbu

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal B cell differentiation J:75504
abnormal class switch recombination J:75504
decreased IgG1 level J:75504
decreased IgG3 level J:75504
decreased IgG level J:75504
decreased immature B cell number J:75504
decreased immunoglobulin level J:75504
decreased mature B cell number J:75504
decreased pre-B cell number J:75504
Cd19tm1(cre)Cgn/Cd19+
Pdia3tm1Gjh/Pdia3tm1Gjh

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:112606
Cd19tm1(cre)Cgn/Cd19+
Prdm1tm1Clme/Prdm1tm1Clme

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
abnormal B cell differentiation J:101890
abnormal memory B cell number J:101890
abnormal plasma cell differentiation J:101890
abnormal plasma cell morphology J:101890, J:114881
decreased IgG level J:101890
decreased IgM level J:101890
decreased immunoglobulin level J:101890
decreased plasma cell number J:101890
increased spleen germinal center number J:101890
increased spleen germinal center size J:101890
Cd19tm1(cre)Cgn/Cd19+
Ptentm1Hwu/Ptentm1Hwu

(involves: 129P2/OlaHsd * 129S4/SvJae)
abnormal B cell negative selection J:155314
abnormal B cell physiology J:83213
abnormal class switch recombination J:114881
abnormal plasma cell morphology J:114881
decreased IgG level J:114881
decreased spleen germinal center number J:83213
increased B cell apoptosis J:83213
increased B cell number J:83213
increased B cell proliferation J:155314, J:83213
increased B-1 B cell number J:83213
increased IgM level J:114881
increased marginal zone B cell number J:83213
Cd19tm1(cre)Cgn/Cd19+
Ptentm1Hwu/Ptentm1Hwu
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal peripheral B cell anergy J:155314
Cd19tm1(cre)Cgn/Cd19+
Ptpn6tm1Rsky/Ptpn6tm1Rsky

(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:123568
abnormal immune system physiology J:123568
abnormal leukocyte cell number J:123568
abnormal lymph organ size J:123568
decreased B cell proliferation J:123568
decreased follicular B cell number J:123568
decreased marginal zone B cell number J:123568
enlarged lymph nodes J:123568
enlarged spleen J:123568
increased B cell number J:123568
increased B-1a cell number J:123568
increased granulocyte number J:123568
increased macrophage cell number J:123568
increased plasma cell number J:123568
increased susceptibility to systemic lupus erythematosus J:123568
increased T cell number J:123568
Cd19tm1(cre)Cgn/Cd19+
Rac1tm1Tyb/Rac1tm1Tyb

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
immune system phenotype J:86765
Cd19tm1(cre)Cgn/Cd19+
Rac1tm1Tyb/Rac1tm1Tyb
Rac2tm1Mddw/Rac2tm1Mddw

(involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6)
arrested B cell differentiation J:86765
decreased B cell number J:86765
decreased B-1 B cell number J:86765
decreased follicular B cell number J:86765
decreased marginal zone B cell number J:86765
decreased transitional stage B cell number J:86765
Cd19tm1(cre)Cgn/Cd19+
Rapgef2tm1.1Hous/Rapgef2tm1.1Hous

(involves: 129P2/OlaHsd * 129S1/Sv)
immune system phenotype J:165879
Cd19tm1(cre)Cgn/Cd19+
Rbpjtm1Hon/Rbpjtm1Hon

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:76240
decreased marginal zone B cell number J:121523, J:76240
increased follicular B cell number J:121523, J:76240
increased IgG3 level J:76240
increased susceptibility to bacterial infection J:76240
increased susceptibility to bacterial infection induced morbidity/mortality J:76240
Cd19tm1(cre)Cgn/Cd19+
Rbpjtm1Hon/Rbpjtm1Hon
Spentm2.1Hon/Spentm2.1Hon

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased marginal zone B cell number J:121523
increased follicular B cell number J:121523
Cd19tm1(cre)Cgn/Cd19+
Slc3a2tm1.1Mgin/Slc3a2tm1.1Mgin

(involves: 129 * C57BL/6 * SJL)
abnormal B cell activation J:148000
abnormal B cell physiology J:148000
abnormal class switch recombination J:148000
abnormal plasma cell differentiation J:148000
decreased B cell proliferation J:148000
decreased germinal center B cell number J:148000
decreased IgG level J:148000
decreased IgM level J:148000
immune system phenotype J:148000
Cd19tm1(cre)Cgn/Cd19+
Slc3a2tm1.1Mgin/Slc3a2tm1Yai

(involves: 129 * C57BL/6 * SJL)
decreased IgG3 level J:148000
decreased IgM level J:148000
Cd19tm1(cre)Cgn/Cd19+
Spentm2.1Hon/Spentm2.1Hon

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased follicular B cell number J:121523
increased marginal zone B cell number J:121523
Cd19tm1(cre)Cgn/Cd19+
Srsf3tm1Pjln/Srsf3tm1Pjln

(involves: 129P2/OlaHsd * BALB/c)
decreased B cell number J:113645
Cd19tm1(cre)Cgn/Cd19+
Tbl1xr1tm1c(EUCOMM)Hmgu/Tbl1xr1tm1c(EUCOMM)Hmgu
Tg(Vav-BCL2)69Jad/0

(involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N)
abnormal B cell differentiation J:292118
abnormal lymphocyte morphology J:292118
abnormal spleen morphology J:292118
Cd19tm1(cre)Cgn/Cd19+
Tcf3tm1Mbu/Tcf3tm1.2Mbu

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
decreased B cell number J:137719
decreased immature B cell number J:137719
decreased mature B cell number J:137719
decreased pre-B cell number J:137719
decreased pro-B cell number J:137719
decreased transitional stage B cell number J:137719
Cd19tm1(cre)Cgn/Cd19+
Tcf3tm1Mbu/Tcf3tm1.2Mbu
Tg(Vav-BCL2)69Jad/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL)
decreased pre-B cell number J:137719
Cd19tm1(cre)Cgn/Cd19+
Tgfbr2tm1Roes/Tgfbr2tm1Roes

(involves: 129P2/OlaHsd * BALB/c)
abnormal B cell physiology J:90558
abnormal B-1 B cell morphology J:90558
abnormal B-1 B cell number J:90558
absent plasma cells J:90558
decreased IgA level J:90558
enlarged Peyer's patches J:90558
increased IgG level J:90558
increased IgM level J:90558
increased leukocyte cell number J:90558
Cd19tm1(cre)Cgn/Cd19+
Tnftm2.1Gkl/Tnftm2.1Gkl

(involves: 129P2/OlaHsd * 129S/SvEv * 129S6/SvEvTac * C57BL/6J)
immune system phenotype J:108572
Cd19tm1(cre)Cgn/Cd19+
Tnfaip3tm1.1Awai/Tnfaip3tm1.1Awai

(involves: 129P2/OlaHsd)
decreased B-1a cell number J:175422
decreased B-1b cell number J:175422
decreased marginal zone B cell number J:175422
decreased mature B cell number J:175422
enlarged spleen J:175422
increased anti-nuclear antigen antibody level J:175422
increased B cell number J:175422
increased B cell proliferation J:175422
increased follicular B cell number J:175422
increased germinal center B cell number J:175422
increased IgA level J:175422
increased IgG2a level J:175422
increased IgM level J:175422
increased splenocyte number J:175422
increased T cell number J:175422
Cd19tm1(cre)Cgn/Cd19+
Tnfaip3tm2Ama/Tnfaip3+

(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell apoptosis J:163917
increased autoantibody level J:163917
increased germinal center B cell number J:163917
increased immunoglobulin level J:163917
increased plasma cell number J:163917
increased susceptibility to autoimmune disorder J:163917
Cd19tm1(cre)Cgn/Cd19+
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:172843
Cd19tm1(cre)Cgn/Cd19+
Tnfsf13btm1Msc/Tnfsf13btm1Msc
Traf2tm1Rbr/Traf2tm1Rbr

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
increased follicular B cell number J:132877
increased marginal zone B cell number J:132877
Cd19tm1(cre)Cgn/Cd19+
Traf2tm1Rbr/Traf2tm1Rbr

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:132877
increased follicular B cell number J:132877
increased marginal zone B cell number J:132877
lymph node hyperplasia J:132877
Cd19tm1(cre)Cgn/Cd19+
Traf2tm1Rbr/Traf2tm1Rbr
Traf3tm1Rbr/Traf3tm1Rbr

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal B cell physiology J:132877
increased marginal zone B cell number J:132877
Cd19tm1(cre)Cgn/Cd19+
Traf3tm1Rbr/Traf3tm1Rbr

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal B cell physiology J:132877
increased follicular B cell number J:132877
increased marginal zone B cell number J:132877
lymph node hyperplasia J:132877
Cd19tm1(cre)Cgn/Cd19+
Ube2ntm1Aki/Ube2ntm1Aki

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:112287
abnormal humoral immune response J:112287
abnormal spleen marginal zone morphology J:112287
decreased B cell number J:112287
decreased B cell proliferation J:112287
decreased immunoglobulin level J:112287
decreased marginal zone B cell number J:112287
increased B cell apoptosis J:112287
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:27463
abnormal B cell physiology J:27463
abnormal immunoglobulin level J:27463
absent spleen germinal center J:83213, J:27463
decreased B-1 B cell number J:83213, J:27463
decreased IgE level J:27463
decreased IgG1 level J:27463
decreased IgM level J:27463
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn
Ightm1Mnz/Ightm1Mnz

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:75653
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn
Ightm2Mnz/Ightm2Mnz

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:75653
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn
Ptentm1Hwu/Ptentm1Hwu

(involves: 129P2/OlaHsd * 129S4/SvJae)
immune system phenotype J:83213
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:155314
immune system phenotype J:155314
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:155314
immune system phenotype J:155314
Cd19tm1(cre/ERT2)Rsky/Cd19+
Myd88em1.1Rsky/Myd88+

(involves: 129P2/OlaHsd * C57BL/6NTac)
increased IgM level J:308792
increased plasma cell number J:308792
Cd19tm1Tft/Cd19tm1Tft
(Not Specified)
abnormal B cell physiology J:27236
decreased B cell number J:27236
decreased B cell proliferation J:27236
decreased B-1 B cell number J:27236
decreased IgA level J:27236
decreased IgG1 level J:27236
decreased IgG2a level J:27236
decreased IgG2b level J:27236
decreased IgG3 level J:27236
decreased IgM level J:27236
Cd19tm1Tft/Cd19tm1Tft
(involves: 129/Sv * C57BL/6)
decreased neutrophil cell number J:66111
decreased tumor necrosis factor secretion J:66111
Cd19tm1Tft/Cd19tm1Tft
(involves: 129 * C57BL/6)
abnormal humoral immune response J:71174
decreased B cell number J:71174
decreased B cell proliferation J:71174
decreased B-1 B cell number J:71174
decreased IgA level J:71174
decreased IgG1 level J:71174
decreased IgG2b level J:71174
decreased IgM level J:71174
Cd19tm1Tft/Cd19tm1Tft
(B6.Cg-Cd19tm1Tft)
abnormal B cell physiology J:136210
decreased anti-double stranded DNA antibody level J:136210
decreased anti-nuclear antigen antibody level J:136210
decreased circulating interferon-gamma level J:136210
decreased circulating interleukin-4 level J:136210
decreased circulating interleukin-6 level J:136210
decreased circulating interleukin-10 level J:136210
decreased circulating tumor necrosis factor level J:136210
decreased IgA level J:136210
decreased IgG1 level J:136210
decreased IgG2a level J:136210
decreased IgG2b level J:136210
decreased IgG3 level J:136210
decreased IgM level J:136210
decreased interleukin-10 secretion J:106487
increased CD8-positive, alpha-beta T cell number J:106487
increased interferon-gamma secretion J:106487
increased susceptibility to experimental autoimmune encephalomyelitis J:106487
Cd19tm1Tft/Cd19tm1Tft
Lyntm1Sor/Lyntm1Sor

(involves: 129S4/SvJaeSor * C57BL/6)
abnormal humoral immune response J:71174
decreased anti-double stranded DNA antibody level J:71174
decreased B cell number J:71174
decreased B cell proliferation J:71174
decreased B-1 B cell number J:71174
decreased mature B cell number J:71174
decreased susceptibility to systemic lupus erythematosus J:71174
enlarged spleen J:71174
immune system phenotype J:71174
Cd22m1Anu/Cd22m1Anu
(C57BL/6JAnu-Cd22m1Anu/AnuApb)
arrested B cell differentiation J:104190
decreased B cell number J:104190
Cd22m1Btlr/Cd22m1Btlr
(C57BL/6J-Cd22m1Btlr)
abnormal B cell differentiation J:173079
abnormal humoral immune response J:173079
Cd22m1Btlr/Cd22m1Btlr
(involves: C57BL/6J)
abnormal B cell differentiation J:185495
decreased IgM level J:185495
immune system phenotype J:185495
Cd22m2Btlr/Cd22m2Btlr
(C57BL/6J-Cd22m2Btlr)
abnormal B cell differentiation J:215821
abnormal CD4-positive, alpha-beta T cell physiology J:215821
Cd22m3Btlr/Cd22m3Btlr
(C57BL/6J-Cd22m3Btlr)
decreased B cell number J:220066
increased B-1a cell number J:220066
Cd22m4Btlr/Cd22m4Btlr
(C57BL/6J-Cd22m4Btlr)
decreased B cell number J:224660
decreased B-2 B cell number J:224660
decreased memory B cell number J:224660
increased B-1a cell number J:224660
Cd22m5Btlr/Cd22m5Btlr
(C57BL/6J-Cd22m5Btlr)
decreased B cell number J:254827
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254827
increased CD8-positive, alpha-beta memory T cell number J:254827
Cd22tm1.1(CD22)Lnit/Cd22tm1.1(CD22)Lnit
(involves: 129S4/SvJae)
abnormal B cell physiology J:189017
decreased B cell number J:189017
decreased marginal zone B cell number J:189017
decreased transitional stage T1 B cell number J:189017
decreased transitional stage T2 B cell number J:189017
immune system phenotype J:189017
Cd22tm1b(EUCOMM)Wtsi/Cd22tm1b(EUCOMM)Wtsi
(C57BL/6N-Cd22tm1b(EUCOMM)Wtsi/Tcp)
increased monocyte cell number J:211773
Cd22tm1Eac/Cd22+
Lyntm1Ard/Lyn+
Ptpn6me-v/Ptpn6+
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
increased IgM level J:110531
Cd22tm1Eac/Cd22+
Lyntm1Ard/Lyn+
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
Cd22tm1Eac/Cd22+
Ptpn6me-v/Ptpn6+
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
Cd22tm1Eac/Cd22+
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mature B cell morphology J:110531
Cd22tm1Eac/Cd22tm1Eac
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell activation J:37451
abnormal B cell proliferation J:37451, J:132991
abnormal mature B cell morphology J:37451
abnormal transitional stage B cell morphology J:132991
decreased IgG1 level J:37451
decreased IgG3 level J:37451
decreased IgM level J:37451
decreased marginal zone B cell number J:132991
decreased mature B cell number J:37451, J:132991
decreased memory B cell number J:37451
increased B cell apoptosis J:132991
Cd22tm1Lam/Cd22tm1Lam
(involves: 129 * C57BL/6)
abnormal B cell activation J:125719
decreased marginal zone B cell number J:125719
decreased mature B cell number J:125719
Cd22tm1Lam/Cd22tm1Lam
Ightm1.2Rsky/Igh+

(involves: 129 * BALB/c * C57BL/6)
abnormal class switch recombination J:125719
Cd22tm1Lam/Cd22tm1Lam
Ightm1.2Rsky/Ightm1.2Rsky

(involves: 129 * BALB/c * C57BL/6)
abnormal B cell activation J:125719
decreased B-1a cell number J:125719
Cd22tm1Lnit/Cd22tm1Lnit
(involves: 129P2/OlaHsd * C57BL/6)
decreased marginal zone B cell number J:198790
immune system phenotype J:198790
Cd22tm1Msn/Cd22tm1Msn
(either: (involves: 129S/SvEv * BALB/c) or (involves: 129S/SvEv * C57BL/6J))
abnormal B cell activation J:76974
abnormal B cell physiology J:76974
abnormal immune system physiology J:76974
abnormal immunoglobulin level J:76974
abnormal mature B cell morphology J:76974
increased anti-double stranded DNA antibody level J:76974, J:76975
increased B-1 B cell number J:76974
increased IgG2a level J:76975
increased IgG level J:76975
increased IgM level J:76974
Cd22tm1Tft/Cd22tm1Tft
(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:92736
decreased marginal zone B cell number J:92736
decreased mature B cell number J:92736
increased B cell proliferation J:92736
Cd22tm2Lnit/Cd22tm2Lnit
(involves: 129P2/OlaHsd * C57BL/6)
absent mature B cells J:198790
autoimmune response J:198790
decreased marginal zone B cell number J:198790
immune system phenotype J:198790
Cd22tm2Tft/Cd22tm2Tft
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
decreased B cell number J:92736
decreased B cell proliferation J:92736
increased B cell proliferation J:92736
Cd22tm2Tft/Cd22tm2Tft
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal peripheral B cell anergy J:208364
decreased B cell number J:208364
decreased B cell proliferation J:208364
increased activation-induced B cell apoptosis J:208364
Cd22tm2Tft/Cd22tm2Tft
Endoutm1Tft/Endoutm1Tft

(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:208364
Cd22tm3Lnit/Cd22tm3Lnit
(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal B cell physiology J:198790
abnormal immune system morphology J:198790
abnormal immune system physiology J:198790
absent mature B cells J:198790
autoimmune response J:198790
decreased B cell number J:198790
decreased marginal zone B cell number J:198790
decreased transitional stage B cell number J:198790
immune system phenotype J:198790
increased B cell apoptosis J:198790
increased IgG1 level J:198790
Cd22tm3Tft/Cd22tm3Tft
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
decreased B cell number J:92736
decreased B cell proliferation J:92736
increased B cell proliferation J:92736
Cd24atm1Pjln/Cd24atm1Pjln
(C57BL/6-Cd24atm1Pjln)
abnormal B cell differentiation J:76695
abnormal spleen morphology J:76695
decreased immature B cell number J:76695
decreased pre-B cell number J:76695
immune system phenotype J:76695
increased susceptibility to parasitic infection J:76695
Cd27em1(IMPC)Ccpcz/Cd27em1(IMPC)Ccpcz
(C57BL/6NCrl-Cd27em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
Cd27tm1Jbo/Cd27tm1Jbo
(either: B6.129P2-CD27tm1Jbo or 129P2/OlaHsd-Tnfrsf7tm1Jbo)
abnormal CD4-positive, alpha-beta T cell physiology J:65516
abnormal cytotoxic T cell physiology J:65516
abnormal T cell physiology J:65516
Cd27tm1Jbo/Cd27tm1Jbo
(B6.129P2-Cd27tm1Jbo)
abnormal leukopoiesis J:97606
decreased regulatory T cell number J:198200
immune system phenotype J:198200
increased leukocyte cell number J:97606
increased T cell apoptosis J:198200
Cd27tm1Jbo/Cd27tm1Jbo
Tg(CD19-Tnfsf7)#Rvl/0

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:88620
Cd28tm1.1Huen/Cd28tm1.1Huen
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NTac)
abnormal regulatory T cell physiology J:191101
decreased regulatory T cell number J:191101
Cd28tm1a(EUCOMM)Hmgu/Cd28tm1a(EUCOMM)Hmgu
(C57BL/6N-Cd28tm1a(EUCOMM)Hmgu/H)
decreased T cell number J:165965
increased CD4-positive, alpha-beta T cell number J:165965
increased leukocyte cell number J:165965
Cd28tm1Jmg/Cd28tm1Jmg
(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6)
abnormal cytokine secretion J:124570
abnormal germinal center B cell physiology J:124570
abnormal lymphopoiesis J:124570
decreased immunoglobulin level J:124570
decreased interleukin-2 secretion J:124570
Cd28tm1Jmg/Cd28tm1Jmg
(B6.129X1-Cd28tm1Jmg)
decreased interleukin-2 secretion J:149888
decreased susceptibility to experimental autoimmune encephalomyelitis J:149888
increased susceptibility to type I hypersensitivity reaction J:149888
Cd28tm1Jmg/Cd28tm1Mak
(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6)
abnormal cytokine secretion J:124570
abnormal germinal center B cell physiology J:124570
abnormal lymphopoiesis J:124570
decreased immunoglobulin level J:124570
decreased interleukin-2 secretion J:124570
decreased T cell proliferation J:149888, J:124570
Cd28tm1Ltu/Cd28tm1Ltu
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased regulatory T cell number J:194503
decreased T cell proliferation J:194503
enlarged lymph nodes J:194503
enlarged spleen J:194503
increased activated T cell number J:194503
increased B cell number J:194503
increased susceptibility to autoimmune disorder J:194503
increased susceptibility to experimental autoimmune encephalomyelitis J:194503
skin inflammation J:194503
Cd28tm1Mak/Cd28+
Cd5tm1Cgn/Cd5tm1Cgn

(either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP))
abnormal T cell clonal deletion J:110925
Cd28tm1Mak/Cd28tm1Mak
(involves: 129S2/SvPas * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:14194
abnormal class switch recombination J:14194
decreased IgG1 level J:14194
decreased IgG2b level J:14194
decreased immunoglobulin level J:14194
decreased interleukin-2 secretion J:14194
decreased T cell proliferation J:14194
increased IgG2a level J:14194
Cd28tm1Mak/Cd28tm1Mak
(NOD.129S2-Cd28tm1Mak)
abnormal CD4-positive, alpha-beta T cell physiology J:61905
abnormal response to transplant J:61905
increased susceptibility to autoimmune diabetes J:93421
increased T cell proliferation J:93421
Cd28tm1Mak/Cd28tm1Mak
(involves: 129S2/SvPas)
abnormal class switch recombination J:123989
abnormal regulatory T cell physiology J:191101
decreased interferon-gamma secretion J:205441
decreased interleukin-2 secretion J:205441, J:130882
decreased regulatory T cell number J:191101, J:205441
decreased spleen germinal center number J:123989
decreased T cell proliferation J:205441, J:130882, J:123989
enlarged thymus J:205441
Cd28tm1Mak/Cd28tm1Mak
(involves: 129S2/SvPas * NOD)
abnormal T-helper 1 physiology J:35353
abnormal T-helper 2 physiology J:35353
decreased IgG2a level J:35353
decreased interleukin-2 secretion J:35353
decreased interleukin-4 secretion J:35353
decreased T cell proliferation J:35353
increased interferon-gamma secretion J:35353
increased susceptibility to autoimmune diabetes J:35353
Cd28tm1Mak/Cd28tm1Mak
(involves: 129S2/SvPas * C57BL/6)
abnormal NK cell physiology J:95353
decreased circulating interferon-gamma level J:95353
decreased circulating interleukin-4 level J:95353
decreased interleukin-2 secretion J:149888
decreased susceptibility to experimental autoimmune encephalomyelitis J:149888
decreased T cell proliferation J:149888
increased susceptibility to type I hypersensitivity reaction J:149888
increased T cell apoptosis J:149888
Cd28tm1Mak/Cd28tm1Mak
(B6.129S2-Cd28tm1Mak)
abnormal cytotoxic T cell physiology J:76373
Cd28tm1Mak/Cd28tm1Mak
(B6.129S2-Cd28tm1Mak/J)
brain inflammation J:57613
decreased susceptibility to experimental autoimmune encephalomyelitis J:57613
Cd28tm1Mak/Cd28tm1Mak
Cd5tm1Cgn/Cd5+

(either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP))
abnormal T cell clonal deletion J:110925
Cd28tm1Mak/Cd28tm1Mak
Cd5tm1Cgn/Cd5tm1Cgn

(either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP))
abnormal T cell clonal deletion J:110925
increased CD4-positive, alpha-beta T cell number J:110925
increased CD8-positive, alpha-beta T cell number J:110925
Cd28tm1Mak/Cd28tm1Mak
Cd40lgtm1Flv/Cd40lgtm1Flv

(NOD.Cg-Cd40lgtm1Flv Cd28tm1Mak)
decreased regulatory T cell number J:93421
increased susceptibility to autoimmune diabetes J:93421
insulitis J:93421
Cd28tm1Mak/Cd28tm1Mak
Ndfip1Gt(RRD002)Byg/Ndfip1Gt(RRD002)Byg

(involves: 129P2/OlaHsd * 129S2/SvPas)
esophageal inflammation J:205692
increased eosinophil cell number J:205692
increased interleukin-2 secretion J:205692
increased interleukin-4 secretion J:205692
Cd28tm1Mak/Cd28tm1Mak
Stat6tm1Gru/Stat6tm1Gru

(C.129S2(B6)-Cd28tm1Mak Stat6tm1Gru)
increased susceptibility to parasitic infection J:90987
Cd28tm1Mak/Cd28tm1Mak
Tg(Cd4-cre)1Cwi/?
Traf6tm2Ywc/Traf6tm2Ywc

(involves: 129S2/SvPas * C57BL/6 * DBA/2)
decreased interleukin-2 secretion J:130882
decreased T cell proliferation J:130882
increased activated T cell number J:130882
increased memory T cell number J:130882
Cd28tm1Mak/Cd28tm1Mak
Tg(H2-K-Cd86)7All/0

(involves: BALB/c * C57BL/6 * CBA)
abnormal T cell differentiation J:112266
Cd28tm1Mak/Cd28tm1Mak
Tg(TcrLCMV)327Sdz/0

(involves: 129S2/SvPas * C57BL/6 * DBA/2)
abnormal T cell anergy J:123989
decreased cytotoxic T cell cytolysis J:123989
decreased splenocyte proliferation J:123989
decreased T cell proliferation J:123989
Cd28tm1Mak/Cd28tm1Mak
Tnfsf9tm1Thw/Tnfsf9tm1Thw

(involves: 129 * 129S2/SvPas * C57BL/6)
abnormal cytotoxic T cell physiology J:76373
increased length of allograft survival J:76373
Cd28tm1Mak/Cd28tm1Mak
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
increased length of allograft survival J:77250
Cd28tm1Pjl/Cd28tm1Pjl
(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:83722
abnormal cytotoxic T cell physiology J:83722
abnormal immunoglobulin level J:83722
decreased IgG1 level J:83722
decreased IgG2a level J:83722
decreased IgM level J:83722
decreased interleukin-12 secretion J:83722
decreased susceptibility to type IV hypersensitivity reaction J:83722
increased splenocyte proliferation J:83722
Cd28tm1Pjl/Cd28tm1Pjl
Tg(DO11.10)10Dlo/0

(involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6)
abnormal T cell activation J:25536
abnormal T cell proliferation J:25536
abnormal thymocyte activation J:25536
decreased interleukin-2 secretion J:25536
Cd28tm1Pjl/Cd28tm1Pjl
Tg(H2-K-Cd86)27All/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased B cell number J:112475
Cd28tm1Pjl/Cd28tm1Pjl
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk

(either: B6.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk or C.Cg-Cd28tm1Pjl Tnfrsf9tm1Byk)
abnormal class switch recombination J:83722
abnormal cytotoxic T cell physiology J:83722
decreased IgG1 level J:83722
decreased IgG2a level J:83722
decreased IgM level J:83722
decreased interleukin-12 secretion J:83722
decreased splenocyte proliferation J:83722
decreased susceptibility to type IV hypersensitivity reaction J:83722
Cd28tm1Shr/Cd28tm1Shr
(involves: 129S4/SvJae * BALB/c * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:68642
decreased interleukin-2 secretion J:68642
decreased T cell proliferation J:68642
Cd28tm1Shr/Cd28tm1Shr
Ctla4tm1Shr/Ctla4+

(C.129S4-Cd28tm1Shr Ctla4tm1Shr)
abnormal CD8-positive, alpha beta T cell morphology J:125259
increased susceptibility to autoimmune disorder J:125259
Cd28tm1Shr/Cd28tm1Shr
Ctla4tm1Shr/Ctla4tm1Shr

(C.129S4-Cd28tm1Shr Ctla4tm1Shr)
abnormal interferon level J:68642
abnormal interleukin secretion J:68642
decreased CD4-positive, alpha-beta T cell number J:68642
decreased T cell proliferation J:68642
increased length of allograft survival J:68642
Cd33tm1Avrk/Cd33tm1Avrk
(involves: 129X1/SvJ * C57BL/6)
decreased inflammatory response J:83728
Cd34tm1Lal/Cd34tm1Lal
(involves: 129S2/SvPas)
decreased splenocyte number J:30621
Cd34tm1Szk/Cd34tm1Szk
(involves: 129P2/OlaHsd * C57BL/6J)
decreased eosinophil cell number J:32799
immune system phenotype J:32799
Cd36em1(IMPC)Mbp/Cd36em1(IMPC)Mbp
(C57BL/6N-Cd36em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cd36obl/Cd36obl
(C57BL/6-Cd36obl)
abnormal cell-mediated immunity J:96018
abnormal macrophage physiology J:96018
endophthalmitis J:96018
increased susceptibility to bacterial infection J:96018
Cd36tm1Frm/Cd36tm1Frm
(involves: 129S4/SvJae)
abnormal microglial cell physiology J:140907
Cd36tm1Frm/Cd36tm1Frm
(involves: 129S4/SvJae * C57BL/6J)
abnormal chemokine level J:80658
abnormal macrophage physiology J:80658
Cd36tm1Frm/Cd36tm1Frm
(B6.129S4-Cd36tm1Frm)
abnormal response to infection J:100140
decreased interleukin-6 secretion J:100140
decreased interleukin-12 secretion J:100140
decreased tumor necrosis factor secretion J:100140
impaired macrophage phagocytosis J:100140
increased susceptibility to bacterial infection induced morbidity/mortality J:100140
sepsis J:100140
Cd36tm1Mfe/Cd36tm1Mfe
(B6.129S1-Cd36tm1Mfe)
abnormal B cell morphology J:130897
abnormal plasma cell differentiation J:130897
decreased IgG1 level J:130897
decreased IgG2a level J:130897
decreased IgG2c level J:130897
decreased IgG level J:130897
decreased IgM level J:130897
decreased immunoglobulin level J:130897
increased transitional stage B cell number J:130897
Cd36tm1Mfe/Cd36tm1Mfe
(involves: 129S1/Sv)
abnormal macrophage chemotaxis J:89664
Cd37tm1Hor/Cd37tm1Hor
(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:63315
abnormal humoral immune response J:63315
abnormal lymph node germinal center morphology J:63315
decreased IgG1 level J:63315
decreased spleen germinal center number J:63315
decreased spleen germinal center size J:63315
immune system phenotype J:63315
Cd38em1(IMPC)Ccpcz/Cd38em1(IMPC)Ccpcz
(C57BL/6NCrl-Cd38em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased CD4-positive NK T cell number J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
decreased effector memory T-helper cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
decreased NK T cell number J:211773
decreased T-helper cell number J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased NK cell number J:211773
Cd38tm1Lnd/Cd38tm1Lnd
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal humoral immune response J:49170
Cd38tm1Lnd/Cd38tm1Lnd
(NOD.129P2(B6)-Cd38tm1Lnd/LtJ)
increased susceptibility to autoimmune diabetes J:108097
increased T cell apoptosis J:108097
insulitis J:108097
Cd40m1Btlr/Cd40m1Btlr
(C57BL/6J-Cd40m1Btlr)
impaired humoral immune response J:221482
Cd40m2Btlr/Cd40m2Btlr
(C57BL/6J-Cd40m2Btlr)
abnormal humoral immune response J:254828
decreased IgG level J:254828
Cd40tm1Arah/Cd40tm1Arah
(B6.129S1-Cd40tm1Arah)
abnormal immunoglobulin level J:120512
abnormal response to transplant J:120512
absent spleen germinal center J:120512
decreased IgE level J:120512
decreased IgG1 level J:120512
decreased IgG2b level J:120512
decreased IgG level J:120512
decreased IgM level J:120512
increased IgG3 level J:120512
increased IgM level J:120512
Cd40tm1Geha/Cd40tm1Geha
(involves: 129S4/SvJae * C57BL/6)
abnormal lymph node germinal center morphology J:82298
decreased IgA level J:82298
decreased IgG1 level J:82298
decreased IgG2a level J:82298
decreased IgG2b level J:82298
decreased spleen germinal center number J:82298
decreased spleen germinal center size J:82298
Cd40tm1Kik/Cd40+
Mir146tm1.1Lfl/Mir146tm1.1Lfl
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:266124
increased T follicular helper cell number J:266124
Cd40tm1Kik/Cd40tm1Kik
(B6.129P2-Cd40tm1Kik/J)
abnormal dendritic cell physiology J:86998
increased susceptibility to bacterial infection J:86998
Cd40tm1Kik/Cd40tm1Kik
(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:25007
absent spleen germinal center J:25007
decreased IgA level J:25007
decreased IgE level J:25007
decreased IgG1 level J:25007
decreased IgG2a level J:25007
decreased IgG2b level J:25007
decreased IgG3 level J:25007
decreased immunoglobulin level J:25007
decreased neutrophil cell number J:25007
decreased susceptibility to type II hypersensitivity reaction J:61673
immune system phenotype J:25007
Cd40tm1Kik/Cd40tm1Kik
(involves: 129P2/OlaHsd)
absent germinal center B cells J:190943
decreased B cell number J:190943
immune system phenotype J:173115
Cd40tm1Kik/Cd40tm1Kik
Ltbrtm1Mmat/Ltbrtm1Mmat

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal thymus epithelium morphology J:173115
abnormal thymus medulla morphology J:173115
immune system phenotype J:173115
Cd40tm1Kik/Cd40tm1Kik
Tg(Tnfsf13b)1Fma/?

(B6.Cg-Cd40tm1Kik Tg(Tnfsf13b)1Fma)
abnormal B cell activation J:113556
abnormal class switch recombination J:113556
absent spleen germinal center J:113556
glomerulonephritis J:113556
increased anti-double stranded DNA antibody level J:113556
increased marginal zone B cell number J:113556
Cd40tm1Kik/Cd40tm1Kik
Tnfsf11tm1Pngr/Tnfsf11tm1Pngr

(involves: 129P2/OlaHsd)
abnormal thymus epithelium morphology J:173115
Cd40tm1Kik/Cd40tm1Kik
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix

(involves: 129 * 129P2/OlaHsd * BALB/c)
abnormal B cell physiology J:138560
enlarged lymph nodes J:93923
enlarged spleen J:93923
immune system phenotype J:138560
increased follicular B cell number J:138560
increased marginal zone B cell number J:138560
increased transitional stage B cell number J:138560
Cd40lgm1Btlr/Y
(involves: C57BL/6J)
abnormal class switch recombination J:185495
decreased IgG level J:185495
immune system phenotype J:185495
Cd40lgm1Btlr/Cd40lgm1Btlr
(C57BL/6J-Cd40lgm1Btlr)
decreased IgG level J:162147
immune system phenotype J:162147
Cd40lgm1Btlr/Cd40lgm1Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
decreased IgG level J:185495
immune system phenotype J:185495
Cd40lgtm1Flv/Y
Faslpr/Faslpr

(involves: 129P2/OlaHsd * 129S2/SvPas * MRL)
decreased autoantibody level J:38492
decreased IgG level J:38492
decreased immunoglobulin level J:38492
Cd40lgtm1Flv/Y
Faslpr/Faslpr
Tcratm1Mjo/Tcratm1Mjo

(involves: 129P2/OlaHsd * 129S2/SvPas * MRL)
decreased autoantibody level J:38492
increased anti-double stranded DNA antibody level J:38492
Cd40lgtm1Flv/Cd40lgtm1Flv
(involves: 129S2/SvPas * C57BL/6)
abnormal adaptive immunity J:25010
abnormal class switch recombination J:25010
abnormal immune system morphology J:25010
abnormal immune system physiology J:25010
abnormal osteoclast differentiation J:120087
abnormal T cell differentiation J:25010
abnormal T-helper 2 physiology J:25010
absent spleen germinal center J:25010
decreased double-positive T cell number J:25010
decreased IgA level J:25010
decreased IgD level J:25010
decreased IgE level J:25010
decreased IgG1 level J:25010
decreased IgG3 level J:25010
decreased immunoglobulin level J:25010
increased CD4-positive, alpha-beta T cell number J:25010
Cd40lgtm1Flv/Cd40lgtm1Flv
(NOD.129S2-Cd40lgtm1Flv)
decreased regulatory T cell number J:93421
decreased susceptibility to autoimmune diabetes J:93421
Cd40lgtm1Flv/Cd40lgtm1Flv
Faslpr/Faslpr

(involves: 129P2/OlaHsd * 129S2/SvPas * MRL)
decreased autoantibody level J:38492
decreased IgG level J:38492
decreased immunoglobulin level J:38492
Cd40lgtm1Flv/Cd40lgtm1Flv
Faslpr/Faslpr
Tcratm1Mjo/Tcratm1Mjo

(involves: 129P2/OlaHsd * 129S2/SvPas * MRL)
decreased autoantibody level J:38492
increased anti-double stranded DNA antibody level J:38492
Cd40lgtm1Imx/Y
(involves: 129S2/SvPas * C57BL/6)
abnormal antigen presentation J:21137
abnormal class switch recombination J:21137
abnormal immune system organ morphology J:21137
abnormal immune system physiology J:21137
abnormal lymph node morphology J:21137
absent lymph node germinal center J:21137
absent spleen germinal center J:21137
decreased IgA level J:21137
decreased IgE level J:21137
decreased IgG1 level J:21137
decreased IgG2b level J:21137
decreased immunoglobulin level J:21137
immune system phenotype J:21137
lymph node hypoplasia J:21137
Cd40lgtm1Imx/Y
(B6.129S2-Cd40lgtm1Imx/J)
abnormal leukocyte adhesion J:108988
Cd40lgtm1Imx/Cd40lgtm1Imx
(involves: 129S2/SvPas * C57BL/6J * BALB/c)
abnormal T cell clonal deletion J:110925
Cd40lgtm1Imx/Cd40lgtm1Imx
(involves: 129S2/SvPas * C57BL/6)
increased susceptibility to prion infection J:115487
microgliosis J:115487
Cd40lgtm1Parl/Y
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca)
decreased IgM level J:213459
increased IgG1 level J:213459
Cd40lgtm1Parl/Y
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
immune system phenotype J:213459
Cd40lgtm1Parl/Y
Tg(Tek-cre)1Ywa/0

(involves: 129 * C57BL/6 * CD-1 * SJL)
decreased IgA level J:213459
decreased IgG1 level J:213459
decreased IgG2a level J:213459
decreased IgG3 level J:213459
decreased IgM level J:213459
Cd40lgtm1Parl/Cd40lgtm1Parl
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca)
decreased IgM level J:213459
increased IgG1 level J:213459
Cd40lgtm1Parl/Cd40lgtm1Parl
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
immune system phenotype J:213459
Cd40lgtm1Parl/Cd40lgtm1Parl
Tg(Tek-cre)1Ywa/0

(involves: 129 * C57BL/6 * CD-1 * SJL)
decreased IgA level J:213459
decreased IgG1 level J:213459
decreased IgG2a level J:213459
decreased IgG3 level J:213459
decreased IgM level J:213459
Cd44M1Btlr/Cd44M1Btlr
(C57BL/6J-Cd44M1Btlr)
decreased alpha-beta T cell number J:267483
decreased CD4-positive, alpha-beta T cell number J:267483
decreased CD8-positive, alpha-beta T cell number J:267483
decreased central memory CD4-positive, alpha-beta T cell number J:267483
decreased central memory CD8 positive, alpha-beta T cell number J:267483
decreased effector memory CD4-positive, alpha-beta T cell number J:267483
Cd44tm1.1Ugu/Cd44tm1.1Ugu
(involves: 129/Sv * C57BL/6)
abnormal T-helper 1 physiology J:62867
abnormal T-helper 2 physiology J:62867
immune system phenotype J:62867
Cd44tm1.1Ugu/Cd44tm1.1Ugu
(B6.129(Cg)-Cd44tm1.1Ugu)
decreased susceptibility to experimental autoimmune encephalomyelitis J:199279
Cd44tm1.1Ugu/Cd44tm1.1Ugu
(SJL.129(Cg)-Cd44tm1.1Ugu)
decreased susceptibility to experimental autoimmune encephalomyelitis J:199279
decreased T cell proliferation J:199279
Cd44tm1.1Ugu/Cd44tm1.1Ugu
Il10tm1Cgn/Il10tm1Cgn

(involves: 129/Sv * C57BL/6)
abnormal immune system physiology J:62867
Cd44tm1Hbg/Cd44+
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6)
ileum inflammation J:145626
Cd44tm1Hbg/Cd44tm1Hbg
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:68069
abnormal CD8-positive, alpha beta T cell morphology J:68069
abnormal leukocyte migration J:68069
abnormal neutrophil physiology J:94850
Cd44tm1Hbg/Cd44tm1Hbg
(involves: 129S1/Sv * 129X1/SvJ)
abnormal osteoclast differentiation J:101563
abnormal response to infection J:86947
increased acute inflammation J:131974
Cd44tm1Hbg/Cd44tm1Hbg
(B6.129-Cd44tm1Hbg)
decreased mast cell histamine storage J:146846
decreased mast cell number J:146846
Cd44tm1Hbg/Cd44tm1Hbg
Tg(TNF)197Gkl/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal osteoclast differentiation J:97992
abnormal osteoclast morphology J:97992
arthritis J:97992
increased circulating interleukin-1 level J:97992
increased circulating interleukin-6 level J:97992
increased interleukin-1 secretion J:97992
increased interleukin-6 secretion J:97992
increased osteoclast cell number J:97992
Cd44tm1Hbg/Cd44tm1Hbg
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:145626
Cd44tm1Mak/Cd44+
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal leukocyte migration J:99032
Cd44tm1Mak/Cd44tm1Mak
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal leukocyte migration J:99032
immune system phenotype J:72658
increased susceptibility to parasitic infection J:72658
Cd44tm1Mak/Cd44tm1Mak
(B6.129P2-Cd44tm1Mak)
abnormal circulating cytokine level J:69351
abnormal leukocyte migration J:108245
decreased activation-induced cell death of T cells J:69351
impaired macrophage phagocytosis J:111216
impaired natural killer cell mediated cytotoxicity J:110889
increased circulating interferon-gamma level J:69351
increased circulating interleukin-2 level J:69351
increased circulating tumor necrosis factor level J:69351
liver inflammation J:69351
lung inflammation J:111216, J:108245
Cd44tm1Mak/Cd44tm1Mak
(D1.129P2-Cd44tm1Mak)
increased susceptibility to induced arthritis J:95275
Cd44tm1Mak/Cd44tm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
abnormal chemokine secretion J:155691
abnormal circulating chemokine level J:155691
abnormal interleukin secretion J:155691
decreased acute inflammation J:114341
decreased circulating tumor necrosis factor level J:155691
increased interleukin-1 beta secretion J:155691
increased interleukin-6 secretion J:155691
increased interleukin-10 secretion J:155691
increased tumor necrosis factor secretion J:155691
peritoneal inflammation J:155691
Cd44tm1Mak/Cd44tm1Mak
Itgaltm1Mak/Itgaltm1Mak

(B6.129P2-Cd44tm1Mak Itgaltm1Mak)
impaired natural killer cell mediated cytotoxicity J:110889
Cd44tm1Ugu/Cd44tm1Ugu
(involves: 129/Sv * C57BL/6)
abnormal T-helper 1 physiology J:62867
abnormal T-helper 2 physiology J:62867
immune system phenotype J:62867
Cd44tm2.1Ugu/Cd44tm2.1Ugu
(B6.129-Cd44tm2.1Ugu)
decreased susceptibility to experimental autoimmune encephalomyelitis J:199279
decreased T cell proliferation J:199279
Cd44tm2Kmz/Cd44tm2Kmz
(DBA/1LacJ-Cd44tm2Kmz)
decreased susceptibility to induced arthritis J:74268
Cd44tm2Kmz/Cd44tm2Kmz
(involves: BALB/c * DBA/1)
abnormal CD4-positive, alpha-beta T cell physiology J:114317
abnormal leukocyte adhesion J:114317
decreased susceptibility to type IV hypersensitivity reaction J:114317
impaired leukocyte tethering or rolling J:114317
impaired neutrophil recruitment J:114317
Cd44tm2Kmz/Cd44tm2Kmz
Selltm2Hyn/Selltm2Hyn

(involves: 129S2/SvPas * BALB/c * DBA/1)
abnormal CD4-positive, alpha-beta T cell physiology J:114317
abnormal leukocyte adhesion J:114317
decreased susceptibility to type IV hypersensitivity reaction J:114317
impaired leukocyte tethering or rolling J:114317
impaired neutrophil recruitment J:114317
Cd47tm1Fpl/Cd47+
(B6.129S7-Cd47tm1Fpl)
increased susceptibility to bacterial infection induced morbidity/mortality J:36489
Cd47tm1Fpl/Cd47tm1Fpl
(involves: 129S7/SvEvBrd)
decreased T cell number J:36489
impaired neutrophil recruitment J:148196
Cd47tm1Fpl/Cd47tm1Fpl
(B6.129S7-Cd47tm1Fpl)
abnormal neutrophil physiology J:36489
decreased osteoclast cell number J:116609
impaired granulocyte bactericidal activity J:36489
impaired neutrophil chemotaxis J:36489
impaired neutrophil phagocytosis J:36489
increased susceptibility to bacterial infection J:36489
increased susceptibility to bacterial infection induced morbidity/mortality J:36489
Cd47tm1Fpl/Cd47tm1Fpl
(C.129S7-Cd47tm1Fpl)
decreased osteoclast cell number J:116609
Cd47tm1Fpl/Cd47tm1Fpl
(NOD.129S7-Cd47tm1Fpl)
abnormal spleen morphology J:76580
abnormal splenic cell ratio J:76580
enlarged spleen J:76580
Cd47tm1Fpl/Cd47tm1Fpl
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal cytokine level J:134866
abnormal osteoclast differentiation J:147367
abnormal tumor necrosis factor level J:134866
decreased leukocyte cell number J:134866
decreased neutrophil cell number J:134866
decreased susceptibility to bacterial infection induced morbidity/mortality J:134866
increased susceptibility to bacterial infection J:134866
Cd48tm1Rsr/Cd48tm1Rsr
(B6.129S4-Cd48tm1Rsr)
abnormal T cell activation J:53718
decreased T cell proliferation J:53718
increased CD4-positive, alpha-beta T cell number J:53718
Cd53tm1.1Nmg/Cd53tm1.1Nmg
(involves: C57BL/6J)
abnormal B cell physiology J:260065
Cd55tm1Mme/Cd55tm1Mme
(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to experimental autoimmune myasthenia gravis J:80116
Cd55tm1Song/Cd55tm1Song
(involves: 129S6/SvEvTac * C57BL/6)
abnormal complement pathway J:52968
immune system phenotype J:52968
impaired complement alternative pathway J:52968
impaired complement classical pathway J:52968
Cd55tm1Song/Cd55tm1Song
(involves: 129S6/SvEvTac)
abnormal complement pathway J:76578
Cd55tm1Song/Cd55tm1Song
(B6.129S6-Cd55tm1Song)
increased susceptibility to experimental autoimmune myasthenia gravis J:113567
Cd55tm1Song/Cd55tm1Song
Cd59atm1Bpm/Cd59atm1Bpm

(B6.129-Cd55tm1Song Cd59atm1Bpm)
abnormal complement pathway J:113567
increased susceptibility to experimental autoimmune myasthenia gravis J:113567
myositis J:113567
Cd59atm1Bpm/Cd59atm1Bpm
(involves: 129 * C57BL/6)
increased susceptibility to experimental autoimmune encephalomyelitis J:89014
Cd59atm1Bpm/Cd59atm1Bpm
(involves: 129)
abnormal complement pathway J:148367
increased macrophage cell number J:148367
increased susceptibility to induced arthritis J:146711
Cd59atm1Bpm/Cd59atm1Bpm
(B6.129-Cd59atm1Bpm)
abnormal CD4-positive, alpha-beta T cell physiology J:119703, J:123582
abnormal complement pathway J:92414
abnormal humoral immune response J:119703
decreased B cell proliferation J:119703
decreased IgG level J:119703
decreased plasma cell number J:119703
decreased susceptibility to Poxviridae infection J:122201
increased CD4-positive, alpha-beta T cell number J:123582
increased double-positive T cell number J:123582
increased neutrophil cell number J:123582
increased susceptibility to experimental autoimmune myasthenia gravis J:113567
increased susceptibility to Orthomyxoviridae infection J:123582
increased T cell proliferation J:122201
lung inflammation J:123582
myositis J:113567
Cd59atm1Bpm/Cd59atm1Bpm
(involves: 129 * BALB/c)
increased susceptibility to Orthomyxoviridae infection J:123582
Cd59atm1Song/Cd59atm1Song
(involves: 129S6/SvEvTac)
abnormal complement pathway J:76578
Cd59atm1Song/Cd59atm1Song
Cd55tm1Song/Cd55tm1Song

(involves: 129S6/SvEvTac * C57BL/6)
abnormal complement pathway J:76578
Cd68tm1Shnd/Cd68tm1Shnd
(either: B6.129-Cd68tm1Shnd or (involves: 129S1/Sv * 129X1/SvJ))
abnormal dendritic cell antigen presentation J:175275
Cd68tm1Xfen/Cd68tm1Xfen
(C57BL/6J-Cd68tm1Xfen)
abnormal osteoclast morphology J:178120
abnormal osteoclast physiology J:178120
Cd69tm1Fsm/Cd69tm1Fsm
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal B cell differentiation J:61329
abnormal humoral immune response J:61329
immune system phenotype J:61329
increased IgG2a level J:61329
increased IgM level J:61329
increased immature B cell number J:61329
increased pre-B cell number J:61329
Cd69tm1Naka/Cd69tm1Naka
(C.129P2-Cd69tm1Naka)
decreased susceptibility to induced arthritis J:84940
impaired neutrophil chemotaxis J:84940
impaired neutrophil recruitment J:84940
Cd69tm1Naka/Cd69tm1Naka
(B6.129P2-Cd69tm1Naka)
abnormal CD4-positive, alpha-beta T cell physiology J:184704
abnormal humoral immune response J:184704
abnormal memory T cell physiology J:184704
abnormal T cell physiology J:184704
decreased CD4-positive, alpha-beta T cell number J:184704
decreased interferon-gamma secretion J:184704
decreased tumor necrosis factor secretion J:184704
Cd70tm1(cre)Jbo/Cd70tm1(cre)Jbo
(B6.129P2-Cd70tm1(cre)Jbo)
decreased regulatory T cell number J:198200
immune system phenotype J:198200
Cd70tm1.1Jda/Cd70tm1.1Jda
(B6.Cg-Cd70tm1.1Jda)
abnormal CD8-positive, alpha-beta T cell physiology J:193042
abnormal immune system physiology J:193042
abnormal T cell physiology J:193042
decreased CD8-positive, alpha-beta T cell number J:193042
immune system phenotype J:193042
increased susceptibility to Riboviria infection J:193042
Cd72b/Cd72b
Faslpr/Faslpr

(involves: C57BL/6 * C57BL/6JJmsSlc * MRL/Mp)
abnormal B cell number J:204782
abnormal T cell number J:204782
autoimmune response J:204782
decreased anti-double stranded DNA antibody level J:204782
decreased anti-nuclear antigen antibody level J:204782
decreased IgG level J:204782
decreased spleen weight J:204782
decreased susceptibility to autoimmune disorder J:204782
Cd72c/Cd72c
(involves: C57BL/6 * MRL)
immune system phenotype J:204782
increased B cell proliferation J:204782
Cd72c/Cd72c
Faslpr/Faslpr

(involves: C57BL/6 * C57BL/6JJmsSlc * MRL/Mp)
abnormal B cell number J:204782
abnormal T cell number J:204782
autoimmune response J:204782
enlarged lymph nodes J:204782
increased anti-chromatin antibody level J:204782
increased anti-double stranded DNA antibody level J:204782
increased anti-single stranded DNA antibody level J:204782
increased IgG level J:204782
increased spleen weight J:204782
increased susceptibility to systemic lupus erythematosus J:204782
liver inflammation J:204782
lung inflammation J:204782
Cd72tm1Jrp/Cd72tm1Jrp
(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal B cell activation J:76990
abnormal B cell differentiation J:76990
abnormal B cell physiology J:76990
decreased B cell number J:76990
decreased B-2 B cell number J:76990
decreased follicular B cell number J:76990
decreased mature B cell number J:76990
increased B cell proliferation J:76990
increased B-1 B cell number J:76990
increased B-1a cell number J:76990
increased IgM level J:76990
increased immature B cell number J:76990
increased marginal zone B cell number J:76990
increased pre-B cell number J:76990
increased pro-B cell number J:76990
Cd72tm1Jrp/Cd72tm1Jrp
Tg(BCL2)22Wehi/0

(either: (involves: 129P2/OlaHsd * C57BL/6JWehi * SJL/JWehi) or (involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JWehi * SJL/JWehi))
abnormal B cell physiology J:76990
decreased mature B cell number J:76990
increased immature B cell number J:76990
Cd72tm1Tsub/Cd72tm1Tsub
(involves: C57BL/6J)
glomerulonephritis J:204782
immune system phenotype J:204782
increased anti-chromatin antibody level J:204782
increased anti-double stranded DNA antibody level J:204782
increased anti-single stranded DNA antibody level J:204782
increased B cell proliferation J:204782
increased spleen weight J:204782
lung inflammation J:204782
Cd72tm1Tsub/Cd72tm1Tsub
Faslpr/Faslpr

(involves: C57BL/6J * C57BL/6JJmsSlc * MRL/Mp)
abnormal B cell number J:204782
abnormal T cell number J:204782
autoimmune response J:204782
enlarged lymph nodes J:204782
glomerulonephritis J:204782
increased anti-chromatin antibody level J:204782
increased anti-double stranded DNA antibody level J:204782
increased anti-single stranded DNA antibody level J:204782
increased spleen weight J:204782
liver inflammation J:204782
lung inflammation J:204782
Cd74em1(IMPC)H/Cd74em1(IMPC)H
(C57BL/6N-Cd74em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Cd74tm1Doi/Cd74tm1Doi
(either: (involves: 129/Sv * B10.BR) or (involves: 129/Sv * C57BL/6))
abnormal antigen presentation J:4119
abnormal level of surface class II molecules J:45185
decreased CD4-positive, alpha-beta T cell number J:4119, J:45185
increased CD8-positive, alpha-beta T cell number J:4119
Cd74tm1Doi/Cd74tm1Doi
(involves: 129S2/SvPas)
abnormal dendritic cell antigen presentation J:151699
Cd74tm1Doi/Cd74tm1Doi
H2-DMatm1Doi/H2-DMatm1Doi

(involves: 129S2/SvPas * C57BL/6)
abnormal professional antigen presenting cell physiology J:42482
decreased CD4-positive, alpha-beta T cell number J:42482
increased CD8-positive, alpha-beta T cell number J:42482
Cd74tm1Doi/Cd74tm1Doi
Tap1tm1Arp/Tap1tm1Arp

(involves: 129S2/SvPas * C57BL/6)
abnormal T cell number J:113083
Cd74tm1Eae/Cd74tm1Eae
(involves: 129S2/SvPas)
abnormal level of surface class II molecules J:65917
decreased B cell proliferation J:113050, J:132865
decreased CD4-positive, alpha-beta T cell number J:113050
decreased IgM level J:113050
Cd74tm1Eae/Cd74tm1Eae
(B6.129S2-Cd74tm1Eae)
abnormal lymph node cell ratio J:112084
arrested B cell differentiation J:112084
Cd74tm1Liz/Cd74tm1Liz
(involves: 129S/SvEv * C57BL/6J)
abnormal antigen presentation J:72243
abnormal antigen presentation via MHC class II J:65918
abnormal level of surface class II molecules J:65918
decreased CD4-positive, alpha-beta T cell number J:65918
decreased interferon-gamma secretion J:72243
decreased susceptibility to experimental autoimmune encephalomyelitis J:72243
decreased T cell proliferation J:72243
defective assembly of class II molecules J:65918
Cd74tm1Liz/Cd74tm1Liz
(B6.129S-Cd74tm1Liz)
abnormal antigen presentation J:125654
abnormal antigen presentation via MHC class II J:28966
abnormal level of surface class II molecules J:28966
abnormal T-helper 1 physiology J:125654
decreased CD4-positive, alpha-beta T cell number J:28966
decreased susceptibility to experimental autoimmune encephalomyelitis J:125654
decreased susceptibility to type IV hypersensitivity reaction J:125654
decreased T cell proliferation J:28966
defective assembly of class II molecules J:28966
Cd74tm1Liz/Cd74tm1Liz
(involves: 129S/SvEv * C57BL/6)
abnormal antigen presentation via MHC class II J:111565
Cd74tm1Liz/Cd74tm1Liz
(involves: 129S/SvEv * BALB/cAn)
abnormal antigen presentation via MHC class II J:110927, J:113714
abnormal B cell differentiation J:110927
abnormal dendritic cell antigen presentation J:110927
abnormal professional antigen presenting cell physiology J:113714
decreased CD4-positive, alpha-beta T cell number J:110927, J:113714
increased immature B cell number J:110927
Cd74tm1Liz/Cd74tm1Liz
(involves: 129S/SvEv * BALB/c * C57BL)
abnormal antigen presentation via MHC class II J:110927
abnormal B cell differentiation J:110927
abnormal dendritic cell antigen presentation J:110927
abnormal T cell proliferation J:110927
increased immature B cell number J:110927
Cd74tm1Liz/Cd74tm1Liz
(involves: 129S/SvEv * C57BL * C57BL/10 * C57BR)
abnormal antigen presentation via MHC class II J:110927
abnormal B cell differentiation J:110927
abnormal dendritic cell antigen presentation J:110927
abnormal T cell proliferation J:110927
increased immature B cell number J:110927
Cd74tm1Liz/Cd74tm1Liz
(involves: 129S/SvEv)
abnormal positive T cell selection J:125548
Cd74tm1Liz/Cd74tm1Liz
(B6.129S-Cd74tm1Liz/J)
decreased B cell number J:194664
Cd74tm1Liz/Cd74tm1Liz
H2-DMatm1Liz/H2-DMatm1Liz

(involves: 129S/SvEv * BALB/c)
decreased CD4-positive, alpha-beta T cell number J:113714
Cd74tm1Liz/Cd74tm1Liz
H2-DMatm1Luc/H2-DMatm1Luc
Tg(CD74)AR194Ayr/?

(involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * DBA/2J)
abnormal antigen presentation via MHC class II J:88717
decreased CD4-positive, alpha-beta T cell number J:88717
Cd74tm1Liz/Cd74tm1Liz
H2-DMatm1Luc/H2-DMatm1Luc
Tg(CD74*)1Ayr/0

(involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * DBA/2J)
abnormal antigen presentation via MHC class II J:88717
decreased CD4-positive, alpha-beta T cell number J:88717
Cd74tm1Liz/Cd74tm1Liz
Sppl2atm1Basc/Sppl2atm1Basc

(B6.129-Sppl2atm1Basc Cd74tm1Liz)
decreased B cell number J:194664
decreased Peyer's patch number J:194664
immune system phenotype J:194664
Cd74tm1Liz/Cd74tm1Liz
Sppl2atm1Dgen/Sppl2atm1Dgen

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
decreased follicular B cell number J:194595
immune system phenotype J:194595
Cd74tm2Liz/Cd74tm1Liz
(involves: 129S/SvEv * C57BL/6)
abnormal antigen presentation via MHC class II J:28966
immune system phenotype J:28966
increased T cell proliferation J:28966
Cd74tm2Liz/Cd74tm2Liz
(involves: 129S/SvEv * C57BL/6)
decreased interleukin-2 secretion J:72243
increased susceptibility to experimental autoimmune encephalomyelitis J:72243
Cd74tm3Liz/Cd74tm3Liz
(involves: 129S/SvEv * C57BL/6)
abnormal antigen presentation via MHC class II J:82880
abnormal level of surface class II molecules J:82880
decreased interleukin-2 secretion J:72243
defective assembly of class II molecules J:82880
immune system phenotype J:82880
increased susceptibility to experimental autoimmune encephalomyelitis J:72243
Cd79am1Anu/Cd79am1Anu
(involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd)
absent pre-B cells J:104190
decreased IgG level J:104190
Cd79am1Anu/Cd79am1Anu
(C57BL/6-Cd79am1Anu)
absent pre-B cells J:171924
Cd79am1Anu/Cd79am1Anu
Rasgrp1m1Anu/Rasgrp1m1Anu

(involves: C57BL/6JSfdAnu * CBA/J)
immune system phenotype J:207898
Cd79am1Btlr/Cd79am1Btlr
(involves: C57BL/6J * C57BL/10J)
abnormal humoral immune response J:174338
decreased B cell number J:174338
decreased IgG level J:174338
decreased IgM level J:174338
Cd79am1Btlr/Cd79am1Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
decreased B cell number J:185495
decreased IgG level J:185495
decreased IgM level J:185495
Cd79am2Btlr/Cd79am2Btlr
(C57BL/6J-Cd79am2Btlr)
decreased B-1 B cell number J:254836
decreased IgM level J:254836
impaired humoral immune response J:254836
Cd79atm1(cre)Reth/Cd79a+
Commd3tm1.1Ksuz/Commd3tm1.1Ksuz

(involves: BALB/c * C57BL/6NSlc * SJL)
abnormal follicular B cell physiology J:278399
abnormal plasmablast number J:278399
abnormal spleen B cell follicle morphology J:278399
decreased follicular B cell number J:278399
decreased IgG1 level J:278399
decreased IgG2b level J:278399
decreased IgG2c level J:278399
decreased IgM level J:278399
decreased mature B cell number J:278399
decreased spleen germinal center number J:278399
immune system phenotype J:278399
Cd79atm1(cre)Reth/Cd79a+
Commd8tm1.1Ksuz/Commd8tm1.1Ksuz

(involves: BALB/c * C57BL/6NSlc * SJL)
abnormal follicular B cell physiology J:278399
abnormal plasmablast number J:278399
abnormal spleen B cell follicle morphology J:278399
decreased follicular B cell number J:278399
decreased IgG1 level J:278399
decreased IgG2b level J:278399
decreased IgG2c level J:278399
decreased IgG3 level J:278399
decreased IgM level J:278399
decreased mature B cell number J:278399
decreased spleen germinal center number J:278399
immune system phenotype J:278399
Cd79atm1(cre)Reth/Cd79a+
Ctnnbl1tm1.1Crad/Ctnnbl1tm1.1Crad

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL)
abnormal B cell proliferation J:232010
abnormal class switch recombination J:232010
decreased B cell proliferation J:232010
immune system phenotype J:232010
Cd79atm1(cre)Reth/Cd79a+
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(BCL2)22Wehi/0

(involves: BALB/c * C57BL/6JWehi * SJL/JWehi)
decreased B cell number J:135783
decreased mature B cell number J:135783
Cd79atm1(cre)Reth/Cd79a+
Dynll1tm1.1Jhh/Dynll1tm1.1Jhh

(B6.Cg-Dynll1tm1.1Jhh Cd79atm1(Cre)Reth)
abnormal B cell morphology J:230105
decreased immature B cell number J:230105
decreased mature B cell number J:230105
decreased pre-B cell number J:230105
Cd79atm1(cre)Reth/Cd79a+
Dynll1tm1.1Jhh/Dynll1tm1.1Jhh
Tg(IghMyc)22Bri/0

(B6.Cg-Dynll1tm1.1Jhh Cd79atm1(Cre)Reth Tg(IghMyc)22Bri)
decreased immature B cell number J:230105
Cd79atm1(cre)Reth/Cd79a+
Huwe1tm1.1Mak/Y

(B6.Cg-Cd79atm1(cre)Reth Huwe1tm1.1Mak)
abnormal B cell differentiation J:181705
abnormal class switch recombination J:181705
abnormal humoral immune response J:181705
absent B-1a cells J:181705
decreased B cell proliferation J:181705
decreased follicular B cell number J:181705
decreased IgA level J:181705
decreased IgG1 level J:181705
decreased IgG2a level J:181705
decreased IgG3 level J:181705
decreased IgM level J:181705
decreased marginal zone B cell number J:181705
decreased mature B cell number J:181705
decreased pre-B cell number J:181705
decreased transitional stage B cell number J:181705
increased B cell apoptosis J:181705
increased susceptibility to Riboviria infection J:181705
Cd79atm1(cre)Reth/Cd79a+
Huwe1tm1.1Mak/Y
Trp53tm1Brn/Trp53tm1Brn

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal class switch recombination J:181705
absent B-1a cells J:181705
decreased IgG1 level J:181705
decreased IgM level J:181705
immune system phenotype J:181705
Cd79atm1(cre)Reth/Cd79a+
Ikzf1tm3.1Mbu/Ikzf1tm3.1Mbu

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL)
abnormal B cell differentiation J:209928
abnormal B cell number J:209928
decreased pre-B cell number J:209928
increased pro-B cell number J:209928
Cd79atm1(cre)Reth/Cd79a+
Inpp5dtm1Rav/Inpp5dtm1Rav

(involves: 129 * BALB/c * C57BL/6)
increased anti-chromatin antibody level J:178833
increased anti-double stranded DNA antibody level J:178833
increased anti-nuclear antigen antibody level J:178833
increased anti-single stranded DNA antibody level J:178833
increased autoantibody level J:178833
increased IgG level J:178833
increased susceptibility to systemic lupus erythematosus J:178833
Cd79atm1(cre)Reth/Cd79a+
Nfkbiztm1.1Muta/Nfkbiztm1.1Muta

(involves: BALB/c * C57BL/6)
immune system phenotype J:194832
Cd79atm1(cre)Reth/Cd79a+
Nr4a1tm1Pcn/Nr4a1tm1Pcn

(involves: 129 * BALB/c)
increased B cell proliferation J:306652
Cd79atm1(cre)Reth/Cd79a+
Nr4a1tm1Pcn/Nr4a1tm1Pcn
Nr4a3em1Juz/Nr4a3em1Juz

(involves: 129 * BALB/c * C57BL/6)
decreased B cell apoptosis J:306652
immune system phenotype J:306652
increased B cell proliferation J:306652
Cd79atm1(cre)Reth/Cd79a+
Phf5atm1.1Oux/Phf5atm1.1Oux

(involves: BALB/c * C57BL/6J)
abnormal B cell physiology J:345807
abnormal B cell receptor editing J:345807
abnormal immunoglobulin heavy chain V(D)J recombination J:345807
decreased B cell number J:345807
decreased early pro-B cell number J:345807
decreased immature B cell number J:345807
decreased late pro-B cell number J:345807
decreased mature B cell number J:345807
decreased pre-B cell number J:345807
increased pre-pro B cell number J:345807
small spleen J:345807
Cd79atm1(cre)Reth/Cd79a+
Phf5atm1.1Oux/Phf5atm1.1Oux
Tg(IghelMD4)4Ccg/0

(involves: BALB/c * C57BL/6 * C57BL/6J)
abnormal B cell number J:345807
Cd79atm1(cre)Reth/Cd79a+
Slc39a10tm1.1Tfk/Slc39a10tm1.1Tfk

(involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J)
decreased B cell number J:213935
decreased IgA level J:213935
decreased IgE level J:213935
decreased IgG1 level J:213935
decreased IgG2b level J:213935
decreased IgG2c level J:213935
decreased IgG3 level J:213935
decreased IgM level J:213935
decreased immunoglobulin level J:213935
decreased pro-B cell number J:213935
spleen atrophy J:213935
Cd79atm1(cre)Reth/Cd79a+
Wastm1.1Ldn/Y

(involves: BALB/c * C57BL/6)
abnormal B cell physiology J:182528
decreased B cell number J:182528
decreased follicular B cell number J:182528
decreased marginal zone B cell number J:182528
decreased mature B cell number J:182528
increased anti-chromatin antibody level J:182528
increased anti-double stranded DNA antibody level J:182528
increased anti-single stranded DNA antibody level J:182528
increased autoantibody level J:182528
increased germinal center B cell number J:182528
increased IgM level J:182528
increased plasma cell number J:182528
Cd79atm1(cre)Reth/Cd79a+
Wastm1.1Ldn/Was+

(involves: BALB/c * C57BL/6)
abnormal B cell number J:182528
abnormal B cell proliferation J:182528
Cd79atm1(cre)Reth/Cd79a+
Wastm1.1Ldn/Wastm1.1Ldn

(involves: BALB/c * C57BL/6)
abnormal B cell physiology J:182528
decreased B cell number J:182528
decreased follicular B cell number J:182528
decreased marginal zone B cell number J:182528
decreased mature B cell number J:182528
increased anti-chromatin antibody level J:182528
increased anti-double stranded DNA antibody level J:182528
increased anti-single stranded DNA antibody level J:182528
increased autoantibody level J:182528
increased germinal center B cell number J:182528
increased IgM level J:182528
increased plasma cell number J:182528
Cd79atm1(cre)Reth/Cd79atm1(cre)Reth
Mzb1tm1.1Rug/Mzb1tm1.1Rug

(involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL)
abnormal B cell number J:211639
decreased pre-B cell number J:211639
increased late pro-B cell number J:211639
increased pro-B cell number J:211639
small spleen J:211639
Cd79atm1.1(BAP31N-EGFP)Pld/Cd79atm1.1(BAP31N-EGFP)Pld
(Not Specified)
abnormal immune system cell morphology J:75114
Cd79atm1.1Cgn/Cd79a+
Cd79btm1Gzmn/Cd79btm1Gzmn

(involves: 129P2/OlaHsd)
decreased B cell number J:179254
decreased pre-B cell number J:179254
increased pro-B cell number J:179254
Cd79atm1.1Cgn/Cd79atm1.1Cgn
(involves: 129P2/OlaHsd)
decreased B-1a cell number J:124400
Cd79atm1.1Cgn/Cd79atm1.1Cgn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell activation J:71100
decreased B-1 B cell number J:71100
decreased IgG1 level J:71100
decreased marginal zone B cell number J:71100
decreased mature B cell number J:71100
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm1Gzmn/Cd79b+

(involves: 129P2/OlaHsd)
decreased B cell number J:179254
decreased pre-B cell number J:179254
increased pro-B cell number J:179254
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm1Gzmn/Cd79btm1Gzmn

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:124400
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm1Gzmn/Cd79btm1Gzmn

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:179254
absent pre-B cells J:179254
decreased B cell number J:179254
increased pro-B cell number J:179254
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm2.1Mnz/Cd79btm2.1Mnz

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
absent mature B cells J:71100
arrested B cell differentiation J:71100
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm3Mnz/Cd79btm3Mnz

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
immune system phenotype J:128768
Cd79atm1.1Rsky/Cd79atm1.1Rsky
(involves: C57BL/6)
abnormal humoral immune response J:179254
decreased IgG2b level J:179254
decreased IgG2c level J:179254
decreased IgG3 level J:179254
decreased marginal zone B cell number J:179254
decreased mature B cell number J:179254
immune system phenotype J:179254
increased anti-single stranded DNA antibody level J:179254
increased IgG2b level J:179254
increased IgG2c level J:179254
increased immature B cell number J:179254
increased pre-B cell number J:179254
increased transitional stage B cell number J:179254
increased transitional stage T1 B cell number J:179254
increased transitional stage T2 B cell number J:179254
increased transitional stage T3 B cell number J:179254
Cd79atm2(cre/Esr1*)Reth/Cd79a+
Rag1tm1.1Sadu/Rag1tm1.1Sadu

(involves: BALB/c)
arrested B cell differentiation J:155473
Cd79atm2(cre/Esr1*)Reth/Cd79a+
Rag1tm1.1Sadu/Rag1tm1.1Sadu

(involves: BALB/c)
immune system phenotype J:155473
Cd79atm2Cgn/Cd79atm2Cgn
(involves: C57BL/6 * C.B-20)
decreased B cell number J:80885
decreased immunoglobulin level J:80885
decreased mature B cell number J:80885
Cd79atm2Cgn/Cd79atm2Cgn
(involves: C57BL/6)
decreased mature B cell number J:71100, J:66840
decreased pre-B cell number J:71100, J:66840
increased pro-B cell number J:66840
Cd79atm2Cgn/Cd79atm2Cgn
Cd79btm2.1Mnz/Cd79btm2.1Mnz

(involves: 129/Sv * C57BL/6)
arrested B cell differentiation J:66840
decreased transitional stage B cell number J:66840
Cd79atm2Pld/Cd79atm2Pld
(BALB/c-Cd79atm2Pld)
abnormal B cell differentiation J:87492
abnormal T cell differentiation J:87492
absent mature B cells J:87492
decreased double-positive T cell number J:87492
Cd79atm2Pld/Cd79atm2Pld
Cd79btm1Mnz/Cd79btm1Mnz

(involves: 129S1/Sv * BALB/c)
absent pre-B cells J:87492
Cd79atm3Cgn/Cd79atm3Cgn
Tg(Mx1-cre)1Cgn/?

(involves: C57BL/6 * CBA)
abnormal metallophilic macrophage morphology J:88620
abnormal spleen marginal zone macrophage morphology J:88620
abnormal spleen red pulp morphology J:88620
decreased B cell number J:88620
Cd79atm3Cgn/Cd79atm4.1Cgn
(involves: C57BL/6 * CBA)
immune system phenotype J:88620
Cd79atm4.1Cgn/Cd79atm4.1Cgn
(involves: C57BL/6)
abnormal B cell differentiation J:91091
Cd79atm4.1Cgn/Cd79atm4.1Cgn
Ightm1.2Rsky/Igh+

(involves: BALB/c * C57BL/6)
abnormal pro-B cell differentiation J:125719
Cd79atm4Cgn/Cd79atm4.1Cgn
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:91091
decreased IgD level J:91091
decreased IgM level J:91091
Cd79atm4Cgn/Cd79atm4.1Cgn
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
absent immature B cells J:91091
arrested B cell differentiation J:91091
decreased B cell number J:91091
decreased follicular B cell number J:91091
decreased marginal zone B cell number J:91091
Cd79atm5.1Cgn/Cd79a+
Ightm1.2Rsky/Igh+

(involves: 129 * BALB/c * C57BL/6)
abnormal class switch recombination J:125719
Cd79atm5.1Cgn/Cd79atm5.1Cgn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:91091
Cd79atm5.1Cgn/Cd79atm5.1Cgn
(involves: 129 * C57BL/6)
abnormal B cell morphology J:125719
decreased B-1a cell number J:125719
decreased immature B cell number J:125719
decreased mature B cell number J:125719
decreased pre-B cell number J:125719
decreased T cell number J:125719
increased pro-B cell number J:125719
Cd79atm5.1Cgn/Cd79atm5.1Cgn
Ightm1.2Rsky/Igh+

(involves: 129 * BALB/c * C57BL/6)
abnormal class switch recombination J:125719
Cd79atm5.1Cgn/Cd79atm5.1Cgn
Ightm1.2Rsky/Ightm1.2Rsky

(involves: 129 * BALB/c * C57BL/6)
abnormal B cell morphology J:125719
abnormal class switch recombination J:125719
decreased immature B cell number J:125719
decreased mature B cell number J:125719
decreased pre-B cell number J:125719
decreased T cell number J:125719
increased B-1b cell number J:125719
increased pro-B cell number J:125719
Cd79atm5Cgn/Cd79atm5.1Cgn
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:91091
Cd79atm5Cgn/Cd79atm5.1Cgn
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
absent immature B cells J:91091
arrested B cell differentiation J:91091
decreased B cell number J:91091
Cd79atm6Cgn/Cd79atm6Cgn
(involves: C57BL/6)
abnormal B cell number J:113407
abnormal B cell physiology J:113407
abnormal humoral immune response J:113407
abnormal immunoglobulin level J:113407
decreased B cell proliferation J:113407
decreased B-1a cell number J:113407
decreased IgG2a level J:113407
decreased IgG3 level J:113407
decreased IgM level J:113407
immune system phenotype J:113407
increased transitional stage B cell number J:113407
Cd79atm7Cgn/Cd79atm7Cgn
(involves: C57BL/6)
abnormal immune system physiology J:113407
Cd79bm1Btlr/Cd79bm1Btlr
(C57BL/6J-Cd79bm1Btlr)
decreased B cell number J:267537
decreased B-1 B cell number J:267537
decreased NK cell number J:267537
increased alpha-beta T cell number J:267537
increased CD4-positive, alpha-beta T cell number J:267537
increased CD8-positive, alpha-beta T cell number J:267537
Cd79bm1Ghost/Cd79bm1Ghost
(B10.Cg-Ptprca Cd79bm1Ghost H2a)
abnormal B cell differentiation J:157450
absent B cells J:157450
absent Peyer's patches J:157450
arrested B cell differentiation J:157450
decreased IgA level J:157450
decreased IgG level J:157450
Cd79bM2Btlr/Cd79bM2Btlr
(C57BL/6J-Cd79bM2Btlr)
abnormal lymphocyte morphology J:272863
decreased B cell number J:272863
decreased B-1 B cell number J:272863
Cd79btm1Gzmn/Cd79btm1Gzmn
(involves: 129/Sv * C57BL/6)
abnormal immune system physiology J:124400
decreased B-1a cell number J:124400
decreased IgG1 level J:124400
increased IgD level J:124400
increased IgM level J:124400
Cd79btm1Mnz/Cd79btm1Mnz
(involves: 129S1/Sv)
abnormal pro-B cell differentiation J:78601
abnormal pro-B cell morphology J:78601
arrested B cell differentiation J:78601
Cd79btm1Mnz/Cd79btm1Mnz
Tg(BCL2)22Wehi/0
Tg(IghelMD4)4Ccg/0
Tg(Rag2-Igb)1Mnz/0

(involves: 129S1/Sv * C57BL/6 * C57BL/6JWehi * SJL/JWehi)
arrested B cell differentiation J:78601
Cd79btm1Mnz/Cd79btm1Mnz
Tg(BCL2)22Wehi/0
Tg(Rag2-Igb)1Mnz/0

(involves: 129S1/Sv * C57BL/6JWehi * SJL/JWehi)
arrested B cell differentiation J:78601
Cd79btm1Mnz/Cd79btm1Mnz
Tg(IghelMD4)4Ccg/0
Tg(Rag2-Igb)1Mnz/0

(involves: 129S1/Sv * C57BL/6)
abnormal immature B cell morphology J:78601
arrested B cell differentiation J:78601
Cd79btm1Mnz/Cd79btm1Mnz
Tg(Rag2-Igb)1Mnz/0

(involves: 129S1/Sv)
abnormal pre-B cell morphology J:78601
arrested B cell differentiation J:78601
Cd79btm2.1Mnz/Cd79btm2.1Mnz
(involves: 129 * C57BL/6)
decreased mature B cell number J:71100
Cd79btm2.1Mnz/Cd79btm2.1Mnz
(involves: 129/Sv * C57BL/6)
abnormal B cell activation J:66840
arrested B cell differentiation J:66840
decreased mature B cell number J:66840
decreased pre-B cell number J:66840
decreased transitional stage B cell number J:66840
increased pro-B cell number J:66840
Cd79btm3Mnz/Cd79btm3Mnz
(involves: 129/Sv * C57BL/6)
abnormal B cell physiology J:128768
abnormal immature B cell morphology J:128768
abnormal immune system physiology J:128768
decreased B cell number J:128768
decreased B cell proliferation J:128768
decreased B-1a cell number J:128768
decreased immature B cell number J:128768
decreased mature B cell number J:128768
increased marginal zone B cell number J:128768
increased pro-B cell number J:128768
Cd80tm1Lbgn/Cd80tm1Lbgn
(C3.Cg-Cd80tm1Lbgn)
abnormal T cell physiology J:110947
Cd80tm1Shr/Cd80tm1Shr
(involves: 129S4/SvJae)
abnormal immunoglobulin level J:39089
decreased B cell proliferation J:74662
Cd80tm1Shr/Cd80tm1Shr
Cd86tm1Shr/Cd86tm1Shr

(B6.129S4-Cd80tm1Shr Cd86tm1Shr)
brain inflammation J:57613
decreased susceptibility to experimental autoimmune encephalomyelitis J:57613
decreased T cell proliferation J:57613
increased interferon-gamma secretion J:57613
increased tumor necrosis factor secretion J:57613
Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr

(involves: 129S4/SvJae)
abnormal lymph node B cell domain morphology J:39089
abnormal spleen morphology J:39089
abnormal T cell physiology J:57090
abnormal T cell proliferation J:57090
decreased IgG1 level J:39089
decreased IgG2a level J:39089
decreased IgG level J:39089
decreased regulatory T cell number J:205441, J:113109
increased IgG3 level J:39089
increased IgM level J:39089
increased susceptibility to autoimmune diabetes J:113109
Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr

(involves: 129S4/SvJae * NOD)
abnormal CD4-positive, alpha-beta T cell physiology J:61905
abnormal cytokine secretion J:61905
increased susceptibility to autoimmune diabetes J:61905
insulitis J:61905
Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr

(129.SJL-Cd86tm2Shr)
decreased interleukin-2 secretion J:78992
decreased susceptibility to experimental autoimmune encephalomyelitis J:78992
increased susceptibility to experimental autoimmune encephalomyelitis J:78992
Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr

(involves: 129S4/SvJae * C57BL/6J * SJL)
decreased susceptibility to experimental autoimmune encephalomyelitis J:78992
Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr

(involves: 129S4/SvJae * BALB/c)
abnormal T cell number J:112266
decreased double-positive T cell number J:112266
Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr
Ctla4tm1Shr/Ctla4tm1Shr

(involves: 129S4/SvJae * BALB/c)
abnormal cytokine secretion J:57090
abnormal T cell physiology J:57090
increased T cell proliferation J:57090
Cd80tm1Shr/Cd80tm1Shr
Cd86tm2Shr/Cd86tm2Shr
Tg(Ighm-Ctla4Ig/Cd80)1Jbs/0

(involves: 129S4/SvJae * FVB/N * NOD)
decreased regulatory T cell number J:113109
decreased susceptibility to autoimmune diabetes J:113109
insulitis J:113109
Cd81tm1Geha/Cd81tm1Geha
(involves: 129S4/SvJae * C57BL/6)
abnormal B cell morphology J:43975
decreased B-1 B cell number J:43975
decreased B-1a cell number J:43975
increased B cell proliferation J:43975
increased IgA level J:43975
increased IgG3 level J:43975
increased IgM level J:43975
Cd81tm1Lvy/Cd81tm1Lvy
(involves: 129S1/Sv * 129X1/SvJ)
abnormal B cell morphology J:40394
abnormal T-helper 2 physiology J:40394
decreased IgG1 level J:40394
decreased IgG level J:40394
decreased susceptibility to parasitic infection J:126000
Cd81tm1Lvy/Cd81tm1Lvy
(CByJ.129-Cd81tm1Lvy)
abnormal T-helper 2 physiology J:46171
decreased susceptibility to type I hypersensitivity reaction J:46171
Cd81tm1Lvy/Cd81tm1Lvy
(either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1)
abnormal microglial cell morphology J:79426
Cd81tm1Tmiy/Cd81tm1Tmiy
(involves: 129/Sv * C57BL/6)
abnormal B cell differentiation J:41830
abnormal immune system cell morphology J:41830
abnormal macrophage physiology J:83795
abnormal T cell proliferation J:41830
decreased B cell proliferation J:41830
decreased B-1 B cell number J:41830
increased B cell proliferation J:41830
Cd81tm1Tmiy/Cd81tm1Tmiy
Cd9tm1Mek/Cd9tm1Mek

(involves: 129/Sv * C57BL/6)
abnormal macrophage physiology J:83795
increased osteoclast cell number J:83795
Cd82tm1Kjbr/Cd82tm1Kjbr
(Not Specified)
abnormal cellular extravasation J:326451
abnormal macrophage differentiation J:326451
abnormal neutrophil physiology J:326451
impaired leukocyte tethering or rolling J:326451
increased macrophage cell number J:326451
increased neutrophil cell number J:326451
increased susceptibility to bacterial infection J:326451
Cd83anu/Cd83anu
(involves: C57BL/6JAnu * CBA/CaJAnu)
abnormal B cell morphology J:104190
abnormal dendritic cell morphology J:104190
decreased CD4-positive, alpha-beta T cell number J:104190
Cd83lcd4/Cd83lcd4
(involves: C57BL/6J)
abnormal CD4-positive T cell differentiation J:92721
abnormal CD4-positive, alpha-beta T cell physiology J:92721
decreased susceptibility to type IV hypersensitivity reaction J:92721
decreased T cell proliferation J:92721
Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
(involves: C57BL/6 * C57BL/6N)
decreased CD4-positive, alpha-beta T cell number J:236611
Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
H2-Ab1b-tm2Hpl/H2-Ab1b-tm2Hpl

(involves: 129S4/SvJae * C57BL/6 * C57BL/6N)
immune system phenotype J:236611
Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf1tm1.1Sish/Marchf1tm1.1Sish

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N)
decreased CD4-positive, alpha-beta T cell number J:236611
Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf8tm1.1Lkle/Marchf8tm1.1Lkle

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N)
immune system phenotype J:236611
Cd83tm1Tft/Cd83tm1Tft
(involves: 129S4/SvJae * C57BL/6)
abnormal CD4-positive T cell differentiation J:75700
abnormal humoral immune response J:75700
arrested T cell differentiation J:75700
decreased CD4-positive, alpha-beta T cell number J:75700
decreased IgA level J:75700
decreased IgG1 level J:75700
decreased IgG2a level J:75700
decreased IgG2b level J:75700
decreased IgG3 level J:75700
decreased IgM level J:75700
decreased susceptibility to type IV hypersensitivity reaction J:75700
Cd84tm1Pls/Cd84tm1Pls
(C57BL/6J-Cd84tm1Pls)
abnormal CD4-positive, alpha-beta T cell physiology J:157915
abnormal long lived plasma cell morphology J:157915
decreased CD4-positive, alpha-beta T cell number J:157915
decreased germinal center B cell number J:157915
decreased IgG level J:157915
decreased interleukin-21 secretion J:157915
decreased spleen germinal center size J:157915
Cd84tm1Pls/Cd84tm1Pls
Tg(TcraTcrb)425Cbn/?

(B6.Cg-Cd84tm1Pls Tg(TcraTcrb)425Cbn)
abnormal CD4-positive, alpha-beta T cell physiology J:157915
Cd86tm1Shr/Cd86tm1Shr
(NOD.129S4-Cd86tm1Shr)
abnormal T cell proliferation J:142046
decreased regulatory T cell number J:93421
decreased susceptibility to autoimmune diabetes J:71352
decreased T cell proliferation J:93421
increased autoantibody level J:142046
increased interferon-gamma secretion J:142046
increased susceptibility to autoimmune diabetes J:93421
Cd86tm1Shr/Cd86tm1Shr
(involves: 129S4/SvJae)
abnormal humoral immune response J:39089
absent spleen germinal center J:39089
decreased IgG level J:39089
Cd86tm1Shr/Cd86tm1Shr
(B6.129S4-Cd86tm1Shr)
decreased T cell proliferation J:57613
increased interferon-gamma secretion J:57613
Cd86tm1Shr/Cd86tm1Shr
Marchf1tm1.1Sish/Marchf1tm1.1Sish

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
decreased interleukin-12 secretion J:157516
decreased tumor necrosis factor secretion J:157516
Cd86tm2Shr/Cd86tm2Shr
Icostm1Flv/Icostm1Flv

(involves: 129S1/Sv * 129S4/SvJaeSor)
abnormal cytokine level J:112600
Cd93tm1Mbo/Cd93tm1Mbo
(either: 129/Sv or B6.129-Cd93tm1Mbo or (involves: 129/Sv * C57BL/6))
impaired macrophage phagocytosis J:88610
Cd96em1(IMPC)Wtsi/Cd96em1(IMPC)Wtsi
(C57BL/6N-Cd96em1(IMPC)Wtsi/WtsiOulu)
increased leukocyte cell number J:211773
Cd96tm1.1Mjs/Cd96tm1.1Mjs
(B6.129P2(Cg)-Cd96tm1.1Mjs)
abnormal NK cell physiology J:209990
immune system phenotype J:209990
increased inflammatory response J:209990
increased susceptibility to endotoxin shock J:209990
Cd99Gt(Ayu21-B6T44)Imeg/Cd99Gt(Ayu21-B6T44)Imeg
(involves: C57BL/6)
immune system phenotype J:207031
Cd99Gt(Ayu21-B6T44)Imeg/Cd99Gt(Ayu21-B6T44)Imeg
(involves: C57BL/6 * C57BL/6NSlc)
abnormal splenocyte physiology J:212222
Cd99l2tm1.1Dvst/Cd99l2tm1.1Dvst
Tg(Tek-cre)1Ywa/0

(involves: 129S6/SvEvTac * BALB/c * C57BL/6)
abnormal cellular extravasation J:193021
decreased susceptibility to type IV hypersensitivity reaction J:193021
Cd99l2tm1.2Dvst/Cd99l2tm1.2Dvst
(involves: 129S6/SvEvTac * BALB/c * C57BL/6)
abnormal cellular extravasation J:193021
Cd101tm1.1Dil/Cd101tm1.1Dil
(involves: BALB/cJ * C57BL/6 * C57BL/6NTac)
decreased granulocyte number J:175943
Cd109tm1Mat/Cd109tm1Mat
(involves: 129S6/SvEvTac * C57BL/6J)
skin inflammation J:188696
Cd151tm1Lka/Cd151tm1Lka
(C57BL/6-Cd151tm1Lka)
abnormal T cell proliferation J:91605
Cd151tm1Nki/Cd151tm1Nki
(involves: 129P2/OlaHsd * FVB/N)
tubulointerstitial nephritis J:114988
Cd160tm1Yxf/Cd160tm1Yxf
(C57BL/6-Cd160tm1Yxf)
decreased interferon-gamma secretion J:222131
Cd160tm1Yxf/Cd160tm1Yxf
Rag1tm1Mom/Rag1tm1Mom

(B6.Cg-Rag1tm1Mom Cd160tm1Yxf)
decreased interferon-gamma secretion J:222131
Cd163tm1(KOMP)Vlcg/Cd163tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal circulating cytokine level J:224919
abnormal macrophage chemotaxis J:224919
Cd163tm1(KOMP)Vlcg/Cd163tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
lung inflammation J:233977
Cd177tm1(KOMP)Vlcg/Cd177tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal neutrophil physiology J:225335
decreased monocyte cell number J:225335
decreased neutrophil cell number J:225335
immune system phenotype J:225335
Cd180tm1Kmiy/Cd180tm1Kmiy
(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:63145
decreased IgG2b level J:137066
decreased IgG3 level J:137066
Cd180tm1Kmiy/Cd180tm1Kmiy
(involves: 129P2/OlaHsd * C57BL/6 * NZB * NZW)
decreased IgG2a level J:137066
decreased IgG3 level J:137066
Cd180tm1Kmiy/Cd180tm1Kmiy
Faslpr/Faslpr

(MRL.Cg-Cd180tm1Kmiy Faslpr)
blood vessel inflammation J:137066
decreased B cell number J:137066
decreased CD8-positive, alpha-beta T cell number J:137066
decreased IgG2a level J:137066
decreased IgG3 level J:137066
enlarged lymph nodes J:137066
enlarged spleen J:137066
glomerulonephritis J:137066
increased anti-nuclear antigen antibody level J:137066
increased autoantibody level J:137066
increased double-negative T cell number J:137066
Cd200tm1Jods/Cd200tm1Jods
(C57BL/6-Cd200tm1Jods)
abnormal cytokine level J:95862
abnormal immune system organ morphology J:65982
abnormal immune system physiology J:65982
abnormal lymph node morphology J:65982
abnormal macrophage physiology J:65982
abnormal microglial cell morphology J:65982
abnormal microglial cell physiology J:65982
enlarged lymph nodes J:65982
increased macrophage cell number J:79906, J:65982
increased spleen red pulp amount J:65982
increased susceptibility to experimental autoimmune encephalomyelitis J:65982
increased susceptibility to experimental autoimmune uveoretinitis J:79906
increased susceptibility to induced arthritis J:65982
Cd200r1tm1.1Rmgo/Cd200r1tm1.1Rmgo
(C57BL/6-Cd200r1tm1.1Rmgo)
abnormal dendritic cell physiology J:134313
abnormal professional antigen presenting cell physiology J:135069
abnormal response to transplant J:135069
increased interleukin-12b secretion J:135069
increased tumor necrosis factor secretion J:135069
Cd200r1tm1.1Rmgo/Cd200r1tm1.1Rmgo
Tg(tetO/CMV-CD200)1Rmgo/Tg(tetO/CMV-CD200)1Rmgo

(involves: C57BL/6)
abnormal dendritic cell physiology J:134313
Cd200r1tm1Eakj/Cd200r1tm1Eakj
(Not Specified)
abnormal macrophage physiology J:326965
decreased interferon-beta secretion J:192198
decreased interleukin-1 beta secretion J:192198
decreased interleukin-6 secretion J:192198
decreased susceptibility to Herpesvirales infection J:192198
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:192198
Cd207tm1(Hbegf/EGFP)Bjec/Cd207+
(involves: C57BL/6 * SJL)
absent Langerhans cell J:137517
decreased dendritic cell number J:137452
decreased susceptibility to type IV hypersensitivity reaction J:137517
increased susceptibility to Orthomyxoviridae infection J:137452
Cd207tm1(Hbegf/EGFP)Bjec/Cd207+
(involves: C57BL/6)
abnormal type IV hypersensitivity reaction J:179630
Cd207tm1.1Cfg/Cd207tm1.1Cfg
(involves: C57BL/6)
abnormal Peyer's patch morphology J:217719
decreased IgA level J:217719
decreased IgG1 level J:217719
decreased IgG2a level J:217719
decreased IgG3 level J:217719
decreased IgM level J:217719
Cd207tm1Mal/Cd207tm1Mal
(B6.129S2-Cd207tm1Mal)
abnormal Langerhans cell morphology J:95147
Cd207tm2.1(cre)Bjec/Cd207+
(B6.Cg-CD207tm2.1(cre)Bjec)
immune system phenotype J:179630
Cd207tm2.1(cre)Bjec/Cd207+
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl

(involves: 129S4/SvJaeSor * C57BL/6)
abnormal type IV hypersensitivity reaction J:179630
decreased dendritic cell number J:179630
Cd207tm2.1Mal/Cd207tm3.1(HBEGF/EGFP)Mal
(involves: 129S2/SvPas)
abnormal Langerhans cell morphology J:99114
absent Langerhans cell J:99114
decreased Langerhans cell number J:99114
Cd209atm1.1Cfg/Cd209atm1.1Cfg
(involves: C57BL/6)
decreased IgG2b level J:217719
increased inflammatory response J:217719
increased lymphocyte cell number J:217719
increased mature B cell number J:217719
increased monocyte cell number J:217719
increased plasma cell number J:217719
increased spleen germinal center size J:217719
increased T cell proliferation J:217719
Cd209atm1.1Cfg/Cd209atm1.1Cfg
(B6.Cg-Cd209atm1.1Cfg/Mmucd)
immune system phenotype J:194602
Cd209atm1Olne/Cd209atm1Olne
(involves: C57BL/6 * C57BL/6J)
immune system phenotype J:153503
Cd209btm1.1Cfg/Cd209btm1.1Cfg
(involves: C57BL/6 * C57BL/6J)
immune system phenotype J:153503
Cd209btm1.1Cfg/Cd209btm1.1Cfg
(involves: C57BL/6)
decreased mature B cell number J:217719
impaired macrophage phagocytosis J:288225
increased eosinophil cell number J:288225
increased IgG2b level J:217719
increased IgG3 level J:217719
increased IgM level J:217719
increased macrophage cell number J:217719
increased susceptibility to bacterial infection J:288225
urinary bladder inflammation J:288225
Cd209btm1Anjm/Cd209btm1Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:94698
impaired macrophage phagocytosis J:94698
increased susceptibility to bacterial infection J:94698
increased susceptibility to bacterial infection induced morbidity/mortality J:94698
Cd209btm1Anjm/Cd209btm1Anjm
(B6.129P2-Cd209btm1Anjm)
decreased interleukin-1 beta secretion J:159646
decreased interleukin-18 secretion J:159646
decreased susceptibility to endotoxin shock J:159646
decreased susceptibility to induced colitis J:159646
increased susceptibility to bacterial infection induced morbidity/mortality J:94698
Cd209btm1Anjm/Cd209btm1Anjm
(involves: 129P2/OlaHsd * BALB/c)
immune system phenotype J:209808
Cd209btm1Anjm/Cd209btm1Anjm
(C.129P2-Cd209btm1Anjm)
immune system phenotype J:143766
Cd209dtm1.1Cfg/Cd209dtm1.1Cfg
(involves: C57BL/6 * C57BL/6J)
increased circulating tumor necrosis factor level J:153503
increased susceptibility to bacterial infection J:153503
Cd209dtm1.1Cfg/Cd209dtm1.1Cfg
(involves: C57BL/6)
increased B cell number J:217719
increased B cell proliferation J:217719
Cd226tm1.1Cln/Cd226tm1.1Cln
(B6.129P2-Cd226tm1.1Cln)
decreased inflammatory response J:209990
decreased T cell proliferation J:159749
impaired natural killer cell mediated cytotoxicity J:159749
Cd226tm1.1Cln/Cd226tm1.1Cln
Tg(TcraTcrb)1100Mjb/0

(B6.Cg-Cd226tm1.1Cln Tg(TcraTcrb)1100Mjb)
abnormal T cell activation J:159749
decreased cytotoxic T cell cytolysis J:159749
decreased interferon-gamma secretion J:159749
decreased T cell proliferation J:159749
Cd226tm1Shib/Cd226tm1Shib
(involves: BALB/c)
abnormal immune system physiology J:165704
decreased cytotoxic T cell cytolysis J:165704
impaired natural killer cell mediated cytotoxicity J:165704
Cd244aChip/Cd244a+
(C57BL/6J-Cd244aChip)
abnormal NK cell physiology J:196519
impaired natural killer cell mediated cytotoxicity J:196519
Cd244aChip/Cd244aChip
(C57BL/6J-Cd244aChip)
abnormal NK cell physiology J:196519
impaired natural killer cell mediated cytotoxicity J:196519
Cd244atm1Kmle/Cd244atm1Kmle
(involves: C57BL/6)
impaired natural killer cell mediated cytotoxicity J:166054
increased natural killer cell mediated cytotoxicity J:92740
Cd247m1Btlr/Cd247m1Btlr
(C57BL/6J-Cd247m1Btlr)
abnormal CD4-positive, alpha-beta T cell physiology J:158794
Cd247tm1Lov/Cd247tm1Lov
(involves: 129S4/SvJae)
abnormal single-positive T cell number J:14170
abnormal T-helper 1 cell morphology J:14170
abnormal T-helper 1 physiology J:46914
absent gamma-delta intraepithelial T cell J:46914
decreased CD4-positive, alpha-beta T cell number J:14170
decreased double-positive T cell number J:14170
decreased thymocyte number J:14170
Cd247tm1Lov/Cd247tm1Lov
Fcer1gtm1Rav/Fcer1gtm1Rav

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal effector T cell morphology J:46914
abnormal T cell activation J:46914
abnormal T-helper 1 physiology J:46914
absent gamma-delta intraepithelial T cell J:46914
decreased thymocyte number J:46914
impaired natural killer cell mediated cytotoxicity J:64764
Cd247tm1Lov/Cd247tm2.1Lov
(involves: 129S4/SvJae)
immune system phenotype J:192915
Cd247tm1Mal/Cd247tm1Mal
(either: C57BL/6-Cd247tm1Mal or (involves: BALB/c * C57BL/6))
abnormal intraepithelial T cell morphology J:15272
abnormal T cell differentiation J:15272
decreased CD4-positive, alpha-beta T cell number J:15272
decreased CD8-positive, alpha-beta T cell number J:15272
decreased double-positive T cell number J:15272
decreased single-positive T cell number J:15272
decreased thymocyte number J:15272
increased double-negative T cell number J:15272
Cd247tm1Mal/Cd247tm1Mal
(involves: C57BL/6)
abnormal double-negative T cell morphology J:112990, J:110847
abnormal T cell differentiation J:112990
abnormal T cell morphology J:110847
abnormal thymocyte activation J:110847
decreased double-positive T cell number J:110847
Cd247tm1Mal/Cd247tm1Mal
Lcktm1Mak/Lcktm1Mak

(involves: 129S2/SvPas * C57BL/6)
abnormal double-negative T cell morphology J:110847
abnormal T cell differentiation J:110847
abnormal T cell morphology J:110847
abnormal thymocyte activation J:110847
decreased double-positive T cell number J:110847
Cd247tm1Mhu/Cd247tm1Mhu
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal T cell differentiation J:15579
decreased CD4-positive, alpha-beta T cell number J:15579
decreased CD8-positive, alpha-beta T cell number J:15579
decreased double-positive T cell number J:15579
decreased splenocyte proliferation J:15579
decreased T cell proliferation J:15579
decreased thymocyte number J:15579
enlarged lymph nodes J:15579
enlarged spleen J:15579
enlarged thymus cortex J:15579
immune system phenotype J:15579
increased double-negative T cell number J:15579
small thymus J:15579
small thymus medulla J:15579
thymus hypoplasia J:15579
Cd247tm1Mhu/Cd247tm1Mhu
Fcer1gtm1Rav/Fcer1gtm1Rav

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
decreased uterine NK cell number J:100668
Cd247tm1Tks/Cd247tm1Tks
(involves: 129P2/OlaHsd * C57BL/6)
abnormal alpha-beta intraepithelial T cell morphology J:15271
abnormal T cell proliferation J:15271
decreased CD4-positive, alpha-beta T cell number J:15271
decreased CD8-positive, alpha-beta T cell number J:15271
decreased double-positive T cell number J:15271
decreased single-positive T cell number J:15271
decreased thymocyte number J:15271
small thymus medulla J:15271
Cd247tm1Tks/Cd247tm1Tks
(B6.129P2-Cd247tm1Tks)
abnormal NK cell morphology J:66403
abnormal NK cell physiology J:66403
decreased NK T cell number J:28282
increased interferon-gamma secretion J:66403
increased natural killer cell mediated cytotoxicity J:66403
Cd247tm2.1Lov/Cd247tm2.1Lov
(Not Specified)
abnormal gamma-delta T cell differentiation J:192915
abnormal NK T cell morphology J:192915
abnormal regulatory T cell physiology J:192915
abnormal T cell differentiation J:192915
abnormal T cell physiology J:192915
abnormal T-helper 1 cell differentiation J:192915
decreased CD4-positive, alpha-beta T cell number J:192915
decreased CD8-positive, alpha-beta T cell number J:192915
decreased thymocyte apoptosis J:192915
decreased thymocyte number J:192915
immune system phenotype J:192915
increased regulatory T cell number J:192915
Cd247tm2.1Lov/Cd247tm2.1Lov
(B6.Cg-Cd247tm2.1Lov)
increased susceptibility to experimental autoimmune encephalomyelitis J:192915
Cd247tm2.1Lov/Cd247tm2.1Lov
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C57BL/6J * DBA/2J)
abnormal T cell differentiation J:192915
Cd248tm1Huso/Cd248tm1Huso
(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:107172
Cd274tm1.1Lex/Cd274tm1.1Lex
(involves: 129S5/SvEvBrd)
abnormal cytokine secretion J:126829
decreased CD8-positive, alpha-beta T cell number J:126829
increased susceptibility to experimental autoimmune encephalomyelitis J:126829
Cd274tm1Igu/Cd274tm1Igu
Vsirtm1Lex/Vsirtm1Lex

(involves: 129S5/SvEvBrd * C57BL/6)
abnormal T cell activation J:222944
Cd274tm1Lpc/Cd274tm1Lpc
(B6.129S-Cd274tm1Lpc)
abnormal CD8-positive, alpha-beta T cell physiology J:89781
decreased T cell apoptosis J:89781
increased activated T cell number J:89781
increased CD8-positive, alpha-beta T cell number J:89781
increased susceptibility to autoimmune disorder J:89781
Cd274tm1Lpc/Cd274tm1Lpc
(involves: 129S/SvEv)
abnormal chemokine secretion J:158023
increased tumor necrosis factor secretion J:158023
Cd274tm1Lpc/Cd274tm1Lpc
(involves: 129S/SvEv * C57BL/6)
abnormal dendritic cell physiology J:152305
abnormal T cell morphology J:136330
abnormal T-helper 1 cell differentiation J:162539
decreased susceptibility to Riboviria infection J:136330
decreased susceptibility to Riboviria infection induced morbidity/mortality J:136330
decreased T cell apoptosis J:136330
decreased T helper 1 cell number J:162539
increased CD8-positive, alpha-beta T cell number J:152305
increased IgG1 level J:162539
increased IgG2c level J:162539
increased susceptibility to bacterial infection J:162539
increased susceptibility to bacterial infection induced morbidity/mortality J:162539
increased susceptibility to experimental autoimmune encephalomyelitis J:142815
increased T cell number J:142815
Cd274tm1Lpc/Cd274tm1Lpc
(C.129S-Cd274tm1Lpc)
abnormal regulatory T cell physiology J:165841
abnormal T follicular helper cell physiology J:165841
decreased germinal center B cell number J:165841
decreased IgG1 level J:165841
decreased IgG2a level J:165841
decreased interleukin-17 secretion J:165841
decreased plasma cell number J:165841
decreased T-helper 17 cell number J:165841
immune system phenotype J:165841
increased interferon-gamma secretion J:165841
increased interleukin-4 secretion J:165841
increased susceptibility to induced arthritis J:165841
increased T cell proliferation J:165841
Cd274tm1Shr/Cd274tm1Shr
(involves: C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:91480
abnormal CD8-positive, alpha beta T cell morphology J:91480
Cd274tm1Shr/Cd274tm1Shr
(C.B6-Cd274tm1Shr)
abnormal interleukin secretion J:123785
increased interferon-gamma secretion J:123785
increased susceptibility to autoimmune diabetes J:123785
Cd274tm1Shr/Cd274tm1Shr
Pdcd1lg2tm3Shr/Pdcd1lg2tm3Shr

(C.B6-Cd274tm1Shr Pdcd1lg2tm3Shr)
abnormal dendritic cell physiology J:123785
decreased interleukin-4 secretion J:123785
increased interferon-gamma secretion J:123785
increased interleukin-2 secretion J:123785
Cd274tm1Shr/Cd274tm1Shr
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6)
increased susceptibility to autoimmune diabetes J:153040
Cd274tm2Shr/Cd274tm2Shr
(involves: 129/Sv * 129S4/SvJae)
abnormal cytokine secretion J:113851
decreased susceptibility to parasitic infection J:113851
Cd274tm2Shr/Cd274tm2Shr
Pdcd1lg2tm4Shr/Pdcd1lg2tm4Shr

(involves: 129S4/SvJae)
abnormal immune system physiology J:160970
Cd276tm1Lpc/Cd276tm1Lpc
(B6.129-Cd276tm1Lpc)
abnormal T-helper 1 physiology J:237700
abnormal T-helper 2 physiology J:237700
decreased susceptibility to experimental autoimmune encephalomyelitis J:237700
increased susceptibility to type I hypersensitivity reaction J:237700
Cd276tm1Lpc/Cd276tm1Lpc
(D1J.129-Cd276tm1Lpc)
abnormal T-helper 1 physiology J:237700
abnormal T-helper 17 cell physiology J:237700
decreased susceptibility to induced arthritis J:237700
Cd276tm1Mak/Cd276tm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T-helper 1 physiology J:84973
immune system phenotype J:84973
increased anti-single stranded DNA antibody level J:84973
increased inflammatory response J:84973
increased susceptibility to experimental autoimmune encephalomyelitis J:84973
increased T cell proliferation J:84973
Cd276tm1Mak/Cd276tm1Mak
(C.129P2-Cd276tm1Mak)
abnormal T-helper 1 physiology J:84973
increased inflammatory response J:84973
increased interferon-gamma secretion J:84973
Cd276tm1Wwh/Cd276tm1Wwh
(B6.Cg-B7h3tm1Wwh)
abnormal cytokine secretion J:95550
abnormal response to transplant J:95550
Cd300atm1b(EUCOMM)Hmgu/Cd300atm1b(EUCOMM)Hmgu
(C57BL/6N-Cd300atm1b(EUCOMM)Hmgu/Bay)
decreased eosinophil cell number J:211773
Cd300atm1Shib/Cd300atm1Shib
(B6JJcl.C-Cd300atm1Shib)
abnormal chemokine secretion J:189144
abnormal mast cell physiology J:189144
increased interleukin-10 secretion J:189144
increased interleukin-13 secretion J:189144
increased neutrophil cell number J:189144
increased tumor necrosis factor secretion J:189144
Cd300c2tm1Shib/Cd300c2tm1Shib
(B6.Cg-Cd300c2tm1Shib)
increased B cell proliferation J:177613
Cd300cem1(IMPC)Wtsi/Cd300cem1(IMPC)Wtsi
(C57BL/6N-Cd300cem1(IMPC)Wtsi/WtsiOulu)
increased leukocyte cell number J:211773
Cd300lbtm1Toki/Cd300lbtm1Toki
(B6.Cg-Cd300lbtm1Toki)
immune system phenotype J:163402
Cd300lftm1Gne/Cd300lftm1Gne
(involves: C57BL/6N)
immune system phenotype J:156819
increased interleukin-1 alpha secretion J:156819
increased interleukin-1 beta secretion J:156819
increased interleukin-12 secretion J:156819
increased susceptibility to experimental autoimmune encephalomyelitis J:156819
Cd300lftm1Toki/Cd300lftm1Toki
(Not Specified)
abnormal interleukin secretion J:190979
abnormal mast cell physiology J:190979
immune system phenotype J:190979
increased interleukin-4 secretion J:190979
increased interleukin-5 secretion J:190979
increased interleukin-13 secretion J:190979
increased susceptibility to type I hypersensitivity reaction J:190979
respiratory system inflammation J:190979
Cd302tm1.1Dnjh/Cd302tm1.1Dnjh
(involves: C57BL/6)
abnormal CD8-positive, alpha-beta T cell physiology J:301848
abnormal dendritic cell physiology J:301848
decreased dendritic cell number J:301848
immune system phenotype J:301848
Cd320Gt(CC0426)Wtsi/Cd320Gt(CC0426)Wtsi
(involves: 129P2/OlaHsd * C57BL/6)
decreased leukocyte cell number J:199961
Cdc7tm1.1(KOMP)Vlcg/Cdc7+
(C57BL/6N-Cdc7tm1.1(KOMP)Vlcg/Tcp)
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Cdc7tm1Hmas/Cdc7tm1Hmas
Tg(EF1A-Cdc7)DKO28Hmas/0

(involves: 129S/Sv * C57BL/6)
immune system phenotype J:85942
Cdc42ep5tm1(KOMP)Wtsi/Cdc42ep5tm1(KOMP)Wtsi
(C57BL/6N-Cdc42ep5tm1(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Cdc73tm1Btt/Cdc73tm1Btt
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
small spleen J:135255
Cdca7lem1(IMPC)Mbp/Cdca7lem1(IMPC)Mbp
(C57BL/6NCrl-Cdca7lem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Cdcp2em1(IMPC)Mbp/Cdcp2em1(IMPC)Mbp
(C57BL/6N-Cdcp2em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Cdcs1C3H/HeJBir/Cdcs1C3H/HeJBir
(involves: B6.129P2-Il10tm1Cgn/Lt * C3Bir.129P2(B6)-Il10tm1Cgn/Lt)
abnormal immune system physiology J:72978
Cdcs1C3H/HeJBir/Cdcs1C57BL/6J
(involves: C3H/HeJBir-Il10tm1Cgn * C57BL/6J-Il10tm1Cgn)
colitis J:72978
Cdcs2C3H/HeJBir/Cdcs2C3H/HeJBir
(involves: B6.129P2-Il10tm1Cgn/Lt * C3Bir.129P2(B6)-Il10tm1Cgn/Lt)
intestinal inflammation J:72978
Cdcs2C3H/HeJBir/Cdcs2C57BL/6J
(involves: B6.129P2-Il10tm1Cgn/Lt * C3Bir.129P2(B6)-Il10tm1Cgn/Lt)
intestinal inflammation J:72978
Cdcs3C3H/HeJBir/Cdcs3C3H/HeJBir
(involves: B6.129P2-Il10tm1Cgn/Lt * C3Bir.129P2(B6)-Il10tm1Cgn/Lt)
intestinal inflammation J:72978
Cdcs4C3H/HeJBir/Cdcs4C57BL/6J
(involves: C3H/HeJBir * C57BL/6J)
intestinal inflammation J:72978
Cdcs4C57BL/6J/Cdcs4C57BL/6J
(involves: C3H/HeJBir * C57BL/6J)
intestinal inflammation J:72978
Cdcs5C57BL/6J/Cdcs5C57BL/6J
(involves: C3H/HeJBir * C57BL/6J)
intestinal inflammation J:72978
Cdcs6C57BL/6J/?
(involves: B6.129P2-Il10tm1Cgn/Lt * C3Bir.129P2(B6)-Il10tm1Cgn/Lt)
intestinal inflammation J:72978
Cdcs7C3H/HeJBir/Cdcs7C3H/HeJBir
(involves: C3H/HeJBir * C57BL/6J)
intestinal inflammation J:78917
Cdcs8C57BL/6J/Cdcs8C57BL/6J
(involves: C3H/HeJBir * C57BL/6J)
intestinal inflammation J:78917
Cdcs9C3H/HeJBir/Cdcs9C3H/HeJBir
(involves: C3H/HeJBir * C57BL/6J)
intestinal inflammation J:78917
Cdcs9C3H/HeJBir/Cdcs9C57BL/6J
(involves: C3H/HeJBir * C57BL/6J)
intestinal inflammation J:78917
Cdcs10C3H/HeJBir/Cdcs10C3H/HeJBir
(involves: C3H/HeJBir-Il10tm1Cgn * C57BL/6J-Il10tm1Cgn)
intestinal inflammation J:78917
Cdcs10C3H/HeJBir/Cdcs10C57BL/6J
(involves: C3H/HeJBir-Il10tm1Cgn * C57BL/6J-Il10tm1Cgn)
intestinal inflammation J:72978
Cdh1tm1Mlec/Cdh1tm1Mlec
(involves: 129S2/SvPas)
increased susceptibility to bacterial infection J:142843
Cdh5tm3(Cdh5/Ctnna1)Dvst/Cdh5tm3(Cdh5/Ctnna1)Dvst
(involves: 129 * C57BL/6)
abnormal cellular extravasation J:177191
abnormal leukocyte migration J:177191
abnormal lymphatic vessel endothelial cell morphology J:213676
immune system phenotype J:213676
increased leukocyte cell number J:177191
increased neutrophil cell number J:177191
Cdh5tm3(Cdh5/Ctnna1)Dvst/Cdh5tm3(Cdh5/Ctnna1)Dvst
(B6.Cg-Cdh5tm3(Cdh5/Ctnna1)Dvst)
abnormal lymphatic vessel endothelium morphology J:213676
abnormal lymphatic vessel morphology J:213676
Cdh5tm4(Cdh5/Fkbp,Ptprb/Mtor*)Dvst/Cdh5tm4(Cdh5/Fkbp,Ptprb/Mtor*)Dvst
(involves: C57BL/6)
abnormal cellular extravasation J:178759
impaired neutrophil recruitment J:178759
Cdh5tm5Dvst/Cdh5tm5Dvst
(B6.Cg-Cdh5tm5Dvst)
abnormal cellular extravasation J:209801
Cdh5tm6Dvst/Cdh5tm6Dvst
(B6.Cg-Cdh5tm6Dvst)
abnormal cellular extravasation J:209801
Cdh10tm2b(KOMP)Wtsi/Cdh10tm2b(KOMP)Wtsi
(C57BL/6N-Cdh10tm2b(KOMP)Wtsi/Ucd)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Cdh11em1(IMPC)Mbp/Cdh11em1(IMPC)Mbp
(C57BL/6N-Cdh11em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cdh17M1Btlr/Cdh17M1Btlr
(C57BL/6J-Cdh17M1Btlr)
increased susceptibility to induced colitis J:272090
Cdh17tm1Ohn/Cdh17tm1Ohn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen marginal zone morphology J:96738
decreased B cell number J:96738
decreased B-1a cell number J:96738
decreased germinal center B cell number J:96738
decreased IgG level J:96738
decreased marginal zone B cell number J:96738
decreased mature B cell number J:96738
decreased spleen germinal center size J:96738
increased pre-B cell number J:96738
increased pro-B cell number J:96738
Cdh23tm2b(EUCOMM)Wtsi/Cdh23tm2b(EUCOMM)Wtsi
(C57BL/6N-Cdh23tm2b(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Cdk2tm2Sgo/Cdk2tm2Sgo
Cdk4tm2.1Bbd/Cdk4tm2.1Bbd
Polr2atm1(cre/ERT2)Bbd/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
increased susceptibility to autoimmune diabetes J:125217
Cdk4+/Cdk4+
Tg(Mt1-Hgf)#Lmb/0

(B6.Cg-Cdk4tm1.1Bbd Tg(Mt1-Hgf)#Lmb)
abnormal axillary lymph node morphology J:111992
abnormal inguinal lymph node morphology J:111992
Cdk4tm1.1Bbd/Cdk4+
Tg(Mt1-Hgf)#Lmb/0

(B6.Cg-Cdk4tm1.1Bbd Tg(Mt1-Hgf)#Lmb)
abnormal axillary lymph node morphology J:111992
abnormal inguinal lymph node morphology J:111992
enlarged axillary lymph nodes J:111992
enlarged inguinal lymph nodes J:111992
Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Tg(Mt1-Hgf)#Lmb/0

(B6.Cg-Cdk4tm1.1Bbd Tg(Mt1-Hgf)#Lmb)
abnormal axillary lymph node morphology J:111992
abnormal inguinal lymph node morphology J:111992
enlarged axillary lymph nodes J:111992
enlarged inguinal lymph nodes J:111992
Cdk4tm1Kiyo/Cdk4+
Lin9tm1Orc/Lin9+

(involves: 129S1/Sv)
decreased susceptibility to autoimmune diabetes J:111333
Cdk5rap2an/Cdk5rap2an
(Not Specified)
decreased leukocyte cell number J:5439
Cdk5rap2Gt(RRO242)Byg/Cdk5rap2+
(involves: 129P2/OlaHsd * C57BL/6J)
decreased leukocyte cell number J:160533
Cdk5rap2Gt(RRO242)Byg/Cdk5rap2an
(involves: 129P2/OlaHsd * C57BL/6J)
decreased leukocyte cell number J:160533
Cdk5rap2tm1a(EUCOMM)Wtsi/Cdk5rap2tm1a(EUCOMM)Wtsi
(C57BL/6N-Cdk5rap2tm1a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:175295
Cdk6tm1.1Phin/Cdk6tm1.1Phin
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:144975
Cdk6tm1Bbd/Cdk6tm1Bbd
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal spleen morphology J:92529
abnormal spleen red pulp morphology J:92529
abnormal thymus morphology J:92529
decreased leukocyte cell number J:92529
decreased T cell proliferation J:92529
increased single-positive T cell number J:92529
small spleen J:92529
spleen hypoplasia J:92529
thymus cortex atrophy J:92529
thymus hypoplasia J:92529
Cdk6tm1Phin/Cdk6tm1Phin
(involves: 129S4/SvJae)
abnormal lymphopoiesis J:144975
abnormal T cell differentiation J:144975
abnormal thymocyte activation J:144975
decreased CD8-positive, alpha-beta T cell number J:144975
decreased double-negative T cell number J:144975
decreased double-positive T cell number J:144975
decreased thymocyte apoptosis J:144975
decreased thymocyte number J:144975
thymus atrophy J:144975
thymus hypoplasia J:144975
Cdk6tm1Phin/Cdk6tm1Phin
(involves: 129S4/SvJae * C57BL/6)
decreased DN1 thymic pro-T cell number J:174697
decreased DN2 thymocyte number J:174697
decreased double-positive T cell number J:174697
immune system phenotype J:174697
increased CD4-positive, alpha-beta T cell number J:174697
increased CD8-positive, alpha-beta T cell number J:174697
increased DN3 thymocyte number J:174697
Cdk6tm1Phin/Cdk6tm1Phin
Tg(Lck-Akt1*E40K)E-3Pnt/0

(involves: 129S4/SvJae)
abnormal T cell differentiation J:144975
Cdk6tm2.1Phin/Cdk6tm2.1Phin
(involves: 129 * C57BL/6 * FVB/N)
abnormal T cell differentiation J:174697
decreased DN1 thymic pro-T cell number J:174697
decreased DN2 thymocyte number J:174697
decreased DN4 thymocyte number J:174697
decreased double-positive T cell number J:174697
decreased thymocyte number J:174697
increased CD4-positive, alpha-beta T cell number J:174697
increased CD8-positive, alpha-beta T cell number J:174697
increased DN3 thymocyte number J:174697
increased double-negative T cell number J:174697
small thymus J:174697
Cdk6tm2.1Phin/Cdk6tm2.1Phin
Il2ratm1Dw/Il2ratm1Dw

(involves: 129S4/SvJae * C57BL/6 * FVB/N)
increased CD4-positive, alpha-beta T cell number J:174697
increased CD8-positive, alpha-beta T cell number J:174697
Cdk6tm3.1Phin/Cdk6tm3.1Phin
(involves: 129 * C57BL/6 * FVB/N)
abnormal T cell differentiation J:174697
enlarged thymus J:174697
immune system phenotype J:174697
increased CD4-positive, alpha-beta T cell number J:174697
increased DN1 thymic pro-T cell number J:174697
increased T cell apoptosis J:174697
increased thymocyte number J:174697
Cdk6tm4.1Phin/Cdk6tm4.1Phin
(involves: 129 * C57BL/6 * FVB/N)
abnormal T cell differentiation J:174697
decreased DN1 thymic pro-T cell number J:174697
decreased DN2 thymocyte number J:174697
decreased DN4 thymocyte number J:174697
decreased double-positive T cell number J:174697
decreased thymocyte number J:174697
immune system phenotype J:174697
increased CD4-positive, alpha-beta T cell number J:174697
increased CD8-positive, alpha-beta T cell number J:174697
increased DN3 thymocyte number J:174697
small thymus J:174697
Cdk10tm1.2Kald/Cdk10tm1.2Kald
(involves: 129 * C57BL/6 * FVB/N)
abnormal spleen morphology J:262333
Cdk12em1(IMPC)Tcp/Cdk12+
(C57BL/6NCrl-Cdk12em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Cdkl2tm1b(EUCOMM)Hmgu/Cdkl2tm1b(EUCOMM)Hmgu
(C57BL/6N-Cdkl2tm1b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
Cdkn1atm1.1(KOMP)Vlcg/Cdkn1atm1.1(KOMP)Vlcg
(C57BL/6N-Cdkn1atm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cdkn1atm1Led/Cdkn1atm1Led
(involves: 129S6/SvEvTac)
increased anti-double stranded DNA antibody level J:76041
increased anti-histone antibody level J:76041
increased anti-single stranded DNA antibody level J:76041
increased autoantibody level J:76041
increased T cell proliferation J:76041
Cdkn1atm1Led/Cdkn1atm1Led
Gadd45atm1Ajf/Gadd45atm1Ajf

(either: (involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6))
abnormal lymphopoiesis J:76041
abnormal T cell activation J:76041
decreased basophil cell number J:76041
decreased eosinophil cell number J:76041
decreased leukocyte cell number J:76041
decreased lymphocyte cell number J:76041
glomerulonephritis J:76041
increased anti-double stranded DNA antibody level J:76041
increased anti-histone antibody level J:76041
increased anti-single stranded DNA antibody level J:76041
increased autoantibody level J:76041
increased IgG1 level J:76041
increased IgM level J:76041
increased inflammatory response J:76041
increased T cell proliferation J:76041
Cdkn1atm1Led/Cdkn1atm1Led
Zbtb17tm1Cksn/Zbtb17tm1Cksn
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(B6.Cg-Zbtb17tm1Cksn Cdkn1atm1Led Commd10Tg(Vav1-icre)A2Kio)
arrested T cell differentiation J:170508
Cdkn1atm1Tyj/Cdkn1atm1Tyj
(B6;129S2-Cdkn1atm1Tyj/J)
decreased monocyte cell number J:108569
decreased susceptibility to induced arthritis J:108569
impaired macrophage chemotaxis J:108569
Cdkn1atm1Tyj/Cdkn1atm1Tyj
(involves: 129S2/SvPas * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:60292
abnormal self tolerance J:60292
abnormal thymus physiology J:70894
enlarged cervical lymph nodes J:60292
enlarged lymph nodes J:60292
enlarged spleen J:60292
glomerulonephritis J:60292, J:70894
immune system phenotype J:60292
increased anti-double stranded DNA antibody level J:60292
increased anti-histone antibody level J:60292
increased anti-nuclear antigen antibody level J:60292
increased B cell number J:60292
increased IgG1 level J:60292
increased memory T cell number J:60292
increased spleen weight J:60292
increased T cell proliferation J:60292
lymph node hyperplasia J:60292
spleen hyperplasia J:60292
Cdkn1atm1Tyj/Cdkn1atm1Tyj
Tg(MMTV-vHaras)SH1Led/0

(involves: 129S2/SvPas * C57BL/6J * CD-1 * FVB/N)
enlarged spleen J:66183
Cdkn1btm1Ako/Cdkn1btm1Ako
(involves: 129S1/Sv * C57BL/6)
increased spleen weight J:33401
increased thymocyte number J:33401
increased thymus weight J:33401
Cdkn1btm1Ako/Cdkn1btm1Ako
Cdkn2ctm1Yxi/Cdkn2ctm1Yxi

(involves: 129/Sv * 129S1/Sv * C57BL/6 * DBA/2)
enlarged spleen J:50053
enlarged thymus J:50053
Cdkn1btm1Jro/Cdkn1btm1Jro
(involves: 129S4/SvJaeSor * C57BL/6)
decreased T cell proliferation J:71780
Cdkn1btm1Kin/Cdkn1btm1Kin
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:33402
enlarged thymus J:33402
increased T cell number J:33402
thymus hyperplasia J:33402
Cdkn1btm1Kin/Cdkn1btm1Kin
Skp2tm1Kin/Skp2tm1Kin

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:74265
Cdkn1btm1Mlf/Cdkn1btm1Mlf
(involves: 129S4/SvJaeSor * C57BL/6J)
abnormal spleen morphology J:33400
abnormal thymus morphology J:33400
enlarged spleen J:33400
enlarged thymus J:33400
increased T cell proliferation J:33400
spleen hyperplasia J:33400
thymus hyperplasia J:33400
Cdkn1btm1Mlf/Cdkn1btm1Mlf
(involves: 129S4/SvJaeSor)
enlarged spleen J:107588
enlarged thymus J:107588
spleen hypoplasia J:107588
Cdkn1btm1Mlf/Cdkn1btm1Mlf
Myctm1Atp/Myc+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N)
decreased T cell proliferation J:73369
Cdkn1btm1Mlf/Cdkn1btm1Mlf
Tg(KRT5-CDK4)2303Mlrp/0

(involves: 129S4/SvJae * C57BL/6 * FVB * SENCAR * SSIN)
enlarged thymus J:107588
thymus hyperplasia J:107588
Cdkn1btm2Kin/Cdkn1btm2Kin
Rassf5tm1Kina/Rassf5tm1Kina

(involves: C57BL/6 * CBA)
immune system phenotype J:168749
Cdkn1btm3Jro/Cdkn1btm3Jro
(involves: 129S4/SvJaeSor)
enlarged spleen J:103819
enlarged thymus J:103819
Cdkn1ctm1Kat/Cdkn1ctm1Kat
(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen white pulp morphology J:61190
Cdkn2atm1Cjs/Cdkn2atm1Cjs
Nop53tm2.1Asuz/Nop53tm2.1Asuz
Tg(Lck-cre)#Jxm/0

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA)
decreased thymocyte number J:241062
Cdkn2atm1Rdp/Cdkn2atm1Rdp
(involves: 129/Sv * C57BL/6 * SJL)
abnormal spleen morphology J:53805
abnormal spleen red pulp morphology J:53805
increased spleen white pulp amount J:53805
Cdkn2atm1Rdp/Cdkn2atm1Rdp
Rnf2tm1Mvi/Rnf2tm1Mvi
Tg(Mx1-cre)1Cgn/0

(involves: 129 * C57BL/6 * C57BL/10 * CBA * SJL)
enlarged spleen J:130397
Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(Tyr-NRAS*Q61K)1Bee/?

(involves: 129/Sv * C57BL/6 * DBA/2 * SJL)
enlarged lymph nodes J:98545
Cdkn2atm2.1Rdp/Cdkn2atm2.1Rdp
(involves: 129S6/SvEvTac * FVB/N)
increased CD4-positive, alpha-beta T cell number J:71394
increased CD8-positive, alpha-beta T cell number J:71394
increased double-positive T cell number J:71394
increased splenocyte proliferation J:71394
increased thymus weight J:71394
thymus hyperplasia J:71394
Cdkn2btm1Bbd/Cdkn2btm1Bbd
(involves: 129S1/Sv * C57BL/6)
abnormal lymph node germinal center morphology J:63299
abnormal lymph node secondary follicle morphology J:63299
abnormal lymphocyte morphology J:63299
abnormal spleen marginal zone morphology J:63299
abnormal spleen morphology J:63299
increased mature B cell number J:63299
lymph node hyperplasia J:63299
lymphoid hyperplasia J:63299
spleen hyperplasia J:63299
Cdkn2btm1Bbd/Cdkn2btm1Bbd
Cdkn2ctm1Bbd/Cdkn2ctm1Bbd

(involves: 129S1/Sv * C57BL/6)
abnormal Langerhans cell morphology J:63299
abnormal lymphocyte morphology J:63299
enlarged spleen J:63299
lymph node hyperplasia J:63299
lymphoid hyperplasia J:63299
Cdkn2btm1Bbd/Cdkn2btm1Bbd
Pbx1tm1Koss/Pbx1tm1Koss
Nkx2-5tm2(cre)Rph/Nkx2-5+

(involves: 129P2/OlaHsd * 129S1/Sv)
abnormal spleen mesenchyme morphology J:184521
abnormal spleen morphology J:184521
Cdkn2btm1Wff/Cdkn2btm1Wff
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
increased monocyte cell number J:163498
myeloid hyperplasia J:163498
Cdkn2ctm1Bbd/Cdkn2ctm1Bbd
(involves: 129S1/Sv * C57BL/6)
abnormal lymph node medulla morphology J:63299
enlarged lymph nodes J:63299
enlarged spleen J:63299
increased spleen white pulp amount J:63299
lymphoid hyperplasia J:63299
Cdkn2ctm1Yxi/Cdkn2ctm1Yxi
(involves: 129/Sv * C57BL/6 * DBA/2)
abnormal T cell physiology J:50053
abnormal thymus size J:50053
enlarged spleen J:50053
increased B cell number J:50053
increased T cell number J:50053
spleen hyperplasia J:50053
thymus hyperplasia J:50053
Cds2Gt(OST184358)Lex/Cds2+
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased B cell number J:103485
increased T cell number J:103485
Cdsntm1.1Ics/Cdsntm1.1Ics
Tg(KRT14-cre/ERT2)1Ipc/0

(involves: 129S2/SvPas)
skin inflammation J:153292
Ceacam1Hv2-r/Ceacam1Hv2-r
(SJL/J)
decreased susceptibility to Coronaviridae infection J:92495
decreased susceptibility to viral infection J:25438
Ceacam1Hv2-s/Ceacam1Hv2-s
(Not Specified)
immune system phenotype J:92495
Ceacam1tm1.1Fta/Ceacam1tm1.1Fta
(C57BL/6(FVB)-Ceacam1tm1.1Fta)
decreased susceptibility to Coronaviridae infection J:198335
decreased susceptibility to Coronaviridae infection induced morbidity/mortality J:198335
Ceacam1tm1Bcn/Ceacam1tm1Bcn
(either: (involves: 129S1/Sv * 129X1/SvJ * BALB/c) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
decreased susceptibility to Coronaviridae infection induced morbidity/mortality J:70815
Ceacam1tm1Rsb/Ceacam1tm1Rsb
Tg(Lck-cre)1Cwi/0

(involves: 129)
abnormal cytokine secretion J:116136
increased interferon-gamma secretion J:116136
increased interleukin-2 secretion J:116136
increased T cell proliferation J:116136
Ceacam1tm2Bcn/Ceacam1tm2Bcn
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased susceptibility to Coronaviridae infection J:92376
Ceacam5em1(IMPC)Wtsi/Ceacam5em1(IMPC)Wtsi
(C57BL/6N-Ceacam5em1(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Ceat1CBA/J/Ceat1NOD
(involves: CBA/J * NOD-H2k)
increased susceptibility to experimental autoimmune thyroiditis J:77545
Ceat1NOD/Ceat1NOD
(involves: CBA/J * NOD-H2k)
increased susceptibility to experimental autoimmune thyroiditis J:77545
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1(Cebpb)Ylee
(involves: 129X1/SvJ * C57BL/6 * FVB/N)
immune system phenotype J:77646
Cebpatm1Dgt/Cebpatm1Dgt
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
abnormal myelopoiesis J:94682
decreased granulocyte number J:94682
failure of myelopoiesis J:94682
sepsis J:94682
Cebpatm1Gjd/Cebpatm1Gjd
(B6.129S7-Cebpatm1Gjd)
failure of myelopoiesis J:94682
Cebpatm1Nerl/Cebpatm1Nerl
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:72330
Cebpatm2Btp/Cebpatm2Btp
(B6.129P2-Cebpatm2Btp)
abnormal myelopoiesis J:187834
decreased neutrophil cell number J:187834
enlarged spleen J:187834
Cebpatm2Nerl/Cebpatm2Nerl
(involves: 129P2/OlaHsd * C57BL/6)
abnormal granulocyte morphology J:72330
decreased granulocyte number J:72330
immune system phenotype J:72330
Cebpatm3Nerl/Cebpatm3Nerl
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:72330
Cebpatm4Nerl/Cebpatm4Nerl
(involves: 129P2/OlaHsd * C57BL/6)
abnormal granulocyte morphology J:72330
decreased granulocyte number J:72330
immune system phenotype J:72330
Cebpatm8.1Nerl/Cebpatm8.1Nerl
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal granulocyte morphology J:136134
abnormal leukocyte morphology J:136134
abnormal myeloid leukocyte morphology J:136134
decreased granulocyte number J:136134
decreased monocyte cell number J:136134
decreased neutrophil cell number J:136134
enlarged spleen J:136134
liver inflammation J:136134
Cebpbtm1.1Acle/Cebpbtm1.1Acle
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal osteoclast differentiation J:150006
abnormal osteoclast morphology J:150006
abnormal osteoclast physiology J:150006
Cebpbtm1.1Elgaz/Cebpbtm1.1Elgaz
Lyz2em1.1(cre)Elgaz/Lyz2+

(BALB/cJ-Cebpbtm1.1Elgaz Lyz2em1.1Elgaz/Elgaz)
decreased circulating interleukin-10 level J:247885
decreased susceptibility to bacterial infection J:247885
decreased susceptibility to bacterial infection induced morbidity/mortality J:247885
increased circulating interleukin-6 level J:247885
increased circulating tumor necrosis factor level J:247885
Cebpbtm1Aki/Cebpbtm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:153025
abnormal T-helper 1 physiology J:153025
decreased susceptibility to endotoxin shock J:153025
granulomatous inflammation J:153025
increased susceptibility to bacterial infection J:153025
Cebpbtm1Kish/Cebpbtm1Kish
(involves: 129P2/OlaHsd)
abnormal macrophage physiology J:77003
impaired macrophage phagocytosis J:77003
increased interleukin-12 secretion J:126085
increased susceptibility to bacterial infection J:77003
Cebpbtm1Pfj/Cebpbtm1Pfj
(involves: 129S1/Sv * C57BL/6)
abnormal osteoclast differentiation J:150006
abnormal osteoclast morphology J:150006
abnormal osteoclast physiology J:150006
abnormal tumor necrosis factor level J:192313
Cebpbtm1Vpo/Cebpbtm1Vpo
(involves: 129S/SvEv * MF1)
abnormal cell-mediated immunity J:25215
abnormal humoral immune response J:25215
abnormal innate immunity J:25215
abnormal lymph node B cell domain morphology J:25215
abnormal lymph node cortex morphology J:25215
abnormal lymph node medulla morphology J:25215
abnormal lymph node medullary cord morphology J:25215
abnormal lymph node secondary follicle morphology J:25215
abnormal lymph node T cell domain morphology J:25215
abnormal macrophage physiology J:25215
abnormal mucosa-associated lymphoid tissue morphology J:25215
abnormal plasma cell morphology J:25215
abnormal spleen red pulp morphology J:25215
abnormal spleen secondary B follicle morphology J:25215
abnormal spleen white pulp morphology J:25215
abnormal T-helper 1 physiology J:25215
abnormal T-helper 2 physiology J:25215
decreased circulating interleukin-12 level J:25215
decreased susceptibility to type IV hypersensitivity reaction J:25215
enlarged axillary lymph nodes J:25215
enlarged inguinal lymph nodes J:25215
enlarged lymph nodes J:25215
enlarged mesenteric lymph nodes J:25215
enlarged spleen J:25215
enlarged submandibular lymph nodes J:25215
glomerulonephritis J:25215
increased circulating interleukin-6 level J:25215
increased IgG level J:25215
increased susceptibility to fungal infection J:25215
Cebpbtm2.1Acle/Cebpbtm2.1Acle
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal osteoclast morphology J:155795
decreased osteoclast cell number J:155795
increased circulating interleukin-6 level J:155795
Cebpbtm3Nerl/Cebpbtm3Nerl
(either: B6.129P2-Cebpbtm3Nerl or (involves: 129P2/OlaHsd * C57BL/6))
myositis J:153686
Cebpdtm1Pfj/Cebpdtm1Pfj
(involves: 129S1/Sv * C57BL/6)
abnormal cytokine level J:192313
decreased inflammatory response J:192313
Cebpetm1Kgx/Cebpetm1Kgx
(involves: 129S6/SvEvTac * NIH Black Swiss)
abnormal eosinophil differentiation J:76024
abnormal granulocyte differentiation J:76024
abnormal myelopoiesis J:76024
abnormal neutrophil differentiation J:76024
abnormal neutrophil morphology J:76024
abnormal neutrophil physiology J:76024
colitis J:76024
conjunctivitis J:76024
decreased eosinophil cell number J:76024
decreased granulocyte number J:76024
enlarged lymph nodes J:76024
impaired myelopoiesis J:76024
increased inflammatory response J:76024
increased plasma cell number J:76024
increased susceptibility to bacterial infection J:76024
lung inflammation J:76024
osteomyelitis J:76024
peritoneal inflammation J:76024
rhinitis J:76024
Cebpetm1Kgx/Cebpetm1Kgx
(involves: 129S6/SvEvTac)
abnormal eosinophil differentiation J:76024
abnormal granulocyte differentiation J:76024
abnormal myelopoiesis J:76024
abnormal neutrophil differentiation J:76024
abnormal neutrophil morphology J:76024
abnormal neutrophil physiology J:76024
colitis J:76024
conjunctivitis J:76024
decreased eosinophil cell number J:76024
decreased granulocyte number J:76024
enlarged lymph nodes J:76024
impaired myelopoiesis J:76024
increased inflammatory response J:76024
increased plasma cell number J:76024
increased susceptibility to bacterial infection J:76024
lung inflammation J:76024
osteomyelitis J:76024
peritoneal inflammation J:76024
pleuritis J:76024
rhinitis J:76024
Cebpgtm1Aki/Cebpgtm1Aki
(involves: 129P2/OlaHsd)
abnormal NK cell physiology J:58801
impaired natural killer cell mediated cytotoxicity J:58801
Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
(C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp)
enlarged lymph nodes J:211773
Celf4tm1a(EUCOMM)Wtsi/Celf4tm1a(EUCOMM)Wtsi
(C57BL/6N-Celf4tm1a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Celsr1ctb-2J/Celsr1ctb-2J
(STOCK Celsr1ctb-2J/GrsrJ)
increased susceptibility to otitis media J:229303
Celsr1ctb/Celsr1ctb
(CByJ.Cg-Celsr1ctb/GrsrJ)
increased susceptibility to otitis media J:229303
Celsr1em1(IMPC)Mbp/Celsr1+
(C57BL/6N-Celsr1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cemip2tm1.1Cya/Cemip2tm1.1Cya
Tg(CAG-cre/Esr1*)5Amc/0

(involves: C57BL/6 * CBA)
abnormal lymph node morphology J:317425
Cemiptm1.1Okda/Cemiptm1.1Okda
(involves: C57BL/6NCrlj * CBA/JNCrlj)
decreased osteoclast cell number J:241936
Cenpjtm1a(EUCOMM)Wtsi/Cenpjtm1a(EUCOMM)Wtsi
(B6Brd;B6N-Tyrc-Brd Cenpjtm1a(EUCOMM)Wtsi/Wtsi)
increased CD8-positive, alpha-beta T cell number J:194085
increased T cell number J:194085
Cep68em1(IMPC)J/Cep68em1(IMPC)J
(C57BL/6NJ-Cep68em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Cep76tm1b(EUCOMM)Hmgu/Cep76tm1b(EUCOMM)Hmgu
(C57BL/6N-Cep76tm1b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
Cep85lem1(IMPC)Mbp/Cep85lem1(IMPC)Mbp
(C57BL/6N-Cep85lem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Cep290b2b1454Clo/Cep290b2b1454Clo
(C57BL/6J-Cep290b2b1454Clo)
accessory spleen J:175213
spleen hypoplasia J:175213
Cep290b2b1752Clo/Cep290b2b1752Clo
(C57BL/6J-Cep290b2b1752Clo)
spleen hypoplasia J:175213
Cer1em1(IMPC)Ccpcz/Cer1em1(IMPC)Ccpcz
(C57BL/6NCrl-Cer1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Cerktm1Fbor/Cerktm1Fbor
(involves: BALB/c)
decreased granulocyte number J:131522
decreased neutrophil cell number J:131522
immune system phenotype J:131522
increased leukocyte cell number J:131522
increased susceptibility to bacterial infection J:131522
Cers1tm1b(EUCOMM)Hmgu/Cers1+
(C57BL/6N-Cers1tm1b(EUCOMM)Hmgu/H)
increased neutrophil cell number J:211773
Cers3tm1.1Rsnd/Cers3tm1.1Rsnd
(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to fungal infection J:179754
Cers6tm1.1Arte/Cers6tm1.1Arte
(involves: BALB/cJ * C57BL/6N)
decreased inflammatory response J:215519
Cers6tm1.1Kwi/Cers6tm1.1Kwi
(involves: 129P2/OlaHsd * C57BL/6)
microgliosis J:201327
Cfap53em1(IMPC)Wtsi/Cfap53em1(IMPC)Wtsi
(C57BL/6N-Cfap53em1(IMPC)Wtsi/Wtsi)
abnormal thymus topology J:239583
blood in lymph vessels J:239583
small spleen J:239583
Cfap161em1(IMPC)Ccpcz/Cfap161em1(IMPC)Ccpcz
(C57BL/6NCrl-Cfap161em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cfbtm1Hrc/Cfb+
Cfhtm1Mbo/Cfhtm1Mbo

(involves: 129S/Sv * C57BL/6)
decreased circulating complement protein level J:78193
Cfbtm1Hrc/Cfbtm1Hrc
(involves: 129S/Sv * C57BL/6)
abnormal complement pathway J:42679
impaired complement alternative pathway J:42679
Cfbtm1Hrc/Cfbtm1Hrc
(involves: 129S/Sv)
decreased susceptibility to Coronaviridae infection J:286325
impaired complement classical pathway J:130108
Cfbtm1Mbo/Cfbtm1Mbo
(involves: 129/Sv * C57BL/6)
increased susceptibility to bacterial infection J:83712
Cfbtm1Pkna/Cfbtm1Pkna
(D1.129P2-Cfbtm1Pkna)
decreased susceptibility to induced arthritis J:88872
Cfc1b2b2736.1Clo/Cfc1b2b2736.1Clo
(C57BL/6J-Cfc1b2b2736.1Clo)
accessory spleen J:175213
spleen hypoplasia J:175213
Cfc1tm1Cbm/Cfc1tm1Cbm
(Not Specified)
small spleen J:58530
spleen hypoplasia J:58530
Cfc1tm1Mms/Cfc1tm1Mms
(either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6J))
absent spleen J:58104
Cfdem1(IMPC)Mbp/Cfdem1(IMPC)Mbp
(C57BL/6NCrl-Cfdem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cfdtm1Yxu/Cfdtm1Yxu
(involves: 129P2/OlaHsd * C57BL/6J)
impaired complement alternative pathway J:73125
Cfdtm1Yxu/Cfdtm1Yxu
(B6.129P2-Cfdtm1Yxu)
impaired complement alternative pathway J:94855
increased susceptibility to bacterial infection J:94855
Cfhtm1.1Song/Cfhtm1.1Song
(involves: C57BL/6)
decreased circulating complement protein level J:240426
decreased complement C5 level J:240426
decreased serum complement activity J:240426
Cfhtm1Mbo/Cfh+
(involves: 129/Sv * C57BL/6)
decreased circulating complement protein level J:78193
Cfhtm1Mbo/Cfhtm1Mbo
(involves: 129/Sv * C57BL/6)
decreased circulating complement protein level J:78193
glomerulonephritis J:78193
increased susceptibility to type III hypersensitivity reaction J:78193
Cfhtm1Mbo/Cfhtm1Mbo
(involves: 129)
abnormal complement protein level J:125860
decreased circulating complement protein level J:125860, J:131403
glomerulonephritis J:131403
Cfhtm1Mbo/Cfhtm1Mbo
Tg(CAG-Cfh*)#Mcp/0

(involves: 129/Sv * C57BL/6 * CBA)
abnormal circulating complement protein level J:125860
abnormal complement protein level J:125860
Cfiem1Jiwe/Cfiem1Jiwe
(involves: C57BL/6J)
abnormal complement protein level J:308307
impaired complement alternative pathway J:308307
Cfitm1Mcp/Cfitm1Mcp
(involves: 129/Sv * C57BL/6)
decreased circulating complement protein level J:131403
Cflartm1.1Pope/Cflartm1.2Pope
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
abnormal abdominal lymph node morphology J:167430
abnormal B cell number J:167430
abnormal CD4-positive, alpha-beta T cell number J:167430
abnormal CD8-positive, alpha-beta T cell number J:167430
abnormal lymphocyte cell number J:167430
abnormal myelopoiesis J:167430
abnormal spleen B cell follicle morphology J:167430
abnormal spleen marginal zone morphology J:167430
abnormal spleen morphology J:167430
abnormal spleen red pulp morphology J:167430
abnormal thymus corticomedullary boundary morphology J:167430
abnormal thymus morphology J:167430
decreased macrophage cell number J:167430
enlarged spleen J:167430
increased CD8-positive, alpha-beta T cell number J:167430
increased eosinophil cell number J:167430
increased granulocyte number J:167430
increased leukocyte cell number J:167430
increased monocyte cell number J:167430
increased neutrophil cell number J:167430
Cflartm1Ywh/Cflartm1Ywh
Tg(Lck-cre)548Jxm/0

(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA)
decreased single-positive T cell number J:100558
increased thymocyte apoptosis J:100558
Cfmq1129X1/SvJ/Cfmq1C57BL/6J
Cftrtm1Unc/Cftrtm1Unc

(involves: 129X1/SvJ * C57BL/6J)
intestinal inflammation J:101842
Cfmq2129X1/SvJ/Cfmq2129X1/SvJ
Cftrtm1Unc/Cftrtm1Unc

(involves: 129X1/SvJ * C57BL/6J)
intestinal inflammation J:101842
Cfmq3129X1/SvJ/Cfmq3C57BL/6J
Cftrtm1Unc/Cftrtm1Unc

(involves: 129X1/SvJ * C57BL/6J)
intestinal inflammation J:101842
Cfptm1Cmst/Cfptm1Cmst
(B6.129P2-Cfptm1Cmst)
sepsis J:131526
Cfptm1Song/Y
(involves: 129 * C57BL/6)
abnormal complement pathway J:130108
impaired complement alternative pathway J:130108
impaired complement classical pathway J:130108
Cfptm1Song/Cfptm1Song
(involves: 129 * C57BL/6)
decreased susceptibility to induced arthritis J:165497
impaired complement alternative pathway J:165497
Cfptm2.1Song/Cfptm2.1Song
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * 129P2/OlaHsd * C57BL/6 * SJL)
decreased susceptibility to induced arthritis J:165497
impaired complement alternative pathway J:165497
Cfptm2.1Song/Cfptm2.1Song
Tg(EIIa-cre)C5379Lmgd/0

(involves: 129 * C57BL/6 * FVB/N * SJL)
impaired complement alternative pathway J:165497
Cftrtm1Bay/Cftrtm1Bay
(involves: 129S7/SvEvBrd * C57BL/6J)
acute pancreas inflammation J:15244
Cftrtm1Cam/Cftrtm1Cam
(involves: 129S/SvEv)
increased susceptibility to infection J:23850
peritoneal inflammation J:23850
Cftrtm1Hgu/Cftrtm1Hgu
(involves: 129P2/OlaHsd)
increased susceptibility to bacterial infection J:24119
lung inflammation J:24119
Cftrtm1Kth/Cftrtm1Kth
(involves: 129S7/SvEvBrd * C57BL/6J)
peritoneal inflammation J:29074
Cftrtm1Kth/Cftrtm1Kth
(B6.129S7-Cftrtm1Kth)
increased susceptibility to bacterial infection induced morbidity/mortality J:112450
lung inflammation J:112450
Cftrtm1Unc/Cftrtm1Unc
(B6.129P2-Cftrtm1Unc/J)
increased susceptibility to bacterial infection induced morbidity/mortality J:112450
lung inflammation J:58571, J:112450
Cftrtm1Unc/Cftrtm1Unc
(involves: 129P2/OlaHsd)
abnormal thymus involution J:2079
peritoneal inflammation J:2079
spleen hyperplasia J:2079
Cftrtm1Unc/Cftrtm1Unc
(B6.129P2-Cftrtm1Unc)
lung inflammation J:44904
Cftrtm1Unc/Cftrtm1Unc
Tg(FABPCFTR)1Jaw/0
Tg(Scgb1a1-Scnn1b)6608Bouc/0

(involves: 129P2/OlaHsd * C3H * C57BL/6 * FVB/N)
respiratory system inflammation J:191673
Cftrtm2Cam/Cftrtm2Cam
(involves: 129S/SvEv)
peritoneal inflammation J:27734
Cftrtm2Mrc/Cftrtm2Mrc
(B6.129S6-Cftrtm2Mrc)
abnormal alveolar macrophage morphology J:112450
decreased neutrophil cell number J:112450
increased susceptibility to bacterial infection induced morbidity/mortality J:112450
lung inflammation J:112450
Cftrtm3Hgu/Cftrtm3Hgu
(involves: 129P2/OlaHsd)
gallbladder inflammation J:32766
peritoneal inflammation J:32766
Cftrtm3Mrc/Cftrtm3Mrc
(B6.129S6-Cftrtm3Mrc)
increased susceptibility to bacterial infection induced morbidity/mortality J:112450
lung inflammation J:112450
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
(C57BL/6N-Cgastm1a(EUCOMM)Hmgu)
abnormal dendritic cell physiology J:201167
abnormal immune cell physiology J:201167
abnormal macrophage physiology J:201167
abnormal plasmacytoid dendritic cell physiology J:201167
decreased circulating interferon-alpha level J:201167
decreased circulating interferon-beta level J:201167
increased susceptibility to Herpesvirales infection J:201167
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:201167
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
(involves: C57BL/6N)
abnormal interferon secretion J:234263
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
Rnaseh2atm1Crh/Rnaseh2atm1Crh

(involves: C57BL/6N)
immune system phenotype J:232933
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
Trex1tm1Tld/Trex1tm1Tld

(involves: 129P2/OlaHsd * C57BL/6N)
increased susceptibility to Retroviridae infection J:234263
Cgastm1d(EUCOMM)Hmgu/Cgastm1d(EUCOMM)Hmgu
(involves: BALB/c * C57BL/6JJcl * C57BL/6N)
increased susceptibility to Flaviviridae infection J:207826
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:207826
increased susceptibility to Herpesvirales infection J:207826
increased susceptibility to Poxviridae infection J:207826
increased susceptibility to Poxviridae infection induced morbidity/mortality J:207826
Cgastm1d(EUCOMM)Hmgu/Cgastm1d(EUCOMM)Hmgu
(involves: C57BL/6N)
immune system phenotype J:265023
increased susceptibility to Retroviridae infection J:265023
Cgnz1NZM2328/J/Cgnz1NZM2328/J
(involves: C57L/J * NZM2328/J)
increased susceptibility to systemic lupus erythematosus J:71397
kidney inflammation J:71397
Cgref1em1(IMPC)J/Cgref1em1(IMPC)J
(C57BL/6NJ-Cgref1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Cgrrf1tm1b(KOMP)Wtsi/Cgrrf1tm1b(KOMP)Wtsi
(C57BL/6N-Cgrrf1tm1b(KOMP)Wtsi/Wtsi)
increased CD5-positive gamma-delta T cell number J:211773
increased gamma-delta T cell number J:211773
Ch25htm1Rus/Ch25htm1Rus
(B6.129S6-Ch25htm1Rus)
increased IgA level J:170807
increased IgG2a level J:170807
increased IgG2b level J:170807
increased IgG3 level J:170807
Chaf1btm2c(EUCOMM)Hmgu/Chaf1b+
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6J * C57BL/6N * CBA/J)
increased leukocyte cell number J:266848
Champ1em1(IMPC)Mbp/Champ1+
(C57BL/6NCrl-Champ1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Char2aC3H/HeJ/Char2aC3H/HeJ
(involves: C3H/HeJ * C57BL/6J)
increased susceptibility to parasitic infection J:117548
Char2bC3H/HeJ/Char2bC3H/HeJ
(involves: C3H/HeJ * C57BL/6J)
increased susceptibility to parasitic infection J:117548
Char3C3H/He/Char3C57BL/6
(involves: C3H/He * C57BL/6)
decreased susceptibility to parasitic infection J:72455
Char3C57BL/6/Char3C57BL/6
(involves: C3H/He * C57BL/6)
decreased susceptibility to parasitic infection J:72455
Char4C57BL/6J/Char4C57BL/6J
(involves: A/J * C57BL/6J)
decreased susceptibility to parasitic infection J:71471
Char9A/J/Char9C57BL/6J
(involves: A/J * C57BL/6J)
decreased susceptibility to parasitic infection J:122131
Char9C57BL/6J/Char9C57BL/6J
(involves: A/J * C57BL/6J)
decreased susceptibility to parasitic infection J:122131
Char11A/J/Char11C57BL/6J
(involves: A/J * C57BL/6J)
decreased susceptibility to parasitic infection J:106220
Char11C57BL/6J/Char11C57BL/6J
(involves: A/J * C57BL/6J)
decreased susceptibility to parasitic infection J:106220
Chchd7em3(IMPC)Tcp/Chchd7em3(IMPC)Tcp
(C57BL/6NCrl-Chchd7em3(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Chchd10em8Lutzy/Chchd10+
(C57BL/6NJ-Chchd10em8Lutzy/J)
increased susceptibility to otitis media J:272524
Chd2Gt(RRBO46)Byg/Chd2+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:146743
arteritis J:146176
decreased lymphocyte cell number J:146176
enlarged lymph nodes J:146743
enlarged spleen J:146743
heart inflammation J:146176
increased CD4-positive, alpha-beta T cell number J:146176
increased spleen red pulp amount J:146743
interstitial pneumonia J:146743
liver inflammation J:146743
lymphoid hyperplasia J:146176
myocarditis J:146743
Chd4tm1.1Kge/Chd4tm1.1Kge
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * SJL)
abnormal CD4-positive, alpha beta T cell morphology J:109547
abnormal T cell physiology J:109547
arrested T cell differentiation J:109547
decreased double-positive T cell number J:109547
increased CD8-positive, alpha-beta T cell number J:109547
lymph node hypoplasia J:109547
spleen hypoplasia J:109547
Chd4tm1.1Kge/Chd4tm1.2Kge
Tg(CAG-Bgeo/GFP)21Lbe/0
Tg(Lck-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
decreased T cell proliferation J:109547
Chd4tm1.1Kge/Chd4tm1.2Kge
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * SJL)
thymus hypoplasia J:109547
Chd4tm1.2Kge/Chd4tm1.2Kge
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal T cell differentiation J:109547
decreased double-positive T cell number J:109547
decreased T cell proliferation J:109547
increased CD8-positive, alpha-beta T cell number J:109547
increased double-negative T cell number J:109547
thymus hypoplasia J:109547
Chd5em1(IMPC)Mbp/Chd5em1(IMPC)Mbp
(C57BL/6NCrl-Chd5em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Chd6em1(IMPC)Mbp/Chd6em1(IMPC)Mbp
(C57BL/6N-Chd6em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Chd7Flo/Chd7+
(involves: C3HeB/FeJ)
keratoconjunctivitis sicca J:104123
Chd7Gt(RRR136)Byg/Chd7+
(involves: 129P2/OlaHsd * C57BL/6)
ectopic thymus J:154590
small thymus J:154590
thymus hypoplasia J:154590
Chd7Gt(XK403)Byg/Chd7+
Tbx1tm1Bld/Tbx1+

(either: (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1))
ectopic thymus J:154590
Chd7Looper/Chd7+
(BALB/c-Chd7Looper)
blepharitis J:252089
conjunctivitis J:252089
Chd7Ome/Chd7+
(involves: BALB/cByJ * C57BL/6J)
increased susceptibility to otitis media J:187200
Chd7tm2a(EUCOMM)Wtsi/Chd7+
(involves: 129S5/SvEvBrd * C57BL/6N)
decreased leukocyte cell number J:330596
decreased monocyte cell number J:330596
increased NK T cell number J:330596
Chd7Trooper/Chd7+
(BALB/c-Chd7Trooper)
blepharitis J:262283
conjunctivitis J:262283
Chd7Whi/Chd7+
(C3HeB/FeJ-Chd7Whi)
decreased monocyte cell number J:330596
increased NK T cell number J:330596
Chd7Whi/Chd7+
(involves: C3HeB/FeJ)
keratoconjunctivitis sicca J:104123
Chd9tm1a(EUCOMM)Wtsi/Chd9tm1a(EUCOMM)Wtsi
(C57BL/6N-Chd9tm1a(EUCOMM)Wtsi/Wtsi)
increased Langerhans cell number J:211773
Chek2tm1Mak/Chek2+
Rad50tm2Jpt/Rad50tm2Jpt

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
abnormal pro-B cell morphology J:103922
decreased double-negative T cell number J:103922
decreased macrophage cell number J:103922
Chi3l1tm1Eli/Chi3l1tm1Eli
(B6.Cg-Chi3l1tm1Eli)
abnormal dendritic cell physiology J:148490
abnormal macrophage morphology J:148490
abnormal plasmacytoid dendritic cell physiology J:148490
abnormal T-helper 2 physiology J:148490
decreased IgE level J:148490
decreased interleukin-4 secretion J:148490
decreased interleukin-13 secretion J:148490
decreased splenocyte proliferation J:148490
decreased T-helper 2 cell number J:148490
impaired eosinophil recruitment J:148490
impaired neutrophil recruitment J:148490
increased T cell apoptosis J:148490
Chi3l1tm1Eli/Chi3l1tm1Eli
Tg(Scgb1a1-rtTA,-tTS,tetO-CHI3L1)1Eli/0

(involves: 129 * C57BL/6)
immune system phenotype J:148490
Chi3l1tm1Eli/Chi3l1tm1Eli
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli/0

(involves: C57BL/6 * CBA)
abnormal T-helper 2 cell number J:148490
abnormal T-helper 2 physiology J:148490
Chia1tm1.1Lof/Chia1tm1.1Lof
(C57BL/6-Chia1tm1.1Lof)
decreased interleukin-13 secretion J:257728
immune system phenotype J:257728
increased lymphocyte cell number J:257728
increased neutrophil cell number J:257728
Chic2tm1b(EUCOMM)Wtsi/Chic2+
(C57BL/6N-Chic2tm1b(EUCOMM)Wtsi/H)
enlarged spleen J:211773
Chit1tm1Eli/Chit1tm1Eli
(involves: C57BL/6)
decreased susceptibility to bacterial infection J:189872
Chit1tm1Eli/Chit1tm1Eli
Tg(Scgb1a1-Il13)2Eli/0

(involves: C57BL/6 * CBA)
decreased susceptibility to bacterial infection J:189872
Chit1tm1Eli/Chit1tm1Eli
Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli/0

(involves: C57BL/6)
decreased susceptibility to bacterial infection J:189872
Chmp2bem1(IMPC)Mbp/Chmp2b+
(C57BL/6NCrl-Chmp2bem1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Chmp4ctm1b(EUCOMM)Wtsi/Chmp4ctm1b(EUCOMM)Wtsi
(C57BL/6N-Chmp4ctm1b(EUCOMM)Wtsi/H)
decreased basophil cell number J:211773
Chordc1em1(IMPC)Mbp/Chordc1+
(C57BL/6N-Chordc1em1(IMPC)Mbp/MbpMmucd)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Chordc1tm1Mbra/Chordc1+
(involves: 129 * C57BL/6)
abnormal myelopoiesis J:222040
abnormal spleen morphology J:222040
enlarged spleen J:222040
increased leukocyte cell number J:222040
Chrdtm1Emdr/Chrdtm1Emdr
(either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J))
athymia J:83662
Chrdtm1Emdr/Chrdtm1Emdr
(129S6.129-Chrdtm1Emdr)
athymia J:146769
Chrdtm1Emdr/Chrdtm1Emdr
Tbx1m1Jlk/Tbx1m1Jlk

(129/Sv-Tbx1m1Jlk Chrdtm1Emdr)
athymia J:146769
Chrm1tm1Jwe/Chrm1tm1Jwe
(involves: 129S6/SvEvTac * CF-1)
decreased cytotoxic T cell cytolysis J:106393
Chrna3tm1Bay/Chrna3tm1Bay
(involves: 129S7/SvEvBrd * C57BL/6)
increased susceptibility to bacterial infection J:54994
urinary bladder inflammation J:54994
Chrna4tm1Jpc/Chrna4tm1Jpc
(involves: C57BL/6)
decreased IgG level J:103908
decreased immunoglobulin level J:103908
immune system phenotype J:103908
increased IgG level J:103908
Chrna5em1(IMPC)H/Chrna5em1(IMPC)H
(C57BL/6N-Chrna5em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Chrna7tm1Bay/Chrna7tm1Bay
(involves: 129S7/SvEvBrd * C57BL/6J)
decreased neutrophil cell number J:140280
increased lymphocyte cell number J:140280
Chrna7tm1Bay/Chrna7tm1Bay
(B6.Cg-Chrna7tm1Bay)
abnormal interleukin level J:89610
abnormal tumor necrosis factor level J:89610
Chrna7tm1Bay/Chrna7tm1Bay
(involves: 129S7/SvEvBrd * C57BL/6)
decreased IgG level J:103908
decreased immunoglobulin level J:103908
immune system phenotype J:103908
Chrna10em1(IMPC)Mbp/Chrna10em1(IMPC)Mbp
(C57BL/6NCrl-Chrna10em1(IMPC)Mbp/MbpMmucd)
increased basophil cell number J:211773
increased monocyte cell number J:211773
Chrnb2tm1Jpc/Chrnb2tm1Jpc
(B6.129P2-Chrnb2tm1Jpc)
decreased B cell number J:112766
Chrnb2tm1Jpc/Chrnb2tm1Jpc
(involves: 129P2/OlaHsd * C57BL/6J)
myeloid hyperplasia J:140280
Chrnb2tm1Jpc/Chrnb2tm1Jpc
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune system physiology J:103908
abnormal immunoglobulin level J:103908
decreased B cell number J:103908
decreased immunoglobulin level J:103908
immune system phenotype J:103908
increased B cell proliferation J:103908
increased IgG level J:103908
Chrnb2tm1Mdb/Chrnb2tm1Mdb
Chrnb4tm1Mdb/Chrnb4tm1Mdb

(involves: 129S7/SvEvBrd * C57BL/6J)
increased susceptibility to bacterial infection J:73590
urinary bladder inflammation J:73590
Chst1tm1(KOMP)Vlcg/Chst1tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
decreased B cell number J:204813
immune system phenotype J:204813
increased T cell number J:204813
Chst1tm1(KOMP)Vlcg/Chst1tm1(KOMP)Vlcg
Chst2tm1Tmu/Chst2tm1Tmu
Chst4tm1Sdr/Chst4tm1Sdr

(involves: 129S2/SvPas * C57BL/6NTac)
abnormal leukocyte migration J:204813
Chst2em1(IMPC)Mbp/Chst2em1(IMPC)Mbp
(C57BL/6N-Chst2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Chst2tm1Tmu/Chst2tm1Tmu
(involves: 129S2/SvPas * C57BL/6J)
abnormal leukocyte migration J:92231
abnormal leukocyte physiology J:92231
Chst2tm1Tmu/Chst2tm1Tmu
Chst4tm1Sdr/Chst4tm1Sdr

(involves: 129S2/SvPas)
abnormal leukocyte migration J:204813
Chst3tm1Tmu/Chst3tm1Tmu
(involves: 129S2/SvPas * 129X1/SvJ)
decreased T cell number J:73698
Chst3tm1Tmu/Chst3tm1Tmu
(involves: 129S2/SvPas)
decreased neutrophil cell number J:217719
increased T cell proliferation J:217719
lymph node hypoplasia J:217719
Chst4tm1Mifu/Chst4tm1Mifu
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal leukocyte migration J:113195
impaired leukocyte tethering or rolling J:113195
Chst4tm1Mifu/Chst4tm1Mifu
Gcnt1tm1Jxm/Gcnt1tm1Jxm

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal leukocyte migration J:113195
impaired leukocyte tethering or rolling J:113195
Chst4tm1Sdr/Chst4tm1Sdr
(involves: C57BL/6)
abnormal leukocyte adhesion J:86759
abnormal leukocyte migration J:86759
abnormal lymph node morphology J:86759
abnormal lymph node primary follicle morphology J:86759
Chst10em1(IMPC)Hmgu/Chst10em1(IMPC)Hmgu
(C57BL/6NCrl-Chst10em1(IMPC)Hmgu/Ieg)
increased spleen weight J:211773
Chst11tm1a(KOMP)Wtsi/Chst11tm1a(KOMP)Wtsi
(C57BL/6N-Chst11tm1a(KOMP)Wtsi/Wtsi)
abnormal thymus morphology J:239583
blood in lymph vessels J:239583
Chst15tm1Oh/Chst15tm1Oh
(involves: 129P2/OlaHsd * C57BL/6)
abnormal mast cell morphology J:165927
Chsy1em1(IMPC)Mbp/Chsy1em1(IMPC)Mbp
(C57BL/6NCrl-Chsy1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Chsy1skt/Chsy1skt
Pde6b+/Pde6b+

(mixed)
decreased macrophage cell number J:286529
decreased neutrophil cell number J:286529
kidney inflammation J:286529
microgliosis J:286529
Chsy1skt/Chsy1tm1Lex
(mixed)
microgliosis J:286529
Chsy1tm1Lex/Chsy1tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
arthritis J:171883
microgliosis J:286529
Chtoptm1a(EUCOMM)Wtsi/Chtoptm1a(EUCOMM)Wtsi
(C57BL/6N-Chtoptm1a(EUCOMM)Wtsi/Wtsi)
absent spleen J:239583
spleen hypoplasia J:239583
Chukem1(IMPC)Ccpcz/Chuk+
(C57BL/6NCrl-Chukem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Chuktm1Lex/Chuktm1Lex
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S/SvEvBrd)
impaired macrophage chemotaxis J:159873
impaired neutrophil chemotaxis J:159873
impaired neutrophil recruitment J:159873
Chuktm1Mka/Chuktm1Mka
(B6.129-Chuktm1Mka)
abnormal B cell physiology J:113556
Chuktm1Mpa/Chuktm1Mpa
Ikbkbtm2Cgn/Ikbkbtm2Cgn
Tg(Alb1-cre)7Gsc/0

(involves: C57BL/6 * FVB/N)
increased susceptibility to endotoxin shock J:137861
Chuktm2Mka/Chuktm2Mka
(B6.Cg-Chuktm2Mka)
abnormal B cell physiology J:113556
Chuktm2Mka/Chuktm2Mka
Tg(Tnfsf13b)1Fma/?

(B6.Cg-Chuktm2Mka Tg(Tnfsf13b)1Fma)
abnormal B cell activation J:113556
absent spleen marginal zone J:113556
decreased marginal zone B cell number J:113556
increased anti-double stranded DNA antibody level J:113556
increased transitional stage B cell number J:113556
Chuktm2Yhu/Chuktm2Yhu
(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
skin inflammation J:197037
Chuktm2Yhu/Chuktm2Yhu
Tg(Lor-CHUK)8Yhu/0

(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
absent lymph nodes J:197037
Chuktm2Yhu/Chuktm2Yhu
Tg(Lor-CHUK)8Yhu/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
increased CD4-positive, alpha-beta T cell number J:197037
increased CD8-positive, alpha-beta T cell number J:197037
increased macrophage cell number J:197037
increased neutrophil cell number J:197037
lung inflammation J:197037
Churc1tm1b(EUCOMM)Wtsi/Churc1tm1b(EUCOMM)Wtsi
(C57BL/6N-Churc1tm1b(EUCOMM)Wtsi/Wtsi)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased effector memory T-helper cell number J:211773
Cia2DBA/1J/Cia2DBA/1J
(involves: DBA/1J * SWR/J)
abnormal immune system physiology J:53356
Cia2DBA/1J/Cia2DBA/1J
(involves: DBA/1J * FVB/N)
increased susceptibility to induced arthritis J:116665
Cia2DBA/1J/Cia2SWR/J
(involves: DBA/1J * SWR/J)
abnormal immune system physiology J:53356
Cia5C57BL/10/Cia5C57BL/10
(involves: B10.RIII * RIIIS/J)
abnormal inflammatory response J:50472
Cia5bRIIIS/J/?
(involves: C57BL/10 * RIIIS/J)
decreased susceptibility to induced arthritis J:101767
Cia5bRIIIS/J/Cia5bRIIIS/J
Cia32B10.RIII/Cia32RIIIS/J

(involves: C57BL/10 * RIIIS/J)
decreased susceptibility to induced arthritis J:101767
Cia5cRIIIS/J/?
(involves: C57BL/10 * RIIIS/J)
decreased susceptibility to induced arthritis J:101767
Cia6C57BL/10SnSg/Cia6C57BL/10SnSg
(involves: B10.Q * DBA/1)
abnormal inflammatory response J:57012
Cia6C57BL/10SnSg/Cia6DBA/1J
(involves: B10.Q * DBA/1)
abnormal inflammatory response J:57012
Cia6DBA/1J/Cia6DBA/1J
(involves: B10.Q * DBA/1)
decreased inflammatory response J:57012
Cia7DBA/1J/Cia7C57BL/10SnSg
(involves: B10.Q * DBA/1)
increased inflammatory response J:57012
Cia7DBA/1J/Cia7DBA/1J
(involves: B10.Q * DBA/1)
increased inflammatory response J:57012
increased susceptibility to induced arthritis J:122130
Cia8DBA/1J/Cia8DBA/1J
(involves: B10.Q * DBA/1)
increased inflammatory response J:57012
Cia9C57BL/10SnSg/Cia9NOD/ShiLtJ
(involves: B10.D1-H2q/SgJ * NOD.C3-H2q/Rhd)
increased inflammatory response J:69981
Cia9NOD/ShiLtJ/Cia9NOD/ShiLtJ
(involves: B10.D1-H2q/SgJ * NOD.C3-H2q/Rhd)
abnormal immune system physiology J:69981
Cia10C57BL/10/Cia10C57BL/10
(involves: C57BL/10 * RIIIS/J)
abnormal inflammatory response J:50472
Cia10C57BL/10/Cia10C57BL/10
Cia5C57BL/10/Cia5C57BL/10

(involves: C57BL/10 * RIIIS/J)
abnormal inflammatory response J:50472
Cia23C57BL/10SnSg/Cia23C57BL/10SnSg
(involves: B10.D1-H2q/SgJ * NOD.C3-H2q/Rhd)
abnormal inflammatory response J:69981
Cia23C57BL/10SnSg/Cia23NOD/ShiLtJ
(involves: B10.D1-H2q/SgJ * NOD.C3-H2q/Rhd)
abnormal inflammatory response J:69981
Cia23C57BL/10SnSg/Cia23NOD/ShiLtJ
Cia9C57BL/10SnSg/Cia9C57BL/10SnSg

(involves: B10.D1-H2q/SgJ * NOD.C3-H2q/Rhd)
decreased inflammatory response J:69981
Cia26RIIIS/J/Cia26RIIIS/J
Cia30B10.RIII/?

(involves: B10.RIII * RIIIS/J)
arthritis J:95848
Cia27DBA/1J/?
(involves: DBA/1J * FVB/N)
increased IgG level J:116665, J:94347
Cia30RIIIS/J/Cia30RIIIS/J
Cia5B10.RIII/Cia5B10.RIII

(involves: B10.RIII * RIIIS/J)
decreased susceptibility to induced arthritis J:95848
Cia31B10.RIII/Cia31RIIIS/J
Cia5B10.RIII/Cia5B10.RIII

(involves: B10.RIII * RIIIS/J)
arthritis J:95848
Cia31B10.RIII/Cia31RIIIS/J
Cia5RIIIS/J/Cia5RIIIS/J

(involves: C57BL/10 * RIIIS/J)
decreased susceptibility to induced arthritis J:101767
Cia32B10.RIII/Cia32RIIIS/J
Cia5B10.RIII/Cia5B10.RIII

(involves: B10.RIII * RIIIS/J)
arthritis J:95848
Cia34DBA/1J/Cia34DBA/1J
(involves: C57BL/10 * DBA/1J)
decreased autoantibody level J:122130
decreased susceptibility to induced arthritis J:122130
Cia35C57BL/10SnSg/Cia35C57BL/10SnSg
Cia42DBA/1J/Cia42DBA/1J

(involves: B10.Q * DBA/1)
decreased susceptibility to induced arthritis J:122130
Cia35C57BL/10SnSg/Cia35DBA/1J
(involves: C57BL/10 * DBA/1J)
increased autoantibody level J:122130
increased susceptibility to induced arthritis J:122130
Cia35C57BL/10SnSg/Cia35DBA/1J
Cia42DBA/1J/Cia42DBA/1J

(involves: B10.Q * DBA/1)
decreased susceptibility to induced arthritis J:122130
Cia35DBA/1J/Cia35DBA/1J
Cia42DBA/1J/Cia42DBA/1J

(involves: B10.Q * DBA/1)
decreased susceptibility to induced arthritis J:122130
Cia36DBA/1J/Cia36DBA/1J
(involves: C57BL/10 * DBA/1J)
decreased autoantibody level J:122130
decreased susceptibility to induced arthritis J:122130
Cia37C57BL/10SnSg/Cia37DBA/1J
(involves: C57BL/10 * DBA/1J)
increased autoantibody level J:122130
increased susceptibility to induced arthritis J:122130
Cia38DBA/1J/Cia38DBA/1J
(involves: C57BL/10 * DBA/1J)
increased autoantibody level J:122130
increased susceptibility to induced arthritis J:122130
Cia39C57BL/10Sn/Cia39C57BL/10Sn
(involves: B10.Q/Lund-H2q * B10.RIII/Lund-H2r)
decreased susceptibility to induced arthritis J:97801
Cia39RIII/WySn/Cia39RIII/WySn
(involves: B10.Q/Lund-H2q * B10.RIII/Lund-H2r)
arthritis J:97801
Cia40C57BL/10SnSg/Cia40C57BL/10SnSg
(involves: C57BL/10SnSg * DBA/1J * NFS/N)
increased susceptibility to induced arthritis J:106522
Cia43DBA/1J/Cia43FVB/N
(involves: DBA/1J * FVB/N)
increased susceptibility to induced arthritis J:146242
Cia43FVB/N/Cia43FVB/N
(involves: DBA/1J * FVB/N)
increased susceptibility to induced arthritis J:146242
Ciaaq1DBA/1J/Ciaaq1DBA/1J
(involves: DBA/1J * FVB/NJ)
increased autoantibody level J:122919
Ciaaq1DBA/1J/Ciaaq1FVB/NJ
(involves: DBA/1J * FVB/NJ)
increased autoantibody level J:122919
Ciao2bem1(IMPC)Ccpcz/Ciao2b+
(C57BL/6N-Ciao2bem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Cib1tm1b(EUCOMM)Hmgu/Cib1tm1b(EUCOMM)Hmgu
(C57BL/6N-Cib1tm1b(EUCOMM)Hmgu/Bay)
decreased eosinophil cell number J:211773
decreased neutrophil cell number J:211773
increased large unstained cell number J:211773
increased monocyte cell number J:211773
Cib2tm1b(EUCOMM)Wtsi/Cib2tm1b(EUCOMM)Wtsi
(C57BL/6N-Cib2tm1b(EUCOMM)Wtsi/H)
increased basophil cell number J:211773
Cibar1tm1b(KOMP)Wtsi/Cibar1tm1b(KOMP)Wtsi
(C57BL/6N-Cibar1tm1b(KOMP)Wtsi/Wtsi)
decreased leukocyte cell number J:274784, J:211773
Cidebtm1Pli/Cidebtm1Pli
(Not Specified)
decreased spleen weight J:126556
Cigs2tm1.1Anse/Cigs2+
Il4tm1(CD2)Mmrs/Il4+

(involves: 129 * BALB/cJ * C57BL/6)
decreased basophil cell number J:181313
decreased IgE level J:181313
decreased IgG1 level J:181313
decreased interleukin-4 secretion J:181313
immune system phenotype J:181313
Cigs2tm1.1Anse/Cigs2tm1.1Anse
(involves: BALB/cJ * C57BL/6)
abnormal class switch recombination J:181313
abnormal humoral immune response J:181313
abnormal susceptibility to infection J:181313
decreased IgE level J:181313
decreased IgG1 level J:181313
decreased interleukin-4 secretion J:181313
decreased interleukin-13 secretion J:181313
increased IgG2b level J:181313
Cigs2tm1.1Kubo/Cigs2tm1.1Kubo
(B6.Cg-Cigs2tm1.1Kubo)
abnormal interleukin secretion J:129048
abnormal mast cell physiology J:129048
abnormal neutrophil physiology J:129048
decreased interleukin-4 secretion J:167446, J:129048
decreased interleukin-13 secretion J:129048
Ciitam1Btlr/Ciitam1Btlr
(C57BL/6J-Ciitam1Btlr)
abnormal CD4-positive T cell differentiation J:221483
abnormal CD8-positive, alpha-beta T cell differentiation J:221483
impaired humoral immune response J:221483
Ciitatm1.1Dim/Ciitatm1.1Dim
(involves: 129S2/SvPas * C57BL/6 * SJL)
abnormal level of surface class II molecules J:51885
decreased CD4-positive, alpha-beta T cell number J:51885
decreased dendritic cell number J:51885
Ciitatm1Adm/Ciita+
(involves: 129S1/Sv * C57BL/6)
abnormal immune system physiology J:117111
Ciitatm1Adm/Ciitatm1Adm
(involves: 129S1/Sv * C57BL/6)
abnormal immune system physiology J:117111
Ciitatm1Ccum/Ciitatm1Ccum
(involves: 129S2/SvPas * C57BL/6J)
abnormal B cell physiology J:96421
abnormal CD4-positive, alpha-beta T cell physiology J:31601
abnormal cytokine secretion J:64283
abnormal dendritic cell physiology J:96421
abnormal level of surface class II molecules J:31601, J:96421
abnormal lymphocyte physiology J:96421
abnormal MHC II cell surface expression on macrophages J:31601
abnormal popliteal lymph node morphology J:64283
abnormal susceptibility to infection J:64283
abnormal T cell differentiation J:64283
abnormal T cell physiology J:31601
decreased CD4-positive, alpha-beta T cell number J:31601
decreased susceptibility to parasitic infection J:64283
decreased T cell proliferation J:31601
increased CD4-positive, alpha-beta T cell number J:64283
increased CD8-positive, alpha-beta T cell number J:64283
increased susceptibility to parasitic infection J:64283
Ciitatm1Ccum/Ciitatm1Ccum
(NOD.129S2(B6)-Ciitatm1Ccum)
abnormal inflammatory response J:106081
abnormal level of surface class II molecules J:106081
abnormal T cell differentiation J:106081
decreased CD4-positive, alpha-beta T cell number J:106081
decreased susceptibility to autoimmune diabetes J:107051
increased CD8-positive, alpha-beta T cell number J:106081
insulitis J:107051
pancreas inflammation J:106081
periinsulitis J:106081
Ciitatm1Ccum/Ciitatm1Ccum
(involves: 129S2/SvPas * C57BL/6)
abnormal level of surface class II molecules J:67941
Ciitatm1Jpyt/Ciitatm1Jpyt
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal T cell subpopulation ratio J:57100
decreased CD4-positive, alpha-beta T cell number J:57100
decreased IgG level J:57100
increased CD8-positive, alpha-beta T cell number J:57100
increased double-positive T cell number J:57100
increased IgM level J:57100
Ciitatm1Jpyt/Ciitatm1Jpyt
(B6.129P2-Ciitatm1Jpyt)
abnormal T-helper 1 physiology J:125654
decreased susceptibility to experimental autoimmune encephalomyelitis J:125654
Ciitatm1Wrth/Ciitatm1Wrth
(B6.129P2-Ciitatm1Wrth)
immune system phenotype J:117111
Ciitatm1Wrth/Ciitatm1Wrth
(involves: 129P2/OlaHsd * C57BL/6)
absent CD4-positive, alpha-beta T cells J:233241
increased osteoclast cell number J:233241
Ciitatm2Wrth/Ciitatm2Wrth
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immunoglobulin level J:92170
decreased CD4-positive, alpha-beta T cell number J:92170
Ciitatm2Wrth/Ciitatm2Wrth
(B6.129P2-Ciitatm2Wrth)
immune system phenotype J:117111
Cilk1tm1b(KOMP)Mbp/Cilk1tm1b(KOMP)Mbp
(C57BL/6N-Cilk1tm1b(KOMP)Mbp/Ucd)
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Cimap1bem1(IMPC)Ccpcz/Cimap1bem1(IMPC)Ccpcz
(C57BL/6NCrl-Cimap1bem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased NK T cell number J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Cimap2Retro/Cimap2+
(involves: C57BL/6J)
increased CD8-positive, alpha-beta T cell number J:223336
increased cytotoxic T cell cytolysis J:223336
Cimap2Retro/Cimap2Retro
(involves: C57BL/6J)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:223336
increased activated T cell number J:223336
increased CD8-positive, alpha-beta T cell number J:223336
increased central memory CD8 positive, alpha-beta T cell number J:223336
increased cytotoxic T cell cytolysis J:223336
increased interferon-gamma secretion J:223336
increased susceptibility to Riboviria infection induced morbidity/mortality J:223336
increased T cell proliferation J:223336
Cimap2tm1a(KOMP)Wtsi/Cimap2+
(involves: C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:223336
decreased cytotoxic T cell cytolysis J:223336
Cimip2btm1(KOMP)Wtsi/Cimip2btm1(KOMP)Wtsi
(C57BL/6N-Cimip2btm1(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Cinda1BALB/c/?
(involves: BALB/c * CcS-4/Dem)
increased T cell proliferation J:40728
Cinda2STS/A/?
(involves: BALB/c * CcS-4/Dem)
increased T cell proliferation J:40728
Cinda3O20/A/Cinda3O20/A
(involves: O20/A * OcB-9/Dem)
decreased T cell proliferation J:95917
Cinda3OcB9/Dem/Cinda3O20/A
(involves: O20/A * OcB-9/Dem)
increased T cell proliferation J:95917
Cinda4OcB9/Dem/Cinda4O20/A
(involves: O20/A * OcB-9/Dem)
increased T cell proliferation J:95917
Cinda4OcB9/Dem/Cinda4OcB9/Dem
(involves: O20/A * OcB-9/Dem)
increased T cell proliferation J:95917
Cinda5OcB9/Dem/Cinda5O20/A
(involves: O20/A * OcB-9/Dem)
increased T cell proliferation J:95917
Cinda5OcB9/Dem/Cinda5OcB9/Dem
(involves: O20/A * OcB-9/Dem)
increased T cell proliferation J:95917
Cishtm1.1Cdon/Cishtm1.1Cdon
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:204829
Cishtm1.1Cdon/Cishtm1.1Cdon
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal T-helper 2 cell differentiation J:204829
increased eosinophil cell number J:204829
increased interleukin-4 secretion J:204829
increased interleukin-5 secretion J:204829
increased interleukin-10 secretion J:204829
increased interleukin-13 secretion J:204829
increased susceptibility to type I hypersensitivity reaction J:204829
Cishtm1.2Cdon/Cishtm1.2Cdon
(B6.129S6(Cg)-Cishtm1.2Cdon)
abnormal CD4-positive T cell differentiation J:204829
abnormal immune system morphology J:204829
abnormal immune system physiology J:204829
abnormal T-helper 2 cell differentiation J:204829
immune system phenotype J:204829
increased eosinophil cell number J:204829
increased interleukin-4 secretion J:204829
increased interleukin-5 secretion J:204829
increased interleukin-9 secretion J:204829
increased interleukin-13 secretion J:204829
increased lymphocyte cell number J:204829
increased susceptibility to type I hypersensitivity reaction J:204829
increased T cell proliferation J:204829
lung inflammation J:204829
lymph node hyperplasia J:204829
spleen hyperplasia J:204829
thymus hyperplasia J:204829
Cited2tm1Bha/Cited2tm1Bha
(involves: 129P2/OlaHsd * C57BL/6J)
small spleen J:92872
Cited2tm1Bha/Cited2tm1Bha
(B6.129P2-Cited2tm1Bha)
small spleen J:92872
Ciz1Gt(IST13830B6)Tigm/Ciz1Gt(IST13830B6)Tigm
(B6J.B6N-Ciz1Gt(IST13830B6)Tigm)
increased monocyte cell number J:231433
increased neutrophil cell number J:231433
Ciz1tm1.1Homy/Ciz1tm1.1Homy
(involves: 129P2/OlaHsd * C57BL/6 * DBA)
enlarged spleen J:198470
lymph node hyperplasia J:198470
thymus hyperplasia J:198470
Ckbtm1.1(KOMP)Wtsi/Ckbtm1.1(KOMP)Wtsi
(C57BL/6N-Ckbtm1.1(KOMP)Wtsi/Ucd)
increased lymphocyte cell number J:211773
Cks1btm1Sir/Cks1btm1Sir
Tg(IghMyc)22Bri/?

(involves: C57BL * C57BL/6 * SJL)
decreased B cell proliferation J:121564
decreased leukocyte cell number J:121564
decreased lymphocyte cell number J:121564
decreased spleen weight J:121564
Clasp1em1(IMPC)Mbp/Clasp1+
(C57BL/6NCrl-Clasp1em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Clca1tm1.1Lex/Clca1tm1.1Lex
(involves: 129S/SvEvBrd)
abnormal chemokine level J:125158
increased inflammatory response J:125158
increased neutrophil cell number J:125158
lung inflammation J:125158
Clca1tm1Dgen/Clca1tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6)
abnormal inflammatory response J:112942
Clcf1tm1.1(KOMP)Vlcg/Clcf1+
(C57BL/6N-Clcf1tm1.1(KOMP)Vlcg/Ucd)
decreased leukocyte cell number J:211773
Clcn1em1(IMPC)Mbp/Clcn1em1(IMPC)Mbp
(C57BL/6NCrl-Clcn1em1(IMPC)Mbp/MbpMmucd)
decreased leukocyte cell number J:211773
decreased monocyte cell number J:211773
Clcn2tm1Tjj/Clcn2tm1Tjj
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal microglial cell physiology J:122365
Clcn3tm1Lamb/Clcn3tm1Lamb
(involves: 129S1/Sv * 129X1/SvJ)
abnormal neutrophil physiology J:112692
impaired neutrophil phagocytosis J:112692
sepsis J:112692
Clcn3tm1Tjj/Clcn3tm1Tjj
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal microglial cell physiology J:77635
Clcn7tm1.1Lex/Clcn7tm1.1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
microgliosis J:186049
Clcn7tm1.1Mawa/Clcn7+
(involves: C57BL/6J * C57BL/6N * CD-1)
increased osteoclast cell number J:254787
Clcn7tm1.1Teti/Clcn7+
(involves: 129S2/SvPas * C57BL/6)
abnormal osteoclast physiology J:203761
increased osteoclast cell number J:203761
Clcn7tm1Tjj/Clcn7tm1Tjj
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast morphology J:67273
abnormal osteoclast physiology J:67273
Clcn7tm2Tjj/Clcn7tm2Tjj
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal osteoclast morphology J:67273, J:217031
abnormal osteoclast physiology J:67273
Clcn7tm2Tjj/Clcn7tm2Tjj
(involves: 129S1/Sv * 129X1/SvJ)
microgliosis J:155176
Clcn7tm3.1Tjj/Clcn7tm3.1Tjj
Emx1tm1.1(cre)Ito/Emx1+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6)
microgliosis J:155176
Clcn7tm4.1Tjj/Clcn7tm4.1Tjj
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal osteoclast morphology J:160702, J:217031
abnormal osteoclast physiology J:160702
Clcn7tm5.1Tjj/Clcn7tm5.1Tjj
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal osteoclast morphology J:217031
Clcnkam1Btlr/Clcnkam1Btlr
(C57BL/6J-Clcnkam1Btlr)
increased susceptibility to induced colitis J:271974
Clcnkbem1(IMPC)Mbp/Clcnkbem1(IMPC)Mbp
(C57BL/6NCrl-Clcnkbem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Cldn9em1(IMPC)H/Cldn9em1(IMPC)H
(C57BL/6NTac-Cldn9em1(IMPC)H/H)
increased basophil cell number J:211773
Cldn12tm1.1(KOMP)Vlcg/Cldn12tm1.1(KOMP)Vlcg
(B6J.B6N-Cldn12tm1.1(KOMP)Vlcg)
immune system phenotype J:279934
increased leukocyte cell number J:279934
increased spleen weight J:279934
Cldn18tm1Lex/Cldn18tm1Lex
(involves: 129S5/SvEvBrd)
abnormal osteoclast differentiation J:195931
increased osteoclast cell number J:195931
Clec1atm1Yiw/Clec1atm1Yiw
(involves: C57BL/6J * C57BL/6NSlc)
abnormal dendritic cell antigen presentation J:329240
decreased CD8-positive, alpha-beta memory T cell proliferation J:329240
decreased susceptibility to experimental autoimmune encephalomyelitis J:329240
immune system phenotype J:329240
Clec1btm1.1Arte/Clec1btm1.1Arte
Tg(Pf4-icre)Q3Rsko/0

(involves: C57BL/6)
abnormal lymphatic vessel endothelial cell morphology J:181715
abnormal lymphatic vessel morphology J:181715
Clec1btm1.1Ksi/Clec1btm1.1Ksi
(involves: C57BL/6)
abnormal lymphatic system physiology J:165898
abnormal lymphatic vessel morphology J:165898
Clec1btm1.2Arte/Clec1btm1.2Arte
(Not Specified)
abnormal lymphatic vessel morphology J:181715
decreased lymphatic vessel endothelial cell number J:181715
Clec1btm1Ksi/Clec1btm1Ksi
Tg(Pf4-icre)Q3Rsko/0

(involves: C57BL/6)
abnormal lymphatic vessel morphology J:187533
Clec1btm1Lex/Clec1btm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal mononuclear cell morphology J:161922
Clec1btm1Mlkn/Clec1btm1Mlkn
(involves: 129S4/SvJae * C57BL/6)
abnormal lymphatic vessel morphology J:162815
Clec1btm2Mlkn/Clec1btm2Mlkn
Tg(Pf4-icre)Q3Rsko/0

(involves: C57BL/6 * SJL)
lymph node hemorrhage J:205423
Clec2dtm1.1Mgil/Clec2dtm1.1Mgil
(C57BL/6-Clec2dtm1.1Mgil)
abnormal osteoclast differentiation J:143122
increased osteoclast cell number J:143122
Clec2dtm1.1Mgil/Clec2dtm1.1Mgil
(involves: C57BL/6)
immune system phenotype J:222057
Clec2htm1.1Apma/Clec2htm1.1Apma
(B6(Cg)-Clec2htm1.1Apma)
kidney inflammation J:322835
Clec2htm1.1Apma/Clec2htm1.1Apma
Rag1tm1Mom/Rag1tm1Mom

(B6.Cg-Rag1tm1Mom Clec2htm1.1Apma)
kidney inflammation J:322835
Clec4a2tm1.1Cfg/Clec4a2tm1.1Cfg
(involves: C57BL/6)
enlarged lymph nodes J:217719
immune system phenotype J:217719
increased B cell proliferation J:217719
increased IgG2a level J:217719
increased IgG2b level J:217719
increased IgG3 level J:217719
increased inflammatory response J:217719
Clec4a2tm1Yiw/Clec4a2tm1Yiw
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal circulating interleukin level J:217720
abnormal immune system morphology J:217720
abnormal immune system physiology J:217720
enthesitis J:217720
increased anti-nuclear antigen antibody level J:217720
increased autoantibody level J:217720
increased circulating interleukin-4 level J:217720
increased circulating interleukin-10 level J:217720
increased circulating interleukin-17 level J:217720
increased circulating interleukin-23 level J:217720
increased dendritic cell number J:217720
increased IgG1 level J:217720
increased IgG3 level J:217720
increased IgG level J:217720
increased inflammatory response J:217720
increased single-positive T cell number J:217720
increased susceptibility to induced arthritis J:217720
joint inflammation J:217720
salivary gland inflammation J:217720
Clec4b1em#Tsak/Clec4b1em#Tsak
(involves: C57BL/6N)
abnormal adaptive immunity J:258645
abnormal cytokine level J:258645
abnormal cytokine secretion J:258645
decreased interferon-gamma secretion J:258645
decreased interleukin-12 secretion J:258645
increased susceptibility to bacterial infection J:258645
Clec4dtm1.1Cfg/Clec4dtm1.1Cfg
(involves: C57BL/6)
decreased B cell proliferation J:217719
decreased T cell proliferation J:217719
immune system phenotype J:203221
increased B cell number J:217719
increased interferon-gamma secretion J:203221
increased interleukin-6 secretion J:203221
increased interleukin-10 secretion J:203221
increased interleukin-17 secretion J:203221
increased mature B cell number J:217719
increased susceptibility to bacterial infection J:203221
increased susceptibility to bacterial infection induced morbidity/mortality J:203221
increased tumor necrosis factor secretion J:203221
lung inflammation J:203221
Clec4dtm1.1Shoy/Clec4dtm1.1Shoy
(involves: 129P2/OlaHsd * C57BL/6)
abnormal antigen presentation J:203159
abnormal chemokine secretion J:203159
abnormal immune serum protein physiology J:203159
abnormal immune system physiology J:203159
abnormal interferon-gamma secretion J:203159
abnormal interleukin-17 secretion J:203159
abnormal response to infection J:203159
abnormal thymus morphology J:203159
decreased circulating interleukin-17 level J:203159
decreased dendritic cell number J:203159
decreased IgG level J:203159
decreased susceptibility to experimental autoimmune encephalomyelitis J:203159
decreased susceptibility to type IV hypersensitivity reaction J:203159
decreased tumor necrosis factor secretion J:203159
granulomatous inflammation J:203159
lung inflammation J:203159
Clec4etm1.1Cfg/Clec4etm1.1Cfg
(B6.Cg-Clec4etm1.1Cfg)
abnormal macrophage physiology J:136334
decreased lymphocyte cell number J:136334
decreased monocyte cell number J:136334
decreased neutrophil cell number J:136334
decreased tumor necrosis factor secretion J:136334
increased susceptibility to fungal infection J:136334
Clec4etm1Tks/Clec4etm1Tks
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal chemokine secretion J:172959
decreased interleukin-6 secretion J:172959
decreased interleukin-10 secretion J:172959
decreased neutrophil cell number J:172959
decreased susceptibility to fungal infection J:172959
decreased tumor necrosis factor secretion J:172959
Clec4etm1Tks/Clec4etm1Tks
(involves: 129S1/Sv * 129X1/SvJ)
abnormal chemokine secretion J:203159
abnormal immune serum protein physiology J:203159
abnormal interferon-gamma secretion J:203159
abnormal interleukin-17 secretion J:203159
abnormal response to infection J:203159
decreased circulating interleukin-17 level J:203159
decreased dendritic cell number J:203159
decreased IgG level J:203159
decreased susceptibility to experimental autoimmune encephalomyelitis J:203159
decreased susceptibility to type IV hypersensitivity reaction J:203159
decreased tumor necrosis factor secretion J:203159
Clec4ftm1Ymed/Clec4ftm1Ymed
(B6.129S7-Clec4ftm1Ymed)
abnormal macrophage cytokine production J:203199
decreased interferon-gamma secretion J:203199
immune system phenotype J:203199
Clec4gtm1.1Cfg/Clec4gtm1.1Cfg
(involves: C57BL/6)
increased lymphocyte cell number J:217719
increased monocyte cell number J:217719
Clec4gtm1.1Fhe/Clec4gtm1.1Fhe
(B6.129-Clec4gtm1.1Fhe)
abnormal immune system cell morphology J:200968
abnormal immune system physiology J:200968
decreased susceptibility to Adenoviridae infection J:194891
immune system phenotype J:200968
increased activated T cell number J:200968
increased CD4-positive, alpha-beta T cell number J:200968
increased CD8-positive, alpha-beta T cell number J:200968, J:194891
liver inflammation J:200968
Clec4ntm1.2Mgne/Clec4ntm1.2Mgne
(involves: C57BL/6 * C57BL/6J)
abnormal chemokine secretion J:209284
abnormal interferon secretion J:209284
abnormal interleukin secretion J:209284
abnormal macrophage physiology J:209284
abnormal neutrophil physiology J:209284
abnormal susceptibility to fungal infection J:209284
abnormal tumor necrosis factor secretion J:209284
decreased interferon-gamma secretion J:209284
decreased interleukin-17 secretion J:209284
decreased tumor necrosis factor secretion J:209284
impaired macrophage phagocytosis J:209284
impaired neutrophil phagocytosis J:209284
increased interferon-gamma secretion J:209284
increased interleukin-1 alpha secretion J:209284
increased interleukin-1 beta secretion J:209284
increased interleukin-6 secretion J:209284
increased interleukin-17 secretion J:209284
increased susceptibility to fungal infection J:209284
increased tumor necrosis factor secretion J:209284
Clec4ntm1Yiw/Clec4ntm1Yiw
(B6.129P2-Clec4ntm1Yiw)
abnormal CD4-positive T cell differentiation J:160680
decreased interferon-gamma secretion J:160680
decreased interleukin-6 secretion J:160680
decreased interleukin-10 secretion J:160680
decreased interleukin-12b secretion J:160680
decreased interleukin-17 secretion J:160680
decreased interleukin-23 secretion J:160680
decreased tumor necrosis factor secretion J:160680
increased susceptibility to infection induced morbidity/mortality J:160680
Clec4ntm1Yiw/Clec4ntm1Yiw
(involves: 129P2/OlaHsd)
increased susceptibility to fungal infection J:209284
Clec5aem1(IMPC)Mbp/Clec5aem1(IMPC)Mbp
(C57BL/6NCrl-Clec5aem1(IMPC)Mbp/MbpMmucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Clec5atm1Cua/Clec5atm1Cua
(involves: C57BL/6)
decreased susceptibility to induced arthritis J:158811
Clec7atm1.1Bpip/Clec7atm1.1Bpip
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal macrophage physiology J:203908
decreased tumor necrosis factor secretion J:203908
impaired macrophage phagocytosis J:203908
increased susceptibility to fungal infection J:203908
Clec7atm1Gdb/Clec7atm1Gdb
(involves: 129S6/SvEvTac * C57BL/6)
abnormal cytokine secretion J:116669
abnormal inflammatory response J:116669
abnormal macrophage physiology J:116669
abnormal neutrophil physiology J:116669
increased susceptibility to fungal infection J:116669
Clec7atm1Gdb/Clec7atm1Gdb
(B6.129S6-Clec7atm1Gdb)
abnormal circulating interleukin level J:179011
decreased circulating interleukin-17 level J:179011
increased susceptibility to fungal infection J:179011
lung inflammation J:179011
Clec7atm1Yiw/Clec7atm1Yiw
(C.129P2-Clec7atm1Yiw)
abnormal cytokine secretion J:116670
abnormal dendritic cell physiology J:116670
abnormal macrophage physiology J:116670
increased susceptibility to fungal infection J:116670
Clec7atm1Yiw/Clec7atm1Yiw
(involves: 129P2/OlaHsd * C57BL/6)
abnormal dendritic cell physiology J:122394
immune system phenotype J:122394
Clec7atm1Yiw/Clec7atm1Yiw
Myd88tm1Aki/Myd88tm1Aki

(involves: 129P2/OlaHsd * BALB/cA * C57BL/6J)
abnormal cytokine secretion J:116670
abnormal dendritic cell physiology J:116670
Clec9atm1.1Crs/Clec9atm1.1Crs
(C57BL/6-Clec9atm1.1Crs)
abnormal dendritic cell antigen presentation J:178441
Clec9atm1.1Kens/Clec9atm1.1Kens
(involves: C57BL/6)
abnormal humoral immune response J:181366
Clec9atm1Crs/Clec9atm1Crs
(involves: 129S6/SvEvTac * C57BL/6)
abnormal dendritic cell antigen presentation J:147472
Clec10am1/Clec10am1
(NC/Nga)
dermatitis J:283174
immune system phenotype J:283174
increased neutrophil cell number J:283174
Clec10atm1Hed/Clec10a+
St3gal1tm1Jxm/St3gal1tm1Jxm

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
decreased CD8-positive, alpha-beta T cell number J:78035
Clec10atm1Hed/Clec10atm1Hed
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
dermatitis J:283174
immune system phenotype J:78035, J:283174
increased neutrophil cell number J:283174
Clec10atm1Hed/Clec10atm1Hed
St3gal1tm1Jxm/St3gal1tm1Jxm

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
decreased CD8-positive, alpha-beta T cell number J:78035
Clec12atm1Gdb/Clec12atm1Gdb
(involves: C57BL/6)
increased susceptibility to bacterial infection J:224869
increased susceptibility to bacterial infection induced morbidity/mortality J:224869
Clec12atm1Jrld/Clec12atm1Jrld
(B6J.129-Clec12atm1Jrld)
abnormal chemokine secretion J:210326
abnormal neutrophil physiology J:210326
immune system phenotype J:210326
increased inflammatory response J:210326
increased tumor necrosis factor secretion J:210326
Clic4tm1.1Aidi/Clic4tm1.1Aidi
(involves: C57BL/6 * C57BL/6J)
abnormal chemokine secretion J:175404
decreased circulating interleukin-6 level J:175404
decreased circulating tumor necrosis factor level J:175404
decreased interleukin-6 secretion J:175404
decreased interleukin-12 secretion J:175404
decreased susceptibility to endotoxin shock J:175404
decreased tumor necrosis factor secretion J:175404
increased susceptibility to bacterial infection J:175404
Clic4tm1.1Yus/Clic4tm1.1Yus
(involves: 129S4/SvJae * C57BL/6J)
impaired macrophage phagocytosis J:183611
Clic5jbg/Clic5jbg
(involves: C3H/HeJ * C57BL/6)
decreased eosinophil cell number J:160186
decreased monocyte cell number J:160186
decreased neutrophil cell number J:160186
Clk1tm1a(EUCOMM)Wtsi/Clk1tm1a(EUCOMM)Wtsi
(C57BL/6N-Clk1tm1a(EUCOMM)Wtsi/Ics)
decreased granulocyte number J:165965
Cln3em1Dprc/Cln3em1Dprc
(C57BL/6-Cln3em1Dprc)
increased microglial cell activation J:294634
Cln3tm1Nbm/Cln3tm1Nbm
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal dendritic cell physiology J:233445
abnormal macrophage physiology J:233445
abnormal professional antigen presenting cell morphology J:233445
decreased macrophage cytokine production J:233445
Cln8em1(IMPC)Mbp/Cln8em1(IMPC)Mbp
(C57BL/6N-Cln8em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Clnkem1(IMPC)Ccpcz/Clnkem1(IMPC)Ccpcz
(C57BL/6NCrl-Clnkem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Clnktm1Rygo/Clnktm1Rygo
(B6.129P2-Clnktm1Rygo)
abnormal interferon-gamma secretion J:131738
abnormal NK T cell physiology J:131738
decreased interleukin-4 secretion J:131738
immune system phenotype J:131738
increased natural killer cell mediated cytotoxicity J:131738
Clnktm1Rygo/Clnktm1Rygo
(involves: 129P2/OlaHsd * BALB/c)
immune system phenotype J:131621
increased interferon-gamma secretion J:131621
increased natural killer cell mediated cytotoxicity J:131621
Clnktm1Rygo/Clnktm1Rygo
Lcp2tm1Geha/Lcp2tm1Geha

(involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c)
decreased interferon-gamma secretion J:131621
impaired natural killer cell mediated cytotoxicity J:131621
increased NK cell number J:131621
Clnktm1Vei/Clnktm1Vei
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal mast cell physiology J:91590
immune system phenotype J:91590
increased natural killer cell mediated cytotoxicity J:91590
Clockem1(IMPC)Ccpcz/Clockem1(IMPC)Ccpcz
(C57BL/6NCrl-Clockem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
decreased CD8-positive, naive alpha-beta T cell number J:211773
decreased effector memory T-helper cell number J:211773
decreased spleen weight J:211773
enlarged thymus J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased T-helper cell number J:211773
Clp1tm1.1Pngr/Clp1tm1.1Pngr
(CBA.Cg-Clp1tm1.1Pngr)
abnormal microglial cell morphology J:209564
ClppGt(IST11134F10)Tigm/ClppGt(IST11134F10)Tigm
(involves: C57BL/6N)
abnormal T cell activation J:203140
dermatitis J:203140
ClppGt(IST13563G11)Tigm/ClppGt(IST13563G11)Tigm
(involves: C57BL/6N)
abnormal T cell activation J:203140
dermatitis J:203140
Clpptm1a(EUCOMM)Wtsi/Clpptm1a(EUCOMM)Wtsi
(C57BL/6N-Clpptm1a(EUCOMM)Wtsi/Wtsi)
decreased CD4-positive NK T cell number J:211773
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased gamma-delta T cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
decreased NK T cell number J:211773
increased B cell number J:211773
increased KLRG1-positive NK cell number J:211773
increased leukocyte cell number J:211773
increased Ly6C high monocyte number J:211773
increased Ly6C low monocyte number J:211773
increased mature B cell number J:211773
increased monocyte cell number J:211773
Clptm1em1(IMPC)Tcp/Clptm1+
(C57BL/6NCrl-Clptm1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
Clptm1ltm1d(EUCOMM)Wtsi/Clptm1l+
(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6N)
abnormal class switch recombination J:265892
Clptm1ltm1d(EUCOMM)Wtsi/Clptm1ltm1d(EUCOMM)Wtsi
(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6N)
immune system phenotype J:265892
Clptm1ltm1d(EUCOMM)Wtsi/Clptm1ltm1d(EUCOMM)Wtsi
Prdm1tm1Nutt/Prdm1+

(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6N)
immune system phenotype J:265892
Clptq1NZB/BlNJ/Clptq1NZB/BlNJ
(B6.NZB-(D4Mit193-D4Mit33))
enlarged spleen J:143646
enlarged thymus J:143646
increased B-1a cell number J:143646
increased NK T cell number J:143646
Clrn1tm1.1(KOMP)Vlcg/Clrn1tm1.1(KOMP)Vlcg
(C57BL/6N-Clrn1tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
cls/cls
(involves: DBA/1Lac)
immune system phenotype J:15088
Clspntm1(KOMP)Vlcg/Clspn+
(C57BL/6N-Clspntm1(KOMP)Vlcg)
increased B cell number J:332163
lymphoid hyperplasia J:332163
Clstn1tm1b(EUCOMM)Hmgu/Clstn1tm1b(EUCOMM)Hmgu
(C57BL/6N-Clstn1tm1b(EUCOMM)Hmgu/H)
increased basophil cell number J:211773
Clstn3tm1b(EUCOMM)Hmgu/Clstn3tm1b(EUCOMM)Hmgu
(C57BL/6N-Clstn3tm1b(EUCOMM)Hmgu/Cnrm)
decreased spleen weight J:211773
Cltatm1.2Fmb/Cltatm1.2Fmb
(involves: C57BL/6)
abnormal class switch recombination J:235591
decreased germinal center B cell number J:235591
Clutm1Jakh/Clutm1Jakh
(involves: Black Swiss * FVB/N)
heart inflammation J:65660
myocarditis J:65660
Cluhem1(IMPC)Ccpcz/Cluh+
(C57BL/6N-Cluhem1(IMPC)Ccpcz/Ccpcz)
increased Ly6C-positive mature NK cell number J:211773
Cma1tm1Mfg/Cma1tm1Mfg
(either: (involves: 129 * C57BL/6) or (involves: 129 * BALB/c))
abnormal mast cell physiology J:98963
Cmahtm1Avrk/Cmahtm1Avrk
Dmdmdx/Dmdmdx

(involves: 129X1/SvJ * C57BL/10ScSn)
increased macrophage cell number J:164594
increased monocyte cell number J:164594
Cmahtm1Avrk/Cmahtm1Avrk
Dock2m1Hsd/Dock2m1Hsd

(B6NHsd.Cg-Dock2m1Hsd Cmahtm1Avrk)
abnormal B cell activation J:144035
decreased follicular B cell number J:144035
decreased marginal zone B cell number J:144035
Cmahtm1Avrk/Cmahtm1Avrk
Dock2m1Hsd/Dock2m1Hsd
Siaetm1.2Avrk/Siaetm1.2Avrk

(B6NHsd.Cg-Siaetm1.2Avrk Dock2m1Hsd Cmahtm1Avrk)
abnormal B cell activation J:144035
decreased follicular B cell number J:144035
decreased marginal zone B cell number J:144035
Cmahtm1Ykoz/Cmahtm1Ykoz
(B6.129P2-Cmahtm1Ykoz)
abnormal B cell physiology J:121365
abnormal humoral immune response J:121365
abnormal interleukin secretion J:121365
abnormal T cell physiology J:121365
decreased interferon-gamma secretion J:121365
immune system phenotype J:121365
increased B cell proliferation J:121365
increased IgG1 level J:121365
Cmastm1.1Bwei/Cmastm1.1Bwei
Tg(NPHS2-cre)295Lbh/0

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
tubular nephritis J:286022
CmcsCBA/N/?
(involves: CBA/N * DBA/2)
abnormal immune system physiology J:94127
CmcsDBA/2/?
(involves: CBA/N * DBA/2)
abnormal immune system physiology J:94127
Cmiptm1a(EUCOMM)Wtsi/Cmiptm1a(EUCOMM)Wtsi
(C57BL/6N-Cmiptm1a(EUCOMM)Wtsi/Wtsi)
abnormal lymphatic vessel morphology J:239583
Cmklr1tm1Dgen/Cmklr1tm1Dgen
(B6.Cg-Cmklr1tm1Dgen)
abnormal alveolar macrophage morphology J:157190
abnormal dendritic cell physiology J:157190
abnormal immune system morphology J:157190
abnormal macrophage chemotaxis J:157190
abnormal professional antigen presenting cell physiology J:157190
increased neutrophil cell number J:157190
increased susceptibility to endotoxin shock J:157190
lung inflammation J:157190
Cmklr1tm1Drg/Cmklr1tm1Drg
(Not Specified)
impaired macrophage chemotaxis J:133968
impaired neutrophil recruitment J:133968
Cms1DBA/2J/?
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to fungal infection J:55132
Cms2DBA/2J/?
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to infection J:55132
Cmtm4tm1d(EUCOMM)Wtsi/Cmtm4tm1d(EUCOMM)Wtsi
(involves: C57BL/6J * C57BL/6N)
decreased CD8-positive, alpha-beta T cell number J:333836
decreased inflammatory response J:333836
decreased susceptibility to chemically induced skin inflammation J:333836
immune system phenotype J:333836
increased B cell number J:333836
Cmtm5tm1c(KOMP)Wtsi/Cmtm5tm1c(KOMP)Wtsi
Cnptm1(cre)Kan/Cnp+

(B6.Cg-Cnptm1(cre)Kan Cmtm5tm1c(KOMP)Wtsi)
microgliosis J:327261
Cmtm7tm2a(EUCOMM)Hmgu/Cmtm7+
Rag1tm1Fwa/Rag1tm1Fwa

(chimera involves: C57BL/6 * C57BL/6N)
abnormal B cell physiology J:207033
abnormal B-1a B cell morphology J:207033
decreased B cell proliferation J:207033
decreased B-1a cell number J:207033
decreased IgG2b level J:207033
decreased IgM level J:207033
decreased plasma cell number J:207033
Cmtr1tm1b(EUCOMM)Hmgu/Cmtr1tm1b(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
Tg(Thy1-YFP)HJrs/0

(involves: 129S2/SvPas * C57BL/6J * C57BL/6N * CBA)
abnormal susceptibility to Riboviria infection J:300305
Cndp2em1(IMPC)Mbp/Cndp2em1(IMPC)Mbp
(C57BL/6NCrl-Cndp2em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Cnga3tm1.1(KOMP)Vlcg/Cnga3+
(C57BL/6N-Cnga3tm1.1(KOMP)Vlcg/Ucd)
enlarged spleen J:211773
Cngb3em1(IMPC)Ccpcz/Cngb3em1(IMPC)Ccpcz
(C57BL/6NCrl-Cngb3em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Cnmdtm1Ska/Cnmdtm1Ska
(involves: C57BL/6 * CBA)
abnormal osteoclast physiology J:81137
Cnn2tm1.1Jin/Cnn2tm1.1Jin
Cnn3tm1.1Hjum/Cnn3tm1.1Hjum
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S6/SvEvTac * 129X1/SvJ * BALB/c)
immune system phenotype J:237712
Cnn2tm1.2Jin/Cnn2tm1.2Jin
(B6.129X1-Cnn2tm1.2Jin)
abnormal immune system cell morphology J:141867
abnormal macrophage chemotaxis J:141867
abnormal macrophage physiology J:141867
decreased granulocyte number J:141867
decreased monocyte cell number J:141867
decreased neutrophil cell number J:141867
immune system phenotype J:141867
increased macrophage cell number J:141867
Cnn2tm1Jin/Cnn2tm1Jin
(B6.129X1-Cnn2tm1Jin)
decreased monocyte cell number J:141867
decreased neutrophil cell number J:141867
immune system phenotype J:141867
Cnn3tm1.1Hjum/Cnn3tm1.1Hjum
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S6/SvEvTac * BALB/c)
immune system phenotype J:237712
Cnot3tm1.1Tya/Cnot3+
(B6.129P2(Cg)-Cnot3tm1.1Tya)
abnormal osteoclast differentiation J:206802
increased osteoclast cell number J:206802
Cnot4tm1b(EUCOMM)Wtsi/Cnot4+
(C57BL/6N-Cnot4tm1b(EUCOMM)Wtsi/Wtsi)
decreased KLRG1-positive NK cell number J:211773
Cnppd1tm1.1(KOMP)Vlcg/Cnppd1tm1.1(KOMP)Vlcg
(B6N(Cg)-Cnppd1tm1.1(KOMP)Vlcg/J)
increased leukocyte cell number J:211773
Cnpy2em1(IMPC)Wtsi/Cnpy2+
(C57BL/6N-Cnpy2em1(IMPC)Wtsi/Wtsi)
increased effector memory T-helper cell number J:211773
Cnpy3tm1Kmiy/Cnpy3tm1Kmiy
(involves: C57BL/6)
abnormal lymphocyte physiology J:128513
abnormal macrophage physiology J:128513
decreased interleukin-6 secretion J:128513
decreased tumor necrosis factor secretion J:128513
Cnr2em1(IMPC)Mbp/Cnr2em1(IMPC)Mbp
(C57BL/6N-Cnr2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cnr2tm1Zim/Cnr2tm1Zim
(involves: 129 * C57BL/6)
abnormal macrophage physiology J:62417
immune system phenotype J:62417
Cntftm1Mpin/Cntftm1Mpin
(involves: 129S2/SvPas)
abnormal microglial cell morphology J:15313
Cntftm1Mpin/Cntftm1Mpin
(B6.129S2-Cntftm1Mpin)
increased susceptibility to experimental autoimmune encephalomyelitis J:126852
Cntn5em1(IMPC)Mbp/Cntn5em1(IMPC)Mbp
(C57BL/6N-Cntn5em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Coasyem1(IMPC)H/Coasy+
(C57BL/6NTac-Coasyem1(IMPC)H/H)
increased neutrophil cell number J:211773
Cobll1em1(IMPC)Ccpcz/Cobll1em1(IMPC)Ccpcz
(C57BL/6NCrl-Cobll1em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Cog5em1(IMPC)Ccpcz/Cog5+
(C57BL/6NCrl-Cog5em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cog6tm1a(EUCOMM)Wtsi/Cog6tm1a(EUCOMM)Wtsi
(C57BL/6N-Cog6tm1a(EUCOMM)Wtsi/Wtsi)
decreased alpha-beta T cell number J:211773
decreased CD4-positive NK T cell number J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased CD8-positive, naive alpha-beta T cell number J:211773
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased Ly6C-positive immature NK cell number J:211773
decreased Ly6C-positive mature NK cell number J:211773
decreased marginal zone B cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
decreased memory-marker gamma-delta T cell number J:211773
decreased memory-marker NK cell number J:211773
decreased NK cell number J:211773
decreased NK T cell number J:211773
decreased T cell number J:211773
decreased T-helper cell number J:211773
decreased transitional stage T2 B cell number J:211773
increased anti-nuclear antigen antibody level J:211773
increased B-2 B cell number J:211773
increased CD4-negative NK T cell number J:211773
increased CD4-positive, alpha-beta memory T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased CD5-positive gamma-delta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased eosinophil cell number J:211773
increased follicular B cell number J:211773
increased gamma-delta T cell number J:211773
increased granulocyte number J:211773
increased KLRG1+ CD4 alpha-beta T cell number J:211773
increased KLRG1+ CD8 alpha-beta T cell number J:211773
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased KLRG1-positive NK cell number J:211773
increased KLRG1-positive T-helper cell number J:211773
increased leukocyte cell number J:211773
increased Ly6C high monocyte number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased memory-marker gamma-delta T cell number J:211773
increased memory-marker NK cell number J:211773
increased monocyte cell number J:211773
increased plasma cell number J:211773
Col1a1Aga2/Col1a1+
(C3HeB/FeJ-Col1a1Aga2)
lung inflammation J:185988
Col1a1M1Jrt/Col1a1+
(involves: C3H/HeJ * C57BL/6J * FVB/NJ)
osteoarthritis J:216423
Col1a1M1Jrt/Col1a1+
(involves: C57BL/6 * FVB/N)
arthritis J:228439
Col1a1tm1(CAG-Ezh2*)Meln/Col1a1+
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
immune system phenotype J:199122
increased germinal center B cell number J:199122
increased spleen germinal center number J:199122
increased spleen germinal center size J:199122
Col1a1tm1(CAG-Mir22)Ppp/Col1a1tm1(CAG-Mir22)Ppp
Tg(Mx1-cre)1Cgn/0

(Not Specified)
decreased leukocyte cell number J:199366
enlarged spleen J:199366
increased myeloid dendritic cell number J:199366
Col1a1tm1(tetO-Cyp26b1)Mfra/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
abnormal lymphatic vessel morphology J:206581
Col1a1tm1(tetO-Fos)Wag/Col1a1+
Tg(KRT5-rtTA)T2D6Sgkd/0

(involves: 129S4/SvJae * C57BL/6 * FVB/N)
immune system phenotype J:201145
increased CD4-positive, alpha-beta T cell number J:201145
increased granulocyte number J:201145
skin inflammation J:201145
Col1a1tm1(tetO-GFP/RNAi:Rad21)Iaai/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
decreased B cell number J:229031
Col1a1tm1(tetO-Irf4)Sing/Col1a1tm1(tetO-Irf4)Sing
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Irf4tm1Mak/Irf4+

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal class switch recombination J:203903
abnormal plasma cell differentiation J:203903
Col1a1tm1(tetO-Irf4)Sing/Col1a1tm1(tetO-Irf4)Sing
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Irf4tm1Mak/Irf4tm1Mak

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal class switch recombination J:203903
abnormal plasma cell differentiation J:203903
Col1a1tm1(tetO-RNAi:Rps19)Karl/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae

(involves: 129S4/SvJae * C57BL/6)
decreased lymphocyte cell number J:179085
Col1a1tm1(tetO-RNAi:Rps19)Karl/Col1a1tm1(tetO-RNAi:Rps19)Karl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae

(involves: 129S4/SvJae * C57BL/6)
decreased lymphocyte cell number J:179085
decreased neutrophil cell number J:179085
Col1a1tm1(tetO-Stat1)Biat/Col1a1tm1(tetO-Stat1)Biat
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
Stat1tm1Dlv/Stat1tm1Dlv

(involves: 129S/SvEv * 129S4/SvJae * C57BL/6)
abnormal susceptibility to infection induced morbidity/mortality J:212694
Col1a1tm1(tetO-Tcfap2c)Hsc/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:174049
Col1a1tm1(tetO-Yod1*)Hpl/Col1a1tm1(tetO-Yod1*)Hpl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae

(involves: 129S4/SvJae * C57BL/6)
abnormal CD8-positive, alpha-beta T cell physiology J:194608
abnormal professional antigen presenting cell physiology J:194608
immune system phenotype J:194608
Col1a1tm1(tetO-Yod1*)Hpl/Col1a1tm1(tetO-Yod1*)Hpl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
Tap1tm1Arp/Tap1tm1Arp

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6)
abnormal professional antigen presenting cell physiology J:194608
Col1a1tm1Jae/Col1a1tm1Jae
(involves: 129S4/SvJae * C57BL/6)
abnormal osteoclast physiology J:53079
Col1a1tm2(tetO-Fosl2,-DsRed)Wag/Col1a1+
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

(involves: 129S4/SvJae * C57BL/6 * CD-1)
abnormal osteoclast morphology J:211215
Col1a1tm2(tetO-GFP/RNAi:Smc1a)Iaai/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
decreased B cell number J:229031
enlarged spleen J:229031
increased neutrophil cell number J:229031
increased spleen red pulp amount J:229031
myeloid hyperplasia J:229031
myeloid metaplasia J:229031
Col1a1tm2(tetO-GFP/RNAi:Smc1a)Iaai/Col1a1tm3(tetO-GFP/RNAi:Stag2)Iaai
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
abnormal spleen morphology J:229031
decreased B cell number J:229031
enlarged spleen J:229031
myeloid hyperplasia J:229031
Col1a1tm2(tetO-IDH2*R140Q)Ppp/Col1a1tm2(tetO-IDH2*R140Q)Ppp
Gt(ROSA)26Sortm1(rtTA*M2)Jae/?

(involves: 129S4/SvJae * C57BL/6)
enlarged spleen J:210097
Col1a1tm2(tetO-Pou5f1)Jae/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
spleen atrophy J:98920
thymus atrophy J:98920
Col1a1tm2(tetO-RNAi:Rps19)Karl/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae

(involves: 129S4/SvJae * C57BL/6)
decreased lymphocyte cell number J:179085
Col1a1tm2(tetO-RNAi:Rps19)Karl/Col1a1tm2(tetO-RNAi:Rps19)Karl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae

(involves: 129S4/SvJae * C57BL/6)
decreased lymphocyte cell number J:179085
decreased neutrophil cell number J:179085
Col1a1tm3(tetO-Fosl1,-DsRed)Wag/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
enlarged spleen J:213764
Col1a1tm3(tetO-Fosl1,-DsRed)Wag/Col1a1+
Tg(Cebpb-tTA)5Bjd/0

(involves: 129S4/SvJae * C57BL/6 * NMRI)
decreased circulating interleukin-6 level J:210545
liver inflammation J:210545
Col1a1tm3(tetO-GFP/RNAi:Stag2)Iaai/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
decreased B cell number J:229031
Col1a1tm6(tetO-MSI2)Jae/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C57BL/6)
abnormal leukocyte morphology J:163322
abnormal myelopoiesis J:163322
decreased lymphocyte cell number J:163322
decreased neutrophil cell number J:163322
enlarged spleen J:163322
increased leukocyte cell number J:163322
increased spleen weight J:163322
spleen hyperplasia J:163322
Col1a2tm1b(EUCOMM)Wtsi/Col1a2tm1b(EUCOMM)Wtsi
(C57BL/6N-Col1a2tm1b(EUCOMM)Wtsi/BayMmucd)
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased large unstained cell number J:211773
increased leukocyte cell number J:211773
increased neutrophil cell number J:211773
Col2a1tm1Prc/Col2a1+
Col9a1tm1Jae/Col9a1tm1Jae

(involves: 129/Sv * 129S2/SvPas)
osteoarthritis J:117910
Col2a1tm1Prc/Col2a1tm1Prc
(involves: 129/Sv * C57BL/6)
immune system phenotype J:30041
Col3a1m1Btlr/Col3a1m1Btlr
(C57BL/6J-Col3a1m1Btlr)
increased alpha-beta T cell number J:271973
increased CD4-positive, alpha-beta T cell number J:271973
increased CD8-positive, alpha-beta T cell number J:271973
increased susceptibility to induced colitis J:271973
Col3a1Tsk2/Col3a1+
(C3H101H-Col3a1Tsk2/H)
adipose tissue inflammation J:31216
skin inflammation J:31216
Col4a1tm1.1Ics/Col4a1+
(involves: 129S2/SvPas * C57BL/6)
kidney inflammation J:240798
Col4a1tm1.1Ics/Col4a1tm1.1Ics
(involves: 129S2/SvPas * C57BL/6)
kidney inflammation J:240798
Col4a2em1(IMPC)Wtsi/Col4a2em1(IMPC)Wtsi
(C57BL/6N-Col4a2em1(IMPC)Wtsi/WtsiOulu)
abnormal thymus topology J:239583
blood in lymph vessels J:239583
small thymus J:239583
Col4a3tm1.1Rkl/Col4a3+
(involves: C57BL/6)
glomerulonephritis J:167404
Col4a3tm1b(EUCOMM)Wtsi/Col4a3tm1b(EUCOMM)Wtsi
(C57BL/6N-Col4a3tm1b(EUCOMM)Wtsi/H)
decreased basophil cell number J:211773
decreased lymphocyte cell number J:211773
increased large unstained cell number J:211773
increased neutrophil cell number J:211773
Col4a3tm1Dec/Col4a3tm1Dec
(involves: 129X1/SvJ * C57BL/6)
glomerulonephritis J:37963
Col4a3tm1Dec/Col4a3tm1Dec
(129-Col4a3tm1Dec/J)
glomerulonephritis J:158731
Col4a3tm1Dec/Col4a3tm1Dec
(B6.129X1-Col4a3tm1Dec)
glomerulonephritis J:167404
Col4a3tm1Dec/Col4a3tm1Dec
Itga1tm1Gdnr/Itga1tm1Gdnr

(involves: 129S4/SvJae * 129X1/SvJ * BALB/c)
tubular nephritis J:71378
Col4a3tm1Dec/Col4a3tm1Dec
Sostdc1tm1Myan/Sostdc1tm1Myan

(involves: 129X1/SvJ)
glomerulonephritis J:158731
Col4a3tm1Jhm/Col4a3tm1Jhm
(involves: 129S1/Sv * 129X1/SvJ)
glomerulonephritis J:37017
Col4a3tm1Jhm/Col4a3tm1Jhm
Mmp9tm1Tvu/Mmp9tm1Tvu

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ)
glomerulonephritis J:63137
Col4a4bwk/Col4a4bwk
(NON;NZO-Col4a4bwk/J)
kidney inflammation J:223185
tubulointerstitial nephritis J:223185
Col4a4bwk/Col4a4bwk
(D2.NON(NZO)-Col4a4bwk/GrsrJ)
kidney inflammation J:223185
Col4a4bwk/Col4a4bwk
(129S1.NON(NZO)-Col4a4bwk/PgnJ)
kidney inflammation J:223185
Col4a4em1(IMPC)H/Col4a4em1(IMPC)H
(C57BL/6N-Col4a4em1(IMPC)H/H)
small thymus J:211773
Col4a4m1H/Col4a4m1H
(involves: C3H/HeH * C57BL/6J)
increased leukocyte cell number J:285510
Col4a5tm1b(EUCOMM)Wtsi/Y
(C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm)
increased leukocyte cell number J:211773
Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi
(C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm)
increased large unstained cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Col4a5tm1Yseg/Y
(B6.Cg-Col4a5tm1Yseg)
tubulointerstitial nephritis J:102306
Col6a3em1(IMPC)Tcp/Col6a3em1(IMPC)Tcp
(C57BL/6N-Col6a3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Col7a1em#Jtol/Col7a1em#Jtol
(involves: 129S4/SvJae * BALB/c * C57BL/Ka * NOD)
absent B cells J:280214
absent NK T cells J:280214
absent T cells J:280214
Col9a1tm1Jae/Col9a1tm1Jae
(either: (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL))
osteoarthritis J:18628
Col9a1tm1Jae/Col9a1tm1Jae
(involves: 129S2/SvPas)
osteoarthritis J:117910
Col9a3em1(IMPC)Tcp/Col9a3em1(IMPC)Tcp
(C57BL/6N-Col9a3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Col10a1tm1.1Rpbh/Col10a1tm1.1Rpbh
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased osteoclast cell number J:154052
Col10a1tm1Bhr/Col10a1tm1Bhr
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal spleen morphology J:62230
absent lymph nodes J:62230
decreased B cell number J:62230
decreased double-positive T cell number J:62230
decreased spleen red pulp amount J:62230
decreased spleen weight J:62230
decreased thymocyte number J:62230
decreased thymus weight J:62230
increased CD4-positive, alpha-beta T cell number J:62230
increased double-negative T cell number J:62230
increased single-positive T cell number J:62230
small spleen J:62230
small thymus J:62230
spleen hypoplasia J:62230
thymus hypoplasia J:62230
Col10a1tm1Ksec/Col10a1tm1Ksec
(involves: 129S/SvEv * C57BL/6)
abnormal T-helper 2 cell differentiation J:193886
decreased dendritic cell number J:193886
decreased interleukin-2 secretion J:193886
decreased interleukin-4 secretion J:193886
decreased interleukin-10 secretion J:193886
decreased interleukin-17 secretion J:193886
increased B cell number J:193886
increased interleukin-4 secretion J:193886
increased T-helper cell number J:193886
Col11a1cho/Col11a1+
(involves: C57BL/6Fr)
osteoarthritis J:106282
Col13a1tm1Pih/Col13a1tm1Pih
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J))
myositis J:71939
Col17a1tm1.1(COL17A1)Zliu/Col17a1tm1.1(COL17A1)Zliu
(involves: 129P2/OlaHsd * C57BL/6J)
increased mast cell degranulation J:261781
increased neutrophil cell number J:261781
Col17a1tm1Shzu/Col17a1tm1Shzu
Tg(KRT14-COL17A1)1Shzu/0

(involves: 129S/SvEv * C57BL/6J * C57BL/6Ncr)
decreased autoantibody level J:121695
Col17a1tm1Tiin/Col17a1tm1Tiin
(involves: C57BL/6)
increased autoantibody level J:220622
increased basophil cell number J:220622
increased eosinophil cell number J:220622
increased IgE level J:220622
increased monocyte cell number J:220622
increased neutrophil cell number J:220622
skin inflammation J:220622
Col26a1em3(IMPC)Tcp/Col26a1em3(IMPC)Tcp
(C57BL/6NCrl-Col26a1em3(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Col27a1em1(IMPC)Mbp/Col27a1+
(C57BL/6N-Col27a1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Colec11tm1Lex/Colec11tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal complement protein level J:234934
Colec12em1(IMPC)Mbp/Colec12em1(IMPC)Mbp
(C57BL/6N-Colec12em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Colgalt2tm1.1Hwei/Colgalt2tm1.1Hwei
(involves: C57BL/6J)
abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:310468
abnormal regulatory T cell morphology J:310468
increased circulating interleukin-1 beta level J:310468
increased circulating interleukin-4 level J:310468
increased circulating interleukin-6 level J:310468
increased circulating interleukin-9 level J:310468
increased T cell apoptosis J:310468
Commd8tm1.1Ksuz/Commd8tm1.1Ksuz
Ightm1Mnz/Igh+
Cd79atm1(cre)Reth/Cd79a+

(involves: 129P2/OlaHsd * BALB/c * C57BL/6NSlc * SJL)
abnormal spleen B cell follicle morphology J:278399
Commd9tm1b(KOMP)Wtsi/Commd9+
(C57BL/6N-Commd9tm1b(KOMP)Wtsi/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Commd10Tg(Vav1-icre)A2Kio/0
Map3k7tm1.1Arte/Map3k7tm1.1Arte

(involves: C57BL/10 * C57BL/6J * C57BL/6NTac * CBA/Ca)
decreased interleukin-6 secretion J:332172
decreased interleukin-10 secretion J:332172
decreased interleukin-12b secretion J:332172
decreased macrophage cell number J:332172
decreased tumor necrosis factor secretion J:332172
enlarged axillary lymph nodes J:332172
enlarged inguinal lymph nodes J:332172
enlarged spleen J:332172
increased B cell number J:332172
increased lymphocyte cell number J:332172
increased neutrophil cell number J:332172
increased splenocyte number J:332172
Commd10Tg(Vav1-icre)A2Kio/0
Nfil3tm1.2Kubo/Nfil3tm1.2Kubo

(involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca)
decreased dendritic cell number J:334296
Commd10Tg(Vav1-icre)A2Kio/?
Tnfrsf14tm1.1Kro/Tnfrsf14tm1.1Kro

(involves: C57BL/6NCrl * C57BL/10 * CBA * SJL)
decreased susceptibility to Herpesvirales infection J:243038
Comptm1Mbri/Comptm1Mbri
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
osteoarthritis J:125086
Comttm1Kara/Comttm1Kara
(involves: 129S4/SvJaeSor)
increased interferon-gamma secretion J:137276
increased uterine NK cell number J:137276
Copatm1.1Shum/Copa+
(B6(CBA)-Copatm1.1Shum)
abnormal B cell morphology J:288425
abnormal T cell activation J:288425
bronchiolitis J:288425
decreased double-positive T cell number J:288425
increased effector memory T-helper cell number J:288425
increased single-positive T cell number J:288425
lung inflammation J:288425
Copg1em1Geha/Copg1em1Geha
(involves: C57BL/6)
abnormal B cell physiology J:345528
abnormal IgG level J:345528
decreased circulating interferon-gamma level J:345528
immune system phenotype J:345528
increased susceptibility to bacterial infection induced morbidity/mortality J:345528
increased T cell apoptosis J:345528
Cops5tm1Rpar/Cops5tm1Rpar
Tg(Lck-cre)548Jxm/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL)
decreased double-positive T cell number J:132114
decreased single-positive T cell number J:132114
decreased thymocyte number J:132114
increased T cell apoptosis J:132114
thymus medulla hypoplasia J:132114
Cops5tm1Rpar/Cops5tm1Rpar
Tg(Lck-cre)548Jxm/0
Tg(TcraTcrb)425Cbn/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL)
decreased thymocyte number J:132114
Cops5tm1Rpar/Cops5tm1Rpar
Tg(Lck-cre)548Jxm/0
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129 * C57BL/6 * CBA * SJL)
decreased thymocyte number J:132114
Cops6Gt(RRI087)Byg/Cops6+
(involves: 129P2/OlaHsd * C57BL/6J)
increased thymocyte apoptosis J:172038
Cops7atm1b(KOMP)Mbp/Cops7atm1b(KOMP)Mbp
(C57BL/6N-Cops7atm1b(KOMP)Mbp/Ucd)
increased monocyte cell number J:211773
Cops8tm1Nwe/Cops8tm1.1Nwe
Tg(Cd4-cre)1Cwi/?

(involves: 129S1/Sv * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:126339
abnormal T cell activation J:126339
decreased interleukin-2 secretion J:126339
decreased T cell number J:126339
decreased T cell proliferation J:126339
Cora1BALB/c/Cora1BALB/c
(involves: BALB/c * STS/A)
abnormal cytokine secretion J:52119
Cora1STS/A/Cora1STS/A
(involves: BALB/c * STS/A)
abnormal cytokine secretion J:52119
Coro1akoy/Coro1akoy
(C57BL/6-Coro1akoy)
abnormal T cell physiology J:141431
decreased CD4-positive, alpha-beta T cell number J:141431
decreased CD8-positive, alpha-beta T cell number J:141431
decreased thymocyte number J:141431
Coro1aLmb3-C57BL/6Scr/Coro1aLmb3-C57BL/6Scr
(MRL.Cg-Coro1aC57BL/6Scr Faslpr)
decreased autoantibody level J:125557
decreased spleen weight J:125557
decreased susceptibility to systemic lupus erythematosus J:125557
glomerulonephritis J:125557
small lymph nodes J:125557
Coro1aLmb3-MRL/MpScr/Coro1aLmb3-MRL/MpScr
(involves: C57BL/6-Faslpr * MRL-Faslpr)
enlarged lymph nodes J:45708
enlarged spleen J:45708
Coro1aLmb3-MRL/MpScr/Coro1aLmb3-MRL/MpScr
(B6.MRL-Coro1aMRL/MpScr Faslpr)
enlarged lymph nodes J:125557
increased spleen weight J:125557
increased susceptibility to systemic lupus erythematosus J:125557
Coro1aptcd/Coro1aptcd
(B6.CTS-Coro1aptcd)
abnormal effector T cell morphology J:141431
abnormal T cell activation J:141431
abnormal T cell physiology J:141431
decreased CD4-positive, alpha-beta T cell number J:141431
decreased CD8-positive, alpha-beta T cell number J:141431
increased T cell apoptosis J:141431
increased thymocyte number J:141431
Coro1aptcd/Coro1atm1Achn
(B6.Cg-Coro1aptcd Coro1atm1Achn)
abnormal effector T cell morphology J:141431
abnormal T cell activation J:141431
abnormal T cell physiology J:141431
decreased CD4-positive, alpha-beta T cell number J:141431
decreased CD8-positive, alpha-beta T cell number J:141431
increased thymocyte number J:141431
Coro1atm1Achn/Coro1atm1Achn
(involves: 129X1/SvJ * C57BL/6)
abnormal leukocyte migration J:111593
decreased CD4-positive, alpha-beta T cell number J:111593
decreased CD8-positive, alpha-beta T cell number J:111593
decreased memory T cell number J:111593
decreased T cell number J:111593
Coro1atm1Achn/Coro1atm1Achn
(B6.129X1-Coro1atm1Achn)
decreased thymocyte number J:141431
increased T cell apoptosis J:141431
Coro1atm1Achn/Coro1atm1Achn
(involves: 129X1/SvJ)
decreased interleukin-6 secretion J:177785
decreased tumor necrosis factor secretion J:177785
increased mast cell degranulation J:177785
Coro1atm1Achn/Coro1atm1Achn
Coro1btm1.1Nfoe/Coro1btm1.1Nfoe

(involves: 129X1/SvJ * C57BL/6N)
decreased interleukin-6 secretion J:177785
decreased tumor necrosis factor secretion J:177785
increased mast cell degranulation J:177785
increased susceptibility to type I hypersensitivity reaction J:177785
Coro1atm1Jpie/Coro1atm1Jpie
(involves: 129 * C57BL/6)
abnormal T cell activation J:133258
abnormal thymocyte activation J:133258
decreased B cell number J:133258
decreased CD4-positive, alpha-beta T cell number J:133258
decreased CD8-positive, alpha-beta T cell number J:133258
decreased interleukin-2 secretion J:133258
decreased monocyte cell number J:133258
decreased susceptibility to bacterial infection J:133404
decreased T cell proliferation J:133258
impaired macrophage phagocytosis J:133404
Coro1btm1.1Nfoe/Coro1btm1.1Nfoe
(B6N.129X1-Coro1btm1.1Nfoe)
immune system phenotype J:177785
Coro1ctm1a(KOMP)Wtsi/Coro1ctm1a(KOMP)Wtsi
(C57BL/6N-Coro1ctm1a(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
Cotl1tm1b(EUCOMM)Hmgu/Cotl1tm1b(EUCOMM)Hmgu
(C57BL/6N-Cotl1tm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Cox4i2tm1Hutt/Cox4i2+
(B6.129-Cox4i2tm1Hutt)
lung inflammation J:187640
Cox4i2tm1Hutt/Cox4i2tm1Hutt
(B6.129-Cox4i2tm1Hutt)
immune system phenotype J:233986
lung inflammation J:187640
Cox6b1em1(IMPC)Tcp/Cox6b1+
(C57BL/6NCrl-Cox6b1em1(IMPC)Tcp/Tcp)
increased spleen weight J:211773
Cox10tm1Ctm/Cox10tm1Ctm
Slc6a3tm1.1(cre)Bkmn/?

(B6.Cg-Cox10tm1Ctm Slc6a3tm1.1(cre)Bkmn)
abnormal chemokine secretion J:231810
increased interleukin-1 beta secretion J:231810
increased microglial cell activation J:231810
microgliosis J:231810
Cox19tm1b(EUCOMM)Hmgu/Cox19+
(C57BL/6N-Cox19tm1b(EUCOMM)Hmgu/Tcp)
enlarged lymph nodes J:211773
Cptm1Hrs/Cptm1Hrs
(involves: 129X1/SvJ * Black Swiss)
increased spleen iron level J:57730
Cptm1Hrs/Cptm1Hrs
Hephsla/Y

(involves: 129X1/SvJ * C57BL/6)
eye inflammation J:136925
Cptm1Yos/Cptm1Yos
(involves: 129P2/OlaHsd * BALB/c)
abnormal Kupffer cell morphology J:79916
Cpa1tm1.1Satom/Cpa1tm1.1Satom
(involves: C57BL/6NCrl * FVB/N)
pancreas inflammation J:300042
Cpa3tm1Hrr/Cpa3tm1Hrr
(involves: 129P2/OlaHsd * C57BL/6)
abnormal mast cell morphology J:99367
Cpa3tm3(icre)Hrr/Cpa3+
(B6.129P2-Cpa3tm3(icre)Hrr)
abnormal inflammatory response J:178942
absent mast cells J:178942
decreased basophil cell number J:178942
immune system phenotype J:178942
Cpa3tm3(icre)Hrr/Cpa3+
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
decreased susceptibility to type I hypersensitivity reaction J:178942
Cpa3tm3(icre)Hrr/Cpa3+
Fgfr1tm1Upir/Fgfr1tm1Upir
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(KRT5-cre)5132Jlj/0

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J)
absent mast cells J:221184
skin inflammation J:221184
Cpa3tm3(icre)Hrr/Cpa3+
Gt(ROSA)26Sortm1Hjf/?
Notch1tm1Agt/Notch1tm1Agt

(involves: 129 * C57BL/6)
abnormal dendritic cell differentiation J:143731
abnormal T cell receptor beta chain V(D)J recombination J:143731
Cpa3tm3(icre)Hrr/Cpa3+
Notch1tm1Agt/Notch1tm1Agt

(involves: 129 * C57BL/6)
abnormal B cell differentiation J:143731
abnormal B cell morphology J:143731
abnormal T cell receptor beta chain V(D)J recombination J:143731
decreased double-negative T cell number J:143731
decreased double-positive T cell number J:143731
increased single-positive T cell number J:143731
thymus hypoplasia J:143731
Cpb2tm1Efp/Cpb2+
Plgtm1Dco/Plg+

(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6)
abnormal inflammatory response J:80114
Cpb2tm1Efp/Cpb2tm1Efp
Plgtm1Dco/Plg+

(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6)
abnormal inflammatory response J:80114
Cpb2tm1Mng/Cpb2tm1Mng
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal chemokine level J:107340
abnormal tumor necrosis factor level J:107340
Cpb2tm1Nok/Cpb2tm1Nok
(involves: 129P2/OlaHsd * BALB/c)
impaired complement alternative pathway J:93733
increased inflammatory response J:93733
Cpetm1b(EUCOMM)Hmgu/Cpetm1b(EUCOMM)Hmgu
(C57BL/6N-Cpetm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Cpgi5563tm1.1(NCC)Wcs/Cpgi5563tm1.1(NCC)Wcs
(C57BL/6N-Cpgi5563tm1.1(NCC)Wcs/Wtsi)
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:277622
decreased CD8-positive, alpha-beta T cell number J:277622
decreased effector memory CD4-positive, alpha-beta T cell number J:277622
decreased gamma-delta T cell number J:277622
Cplane2b2b2827Clo/Cplane2b2b2827Clo
(C57BL/6J-Cplane2b2b2827Clo)
thymus hypoplasia J:175213
Cpmem1(IMPC)Ccpcz/Cpmem1(IMPC)Ccpcz
(C57BL/6NCrl-Cpmem1(IMPC)Ccpcz/Ccpcz)
decreased CD8-positive, alpha-beta T cell number J:211773
immune system phenotype J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
Cpn1tm1Raw/Cpn1tm1Raw
(B6.129S1-Cpn1tm1Raw)
abnormal complement pathway J:148315
increased acute inflammation J:148315
Cpne5tm2b(EUCOMM)Hmgu/Cpne5tm2b(EUCOMM)Hmgu
(C57BL/6N-Cpne5tm2b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
CpoxRbc16/Cpox+
(involves: C57BL/6)
enlarged spleen J:244493
increased spleen red pulp amount J:244493
Cpqem1(IMPC)Tcp/Cpqem1(IMPC)Tcp
(C57BL/6N-Cpqem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Cps1em1(IMPC)H/Cps1+
(C57BL/6NTac-Cps1em1(IMPC)H/H)
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Cpsf6em1Bcgen/Cpsf6+
(Not Specified)
decreased susceptibility to Riboviria infection J:346988
increased interferon-beta secretion J:346988
Cpt1cGt(XL823)Byg/Cpt1c+
Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
spleen hyperplasia J:228258
Cpt2tm1b(KOMP)Wtsi/Cpt2tm1b(KOMP)Wtsi
(C57BL/6N-Cpt2tm1b(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
Cpvlem1(IMPC)Tcp/Cpvlem1(IMPC)Tcp
(C57BL/6NCrl-Cpvlem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Cpxm1em1(IMPC)Tcp/Cpxm1em1(IMPC)Tcp
(C57BL/6N-Cpxm1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
Cr1ltm1.1Song/Cr1ltm1.1Song
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL)
decreased CD4-positive, alpha-beta T cell number J:146538
decreased CD8-positive, alpha-beta T cell number J:146538
decreased lymphocyte cell number J:146538
increased B cell number J:146538
lymph node hypoplasia J:146538
Cr1ltm1.1Song/Cr1ltm1.1Song
Tg(Lck-cre)548Jxm/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL)
decreased CD4-positive, alpha-beta T cell number J:146538
decreased CD8-positive, alpha-beta T cell number J:146538
decreased lymphocyte cell number J:146538
increased B cell number J:146538
lymph node hypoplasia J:146538
Cr1ltm1.1Song/Cr1ltm1.1Song
Vsig4tm1Gne/Vsig4tm1Gne
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6N * DBA/2 * SJL)
decreased lymphocyte cell number J:146538
Cr1ltm1Hmo/Cr1ltm1Hmo
(involves: 129X1/SvJ)
increased inflammatory response J:59432
Cr2M1Btlr/Cr2M1Btlr
(C57BL/6J-Cr2M1Btlr)
decreased IgG level J:267527
impaired humoral immune response J:267527
Cr2tm1.1Jhws/Cr2tm1.1Jhws
(B6.Cg-Cr2tm1.1Jhws)
immune system phenotype J:155241
Cr2tm1.1Jhws/Cr2tm1.1Jhws
(Not Specified)
abnormal germinal center B cell physiology J:205353
decreased B-1a cell number J:205353
decreased IgG2b level J:205353
decreased IgG2c level J:205353
decreased IgG3 level J:205353
decreased IgM level J:205353
immune system phenotype J:205353
increased susceptibility to bacterial infection induced morbidity/mortality J:205353
Cr2tm1Crr/Cr2tm1Crr
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal B-1 B cell morphology J:31942
abnormal humoral immune response J:31942, J:69452
abnormal immune system morphology J:69452
abnormal spleen germinal center morphology J:31942
decreased B cell number J:31942
decreased B-1a cell number J:69452
decreased IgG2a level J:31942
decreased IgG2b level J:31942
decreased IgG3 level J:31942
decreased IgG level J:31942, J:69452
decreased IgM level J:69452
decreased immunoglobulin level J:69452
decreased neutrophil cell number J:66111
decreased spleen germinal center number J:31942, J:69452
decreased spleen germinal center size J:31942
decreased tumor necrosis factor secretion J:66111
immune system phenotype J:31942
Cr2tm1Crr/Cr2tm1Crr
(involves: 129S7/SvEvBrd * C57BL/6J)
increased anti-double stranded DNA antibody level J:111811
Cr2tm1Crr/Cr2tm1Crr
(involves: 129S7/SvEvBrd)
decreased follicular B cell number J:69477
increased marginal zone B cell number J:69477
Cr2tm1Crr/Cr2tm1Crr
Ggta1tm1Jbl/Ggta1tm1Jbl

(involves: 129S2/SvPas * 129S7/SvEvBrd)
abnormal humoral immune response J:113488
Cr2tm1Hmo/Cr2tm1Hmo
(involves: 129S7/SvEvBrd)
decreased IgG level J:35112
decreased IgM level J:35112
Cr2tm1Hmo/Cr2tm1Hmo
(B6.129S7-Cr2tm1Hmo)
increased susceptibility to bacterial infection J:94855
Cr2tm1Hmo/Cr2tm1Hmo
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal B cell activation J:151991
abnormal B cell physiology J:151991
abnormal class switch recombination J:151991
abnormal memory B cell differentiation J:151991
Cr2tm1Tft/Cr2tm1Tft
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal adaptive immunity J:95979
decreased IgG1 level J:95979
decreased IgG2b level J:95979
decreased IgG3 level J:95979
decreased IgG level J:95979
decreased IgM level J:95979
decreased spleen germinal center number J:95979
increased susceptibility to bacterial infection J:95979
Cr2tm2.1(HLA-A)Crr/Cr2tm2.1(HLA-A)Crr
(involves: C57BL/6)
abnormal B cell physiology J:151991
abnormal class switch recombination J:151991
abnormal memory B cell differentiation J:151991
Cr2tm2.1(HLA-A)Crr/Cr2tm2.1(HLA-A)Crr
Tg(IghelMD4)4Ccg/?

(involves: C57BL/6)
abnormal B cell activation J:151991
Cr2tm2.1Jhws/Cr2tm2.1Jhws
(B6.129-Cr2tm2.1Jhws)
abnormal germinal center B cell physiology J:205353
decreased IgG3 level J:205353
decreased IgM level J:205353
immune system phenotype J:205353
increased IgM level J:205353
Crabp1tm1b(EUCOMM)Wtsi/Crabp1tm1b(EUCOMM)Wtsi
(C57BL/6N-Crabp1tm1b(EUCOMM)Wtsi/Tcp)
increased monocyte cell number J:211773
Cracr2atm1.1Ygwa/Cracr2atm1.1Ygwa
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Cracr2atm1.1Ygwa Tg(Cd4-cre)1Cwi)
abnormal CD4-positive, alpha-beta T cell physiology J:259523
decreased interleukin-2 secretion J:259523
Crb1rd8+em1Boc/Crb1rd8+em1Boc
Jak3m1J/Jak3m1J

(B6.Cg-Crb1rd8+em1Boc Jak3m1J/Boc)
small spleen J:265859
small thymus J:265859
Crb1rd8/Crb1rd8
Jak3m1J/Jak3m1J

(B6.Cg-Crb1rd8 Jak3m1J/BocJ)
decreased spleen weight J:265859
small spleen J:265859
small thymus J:265859
Crbntm1.1Ble/Crbntm1.1Ble
(involves: C57BL/6)
decreased B cell number J:267091
decreased granulocyte number J:267091
decreased leukocyte cell number J:267091
decreased T cell number J:267091
Creb3l3tm1.1Sad/Creb3l3tm1.1Sad
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
decreased acute inflammation J:140018
decreased circulating serum amyloid protein level J:140018
CrebbpGt(U-San)112Imeg/Crebbp+
(involves: C57BL/6 * CBA)
abnormal tumor necrosis factor level J:75361
Crebbptm1Dli/Crebbp+
(involves: 129S6/SvEvTac * C57BL/6)
abnormal granulocyte morphology J:191503
abnormal leukocyte morphology J:191503
absent pre-B cells J:60630
decreased B cell number J:60630
decreased lymphocyte cell number J:191503
enlarged spleen J:191503, J:60630
increased granulocyte number J:191503
Crebbptm1Jvd/Crebbptm1Jvd
Ep300tm2Pkb/Ep300tm2Pkb
Tg(Lck-cre)548Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal T cell number J:105505
decreased double-positive T cell number J:105505
increased double-negative T cell number J:105505
Crebbptm1Jvd/Crebbptm1Jvd
Tg(Lck-cre)548Jxm/0

(involves: 129 * C57BL/6 * CBA)
decreased CD4-positive, alpha-beta T cell number J:105505
decreased T cell number J:105505
decreased thymocyte number J:105505
increased double-positive T cell number J:105505
small thymus J:105505
Crebbptm1Jvd/Crebbptm1Jvd
Tg(MMTV-cre)4Mam/0

(involves: 129 * C57BL/6 * FVB)
decreased double-positive T cell number J:88323
increased CD8-positive, alpha-beta T cell number J:88323
Crebbptm1Pkb/Crebbptm1Pkb
(involves: 129P2/OlaHsd * C57BL/6)
decreased thymocyte number J:98329
Crhtm1Maj/Crhtm1Maj
(involves: 129S2/SvPas * C57BL/6)
abnormal cell-mediated immunity J:98419
abnormal cytokine secretion J:98419
abnormal inflammatory response J:98419
abnormal professional antigen presenting cell physiology J:98419
decreased inflammatory response J:90690, J:72196
decreased susceptibility to experimental autoimmune encephalomyelitis J:98419
decreased T cell proliferation J:98419
increased circulating interleukin-6 level J:72196
increased splenocyte number J:98419
Crhr2tm1Mpsp/Crhr2tm1Mpsp
(involves: 129X1/SvJ * C57BL/6J)
immune system phenotype J:61510
cri/cri
(involves: DBA/2J)
decreased leukocyte cell number J:6327
decreased neutrophil cell number J:6327
Crim1em1(IMPC)Wtsi/Crim1em1(IMPC)Wtsi
(C57BL/6N-Crim1em1(IMPC)Wtsi/WtsiOrl)
absent connection between subcutaneous lymph vessels and lymph sac J:239583
blood in lymph vessels J:239583
Crim1Gt(KST264)Byg/Crim1Gt(KST264)Byg
(involves: 129P2/OlaHsd * C57BL/6 * CD-1)
kidney inflammation J:172334
Crip3tm1Mjb/Crip3tm1Mjb
(either: (involves: 129S/Sv) or (involves: 129S/Sv * C57BL/6))
decreased thymocyte number J:72942
small thymus J:72942
thymus hypoplasia J:72942
Crispld2tm1Lex/Crispld2tm1Lex
(B6;129S5-Crispld2tm1Lex/Mmucd)
abnormal immune system morphology J:171883
abnormal immune system physiology J:171883
Crkltm1Imo/Crkltm1Imo
(involves: 129S4/SvJaeSor * C57BL/6J)
abnormal thymus development J:67826
Crl1A/WySnJ/Crl1A/WySnJ
(B10.A-H2a/SgSnJ)
abnormal B cell physiology J:5442
Crl1AKR/J/Crl1AKR/J
(involves: AKR/J * DBA/2J)
abnormal B cell physiology J:5442
Crl1DBA/2J/Crl1DBA/2J
(involves: AKR/J * DBA/2J)
abnormal B cell physiology J:5442
Crlf2em1(IMPC)Mbp/Crlf2em1(IMPC)Mbp
(C57BL/6N-Crlf2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Crlf2tm1Jni/Crlf2tm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:89031
Crlf2tm1Jni/Crlf2tm1Jni
(involves: 129P2/OlaHsd)
respiratory system inflammation J:187770
Crlf2tm1Wjl/Crlf2tm1Wjl
(involves: 129 * C57BL/6)
abnormal lymphopoiesis J:108209
decreased B cell number J:108209
decreased single-positive T cell number J:108209
Crlf2tm1Wjl/Crlf2tm1Wjl
(involves: BALB/c)
abnormal cytokine secretion J:107431
abnormal T cell proliferation J:107431
decreased immunoglobulin level J:107431
decreased splenocyte proliferation J:107431
lung inflammation J:107431
Crlf2tm1Wjl/Crlf2tm1Wjl
(Not Specified)
colitis J:175844
Crmp1em1(IMPC)Mbp/Crmp1em1(IMPC)Mbp
(C57BL/6NCrl-Crmp1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Crocctm1Tili/Crocctm1Tili
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
lung inflammation J:98885
Crotem1Akw/Crotem1Akw
Ldlrtm1Her/Ldlrtm1Her

(B6.Cg-Crotem1Akw Ldlrtm1Her)
blood vessel inflammation J:331161
Crptm1Hjf/Crp+
(C57BL/6-Crptm1Hjf)
decreased circulating C-reactive protein level J:170409
Crptm1Hjf/Crptm1Hjf
(C57BL/6-Crptm1Hjf)
decreased circulating C-reactive protein level J:170409
Crppaem1(IMPC)H/Crppa+
(C57BL/6NTac-Crppaem1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Crsl/Crsl+
(involves: C3HeB/FeJ)
keratoconjunctivitis sicca J:104123
Crtamtm1Achn/Crtamtm1Achn
(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:145314
abnormal interleukin secretion J:145314
abnormal T cell activation J:145314
abnormal T-helper 1 physiology J:145314
decreased interferon-gamma secretion J:145314
decreased interleukin-17 secretion J:145314
increased CD4-positive, alpha-beta T cell number J:145314
increased CD8-positive, alpha-beta T cell number J:145314
increased susceptibility to bacterial infection J:145314
increased T cell proliferation J:145314
Crtamtm1Tks/Crtamtm1Tks
(B6.Cg-Crtamtm1Tks)
abnormal response to infection J:152770
immune system phenotype J:152770
Crtc1tm1a(EUCOMM)Wtsi/Crtc1+
(C57BL/6N-Crtc1tm1a(EUCOMM)Wtsi/Ics)
increased IgG2b level J:165965
Crxem1(IMPC)Ccpcz/Crxem1(IMPC)Ccpcz
(C57BL/6N-Crxem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased NK cell number J:211773
small thymus J:211773
Cry1tm1Jhjh/Cry1tm1Jhjh
Cry2tm1Jhjh/Cry2tm1Jhjh

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell activation J:159504
increased circulating interleukin-1 beta level J:159504
increased circulating interleukin-6 level J:159504
increased circulating tumor necrosis factor level J:159504
increased susceptibility to induced arthritis J:159504
increased tumor necrosis factor secretion J:159504
Cry2tm1Jhjh/Cry2tm1Jhjh
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast physiology J:163112
Csf1op/Csf1op
(C57BL/6J-Csf1op)
abnormal osteoclast morphology J:5634
abnormal spleen red pulp morphology J:5634
decreased macrophage cell number J:110981
decreased osteoclast cell number J:5634
Csf1op/Csf1op
(B6C3Fe a/a-Csf1op/J)
abnormal Kupffer cell morphology J:26978
abnormal Langerhans cell morphology J:112594
abnormal Langerhans cell physiology J:112594
abnormal microglial cell morphology J:49613
abnormal osteoclast differentiation J:19549, J:4732
abnormal osteoclast morphology J:26978
abnormal perivascular macrophage morphology J:49613
abnormal spleen red pulp morphology J:26978
abnormal splenic cell ratio J:104139
abnormal splenocyte physiology J:19549
absent Langerhans cell J:112594
decreased leukocyte cell number J:104139
decreased macrophage cell number J:26978, J:104139
decreased monocyte cell number J:104139
decreased osteoclast cell number J:73663
thymus cortex hypoplasia J:26978
thymus medulla atrophy J:26978
Csf1op/Csf1op
(involves: C3HeB/FeJ * C57BL/6J)
abnormal osteoclast cell number J:33189
abnormal osteoclast differentiation J:38039
decreased osteoclast cell number J:33189
Csf1op/Csf1op
(B6;C3Fe a/a-Csf1op/J)
abnormal microglial cell morphology J:170081
decreased macrophage cell number J:30863, J:147697
impaired macrophage chemotaxis J:147697
Csf1op/Csf1op
Csf2tm1Ard/Csf2tm1Ard

(involves: 129P2/OlaHsd * C57BL/6)
decreased leukocyte cell number J:19089
increased neutrophil cell number J:19089
interstitial pneumonia J:19089
lung inflammation J:19089
Csf1op/Csf1op
Galctwi/Galctwi

(involves: C3HeB/Fe * C57BL/6J * CE/J)
impaired macrophage chemotaxis J:170081
Csf1op/Csf1op
Mpztm1Msch/Mpz+

(involves: 129S7/SvEvBrd * C57BL/6)
immune system phenotype J:67581
Csf1op/Csf1op
Sh3bp2tm1Bjro/Sh3bp2tm1Bjro

(involves: 129S4/SvJae * BALB/cJ * C57BL/6J)
abnormal lymph node cell ratio J:117880
increased circulating tumor necrosis factor level J:117880
liver inflammation J:117880
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Tg(SIRPA)1Flv/0
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv

(involves: 129S4/SvJae * BALB/cAnNTac)
abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv

(involves: 129S4/SvJae * BALB/cAnNTac)
abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Tg(SIRPA)1Flv/0
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv

(involves: 129S4/SvJae * BALB/cAnNTac)
abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv

(involves: 129S4/SvJae * BALB/cAnNTac)
abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv

(involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * BALB/cAnNTac)
abnormal immune system physiology J:177073
immune system phenotype J:177073
Csf1tm1.2Sabw/Csf1tm1.2Sabw
(involves: 129S4/SvJaeSor * C57BL/6)
abnormal Kupffer cell morphology J:180199
abnormal myeloid leukocyte morphology J:180199
decreased B cell number J:180199
decreased lymphocyte cell number J:180199
decreased macrophage cell number J:180199
decreased monocyte cell number J:180199
decreased osteoclast cell number J:180199
decreased spleen weight J:180199
increased granulocyte number J:180199
increased T cell number J:180199
small spleen J:180199
Csf1rtm1Ers/Csf1r+
(B6.129X1-Csf1rtm1Ers)
microgliosis J:219294
Csf1rtm1Ers/Csf1rtm1Ers
(involves: 129X1/SvJ * C3Heb/FeJ * C57BL/6J)
abnormal circulating cytokine level J:73663
abnormal leukocyte cell number J:73663
abnormal osteoclast differentiation J:73663
abnormal spleen morphology J:73663
decreased Langerhans cell number J:73663
decreased lymphocyte cell number J:73663
decreased macrophage cell number J:73663
decreased monocyte cell number J:73663
increased granulocyte number J:73663
increased spleen weight J:73663
Csf1rtm1Ers/Csf1rtm1Ers
(FVB.129X1-Csf1rtm1Ers)
abnormal Langerhans cell physiology J:112594
abnormal macrophage differentiation J:112594
abnormal osteoclast morphology J:111489
absent Langerhans cell J:112594
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv

(involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac)
abnormal response to transplant J:168302
Csf2tm1Ard/Csf2tm1Ard
(involves: 129P2/OlaHsd * C57BL/6)
abnormal alveolar macrophage morphology J:18747
abnormal leukocyte physiology J:86386
abnormal MHC II cell surface expression on macrophages J:86386
abnormal spleen size J:67766
impaired macrophage chemotaxis J:86386
increased susceptibility to bacterial infection J:18747, J:53659
increased susceptibility to fungal infection J:18747
increased susceptibility to parasitic infection J:67766
lung inflammation J:18747
lymphoid hyperplasia J:18747
Csf2tm1Dran/Csf2tm1Dran
Ifngtm1Ts/Ifngtm1Ts
Il3tm1Glli/Il3tm1Glli

(involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6)
increased eosinophil cell number J:83086
increased IgE level J:83086
increased IgG1 level J:83086
increased immunoglobulin level J:83086
increased inflammatory response J:83086
Csf2tm1Dran/Csf2tm1Dran
Il3tm1Glli/Il3tm1Glli

(B6.129S2-Csf2tm1Dran Il3tm1Glli)
abnormal leukocyte physiology J:83086
decreased susceptibility to type IV hypersensitivity reaction J:67404
glomerulonephritis J:83086
increased anti-double stranded DNA antibody level J:83086
increased eosinophil cell number J:67404
lung inflammation J:67404
Csf2tm1Dran/Csf2tm1Dran
Il3tm1Glli/Il3tm1Glli

(C.129S2-Csf2tm1Dran Il3tm1Glli)
decreased susceptibility to type IV hypersensitivity reaction J:67404
increased eosinophil cell number J:67404
lung inflammation J:67404
Csf2tm1Mlg/Csf2tm1Mlg
(involves: 129S2/SvPas)
abnormal alveolar macrophage morphology J:17978
decreased susceptibility to experimental autoimmune encephalomyelitis J:148120
lymphoid hyperplasia J:17978
Csf2raem1Szut/Csf2raem1Szut
(C57BL/6-Csf2raem1Szut)
abnormal alveolar macrophage morphology J:322934
impaired macrophage phagocytosis J:322934
increased lymphocyte cell number J:322934
lung inflammation J:322934
Csf2rbtm1Cgb/Csf2rbtm1Cgb
(involves: 129S1/Sv * C57BL/6)
decreased eosinophil cell number J:29737
lung inflammation J:29737
Csf2rbtm1Clsc/Csf2rbtm1Clsc
Csf2rb2tm1Cgb/Csf2rb2tm1Cgb

(C.129S1-Csf2rb2tm1Cgb Csf2rbtm1Clsc)
abnormal dendritic cell physiology J:130939
abnormal interleukin secretion J:130939
abnormal plasmacytoid dendritic cell physiology J:130939
abnormal T cell activation J:130939
abnormal T cell physiology J:130939
decreased interleukin-4 secretion J:130939
decreased interleukin-5 secretion J:130939
decreased interleukin-13 secretion J:130939
decreased susceptibility to type I hypersensitivity reaction J:130939
decreased T cell proliferation J:130939
impaired eosinophil recruitment J:130939
increased IgG1 level J:130939
lymph node hyperplasia J:130939
Csf2rbtm1Mur/Csf2rbtm1Mur
(involves: 129P2/OlaHsd * C57BL/6)
abnormal eosinophil physiology J:35829
decreased eosinophil cell number J:35829
lung inflammation J:35829
Csf2rbtm1Mur/Csf2rbtm1Mur
(involves: 129P2/OlaHsd)
abnormal eosinophil physiology J:24122
decreased eosinophil cell number J:24122
increased susceptibility to infection J:24122
lung inflammation J:24122
Csf2rbtm1Mur/Csf2rbtm1Mur
Il3tm1Tyb/Il3tm1Tyb

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
abnormal eosinophil physiology J:35829
decreased eosinophil cell number J:35829
lung inflammation J:35829
Csf2rbtm2b(EUCOMM)Hmgu/Csf2rb+
(C57BL/6N-Csf2rbtm2b(EUCOMM)Hmgu/Orl)
increased eosinophil cell number J:211773
Csf3em1(IMPC)H/Csf3em1(IMPC)H
(C57BL/6NTac-Csf3em1(IMPC)H/H)
decreased eosinophil cell number J:211773
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Csf3tm1Ard/Csf3+
(involves: 129P2/OlaHsd * C57BL/6)
decreased neutrophil cell number J:20400
Csf3tm1Ard/Csf3tm1Ard
(involves: 129P2/OlaHsd * C57BL/6)
abnormal neutrophil physiology J:20400
decreased leukocyte cell number J:20400
decreased monocyte cell number J:20400
decreased neutrophil cell number J:20400
impaired myelopoiesis J:20400
increased susceptibility to bacterial infection J:20400
Csf3tm1Ard/Csf3tm1Ard
Junbtm3Wag/Junbtm3Wag
Tg(KRT5-cre)1Tak/0

(involves: 129/Sv * 129P2/OlaHsd * C3H * C57BL/6)
increased susceptibility to systemic lupus erythematosus J:155575
Csf3rtm1Eur/Csf3rtm1Eur
(involves: 129P2/OlaHsd * C57BL/6 * FVB)
abnormal neutrophil differentiation J:48503
decreased neutrophil cell number J:48503
Csf3rtm1Link/Csf3rtm1Link
(involves: 129X1/SvJ * NIH Black Swiss)
abnormal monocyte morphology J:37618
decreased monocyte cell number J:37618
decreased neutrophil cell number J:37618
Csf3rtm1Link/Csf3rtm1Link
(involves: 129X1/SvJ)
impaired neutrophil chemotaxis J:79825
Csf3rtm1Link/Csf3rtm1Link
(B6.129X1-Csf3rtm1Link)
impaired neutrophil chemotaxis J:79567
Csf3rtm2Eur/Csf3rtm2Eur
(involves: 129P2/OlaHsd * FVB)
decreased neutrophil cell number J:185115
Csf3rtm2Link/Csf3r+
Elanetm1Link/Elane+

(involves: 129X1/SvJ * C57BL/6)
immune system phenotype J:131496
Csf3rtm2Link/Csf3rtm2Link
(B6.129X1-Csf3rtm2Link)
abnormal neutrophil physiology J:79567
Csf3rtm3Link/Csf3rtm3Link
(B6.129X1-Csf3rtm3Link)
immune system phenotype J:79567
Csf3rtm3Link/Csf3rtm3Link
(involves: 129X1/SvJ * C57BL/6)
decreased neutrophil cell number J:67612
Csf3rtm4(Epor)Link/Csf3rtm4(Epor)Link
(involves: 129X1/SvJ * C57BL/6)
decreased granulocyte number J:79825
decreased neutrophil cell number J:79825
impaired neutrophil chemotaxis J:79825
Csf3rtm4(Epor)Link/Csf3rtm4(Epor)Link
(B6.129X1-Csf3rtm4(Epor)Link)
decreased neutrophil cell number J:79567
impaired neutrophil chemotaxis J:79567
Csgalnact1tm1.1Migar/Csgalnact1tm1.1Migar
(involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj)
periodontium inflammation J:269621
Csktm1Sor/Csk+
Ptprcltng/Ptprcltng

(involves: 129S7/SvEvBrd * C57BL/6)
thymus hypoplasia J:158876
Csktm1Sor/Csk+
Ptprcltng/Ptprctm1Mak

(involves: 129S7/SvEvBrd * C57BL/6)
abnormal T cell differentiation J:158876
thymus hypoplasia J:158876
Csktm1Tara/Csktm1Tara
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CB20 * CBA)
abnormal CD4-positive T cell differentiation J:49654
absent CD8-positive, alpha-beta T cells J:49654
enlarged thymus J:49654
Csktm1Tara/Csktm2Tara
Elanetm1(cre)Roes/Elane+

(involves: 129P2/OlaHsd * CB20 * C57BL/6)
abnormal granulocyte physiology J:89716
abnormal myelopoiesis J:89716
increased acute inflammation J:89716
increased susceptibility to bacterial infection J:89716
Csmd3em1(IMPC)Mbp/Csmd3em1(IMPC)Mbp
(C57BL/6NCrl-Csmd3em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
Csnk1a1tm1c(KOMP)Wtsi/Csnk1a1tm1c(KOMP)Wtsi
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * C57BL/6N * CBA)
abnormal spleen red pulp morphology J:216977
bone marrow failure J:216977
Csnk1g1em1(IMPC)J/Csnk1g1em1(IMPC)J
(C57BL/6NJ-Csnk1g1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Csnk2a2em1(IMPC)Mbp/Csnk2a2em1(IMPC)Mbp
(C57BL/6N-Csnk2a2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Cspg4tm1Wbst/Cspg4tm1Wbst
(involves: 129S1/Sv * 129X1/SvJ)
abnormal macrophage physiology J:184220
CsptC57BL/6/CsptC57BL/6
(involves: C57BL/6 * NOD/ShLtDoi * SJL)
increased CD8-positive, alpha-beta T cell number J:97046
CsptC57BL/6/CsptNOD/ShiLtDoi
(involves: C57BL/6 * NOD/ShLtDoi * SJL)
increased CD8-positive, alpha-beta T cell number J:97046
Csrnp1tm1Jni/Csrnp1tm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:129366
Csrnp1tm1Jni/Csrnp1tm1Jni
Csrnp2tm1Jni/Csrnp2tm1Jni

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:129366
Csrnp2tm1Jni/Csrnp2tm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:129366
Csrnp3tm1Jni/Csrnp3tm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:129366
Cst6em1(IMPC)Ccpcz/Cst6+
(C57BL/6NCrl-Cst6em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Cstbtm1b(EUCOMM)Wtsi/Cstbtm1b(EUCOMM)Wtsi
(C57BL/6N-Cstbtm1b(EUCOMM)Wtsi/Orl)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Cstbtm1Rm/Cstbtm1Rm
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
increased incidence of corneal inflammation J:50587
uveitis J:50587
Ct55em1Xdzg/Ct55em1Xdzg
(involves: C57BL/6)
decreased susceptibility to induced colitis J:280149
Ctbstm1Tbec/Ctbstm1Tbec
(involves: 129S2/SvPas * C57BL/6N)
abnormal Kupffer cell morphology J:185162
Ctc1tm1.1Schg/Ctc1tm1.1Schg
(involves: 129S7/SvEvBrd * C57BL/6)
decreased splenocyte proliferation J:184809
small spleen J:184809
small thymus J:184809
Ctcftm2Gal/Ctcf+
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:143271
decreased CD8-positive, alpha-beta T cell number J:143271
thymus hypoplasia J:143271
Ctcftm2Gal/Ctcftm2Gal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * C57BL/10)
decreased double-positive T cell number J:143271
Ctcftm2Gal/Ctcftm2Gal
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:143271
abnormal T cell morphology J:143271
decreased CD4-positive, alpha-beta T cell number J:143271
decreased CD8-positive, alpha-beta T cell number J:143271
decreased double-positive T cell number J:143271
decreased single-positive T cell number J:143271
increased double-negative T cell number J:143271
increased single-positive T cell number J:143271
thymus hypoplasia J:143271
Ctcftm2Gal/Ctcftm2Gal
Tg(Lck-cre)1Cwi/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * DBA/2J)
abnormal T cell differentiation J:143271
decreased CD4-positive, alpha-beta T cell number J:143271
decreased CD8-positive, alpha-beta T cell number J:143271
decreased double-positive T cell number J:143271
Ctcftm2Gal/Ctcftm2Gal
Tg(Lck-cre)1Cwi/0
Tg(TcraTcrb)425Cbn/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:143271
decreased CD4-positive, alpha-beta T cell number J:143271
decreased double-positive T cell number J:143271
decreased T cell number J:143271
increased double-negative T cell number J:143271
increased single-positive T cell number J:143271
Ctdspl2tm2b(KOMP)Wtsi/Ctdspl2+
(C57BL/6N-Ctdspl2tm2b(KOMP)Wtsi/Bay)
increased spleen weight J:211773
ctl/ctl
(A/WySnJ-ctl/GrsrJ)
arthritis J:91389
Ctl1NZB/BlN/Ctl1C57BL/10
(involves: C57BL/10 * NZB/BlN)
abnormal T cell physiology J:6736
Ctla4m1Btlr/Ctla4m1Btlr
(C57BL/6J-Ctla4m1Btlr)
decreased CD8-positive, naive alpha-beta T cell number J:265263
increased effector memory CD4-positive, alpha-beta T cell number J:265263
increased effector memory CD8-positive, alpha-beta T cell number J:265263
Ctla4tm1All/Ctla4tm1All
(involves: 129S1/Sv * 129X1/SvJ)
abnormal thymus morphology J:42481
decreased double-positive T cell number J:42481
decreased T cell number J:42481
increased double-negative T cell number J:42481
lymph node hypoplasia J:42481
Ctla4tm1All/Ctla4tm1All
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * NOD)
increased acute inflammation J:109887
Ctla4tm1All/Ctla4tm1All
Rag1tm1Mom/Rag1tm1Mom
Tg(TcrAND)53Hed/0

(involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL)
abnormal T cell activation J:119845
increased interleukin-4 secretion J:119845
increased T cell proliferation J:119845
Ctla4tm1All/Ctla4tm1All
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraTcrb)8Rest/0

(involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6)
immune system phenotype J:140448
Ctla4tm1All/Ctla4tm1All
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * NOD * SJL)
abnormal splenocyte physiology J:109887
enlarged spleen J:109887
increased acute inflammation J:109887
insulitis J:109887
Ctla4tm1All/Ctla4tm1All
Tg(TcrAND)53Hed/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
abnormal lymphopoiesis J:119845
abnormal T cell activation J:119845
abnormal T cell subpopulation ratio J:119845
increased CD4-positive, alpha-beta T cell number J:119845
increased CD8-positive, alpha-beta T cell number J:119845
Ctla4tm1All/Ctla4tm1All
Tg(TcraTcrb)8Rest/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:140448
increased CD4-positive, alpha-beta T cell number J:140448
increased interferon-gamma secretion J:140448
Ctla4tm1Mak/Ctla4tm1Mak
(involves: 129P2/OlaHsd * BALB/c)
increased interferon-gamma secretion J:140085
increased interleukin-2 secretion J:140085
increased interleukin-4 secretion J:140085
increased interleukin-17 secretion J:140085
Ctla4tm1Saka/Ctla4tm1Saka
Foxp3tm1(cre)Saka/Y

(involves: BALB/c)
abnormal immunoglobulin level J:140085
abnormal regulatory T cell physiology J:140085
abnormal splenic cell ratio J:140085
increased autoantibody level J:140085
increased IgE level J:140085
increased IgG level J:140085
increased inflammatory response J:140085
increased interferon-gamma secretion J:140085
increased interleukin-2 secretion J:140085
increased interleukin-4 secretion J:140085
increased regulatory T cell number J:140085
lung inflammation J:140085
lymph node hyperplasia J:140085
myocarditis J:140085
salivary gland inflammation J:140085
spleen hyperplasia J:140085
stomach inflammation J:140085
Ctla4tm1Shr/Ctla4tm1Shr
(either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6))
abnormal cytokine secretion J:30393
abnormal lymph node cell ratio J:30393
abnormal splenic cell ratio J:30393
abnormal T cell differentiation J:30393
abnormal T cell morphology J:30393
decreased double-positive T cell number J:30393
enlarged lymph nodes J:30393
enlarged spleen J:30393
increased double-negative T cell number J:30393
increased T cell number J:30393
increased T cell proliferation J:30393
joint inflammation J:30393
lung inflammation J:30393
myocarditis J:30393
pancreas inflammation J:30393
salivary gland inflammation J:30393
Ctla4tm1Shr/Ctla4tm1Shr
(B6.129S4-Ctla4tm1Shr)
abnormal regulatory T cell physiology J:146644
abnormal T cell physiology J:146644
autoimmune response J:146644
Ctla4tm1Shr/Ctla4tm1Shr
Rag2tm1Fwa/Rag2tm1Fwa
Tg(DO11.10)10Dlo/0

(involves: 129S/Sv * BALB/c * C3H * C57BL/6)
abnormal cytokine secretion J:110446
abnormal T cell physiology J:110446
immune system phenotype J:110446
Ctla4tm1Shr/Ctla4tm1Shr
Tg(DO11.10)10Dlo/0

(involves: 129S4/SvJae * BALB/c * C3H * C57BL/6)
abnormal T cell physiology J:57090
enlarged lymph nodes J:57090
enlarged spleen J:57090
increased T cell proliferation J:57090
Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cervical lymph node morphology J:71744
abnormal macrophage physiology J:71744
abnormal peripheral lymph node morphology J:71744
absent peripheral lymph nodes J:71744
absent Peyer's patches J:71744
absent popliteal lymph nodes J:71744
conjunctivitis J:71744
decreased Peyer's patch number J:71744
increased granulocyte number J:71744
increased inflammatory response J:71744
increased leukocyte cell number J:71744
increased susceptibility to otitis media J:71744
increased susceptibility to parasitic infection J:71744
keratoconjunctivitis sicca J:71744
small axillary lymph nodes J:71744
small brachial lymph nodes J:71744
small Peyer's patches J:71744
Ctnnb1tm1Mmt/Ctnnb1+
Ctsktm1(cre)Ska/Ctsk+

(involves: 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj)
abnormal osteoclast differentiation J:178340
Ctnnb1tm1Mmt/Ctnnb1+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129X1/SvJ)
abnormal osteoclast differentiation J:178340
Ctnnb1tm1Mmt/Ctnnb1+
Ppargtm1.1(tTA)Jmgr/Pparg+
Tg(tetO-cre)1Jaw/0

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6)
abnormal osteoclast differentiation J:178340
decreased osteoclast cell number J:178340
increased splenocyte number J:178340
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Col1a1-cre)1Kry/0

(involves: 129X1/SvJ * FVB)
decreased osteoclast cell number J:98430
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

(involves: 129X1/SvJ * CD-1)
abnormal osteoclast differentiation J:114494
Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+
Tg(CMV-cre)1Cgn/0

(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal lymph node morphology J:71744
abnormal macrophage physiology J:71744
abnormal Peyer's patch morphology J:71744
increased granulocyte number J:71744
increased inflammatory response J:71744
increased leukocyte cell number J:71744
increased susceptibility to otitis media J:71744
keratoconjunctivitis sicca J:71744
Ctnnb1tm2Kem/Ctnnb1+
Ctsktm1(cre)Ska/Ctsk+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj)
increased osteoclast cell number J:178340
Ctnnb1tm2Kem/Ctnnb1+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
increased osteoclast cell number J:178340
Ctnnb1tm2Kem/Ctnnb1+
Ppargtm1.1(tTA)Jmgr/Pparg+
Tg(tetO-cre)1Jaw/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal osteoclast physiology J:178340
increased osteoclast cell number J:178340
Ctnnb1tm2Kem/Ctnnb1+
Tg(Tek-cre)1Ywa/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
increased osteoclast cell number J:178340
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Ctsktm1(cre)Ska/Ctsk+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj)
increased osteoclast cell number J:178340
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
increased osteoclast cell number J:178340
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Ppargtm1.1(tTA)Jmgr/Pparg+
Tg(tetO-cre)1Jaw/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal osteoclast physiology J:178340
decreased osteoclast cell number J:178340
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Ppargtm1.1(tTA)Jmgr/Pparg+
Tg(tetO-cre)1Jaw/0
Tg(tetO-HIST1H2BJ/GFP)47Efu/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1)
abnormal osteoclast differentiation J:178340
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Col1a1-cre)1Kry/0

(involves: 129S1/Sv * 129X1/SvJ * FVB)
increased osteoclast cell number J:98430
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(KRT14-cre/ERT)20Efu/0

(involves: 129S1/Sv * 129X1/SvJ * CD-1)
cutaneous mastocytosis J:204142
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Tek-cre)1Ywa/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
decreased osteoclast cell number J:178340
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Krt14tm1(cre)Wbm/Krt14+

(involves: 129P2/OlaHsd)
decreased gamma-delta T cell number J:202499
increased neutrophil cell number J:202499
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Tg(Pdx1-cre)6Tuv/0

(involves: 129P2/OlaHsd * FVB/N)
pancreas inflammation J:119908
Ctps1em1(IMPC)Tcp/Ctps1+
(C57BL/6N-Ctps1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Ctrb1em1Toth/Ctrb1em1Toth
(C57BL/6N-Ctrb1em1Toth)
increased susceptibility to induced pancreatitis J:294171, J:294035
Ctrcm1/Ctrcm1
(C57BL/6-Ctrcm1)
increased susceptibility to induced pancreatitis J:291240
Ctrq1C3H/HeJ/Ctrq1C3H/HeJ
(involves: C3H/HeJ * C57BL/6J)
increased susceptibility to bacterial infection J:106111
Ctrq2C3H/HeJ/Ctrq2C3H/HeJ
(involves: C3H/HeJ * C57BL/6J)
decreased susceptibility to bacterial infection J:106111
Ctrq2C3H/HeJ/Ctrq2C57BL/6J
(involves: C3H/HeJ * C57BL/6J)
decreased susceptibility to bacterial infection J:106111
Ctrq3C3H/HeJ/Ctrq3C3H/HeJ
(involves: C3H/HeJ * C57BL/6J)
increased susceptibility to bacterial infection J:106111
Ctrq3C3H/HeJ/Ctrq3C57BL/6J
(involves: C3H/HeJ * C57BL/6J)
increased susceptibility to bacterial infection J:106111
Ctsatm1Adz/Ctsatm1Adz
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/NJ))
enlarged spleen J:29674
Ctsatm2b(EUCOMM)Hmgu/Ctsatm2b(EUCOMM)Hmgu
(C57BL/6N-Ctsatm2b(EUCOMM)Hmgu/H)
enlarged spleen J:211773
increased monocyte cell number J:211773
increased spleen weight J:211773
Ctsbtm1Jde/Ctsb+
(NOD.129P2-Ctsbtm1Jde)
decreased susceptibility to autoimmune diabetes J:153355
insulitis J:153355
Ctsbtm1Jde/Ctsbtm1Jde
(either: (involves: 129P2/OlaHsd * 129/Sv) or (involves: 129P2/OlaHsd * C57BL/6))
immune system phenotype J:47432
Ctsbtm1Jde/Ctsbtm1Jde
(NOD.129P2-Ctsbtm1Jde)
decreased susceptibility to autoimmune diabetes J:153355
insulitis J:153355
salivary gland inflammation J:153355
Ctsbtm1Jde/Ctsbtm1Jde
Serpina3gtm1.1Arp/Serpina3gtm1.1Arp

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:189782
Ctsctm1Ley/Ctsctm1Ley
(either: 129X1/SvJ-Ctsctm1Ley or (involves: 129X1/SvJ * C57BL/6))
abnormal cytotoxic T cell physiology J:77312
abnormal T cell physiology J:77312
Ctsctm1Ley/Ctsctm1Ley
(B6.129X1-Ctsctm1Ley)
abnormal chemokine level J:131520
abnormal leukocyte migration J:131520
abnormal response to infection J:131520
decreased circulating interleukin-6 level J:131520
impaired neutrophil recruitment J:131520
increased circulating interleukin-6 level J:88160
sepsis J:88160
Ctsctm1Ley/Ctsctm1Ley
Il6tm1Kopf/Il6tm1Kopf

(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6)
immune system phenotype J:88160
Ctsdm1J/Ctsdm1J
(C3HeB/FeJ-Ctsdm1J/GrsrJ)
thymus atrophy J:229377
Ctsdtm1.1Thre/Ctsdtm1.1Thre
Edil3Tg(Sox2-cre)1Amc/Edil3+

(involves: C57BL/6 * C57BL/6N * CBA * SJL)
decreased double-positive T cell number J:227618
microgliosis J:227618
thymus atrophy J:227618
Ctsdtm1.1Thre/Ctsdtm1.1Thre
Tg(Nes-cre)1Kln/0

(involves: C57BL/6 * C57BL/6N * SJL)
abnormal thymus morphology J:227618
decreased double-positive T cell number J:227618
microgliosis J:227618
Ctsdtm1Cptr/Ctsdtm1Cptr
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd))
abnormal antigen presentation J:47432
abnormal microglial cell morphology J:71688
abnormal spleen B cell follicle morphology J:28201
abnormal spleen white pulp morphology J:28201
decreased double-positive T cell number J:28201
decreased lymphocyte cell number J:28201
thymus hypoplasia J:28201
CtseC57BL/6JOlaHsd/CtseC57BL/6JOlaHsd
(involves: 129S2/SvPasHsd * C57BL/6JOlaHsd)
abnormal dendritic cell antigen presentation J:128538
abnormal dendritic cell physiology J:128538
abnormal immune system physiology J:128538
Ctsetm1Kjy/Ctse+
(involves: C57BL/6)
increased IgE level J:108745
Ctsetm1Kjy/Ctsetm1Kjy
(involves: C57BL/6)
dermatitis J:108745
increased circulating interleukin-1 beta level J:108745
increased circulating interleukin-18 level J:108745
increased double-positive T cell number J:108745
increased eosinophil cell number J:108745
increased IgE level J:108745
increased interleukin-4 secretion J:108745
increased interleukin-5 secretion J:108745
Ctsgtm1.1Roes/Ctsgtm1.1Roes
(involves: 129P2/OlaHsd)
decreased susceptibility to bacterial infection induced morbidity/mortality J:77597
increased susceptibility to infection induced morbidity/mortality J:77597
Ctsgtm1.1Roes/Ctsgtm1.1Roes
Elanetm1(cre)Roes/Elanetm1(cre)Roes

(involves: 129P2/OlaHsd)
decreased susceptibility to endotoxin shock J:77597
increased susceptibility to fungal infection J:77597
Ctsgtm1Ley/Ctsgtm1Ley
(either: (involves: 129X1/SvJ * C57BL/6) or (involves: 129X1/SvJ))
immune system phenotype J:59006
Ctsgtm1Ley/Ctsgtm1Ley
Elanetm1Sds/Elanetm1Sds

(involves: 129X1/SvJ)
immune system phenotype J:131496
Ctsgtm1Ley/Ctsgtm1Ley
Elanetm1Sds/Elanetm1Sds

(B6.129X1-Elanetm1Sds Ctsgtm1Ley)
immune system phenotype J:131520
Ctsgtm2.1(PML/RARA)Ley/Ctsg+
(involves: 129X1/SvJ * C57BL/6)
abnormal myelopoiesis J:84230, J:86458
enlarged spleen J:84230
increased leukocyte cell number J:84230
Ctsgtm2.1(PML/RARA)Ley/Ctsg+
(involves: 129 * 129X1/SvJ * C57BL/6)
abnormal spleen morphology J:166479
enlarged spleen J:166479
increased spleen weight J:166479
Ctsgtm2.1(PML/RARA)Ley/Ctsg+
Elanetm1Sds/Elanetm1Sds

(involves: 129S/SvEv * 129X1/SvJ * C57BL/6)
abnormal myelopoiesis J:86458
Ctsgtm3.1(PML/RARA)Ley/Ctsg+
(involves: 129 * C57BL/6)
abnormal spleen morphology J:166479
enlarged spleen J:166479
increased spleen weight J:166479
Ctsktm1(cre)Ska/Ctsk+
Esr1tm1Mma/Esr1tm1Mma

(involves: 129S2/SvPas * C57BL/6 * SJL)
abnormal osteoclast physiology J:127179
increased osteoclast cell number J:127179
Ctsktm1(cre)Ska/Ctsk+
Plekhm1tm1.1Hzhao/Plekhm1tm1.1Hzhao

(involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj)
abnormal osteoclast morphology J:236517
abnormal osteoclast physiology J:236517
Ctsktm1(cre)Ska/Ctsk+
Snx10tm1c(EUCOMM)Raba/Snx10tm1c(EUCOMM)Raba

(involves: 129S4/SvJae * C57BL/6 * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj)
abnormal osteoclast physiology J:224711
Ctsktm1.1Rbar/Ctsktm1.1Rbar
Tg(Itgam-cre)AJva/0

(involves: C57BL/6)
increased osteoclast cell number J:194492
Ctsktm1.1Rbar/Ctsktm1.1Rbar
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal osteoclast differentiation J:194492
abnormal osteoclast physiology J:194492
increased osteoclast cell number J:194492
Ctsktm1Mbs/Ctsktm1Mbs
(B6.129-Ctsktm1Mbs)
abnormal osteoclast physiology J:128098
increased osteoclast cell number J:128098
Ctsktm1Psa/Ctsktm1Psa
(involves: 129X1/SvJ * C57BL/6J)
abnormal osteoclast physiology J:50934
Ctsktm1Vuo/Ctsktm1Vuo
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal osteoclast morphology J:95525
increased osteoclast cell number J:95525
Ctsktm1Ypl/Ctsktm1Ypl
(B6.129S4-Ctsktm1Ypl)
increased osteoclast cell number J:117870
Ctsktm1Ypl/Ctsktm1Ypl
(129S4/SvJae-Ctsktm1Ypl)
increased osteoclast cell number J:117870
Ctslm1Btlr/Ctslm1Btlr
(C57BL/6J-Ctslm1Btlr)
abnormal CD4-positive T cell differentiation J:272869
abnormal CD8-positive, alpha beta T cell morphology J:272869
abnormal CD8-positive, alpha-beta T cell differentiation J:272869
abnormal T cell differentiation J:272869
decreased alpha-beta T cell number J:272869
decreased CD4-positive, alpha-beta T cell number J:272869
increased alpha-beta T cell number J:272869
increased CD8-positive, alpha-beta T cell number J:272869
increased central memory CD4-positive, alpha-beta T cell number J:272869
increased central memory CD8 positive, alpha-beta T cell number J:272869
increased effector memory CD4-positive, alpha-beta T cell number J:272869
Ctslnkt/Ctslnkt
(either: (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL/6) or (involves: 129S2/SvPas * DBA/2))
abnormal immune system organ morphology J:54856
decreased CD4-positive, alpha-beta T cell number J:54856
dermatitis J:54856
increased inflammatory response J:54856
liver inflammation J:54856
lymph node hyperplasia J:54856
lymph node inflammation J:54856
thymus atrophy J:54856
Ctslnkt/Ctslnkt
(B6.Cg-Ctslnkt)
dermatitis J:78460
enlarged lymph nodes J:78460
Ctslnkt/Ctslnkt
(C.Cg-Ctslnkt)
abnormal immune system organ morphology J:78460
abnormal leukocyte cell number J:99009
abnormal lymph node cortex morphology J:99009
abnormal lymph node morphology J:99009
abnormal thymus corticomedullary boundary morphology J:99009
abnormal thymus lobule morphology J:99009
abnormal thymus morphology J:99009
decreased CD4-positive, alpha-beta T cell number J:99009
dermatitis J:78460
dilated lymph node medullary sinus J:99009
enlarged lymph nodes J:78460, J:99009
enlarged thymus cortex J:99009
increased CD8-positive, alpha-beta T cell number J:99009
Ctsltm1.2Thre/Ctsltm1.2Thre
(involves: C57BL/6 * C57BL/6N)
decreased CD4-positive, alpha-beta T cell number J:216506
Ctsltm1Alpk/Ctsltm1Alpk
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast physiology J:99755
decreased osteoclast cell number J:99755
dermatitis J:99755
folliculitis J:99755
granulomatous inflammation J:99755
Ctsltm1Alpk/Ctsltm1Alpk
(B6.129P2-Ctsltm1Alpk)
granulomatous inflammation J:99755
Ctsltm1Cptr/Ctsl+
(NOD.129P2-Ctsltm1Cptr)
decreased susceptibility to autoimmune diabetes J:153355
insulitis J:153355
Ctsltm1Cptr/Ctsltm1Cptr
(involves: 129P2/OlaHsd * C57BL/6J)
increased regulatory T cell number J:153355
Ctsltm1Cptr/Ctsltm1Cptr
(NOD.129P2-Ctsltm1Cptr)
decreased CD4-positive, alpha-beta T cell number J:153355
decreased susceptibility to autoimmune diabetes J:153355
increased regulatory T cell number J:153355
salivary gland inflammation J:153355
Ctsltm1Cptr/Ctsltm1Cptr
(involves: 129P2/OlaHsd)
decreased CD4-positive, alpha-beta T cell number J:216506
Ctsmtm1(KOMP)Wtsi/Ctsmtm1(KOMP)Wtsi
(C57BL/6N-Ctsmtm1(KOMP)Wtsi/Nju)
increased monocyte cell number J:211773
Ctssem1(IMPC)H/Ctssem1(IMPC)H
(C57BL/6NTac-Ctssem1(IMPC)H/H)
decreased spleen weight J:211773
Ctssm1Btlr/Ctssm1Btlr
(C57BL/6J-Ctssm1Btlr)
decreased IgG level J:267491
impaired humoral immune response J:267491
Ctsstm1Eae/Ctss+
(NOD.D1-Ctsstm1Eae)
insulitis J:153355
Ctsstm1Eae/Ctsstm1Eae
(involves: C57BL/6 * DBA/1LacJ)
abnormal B lymphocyte antigen presentation J:53399
decreased susceptibility to induced arthritis J:53399
Ctsstm1Eae/Ctsstm1Eae
(NOD.D1-Ctsstm1Eae)
decreased susceptibility to autoimmune diabetes J:153355
insulitis J:153355
salivary gland inflammation J:153355
Ctsstm1Hap/Ctsstm1Hap
(B6.129S2-Ctsstm1Hap)
abnormal B cell physiology J:96401
abnormal cytokine secretion J:96401
abnormal humoral immune response J:96401
abnormal interleukin secretion J:96401
abnormal professional antigen presenting cell physiology J:96401
abnormal T cell physiology J:96401
decreased IgG level J:96401
decreased IgM level J:96401
decreased susceptibility to experimental autoimmune myasthenia gravis J:96401
Ctsstm1Hap/Ctsstm1Hap
Ldlrtm1Her/Ldlrtm1Her

(B6.129S-Ctsstm1Hap Ldlrtm1Her)
abnormal leukocyte migration J:82520
Ctsstm1Hap/Ctsstm1Hap
Tg(Scgb1a1-rtTA,tetO-Ifng)14Eli/0

(involves: 129S2/SvPas * C57BL/6 * CBA)
increased lymphocyte cell number J:100854
increased macrophage cell number J:100854
increased neutrophil cell number J:100854
Ctswtm1Ctnp/Ctswtm1Ctnp
(involves: 129X1/SvJ * C57BL/6)
immune system phenotype J:91265
Cttntm1.2Dvst/Cttntm1.2Dvst
(either: B6.Cg-Cttntm1.2Dvst or (involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2 * SJL))
abnormal cellular extravasation J:177602
abnormal leukocyte adhesion J:177602
abnormal leukocyte migration J:177602
abnormal neutrophil physiology J:177602
Cttnbp2tm1b(KOMP)Wtsi/Cttnbp2tm1b(KOMP)Wtsi
(C57BL/6N-Cttnbp2tm1b(KOMP)Wtsi/Wtsi)
decreased transitional stage T1 B cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased plasma cell number J:211773
Ctu2tm1(KOMP)Wtsi/Ctu2+
(C57BL/6N-Ctu2tm1(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Cuedc2tm1Qxia/Cuedc2tm1Qxia
(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac)
abnormal macrophage physiology J:211782
increased macrophage cytokine production J:211782
increased susceptibility to induced colitis J:211782
Cul4a/Pcid2tm2Ktc/Cul4a/Pcid2tm2Ktc
Tg(Mx1-cre)1Cgn/0

(involves: 129S/SvEv * C57BL/6 * CBA * FVB/N)
abnormal leukocyte morphology J:138468
abnormal spleen capsule morphology J:138468
abnormal spleen morphology J:138468
decreased lymphocyte cell number J:138468
decreased monocyte cell number J:138468
decreased neutrophil cell number J:138468
decreased spleen red pulp amount J:138468
decreased spleen weight J:138468
decreased spleen white pulp amount J:138468
small thymus J:138468
spleen hypoplasia J:138468
Cul4a/Pcid2tm2Ktc/Cul4a/Pcid2tm2Ktc
Tg(Mx1-cre)1Cgn/0

(involves: 129S/SvEv * C57BL/6 * CBA * FVB/N)
abnormal leukocyte morphology J:138468
abnormal spleen capsule morphology J:138468
abnormal spleen morphology J:138468
decreased lymphocyte cell number J:138468
decreased monocyte cell number J:138468
decreased neutrophil cell number J:138468
decreased spleen red pulp amount J:138468
decreased spleen weight J:138468
decreased spleen white pulp amount J:138468
small thymus J:138468
spleen hypoplasia J:138468
Cul4atm1b(EUCOMM)Hmgu/Cul4atm1b(EUCOMM)Hmgu
(C57BL/6N-Cul4atm1b(EUCOMM)Hmgu/Ccpcz)
decreased spleen weight J:211773
Cul5tm1.1(KOMP)Vlcg/Cul5+
(involves: C57BL/6NTac)
decreased interleukin-1 alpha secretion J:244502
decreased interleukin-6 secretion J:244502
decreased tumor necrosis factor secretion J:244502
Cul5tm1.1(KOMP)Vlcg/Cul5+
(C57BL/6N-Cul5tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Cul9em1(IMPC)Ccpcz/Cul9em1(IMPC)Ccpcz
(C57BL/6N-Cul9em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Cux1tm1Rhsc/Cux1tm1Rhsc
(involves: 129S1/Sv * C57BL/6J)
abnormal myelopoiesis J:100055
abnormal T cell differentiation J:100055
abnormal tumor necrosis factor level J:100055
decreased B cell number J:100055
decreased double-positive T cell number J:100055
decreased thymocyte number J:100055
small thymus J:100055
thymus cortex hypoplasia J:100055
thymus hypoplasia J:100055
Cux1tm2Ejn/Cux1tm2Ejn
(involves: 129S4/SvJae * C57BL/6)
increased susceptibility to bacterial infection J:74660
rhinitis J:74660
Cuzd1tm1Ljm/Cuzd1tm1Ljm
(involves: 129S6/SvEvTac * Black Swiss)
increased susceptibility to induced pancreatitis J:80980
Cwc22em1(IMPC)Mbp/Cwc22+
(C57BL/6NCrl-Cwc22em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
Cwc27tm1Lex/Cwc27tm1Lex
(B6;129S5-Cwc27tm1Lex/Mmucd)
abnormal immune system physiology J:171883
Cx3cl1tm1.1Yono/Cx3cl1tm1.1Yono
(involves: C57BL/6J)
abnormal dendritic cell physiology J:271242
decreased inflammatory response J:271242
Cx3cl1tm1Lira/Cx3cl1tm1Lira
(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:68831
Cx3cl1tm1Lira/Cx3cl1tm1Lira
(involves: C57BL/6)
decreased monocyte cell number J:145036
Cx3cl1tm1Sgs/Cx3cl1tm1Sgs
Ldlrtm1Her/Ldlrtm1Her

(involves: B6.129S4-Cx3cl1tm1Sgs * B6.129S7-Ldlrtm1Her/J)
impaired macrophage chemotaxis J:95279
Cx3cr1tm1Ifc/Cx3cr1tm1Ifc
(involves: 129S4/SvJae * C57BL/6)
abnormal NK cell physiology J:82033
abnormal response to transplant J:82033
immune system phenotype J:82033
impaired macrophage chemotaxis J:82033
Cx3cr1tm1Litt/Cx3cr1+
(B6.129P2-Cx3cr1tm1Litt)
increased susceptibility to experimental autoimmune encephalomyelitis J:129712
microgliosis J:110266
Cx3cr1tm1Litt/Cx3cr1+
Psen1tm1Mpm/Psen1tm1Mpm
Tg(APPSwe,tauP301L)1Lfa/0
Tg(Thy1-YFP)HJrs/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal microglial cell morphology J:159680
abnormal microglial cell physiology J:159680
Cx3cr1tm1Litt/Cx3cr1tm1Litt
(involves: 129P2/OlaHsd * C57BL/6)
abnormal leukocyte physiology J:162714
decreased monocyte cell number J:145036
immune system phenotype J:84544
impaired macrophage chemotaxis J:162714
Cx3cr1tm1Litt/Cx3cr1tm1Litt
(C.129P2-Cx3cr1tm1Litt)
immune system phenotype J:84544
Cx3cr1tm1Litt/Cx3cr1tm1Litt
(involves: 129P2/OlaHsd)
abnormal dendritic cell physiology J:271242, J:95694
decreased inflammatory response J:271242
increased dendritic cell number J:210086
increased susceptibility to bacterial infection induced morbidity/mortality J:95694
Cx3cr1tm1Litt/Cx3cr1tm1Litt
(B6.129P2-Cx3cr1tm1Litt)
abnormal leukocyte physiology J:124722
abnormal microglial cell morphology J:265696
abnormal microglial cell physiology J:110266, J:265696
abnormal NK cell physiology J:129712
brain inflammation J:129712
decreased NK cell number J:129712
immune system phenotype J:129712
increased susceptibility to experimental autoimmune encephalomyelitis J:129712
microgliosis J:110266
Cx3cr1tm1Litt/Cx3cr1tm1Litt
H2-Ab1b-tm1Hpl/H2-Ab1+

(involves: 129P2/OlaHsd * 129S4/SvJae)
abnormal response to infection J:95694
Cx3cr1tm1Zm/Cx3cr1tm1Zm
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal splenocyte physiology J:103047
Cx3cr1tm2.1(cre/ERT2)Litt/Cx3cr1+
Vps35Gt(RRK261)Byg/Vps35Gt(RRK261)Byg

(involves: 129P2/OlaHsd * C57BL/6)
decreased interleukin-1 beta secretion J:292365
decreased interleukin-6 secretion J:292365
decreased tumor necrosis factor secretion J:292365
increased interleukin-4 secretion J:292365
increased interleukin-10 secretion J:292365
increased macrophage cell number J:292365
microgliosis J:292365
Cx3cr1tm3(Hbegf)Litt/Cx3cr1tm3(Hbegf)Litt
Tg(Itgax-cre)1-1Reiz/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased susceptibility to bacterial infection J:210086
Cxadrem1(IMPC)Mbp/Cxadr+
(C57BL/6N-Cxadrem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Cxadrtm1.1Ics/Cxadrtm1.1Ics
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA)
enlarged thymus J:174138
increased thymocyte number J:174138
Cxcl1em1(IMPC)Mbp/Cxcl1em1(IMPC)Mbp
(C57BL/6N-Cxcl1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
Cxcl5tm1.1Mkch/Cxcl5tm1.1Mkch
(B6.129P2-Cxcl5tm1.1Mkch)
decreased interferon-alpha secretion J:208901
decreased interleukin-1 alpha secretion J:208901
decreased interleukin-6 secretion J:208901
decreased neutrophil cell number J:208901
decreased susceptibility to bacterial infection J:208901
decreased susceptibility to bacterial infection induced morbidity/mortality J:208901
decreased tumor necrosis factor secretion J:208901
immune system phenotype J:208901
Cxcl5tm1Gscw/Cxcl5tm1Gscw
(involves: 129)
abnormal circulating chemokine level J:162629
abnormal neutrophil physiology J:162629
decreased circulating interleukin-6 level J:162629
decreased susceptibility to bacterial infection J:162629
decreased susceptibility to bacterial infection induced morbidity/mortality J:162629
decreased susceptibility to endotoxin shock J:162629
increased granulocyte number J:162629
Cxcl5tm1Gscw/Cxcl5tm1Gscw
Ackr1tm1Scp/Ackr1tm1Scp

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal circulating chemokine level J:162629
Cxcl9tm1b(EUCOMM)Wtsi/Cxcl9tm1b(EUCOMM)Wtsi
(C57BL/6N-Cxcl9tm1b(EUCOMM)Wtsi/H)
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Cxcl9tm1Jmf/Cxcl9tm1Jmf
(either: B6.129S4-Cxcl9tm1Jmf or (involves: 129S4/SvJae * C57BL/6))
decreased IgG level J:121818
decreased immunoglobulin level J:121818
immune system phenotype J:121818
Cxcl9tm1Jmf/Cxcl9tm1Jmf
(B6.129S4-Cxcl9tm1Jmf)
abnormal cytokine secretion J:120743
decreased inflammatory response J:120743
Cxcl10tm1Adl/Cxcl10tm1Adl
(involves: 129S4/SvJae * 129X1/SvJ)
decreased IgG2a level J:75584
decreased interferon-gamma secretion J:75584
decreased splenocyte proliferation J:75584
decreased susceptibility to type IV hypersensitivity reaction J:75584
Cxcl10tm1Adl/Cxcl10tm1Adl
(involves: 129S4/SvJae * C57BL/6)
abnormal interferon level J:75584
abnormal T cell physiology J:75584
decreased CD8-positive, alpha-beta T cell number J:75584
increased susceptibility to Hepadnaviridae infection J:75584
Cxcl10tm1Adl/Cxcl10tm1Adl
(B6.129S4-Cxcl10tm1Adl)
abnormal cytokine secretion J:120743
CNS inflammation J:87076
increased susceptibility to experimental autoimmune encephalomyelitis J:87076
increased susceptibility to Herpesvirales infection J:120743
Cxcl11em1Groj/Cxcl11em1Groj
(C57BL/6J-Cxcl11em1Groj)
abnormal B cell morphology J:345391
immune system phenotype J:345391
increased CD8-positive, alpha-beta T cell number J:345391
Cxcl12tm1.1Sjm/Cxcl12tm1.1Sjm
Ndor1Tg(UBC-cre/ERT2)1Ejb/?

(involves: 129S/SvEv * C57BL/6)
decreased leukocyte cell number J:194748
decreased lymphocyte cell number J:194748
Cxcl12tm1.1Sjm/Cxcl12tm1.1Sjm
Tg(Prrx1-cre)1Cjt/?

(involves: C57BL/6 * SJL/J)
abnormal B cell differentiation J:194748
Cxcl12tm1.1Ystz/Cxcl12tm1.2Ystz
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129X1/SvJ * C57BL/6 * CBA * FVB/N)
decreased pro-B cell number J:168434
increased neutrophil cell number J:168434
Cxcl12tm1Tng/Cxcl12tm1.1Link
Tg(BGLAP-cre)1Clem/0

(involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NTac * FVB/N)
decreased B cell number J:193594
Cxcl12tm1Tng/Cxcl12tm1.1Link
Tg(Prrx1-cre)1Cjt/0

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL/J)
decreased B cell number J:193594
decreased pre-pro B cell number J:193594
Cxcl12tm1Tng/Cxcl12tm1.1Link
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

(involves: 129P2/OlaHsd * C57BL/6 * CD-1 * FVB/N)
decreased B cell number J:193594
decreased pre-pro B cell number J:193594
Cxcl12tm1Tng/Cxcl12tm1Tng
(involves: 129P2/OlaHsd)
decreased pre-B cell number J:34750
decreased pro-B cell number J:34750
impaired myelopoiesis J:49070
Cxcl12tm3.1(HBEGF/EGFP)Tng/Cxcl12+
(B6.Cg-Cxcl12tm3.1(HBEGF/EGFP)Tng)
decreased pro-B cell number J:164657
increased B cell apoptosis J:164657
Cxcl13em2(IMPC)H/Cxcl13em2(IMPC)H
(C57BL/6NTac-Cxcl13em2(IMPC)H/H)
increased basophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Cxcl13m1Btlr/Cxcl13m1Btlr
(C57BL/6J-Cxcl13m1Btlr)
increased B-1 B cell number J:221480
Cxcl13tm1Cys/Cxcl13tm1Cys
(involves: 129X1/SvJ * C57BL/6)
abnormal B cell physiology J:78282
abnormal lymph node germinal center morphology J:78282
abnormal Peyer's patch morphology J:78282
abnormal spleen B cell follicle morphology J:78282
abnormal spleen marginal zone morphology J:78282
absent axillary lymph nodes J:78282
absent brachial lymph nodes J:78282
absent follicular dendritic cells J:78282
absent inguinal lymph nodes J:78282
decreased lymph node number J:78282
decreased Peyer's patch number J:78282
decreased spleen germinal center size J:78282
small Peyer's patches J:78282
Cxcl13tm1Cys/Cxcl13tm1Cys
(B6.129X1-Cxcl13tm1Cys)
abnormal B cell physiology J:118931
Cxcl13tm1Mmi/Cxcl13tm1Mmi
(involves: C57BL/6)
abnormal B cell physiology J:84804
abnormal leukocyte adhesion J:84804
abnormal leukocyte migration J:84804
Cxcl14tm1Bmsr/Cxcl14tm1Bmsr
(involves: 129/Sv * C57BL/6)
immune system phenotype J:118303
Cxcl14tm1Tha/Cxcl14tm1Tha
(involves: C57BL/6 * CBA)
decreased macrophage cell number J:126841
Cxcl15tm1Lira/Cxcl15tm1Lira
(involves: 129 * C57BL/6J)
decreased neutrophil cell number J:67605
immune system phenotype J:67605
increased susceptibility to bacterial infection J:67605
Cxcl16tm1Syon/Cxcl16tm1Syon
(B6.129P2-Cxcl16tm1Syon)
decreased circulating interferon-gamma level J:155199
decreased circulating interleukin-4 level J:155199
decreased interferon-gamma secretion J:155199
decreased interleukin-4 secretion J:155199
decreased NK T cell number J:155199
decreased susceptibility to bacterial infection J:155199
Cxcr2tm1(IL8RB)Dktr/Cxcr2tm1(IL8RB)Dktr
(involves: 129S2/SvPas * C57BL/6)
decreased spleen weight J:113489
immune system phenotype J:113489
increased granulocyte number J:113489
increased leukocyte cell number J:113489
Cxcr2tm1a(EUCOMM)Wtsi/Cxcr2tm1a(EUCOMM)Wtsi
(C57BL/6N-Cxcr2tm1a(EUCOMM)Wtsi/Wtsi)
decreased B cell number J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased immature B cell number J:211773
decreased mature B cell number J:211773
decreased pre-B cell number J:211773
decreased pre-pro B cell number J:211773
decreased T cell number J:211773
increased anti-nuclear antigen antibody level J:211773
increased CD4-positive, alpha-beta memory T cell number J:211773
increased CD8-positive, alpha-beta memory T cell number J:211773
increased CD103-positive CD11b-low dendritic cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased eosinophil cell number J:211773
increased gamma-delta T cell number J:211773
increased granulocyte number J:211773
increased KLRG1+ CD4 alpha-beta T cell number J:211773
increased KLRG1+ CD8 alpha-beta T cell number J:211773
increased leukocyte cell number J:211773
increased Ly6C high monocyte number J:211773
increased Ly6C low monocyte number J:211773
increased memory-marker CD4-positive NK T cell number J:211773
increased memory-marker gamma-delta T cell number J:211773
increased memory-marker NK cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Cxcr2tm1Mwm/Cxcr2+
(C.129S2(B6)-Cxcr2tm1Mwm/J)
impaired neutrophil recruitment J:63935
Cxcr2tm1Mwm/Cxcr2tm1Mwm
(involves: 129S2/SvPas * C57BL/6J)
abnormal granulocyte differentiation J:19570
abnormal myelopoiesis J:19570
abnormal spleen white pulp morphology J:19570
enlarged cervical lymph nodes J:19570
enlarged lymph nodes J:19570
enlarged spleen J:19570
impaired neutrophil chemotaxis J:19570
increased B cell number J:19570
increased circulating interleukin-6 level J:19570
increased neutrophil cell number J:19570
lymph node medullary cord hyperplasia J:19570
myeloid hyperplasia J:19570
Cxcr2tm1Mwm/Cxcr2tm1Mwm
(C.129S2(B6)-Cxcr2tm1Mwm/J)
abnormal chemokine level J:73947
abnormal cytokine secretion J:72824
abnormal eosinophil physiology J:73947
abnormal interleukin level J:73947, J:87365
abnormal leukocyte physiology J:94170
abnormal neutrophil physiology J:93946, J:73947
abnormal NK T cell physiology J:66399
abnormal T cell physiology J:73947
abnormal T-helper 1 physiology J:73947
abnormal T-helper 2 physiology J:73947
decreased susceptibility to fungal infection J:73947
decreased susceptibility to induced arthritis J:142880
impaired neutrophil chemotaxis J:65905, J:72824
impaired neutrophil recruitment J:65425, J:63935, J:93116
increased IgE level J:73947
increased susceptibility to bacterial infection J:65905
increased susceptibility to Herpesvirales infection J:87365
increased susceptibility to parasitic infection J:72824
Cxcr2tm1Mwm/Cxcr2tm1Mwm
(involves: 129S2/SvPas * BALB/c)
abnormal myelopoiesis J:113489
abnormal neutrophil physiology J:113489
decreased thymus weight J:113489
increased granulocyte number J:113489
increased spleen weight J:113489
Cxcr2tm1Mwm/Cxcr2tm1Mwm
(involves: 129S2/SvPas)
decreased susceptibility to bacterial infection induced morbidity/mortality J:208901
Cxcr2tm1Rmra/Cxcr2tm1Rmra
Tg(Mx1-cre)1Cgn/0

(involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * CBA)
abnormal neutrophil physiology J:204482
Cxcr3tm1Raks/Cxcr3tm1Raks
(B6.129P2-Cxcr3tm1Raks)
kidney inflammation J:152790
Cxcr3tm1Wwh/Y
(B6.Cg-Cxcr3tm1Wwh)
abnormal cellular extravasation J:107646
abnormal interferon level J:91359
impaired macrophage chemotaxis J:107646
increased length of allograft survival J:65916
lung inflammation J:91359
Cxcr3tm1Wwh/Cxcr3tm1Wwh
(B6.Cg-Cxcr3tm1Wwh)
abnormal cellular extravasation J:96905, J:107646
abnormal interferon level J:91359
decreased susceptibility to Riboviria infection J:96905
decreased susceptibility to Riboviria infection induced morbidity/mortality J:96905
impaired macrophage chemotaxis J:107646
increased length of allograft survival J:65916
lung inflammation J:91359
Cxcr4em1(IMPC)Mbp/Cxcr4+
(C57BL/6NCrl-Cxcr4em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Cxcr4tm1.1Bala/Cxcr4+
(B6.129S2-Cxcr4tm1.1Bala)
abnormal CD4-positive, alpha-beta T cell number J:186735
abnormal immune system cell morphology J:186735
abnormal immune system morphology J:186735
abnormal immune system organ morphology J:186735
abnormal immune system physiology J:186735
abnormal lymph node B cell domain morphology J:186735
abnormal lymph node morphology J:186735
abnormal neutrophil morphology J:186735
abnormal NK cell physiology J:178789
abnormal spleen morphology J:186735
abnormal spleen white pulp morphology J:186735
abnormal thymus morphology J:186735
decreased B cell apoptosis J:186735
decreased B cell number J:186735
decreased immature B cell number J:186735
decreased leukocyte cell number J:186735
decreased NK cell number J:178789
decreased spleen weight J:186735
decreased T cell number J:186735
increased IgG level J:186735
increased IgM level J:186735
increased immunoglobulin level J:186735
increased mature B cell number J:186735
increased NK cell number J:178789
Cxcr4tm1Qma/Cxcr4tm1Qma
(involves: 129X1/SvJ)
decreased pro-B cell number J:49070
impaired myelopoiesis J:49070
Cxcr4tm1Qma/Cxcr4tm1Qma
(involves: 129X1/SvJ * C57BL/6)
decreased susceptibility to Retroviridae infection J:132342
increased susceptibility to Retroviridae infection induced morbidity/mortality J:132342
Cxcr4tm1Tng/Cxcr4tm1Tng
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:69256
failure of myelopoiesis J:69256
Cxcr4tm1Tng/Cxcr4tm1Tng
(B6.Cg-Cxcr4tm1Tng)
abnormal T cell differentiation J:82996
decreased double-positive T cell number J:82996
Cxcr4tm1Yiw/Cxcr4tm1Yiw
Tg(Lck-cre)1Jtak/0

(involves: 129P2/OlaHsd)
abnormal leukocyte migration J:164872
decreased susceptibility to induced arthritis J:164872
decreased thymocyte number J:164872
Cxcr4tm1Yzo/Cxcr4tm1Yzo
(Not Specified)
abnormal B cell differentiation J:167314
abnormal B cell physiology J:167314
abnormal leukopoiesis J:69255
abnormal lymphopoiesis J:69255
impaired myelopoiesis J:69255
Cxcr4tm2Yzo/Cxcr4tm2Yzo
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:94911
abnormal Peyer's patch follicle morphology J:94911
decreased B-1 B cell number J:94911
decreased B-2 B cell number J:94911
decreased immunoglobulin level J:94911
decreased mature B cell number J:94911
decreased plasma cell number J:94911
Cxcr4tm2Yzo/Cxcr4tm2Yzo
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
increased lymphocyte cell number J:217569
increased monocyte cell number J:217569
increased neutrophil cell number J:217569
Cxcr4tm2Yzo/Cxcr4tm2Yzo
Tg(Fabp4-cre)1Rev/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage cell number J:217569
decreased B cell number J:217569
decreased CD4-positive, alpha-beta T cell number J:217569
increased CD8-positive, alpha-beta T cell number J:217569
Cxcr4tm2Yzo/Cxcr4tm3.1Yzo
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:167314
Cxcr4tm3.1Yzo/Cxcr4tm3.1Yzo
(Not Specified)
abnormal B cell physiology J:167314
decreased pro-B cell number J:167314
impaired myelopoiesis J:167314
Cxcr5tm1.1Namt/Cxcr5tm1.1Namt
Tg(Itgax-cre)1-1Reiz/0

(involves: C57BL/6 * C57BL/6J * CBA)
abnormal dendritic cell chemotaxis J:241561
decreased follicular dendritic cell number J:241561
decreased susceptibility to prion infection J:241561
immune system phenotype J:241561
Cxcr5tm1.1Namt/Cxcr5tm1.1Namt
Tg(Itgax-cre)1-1Reiz/0
Tg(Prnp)a20Cwe/0

(involves: C57BL/6 * C57BL/6J * CBA)
decreased susceptibility to prion infection J:241561
Cxcr5tm1Lipp/Cxcr5tm1Lipp
(involves: 129S2/SvPas * CD-1)
abnormal leukocyte migration J:37126
abnormal Peyer's patch morphology J:37126
abnormal spleen primary B follicle morphology J:37126
abnormal spleen secondary B follicle morphology J:37126
absent axillary lymph nodes J:78282
absent brachial lymph nodes J:78282
absent cervical lymph nodes J:78282
absent follicular dendritic cells J:78282
absent inguinal lymph nodes J:78282, J:37126
absent lymph nodes J:78282
absent Peyer's patches J:37126
absent spleen germinal center J:37126
increased B cell number J:37126
Cxv1F/St/Cxv1F/St
(involves: AKR/J * F/St)
abnormal immune cell physiology J:7030
Cxv2DBA/2J/?
(involves: C57BL/6J * DBA/2J)
abnormal immune cell physiology J:6143
Cyb5d1tm1.1(KOMP)Vlcg/Cyb5d1tm1.1(KOMP)Vlcg
(B6N(Cg)-Cyb5d1tm1.1(KOMP)Vlcg/J)
increased leukocyte cell number J:211773
Cyb5r3tm1c(KOMP)Wtsi/Cyb5r3tm1c(KOMP)Wtsi
Tg(Myh11-icre/ERT2)1Soff/0

(B6.Cg-Cyb5r3tm1c(KOMP)Wtsi Tg(Myh11-icre/ERT2)1Soff)
decreased monocyte cell number J:280543
Cyb561d2tm1b(EUCOMM)Wtsi/Cyb561d2tm1b(EUCOMM)Wtsi
(C57BL/6N-Cyb561d2tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Cybanmf333/Cybanmf333
(A.B6 Tyr+-Cybanmf333/J)
abnormal neutrophil physiology J:132359
increased inflammatory response J:132359
increased susceptibility to bacterial infection J:132359
lung inflammation J:132359
sepsis J:132359
Cybatm1a(EUCOMM)Wtsi/Cybatm1a(EUCOMM)Wtsi
(C57BL/6N-Cybatm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Cybatm1Dgh/Cybatm1Dgh
(B6.Cg-Cybatm1Dgh)
abnormal T cell activation J:231269
decreased inflammatory response J:231269
Cybbtm1.1Abk/Cybbtm1.1Abk
Lyz2tm1(cre)Ifo/?

(B6.Cg-Lyz2tm1(cre)Ifo Cybbtm1.1Abk)
abnormal macrophage chemotaxis J:245699
enlarged spleen J:245699
Cybbtm1Din/Y
(involves: 129S/SvEv * C57BL/6)
abnormal immune system physiology J:22868
abnormal macrophage physiology J:22868
abnormal neutrophil physiology J:22868
increased inflammatory response J:22868
increased susceptibility to bacterial infection J:22868
increased susceptibility to infection J:22868
Cybbtm1Din/Cybbtm1Din
(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:64232
Cybbtm1Din/Cybbtm1Din
(B6.129S-Cybbtm1Din)
granulomatous inflammation J:146231
immune system phenotype J:113463
increased acute inflammation J:110181
Cybbtm1Din/Cybbtm1Din
(B6.129S-Cybbtm1Din/J)
abnormal circulating chemokine level J:235399
abnormal macrophage physiology J:235399
decreased circulating interleukin-10 level J:235399
glomerulonephritis J:235399
increased anti-double stranded DNA antibody level J:235399
increased anti-nuclear antigen antibody level J:235399
increased autoantibody level J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
increased circulating interleukin-12b level J:235399
increased IgG level J:235399
increased lymphocyte cell number J:235399
increased monocyte cell number J:235399
increased neutrophil cell number J:235399
increased susceptibility to systemic lupus erythematosus J:235399
Cybbtm1Din/Cybbtm1Din
Nrrostm1Lex/Nrrostm1Lex

(B6.129S-Nrrostm1Lex Cybbtm1Din)
immune system phenotype J:209569
Cybbtm2b(KOMP)Wtsi/Cybbtm2b(KOMP)Wtsi
(C57BL/6N-Cybbtm2b(KOMP)Wtsi/H)
increased spleen weight J:211773
Cycstm1Mak/Cycstm1Mak
(involves: C57BL/6)
absent pre-B cells J:98949
decreased B cell number J:98949
decreased leukocyte cell number J:98949
decreased T cell number J:98949
increased spleen weight J:98949
spleen hyperplasia J:98949
thymus atrophy J:98949
thymus hypoplasia J:98949
Cyldtm1.1Awai/Cyldtm1.1Awai
(Not Specified)
abnormal B cell differentiation J:126113
abnormal B cell morphology J:126113
abnormal B cell physiology J:126113
abnormal class switch recombination J:126113
abnormal humoral immune response J:126113
abnormal Peyer's patch germinal center morphology J:126113
abnormal spleen marginal zone morphology J:126113
abnormal spleen morphology J:126113
decreased B-1 B cell number J:126113
decreased IgG3 level J:126113
decreased IgM level J:126113
decreased immature B cell number J:126113
enlarged lymph nodes J:126113
enlarged Peyer's patches J:126113
enlarged spleen J:126113
increased B cell number J:126113
increased follicular B cell number J:126113
increased IgA level J:126113
increased IgG1 level J:126113
increased IgG2a level J:126113
increased IgG2b level J:126113
increased marginal zone B cell number J:126113
increased pro-B cell number J:126113
Cyldtm1.1Mpa/Cyldtm1.1Mpa
Faddtm1Mpa/Faddtm1Mpa
Tg(Vil1-cre)997Gum/0

(B6.Cg-Faddtm1Mpa Cyldtm1.1Mpa Tg(Vil1-cre)997Gum)
cecum inflammation J:175865
Cyldtm1.1Mpa/Cyldtm1.1Mpa
Ikbkgtm1.1Mpa/Y
Tg(Vil1-cre)997Gum/0

(B6.Cg-Cyldtm1.1Mpa Ikbkgtm1.1Mpa Tg(Vil1-cre)997Gum)
colitis J:175865
Cyldtm1.1Mpa/Cyldtm1.1Mpa
Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa
Tg(Vil1-cre)997Gum/0

(B6.Cg-Cyldtm1.1Mpa Ikbkgtm1.1Mpa Tg(Vil1-cre)997Gum)
colitis J:175865
Cyldtm1Awai/Cyldtm1Awai
Tg(CD19-cre/ERT2)1Cgn/?

(Not Specified)
abnormal mature B cell morphology J:126113
decreased B-1 B cell number J:126113
decreased immature B cell number J:126113
enlarged lymph nodes J:126113
enlarged Peyer's patches J:126113
enlarged spleen J:126113
increased B cell number J:126113
Cyldtm1Jdgl/Cyldtm1Jdgl
(involves: 129 * C57BL/6J)
decreased susceptibility to bacterial infection J:124327
decreased susceptibility to bacterial infection induced morbidity/mortality J:124327
Cyldtm1Lex/Cyldtm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal inflammatory response J:114972
immune system phenotype J:114972
increased susceptibility to induced colitis J:114972
thymus hyperplasia J:114972
Cyldtm1Ref/Cyldtm1Ref
(Not Specified)
immune system phenotype J:126113
Cyldtm1Scs/Cyldtm1Scs
(involves: 129S1/Sv * 129X1/SvJ)
abnormal B cell differentiation J:112392
abnormal T cell number J:112392
decreased CD4-positive, alpha-beta T cell number J:112392
decreased CD8-positive, alpha-beta T cell number J:112392
increased double-positive T cell number J:112392
Cyp1a1tm1.1Dwn/Cyp1a1tm1.1Dwn
(B6.129P2-Cyp1a1tm1.1Dwn)
decreased lymphocyte cell number J:163973
decreased spleen weight J:163973
decreased thymus weight J:163973
increased neutrophil cell number J:163973
Cyp1a1tm1.1Dwn/Cyp1a1tm1.1Dwn
(involves: 129P2/OlaHsd * C57BL/6)
decreased leukocyte cell number J:122409
small spleen J:122409
small thymus J:122409
Cyp1a1tm4.1Dwn/Cyp1a1tm4.1Dwn
(B6.129X1-Cyp1a1tm4.1Dwn)
decreased lymphocyte cell number J:163973
decreased spleen weight J:163973
decreased thymus weight J:163973
increased neutrophil cell number J:163973
Cyp1atm1Dwn/Cyp1atm1Dwn
(B6.129-Cyp1atm1Dwn)
decreased leukocyte cell number J:122409
small spleen J:122409
small thymus J:122409
Cyp2ab1tm1b(KOMP)Wtsi/Cyp2ab1tm1b(KOMP)Wtsi
(C57BL/6N-Cyp2ab1tm1b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Cyp2ctm1104Arte/Cyp2ctm1104Arte
(B6NTac(Cg)-Cyp2ctm1104Arte/Arte)
liver inflammation J:241121
Cyp2ctm1897.1(Alb-CYP2C9)Arte/Cyp2ctm1897.1(Alb-CYP2C9)Arte
(B6(Cg)-Cyp2ctm1897.1(Alb-CYP2C9)Arte/Arte)
liver inflammation J:241121
Cyp2d22em1(IMPC)Tcp/Cyp2d22em1(IMPC)Tcp
(C57BL/6NCrl-Cyp2d22em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Cyp2f2em1(IMPC)H/Cyp2f2em1(IMPC)H
(C57BL/6N-Cyp2f2em1(IMPC)H/H)
enlarged spleen J:211773
Cyp2g1tm1(rtTA)Lane/Cyp2g1+
Tg(SFTPC-rtTA,tetO-Tnf)320-1Gwho/0

(involves: 129 * C57BL/6 * SJL)
increased macrophage cell number J:157842
rhinitis J:157842
Cyp4v3em1Xsu/Cyp4v3em1Xsu
(C57BL/6J-Cyp4v3em1Xsu)
increased microglial cell activation J:321817
Cyp7a1tm1b(EUCOMM)Wtsi/Cyp7a1tm1b(EUCOMM)Wtsi
(C57BL/6N-Cyp7a1tm1b(EUCOMM)Wtsi/Ieg)
increased leukocyte cell number J:211773
Cyp7b1tm1Rus/Cyp7b1tm1Rus
(involves: 129S/SvEv * C57BL/6J)
decreased IgA level J:170807
Cyp11a1tm2Bcc/Cyp11a1tm2Bcc
(Not Specified)
decreased T cell apoptosis J:133007
Cyp11b1tm1Chjk/Cyp11b1tm1Chjk
(involves: 129P2/OlaHsd * C57BL/6J)
decreased thymus weight J:147610
Cyp19a1tm1b(EUCOMM)Hmgu/Cyp19a1tm1b(EUCOMM)Hmgu
(C57BL/6N-Cyp19a1tm1b(EUCOMM)Hmgu/H)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Cyp19a1tm1Esi/Cyp19a1tm1Esi
(involves: 129S6/SvEvTac * C57BL/6)
abnormal spleen germinal center morphology J:92438
enlarged mesenteric lymph nodes J:92438
enlarged spleen J:92438
increased autoantibody level J:92438
increased B cell number J:92438
increased granulocyte number J:92438
increased IgG level J:92438
increased leukocyte cell number J:92438
increased lymphocyte cell number J:92438
increased mature B cell number J:92438
kidney inflammation J:92438
salivary gland inflammation J:92438
spleen hyperplasia J:92438
Cyp19a1tm1Sih/Cyp19a1tm1Sih
(involves: 129S/SvEv)
increased anti-single stranded DNA antibody level J:216958
increased autoantibody level J:216958
increased dendritic cell number J:216958
increased macrophage cell number J:216958
increased susceptibility to autoimmune disorder J:216958
lacrimal gland inflammation J:216958
salivary gland inflammation J:216958
Cyp19a1tm1Toda/Cyp19a1tm1Toda
(involves: 129P2/OlaHsd * C57BL/6J)
increased osteoclast cell number J:114305
Cyp21a1em1(IMPC)Tcp/Cyp21a1+
(C57BL/6NCrl-Cyp21a1em1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
Cyp26b1tm1Hmd/Cyp26b1tm1Hmd
(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymphatic vessel endothelial cell morphology J:206581
Cyp26b1tm1Hmd/Cyp26b1tm1Hmd
Tg(Prox1-EGFP)KY221Gsat/0

(involves: 129S1/Sv * 129X1/SvJ * FVB/NTac)
abnormal lymphatic vessel endothelial cell morphology J:206581
abnormal lymphatic vessel morphology J:206581
Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu
(C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
Cyp27b1tm1Dgo/Cyp27b1tm1Dgo
(involves: 129S1/Sv * 129X1/SvJ * BALB/c)
decreased osteoclast cell number J:70030
decreased T cell number J:70030
enlarged lymph nodes J:70030
Cyp51tm1.1Bfro/Cyp51tm1.1Bfro
(involves: 129P2/OlaHsd * C57BL/6)
abnormal lymphatic vessel morphology J:173366
abnormal lymphatic vessel smooth muscle morphology J:173366
Cypr1STS/A/?
(involves: BALB/c * STS/A)
abnormal cytokine secretion J:52119
Cypr2BALB/c/?
(involves: BALB/c * STS/A)
abnormal cytokine secretion J:52119
Cypr3BALB/c/?
(involves: BALB/c * STS/A)
abnormal cytokine secretion J:52119
Cyrenem1Vokh/Cyrenem1Vokh
(C57BL/6-Cyrenem1Vokh)
abnormal class switch recombination J:306598
Cyrentm1.1(KOMP)Vlcg/Cyrentm1.1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal class switch recombination J:265834
Cyribm1Ivdi/Cyribm1Ivdi
(involves: 129S1/Sv * 129X1/SvJ * DBA/2J)
abnormal spleen morphology J:282597
abnormal spleen white pulp morphology J:282597
increased circulating interleukin-6 level J:282597
increased circulating interleukin-10 level J:282597
increased circulating tumor necrosis factor level J:282597
increased neutrophil cell number J:282597
increased susceptibility to bacterial infection induced morbidity/mortality J:282597
Cyribtm1c(KOMP)Wtsi/Cyribtm1d(KOMP)Wtsi
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * BcA17/Skmn * C57BL/6N)
abnormal circulating chemokine level J:282597
abnormal neutrophil physiology J:282597
increased circulating CXCL10 level J:282597
increased circulating interleukin-6 level J:282597
increased circulating interleukin-10 level J:282597
increased circulating tumor necrosis factor level J:282597
increased susceptibility to bacterial infection induced morbidity/mortality J:282597
Cys1cpk/Cys1cpk
(involves: C57BL/6J * CD-1)
spleen hypoplasia J:33739
thymus hypoplasia J:33739
Cys1cpk/Cys1cpk
(129.B6-Cys1cpk)
liver inflammation J:116210
Cysltr1tm1Ykn/Cysltr1tm1Ykn
(involves: C57BL/6)
decreased susceptibility to type I hypersensitivity reaction J:77087
respiratory system inflammation J:88647
Cysltr1tm1Ykn/Cysltr1tm1Ykn
(C.B6-Cysltr1tm1Ykn)
immune system phenotype J:182213
Cysltr1tm1Ykn/Cysltr1tm1Ykn
Cysltr2tm1Ykn/Cysltr2tm1Ykn

(involves: BALB/c * C57BL/6)
abnormal immune system physiology J:198383
Cysltr1tm1Ykn/Cysltr1tm1Ykn
Cysltr2tm1Ykn/Cysltr2tm1Ykn
Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg

(involves: BALB/c * C57BL/6 * C57BL/6NTac)
abnormal immune system physiology J:198383
Cysltr2tm1Ykn/Cysltr2tm1Ykn
(C57BL/6-Cysltr2tm1Ykn)
decreased susceptibility to type I hypersensitivity reaction J:94488
Cysltr2tm1Ykn/Cysltr2tm1Ykn
(C.B6-Cysltr2tm1Ykn)
autoimmune response J:182213
Cystm1tm1b(EUCOMM)Hmgu/Cystm1tm1b(EUCOMM)Hmgu
(C57BL/6N-Cystm1tm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Cyth2tm1d(EUCOMM)Wtsi/Cyth2tm1d(EUCOMM)Wtsi
(involves: C57BL/6N)
decreased eosinophil cell number J:307633
decreased susceptibility to type I hypersensitivity reaction J:307633
Cytiptm1Tes/Cytiptm1Tes
(involves: 129S1/Sv * FVB/N)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:110320
abnormal cellular extravasation J:110320
abnormal leukocyte migration J:110320
decreased leukocyte cell number J:110320
decreased lymphocyte cell number J:110320
lymph node hypoplasia J:110320
Cytiptm1Wtw/Cytiptm1Wtw
(involves: 129S6/SvEvTac * C57BL/6)
abnormal response to transplant J:112168
immune system phenotype J:112168
Cytl1tm1Chun/Cytl1tm1Chun
(involves: 129S4/SvJae * C57BL/6)
increased susceptibility to induced arthritis J:175377
D6Wsu163etm1b(EUCOMM)Wtsi/D6Wsu163etm1b(EUCOMM)Wtsi
(C57BL/6N-D6Wsu163etm1b(EUCOMM)Wtsi/Wtsi)
decreased CD4-positive, alpha-beta T cell number J:211773
decreased memory-marker NK cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
D630045J12Riktm1b(KOMP)Wtsi/D630045J12Riktm1b(KOMP)Wtsi
(C57BL/6N-D630045J12Riktm1b(KOMP)Wtsi/Tcp)
enlarged lymph nodes J:211773
Daam2tm1b(KOMP)Wtsi/Daam2tm1b(KOMP)Wtsi
(C57BL/6N-Daam2tm1b(KOMP)Wtsi/Wtsi)
increased large unstained cell number J:211773
Dab1scm-4J/Dab1scm-4J
(CBA/J-Dab1scm-4J/GrsrJ)
thymus atrophy J:153275
Dach2em1(IMPC)Ccpcz/Dach2em1(IMPC)Ccpcz
(C57BL/6NCrl-Dach2em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased eosinophil cell number J:211773
small lymph nodes J:211773
small spleen J:211773
Dact2tm1b(EUCOMM)Wtsi/Dact2tm1b(EUCOMM)Wtsi
(C57BL/6N-Dact2tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Dad1tm1Kni/Dad1+
(involves: 129S/SvEv)
decreased thymus weight J:99897
Daglatm1a(EUCOMM)Wtsi/Daglatm1a(EUCOMM)Wtsi
(C57BL/6N-Daglatm1a(EUCOMM)Wtsi/Nju)
small spleen J:211773
small thymus J:211773
Dapp1Gt(OST111213)Lex/Dapp1Gt(OST111213)Lex
(B6.Cg-Dapp1Gt(OST111213)Lex)
abnormal humoral immune response J:110009
decreased B cell proliferation J:110009
decreased IgG3 level J:110009
increased susceptibility to bacterial infection J:110009
Dapp1tm1Mnz/Dapp1tm1Mnz
(B6.129P2-Dapp1tm1Mnz)
abnormal B cell activation J:86182
decreased B cell proliferation J:86182
decreased B-1a cell number J:86182
decreased IgG3 level J:86182
decreased IgM level J:86182
Daw1b2b1116Clo/Daw1b2b1116Clo
(C57BL/6J-Daw1b2b1116Clo)
spleen hypoplasia J:175213
Daw1b2b1584Clo/Daw1b2b1584Clo
(C57BL/6J-Daw1b2b1584Clo)
absent spleen J:175213
Dazap1em1(IMPC)Ccpcz/Dazap1+
(C57BL/6NCrl-Dazap1em1(IMPC)Ccpcz/Ccpcz)
increased eosinophil cell number J:211773
DbaclC57BL/6Jcl/DbaclC57BL/6Jcl
(NOD.B6-(D4Mit193-D4Mit17))
increased susceptibility to autoimmune diabetes J:144964
insulitis J:144964
Dbn1tm1a(KOMP)Wtsi/Dbn1+
(C57BL/6N-Dbn1tm1a(KOMP)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Dbn1tm1b(KOMP)Wtsi/Dbn1+
(C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi)
increased CD8-positive, alpha-beta T cell number J:211773
DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell activation J:119847
abnormal T cell physiology J:119847
decreased IgG1 level J:119847
decreased IgM level J:119847
decreased immunoglobulin level J:119847
decreased interleukin-2 secretion J:119847
decreased T cell proliferation J:119847
immune system phenotype J:119847
Dbnltm1Jwnd/Dbnl+
(involves: BALB/c)
increased spleen weight J:109363
Dbnltm1Jwnd/Dbnltm1Jwnd
(involves: BALB/c)
increased spleen weight J:109363
Dbr1Gt(YTA280)Byg/Dbr1+
(involves: 129P2/OlaHsd)
abnormal class switch recombination J:223318
Dcaf8em1(IMPC)Ccpcz/Dcaf8em1(IMPC)Ccpcz
(C57BL/6N-Dcaf8em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Dcaf12em1(IMPC)Ccpcz/Dcaf12em1(IMPC)Ccpcz
(C57BL/6N-Dcaf12em1(IMPC)Ccpcz/Ccpcz)
decreased CD8-positive, naive alpha-beta T cell number J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Dcbld2tm1a(KOMP)Wtsi/Dcbld2tm1a(KOMP)Wtsi
(C57BL/6N-Dcbld2tm1a(KOMP)Wtsi/Wtsi)
increased anti-nuclear antigen antibody level J:211773
DccTg(H2-Kb-Jak2*V617F)1Shmd/Dcc+
(involves: C57BL/6 * DBA/2)
abnormal neutrophil morphology J:130189
abnormal spleen morphology J:130189
decreased spleen white pulp amount J:130189
enlarged spleen J:130189
increased granulocyte number J:130189
increased leukocyte cell number J:130189
increased spleen red pulp amount J:130189
increased spleen weight J:130189
myeloid hyperplasia J:130189
Dcctm1b(NCOM)Mfgc/Dcc+
(C57BL/6N-Dcctm1b(NCOM)Mfgc/Tcp)
increased neutrophil cell number J:211773
Dckm1Btlr/Dck+
(C57BL/6J-Dckm1Btlr)
decreased B cell number J:236696
Dckm1Btlr/Dckm1Btlr
(C57BL/6J-Dckm1Btlr)
decreased B cell number J:236696
decreased CD4-positive, alpha-beta T cell number J:236696
decreased IgG level J:236696
decreased response to antigen J:236696
increased CD8-positive, alpha-beta T cell number J:236696
increased IgE level J:236696
increased macrophage cell number J:236696
Dckmemi/Dckmemi
(C57BL/6J-Dckmemi)
abnormal myeloid leukocyte morphology J:184080
abnormal response to infection J:184080
abnormal T cell differentiation J:184080
decreased B cell number J:184080
decreased CD4-positive, alpha-beta T cell number J:184080
enlarged spleen J:184080
increased effector memory CD4-positive, alpha-beta T cell number J:184080
increased effector memory CD8-positive, alpha-beta T cell number J:184080
increased T cell apoptosis J:184080
increased T cell proliferation J:184080
small thymus J:184080
thymus hypoplasia J:184080
Dcktm1.1Radu/Dcktm1.1Radu
(involves: 129S4/SvJae * BALB/cJ * C57BL/6 * C57BL/6J)
abnormal double-negative T cell morphology J:158373
abnormal peripheral lymph node morphology J:158373
abnormal spleen morphology J:158373
abnormal T cell differentiation J:158373
abnormal thymus morphology J:158373
absent spleen white pulp J:158373
decreased B cell number J:158373
decreased double-positive T cell number J:158373
decreased pre-B cell number J:158373
decreased T cell number J:158373
increased double-negative T cell number J:158373
increased pro-B cell number J:158373
increased spleen weight J:158373
thymus hypoplasia J:158373
Dclk1tm1a(EUCOMM)Wtsi/Dclk1+
(C57BL/6N-Dclk1tm1a(EUCOMM)Wtsi/Wtsi)
increased anti-nuclear antigen antibody level J:211773
Dclk1tm1a(EUCOMM)Wtsi/Dclk1tm1a(EUCOMM)Wtsi
(C57BL/6N-Dclk1tm1a(EUCOMM)Wtsi/Wtsi)
increased anti-nuclear antigen antibody level J:211773
Dclre1atm1Rleg/Dclre1atm1Rleg
(involves: 129S7/SvEvBrd)
immune system phenotype J:102381
increased susceptibility to bacterial infection J:102381
Dclre1cm1Brck/Dclre1cm1Brck
(involves: C3H * C57BL/6)
absent B cells J:207533
absent T cells J:207533
Dclre1cm1Brck/Dclre1cm1Brck
(involves: C57BL/6)
absent B cells J:207533
absent CD4-positive, alpha-beta T cells J:207533
absent CD8-positive, alpha-beta T cells J:207533
decreased DN1 thymic pro-T cell number J:207533
decreased DN4 thymocyte number J:207533
decreased double-positive T cell number J:207533
decreased pre-B cell number J:207533
immune system phenotype J:207533
Dclre1cm1Btlr/Dclre1cm1Btlr
(C57BL/6J-Dclre1cm1Btlr)
decreased B cell number J:217790
decreased IgM level J:217790
decreased response to antigen J:217790
decreased single-positive T cell number J:217790
decreased T cell number J:217790
impaired humoral immune response J:217790
increased macrophage cell number J:217790
increased neutrophil cell number J:217790
increased NK cell number J:217790
Dclre1cM2Btlr/Dclre1cM2Btlr
(C57BL/6J-Dclre1cM2Btlr)
decreased CD4-positive, alpha-beta T cell number J:265131
decreased CD8-positive, naive alpha-beta T cell number J:265131
decreased single-positive T cell number J:265131
decreased T cell number J:265131
increased central memory CD8 positive, alpha-beta T cell number J:265131
increased effector memory CD4-positive, alpha-beta T cell number J:265131
increased effector memory CD8-positive, alpha-beta T cell number J:265131
Dclre1cm3Btlr/Dclre1cm3Btlr
(C57BL/6J-Dclre1cm3Btlr)
decreased B cell number J:265132
decreased B-1 B cell number J:265132
decreased CD4-positive, alpha-beta T cell number J:265132
decreased CD8-positive, alpha-beta T cell number J:265132
decreased CD8-positive, naive alpha-beta T cell number J:265132
decreased NK T cell number J:265132
decreased single-positive T cell number J:265132
decreased T cell number J:265132
increased central memory CD4-positive, alpha-beta T cell number J:265132
increased effector memory CD4-positive, alpha-beta T cell number J:265132
increased effector memory CD8-positive, alpha-beta T cell number J:265132
Dclre1ctm1.1Fwa/Dclre1ctm1.1Fwa
(involves: 129S6/SvEvTac * C57BL/6)
arrested B cell differentiation J:80995
arrested T cell differentiation J:80995
Dclre1ctm1.1Jpdv/Dclre1ctm1.1Jpdv
(involves: 129P1/ReJ)
abnormal B cell differentiation J:137743
abnormal T cell receptor V(D)J recombination J:194422
arrested T cell differentiation J:137712
Dclre1ctm1Fwa/Dclre1ctm1Fwa
(involves: 129S6/SvEvTac * C57BL/6)
absent immature B cells J:80995
arrested B cell differentiation J:80995
arrested T cell differentiation J:80995
decreased thymocyte number J:80995
Dclre1ctm1Fwa/Dclre1ctm1Fwa
(involves: 129S6/SvEvTac)
abnormal T cell receptor beta chain V(D)J recombination J:147864
absent B cells J:147864
arrested B cell differentiation J:147864
decreased CD4-positive, alpha-beta T cell number J:147864
decreased CD8-positive, alpha-beta T cell number J:147864
decreased double-positive T cell number J:147864
decreased thymocyte number J:147864
spleen hypoplasia J:147864
Dclre1ctm1Jsek/Dclre1ctm1Jsek
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immunoglobulin heavy chain V(D)J recombination J:147864
abnormal T cell receptor beta chain V(D)J recombination J:147864
decreased B cell number J:147864
decreased CD4-positive, alpha-beta T cell number J:147864
decreased CD8-positive, alpha-beta T cell number J:147864
decreased double-positive T cell number J:147864
decreased pre-B cell number J:147864
decreased thymocyte number J:147864
increased pro-B cell number J:147864
spleen hypoplasia J:147864
Dclre1ctm2.1Jpdv/Dclre1ctm2.2Jpdv
Tg(Cr2-cre)3Cgn/0

(involves: 129S2/SvPas * C57BL/6)
abnormal class switch recombination J:153841
immune system phenotype J:153841
Dclre1ctm2.2Jpdv/Dclre1ctm2.2Jpdv
(B6.129S2-Dclre1ctm2.2Jpdv)
abnormal mononuclear cell morphology J:153841
absent immature B cells J:153841
arrested B cell differentiation J:153841
arrested T cell differentiation J:153841
decreased CD4-positive, alpha-beta T cell number J:153841
decreased CD8-positive, alpha-beta T cell number J:153841
decreased double-positive T cell number J:153841
decreased mature B cell number J:153841
decreased splenocyte number J:153841
decreased thymocyte number J:153841
Dclre1ctm2Mcow/Dclre1ctm2Mcow
(involves: 129/Sv * C57BL/6)
abnormal leukocyte physiology J:96535
abnormal lymph node morphology J:96535
abnormal spleen B cell follicle morphology J:96535
absent thymus cortex J:96535
arrested B cell differentiation J:96535
arrested T cell differentiation J:96535
decreased B cell proliferation J:96535
decreased lymphocyte cell number J:96535
decreased T cell proliferation J:96535
decreased thymocyte number J:96535
decreased thymus weight J:96535
small lymph nodes J:96535
small spleen J:96535
Dcntm1Ioz/Dcn+
(either: C.Cg-Dcntm1Ioz or C3.Cg-Dcntm1Ioz)
decreased susceptibility to bacterial infection J:68640
Dcntm1Ioz/Dcntm1Ioz
(involves: 129S1/Sv * 129X1/SvJ * Black Swiss)
immune system phenotype J:39212
tubular nephritis J:75298
Dcntm1Ioz/Dcntm1Ioz
(either: C.Cg-Dcntm1Ioz or C3.Cg-Dcntm1Ioz)
decreased susceptibility to bacterial infection J:68640
Dcntm1Ioz/Dcntm1Ioz
(C.129(Cg)-Dcntm1Ioz)
abnormal humoral immune response J:92428
Dcntm1Ioz/Dcntm1Ioz
Trp53tm1Brd/Trp53tm1Brd

(involves: 129/Sv * Black Swiss * C57BL/6)
enlarged thymus J:53511
thymus hyperplasia J:53511
Dcstamptm1Suda/Dcstamptm1Suda
(Not Specified)
abnormal macrophage physiology J:100555
abnormal osteoclast differentiation J:100555
abnormal osteoclast physiology J:100555
Dctn1tm2.1Cai/Dctn1tm2.1Cai
Tg(Thy1-cre)1Vln/?

(involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB/N)
microgliosis J:264431
Dcun1d1Gt(RRR261)Byg/Dcun1d1Gt(RRR261)Byg
(involves: 129P2/OlaHsd)
lymphoid hypoplasia J:262901
spleen hypoplasia J:262901
Ddb1em1(IMPC)Ccpcz/Ddb1+
(C57BL/6N-Ddb1em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Ddctm1.1Rhrs/Ddctm1.1Rhrs
Tg(Ggt1-cre)M3Egn/0

(involves: 129 * C57BL/6 * SJL)
tubulointerstitial nephritis J:175630
Ddctm1.1Rhrs/Ddctm1.1Rhrs
Tg(Ggt1-cre)M3Egn/0

(129.Cg-Ddctm1.1Rhrs Tg(Ggt1-cre)M3Egn)
tubulointerstitial nephritis J:175630
Ddit3tm1Dron/Ddit3tm1Dron
(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
decreased susceptibility to Retroviridae infection J:112354
Ddit3tm1Dron/Ddit3tm1Dron
(B6.129-Ddit3tm1Dron)
abnormal macrophage activation involved in immune response J:153833
decreased macrophage apoptosis J:153833
Ddit3tm1Dron/Ddit3tm1Dron
Tg(Col2a1-rtTA,tetO-COMP*)2Jath/0

(involves: 129X1/SvJ * 129S1/Sv * C57BL/6)
decreased inflammatory response J:233238
Ddit3tm2.1Dron/Ddit3tm2.1Dron
(B6.129S(Cg)-Ddit3tm2.1Dron/J)
abnormal T cell morphology J:214136
white adipose tissue inflammation J:214136
Ddosttm1.1(KOMP)Vlcg/Ddost+
(C57BL/6N-Ddosttm1.1(KOMP)Vlcg/Ucd)
enlarged lymph nodes J:211773
small spleen J:211773
Ddr1tm1Wfv/Ddr1tm1Wfv
Ldlrtm1Her/Ldlrtm1Her

(involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ)
decreased macrophage cell number J:149015
Ddrgk1tm1c(EUCOMM)Hmgu/Ddrgk1tm1c(EUCOMM)Hmgu
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/6N)
decreased granulocyte number J:231701
decreased lymphocyte cell number J:231701
decreased monocyte cell number J:231701
Ddx19bem1Chaw/Ddx19b+
(C57BL/6-Ddx19bem1Chaw)
increased interferon-alpha secretion J:289833
increased interferon-beta secretion J:289833
Ddx23em1(IMPC)Wtsi/Ddx23+
(C57BL/6N-Ddx23em1(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Ddx41tm1.1Arte/Ddx41tm1.1Arte
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6N)
immune system phenotype J:265023
increased susceptibility to Retroviridae infection J:265023
Ddx41tm1.1Arte/Ddx41tm1.1Arte
Tg(Itgax-cre)1-1Reiz/0

(involves: C57BL/6 * C57BL/6N * CBA)
immune system phenotype J:265023
increased susceptibility to Retroviridae infection J:265023
Ddx46em1(IMPC)Tcp/Ddx46+
(C57BL/6N-Ddx46em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Ddx46em1Caox/Ddx46+
(involves: C57BL/6J)
abnormal innate immunity J:271836
abnormal macrophage physiology J:271836
decreased susceptibility to Riboviria infection J:271836
increased circulating interferon-beta level J:271836
increased interferon-beta secretion J:271836
increased interleukin-1 beta secretion J:271836
increased interleukin-6 secretion J:271836
increased macrophage cytokine production J:271836
increased tumor necrosis factor secretion J:271836
Ddx52tm1a(EUCOMM)Wtsi/Ddx52+
(C57BL/6N-Ddx52tm1a(EUCOMM)Wtsi/Ics)
decreased NK cell number J:165965
Ddx60tm1b(EUCOMM)Wtsi/Ddx60tm1b(EUCOMM)Wtsi
(involves: C57BL/6N)
decreased circulating interferon-beta level J:228452
increased circulating interferon-alpha level J:228452
increased susceptibility to Riboviria infection J:228452
increased susceptibility to Riboviria infection induced morbidity/mortality J:228452
Ddx60tm1b(EUCOMM)Wtsi/Ddx60tm1b(EUCOMM)Wtsi
Mavstm1Tsse/Mavstm1Tsse

(involves: 129 * C57BL/6N)
increased susceptibility to Riboviria infection induced morbidity/mortality J:228452
Deddtm1Tmiy/Deddtm1Tmiy
(B6.Cg-Deddtm1Tmiy)
decreased spleen weight J:119734
Def6Gt(OST307148)Lex/Def6Gt(OST307148)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal cytokine secretion J:106469
abnormal spleen germinal center morphology J:106469
decreased T cell apoptosis J:106469
enlarged lymph nodes J:106469
enlarged spleen J:106469
increased anti-nuclear antigen antibody level J:106469
increased IgG level J:106469
increased immature B cell number J:106469
increased immunoglobulin level J:106469
increased memory T cell number J:106469
increased T cell number J:106469
Defb1tm1Hgu/Defb1tm1Hgu
(involves: 129P2/OlaHsd * C57BL/6N)
immune system phenotype J:76528
Defb1tm1Jmw/Defb1+
(B6.129S5-Defb1tm1Jmw)
increased susceptibility to bacterial infection J:76529
Defb1tm1Jmw/Defb1tm1Jmw
(B6.129S5-Defb1tm1Jmw)
increased susceptibility to bacterial infection J:76529
Defb3tm1Lex/Defb3tm1Lex
(B6;129S5-Defb3tm1Lex/Mmucd)
increased susceptibility to bacterial infection J:168725
Defb3tm1Xen/Defb3tm1Xen
(involves: C57BL/6)
increased incidence of corneal inflammation J:199719
increased neutrophil cell number J:199719
increased susceptibility to fungal infection J:199719
Defb14tm1Wme/Defb14tm1Wme
(B6.129P2-Defb14tm1Wme)
immune system phenotype J:180788
Del(1)1Brk/Del(1)1Brk
(involves: 129S6/SvEvTac * C57BL/6J * CBA/J)
abnormal spleen morphology J:100202
abnormal spleen white pulp morphology J:100202
enlarged spleen J:100202
increased leukocyte cell number J:100202
increased spleen red pulp amount J:100202
Del(1Aim2-Ifi205)1Stsn/+
Trex1tm1Tld/Trex1tm1Tld

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N)
heart inflammation J:234263
increased autoantibody level J:234263
increased inflammatory response J:234263
kidney inflammation J:234263
myositis J:234263
stomach inflammation J:234263
Del(1Aim2-Ifi205)1Stsn/Del(1Aim2-Ifi205)1Stsn
(B6(129S4)-Del(1Aim2-Ifi205)1Stsn)
abnormal interferon secretion J:234263
decreased interleukin-1 beta secretion J:234263
decreased macrophage apoptosis J:234263
Del(1Aim2-Ifi205)1Stsn/Del(1Aim2-Ifi205)1Stsn
(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N)
stomach inflammation J:234263
Del(1Aim2-Ifi205)1Stsn/Del(1Aim2-Ifi205)1Stsn
Trex1tm1Tld/Trex1tm1Tld

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N)
heart inflammation J:234263
increased autoantibody level J:234263
increased inflammatory response J:234263
kidney inflammation J:234263
myositis J:234263
stomach inflammation J:234263
Del(2Duoxa2-Duoxa1)1Sref/Del(2Duoxa2-Duoxa1)1Sref
(involves: 129S6/SvEvTac * C57BL/6J)
decreased spleen weight J:205165
Del(3Cd1d2-Cd1d1)1Crw/Del(3Cd1d2-Cd1d1)1Crw
(involves: 129S4/SvJae * C57BL/6)
abnormal antigen presentation J:174337
abnormal NK T cell physiology J:112657
decreased CD4-positive, alpha-beta T cell number J:174337
decreased interleukin-4 secretion J:39749
decreased NK T cell number J:112657, J:174337, J:39749, J:76976
Del(3Cd1d2-Cd1d1)1Crw/Del(3Cd1d2-Cd1d1)1Crw
TcraLn1Ogu/Tcra+

(involves: 129/Sv * C57BL/6)
abnormal NK T cell morphology J:152041
Del(3Cd1d2-Cd1d1)1Crw/Del(3Cd1d2-Cd1d1)1Crw
Tg(TcraAV19AJ33)1Shima/0

(involves: 129S4/SvJae * C57BL/6)
abnormal NK T cell morphology J:112657
decreased susceptibility to experimental autoimmune encephalomyelitis J:112657
increased interleukin-10 secretion J:112657
Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp
(either: B6NTac.129S6-Del(3Cd1d2-Cd1d1)1Sbp or (involves: 129S6/SvEvTac * C57BL/6NTac))
abnormal immune tolerance J:58315
Del(3Cd1d2-Cd1d1)1Sbp/Del(3Cd1d2-Cd1d1)1Sbp
(involves: 129S6/SvEvTac)
abnormal dendritic cell antigen presentation J:151699
decreased NK T cell number J:151699
Del(3Gbp2-ps-Gbp5)1Ktak/Del(3Gbp2-ps-Gbp5)1Ktak
(involves: C57BL/6)
immune system phenotype J:187397
increased susceptibility to parasitic infection J:187397
increased susceptibility to parasitic infection induced morbidity/mortality J:187397
Del(4C4-C5)1Lap/+
(involves: 129S6/SvEvTac)
enlarged spleen J:158126
Del(4C4-C5)1Lap/Del(4C4-C5)1Lap
(involves: 129S6/SvEvTac)
enlarged spleen J:158126
Del(4D4Mit190-D4Mit51)2Aam/+
(involves: 129S7/SvEvBrd)
spleen hyperplasia J:121726
Del(6Ephb6-Trpv6)1Mhed/+
(involves: 129S/SvEv)
dermatitis J:133151
Del(6Ephb6-Trpv6)1Mhed/Del(6Ephb6-Trpv6)1Mhed
(involves: 129S/SvEv)
dermatitis J:133151
Del(6Gimap5-Gimap3)1Yout/Del(6Gimap5-Gimap3)1Yout
(involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj)
abnormal T cell physiology J:209926
decreased B cell number J:209926
decreased NK cell number J:209926
decreased T cell number J:209926
Del(6Snca)1Slab/Del(6Snca)1Slab
Tg(Th-SNCA*)1Mgsp/0

(involves: C57BL/6J * C57BL/6JOlaHsd * CBA/Ca)
abnormal microglial cell morphology J:108310
brain inflammation J:108310
Del(7)Tyrc-3H/Del(7)Tyrc-3H
(involves: 101/H * C3H/HeH)
abnormal thymus morphology J:5063
Del(7Ifitm5-Ifitm6)1Masu/+
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:137940
Del(7Mrgpra2a-Mrgpra2b)1Xzd/Del(7Mrgpra2a-Mrgpra2b)1Xzd
(C57BL/6J-Del(7Mrgpra2a-Mrgpra2b)1Xzd)
abnormal neutrophil physiology J:332494
decreased interleukin-1 beta secretion J:332494
increased susceptibility to bacterial infection J:332494
Del(7Pira1-Lilra6)1Fgla/Del(7Pira1-Lilra6)1Fgla
(involves: C57BL/6)
decreased susceptibility to graft versus host disease J:290663
Del(7Pira1-Lilra6)1Fgla/Del(7Pira1-Lilra6)1Fgla
Il2rgtm1Wjl/Il2rgtm1Wjl
Rag2tm1Fwa/Rag2tm1Fwa

(involves: C57BL/6J * C57BL/6NTac)
abnormal response to transplant J:290663
Del(8A4-B3)7H/+
(involves: 101/H * C3H/HeH)
abnormal lymphatic vessel morphology J:123074
Del(8Ddx19a-Ddx19b)1Chaw/+
(C57BL/6-Del(8Ddx19a-Ddx19b)1Chaw)
decreased susceptibility to Picornaviridae infection J:289833
decreased susceptibility to Picornaviridae infection induced morbidity/mortality J:289833
increased interferon-alpha secretion J:289833
increased interferon-beta secretion J:289833
Del(8Ddx19a-Ddx19b)2Chaw/+
(C57BL/6-Del(8Ddx19a-Ddx19b)2Chaw)
increased interferon-alpha secretion J:289833
increased interferon-beta secretion J:289833
Del(8Defa1-Def)2Xzd/Del(8Defa1-Def)2Xzd
Tg(KRT14-cre)1Amc/0

(involves: C57BL/6J * CBA)
increased susceptibility to bacterial infection J:332494
Del(8Defb1-Defb13)1Jrdo/Del(8Defb1-Defb13)1Jrdo
(involves: 129P2/OlaHsd * C57BL/6N)
immune system phenotype J:204187
Del(9Apoa1-Apoa4)1Hmez/Del(9Apoa1-Apoa4)1Hmez
(involves: 129P2/OlaHsd * C57BL/6)
increased macrophage derived foam cell number J:109005
Del(9Casp1-Casp4)1Bhk/Del(9Casp1-Casp4)1Bhk
(129-Del(9Casp1-Casp4)1Bhk)
abnormal macrophage physiology J:189777
decreased interleukin-1 alpha secretion J:189777
decreased interleukin-1 beta secretion J:189777
Del(9Cd3g-Cd3d)1Cpt/Del(9Cd3g-Cd3d)1Cpt
(involves: 129S4/SvJae * C57BL/6)
absent gamma-delta T cells J:76991
arrested T cell differentiation J:76991
decreased alpha-beta T cell number J:76991
thymus hypoplasia J:76991
Del(9Hspb2-Cryab)1Wawr/Del(9Hspb2-Cryab)1Wawr
(involves: 129S4/SvJae)
osteoarthritis J:72926
Del(10Prmt2-Col6a1)1Yah/+
(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal cytokine level J:167506
abnormal macrophage physiology J:167506
lung inflammation J:167506
respiratory system inflammation J:167506
Del(10Prtn3-Elane)1Deje/Del(10Prtn3-Elane)1Deje
(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ)
abnormal neutrophil physiology J:137674
immune system phenotype J:137674
impaired neutrophil recruitment J:137674
Del(11Cxcl16-Zmynd15)1Ifc/Del(11Cxcl16-Zmynd15)1Ifc
(B6.129S-Ldlrtm1Her Del(11Cxcl16-Zmynd15)1Ifc)
abnormal macrophage physiology J:123851
Del(11Hoxb3-Hoxb4)1Karl/Del(11Hoxb3-Hoxb4)1Karl
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal spleen morphology J:83563
decreased spleen weight J:83563
spleen hypoplasia J:83563
Del(11Hoxb3-Hoxb4)1Karl/Del(11Hoxb3-Hoxb4)1Karl
Hoxa9tm1Mrc/Hoxa9tm1Mrc

(involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6)
decreased spleen weight J:126371
spleen hypoplasia J:126371
Del(11Jmjd6-Mettl23)1Ysfk/Del(11Jmjd6-Mettl23)1Ysfk
(involves: C57BL/6)
abnormal thymus development J:90288
impaired macrophage chemotaxis J:90288
impaired macrophage phagocytosis J:90288
thymus hypoplasia J:90288
Del(11Nlrp1a-Nlrp1c-ps)1Smas/Del(11Nlrp1a-Nlrp1c-ps)1Smas
(Not Specified)
decreased neutrophil cell number J:191055
increased susceptibility to Riboviria infection J:191055
Del(11Stat5a-Stat5b)1Mam/Del(11Stat5a-Stat5b)1Mam
(involves: 129 * 129S6/SvEvTac * C57BL/6)
absent gamma-delta T cells J:122463
arrested B cell differentiation J:122463
decreased B cell number J:122463
decreased CD8-positive, alpha-beta T cell number J:122463
small lymph nodes J:122463
small spleen J:122463
small thymus J:122463
Del(13Naip1-Naip5)1Vnce/Del(13Naip1-Naip5)1Vnce
(involves: C57BL/6)
decreased inflammatory response J:294930
Del(13Naip1-Naip5)1Vnce/Del(13Naip1-Naip5)1Vnce
Nlrc4em2Vnce/Nlrc4em2Vnce

(involves: C57BL/6)
decreased inflammatory response J:294930
Del(13Naip1-Naip5)1Vnce/Del(13Naip1-Naip5)1Vnce
Nlrp3tm1Vmd/Nlrp3tm1Vmd

(involves: C57BL/6J * C57BL/6N)
decreased inflammatory response J:294930
Del(14Ltb4r2-Ltb4r1)1Bodd/+
(involves: 129S4/SvJaeSor * C57BL/6)
decreased susceptibility to induced arthritis J:131779
Del(14Ltb4r2-Ltb4r1)1Bodd/Del(14Ltb4r2-Ltb4r1)1Bodd
(involves: 129S4/SvJaeSor * C57BL/6)
decreased susceptibility to induced arthritis J:131779
immune system phenotype J:131779
impaired neutrophil chemotaxis J:163271
Del(14Trim13-Dleu2)4Rdf/Del(14Trim13-Dleu2)4Rdf
(involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
abnormal B cell proliferation J:156946
increased B cell number J:156946
increased B-1a cell number J:156946
increased spleen white pulp amount J:156946
Del(14Trim13-Rnaseh2b)6Rdf/+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
abnormal lymphopoiesis J:179879
increased B cell number J:179879
Del(15Rr357-Rr303293)2Jta/Del(15Rr357-Rr303293)2Jta
(involves: C57BL/6)
immune system phenotype J:257088
Del(15Rr316124-Rr313939)2Fsp/+
Myctm1Atp/Myc+

(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:257739
decreased granulocyte number J:257739
Del(15Rr316124-Rr313939)2Fsp/+
Rr331em1Fsp/Rr331+

(involves: C57BL/6)
decreased B cell number J:257739
increased pre-B cell number J:257739
Del(15Rr316124-Rr313939)2Fsp/+
Rr307328em1Fsp/Rr307328+

(involves: C57BL/6)
decreased B cell number J:257739
increased pre-B cell number J:257739
Del(15Rr316124-Rr313939)2Fsp/Del(15Rr316124-Rr313939)2Fsp
(Not Specified)
decreased B cell number J:257739
decreased granulocyte number J:257739
Del(16Dgcr2-Hira)1Rak/+
(involves: 129/Sv * 129S6/SvEvTac * C57BL/6 * FVB/N * SJL)
immune system phenotype J:67796
Del(16Es2el-Ufd1l)217Bld/+
(involves: 129S7/SvEvBrd * C57BL/6)
immune system phenotype J:57757
Del(16Pi4ka-Hira)1Atai/+
(C57BL/6N-Del(16Pi4ka-Hira)1Atai)
thymus hypoplasia J:285407
Del(17Btnl1-Btnl6)1Ahay/Del(17Btnl1-Btnl6)1Ahay
(involves: BALB/c * C57BL/6J)
decreased CD4-positive, gamma-delta intraepithelial T cell number J:291989
Del(17Trem1-Trem3)1Jkt/Del(17Trem1-Trem3)1Jkt
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal chemokine level J:194295
abnormal circulating chemokine level J:194295
abnormal cytokine level J:194295
abnormal cytokine secretion J:194295
impaired neutrophil chemotaxis J:194295
increased circulating interleukin-1 alpha level J:194295
increased circulating interleukin-6 level J:194295
increased circulating interleukin-10 level J:194295
increased circulating tumor necrosis factor level J:194295
increased interleukin-1 alpha secretion J:194295
increased interleukin-1 beta secretion J:194295
increased interleukin-6 secretion J:194295
increased interleukin-10 secretion J:194295
increased interleukin-17 secretion J:194295
increased susceptibility to bacterial infection J:194295
increased susceptibility to bacterial infection induced morbidity/mortality J:194295
Del(18Pcdhg)1Xzw/Del(18Pcdhg)1Xzw
(Not Specified)
microgliosis J:188341
Del(19Poll-Dcpd)1Nmt/Del(19Poll-Dcpd)1Nmt
(involves: 129P2/OlaHsd)
sinus inflammation J:75779
Dennd1btm1.1Achn/Dennd1btm1.1Achn
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
lymph node hyperplasia J:229307
Dennd1btm1.2Achn/Dennd1btm1.2Achn
(involves: C57BL/6)
abnormal interleukin secretion J:229307
abnormal T cell number J:229307
abnormal T-helper 2 physiology J:229307
immune system phenotype J:229307
lymph node hyperplasia J:229307
Dennd5bem1(IMPC)Tcp/Dennd5bem1(IMPC)Tcp
(C57BL/6N-Dennd5bem1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Dennd5bm1Anu/Dennd5bm1Anu
(C57BL/6NCrlAnu-Dennd5bm1Anu)
immune system phenotype J:104190
Dennd10em1(IMPC)Ccpcz/Dennd10em1(IMPC)Ccpcz
(C57BL/6NCrl-Dennd10em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Derm1NC/Nga/Derm1NC/Nga
(involves: MSM/Ms * NC/Nga)
dermatitis J:68698
DermsBALB/cByJ/?
(involves: BALB/cByJ * C3H/HeJ * C57BL/6J * DBA/2J)
dermatitis J:80574
DermsDBA/2J/?
(involves: BALB/cByJ * C3H/HeJ * C57BL/6J * DBA/2J)
dermatitis J:80574
Dexiem1Kslr/Dexiem1Kslr
(NOD/ShiLtJ-Dexiem1Kslr)
immune system phenotype J:285312
Dffbem1(IMPC)Wtsi/Dffbem1(IMPC)Wtsi
(C57BL/6N-Dffbem1(IMPC)Wtsi/Wtsi)
increased anti-nuclear antigen antibody level J:211773
Dffbtm1Osa/Dffbtm1Osa
Dnase2atm1Osa/Dnase2atm1Osa

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal T cell differentiation J:81474
abnormal thymus morphology J:81474
decreased double-positive T cell number J:81474
increased double-negative T cell number J:81474
small thymus J:81474
thymus hypoplasia J:81474
Dgcr2tm1b(EUCOMM)Wtsi/Dgcr2tm1b(EUCOMM)Wtsi
(C57BL/6N-Dgcr2tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Dgkatm1Xpz/Dgkatm1Xpz
(involves: 129 * C57BL/6)
abnormal lymphocyte anergy J:113564
increased interleukin-2 secretion J:113564
increased T cell number J:113564
Dgkatm1Xpz/Dgkatm1Xpz
Dgkztm1Gak/Dgkztm1Gak

(involves: 129 * 129X1/SvJ * C57BL/6)
abnormal T cell differentiation J:113564
abnormal thymocyte activation J:113564
Dgkztm1Gak/Dgkztm1Gak
(involves: 129X1/SvJ * C57BL/6)
abnormal cytokine level J:293120
abnormal cytokine secretion J:293120
abnormal inflammatory response J:293120
abnormal interferon level J:85149
abnormal macrophage physiology J:293120
abnormal T cell activation J:85149
abnormal T cell physiology J:85149
decreased CD4-positive, alpha-beta T cell number J:85149
decreased CD8-positive, alpha-beta T cell number J:85149
decreased interleukin-6 secretion J:293120
decreased susceptibility to induced arthritis J:293120
decreased susceptibility to Riboviria infection J:85149
increased B cell number J:85149
increased T cell proliferation J:85149
Dgkztm1Gak/Dgkztm1Gak
(B6.129X1-Dgkztm1Gak)
abnormal interleukin-2 secretion J:113564
abnormal lymphocyte anergy J:113564
increased T cell number J:113564
Dh/Dh
(Not Specified)
absent spleen J:152370, J:112
Dh/Dh+
(Not Specified)
absent spleen J:152370, J:112
enlarged lymph nodes J:30753
increased granulocyte number J:30753
increased lymphocyte cell number J:30753
Dh/Dh+
(B6.CBA-Dh)
abnormal T cell differentiation J:5834
absent spleen J:5834
decreased immunoglobulin level J:5834
Dh/Dh+
Foxn1nu/Foxn1nu

(involves: N:NIH(S))
abnormal Peyer's patch morphology J:6062
absent spleen J:6062
athymia J:6062
decreased leukocyte cell number J:6062
increased IgA level J:6062
Dh/Dh+
H2d/H2d

(NZB.Cg-Dh)
absent spleen J:12036
decreased B cell proliferation J:12036
decreased IgG1 level J:12036
decreased IgG level J:12036
decreased IgM level J:12036
decreased susceptibility to graft versus host disease J:12036
glomerulonephritis J:12036
increased anti-erythrocyte antigen antibody level J:12036
increased anti-nuclear antigen antibody level J:12036
increased anti-single stranded DNA antibody level J:12036
increased autoantibody level J:12036
increased T cell proliferation J:12036
Dhcr7em1(IMPC)Mbp/Dhcr7+
(C57BL/6N-Dhcr7em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Dhfrorana/Dhfr+
(involves: C57BL/6JAnu)
enlarged spleen J:236197
Dhpstm2c(EUCOMM)Wtsi/Dhpstm2c(EUCOMM)Wtsi
Tg(CAG-cre/Esr1*)5Amc/0

(involves: C57BL/6J * C57BL/6N * CBA * SJL)
decreased spleen red pulp amount J:236582
spleen hypoplasia J:236582
Dhrs4tm1Lex/Dhrs4tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal humoral immune response J:171883
decreased IgG2a level J:171883
Dhrs7bGt(OST255410)Lex/Dhrs7bGt(OST255410)Lex
(B6;129S5-Dhrs7bGt(OST255410)Lex/Mmucd)
thymus atrophy J:171883
Dhx8em1(IMPC)Mbp/Dhx8+
(C57BL/6N-Dhx8em1(IMPC)Mbp/MbpMmucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9+
(involves: FVB/NJ)
immune system phenotype J:207361
Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9+
Igs12tm1Zhu/Igs12tm1Zhu
Ptprca/Ptprcb
Tg(Lck-cre)#Zhu/0

(involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J)
abnormal T cell differentiation J:207361
Dhx15tm1c(EUCOMM)Wtsi/Dhx15tm1c(EUCOMM)Wtsi
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C3H * C57BL/6N)
abnormal B cell differentiation J:284624
decreased B cell number J:284624
decreased B cell proliferation J:284624
decreased pre-B cell number J:284624
decreased spleen weight J:284624
spleen hypoplasia J:284624
Dhx15tm1c(EUCOMM)Wtsi/Dhx15tm1c(EUCOMM)Wtsi
Tg(Cd4-cre)1Cwi/0

(involves: C3H * C57BL/6N * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:284624
decreased CD8-positive, alpha-beta T cell number J:284624
Dhx35tm1b(EUCOMM)Wtsi/Dhx35tm1b(EUCOMM)Wtsi
(C57BL/6N-Dhx35tm1b(EUCOMM)Wtsi/Wtsi)
absent connection between subcutaneous lymph vessels and lymph sac J:239583
Dhx36tm1.2Pmt/Dhx36tm1.2Pmt
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129P2/Ola * 129S4/SvJaeSor * C57BL/6 * C57BL/10 * CBA/Ca)
enlarged spleen J:185179
intermingled spleen red and white pulp J:185179
thymus hypoplasia J:185179
Dhx36tm1.2Pmt/Dhx36tm1.2Pmt
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/Ola * 129S4/SvJaeSor * C57BL/6 * CBA)
abnormal leukopoiesis J:185179
Dhx40tm1b(KOMP)Wtsi/Dhx40tm1b(KOMP)Wtsi
(C57BL/6N-Dhx40tm1b(KOMP)Wtsi/Wtsi)
increased spleen weight J:211773
Dhx58tm1Aki/Dhx58tm1Aki
(involves: 129/Sv * C57BL/6)
decreased circulating interferon-beta level J:156867
decreased interferon-beta secretion J:156867
decreased interleukin-6 secretion J:156867
increased susceptibility to Picornaviridae infection J:156867
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:156867
Dhx58tm1Gnb/Dhx58tm1Gnb
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal interferon secretion J:146113
abnormal susceptibility to Riboviria infection J:146113
decreased interferon-alpha secretion J:146113
decreased interferon-beta secretion J:146113
decreased susceptibility to Riboviria infection J:146113
increased circulating interferon-gamma level J:146113
increased circulating interleukin-12 level J:146113
increased interferon-alpha secretion J:146113
increased interferon-beta secretion J:146113
increased susceptibility to Picornaviridae infection J:146113
Dhx58tm1Itl/Dhx58tm1Itl
(C57BL/6-Dhx58tm1Itl)
decreased interferon-beta secretion J:187386
decreased interferon-gamma secretion J:187386
decreased tumor necrosis factor secretion J:187386
increased susceptibility to Flaviviridae infection J:187386
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:187386
increased T cell apoptosis J:187386
Dhx58tm2.1Aki/Dhx58tm2.1Aki
(involves: 129/Sv * C57BL/6)
decreased interferon-beta secretion J:156867
decreased interleukin-6 secretion J:156867
increased susceptibility to Picornaviridae infection J:156867
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:156867
Diaph1M1Btlr/Diaph1+
(C57BL/6J-Diaph1M1Btlr)
abnormal CD4-positive, alpha-beta T cell number J:254820
abnormal CD8-positive, alpha-beta T cell number J:254820
decreased IgE level J:254820
increased central memory CD4-positive, alpha-beta T cell number J:254820
increased central memory CD8 positive, alpha-beta T cell number J:254820
Diaph1M1Btlr/Diaph1M1Btlr
(C57BL/6J-Diaph1M1Btlr)
abnormal CD4-positive, alpha-beta T cell number J:254820
abnormal CD8-positive, alpha-beta T cell number J:254820
decreased effector memory CD8-positive, alpha-beta T cell number J:254820
decreased IgE level J:254820
increased central memory CD4-positive, alpha-beta T cell number J:254820
increased central memory CD8 positive, alpha-beta T cell number J:254820
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:254820
Diaph1M2Btlr/Diaph1+
(C57BL/6J-Diaph1M2Btlr)
decreased B-1 B cell number J:254819
Diaph1M2Btlr/Diaph1M2Btlr
(C57BL/6J-Diaph1M2Btlr)
decreased B-1 B cell number J:254819
decreased CD8-positive, alpha-beta memory T cell number J:254819
Diaph1m3Btlr/Diaph1m3Btlr
(C57BL/6J-Diaph1m3Btlr)
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254818
decreased CD8-positive, naive alpha-beta T cell number J:254818
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254818
increased CD8-positive, alpha-beta memory T cell number J:254818
increased central memory CD4-positive, alpha-beta T cell number J:254818
increased central memory CD8 positive, alpha-beta T cell number J:254818
increased effector memory CD4-positive, alpha-beta T cell number J:254818
increased effector memory CD8-positive, alpha-beta T cell number J:254818
Diaph1tm1.1Sna/Diaph1tm1.1Sna
(B6.Cg-Diaph1tm1.1Sna)
abnormal humoral immune response J:126090
abnormal leukocyte migration J:126090
decreased CD4-positive, alpha-beta T cell number J:126090
decreased CD8-positive, alpha-beta T cell number J:126090
decreased T cell number J:126090
decreased T cell proliferation J:126090
increased single-positive T cell number J:126090
Diaph1tm1Asal/Diaph1tm1Asal
(involves: 129S1/Sv * C57BL/6)
abnormal lymph node morphology J:124319
abnormal spleen germinal center morphology J:124319
abnormal spleen morphology J:124319
absent spleen white pulp J:124319
decreased lymphocyte cell number J:124319
dermatitis J:124319
increased granulocyte number J:124319
increased leukocyte cell number J:124319
increased monocyte cell number J:124319
increased neutrophil cell number J:124319
increased spleen weight J:124319
Diaph3tm1.1Pji/Diaph3tm1.1Pji
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6J * CBA/J)
enlarged spleen J:293763
Dice1bC57BL/10Sn/Dice1bC57BL/10Sn
(involves: B10.D2-H2d/oSnJ * BALB/cAnN)
decreased susceptibility to parasitic infection J:95337
Dicer1Gt(RRF266)Byg/Dicer1Gt(RRF266)Byg
(involves: 129P2/OlaHsd * C57BL/6)
decreased susceptibility to Riboviria infection J:123635
increased susceptibility to Herpesvirales infection J:123635
increased susceptibility to Riboviria infection J:123635
Dicer1m1Btlr/Dicer1m1Btlr
(C57BL/6J-Dicer1m1Btlr)
decreased CD4-positive, alpha-beta T cell number J:265172
decreased CD8-positive, alpha-beta T cell number J:265172
decreased CD8-positive, naive alpha-beta T cell number J:265172
decreased single-positive T cell number J:265172
decreased T cell number J:265172
increased B-1 B cell number J:265172
increased central memory CD8 positive, alpha-beta T cell number J:265172
increased effector memory CD4-positive, alpha-beta T cell number J:265172
increased effector memory CD8-positive, alpha-beta T cell number J:265172
Dicer1tm1b(EUCOMM)Wtsi/Dicer1+
(C57BL/6N-Dicer1tm1b(EUCOMM)Wtsi/H)
absent spleen J:211773
decreased neutrophil cell number J:211773
Dicer1tm1Bdh/Dicer1+
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129 * C57BL/6 * CBA/J)
abnormal thymus development J:166758
Dicer1tm1Bdh/Dicer1tm1Bdh
Aicdatm1(cre)Njen/Aicda+

(involves: 129 * C57BL/6)
abnormal germinal center B cell physiology J:181782
abnormal humoral immune response J:181782
absent memory B cells J:181782
absent plasma cells J:181782
decreased germinal center B cell number J:181782
decreased immunoglobulin level J:181782
immune system phenotype J:181782
Dicer1tm1Bdh/Dicer1tm1Bdh
Foxp3tm4(YFP/icre)Ayr/Y

(involves: 129S1/Sv * 129X1/SvJ)
blood vessel inflammation J:138683
enlarged lymph nodes J:138683
enlarged spleen J:138683
liver inflammation J:138683
lung inflammation J:138683
Dicer1tm1Bdh/Dicer1tm1Bdh
Foxp3tm4(YFP/icre)Ayr/Foxp3tm4(YFP/icre)Ayr

(involves: 129S1/Sv * 129X1/SvJ)
blood vessel inflammation J:138683
enlarged lymph nodes J:138683
enlarged spleen J:138683
liver inflammation J:138683
lung inflammation J:138683
Dicer1tm1Bdh/Dicer1tm1Bdh
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129 * C57BL/6 * CBA/J)
athymia J:166758
Dicer1tm1Bdh/Dicer1tm1Bdh
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
decreased regulatory T cell number J:138683
Dicer1tm1Bdh/Dicer1tm1Bdh
Tg(Foxp3-EGFP/icre)1aJbs/0

(involves: 129 * NOD/ShiLt)
abnormal CD4-positive, alpha-beta T cell physiology J:138808
abnormal effector T cell morphology J:138808
abnormal lymph node cell ratio J:138808
abnormal regulatory T cell morphology J:138808
abnormal regulatory T cell physiology J:138808
abnormal splenic cell ratio J:138808
decreased regulatory T cell number J:138808
enlarged lymph nodes J:138808
enlarged spleen J:138808
liver inflammation J:138808
lung inflammation J:138808
Dicer1tm1Dli/Dicer1tm1Dli
Tg(Cd4-cre)1Cwi/?

(involves: 129 * C57BL/6 * DBA/2)
abnormal cytotoxic T cell physiology J:100546
abnormal T-helper 1 physiology J:100546
abnormal T-helper 2 physiology J:100546
decreased T cell number J:100546
decreased T cell proliferation J:100546
immune system phenotype J:100546
increased T cell apoptosis J:100546
Dicer1tm1Mmk/Dicer1tm1.1Mmk
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c)
abnormal immunoglobulin V(D)J recombination J:135783
decreased B cell number J:135783
Dicer1tm1Mmk/Dicer1tm1Mmk
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c)
arrested B cell differentiation J:135783
decreased immature B cell number J:135783
decreased mature B cell number J:135783
decreased pre-B cell number J:135783
increased pro-B cell number J:135783
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(IghelMD4)4Ccg/0
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c)
decreased B cell number J:135783
decreased mature B cell number J:135783
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
decreased T cell number J:98192
decreased thymocyte number J:98192
increased gamma-delta T cell number J:98192
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

(involves: 129 * C57BL/6 * CD-1)
abnormal granulocyte differentiation J:158901
abnormal myeloid leukocyte morphology J:158901
abnormal neutrophil morphology J:158901
decreased B cell number J:158901
decreased leukocyte cell number J:158901
enlarged spleen J:158901
Dicer1tm1Tara/Dicer1tm1Tara
Foxn1tm3(cre)Nrm/Foxn1+

(involves: 129P2/OlaHsd * C57BL/6NHsd)
abnormal positive T cell selection J:180783
abnormal thymus cortex morphology J:180783
abnormal thymus epithelium morphology J:180783
abnormal thymus involution J:180783
abnormal thymus medulla morphology J:180783
abnormal thymus morphology J:180783
abnormal thymus physiology J:180783
decreased CD4-positive, alpha-beta T cell number J:180783
decreased CD8-positive, alpha-beta T cell number J:180783
increased susceptibility to induced arthritis J:180783
Dido1tm1Cmar/Dido1+
(involves: 129S1/Sv * 129X1/SvJ)
abnormal splenic cell ratio J:101201
abnormal splenocyte morphology J:101201
increased granulocyte number J:101201
increased monocyte cell number J:101201
increased spleen weight J:101201
spleen hyperplasia J:101201
Dido1tm1Cmar/Dido1tm1Cmar
(involves: 129S1/Sv * 129X1/SvJ)
abnormal splenic cell ratio J:101201
abnormal splenocyte morphology J:101201
immune system phenotype J:101201
increased granulocyte number J:101201
increased monocyte cell number J:101201
increased spleen weight J:101201
increased spleen white pulp amount J:101201
spleen hyperplasia J:101201
Dido1tm3Cmar/Dido1tm3.1Cmar
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+

(involves: 129S/SvEv * C57BL/6)
liver inflammation J:328215
Dip2btm1a(EUCOMM)Wtsi/Dip2b+
(B6JTyr;B6N-Dip2btm1a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:175295
Dip2cem1(IMPC)Tcp/Dip2c+
(C57BL/6N-Dip2cem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
small thymus J:211773
Dipk2bem1(IMPC)Mbp/Dipk2bem1(IMPC)Mbp
(C57BL/6N-Dipk2bem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Dis3tm1.1Uba/Dis3tm1.1Uba
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac)
abnormal B cell morphology J:302856
abnormal class switch recombination J:302856
Disc1em1(IMPC)Mbp/Disc1em1(IMPC)Mbp
(C57BL/6N-Disc1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
Disp3em1(IMPC)Mbp/Disp3em1(IMPC)Mbp
(C57BL/6N-Disp3em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Dkc1tm1.1Pjma/Y
(B6.129X1(FVB)-Dkc1tm1.1Pjma)
decreased B cell number J:217050
decreased T cell number J:217050
Dkc1tm1Ppp/Y
(involves: 129S1/Sv)
abnormal spleen morphology J:81054
decreased B cell number J:81054
decreased leukocyte cell number J:81054
decreased lymphocyte cell number J:81054
decreased pre-B cell number J:81054
decreased spleen red pulp amount J:81054
decreased spleen white pulp amount J:81054
enlarged spleen J:81054
lung inflammation J:81054
Dkc1tm1Ppp/Dkc1+
(involves: 129S1/Sv)
abnormal immune system cell morphology J:81054
abnormal immune system organ morphology J:81054
Dkk2tm1Dwu/Dkk2tm1Dwu
(involves: 129)
abnormal osteoclast differentiation J:100858
increased osteoclast cell number J:100858
Dkk3tm1Cni/Dkk3tm1Cni
(involves: 129X1/SvJ * C57BL/6)
decreased NK cell number J:106922
increased IgM level J:106922
Dlg1tm1Rlh/Dlg1tm1Rlh
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:191788
abnormal cytokine secretion J:191788
abnormal T-helper 1 physiology J:191788
abnormal T-helper 2 physiology J:191788
decreased interferon-gamma secretion J:191788
decreased interleukin-2 secretion J:191788
decreased tumor necrosis factor secretion J:191788
increased interleukin-4 secretion J:191788
increased interleukin-5 secretion J:191788
Dlgap2em1(IMPC)Mhzh/Dlgap2em1(IMPC)Mhzh
(C57BL/6N-Dlgap2em1(IMPC)Mhzh/Mhzh)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
Dlk1tm1.1Jvs/Dlk1+
Myf5tm3(cre)Sor/Myf5+

(involves: 129P2/SvPas * 129S4/SvJaeSor * C57BL/6 * FVB/N)
increased inflammatory response J:167124
Dlk1tm1Srba/Dlk1tm1Srba
(involves: 129X1/SvJ * C57BL/6)
abnormal B cell number J:145076
abnormal spleen B cell follicle morphology J:145076
abnormal spleen marginal zone morphology J:145076
decreased immature B cell number J:145076
decreased mature B cell number J:145076
increased IgG1 level J:145076
increased IgG2a level J:145076
increased IgG2b level J:145076
increased IgG2c level J:145076
increased IgG3 level J:145076
increased IgM level J:145076
increased immature B cell number J:145076
increased immunoglobulin level J:145076
increased marginal zone B cell number J:145076
increased transitional stage B cell number J:145076
Dll1m1Mhda/Dll1+
(C3HeB/FeJ-Dll1m1Mhda)
immune system phenotype J:150183
Dll1tm1Gos/Dll1+
(C3Fe.129-Dll1tm1Gos)
decreased B-1 B cell number J:150183
decreased CD4-positive, alpha-beta T cell number J:150183
decreased CD8-positive, alpha-beta T cell number J:150183
decreased IgA level J:150183
decreased IgG1 level J:150183
decreased IgG2b level J:150183
decreased IgG3 level J:150183
increased B cell number J:150183
increased CD8-positive, alpha-beta T cell number J:150183
Dll1tm1Gos/Dll1+
(involves: 129S1/Sv * 129X1/SvJ)
decreased CD4-positive, alpha-beta T cell number J:150183
increased B cell number J:150183
Dll1tm1Mjo/Dll1tm1Mjo
Tg(KRT5-cre)1Tak/?
Tg(Mx1-cre)1Cgn/?

(involves: 129 * C3H * C57BL/6 * CBA)
immune system phenotype J:90630
Dll1tm1Mjo/Dll1tm1Mjo
Tg(Mx1-cre)1Cgn/?

(involves: 129 * C57BL/6 * CBA)
absent marginal zone B cells J:90630
Dll1tm3.1Gos/Dll1tm3.1Gos
(Not Specified)
immune system phenotype J:213529
Dll4tm1Frad/Dll4tm1Frad
Foxn1tm3(cre)Nrm/Foxn1+

(B6.Cg-Dll4tm1Frad Foxn1tm3(cre)Nrm)
abnormal T cell differentiation J:143472
abnormal thymus cell ratio J:143472
decreased CD4-positive, alpha-beta T cell number J:143472
decreased CD8-positive, alpha-beta T cell number J:143472
decreased double-positive T cell number J:143472
decreased thymocyte number J:143472
increased immature B cell number J:143472
Dll4tm1Frad/Dll4tm1Frad
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Dll4tm1Frad Tg(Mx1-cre)1Cgn)
immune system phenotype J:143472
Dll4tm1Kaho/Dll4tm1Kaho
Tg(Foxn1-cre)8Ghr/0

(involves: C57BL/6 * DBA/2)
abnormal lymphopoiesis J:143473
absent CD4-positive, alpha-beta T cells J:143473
absent CD8-positive, alpha-beta T cells J:143473
decreased double-positive T cell number J:143473
thymus hypoplasia J:143473
Dmbt1tm1Janm/Dmbt1tm1Janm
(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to induced colitis J:130258
Dmdem1Eno/Y
(involves: C57BL/6J)
myositis J:253191
Dmdem4Eno/Y
(C57BL/6-Dmdem4Eno)
myositis J:285447
Dmdem4Eno/Dmdem4Eno
(C57BL/6-Dmdem4Eno)
myositis J:285447
Dmdmdx/Y
(C57BL/10ScSn-Dmdmdx/J)
increased interferon-gamma secretion J:150572
increased interleukin-2 secretion J:150572
increased interleukin-4 secretion J:150572
increased interleukin-6 secretion J:150572
increased interleukin-12 secretion J:150572
increased tumor necrosis factor secretion J:150572
Dmdmdx/Y
(involves: C57BL/10ScSn)
diaphragmitis J:140282
myositis J:140282
Dmdmdx/Y
Spp1tm1Blh/Spp1tm1Blh

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn)
decreased granulocyte number J:150572
decreased neutrophil cell number J:150572
decreased T cell number J:150572
increased regulatory T cell number J:150572
increased T cell number J:150572
Dmdmdx/Y
Terctm1Rdp/Terctm1Rdp

(involves: 129/Sv * C57BL/6J * C57BL/10ScSn * SJL)
myositis J:167294
Dmdmdx/Y
Tg(DMD*)#Spc/0

(involves: 129P2/OlaHsd * C57BL/10ScSn * DBA/2)
myositis J:280218
Dmdmdx/Y
Utrntm1Jrs/Utrn+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/10ScSn)
diaphragmitis J:140282
myositis J:140282
Dmdmdx/Dmdmdx
(C57BL/10ScSn-Dmdmdx/J)
increased interferon-gamma secretion J:150572
increased interleukin-2 secretion J:150572
increased interleukin-4 secretion J:150572
increased interleukin-6 secretion J:150572
increased interleukin-12 secretion J:150572
increased tumor necrosis factor secretion J:150572
myositis J:226314
Dmdmdx/Dmdmdx
(D2.B10-Dmdmdx/J)
heart inflammation J:226314
myositis J:226314
Dmdmdx/Dmdmdx
Dusp1tm1Brv/Dusp1tm1Brv

(involves: 129S2/SvPas * C57BL/6 * C57BL/10ScSn)
myositis J:162340
Dmdmdx/Dmdmdx
Mmp9tm1Tvu/Mmp9+

(B10.Cg-Mmp9tm1Tvu Dmdmdx)
decreased macrophage cell number J:150030
Dmdmdx/Dmdmdx
Mmp9tm1Tvu/Mmp9tm1Tvu

(B10.Cg-Mmp9tm1Tvu Dmdmdx)
decreased macrophage cell number J:150030
Dmdmdx/Dmdmdx
Prkdcscid/Prkdcscid

(involves: BALB/c * C57BL/10ScSn * C57BL/Ka)
absent CD4-positive, alpha-beta T cells J:125527
absent CD8-positive, alpha-beta T cells J:125527
decreased B cell number J:125527
Dmdmdx/Dmdmdx
Spp1tm1Blh/Spp1tm1Blh

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn)
decreased granulocyte number J:150572
decreased neutrophil cell number J:150572
decreased T cell number J:150572
increased regulatory T cell number J:150572
increased T cell number J:150572
Dmdtm1.1Know/Dmdtm1.1Know
(involves: C3H)
decreased susceptibility to Picornaviridae infection J:207775
myocarditis J:207775
Dmdtm1Kmf/Y
(involves: C57BL/6)
myositis J:233298
Dmp1tm1Mis/Dmp1tm1Mis
(involves: 129S7/SvEvBrd * C57BL/6)
increased susceptibility to bacterial infection J:241769
Dmp1tm1Mis/Dmp1tm1Mis
(involves: 129S7/SvEvBrd * CD-1)
abnormal bone marrow development J:184352
decreased osteoclast cell number J:184352
Dmtf1tm1Cjs/Dmtf1tm1Cjs
(involves: 129/Sv * C57BL/6)
abnormal T cell physiology J:63444
decreased thymocyte number J:63444
Dmxl2tm1a(EUCOMM)Wtsi/Dmxl2tm1a(EUCOMM)Wtsi
(C57BL/6N-Atm1Brd Dmxl2tm1a(EUCOMM)Wtsi/WtsiH)
blood in lymph vessels J:239583
Dnaaf4b2b811.1Clo/Dnaaf4b2b811.1Clo
(C57BL/6J-Dnaaf4b2b811.1Clo)
abnormal spleen morphology J:205312
Dnaaf4tm1.2Jjlo/Dnaaf4tm1.2Jjlo
(involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J)
abnormal spleen morphology J:205312
Dnaaf5em1Slb/Dnaaf5em1Slb
(C57BL/6-Dnaaf5em1Slb)
sinus inflammation J:342770
Dnaaf5em1Slb/Dnaaf5em2Slb
(C57BL/6-Dnaaf5em1Slb Dnaaf5em2Slb)
sinus inflammation J:342770
Dnaaf9tm1b(EUCOMM)Hmgu/Dnaaf9tm1b(EUCOMM)Hmgu
(C57BL/6N-Dnaaf9tm1b(EUCOMM)Hmgu/Tcp)
increased neutrophil cell number J:211773
Dnah2em1(IMPC)Tcp/Dnah2em1(IMPC)Tcp
(C57BL/6N-Dnah2em1(IMPC)Tcp/Tcp)
abnormal lymph node morphology J:211773
Dnah5b2b2451Clo/Dnah5b2b2451Clo
(C57BL/6J-Dnah5b2b2451Clo)
abnormal spleen morphology J:175213
Dnah5b2b2925Clo/Dnah5b2b2925Clo
(C57BL/6J-Dnah5b2b2925Clo)
absent spleen J:175213
Dnah5hlb612/Dnah5hlb612
(involves: C57BL/6J)
abnormal spleen morphology J:130755
absent spleen J:130755
Dnah5Tg1Htz/Dnah5Tg1Htz
(involves: C57BL/6 * CBA/J)
increased susceptibility to otitis media J:76189
sinus inflammation J:76189
Dnah11b2b1289Clo/Dnah11b2b1289Clo
(C57BL/6J-Dnah11b2b1289Clo)
accessory spleen J:175213
Dnah11b2b1727Clo/Dnah11b2b1727Clo
(C57BL/6J-Dnah11b2b1727Clo)
spleen hypoplasia J:175213
Dnah11b2b1775Clo/Dnah11b2b1775Clo
(C57BL/6J-Dnah11b2b1775Clo)
spleen hypoplasia J:175213
Dnah11iv/Dnah11iv
(SI/Col Tyrp1b Dnah11iv/J)
abnormal spleen morphology J:4058
Dnai1b2b1526Clo/Dnai1b2b1526Clo
(C57BL/6J-Dnai1b2b1526Clo)
spleen hypoplasia J:175213
Dnai1tm1.1Leo/Dnai1tm1.1Leo
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+

(involves: 129 * C57BL/6)
rhinosinusitis J:155730
Dnajc2em1(IMPC)J/Dnajc2+
(C57BL/6NJ-Dnajc2em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Dnajc3m1Btlr/Dnajc3m1Btlr
(C57BL/6J-Dnajc3m1Btlr)
increased CD4-positive, alpha-beta T cell number J:265248
increased CD8-positive, alpha-beta memory T cell number J:265248
increased single-positive T cell number J:265248
increased susceptibility to induced colitis J:265248
increased T cell number J:265248
Dnajc11spc/Dnajc11spc
(B6.Cg-Dnajc11spc)
decreased B cell number J:221543
decreased double-positive T cell number J:221543
decreased leukocyte cell number J:221543
decreased thymus weight J:221543
enlarged thymus medulla J:221543
increased CD4-positive, alpha-beta T cell number J:221543
increased CD8-positive, alpha-beta T cell number J:221543
increased DN1 thymic pro-T cell number J:221543
increased double-negative T cell number J:221543
spleen hypoplasia J:221543
thymus cortex atrophy J:221543
thymus hypoplasia J:221543
Dnajc15Gt(RRN226)Byg/Dnajc15Gt(RRN226)Byg
(B6.129P2-Dnajc15Gt(RRN226)Byg)
abnormal CD8-positive, alpha beta T cell morphology J:204025
immune system phenotype J:204025
Dnajc15tm1b(KOMP)Wtsi/Dnajc15tm1b(KOMP)Wtsi
(C57BL/6N-Dnajc15tm1b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Dnal1tm1.1(KOMP)Vlcg/Dnal1+
(C57BL/6N-Dnal1tm1.1(KOMP)Vlcg/Ucd)
decreased eosinophil cell number J:211773
Dnase1tm1Tmo/Dnase1+
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:62549
glomerulonephritis J:62549
increased anti-nuclear antigen antibody level J:62549
kidney inflammation J:62549
Dnase1tm1Tmo/Dnase1tm1Tmo
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:62549
glomerulonephritis J:62549
increased anti-nuclear antigen antibody level J:62549
increased susceptibility to systemic lupus erythematosus J:62549
kidney inflammation J:62549
Dnase1tm1Tmo/Dnase1tm1Tmo
(involves: 129P2/OlaHsd * CD-1)
decreased susceptibility to systemic lupus erythematosus J:110060
Dnase1tm2092.1Arte/Dnase1tm2092.1Arte
(involves: C57BL/6)
glomerulonephritis J:277126
increased anti-double stranded DNA antibody level J:277126
increased anti-histone antibody level J:277126
increased anti-nuclear antigen antibody level J:277126
increased autoantibody level J:277126
increased susceptibility to systemic lupus erythematosus J:277126
Dnase1l2em1(IMPC)Bay/Dnase1l2em1(IMPC)Bay
(C57BL/6N-Dnase1l2em1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
(C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Dnase1l3em1(IMPC)Mbp/Dnase1l3em1(IMPC)Mbp
(C57BL/6NCrl-Dnase1l3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Dnase2atm1Osa/Dnase2atm1Osa
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal thymus morphology J:81474
small thymus J:81474
thymus hypoplasia J:81474
Dnase2atm1Osa/Dnase2atm1Osa
Ifnar1tm1Agt/Ifnar1tm1Agt

(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6)
abnormal cytokine level J:114982
abnormal macrophage morphology J:114982
abnormal spleen morphology J:238323
enlarged spleen J:238323, J:114982
increased anti-double stranded DNA antibody level J:114982
increased autoantibody level J:238323
increased circulating interleukin-10 level J:238323
increased circulating interleukin-18 level J:114982
increased circulating tumor necrosis factor level J:238323, J:114982
increased spleen red pulp amount J:114982
increased spleen weight J:238323
joint inflammation J:238323, J:114982
rheumatoid arthritis J:238323, J:114982
Dnase2atm1Osa/Dnase2atm2Osa
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA)
abnormal cytokine level J:114982
abnormal macrophage morphology J:114982
increased circulating interleukin-18 level J:114982
increased circulating tumor necrosis factor level J:114982
joint inflammation J:114982
rheumatoid arthritis J:114982
Dnm2tm2.1Ics/Dnm2+
(involves: C57BL/6J)
immune system phenotype J:288372
increased macrophage cell number J:288372
Dnmbpem1(IMPC)Mbp/Dnmbpem1(IMPC)Mbp
(C57BL/6N-Dnmbpem1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Dnmt1tm1(tetO-BCL2)Sjk/Dnmt1+
Tg(IghMyc)22Bri/0
Tg(MMTVtTA)1Mam/0

(involves: 129S4/SvJae * C57BL/6)
enlarged spleen J:93549
Dnmt1tm2Jae/Dnmt1tm2Jae
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S4/SvJae * BALB/c * C57BL/6)
abnormal B cell differentiation J:113645
decreased pro-B cell number J:113645
Dnmt3btm1Enl/Dnmt3btm6Enl
(involves: 129S4/SvJae * C57BL/6)
decreased thymocyte number J:106540
increased thymocyte apoptosis J:106540
small thymus J:106540
Dnmt3btm1Enl/Dnmt3btm7Enl
(involves: 129S4/SvJae * C57BL/6)
decreased double-positive T cell number J:106540
decreased thymocyte number J:106540
increased double-negative T cell number J:106540
increased thymocyte apoptosis J:106540
small thymus J:106540
Dnmt3btm6Enl/Dnmt3btm6Enl
(involves: 129S4/SvJae * C57BL/6)
decreased thymocyte number J:106540
increased thymocyte apoptosis J:106540
small thymus J:106540
Dnmt3btm6Enl/Dnmt3btm7Enl
(involves: 129S4/SvJae * C57BL/6)
decreased thymocyte number J:106540
increased thymocyte apoptosis J:106540
Dnmt3btm7Enl/Dnmt3btm7Enl
(involves: 129S4/SvJae * C57BL/6)
decreased thymocyte number J:106540
increased thymocyte apoptosis J:106540
small thymus J:106540
Dntttm1Fwa/Dntttm1Fwa
(chimera involves: 129S/SvEv)
abnormal immune system morphology J:75921
Dntttm1Gfn/Dntttm1Gfn
Faslpr/Faslpr

(involves: 129S2/SvPas * C57BL/6 * MRL/MpJ)
decreased autoantibody level J:110248
Dntttm1Gfn/Dntttm1Gfn
Polmtm1Crey/Polmtm1Crey

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal immunoglobulin light chain V-J recombination J:113406
immune system phenotype J:113406
Dntttm1Tok/Dntttm1Tok
(involves: 129P2/OlaHsd * C57BL/6)
abnormal lymphocyte cell number J:61801
abnormal T cell morphology J:61801
decreased gamma-delta T cell number J:61801
Dnttip1em1Shmc/Dnttip1em1Shmc
(C57BL/6J-Dnttip1em1Shmc)
immune system phenotype J:291786
Dock1b2b3190Clo/Dock1b2b3190Clo
(C57BL/6J-Dock1b2b3190Clo)
thymus hypoplasia J:175213
Dock2m1Anu/Dock2m1Anu
(C57BL/6JAnu-Dock2m1Anu)
decreased B cell number J:104190
decreased T cell number J:104190
Dock2m1Btlr/Dock2m1Btlr
(involves: C57BL/6J)
abnormal B cell differentiation J:173592
abnormal class switch recombination J:185495
abnormal humoral immune response J:173592
decreased B cell number J:185495
decreased IgG level J:185495
decreased T cell number J:185495
immune system phenotype J:185495
Dock2m1Hsd/Dock2m1Hsd
Irf5tm1Ttg/Irf5tm1Ttg

(B6NHsd.Cg-Irf5tm1Ttg Dock2m1Hsd)
abnormal B cell differentiation J:182658
abnormal response to infection J:182658
absent marginal zone B cells J:182658
decreased follicular B cell number J:182658
decreased interferon-alpha secretion J:182658
decreased plasmacytoid dendritic cell number J:182658
decreased splenocyte number J:182658
increased B cell number J:182658
increased immature B cell number J:182658
increased plasmacytoid dendritic cell number J:182658
Dock2m1Hsd/Dock2m1Hsd
Siaetm1.2Avrk/Siaetm1.2Avrk

(B6NHsd.Cg-Siaetm1.2Avrk Dock2m1Hsd)
abnormal B cell activation J:144035
abnormal immunoglobulin level J:144035
decreased B-1a cell number J:144035
decreased follicular B cell number J:144035
decreased marginal zone B cell number J:231437, J:144035
decreased T cell number J:144035
glomerulonephritis J:144035
increased anti-double stranded DNA antibody level J:144035
increased anti-histone antibody level J:144035
increased anti-single stranded DNA antibody level J:144035
increased B cell proliferation J:144035
increased B-1b cell number J:144035
increased CD4-positive, alpha-beta memory T cell number J:231437
increased IgE level J:144035
increased IgG1 level J:144035
increased IgG2a level J:144035
increased IgG2b level J:144035
increased IgG3 level J:144035
increased IgM level J:144035
spleen hypoplasia J:144035
Dock2m2Anu/Dock2m2Anu
(C57BL/6JAnu-Dock2m2Anu)
abnormal T cell morphology J:104190
decreased mature B cell number J:104190
decreased T cell number J:104190
Dock2m2Btlr/Dock2m2Btlr
(C57BL/6J-Dock2m2Btlr)
abnormal humoral immune response J:173670
decreased B cell number J:173670
decreased CD4-positive, alpha-beta T cell number J:173670
decreased CD8-positive, alpha-beta T cell number J:173670
Dock2m2Btlr/Dock2m2Btlr
(involves: C57BL/6J)
abnormal B cell differentiation J:185495
abnormal class switch recombination J:185495
abnormal humoral immune response J:185495
decreased B cell number J:185495
decreased IgG level J:185495
decreased T cell number J:185495
immune system phenotype J:185495
Dock2m3Anu/Dock2m3Anu
(C57BL/6NCrlAnu-Dock2m3Anu)
abnormal CD4-positive, alpha beta T cell morphology J:104190
abnormal CD8-positive, alpha beta T cell morphology J:104190
decreased CD4-positive, alpha-beta T cell number J:104190
Dock2m3Btlr/Dock2m3Btlr
(C57BL/6J-Dock2m3Btlr)
abnormal CD4-positive T cell differentiation J:191187
abnormal CD8-positive, alpha-beta T cell differentiation J:191187
abnormal humoral immune response J:191187
abnormal immune system physiology J:191187
decreased CD4-positive, alpha-beta T cell number J:191187
decreased CD8-positive, alpha-beta T cell number J:191187
Dock2m4Btlr/Dock2m4Btlr
(C57BL/6J-Dock2m4Btlr)
abnormal B cell differentiation J:221486
abnormal CD4-positive T cell differentiation J:221486
abnormal CD8-positive, alpha-beta T cell differentiation J:221486
Dock2m5Btlr/Dock2+
(C57BL/6J-Dock2m5Btlr)
abnormal CD4-positive T cell differentiation J:225938
abnormal CD8-positive, alpha-beta T cell differentiation J:225938
decreased CD4-positive, alpha-beta T cell number J:225938
decreased single-positive T cell number J:225938
increased CD8-positive, alpha-beta T cell number J:225938
increased single-positive T cell number J:225938
Dock2m5Btlr/Dock2m5Btlr
(C57BL/6J-Dock2m5Btlr)
abnormal B cell differentiation J:225938
abnormal CD4-positive T cell differentiation J:225938
abnormal CD8-positive, alpha-beta T cell differentiation J:225938
decreased CD4-positive, alpha-beta T cell number J:225938
decreased single-positive T cell number J:225938
increased B cell number J:225938
increased CD8-positive, alpha-beta T cell number J:225938
increased single-positive T cell number J:225938
Dock2m6Btlr/Dock2m6Btlr
(C57BL/6J-Dock2m6Btlr)
decreased IgE level J:236689
decreased response to antigen J:236689
Dock2m7Btlr/Dock2+
(C57BL/6J-Dock2m7Btlr)
decreased B cell number J:255181
increased macrophage cell number J:255181
increased neutrophil cell number J:255181
Dock2m7Btlr/Dock2m7Btlr
(C57BL/6J-Dock2m7Btlr)
decreased B cell number J:255181
increased IgE level J:255181
increased macrophage cell number J:255181
increased neutrophil cell number J:255181
increased NK cell number J:255181
Dock2m8Btlr/Dock2m8Btlr
(C57BL/6J-Dock2m8Btlr)
decreased CD4-positive, alpha-beta T cell number J:272402
increased CD8-positive, alpha-beta T cell number J:272402
Dock2M9Btlr/Dock2M9Btlr
(C57BL/6J-Dock2M9Btlr)
increased CD8-positive, alpha-beta T cell number J:272403
Dock2m10Btlr/Dock2m10Btlr
(C57BL/6J-Dock2m10Btlr)
decreased B-1b cell number J:272404
increased NK cell number J:272404
Dock2m11Btlr/Dock2m11Btlr
(C57BL/6J-Dock2m11Btlr)
abnormal B cell differentiation J:272405
abnormal CD4-positive T cell differentiation J:272405
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:272405
decreased B cell number J:272405
decreased CD4-positive, alpha-beta T cell number J:272405
decreased CD8-positive, naive alpha-beta T cell number J:272405
decreased NK cell number J:272405
increased B-1 B cell number J:272405
increased CD8-positive, alpha-beta T cell number J:272405
increased central memory CD4-positive, alpha-beta T cell number J:272405
increased central memory CD8 positive, alpha-beta T cell number J:272405
increased effector memory CD4-positive, alpha-beta T cell number J:272405
Dock2M12Btlr/Dock2M12Btlr
(C57BL/6J-Dock2M12Btlr)
decreased B-1a cell number J:272406
Dock2m13Btlr/Dock2m13Btlr
(C57BL/6J-Dock2m13Btlr)
increased alpha-beta T cell number J:272437
increased CD8-positive, alpha-beta T cell number J:272437
Dock2M14Btlr/Dock2M14Btlr
(C57BL/6J-Dock2M14Btlr)
abnormal lymphocyte morphology J:272438
increased CD8-positive, alpha-beta T cell number J:272438
Dock2m15Btlr/Dock2m15Btlr
(C57BL/6J-Dock2m15Btlr)
decreased B cell number J:274942
decreased CD4-positive, alpha-beta T cell number J:274942
decreased CD8-positive, naive alpha-beta T cell number J:274942
decreased T cell number J:274942
increased B-1 B cell number J:274942
increased CD8-positive, alpha-beta T cell number J:274942
increased central memory CD8 positive, alpha-beta T cell number J:274942
increased NK cell number J:274942
Dock2M16Btlr/Dock2M16Btlr
(C57BL/6J-Dock2M16Btlr)
abnormal CD8-positive, alpha-beta T cell number J:274971
Dock2tm1b(EUCOMM)Wtsi/Dock2tm1b(EUCOMM)Wtsi
(C57BL/6N-Dock2tm1b(EUCOMM)Wtsi/BayMmucd)
increased spleen weight J:211773
Dock2tm1Tsas/Dock2tm1Tsas
(involves: C57BL/6)
abnormal immune system morphology J:71005
abnormal leukocyte migration J:71005
abnormal Peyer's patch morphology J:71005
abnormal spleen morphology J:71005
abnormal spleen white pulp morphology J:71005
decreased marginal zone B cell number J:71005
lymph node hypoplasia J:71005
spleen hypoplasia J:71005
Dock2tm1Tsas/Dock2tm1Tsas
(B6.Cg-Dock2tm1Tsas)
decreased lymphocyte cell number J:130919
decreased mature B cell number J:130919
decreased T cell number J:130919
impaired neutrophil chemotaxis J:113266
Dock2tm1Tsas/Dock2tm1Tsas
Tg(Tcra2B4)1Mmd/?
Tg(Tcrb2B4)1Mmd/?

(involves: C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:84581
abnormal T cell physiology J:84581
decreased double-positive T cell number J:84581
Dock3tm1Dasc/Dock3tm1Dasc
(B6.Cg-Dock3tm1Dasc)
abnormal microglial cell physiology J:144341
Dock7mnlt/Dock7mnlt
(C57BL/6J-Dock7mnlt)
immune system phenotype J:146458
Dock8cpm/Dock8cpm
(C57BL/6JSfdAnu-Dock8cpm)
abnormal humoral immune response J:155516
decreased marginal zone B cell number J:155516
decreased spleen germinal center size J:155516
decreased T cell number J:155516
Dock8cpm/Dock8pri
(C57BL/6J-Dock8cpm/Dock8pri)
decreased marginal zone B cell number J:155516
decreased T cell number J:155516
Dock8m1Anu/Dock8m1Anu
(C57BL/6NCrlAnu-Dock8m1Anu)
decreased activated T cell number J:104190
decreased IgM level J:104190
decreased T cell number J:104190
Dock8m1Btlr/Dock8m1Btlr
(C57BL/6J-Dock8m1Btlr)
decreased IgG level J:234247
impaired humoral immune response J:234247
Dock8m2Anu/Dock8m2Anu
(C57BL/6NCrlAnu-Dock8m2Anu)
absent marginal zone B cells J:104190
decreased activated T cell number J:104190
decreased IgM level J:104190
decreased T cell number J:104190
Dock8M2Btlr/Dock8M2Btlr
(C57BL/6J-Dock8M2Btlr)
decreased CD8-positive, alpha-beta T cell number J:272530
Dock8M3Btlr/Dock8M3Btlr
(C57BL/6J-Dock8M3Btlr)
decreased IgG level J:272531
impaired humoral immune response J:272531
Dock8m4Btlr/Dock8m4Btlr
(C57BL/6J-Dock8m4Btlr)
abnormal B cell differentiation J:274856
abnormal CD4-positive T cell differentiation J:274856
abnormal CD8-positive, alpha-beta T cell differentiation J:274856
abnormal T cell differentiation J:274856
decreased B-1 B cell number J:274856
decreased CD4-positive, alpha-beta T cell number J:274856
decreased CD8-positive, alpha-beta T cell number J:274856
decreased CD8-positive, naive alpha-beta T cell number J:274856
decreased T cell number J:274856
increased CD4-positive, alpha-beta T cell number J:274856
increased central memory CD4-positive, alpha-beta T cell number J:274856
increased central memory CD8 positive, alpha-beta T cell number J:274856
increased effector memory CD4-positive, alpha-beta T cell number J:274856
increased effector memory CD8-positive, alpha-beta T cell number J:274856
Dock8pri/Dock8pri
(C57BL/6JAnu-Dock8pri)
abnormal humoral immune response J:155516
decreased B-1 B cell number J:155516
decreased germinal center B cell number J:155516
decreased marginal zone B cell number J:155516
decreased spleen germinal center size J:155516
decreased T cell number J:155516
Dock8pri/Dock8pri
(involves: C57BL/6JAnu)
abnormal cellular extravasation J:238772
decreased susceptibility to experimental autoimmune encephalomyelitis J:238772
Dock8tm1Ysfk/Dock8tm1Ysfk
(B6.Cg-Dock8tm1Ysfk)
abnormal dendritic cell physiology J:185165
decreased CD4-positive, alpha-beta T cell number J:185165
decreased CD8-positive, alpha-beta T cell number J:185165
decreased follicular dendritic cell number J:185165
decreased IgG level J:185165
decreased marginal zone B cell number J:185165
decreased T cell proliferation J:185165
Dock9tm1Thar/Dock9tm1Thar
(involves: C57BL/6)
immune system phenotype J:300632
Dock10tm1a(EUCOMM)Hmgu/Dock10tm1a(EUCOMM)Hmgu
(C57BL/6N-Dock10tm1a(EUCOMM)Hmgu/Ieg)
abnormal B cell physiology J:236911
abnormal follicular B cell physiology J:236911
abnormal spleen marginal zone morphology J:238172
abnormal thymus cell ratio J:238172
arrested B cell differentiation J:236911
decreased B cell number J:236911
decreased follicular B cell number J:236911
decreased marginal zone B cell number J:236911
immune system phenotype J:238172
increased single-positive T cell number J:236911
increased T cell number J:236911
Dock10tm1Thar/Dock10tm1Thar
(involves: C57BL/6)
abnormal microglial cell chemotaxis J:300632
decreased B cell number J:300632
decreased susceptibility to experimental autoimmune encephalomyelitis J:300632
impaired macrophage chemotaxis J:300632
Dock11tm1.1Mmar/Dock11tm1.1Mmar
(Not Specified)
abnormal metallophilic macrophage morphology J:238172
abnormal spleen marginal zone morphology J:238172
abnormal thymus cell ratio J:238172
decreased marginal zone B cell number J:238172
immune system phenotype J:238172
Dock11tm1Thar/Dock11tm1Thar
(involves: C57BL/6)
immune system phenotype J:300632
impaired macrophage chemotaxis J:300632
Dohhtm1.2Sbal/Dohh+
(B6.129(Cg)-Dohhtm1.2Sbal)
abnormal spleen morphology J:214321
Dok1tm1Ppp/Dok1tm1Ppp
(129S1/Sv-Dok1tm1Ppp)
abnormal T cell proliferation J:95640
Dok1tm1Ppp/Dok1tm1Ppp
Dok2tm1Ppp/Dok2tm1Ppp

(129S1/Sv-Dok1tm1Ppp Dok2tm1Ppp)
abnormal leukocyte physiology J:95334
enlarged spleen J:95334
increased leukocyte cell number J:95334
increased monocyte cell number J:95334
increased neutrophil cell number J:95334
Dok1tm1Ppp/Dok1tm1Ppp
Dok2tm1Ppp/Dok2tm1Ppp
Dok3tm1Ppp/Dok3tm1Ppp

(129S1/Sv-Dok1tm1Ppp Dok2tm1Ppp Dok3tm1Ppp)
increased leukocyte cell number J:158011
Dok1tm1Yyam/Dok1tm1Yyam
(involves: 129S4/SvJae * C57BL/6)
decreased IgM level J:95641
increased B cell proliferation J:95641
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam

(B6.129-Dok1tm1Yyam Dok2tm1Yyam)
abnormal leukocyte physiology J:95335
abnormal myelopoiesis J:95335
enlarged spleen J:95335
increased leukocyte cell number J:95335
increased monocyte cell number J:95335
increased neutrophil cell number J:95335
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal macrophage physiology J:163407
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
Dok3tm1Brs/Dok3tm1Brs

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal macrophage physiology J:163407
increased macrophage cell number J:163407
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
Tg(Tec-BCR/ABL1)5Hhi/0

(involves: C57BL/6)
enlarged lymph nodes J:95335
enlarged thymus J:95335
Dok1tm1Yyam/Dok1tm1Yyam
Tg(Tec-BCR/ABL1)5Hhi/0

(involves: C57BL/6)
enlarged lymph nodes J:95335
enlarged thymus J:95335
Dok2tm1Ppp/Dok2tm1Ppp
(129S1/Sv-Dok2tm1Ppp)
abnormal granulocyte physiology J:95334
Dok2tm1Yyam/Dok2tm1Yyam
Tg(Tec-BCR/ABL1)5Hhi/0

(involves: C57BL/6)
enlarged lymph nodes J:95335
enlarged thymus J:95335
Dok3tm1Brs/Dok3tm1Brs
(involves: C57BL/6)
increased macrophage cell number J:163407
Dok3tm1Kplm/Dok3tm1Kplm
(involves: 129P2/OlaHsd)
abnormal B cell physiology J:280795
enhanced humoral immune response J:280795
increased B cell proliferation J:280795
increased IgG3 level J:280795
increased IgM level J:280795
Dok7tm1.1(KOMP)Vlcg/Dok7+
(C57BL/6N-Dok7tm1.1(KOMP)Vlcg/Ucd)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Dop1btm1a(EUCOMM)Wtsi/Dop1btm1a(EUCOMM)Wtsi
(C57BL/6N-Dop1btm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Dot1ltm1.1Saam/Dot1ltm1.1Saam
Tg(VAV1-cre)1Graf/0

(involves: 129S1/Sv * C57BL/6)
abnormal leukopoiesis J:193161
decreased lymphocyte cell number J:193161
decreased neutrophil cell number J:193161
Dp(11Cops3-Rnf112)1Jrl/0
(involves: 129S7/SvEvBrd * C57BL/6)
decreased spleen weight J:83302
Dp(16Cbr1-Fam3b)1Rhr/0
Gata1tm8.2Sho/Y

(involves: 129S1/Sv * 129S6/SvEvTac)
enlarged spleen J:184564
increased monocyte cell number J:184564
Dp(17Nfkbil1-Or2h1)1Cogr/0
(involves: 129S6/SvEvTac * C57BL/6J)
immune system phenotype J:190754
Dpcd/PollGt(OST280355)Lex/Dpcd/PollGt(OST280355)Lex
(involves: 129S5/SvEvBrd * C57BL/6Brd)
increased susceptibility to otitis media J:185566
Dph6tm1a(KOMP)Wtsi/Dph6tm1a(KOMP)Wtsi
(C57BL/6N-Dph6tm1a(KOMP)Wtsi/Wtsi)
decreased CD8-positive, alpha-beta T cell number J:211773
decreased CD8-positive, naive alpha-beta T cell number J:211773
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased Ly6C-positive mature NK cell number J:211773
decreased mature B cell number J:211773
decreased NK T cell number J:211773
decreased T-helper cell number J:211773
increased CD4-positive, alpha-beta memory T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased CD5-positive gamma-delta T cell number J:211773
increased CD11b-low dendritic cell number J:211773
increased dendritic cell number J:211773
increased effector memory T-helper cell number J:211773
increased gamma-delta T cell number J:211773
increased granulocyte number J:211773
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased KLRG1-positive T-helper cell number J:211773
increased marginal zone B cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased memory-marker CD4-negative NK T cell number J:211773
increased memory-marker gamma-delta T cell number J:211773
increased monocyte cell number J:211773
increased plasma cell number J:211773
increased plasmacytoid dendritic cell number J:211773
Dpp3tm1d(EUCOMM)Hmgu/Dpp3tm1d(EUCOMM)Hmgu
(involves: BALB/c * C57BL/6 * C57BL/6J * C57BL/6N * SJL)
abnormal interferon-gamma secretion J:294242
increased interleukin-1 beta secretion J:294242
increased interleukin-6 secretion J:294242
increased interleukin-10 secretion J:294242
increased osteoclast cell number J:294242
increased tumor necrosis factor secretion J:294242
Dpp4em1Rba/Dpp4+
(C57BL/6J-Dpp4em1Rba)
decreased susceptibility to Coronaviridae infection induced morbidity/mortality J:279834
increased susceptibility to Coronaviridae infection J:279834
lung inflammation J:279834
Dpp4em1Rba/Dpp4em1Rba
(C57BL/6J-Dpp4em1Rba)
decreased lymphocyte cell number J:279723
increased monocyte cell number J:279723
increased neutrophil cell number J:279723
increased susceptibility to Coronaviridae infection J:279723, J:279834
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:279834
lung inflammation J:279834
Dpp4em3Gpt/Dpp4em3Gpt
(C57BL/6JGpt-Dpp4em3Gpt)
immune system phenotype J:324112
Dpp4tm1(DPP4)Vlcg/?
(involves: 129S6/SvEvTac * C57BL/6NTac)
increased susceptibility to Coronaviridae infection J:223728
interstitial pneumonia J:223728
lung inflammation J:223728
Dpp4tm1(DPP4)Vlcg/?
(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac)
increased CD4-positive, alpha-beta T cell number J:238079
increased CD8-positive, alpha-beta T cell number J:238079
increased macrophage cell number J:238079
increased neutrophil cell number J:238079
increased susceptibility to Coronaviridae infection J:238079
lung inflammation J:238079
pleuritis J:238079
Dpp4tm1.1(DPP4)Pbmj/Dpp4tm1.1(DPP4)Pbmj
(involves: C57BL/6 * C57BL/6NTac)
increased susceptibility to Coronaviridae infection J:242025
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:242025
lung inflammation J:242025
Dpp4tm1b(EUCOMM)Wtsi/Dpp4tm1b(EUCOMM)Wtsi
(C57BL/6N-Dpp4tm1b(EUCOMM)Wtsi/Ics)
decreased lymphocyte cell number J:211773
Dppa1tm1b(KOMP)Wtsi/Dppa1+
(C57BL/6N-Dppa1tm1b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Drc1b2b1654Clo/Drc1b2b1654Clo
(C57BL/6J-Drc1b2b1654Clo)
absent spleen J:175213
Drd1tm1Jcd/Drd1tm1Jcd
Drd2tm1Ebo/Drd2+

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6)
small intestinal inflammation J:91781
Drd1tm2Jcd/Drd1+
Tg(Camk2a-cre)2Gsc/0

(involves: 129S4/SvJae * FVB/N)
abnormal microglial cell physiology J:120070
Drd2tm1Low/Drd2tm1Low
(B6.129S2-Drd2tm1Low/J)
decreased spleen weight J:106832
increased interleukin-1 beta secretion J:194407
microgliosis J:194407
Drd3em1(IMPC)Mbp/Drd3em1(IMPC)Mbp
(C57BL/6N-Drd3em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Drgxem1(IMPC)Mbp/Drgx+
(C57BL/6N-Drgxem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Droshatm1Litt/Droshatm1.1Litt
Foxp3tm4(YFP/icre)Ayr/Y

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
abnormal interferon-gamma secretion J:138683
abnormal interleukin-4 secretion J:138683
abnormal T cell activation J:138683
blood vessel inflammation J:138683
enlarged lymph nodes J:138683
enlarged spleen J:138683
increased CD8-positive, alpha-beta T cell number J:138683
increased leukocyte cell number J:138683
liver inflammation J:138683
lung inflammation J:138683
Droshatm1Litt/Droshatm1.1Litt
Foxp3tm4(YFP/icre)Ayr/Foxp3tm4(YFP/icre)Ayr

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
abnormal interferon-gamma secretion J:138683
abnormal interleukin-4 secretion J:138683
abnormal regulatory T cell morphology J:138683
abnormal T cell activation J:138683
blood vessel inflammation J:138683
enlarged lymph nodes J:138683
enlarged spleen J:138683
increased CD8-positive, alpha-beta T cell number J:138683
increased leukocyte cell number J:138683
liver inflammation J:138683
lung inflammation J:138683
Droshatm1Litt/Droshatm1.1Litt
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+

(involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal interferon-gamma secretion J:138683
Droshatm1Litt/Droshatm1.1Litt
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N)
abnormal immune system physiology J:138683
decreased CD8-positive, alpha-beta T cell number J:138683
decreased double-positive T cell number J:138683
decreased lymphocyte cell number J:138683
decreased regulatory T cell number J:138683
decreased thymocyte number J:138683
immune system phenotype J:138683
increased activated T cell number J:138683
increased gamma-delta T cell number J:138683
increased granulocyte number J:138683
intestinal inflammation J:138683
liver inflammation J:138683
lung inflammation J:138683
Dsc1tm1Dga/Dsc1tm1Dga
(involves: C57BL/6J)
dermatitis J:73102
Dsc2tm1.1Leu/Dsc2tm1.1Leu
Tg(Vil1-cre)20Syr/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
immune system phenotype J:302333
Dsg2m1Btlr/Dsg2m1Btlr
(C57BL/6J-Dsg2m1Btlr)
increased susceptibility to induced colitis J:271975
Dsg2m2Btlr/Dsg2m2Btlr
(C57BL/6J-Dsg2m2Btlr)
increased susceptibility to induced colitis J:271976
Dsg2m3Btlr/Dsg2m3Btlr
(C57BL/6J-Dsg2m3Btlr)
increased susceptibility to induced colitis J:271977
Dsg2tm1d(EUCOMM)Wtsi/Dsg2tm1d(EUCOMM)Wtsi
(involves: C57BL/6J * C57BL/6N)
heart inflammation J:235770
Dsg2tm3.1Leu/Dsg2tm3.1Leu
Tg(Vil1-cre)20Syr/0

(involves: 129S7/SvEvBrd * C57BL/6 * DBA/2)
increased susceptibility to colitis induced morbidity/mortality J:302333
increased susceptibility to induced colitis J:302333
Dsg3bal/Dsg3bal
(C57BL/6J-Dsg3bal/J)
cutaneous mastocytosis J:18223
increased IgE level J:18223
Dsg3sqk/Dsg3sqk
(C57BL/6-Dsg3sqk)
conjunctivitis J:219200
decreased B cell number J:219200
decreased double-positive T cell number J:219200
decreased immature B cell number J:219200
decreased lymphocyte cell number J:219200
decreased pre-B cell number J:219200
decreased single-positive T cell number J:219200
decreased transitional stage B cell number J:219200
increased neutrophil cell number J:219200
increased susceptibility to infection J:219200
Dsg3tm1Stan/Dsg3tm1Stan
(involves: 129X1/SvJ * C57BL/6J)
conjunctivitis J:40804
Dsg4hage/Dsg4hage
Faslpr/Faslpr
X/Yaa

(EOD-Dsg4hage)
abnormal effector T cell morphology J:140028
abnormal mast cell morphology J:140028
Dsg4lah-J/Dsg4lah-J
(involves: DBA/1LacJ)
abnormal peripheral lymph node morphology J:83117
dermatitis J:83117
increased IgE level J:83117
Dsg4lah/Dsg4lah
(LAH/Pas)
dermatitis J:33849
Dspem1(IMPC)Mbp/Dsp+
(C57BL/6N-Dspem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Dspptm1Kul/Dspptm1Kul
(B6;129-Dspptm1Kul/Mmnc)
periodontium inflammation J:241990
Dssc1C3H/HeJ/Dssc1C57BL/6J
(involves: C3H/HeJ * C57BL/6J)
colitis J:52852
Dssc1C57BL/6J/Dssc1C57BL/6J
(involves: C3H/HeJ * C57BL/6J)
colitis J:52852
Dssc2C3H/HeJ/Dssc2C3H/HeJ
(involves: C3H/HeJ * C57BL/6J)
colitis J:52852
Dssc2C3H/HeJ/Dssc2C57BL/6J
(involves: C3H/HeJ * C57BL/6J)
colitis J:52852
DstTg4/DstTg4
(involves: C57BL/6 * CD-1)
conjunctivitis J:209161
Dstncorn1/Dstncorn1
(A.BY-H2bc H2-T18f/SnJ)
abnormal lymphangiogenesis J:98465
immune system phenotype J:98465
Dstncorn1/Dstncorn1
(A.BY-H2bc H2-T18f/SnJ-Dstncorn1/J)
immune system phenotype J:139239
Dtnbp1sdy-Btlr/Dtnbp1sdy-Btlr
(C57BL/6J-Dtnbp1sdy-Btlr)
impaired natural killer cell mediated cytotoxicity J:133620
increased susceptibility to Herpesvirales infection J:133620
Dtnbp1tm1b(EUCOMM)Hmgu/Dtnbp1tm1b(EUCOMM)Hmgu
(C57BL/6N-Dtnbp1tm1b(EUCOMM)Hmgu/Tcp)
decreased lymphocyte cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Dtx1tm1.1Mzl/Dtx1tm1.1Mzl
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal thymocyte activation J:151605
increased anti-double stranded DNA antibody level J:151605
increased anti-histone antibody level J:151605
increased autoantibody level J:151605
increased interleukin-2 secretion J:151605
increased T cell proliferation J:151605
Dtx1tm1.2Mzl/Dtx1tm1.2Mzl
(B6.129-Dtx1tm1.2Mzl)
abnormal lymphocyte morphology J:151605
abnormal lymphocyte physiology J:151605
abnormal regulatory T cell physiology J:151605
abnormal T cell anergy J:151605
abnormal thymocyte activation J:151605
decreased marginal zone B cell number J:151605
decreased thymocyte apoptosis J:151605
glomerulonephritis J:151605
increased anti-double stranded DNA antibody level J:151605
increased anti-histone antibody level J:151605
increased B cell proliferation J:151605
increased interferon-gamma secretion J:151605
increased interleukin-2 secretion J:151605
increased interleukin-4 secretion J:151605
increased T cell proliferation J:151605
liver inflammation J:151605
lung inflammation J:151605
spleen hyperplasia J:151605
Dtx1tm1Mjb/Dtx1tm1Mjb
(either: B6.129S6-Dtx1tm1Mjb or (involves: 129S6/SvEvTac * C57BL/6))
immune system phenotype J:114658
Dtx1tm1Mjb/Dtx1tm1Mjb
Dtx2tm1Mjb/Dtx2tm1Mjb

(involves: 129S6/SvEvTac * C57BL/6)
immune system phenotype J:114658
Dtx2tm1Mjb/Dtx2tm1Mjb
(involves: 129S6/SvEvTac)
immune system phenotype J:114658
Dtx4em1(IMPC)Ccpcz/Dtx4+
(C57BL/6N-Dtx4em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Ducm1129X1/SvJ/Ducm1129X1/SvJ
(involves: 129X1/SvJ * C57BL/6J)
abnormal professional antigen presenting cell physiology J:86617
Ducm1129X1/SvJ/Ducm1C57BL/6J
(involves: 129X1/SvJ * C57BL/6J)
abnormal professional antigen presenting cell physiology J:86617
Duox2em1(IMPC)Mbp/Duox2em1(IMPC)Mbp
(C57BL/6N-Duox2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
small spleen J:211773
Duoxa2tm1b(KOMP)Wtsi/Duoxa2tm1b(KOMP)Wtsi
(C57BL/6N-Duoxa2tm1b(KOMP)Wtsi/Wtsi)
decreased B cell number J:211773
decreased B-2 B cell number J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased CD11b-high dendritic cell number J:211773
decreased effector memory T-helper cell number J:211773
decreased follicular B cell number J:211773
decreased immature B cell number J:211773
decreased KLRG1-positive NK cell number J:211773
decreased leukocyte cell number J:211773
decreased Ly6C low monocyte number J:211773
decreased mature B cell number J:211773
decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
decreased memory-marker gamma-delta T cell number J:211773
decreased NK cell number J:211773
decreased transitional stage T1 B cell number J:211773
increased alpha-beta T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased neutrophil cell number J:211773
increased plasmacytoid dendritic cell number J:211773
increased T cell number J:211773
increased T-helper cell number J:211773
Dusp1tm1Brv/Dusp1tm1Brv
(involves: 129S2/SvPas)
abnormal cytokine secretion J:118832
lung inflammation J:118832
Dusp1tm1Brv/Dusp1tm1Brv
(involves: 129S2/SvPas * C57BL/6)
increased circulating interleukin-6 level J:118833
increased circulating interleukin-10 level J:118833
increased circulating tumor necrosis factor level J:118833
increased interleukin-6 secretion J:118833
increased susceptibility to endotoxin shock J:118833
increased tumor necrosis factor secretion J:118833
Dusp1tm1Brv/Dusp1tm1Brv
(involves: 129S2/SvPas * various)
immune system phenotype J:125919
increased mast cell degranulation J:125919
increased susceptibility to type I hypersensitivity reaction J:125919
Dusp1tm1Brv/Dusp1tm1Brv
(C3.129S2-Dusp1tm1Brv)
abnormal chemokine secretion J:164929
increased granulocyte number J:164929
increased interleukin-1 beta secretion J:164929
increased interleukin-6 secretion J:164929
increased susceptibility to bacterial infection J:164929
lung inflammation J:164929
Dusp1tm1Lex/Dusp1tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal chemokine level J:126383
abnormal innate immunity J:126383
abnormal interleukin level J:126383
increased circulating interferon-gamma level J:126383
increased circulating interleukin-6 level J:126383
increased circulating interleukin-10 level J:126383
increased circulating tumor necrosis factor level J:126383
increased susceptibility to endotoxin shock J:126383
increased susceptibility to induced arthritis J:126383
Dusp2tm1Cmac/Dusp2tm1Cmac
(B6.Cg-Dusp2tm1Cmac)
abnormal cytokine secretion J:112609
abnormal macrophage activation involved in immune response J:112609
abnormal mast cell physiology J:112609
decreased susceptibility to induced arthritis J:112609
Dusp4Gt(XG164)Byg/Dusp4Gt(XG164)Byg
(B6.129P2-Dusp4Gt(XG164)Byg)
immune system phenotype J:180366
increased CD4-positive, alpha-beta T cell number J:180366
increased interleukin-10 secretion J:180366
increased T cell proliferation J:180366
Dusp4tm1Jmol/Dusp4tm1Jmol
(involves: 129)
decreased B cell apoptosis J:140567
Dusp4tm1Plev/Dusp4tm1Plev
(involves: 129/Sv * C57BL/6)
abnormal macrophage physiology J:170774
decreased IgG2a level J:170774
decreased interferon-gamma secretion J:170774
decreased interleukin-10 secretion J:170774
increased IgG1 level J:170774
increased interleukin-4 secretion J:170774
increased interleukin-6 secretion J:170774
increased interleukin-12 secretion J:170774
increased interleukin-13 secretion J:170774
increased susceptibility to parasitic infection J:170774
increased tumor necrosis factor secretion J:170774
Dusp5tm1.1Achn/Dusp5tm1.1Achn
(involves: C57BL/6NCrl)
abnormal susceptibility to parasitic infection J:218203
immune system phenotype J:218203
increased T cell proliferation J:218203
increased thymocyte number J:218203
Dusp5tm1.1Achn/Dusp5tm1.1Achn
Rag2tm1.1Cgn/Rag2tm1.1Cgn

(involves: C57BL/6NCrl)
abnormal eosinophil physiology J:218203
abnormal susceptibility to parasitic infection J:218203
increased eosinophil cell number J:218203
Dusp5tm1a(KOMP)Wtsi/Dusp5tm1a(KOMP)Wtsi
(C57BL/6-Dusp5tm1a(KOMP)Wtsi)
abnormal CD8-positive, alpha beta T cell morphology J:240637
abnormal T cell physiology J:240637
increased effector memory CD8-positive, alpha-beta T cell number J:240637
increased T cell apoptosis J:240637
increased T cell proliferation J:240637
Dusp5tm1d(KOMP)Wtsi/Dusp5tm1d(KOMP)Wtsi
(B6(Cg)-Dusp5tm1d(KOMP)Wtsi)
increased T cell apoptosis J:240637
Dusp6tm1Jmol/Dusp6tm1Jmol
(involves: 129 * C57BL/6)
increased spleen weight J:142966
Dusp8em1(IMPC)Mbp/Dusp8em1(IMPC)Mbp
(C57BL/6N-Dusp8em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Dusp10tm1Flv/Dusp10tm1Flv
(involves: 129S6/SvEvTac)
abnormal adaptive immunity J:92104
abnormal cytokine secretion J:92104
abnormal interleukin secretion J:92104
decreased susceptibility to experimental autoimmune encephalomyelitis J:92104
decreased T cell proliferation J:92104
increased activated T cell number J:92104
increased interferon-gamma secretion J:92104
increased susceptibility to type I hypersensitivity reaction J:92104
increased tumor necrosis factor secretion J:92104
Dusp11Gt(BB0198)Wtsi/Dusp11Gt(BB0198)Wtsi
(B6.129P2-Dusp11Gt(BB0198)Wtsi)
abnormal macrophage activation involved in immune response J:301503
immune system phenotype J:301503
increased circulating interleukin-1 beta level J:301503
increased circulating interleukin-6 level J:301503
increased circulating tumor necrosis factor level J:301503
increased macrophage cytokine production J:301503
increased susceptibility to endotoxin shock J:301503
Dusp14Gt(OST210117)Lex/Dusp14Gt(OST210117)Lex
(B6.129S5-Dusp14Gt(OST210117)Lex)
abnormal cytokine secretion J:209403
abnormal humoral immune response J:209403
abnormal T cell activation J:209403
immune system phenotype J:209403
increased susceptibility to experimental autoimmune encephalomyelitis J:209403
increased T cell proliferation J:209403
increased T-helper 1 cell number J:209403
increased T-helper 17 cell number J:209403
Dusp16em1(IMPC)Tcp/Dusp16em1(IMPC)Tcp
(C57BL/6NCrl-Dusp16em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Dusp22tm1Tht/Dusp22tm1Tht
(B6.129S7-Dusp22tm1Tht)
abnormal B cell activation J:213253
abnormal cytokine level J:213253
abnormal T cell activation J:213253
decreased B cell proliferation J:213253
decreased IgG3 level J:213253
decreased IgM level J:213253
decreased immunoglobulin level J:213253
enlarged spleen J:213253
increased circulating interferon-gamma level J:213253
increased circulating interleukin-6 level J:213253
increased circulating interleukin-17 level J:213253
increased circulating tumor necrosis factor level J:213253
increased inflammatory response J:213253
increased interferon-gamma secretion J:213253
increased interleukin-2 secretion J:213253
increased interleukin-4 secretion J:213253
increased interleukin-17 secretion J:213253
increased spleen white pulp amount J:213253
increased susceptibility to autoimmune disorder J:213253
increased susceptibility to experimental autoimmune encephalomyelitis J:213253
increased T cell proliferation J:213253
kidney inflammation J:213253
liver inflammation J:213253
lung inflammation J:213253
Dvl3b2b2866Clo/Dvl3b2b2866Clo
(C57BL/6J-Dvl3b2b2866Clo)
thymus hypoplasia J:175213
Dync1li1em1(IMPC)Tcp/Dync1li1+
(C57BL/6NCrl-Dync1li1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Dyrk1atm1Jdc/Dyrk1atm1Jdc
Tg(Mx1-cre)1Cgn/0

(involves: 129/Sv * C57BL/6J * C57BL/6NTac * CBA/J)
decreased B cell number J:223138
decreased double-positive T cell number J:223138
decreased immature B cell number J:223138
decreased mature B cell number J:223138
decreased pre-B cell number J:223138
decreased thymocyte number J:223138
increased T cell apoptosis J:223138
Dyrk1btm1b(EUCOMM)Wtsi/Dyrk1b+
(C57BL/6N-Dyrk1btm1b(EUCOMM)Wtsi/Ics)
decreased large unstained cell number J:211773
decreased lymphocyte cell number J:211773
Dyrk2em1(IMPC)Ics/Dyrk2+
(C57BL/6N-Dyrk2em1(IMPC)Ics/Ics)
decreased large unstained cell number J:211773
Dysfim/Dysf+
Large1myd/Large1myd

(involves: C57BL/6 * SJL/J)
myositis J:221523
Dysfim/Dysfim
Fktntm1Ttd/Fktntm2(FCMD)Ttd

(involves: 129S7/SvEvBrd * C57BL/6 * SJL/J)
myositis J:221523
Dysfim/Dysfim
Large1myd/Large1myd

(involves: C57BL/6 * SJL/J)
myositis J:221523
Dysftm1Kcam/Dysftm1Kcam
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
myositis J:171870
Dytnem1(IMPC)J/Dytnem1(IMPC)J
(C57BL/6NJ-Dytnem1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
E2f1Tg(Wnt1-cre)2Sor/E2f1+
Snrpbem1Lajm/Snrpb+

(involves: C3H * C57BL/6 * C57BL/6J * CD1)
athymia J:326544
E2f1tm1Meg/E2f1tm1Meg
(either: (involves: 129/Sv * 129S4/SvJae) or (involves: 129/Sv * 129S4/SvJae * C57BL/6))
abnormal double-positive T cell morphology J:33100
enlarged thymus J:33100
increased CD4-positive, alpha-beta T cell number J:33100
increased CD8-positive, alpha-beta T cell number J:33100
increased thymocyte number J:33100
increased thymus weight J:33100
E2f1tm1Meg/E2f1tm1Meg
(NOD.Cg-E2f1tm1Meg)
abnormal CD4-positive, alpha beta T cell morphology J:93708
abnormal CD8-positive, alpha beta T cell morphology J:93708
abnormal double-positive T cell morphology J:93708
decreased double-positive T cell number J:93708
decreased regulatory T cell number J:93708
enlarged thymus J:93708
increased interferon-gamma secretion J:93708
increased interleukin-4 secretion J:93708
increased susceptibility to autoimmune diabetes J:93708
increased T cell number J:93708
increased thymocyte number J:93708
insulitis J:93708
salivary gland inflammation J:93708
E2f1tm1Meg/E2f1tm1Meg
(involves: 129S4/SvJae * C57BL/6)
decreased T cell proliferation J:76318
E2f2tm1Zubi/E2f2tm1Zubi
(involves: 129S1/Sv * C57BL/6)
abnormal immune system morphology J:76318
abnormal immune system physiology J:76318
abnormal spleen white pulp morphology J:76318
abnormal T cell differentiation J:76318
abnormal T cell subpopulation ratio J:76318
enlarged spleen J:76318
glomerulonephritis J:76318
increased anti-double stranded DNA antibody level J:76318
increased inflammatory response J:76318
increased memory T cell number J:76318
increased spleen weight J:76318
increased susceptibility to autoimmune disorder J:76318
increased T cell proliferation J:76318
liver inflammation J:76318
lung inflammation J:76318
E2f2tm1Zubi/E2f2tm1Zubi
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129S1/Sv * C57BL/6 * C57BL/6J * DBA/2J)
abnormal immune system morphology J:76318
abnormal immune system physiology J:76318
enlarged spleen J:76318
increased CD8-positive, alpha-beta T cell number J:76318
increased inflammatory response J:76318
increased susceptibility to autoimmune disorder J:76318
increased T cell proliferation J:76318
thymus hypoplasia J:76318
E2f3tm1Lees/E2f3tm1Lees
(involves: 129S2/SvPas * C57BL/6)
lung inflammation J:75765
E2f4tm1Jrn/E2f4tm1Jrn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal granulocyte morphology J:64192
decreased double-positive T cell number J:64192
decreased granulocyte number J:64192
decreased thymocyte number J:64192
increased double-negative T cell number J:64192
increased NK cell number J:64192
thymus hypoplasia J:64192
E2f4tm1Lees/E2f4tm1Lees
(involves: 129S2/SvPas * C57BL/6)
increased susceptibility to bacterial infection J:64193
increased susceptibility to otitis media J:64193
rhinitis J:64193
E2f4tm1Lees/E2f4tm1Lees
Rb1tm1Tyj/Rb1+

(involves: 129S2/SvPas * C57BL/6)
increased susceptibility to infection J:81082
Eae1A/J/Eae1A/J
(involves: A/J * C57BL/10SnJ)
increased susceptibility to experimental autoimmune encephalomyelitis J:30574
Eae1PL/J/Eae1PL/J
(involves: C57BL/10SnJ * PL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:30574
Eae2B10.RIII/Eae2RIIIS/J
(involves: B10.RIII * RIIIS/J)
arthritis J:95848
Eae2RIIIS/J/Eae2RIIIS/J
(involves: B10.RIII * RIIIS/J)
decreased susceptibility to induced arthritis J:95848
Eae2bC57BL/10SnSg/Eae2bC57BL/10SnSg
(involves: B10.RIII * RIIIS/J)
CNS inflammation J:96204
Eae4ABH/?
(involves: ABH * NOD)
increased susceptibility to experimental autoimmune encephalomyelitis J:29171
Eae5B10.S/DvTe/Eae5SJL/J
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:49054
Eae5SJL/J/Eae5SJL/J
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:49054
Eae7B10.S/DvTe/Eae7B10.S/DvTe
(involves: B10.S/DvTe * SJL/J)
brain inflammation J:49054
increased susceptibility to experimental autoimmune encephalomyelitis J:49054
Eae7B10.S/DvTe/Eae7SJL/J
(involves: B10.S/DvTe * SJL/J)
brain inflammation J:49054
increased susceptibility to experimental autoimmune encephalomyelitis J:49054
Eae7SJL/J/Eae7SJL/J
(involves: B10.S/DvTe * SJL/J)
brain inflammation J:49054
decreased susceptibility to experimental autoimmune encephalomyelitis J:49054
Eae9B10.S/DvTe/Eae9SJL/J
(involves: B10.S/DvTe * SJL/J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:49054
Eae10SJL/J/Eae10SJL/J
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:49054
Eae11SJL/J/?
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:53193
Eae12SJL/J/Eae12SJL/J
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:53193
Eae13SJL/J/?
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:53193
Eae14C57BL/10/?
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:69083
Eae16SJL/J/?
(involves: B10.S/DvTe * SJL/J)
increased inflammatory response J:67840
Eae17SJL/J/?
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:69083
Eae18NOD/Eae18NOD
(involves: ABH * NOD)
decreased susceptibility to experimental autoimmune encephalomyelitis J:29171
Eae21SJL/J/?
(involves: B10.S/DvTe * SJL/J)
increased inflammatory response J:67840
Eae22SJL/J/?
(involves: B10.S/DvTe * SJL/J)
increased inflammatory response J:67840
Eae23SJL/J/?
(involves: B10.S/DvTe * SJL/J)
increased inflammatory response J:67840
Eae25SJL/J/?
(involves: B10.S/DvTe * SJL/J)
increased inflammatory response J:69083
Eae26B10.RIII/Eae26B10.RIII
(involves: B10.RIII * RIIIS/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:73850
Eae26B10.RIII/Eae26RIIIS/J
(involves: B10.RIII * RIIIS/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:73850
Eae27C57BL/10SnSg/Eae27RIIIS/J
(involves: B10.RIII * RIIIS/J)
CNS inflammation J:96204
Eae27RIIIS/J/Eae27RIIIS/J
(involves: B10.RIII * RIIIS/J)
CNS inflammation J:96204
Eae33C57BL/10SnSg/?
(involves: B10.S * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:99793
Eae34C57BL/10SnSg/?
(involves: B10.S * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:99793
Eae35C57BL/10SnSg/?
(involves: B10.S * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:99793
Eae36SJL/J/?
(involves: B10.S * SJL/J)
increased susceptibility to autoimmune disorder J:99793
Eae37C57BL/10SnSg/?
(involves: B10.S * SJL/J)
increased susceptibility to autoimmune disorder J:99793
Eae38C57BL/10SnSg/?
(involves: B10.S * SJL/J)
increased susceptibility to autoimmune disorder J:99793
Eae39C57BL/10SnSg/Eae39RIIIS/J
(involves: B10.RIII * RIIIS/J)
CNS inflammation J:96204
Eae39RIIIS/J/Eae39RIIIS/J
(involves: B10.RIII * RIIIS/J)
CNS inflammation J:96204
Eae41C57BL/10SnSg/Eae41C57BL/10SnSg
(involves: B10.RIII * RIIIS/J)
CNS inflammation J:96204
Eae42C57BL/10SnSg/?
(involves: B10.S * SJL/J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:34892
Eae42SJL/J/?
(involves: B10.S * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:34892
Eae43B10.S/DvTe/?
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:53193
Eae43B10.S/DvTe/Eae43B10.S/DvTe
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:49054
Eae44aB10.S/DvTe/Eae44aB10.S/DvTe
(involves: B10.S/DvTe * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:56752
Eae44aB10.S/DvTe/Eae44aSJL/J
(involves: B10.S/DvTe * SJL/J)
brain inflammation J:49054
Eae44aSJL/J/Eae44aSJL/J
(involves: B10.S/DvTe * SJL/J)
brain inflammation J:49054
Eae44bB10.S/DvTe/Eae44bSJL/J
(involves: B10.S/DvTe * SJL/J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:56752
Eae44bSJL/J/Eae44bSJL/J
(involves: B10.S/DvTe * SJL/J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:56752
Eaf1tm1.1Zhow/Eaf1tm1.1Zhow
Eaf2tm1Zhow/Eaf2tm1Zhow
Tg(Pbsn-cre)4Prb/0

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * DBA/2)
prostate gland inflammation J:288972
Eaf1tm1.1Zhow/Eaf1tm1.1Zhow
Tg(Pbsn-cre)4Prb/0

(B6(Cg)-Eaf1tm1.1Zhow Tg(Pbsn-cre)4Prb)
prostate gland inflammation J:288972
Eaf2tm1Zhow/Eaf2tm1Zhow
(involves: 129P2/OlaHsd)
prostate gland inflammation J:288972
Eamcd1A/WySn/Eamcd1A/WySn
(B10.A-(D1Mit65-D1Mit334))
myocarditis J:145043
Eamcd2A/WySn/Eamcd2A/WySn
(involves: A.SW-H2s/J * B10.S-H2s/J)
myocarditis J:96562
Ebag9tm1Rehm/Ebag9tm1Rehm
(either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal CD8-positive, alpha beta T cell morphology J:152534
abnormal cytotoxic T cell physiology J:152534
abnormal memory T cell physiology J:152534
decreased susceptibility to bacterial infection J:152534
Ebf1em1(IMPC)Mbp/Ebf1+
(C57BL/6N-Ebf1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
small spleen J:211773
Ebf1m1Btlr/Ebf1m1Btlr
(C57BL/6J-Ebf1m1Btlr)
decreased B cell number J:265157
decreased IgD level J:265157
increased CD4-positive, alpha-beta T cell number J:265157
increased single-positive T cell number J:265157
increased T cell number J:265157
Ebf1m2Btlr/Ebf1m2Btlr
(C57BL/6J-Ebf1m2Btlr)
abnormal humoral immune response J:265158
decreased B cell number J:265158
decreased B-1 B cell number J:265158
decreased B-2 B cell number J:265158
decreased IgD level J:265158
decreased IgM level J:265158
increased B-1a cell number J:265158
increased B-1b cell number J:265158
increased CD4-positive, alpha-beta T cell number J:265158
increased IgM level J:265158
increased single-positive T cell number J:265158
increased T cell number J:265158
increased tumor necrosis factor secretion J:265158
Ebf1M3Btlr/Ebf1M3Btlr
(C57BL/6J-Ebf1M3Btlr)
decreased B-1 B cell number J:265160
increased CD4-positive, alpha-beta T cell number J:265160
increased single-positive T cell number J:265160
increased T cell number J:265160
Ebf1M4Btlr/Ebf1M4Btlr
(C57BL/6J-Ebf1M4Btlr)
decreased B cell number J:267560
decreased NK cell number J:267560
increased alpha-beta T cell number J:267560
increased CD4-positive, alpha-beta T cell number J:267560
increased CD8-positive, alpha-beta T cell number J:267560
Ebf1M5Btlr/Ebf1M5Btlr
(C57BL/6J-Ebf1M5Btlr)
abnormal lymphocyte morphology J:272841
decreased B cell number J:272841
decreased B-1 B cell number J:272841
Ebf1m6Btlr/Ebf1m6Btlr
(C57BL/6J-Ebf1m6Btlr)
abnormal lymphocyte morphology J:272842
decreased B cell number J:272842
decreased B-1 B cell number J:272842
decreased effector memory CD4-positive, alpha-beta T cell number J:272842
decreased IgD level J:272842
increased alpha-beta T cell number J:272842
increased CD4-positive, alpha-beta T cell number J:272842
increased CD8-positive, alpha-beta T cell number J:272842
Ebf1Serv/Ebf1+
(C57BL/6JAnu-Ebf1Serv)
decreased B cell number J:104190
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
decreased B-1 B cell number J:182210
decreased marginal zone B cell number J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6 * SJL)
arrested B cell differentiation J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
decreased germinal center B cell number J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Polr2atm1(cre/ERT2)Bbd/Polr2a+

(involves: C57BL/6 * SJL)
abnormal germinal center B cell physiology J:182210
arrested B cell differentiation J:182210
decreased B cell proliferation J:182210
decreased germinal center B cell number J:182210
decreased IgG1 level J:182210
decreased IgG3 level J:182210
decreased immature B cell number J:182210
decreased marginal zone B cell number J:182210
decreased pre-B cell number J:182210
decreased spleen germinal center number J:182210
decreased transitional stage B cell number J:182210
immune system phenotype J:182210
increased B cell apoptosis J:182210
increased B cell number J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Polr2atm1(cre/ERT2)Bbd/Polr2a+
Tg(BCL2)#Wehi/0

(involves: C57BL/6 * C57BL/6JWehi * SJL * SJL/JWehi)
decreased immature B cell number J:182210
decreased pre-B cell number J:182210
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Tg(Cr2-cre)3Cgn/0

(involves: C57BL/6 * SJL)
decreased B-1 B cell number J:182210
decreased marginal zone B cell number J:182210
Ebf1tm1Rug/Ebf1tm1Rug
(involves: 129S2/SvPas)
abnormal B cell morphology J:52607
absent B-1 B cells J:52607
absent mature B cells J:52607
arrested B cell differentiation J:52607
decreased IgM level J:52607
decreased pro-B cell number J:52607
Ebf1tm1Rug/Ebf1tm1Rug
(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6)
increased osteoclast cell number J:147179
Ebf2em1(IMPC)Mbp/Ebf2+
(C57BL/6N-Ebf2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Ebi3Gt716Lex/Ebi3Gt716Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal CD4-positive, alpha-beta T cell number J:286951
abnormal T cell activation J:286951
brain inflammation J:286951
decreased interleukin-10 secretion J:286951
increased CD8-positive, alpha-beta T cell number J:286951
increased interferon-gamma secretion J:286951
increased macrophage cell number J:286951
increased susceptibility to Coronaviridae infection J:286951
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:286951
Ebi3Gt716Lex/Ebi3Gt716Lex
Tg(DO11.10)10Dlo/0

(involves: 129S5/SvEvBrd * BALB/c * C3H * C57BL/6)
abnormal circulating interleukin level J:134148
abnormal T cell differentiation J:134148
decreased susceptibility to bacterial infection J:134148
increased circulating interleukin-17 level J:134148
increased interleukin-17 secretion J:134148
Ebi3tm1Nkma/Ebi3tm1Nkma
Faslpr/Faslpr

(MRL.Cg-Ebi3tm1Nkma Faslpr)
abnormal cytokine level J:181669
decreased circulating interferon-gamma level J:181669
increased circulating interleukin-4 level J:181669
increased IgE level J:181669
increased IgG1 level J:181669
increased IgG level J:181669
increased immunoglobulin level J:181669
Ebi3tm1Rsb/Ebi3tm1Rsb
(involves: 129X1/SvJ * C57BL/6)
abnormal immune system morphology J:81014
abnormal immune system physiology J:81014
abnormal T-helper 1 cell morphology J:97822
abnormal T-helper 2 cell morphology J:97822
decreased interleukin-4 secretion J:81014
decreased NK cell number J:81014
decreased susceptibility to induced colitis J:81014
decreased T-helper 2 cell number J:81014
increased interferon-gamma secretion J:81014
increased susceptibility to parasitic infection J:97822
Ebna1bp2em1(IMPC)Tcp/Ebna1bp2+
(C57BL/6NCrl-Ebna1bp2em1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
Ece1tm1Reh/Ece1tm1Reh
(involves: 129S6/SvEvTac * C57BL/6)
persistent cervical thymus J:46640
Ecm1tm1b(EUCOMM)Hmgu/Ecm1+
(C57BL/6N-Ecm1tm1b(EUCOMM)Hmgu/H)
decreased neutrophil cell number J:211773
Ecm1tm1Bsun/Ecm1tm1Bsun
(involves: 129 * C57BL/6)
abnormal T-helper 2 physiology J:168252
decreased IgE level J:168252
decreased susceptibility to type I hypersensitivity reaction J:168252
immune system phenotype J:168252
increased susceptibility to autoimmune disorder J:168252
Ecrg4tm1b(EUCOMM)Hmgu/Ecrg4tm1b(EUCOMM)Hmgu
(C57BL/6N-Ecrg4tm1b(EUCOMM)Hmgu/Orl)
decreased large unstained cell number J:211773
Ecscrtm1.1(KOMP)Vlcg/Ecscrtm1.1(KOMP)Vlcg
(C57BL/6N-Ecscrtm1.1(KOMP)Vlcg/Ucd)
abnormal thymus morphology J:211773
small thymus J:211773
EdaTa-6J/Y
(C57BL/6J Aw-J-EdaTa-6J/J)
blepharitis J:99510
conjunctivitis J:99510
corneal limbitis J:99510
eye inflammation J:99510
increased incidence of corneal inflammation J:99510
EdaTa-6J/Y
Tg(MMTVtTA)1Mam/0
Tg(tetO-Eda*A1)1Dsch/0

(involves: C57BL/6J)
immune system phenotype J:99510
Edc3em1(IMPC)Tcp/Edc3+
(C57BL/6NCrl-Edc3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Edc3em1(IMPC)Tcp/Edc3em1(IMPC)Tcp
(C57BL/6NCrl-Edc3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Eddm3btm1b(KOMP)Wtsi/Eddm3btm1b(KOMP)Wtsi
(C57BL/6N-Eddm3btm1b(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Edil3Tg(lacZ)1Tq/Edil3Tg(lacZ)1Tq
(Not Specified)
increased susceptibility to induced arthritis J:254384
Edil3tm1Tq/Edil3tm1Tq
(B6.129S6-Edil3tm1Tq)
abnormal cellular extravasation J:141063
abnormal leukocyte adhesion J:141063
abnormal neutrophil physiology J:141063
enhanced leukocyte tethering or rolling J:141063
Edil3tm1Tq/Edil3tm1Tq
Itgaltm1Bll/Itgaltm1Bll

(involves: 129 * C57BL/6)
abnormal cellular extravasation J:141063
abnormal neutrophil physiology J:141063
Ednratm1Ywa/Ednratm1Ywa
(129S/SvEv-Ednratm1Ywa)
ectopic thymus J:46639
thymus hypoplasia J:46639
Ednrbtm1Nrd/Ednrbtm1Nrd
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J)
abnormal mature B cell number J:233811
abnormal Peyer's patch morphology J:233811
abnormal spleen morphology J:233811
abnormal splenic cell ratio J:233811
decreased B cell number J:233811
decreased germinal center B cell number J:233811
decreased IgA level J:233811
decreased marginal zone B cell number J:233811
decreased spleen red pulp amount J:233811
decreased spleen weight J:233811
decreased spleen white pulp amount J:233811
large intestinal inflammation J:233811
small Peyer's patches J:233811
small spleen J:233811
Ednrbtm1Ywa/Ednrb+
(involves: 129S/SvEvBrd)
decreased acute inflammation J:103977
Ednrbtm1Ywa/Ednrbtm1Ywa
(involves: 129S5/SvEvBrd)
decreased acute inflammation J:103977
Eef1a1tm2Arge/Eef1a1+
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal double-positive T cell morphology J:197167
Eef1a2wst/Eef1a2wst
(B6C3Fe a/a-Eef1a2wst/J)
decreased plasma cell number J:7903
decreased spleen weight J:6766
decreased susceptibility to type IV hypersensitivity reaction J:6766
decreased thymus weight J:6766
lymphoid hypoplasia J:6766
small lymph nodes J:6766
Eef1a2wst/Eef1a2wst
(Not Specified)
thymus atrophy J:50410
Eef1dem1(IMPC)Mbp/Eef1d+
(C57BL/6NCrl-Eef1dem1(IMPC)Mbp/MbpMmucd)
increased neutrophil cell number J:211773
Eef1e1Gt(OST377244)Lex/Eef1e1+
(involves: 129S5/SvEvBrd * C57BL/6)
decreased splenocyte apoptosis J:96923
increased splenocyte proliferation J:96923
Efemp1tm2Lmar/Efemp1tm2Lmar
(involves: 129X1/SvJ * C57BL/6)
abnormal spleen morphology J:132043
decreased spleen weight J:132043
Efhd2tm1(KOMP)Vlcg/Efhd2tm1(KOMP)Vlcg
(C57BL/6-Efhd2tm1(KOMP)Vlcg)
abnormal response to infection J:228565
immune system phenotype J:228565
increased germinal center B cell number J:228565
increased IgE level J:228565
increased IgG1 level J:228565
increased IgG2a level J:228565
increased IgM level J:228565
increased plasma cell number J:228565
increased spleen germinal center size J:228565
Efnb1tm1.1Jwu/Efnb1tm1.1Jwu
Efnb2tm1.1Jwu/Efnb2tm1.1Jwu
Tg(Lck-cre)I540Jxm/0

(B6.Cg-Efnb2tm1.1Jwu Efnb1tm1.1Jwu Tg(Lck-cre)I540Jxm)
abnormal T cell differentiation J:178148
abnormal T-helper 1 cell differentiation J:178148
abnormal T-helper 17 cell differentiation J:178148
decreased CD4-positive, alpha-beta T cell number J:178148
decreased CD8-positive, alpha-beta T cell number J:178148
decreased DN4 thymocyte number J:178148
decreased double-positive T cell number J:178148
decreased spleen weight J:178148
decreased T cell number J:178148
decreased thymus weight J:178148
increased DN3 thymocyte number J:178148
increased double-negative T cell number J:178148
increased length of allograft survival J:178148
increased susceptibility to Riboviria infection J:178148
increased thymocyte apoptosis J:178148
small spleen J:178148
small thymus J:178148
spleen hypoplasia J:178148
thymus hypoplasia J:178148
Efnb1tm1.1Jwu/Efnb1tm1.1Jwu
Tg(Lck-cre)I540Jxm/0

(B6.Cg-Efnb1tm1.1Jwu Tg(Lck-cre)I540Jxm)
immune system phenotype J:178148
Efnb2tm1.1Jwu/Efnb2tm1.1Jwu
Tg(Lck-cre)I540Jxm/0

(B6.Cg-Efnb2tm1.1Jwu Tg(Lck-cre)I540Jxm)
immune system phenotype J:178148
Efnb2tm5.1Kln/Efnb2tm5.1Kln
(involves: C57BL/6)
abnormal afferent lymphatic vessel morphology J:95885
abnormal lymph circulation J:95885
abnormal lymphatic vessel morphology J:95885
Efnb2tm5.1Kln/Efnb2tm5.1Kln
(involves: CD-1)
abnormal lymphatic vessel morphology J:95885
Efnb2tm5.1Kln/Efnb2tm5.1Kln
Flt4tm1Ali/Flt4+

(involves: C57BL/6)
abnormal afferent lymphatic vessel morphology J:95885
abnormal lymphatic vessel morphology J:95885
Efnb2tm6Kln/Efnb2tm6Kln
(involves: C57BL/6)
abnormal lymph circulation J:95885
abnormal lymphatic vessel morphology J:95885
Efstm1Kale/Efs+
(either: (involves: 129X1/SvJ) or (involves: 129X1/SvJ * C57BL/6J))
increased IgA level J:103757
increased IgG level J:103757
increased inflammatory response J:103757
small intestinal inflammation J:103757
Efstm1Kale/Efstm1Kale
(either: (involves: 129X1/SvJ) or (involves: 129X1/SvJ * C57BL/6J))
abnormal interleukin secretion J:103757
abnormal T cell physiology J:103757
increased IgA level J:103757
increased IgG level J:103757
increased immunoglobulin level J:103757
increased inflammatory response J:103757
increased interferon-gamma secretion J:103757
kidney inflammation J:103757
liver inflammation J:103757
lung inflammation J:103757
small intestinal inflammation J:103757
Eftud2tm1b(KOMP)Wtsi/Eftud2+
(C57BL/6N-Eftud2tm1b(KOMP)Wtsi/Ics)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
EgfrMhdadsk5/Egfr+
(involves: 129S1/SvImJ * C3HeB/FeJ)
increased susceptibility to Coronaviridae infection J:243599
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:243599
Egfrtm1a(EUCOMM)Wtsi/Egfr+
(C57BL/6N-Egfrtm1a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:175295
Egfrtm1Dwt/Egfrtm1Dwt
Sox9tm3(cre)Crm/Sox9+

(involves: 129S6/SvEvTac * 129S7/SvEvBrd)
dermatitis J:229771
increased IgE level J:229771
increased T-helper 1 cell number J:229771
increased T-helper 2 cell number J:229771
increased T-helper 17 cell number J:229771
Egfrtm1Msi/Egfrtm1Msi
Tg(Alb1-cre)7Gsc/?

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
increased circulating tumor necrosis factor level J:125912
Egfrtm1Msi/Egfrtm1Msi
Tg(Mx1-cre)1Cgn/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
increased circulating tumor necrosis factor level J:125912
Egln1tm1.1Brei/Egln1tm1.1Brei
Tg(CD68-icre)1Bwlx/0

(involves: C57BL/6)
abnormal lymphocyte cell number J:194598
abnormal spleen morphology J:194598
enlarged spleen J:194598
increased spleen weight J:194598
Egln1tm1.1Fsl/Egln1+
(C57BL/6-Egln1tm1.1Fsl)
increased spleen weight J:202737
Egln1tm1Fong/Egln1tm1Fong
(involves: 129S6/SvEvTac * C57BL/6 * CD-1 * FVB/N * SJL)
abnormal lymph organ development J:114669
Egln1tm2.1Fsl/Egln1tm2.1Fsl
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(B6.Cg-Gt(ROSA)26Sortm9(cre/ESR1)Arte Egln1tm2.1Fsl)
increased spleen weight J:202737
Egln1tm2.1Fsl/Egln1tm2.1Fsl
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Hif1atm3Rsjo/Hif1atm3Rsjo

(B6.Cg-Gt(ROSA)26Sortm9(cre/ESR1)Arte Egln1tm2.1Fsl Hif1atm3Rsjo)
increased spleen weight J:202737
Egln1tm2.1Fsl/Egln1tm2.1Fsl
Pax3tm1(cre)Joe/Pax3+

(involves: 129 * C57BL/6)
increased spleen weight J:202737
Egln1tm2.2Fsl/Egln1+
(B6.Cg-Egln1tm2.2Fsl)
increased spleen weight J:202737
Egln1tm2Fong/Egln1tm2Fong
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+

(involves: 129S6/SvEvTac * C57BL/6)
abnormal splenic cell ratio J:132720
enlarged spleen J:132720
increased leukocyte cell number J:132720
Egln2tm1Fong/Egln2tm1Fong
Egln3tm1Fong/Egln3tm1Fong

(involves: 129S6/SvEvTac * C57BL/6)
abnormal splenic cell ratio J:132720
enlarged spleen J:132720
Egr1tm1b(NCOM)Mfgc/Egr1+
(C57BL/6N-Egr1tm1b(NCOM)Mfgc/Tcp)
increased lymphocyte cell number J:211773
Egr1tm1Jmi/Egr1tm1Jmi
(B6.129-Egr1tm1Jmi)
abnormal circulating tumor necrosis factor level J:128421
increased osteoclast cell number J:51107
liver inflammation J:128421
Egr1tm1Jmi/Egr1tm1Jmi
(involves: 129 * C57BL/6)
abnormal leukocyte cell number J:123870
abnormal leukocyte morphology J:123870
abnormal microglial cell physiology J:135238
abnormal neutrophil morphology J:123870
abnormal tumor necrosis factor level J:105638
decreased inflammatory response J:152898
immune system phenotype J:105638
increased lymphocyte cell number J:123870
increased spleen weight J:123870
Egr1tm1Jmi/Egr1tm1Jmi
Tg(Scgb1a1-rtTA,-tTS,tetO-TGFB1*)1Eli/?

(involves: 129 * C57BL/6)
lung inflammation J:92469
Ehbp1l1tm1a(EUCOMM)Wtsi/Ehbp1l1tm1a(EUCOMM)Wtsi
(C57BL/6N-Ehbp1l1tm1a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1+
(C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Nju)
increased neutrophil cell number J:211773
Ehmt2tm1.1Cza/Ehmt2tm1.1Cza
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
decreased IgG1 level J:160938
decreased interleukin-4 secretion J:160938
increased IgG2a level J:160938
increased interferon-gamma secretion J:160938
increased susceptibility to parasitic infection J:160938
Ehmt2tm1.1Cza/Ehmt2tm1.1Cza
Tg(VAV1-cre)1Graf/0

(involves: C57BL/6 * SJL)
decreased interleukin-4 secretion J:160938
decreased interleukin-5 secretion J:160938
decreased interleukin-13 secretion J:160938
increased interferon-gamma secretion J:160938
increased interleukin-17 secretion J:160938
increased susceptibility to parasitic infection J:160938
Eid2bem1(IMPC)J/Eid2b+
(C57BL/6NJ-Eid2bem1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Eif1adtm1b(EUCOMM)Hmgu/Eif1ad+
(C57BL/6N-Eif1adtm1b(EUCOMM)Hmgu/Bay)
increased large unstained cell number J:211773
Eif2aem1(IMPC)Mbp/Eif2aem1(IMPC)Mbp
(C57BL/6N-Eif2aem1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Eif2ak1em1(IMPC)Bay/Eif2ak1em1(IMPC)Bay
(C57BL/6N-Eif2ak1em1(IMPC)Bay/BayMmucd)
increased spleen weight J:211773
Eif2ak2em1(IMPC)Mbp/Eif2ak2em1(IMPC)Mbp
(C57BL/6N-Eif2ak2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Eif2ak2tm1Cwe/Eif2ak2tm1Cwe
(involves: 129S/SvEv * C57BL/6)
increased interleukin-4 secretion J:66112
increased susceptibility to Picornaviridae infection J:30617
increased susceptibility to type IV hypersensitivity reaction J:66112
increased T cell proliferation J:66112
Eif2ak2tm1Cwe/Eif2ak2tm1Cwe
(involves: 129)
immune system phenotype J:114555
Eif2ak2tm1Cwe/Eif2ak2tm1Cwe
Rnaseltm1Slvm/Rnaseltm1Slvm

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
increased susceptibility to Picornaviridae infection J:55974
Eif2ak2tm1Jcbe/Eif2ak2tm1Jcbe
(involves: 129S4/SvJae * BALB/c)
immune system phenotype J:53258
Eif2ak2tm1Jcbe/Eif2ak2tm1Jcbe
(involves: 129S4/SvJae)
immune system phenotype J:63671
increased susceptibility to Orthomyxoviridae infection J:63671
increased susceptibility to Riboviria infection J:167126, J:63671
Eif2ak3tm1.1Drc/Eif2ak3tm1.1Drc
Tg(Ela1-cre)16Eps/0

(involves: 129S6/SvEvTac)
acute pancreas inflammation J:129974
Eif2ak4m1Btlr/Eif2ak4m1Btlr
(C57BL/6J-Eif2ak4m1Btlr)
abnormal macrophage physiology J:173669
increased susceptibility to Adenoviridae infection J:173669
increased susceptibility to Herpesvirales infection J:173669
Eif2ak4tm1.2Dron/Eif2ak4tm1.2Dron
(involves: 129S6/SvEvTac * C57BL/6 * CBA)
abnormal cytokine secretion J:120813
abnormal dendritic cell physiology J:120813
Eif2b5tm1Itl/Eif2b5tm1Itl
(involves: 129S/SvEv)
abnormal microglial cell physiology J:192103
Eif2dem1(IMPC)Mbp/Eif2dem1(IMPC)Mbp
(C57BL/6N-Eif2dem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Eif2s1em1(IMPC)Mbp/Eif2s1+
(C57BL/6N-Eif2s1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Eif2s2em3(IMPC)Bay/Eif2s2+
(C57BL/6N-Eif2s2em3(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Eif4btm1.1Smoc/Eif4b+
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0

(involves: 129 * C57BL/6)
increased susceptibility to Riboviria infection J:311140
Eif4btm1.1Smoc/Eif4btm1.1Smoc
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+

(involves: 129 * C57BL/6)
decreased leukocyte cell number J:311140
decreased lymphocyte cell number J:311140
decreased NK cell number J:311140
increased macrophage cell number J:311140
increased neutrophil cell number J:311140
increased susceptibility to induced colitis J:311140
increased susceptibility to Orthomyxoviridae infection J:311140
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:311140
lung inflammation J:311140
small spleen J:311140
small thymus J:311140
Eif4btm1.1Smoc/Eif4btm1.1Smoc
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0

(involves: 129 * C57BL/6)
increased susceptibility to Orthomyxoviridae infection J:311140
Eif4g1em1(IMPC)Hmgu/Eif4g1+
(C57BL/6NCrl-Eif4g1em1(IMPC)Hmgu/Ieg)
decreased spleen weight J:211773
Elac2em1Afi/Elac2em1Afi
(C57BL/6N-Elac2em1Afi)
prostate gland inflammation J:336403
ElaneM1Btlr/ElaneM1Btlr
(C57BL/6J-ElaneM1Btlr)
decreased tumor necrosis factor secretion J:218967
Elanetm1(cre)Roes/Elanetm1(cre)Roes
(involves: 129)
decreased susceptibility to bacterial infection induced morbidity/mortality J:77597
increased susceptibility to infection induced morbidity/mortality J:77597
Elanetm1(cre)Roes/Elanetm1(cre)Roes
(involves: 129S6/SvEvTac)
impaired neutrophil recruitment J:137674
Elanetm1Link/Elanetm1Link
(involves: 129X1/SvJ * C57BL/6)
immune system phenotype J:131496
Elanetm1Sds/Elanetm1Sds
(129X1/SvJ-Elanetm1Sds)
abnormal neutrophil physiology J:47420
decreased susceptibility to bacterial infection induced morbidity/mortality J:47420
increased susceptibility to bacterial infection J:47420
increased susceptibility to bacterial infection induced morbidity/mortality J:47420
Elanetm1Sds/Elanetm1Sds
(involves: 129X1/SvJ * C57BL/6)
abnormal inflammatory response J:113463
Elapor1tm1b(EUCOMM)Hmgu/Elapor1+
(C57BL/6N-Elapor1tm1b(EUCOMM)Hmgu/Ics)
decreased lymphocyte cell number J:211773
Elavl1tm1.1Atas/Elavl1tm1.1Atas
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129X1/SvJ * C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:207013
decreased T cell proliferation J:207013
decreased T-helper 17 cell number J:207013
Elavl1tm1.1Dkon/Elavl1tm1.1Dkon
Lyz2tm1(cre)Ifo/Lyz2+

(B6.129P2-Elavl1tm1.1Dkon Lyz2tm1(cre)Ifo)
abnormal macrophage chemotaxis J:184388
immune system phenotype J:184388
increased circulating interleukin-1 beta level J:184388
increased circulating interleukin-6 level J:184388
increased circulating interleukin-12 level J:184388
increased circulating tumor necrosis factor level J:184388
increased macrophage cell number J:184388
increased monocyte cell number J:184388
increased susceptibility to endotoxin shock J:184388
increased susceptibility to induced colitis J:184388
Elavl1tm1.1Dkon/Elavl1tm1.1Dkon
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6J)
immune system phenotype J:184388
increased circulating interleukin-1 beta level J:184388
increased circulating interleukin-6 level J:184388
increased circulating interleukin-12 level J:184388
increased circulating tumor necrosis factor level J:184388
increased susceptibility to endotoxin shock J:184388
Elavl1tm1.1Thla/Elavl1+
(involves: 129S1/Sv)
spleen hypoplasia J:155109
thymus hypoplasia J:155109
Elavl1tm1Dkon/Elavl1tm1Dkon
Edil3Tg(Sox2-cre)1Amc/Edil3+

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal spleen development J:149149
absent spleen J:149149
Elavl1tm1Dkon/Elavl1tm1Dkon
Tg(Lck-cre)I57Jxm/0

(B6.Cg-Elavl1tm1Dkon Tg(Lck-cre)I57Jxm)
abnormal positive T cell selection J:148866
abnormal T cell physiology J:148866
abnormal thymocyte activation J:148866
decreased CD4-positive, alpha-beta T cell number J:148866
decreased CD8-positive, alpha-beta T cell number J:148866
increased double-negative T cell number J:148866
increased double-positive T cell number J:148866
increased single-positive T cell number J:148866
Elavl1tm1Dkon/Elavl1tm1Dkon
Tg(Lck-cre)I57Jxm/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(B6.Cg-Elavl1tm1Dkon Tg(Lck-cre)I57Jxm Tg(TcraH-Y,TcrbH-Y)71Vbo)
abnormal negative T cell selection J:148866
increased thymocyte number J:148866
Elavl1tm1Lix/Elavl1tm1Lix
Tg(Scgb1a1-rtTA)2Jaw/0
Tg(tetO-cre)1Jaw/0

(involves: 129 * C57BL/6)
decreased inflammatory response J:204952
lung inflammation J:204952
Elavl1tm1Thla/Elavl1tm1Thla
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+

(involves: 129)
abnormal B cell physiology J:155109
abnormal myeloid leukocyte morphology J:155109
decreased B cell apoptosis J:155109
decreased double-positive T cell number J:155109
decreased granulocyte number J:155109
decreased leukocyte cell number J:155109
increased granulocyte number J:155109
increased T cell apoptosis J:155109
lymph node hypoplasia J:155109
spleen hypoplasia J:155109
thymus hypoplasia J:155109
Elf1tm1Jml/Elf1tm1Jml
(Not Specified)
abnormal B cell differentiation J:100734
abnormal B cell physiology J:100734
Elf4em1Hdu/Elf4em1Hdu
(C57BL/6-Elf4em1Hdu)
abnormal CD4-positive T cell differentiation J:328935
abnormal interferon level J:328935
abnormal interleukin level J:328935
abnormal macrophage physiology J:328935
abnormal tumor necrosis factor level J:328935
increased susceptibility to viral infection J:328935
Elf4tm1Nim/Elf4tm1Nim
(B6.129S1-Elf4tm1Nim)
abnormal inflammatory response J:79568
abnormal lymphocyte morphology J:79568
abnormal lymphocyte physiology J:79568
abnormal NK cell physiology J:79568
abnormal T cell differentiation J:79568
decreased cytotoxic T cell cytolysis J:79568
decreased NK cell number J:79568
decreased NK T cell number J:79568
impaired natural killer cell mediated cytotoxicity J:79568
increased B cell number J:79568
increased B cell proliferation J:79568
increased T cell proliferation J:79568
large lymphoid organs J:79568
Elfn2tm1.1(KOMP)Vlcg/Elfn2tm1.1(KOMP)Vlcg
(C57BL/6N-Elfn2tm1.1(KOMP)Vlcg/Ucd)
increased eosinophil cell number J:211773
Elk1tm1Nor/Y
(involves: 129P2/OlaHsd * C57BL/6N)
immune system phenotype J:87597
Elk3tm1Wlyk/Elk3tm1Wlyk
(either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6))
lymphangiectasis J:71816
Elk4tm1a(EUCOMM)Wtsi/Elk4tm1a(EUCOMM)Wtsi
(C57BL/6N-Elk4tm1a(EUCOMM)Wtsi/H)
decreased CD4-positive, alpha-beta T cell number J:165965
decreased CD8-positive, alpha-beta T cell number J:165965
decreased mature B cell number J:165965
decreased T cell number J:165965
increased B cell number J:165965
increased T cell number J:165965
Elk4tm1Rtr/Elk4tm1Rtr
(either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6))
abnormal positive T cell selection J:88515
abnormal T cell selection J:88515
decreased CD4-positive, alpha-beta T cell number J:88515
decreased CD8-positive, alpha-beta T cell number J:88515
decreased single-positive T cell number J:88515
decreased T cell number J:88515
decreased thymocyte number J:88515
Elk4tm1Rtr/Elk4tm1Rtr
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129/Sv * C57BL/6 * DBA/2J)
abnormal positive T cell selection J:88515
decreased CD8-positive, alpha-beta T cell number J:88515
Elk4tm1Rtr/Elk4tm1Rtr
Tg(TcraTcrb)425Cbn/?

(involves: 129/Sv * C57BL/6)
abnormal positive T cell selection J:88515
abnormal splenic cell ratio J:88515
decreased CD4-positive, alpha-beta T cell number J:88515
Elk4tm1Rtr/Elk4tm1Rtr
Tg(TcrLCMV)327Sdz/?

(involves: 129/Sv * C57BL/6 * DBA/2)
abnormal positive T cell selection J:88515
decreased CD8-positive, alpha-beta T cell number J:88515
Elmo1M1Btlr/Elmo1M1Btlr
(C57BL/6J-Elmo1M1Btlr)
decreased B cell number J:265231
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:265231
decreased IgM level J:265231
impaired humoral immune response J:265231
increased B-1 B cell number J:265231
increased CD8-positive, alpha-beta memory T cell number J:265231
Elmo1m2Btlr/Elmo1m2Btlr
(C57BL/6J-Elmo1m2Btlr)
decreased B cell number J:265232
Elmo1m3Btlr/Elmo1m3Btlr
(C57BL/6J-Elmo1m3Btlr)
decreased central memory CD8 positive, alpha-beta T cell number J:271894
decreased NK cell number J:271894
increased CD8-positive, alpha-beta T cell number J:271894
Elmo1M4Btlr/Elmo1M4Btlr
(C57BL/6J-Elmo1M4Btlr)
abnormal B cell morphology J:271969
abnormal T cell morphology J:271969
decreased CD4-positive, alpha-beta T cell number J:271969
increased B-1 B cell number J:271969
increased CD8-positive, alpha-beta T cell number J:271969
Elmo1tm1a(EUCOMM)Wtsi/Elmo1tm1a(EUCOMM)Wtsi
(C57BL/6N-Elmo1tm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu
(C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H)
decreased B cell number J:165965
decreased leukocyte cell number J:165965
Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu
(C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H)
decreased large unstained cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
decreased spleen weight J:211773
increased eosinophil cell number J:211773
Elovl3tm1Jaco/Elovl3tm1Jaco
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
dermatitis J:88477
Elp1tm1Id/Elp1tm1.1Id
Tg(Hsp70-1-cre)6Arge/0

(involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
conjunctivitis J:188923
Elp1tm1Id/Elp1tm1Id
Tg(Hsp70-1-cre)6Arge/0

(involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
conjunctivitis J:188923
Elsgp1C57BL/6J/Elsgp1NZB/BlNJ
(involves: C57BL/6J * NZB/BlNJ)
abnormal immune serum protein physiology J:63674
Elsgp1NZB/BlNJ/Elsgp1NZB/BlNJ
(involves: C57BL/6J * NZB/BlNJ)
abnormal immune serum protein physiology J:63674
Elsgp1NZB/BlNJ/Elsgp1NZB/BlNJ
Elsgp2NZB/BlNJ/Elsgp2NZB/BlNJ

(involves: C57BL/6J * NZB/BlNJ)
abnormal immune serum protein physiology J:63674
Elsgp2C57BL/6J/Elsgp2NZB/BlNJ
(involves: C57BL/6J * NZB/BlNJ)
abnormal immune serum protein physiology J:63674
Elsgp2NZB/BlNJ/Elsgp2NZB/BlNJ
(involves: C57BL/6J * NZB/BlNJ)
abnormal immune serum protein physiology J:63674
Elsgp3C57BL/6J/Elsgp3NZB/BlNJ
(involves: C57BL/6J * NZB/BlNJ)
abnormal immune serum protein physiology J:63674
Elsgp3NZB/BlNJ/Elsgp3NZB/BlNJ
(involves: C57BL/6J * NZB/BlNJ)
abnormal immune serum protein physiology J:63674
Elsgp4NZB/BlNJ/Elsgp4NZB/BlNJ
(involves: BALB/cByJ * NZB/BlNJ)
abnormal immune serum protein physiology J:89134
Elsgp4NZW/LacJ/?
(involves: BALB/cByJ * NZW/LacJ)
abnormal immune serum protein physiology J:89134
Emc4tm1(KOMP)Wtsi/Emc4+
(C57BL/6N-Emc4tm1(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Emc8tm1b(EUCOMM)Hmgu/Emc8+
(C57BL/6N-Emc8tm1b(EUCOMM)Hmgu/H)
increased neutrophil cell number J:211773
Eme1tm1.1(KOMP)Wtsi/Eme1tm1.1(KOMP)Wtsi
(C57BL/6N-Eme1tm1.1(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Emp2tm1.1Tac/Emp2tm1.1Tac
Tg(Zp3-cre)93Knw/0

(involves: C57BL/6 * C57BL/6J * C57BL/6N)
increased leukocyte cell number J:243365
increased uterine NK cell number J:243365
Emsyem1(IMPC)Ccpcz/Emsy+
(C57BL/6NCrl-Emsyem1(IMPC)Ccpcz/Ccpcz)
increased NK cell number J:211773
Emv72a/Emv72a
(involves: BALB/cAnNCr * C57BL/6NCr)
abnormal cytotoxic T cell physiology J:194735
Emv72b/Emv72b
(CAnNCr.B6NCr-Emv72b)
abnormal cytotoxic T cell physiology J:194735
abnormal T cell morphology J:194735
Emv72b/Emv72b
(involves: BALB/cAnNCr * C57BL/6NCr)
abnormal cytotoxic T cell physiology J:194735
En1tm1(Tnf)Fpit/En1tm1(Tnf)Fpit
(involves: C57BL/6)
increased monocyte cell number J:170743
microgliosis J:170743
Endoutm1Tft/Endoutm1Tft
(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:208364
Endoutm1Tft/Endoutm1Tft
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0

(involves: 129S/SvEv * C57BL/6 * C57BL/6JSfd)
decreased activation-induced B cell apoptosis J:208364
immune system phenotype J:208364
increased autoantibody level J:208364
Engem1(IMPC)Mbp/Eng+
(C57BL/6N-Engem1(IMPC)Mbp/MbpMmucd)
increased neutrophil cell number J:211773
Enkurtm1Hmf/Enkurtm1Hmf
(involves: 129 * C57BL/6J)
abnormal spleen morphology J:253966
absent spleen J:253966
Enpeptm1Mdc/Enpeptm1Mdc
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:47424
Enpp1asj/Enpp1asj
(C57BL/6J-Enpp1asj/GrsrJ)
increased susceptibility to otitis media J:251638
joint inflammation J:174912
osteoarthritis J:174912
osteomyelitis J:174912
Enpp1ttw/Enpp1ttw
(involves: ICR)
osteoarthritis J:19124, J:37369
Enpp2tm1Lex/Enpp2+
(involves: 129S/SvEvBrd * C57BL/6J)
abnormal chemokine level J:103485
decreased circulating interleukin-6 level J:103485
decreased circulating tumor necrosis factor level J:103485
decreased susceptibility to endotoxin shock J:103485
Enpp3tm1Ktak/Enpp3tm1Ktak
(either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129S4/SvJae * BALB/c * C57BL/6))
abnormal basophil physiology J:223825
abnormal mast cell physiology J:223825
immune system phenotype J:223825
increased basophil cell number J:223825
increased IgE level J:223825
increased interleukin-4 secretion J:223825
increased mast cell number J:223825
increased susceptibility to type I hypersensitivity reaction J:223825
intestinal inflammation J:223825
lung inflammation J:223825
Enpp3tm1Ktak/Enpp3tm1Ktak
P2rx7tm1Gab/P2rx7tm1Gab

(either: (involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6) or (involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6))
immune system phenotype J:223825
increased basophil cell number J:223825
increased mast cell number J:223825
Entpd1tm1a(EUCOMM)Wtsi/Entpd1tm1a(EUCOMM)Wtsi
(C57BL/6N-Entpd1tm1a(EUCOMM)Wtsi/Ieg)
increased T cell number J:165965
Entpd1tm1Rdr/Entpd1tm1Rdr
(involves: 129S2/SvPas)
abnormal neutrophil physiology J:129091
spleen fibrosis J:57505
Entpd5tm1Rre/Entpd5tm1Rre
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal Kupffer cell morphology J:163795
liver inflammation J:163795
Entpd7tm1Ktak/Entpd7tm1Ktak
(B6.Cg-Entpd7tm1Ktak)
abnormal CD4-positive, alpha-beta T cell number J:191188
decreased susceptibility to bacterial infection J:191188
increased susceptibility to experimental autoimmune encephalomyelitis J:191188
increased T-helper 17 cell number J:191188
Eomestm1.1Bflu/Eomestm1.1Bflu
Tbx21tm1Glm/Tbx21tm1Glm
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL)
abnormal leukocyte migration J:163822
decreased CD4-positive, alpha-beta T cell number J:163822
decreased CD8-positive, alpha-beta T cell number J:163822
decreased interferon-gamma secretion J:163822
decreased memory T cell number J:163822
increased interleukin-4 secretion J:163822
increased interleukin-17 secretion J:163822
Eomestm1.1Bflu/Eomestm1.1Bflu
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal leukocyte migration J:163822
decreased memory T cell number J:163822
Eomestm1.1Twa/?
Il15tm1Imx/Il15tm1Imx

(involves: C57BL/6 * C57BL/6N)
abnormal NK cell differentiation J:210160
Eomestm1.1Twa/?
Tbx21tm1Glm/Tbx21tm1Glm

(involves: 129S6/SvEvTac * C57BL/6N)
abnormal NK cell differentiation J:210160
Eomestm1.1Twa/?
Tg(CD2-Tbx21)#Staka/?

(involves: C57BL/6N)
abnormal NK cell differentiation J:210160
Eomestm1.1Twa/?
Tg(Itgax-TGFBR2)1Flv/?

(involves: C3H * C57BL/6 * C57BL/6N)
abnormal NK cell differentiation J:210160
Eomestm1Apr/Eomes+
(involves: C57BL/6)
decreased memory T cell number J:112679
decreased NK cell number J:112679
Eomestm1Apr/Eomes+
Tbx21tm1Srnr/Tbx21tm1Srnr

(involves: C57BL/6)
decreased interferon-gamma secretion J:112679
decreased memory T cell number J:112679
decreased NK cell number J:112679
decreased NK T cell number J:112679
Eomestm1Srnr/Eomestm1Srnr
Tbx21tm1Srnr/Tbx21tm1Srnr
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal CD8-positive, alpha-beta T cell differentiation J:137655
abnormal immune system physiology J:137655
abnormal interleukin level J:137655
abnormal leukocyte physiology J:137655
abnormal T cell morphology J:137655
decreased CD8-positive, alpha-beta T cell number J:137655
decreased memory T cell number J:137655
increased neutrophil cell number J:137655
increased susceptibility to Riboviria infection J:137655
Eomestm1Srnr/Eomestm1Srnr
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
decreased memory T cell number J:137655
immune system phenotype J:137655
Ep300Plt6/Ep300+
Mpltm1Wsa/Mpltm1Wsa

(involves: 129S1/Sv * C57BL/6)
increased eosinophil cell number J:140200
Ep300Plt6/Ep300Plt6
(involves: 129S1/Sv * C57BL/6)
decreased B cell number J:140200
decreased eosinophil cell number J:140200
decreased leukocyte cell number J:140200
decreased lymphocyte cell number J:140200
Ep300tm1Pkb/Ep300+
Mybtm1Ssp/Myb+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
decreased thymocyte number J:98329
Ep300tm1Pkb/Ep300tm1Pkb
(involves: 129P2/OlaHsd * C57BL/6)
decreased thymocyte number J:98329
Ep300tm2Pkb/Ep300tm2Pkb
Tg(Lck-cre)548Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased single-positive T cell number J:105505
decreased thymocyte number J:105505
increased double-positive T cell number J:105505
small thymus J:105505
Epas1tm1.1Fsl/Epas1+
(involves: C57BL/6 * C57BL/6NTac)
increased leukocyte cell number J:199595
increased lymphocyte cell number J:199595
increased monocyte cell number J:199595
Epas1tm1.1Fsl/Epas1tm1.1Fsl
(involves: C57BL/6 * C57BL/6NTac)
increased leukocyte cell number J:199595
increased monocyte cell number J:199595
increased spleen weight J:199595
Epas1tm1Mcs/Epas1tm1.1Mcs
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129X1/SvJ * FVB/N)
enlarged spleen J:119731
Epb41tm1Cnby/Epb41tm1Cnby
(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ)
decreased spleen iron level J:77852
enlarged spleen J:77852
increased spleen red pulp amount J:77852
Epb42tm1Llp/Epb42tm1Llp
(involves: 129P2/OlaHsd * C57BL/6J)
increased spleen iron level J:67412
increased spleen weight J:67412
Epc1tm1a(EUCOMM)Wtsi/Epc1+
(Not Specified)
decreased leukocyte cell number J:175295
Epcamtm1.1Mcu/Epcamtm1.1Mcu
Tg(CD207-cre)1Dhka/0

(involves: 129 * C57BL/6 * C57BL/6J * SJL/J)
abnormal Langerhans cell morphology J:182665
abnormal Langerhans cell physiology J:182665
increased susceptibility to type IV hypersensitivity reaction J:182665
Epcamtm1.2Msiv/Epcamtm1.2Msiv
(involves: C57BL/6 * FVB/N * SJL)
small intestinal inflammation J:210901
Epdr1tm1b(NCOM)Mfgc/Epdr1tm1b(NCOM)Mfgc
(C57BL/6N-Epdr1tm1b(NCOM)Mfgc/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Epg5em1(IMPC)H/Epg5em1(IMPC)H
(C57BL/6NTac-Epg5em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased large unstained cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Epg5tm1Ygz/Epg5tm1Ygz
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N)
microgliosis J:196603
Epgntm1.1Msdr/Epgntm1.1Msdr
(involves: 129P2/OlaHsd * C57BL/6N)
increased spleen weight J:194427
Epha1tm1Sld/Epha1tm1Sld
(involves: 129 * C57BL/6J)
endometrium inflammation J:142722
vaginal inflammation J:142722
Epha2em1(IMPC)Mbp/Epha2em1(IMPC)Mbp
(C57BL/6N-Epha2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Epha3em1(IMPC)Mbp/Epha3em1(IMPC)Mbp
(C57BL/6N-Epha3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Epha6tm1b(KOMP)Wtsi/Epha6tm1b(KOMP)Wtsi
(C57BL/6N-Epha6tm1b(KOMP)Wtsi/Tcp)
abnormal spleen morphology J:211773
Ephb1em1(IMPC)Mbp/Ephb1em1(IMPC)Mbp
(C57BL/6N-Ephb1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Ephb2em1(IMPC)Mbp/Ephb2em1(IMPC)Mbp
(C57BL/6N-Ephb2em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Ephb4tm1.1Jwu/Ephb4tm1.1Jwu
Tg(KRT5-cre)1Tak/0

(involves: 129 * C3H * C57BL/6)
immune system phenotype J:206160
Ephb6tm1Jwu/Ephb6tm1Jwu
(involves: 129)
abnormal cytokine secretion J:94701
decreased susceptibility to experimental autoimmune encephalomyelitis J:94701
decreased susceptibility to type IV hypersensitivity reaction J:94701
decreased T cell proliferation J:94701
Ephb6tm1Tom/Ephb6tm1Tom
(involves: 129S4/SvJae * C57BL/6J)
immune system phenotype J:79747
Ephb6tm2Tom/Ephb6tm2Tom
(involves: 129S4/SvJae * C57BL/6J)
immune system phenotype J:79747
epi/?
(involves: CBA/J)
decreased leukocyte cell number J:27487
decreased lymphocyte cell number J:27487
increased neutrophil cell number J:27487
Epm2aTg(TcraK,TcrbK)TG-BFlv/Epm2a+
(involves: C57BL/6J * CBA/J)
increased CD8-positive, alpha-beta T cell number J:107545
Epm2aTg(TcraK,TcrbK)TG-BFlv/Epm2a+
Tg(Ela1-TAg)18Bri/0

(involves: C57BL/6 * CBA/J * SJL)
pancreas inflammation J:107545
EpoTg(TAg/Epo)134.3LCPjr/EpoTg(TAg/Epo)134.3LCPjr
(involves: C57BL/6 * CBA)
increased spleen weight J:79374
Eportm1.2Jtp/Eportm1.2Jtp
(involves: 129P2/OlaHsd * C57BL/6)
decreased spleen weight J:67205
Eppinem1(IMPC)Mbp/Eppinem1(IMPC)Mbp
(C57BL/6N-Eppinem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Eps15tm1a(KOMP)Wtsi/Eps15tm1a(KOMP)Wtsi
(B6JTyr;B6N-Eps15tm1a(KOMP)Wtsi/Wtsi)
decreased leukocyte cell number J:165965
Eps15tm1a(KOMP)Wtsi/Eps15tm1a(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
dermatitis J:213427
Eps15tm1Noff/Eps15tm1Noff
(B6.129-Eps15tm1Noff)
abnormal spleen B cell follicle morphology J:195689
abnormal spleen marginal zone morphology J:195689
abnormal spleen white pulp morphology J:195689
decreased B cell number J:195689
decreased leukocyte cell number J:195689
decreased lymphocyte cell number J:195689
immune system phenotype J:195689
increased marginal zone B cell number J:195689
Eps15tm1Noff/Eps15tm1Noff
(involves: 129 * C57BL/6)
abnormal marginal zone B cell morphology J:195689
increased marginal zone B cell number J:195689
increased transitional stage T1 B cell number J:195689
Epsti1em1Mjnh/Epsti1em1Mjnh
(Not Specified)
abnormal macrophage differentiation J:272013
decreased macrophage cell number J:272013
Epxtm1.1(cre)Jlee/Epx+
Gt(ROSA)26Sortm1(DTA)Lky/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * C57BL/6)
decreased eosinophil cell number J:198489
Epxtm1.1(cre)Jlee/Epxtm1.1(cre)Jlee
(B6.Cg-Epxtm1.1(cre)Jlee/Jlee)
immune system phenotype J:198489
Epxtm1b(EUCOMM)Wtsi/Epxtm1b(EUCOMM)Wtsi
(C57BL/6N-Epxtm1b(EUCOMM)Wtsi/Orl)
increased monocyte cell number J:211773
Epxtm1Nal/Epxtm1Nal
(involves: 129P2/OlaHsd * 129X1/SvJ)
abnormal eosinophil morphology J:70567
immune system phenotype J:70567
Epyctm1Mhok/Epyctm1Mhok
(involves: 129S7/SvEvBrd * C57BL/6J)
osteoarthritis J:222369
Erap1tm1.1Gnie/Erap1tm1.1Gnie
(involves: 129S6/SvEvTac * C57BL/6)
abnormal antigen presentation J:143988
abnormal cytotoxic T cell physiology J:143988
abnormal response to infection J:143988
decreased interferon-gamma secretion J:143988
decreased level of surface class I molecules J:143988
decreased T cell proliferation J:143988
Erap1tm1Dgen/Erap1tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:101679
thymus hyperplasia J:101679
Erap1tm1Iay/Erap1tm1Iay
(involves: C57BL/6)
abnormal cytotoxic T cell physiology J:111047
decreased level of surface class I molecules J:111047
Erap1tm1Luc/Erap1+
(involves: 129S6/SvEvTac)
abnormal antigen presentation J:122479
decreased level of surface class I molecules J:122479
Erap1tm1Luc/Erap1tm1Luc
(involves: 129S6/SvEvTac)
abnormal antigen presentation J:122479
abnormal CD8-positive, alpha-beta T cell physiology J:122479
abnormal lymphocyte physiology J:122479
decreased level of surface class I molecules J:122479
immune system phenotype J:122479
increased level of surface class I molecules J:122479
Erap1tm1Luc/Erap1tm1Luc
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrLCMV)327Sdz/Tg(TcrLCMV)327Sdz

(involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * C57BL/10SgSnAi * DBA/2)
immune system phenotype J:122479
Erap1tm1Nsha/Erap1tm1Nsha
(B6.129S6-Erap1tm1Nsha)
abnormal antigen presentation via MHC class I J:112389, J:116606
abnormal CD8-positive, alpha-beta T cell physiology J:112389, J:116606
abnormal cytokine secretion J:116606
decreased level of surface class I molecules J:112389
Erap1tm1Nsha/Erap1tm1Nsha
Tap1tm1Arp/Tap1tm1Arp

(B6.129-Erap1tm1Nsha Tap1tm1Arp)
abnormal antigen presentation via MHC class I J:112389
Erap1tm1Nsha/Erap1tm1Nsha
Tap1tm1Arp/Tap1tm1Arp

(involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/10 * DBA/2)
abnormal antigen presentation via MHC class I J:116606
Erars1DBA/2J/?
(involves: BXD2/TyJ * C57BL/6J * DBA/2J)
increased anti-nuclear antigen antibody level J:96064
increased immunoglobulin level J:96064
Erars2C57BL/6J/?
(involves: BXD2/TyJ * C57BL/6J * DBA/2J)
abnormal humoral immune response J:96064
increased immunoglobulin level J:96064
Erbb3tm1.1Dwt/Erbb3tm2.1Dwt
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
increased susceptibility to induced colitis J:152703
Erbb4tm1Grl/Erbb4tm1Grl
Tg(Myh6-ERBB4)HT2Gass/0

(involves: 129S1/Sv * 129X1/SvJ)
increased granulocyte number J:132190
lung inflammation J:132190
Ercc1tm1Jhjh/Ercc1tm1Jhjh
(involves: C57BL/6 * FVB/N)
abnormal class switch recombination J:92471
decreased B cell proliferation J:92471
spleen hypoplasia J:92471
Ercc1tm2Jhjh/Ercc1tm2Jhjh
(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:41161
Ercc2tm2(ERCC2)Jhjh/Ercc2tm2(ERCC2)Jhjh
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:76608
Ercc2tm2(ERCC2)Jhjh/Ercc2tm2(ERCC2)Jhjh
(involves: 129P2/OlaHsd)
immune system phenotype J:47993
Ercc2tm3Jhjh/Ercc2tm3Jhjh
(involves: 129 * C57BL/6J)
microgliosis J:179808
Ercc5tm1Shm/Ercc5tm1Shm
(involves: 129S2/SvPas * C57BL/6J)
decreased spleen weight J:53756
Ercc6tm1Gvh/Ercc6tm1Gvh
(involves: 129P2/OlaHsd * C57BL/6J)
microgliosis J:179808
Ercc6tm1Gvh/Ercc6tm1Gvh
Xpatm1Gvh/Xpatm1Hvs
Tg(Camk2a-cre)1Szi/0

(involves: 129P2/OlaHsd * C57BL/6J * CBA)
microgliosis J:179808
Ercc6tm1Gvh/Ercc6tm1Gvh
Xpatm1Gvh/Xpatm1Hvs
Tg(Pcp2-cre)2Mpin/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J)
microgliosis J:179808
Ercc6l2em1Mengf/Ercc6l2em1Mengf
(Not Specified)
abnormal class switch recombination J:311900
decreased IgA level J:311900
decreased IgG1 level J:311900
decreased IgG2b level J:311900
decreased IgG3 level J:311900
decreased IgG level J:311900
decreased T cell number J:311900
immune system phenotype J:311900
Ercc6l2em1Mengf/Ercc6l2em1Mengf
Nhej1em1Mengf/Nhej1em1Mengf

(Not Specified)
abnormal T cell receptor V(D)J recombination J:311900
Ercc6l2em2Mengf/Ercc6l2em2Mengf
(Not Specified)
abnormal class switch recombination J:311900
immune system phenotype J:311900
Ercc8tm1Jhjh/Ercc8tm1Jhjh
(involves: 129P2/OlaHsd * C57BL/6J)
microgliosis J:179808
Eregtm1Dwt/Eregtm1Dwt
(129S6/SvEvTac-Eregtm1Dwt)
increased susceptibility to induced colitis J:93327
Eregtm1Sawa/Eregtm1Sawa
(involves: 129X1/SvJ * C57BL/6J)
dermatitis J:92618
Ergem1(IMPC)Bay/Erg+
(C57BL/6N-Ergem1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
decreased leukocyte cell number J:211773
Ergmld2/Erg+
(involves: 129S1/Sv * C57BL/6)
decreased transitional stage B cell number J:137835
Ergmld2/Erg+
Mpltm1Wsa/Mpltm1Wsa

(B6.Cg-Mpltm1Wsa Ergmld2)
decreased leukocyte cell number J:137835
Ergtm1.1Iwamo/Ergtm1.1Iwamo
Tg(Gdf5-cre,-ALPP)1Kng/?

(involves: 129S4/SvJaeSor * C57BL/6 * FVB/N)
increased susceptibility to induced arthritis J:243715
osteoarthritis J:243715
Erlec1em1(IMPC)Mbp/Erlec1em1(IMPC)Mbp
(C57BL/6N-Erlec1em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Erlin1em1(IMPC)Tcp/Erlin1em1(IMPC)Tcp
(C57BL/6N-Erlin1em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
Ern1tm1Rjk/Ern1tm1Rjk
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal pro-B cell morphology J:106975
Ern1tm2.1Tiw/Ern1tm2.1Tiw
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0

(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * SJL)
small intestinal inflammation J:206084
Ern2m1Btlr/Ern2m1Btlr
(C57BL/6J-Ern2m1Btlr)
increased susceptibility to induced colitis J:216045
Ern2M2Btlr/Ern2M2Btlr
(C57BL/6J-Ern2M2Btlr)
increased susceptibility to induced colitis J:234237
Ern2m3Btlr/Ern2m3Btlr
(C57BL/6J-Ern2m3Btlr)
increased susceptibility to induced colitis J:236686
Ern2tm1Dron/Ern2tm1Dron
(either: 129S6/SvEvTac-Ern2tm1Dron or B6.129S6-Ern2tm1Dron)
increased susceptibility to induced colitis J:67934
Ero1aGt(XST171)Byg/Ero1aGt(XST171)Byg
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal macrophage physiology J:153833
decreased macrophage apoptosis J:153833
Errfi1tm1Gvw/Errfi1tm1Gvw
(Not Specified)
accelerated temporomandibular joint osteoarthritis J:100927
enlarged thymus J:100927
osteoarthritis J:100927
Errfi1tm1Gvw/Errfi1tm1Gvw
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv)
osteoarthritis J:100927
Errfi1tm3.1Gvw/Errfi1tm3.1Gvw
Tg(CMV-cre)1Cgn/0

(involves: 129 * 129S4/SvJaeSor * BALB/cJ)
osteoarthritis J:206807
Errfi1tm3.1Gvw/Errfi1tm3.1Gvw
Tg(Col2a1-cre)1Asz/0

(involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 * CBA)
osteoarthritis J:206807
Esamtm1Dvst/Esamtm1Dvst
(B6.129-Esam1tm1Dvst)
abnormal cellular extravasation J:124397
abnormal leukocyte migration J:124397
Esm1tm1.1Rha/Esm1tm1.1Rha
(involves: 129S6/SvEvTac * BALB/c * C57BL/6 * C57BL/6NTac)
abnormal cellular extravasation J:246778
EsmrDBA/2NCrj/EsmrDBA/2NCrj
(involves: C57BL/6NCrj * DBA/2NCrj)
decreased susceptibility to parasitic infection J:74563
Espl1Gt(XL058)Byg/Espl1+
Trp53tm1Tyj/Trp53tm1Tyj

(B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg)
abnormal splenocyte morphology J:174926
increased splenocyte proliferation J:174926
Espnje/?
f/f
Hps6ru/Hps6ru

(JE/LeJ)
abnormal mast cell degranulation J:37255
Esr1tm1.1Lja/Esr1tm1.1Mma
(involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6)
abnormal osteoclast physiology J:128135
Esr1tm1.1Mma/Esr1tm1.1Mma
(involves: 129S2/SvPas * C57BL/6)
abnormal immunoglobulin level J:171276
abnormal thymus physiology J:171276
Esr1tm1.1Ohl/Esr1tm1.1Ohl
(involves: 129S2/SvPas * C57BL/6)
abnormal immunoglobulin level J:171276
abnormal thymus physiology J:171276
Esr1tm1.1Scma/Esr1tm1.1Scma
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6)
abnormal osteoclast physiology J:156947
increased osteoclast cell number J:156947
Esr1tm1Arnal/Esr1tm1Arnal
(involves: C57BL/6)
abnormal immunoglobulin level J:171276
increased osteoclast cell number J:171276
Esr1tm1Ksk/Esr1tm1Ksk
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell number J:82423
abnormal class switch recombination J:82423
abnormal immunoglobulin level J:82423
abnormal lymph node cell ratio J:88156
abnormal spleen physiology J:88156
decreased CD4-positive, alpha-beta T cell number J:110416
decreased CD8-positive, alpha-beta T cell number J:110416
glomerulonephritis J:88156
increased anti-double stranded DNA antibody level J:88156
increased double-positive T cell number J:110416
increased IgG3 level J:88156
increased plasma cell number J:88156
increased spleen germinal center number J:88156
thymus hypoplasia J:110416
Esr1tm1Ksk/Esr1tm1Ksk
(involves: 129P2/OlaHsd)
decreased immature B cell number J:110923
decreased mature B cell number J:110923
spermatic granuloma J:60490
Esr1tm1Ksk/Esr1tm1Ksk
(involves: 129P2/OlaHsd * C57BL/6N)
abnormal B cell differentiation J:63462
abnormal thymus physiology J:111590
decreased B cell number J:63462
decreased immature B cell number J:63462
decreased mature B cell number J:63462
decreased thymocyte number J:111590
decreased thymus weight J:111590
Esr1tm1Ksk/Esr1tm1Ksk
Esr2tm1Unc/Esr2tm1Unc

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell number J:82423
abnormal class switch recombination J:82423
abnormal immunoglobulin level J:82423
decreased CD4-positive, alpha-beta T cell number J:110416
decreased CD8-positive, alpha-beta T cell number J:110416
decreased spleen weight J:110416
increased double-positive T cell number J:110416
thymus hypoplasia J:110416
Esr1tm1Ksk/Esr1tm1Ksk
Inhatm1Bay/Inhatm1Bay

(involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd)
liver inflammation J:84989
Esr2tm1.2Pcn/Esr2tm1.2Pcn
(involves: 129S2/SvPas * C57BL/6 * SJL)
immune system phenotype J:132171
Esr2tm1Mma/Esr2tm1Mma
(involves: 129S2/SvPas)
increased neutrophil cell number J:165719
Esr2tm1Unc/Esr2tm1Unc
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell number J:82423
abnormal leukopoiesis J:83617
abnormal lymphopoiesis J:83617
enlarged lymph nodes J:83617
enlarged spleen J:83617
increased granulocyte number J:83617
increased leukocyte cell number J:83617
increased monocyte cell number J:83617
increased neutrophil cell number J:83617
increased pre-B cell number J:83617
increased pro-B cell number J:83617
spleen hyperplasia J:83617
spleen hypoplasia J:110416
Esr2tm1Unc/Esr2tm1Unc
(involves: 129P2/OlaHsd)
colitis J:107308
urinary bladder inflammation J:122274
Esrp2em1(IMPC)Tcp/Esrp2em1(IMPC)Tcp
(C57BL/6NCrl-Esrp2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Esrratm1Vgi/Esrratm1Vgi
(involves: 129S1/Sv * 129X1/SvJ)
abnormal osteoclast differentiation J:160910
decreased osteoclast cell number J:160910
increased splenocyte number J:160910
Ess2tm1.1Nbioc/Ess2tm1.1Nbioc
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6N * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:339504
decreased CD4-positive, alpha-beta T cell number J:339504
decreased CD8-positive, alpha-beta T cell number J:339504
decreased CD8-positive, naive alpha-beta T cell number J:339504
decreased memory T cell number J:339504
immune system phenotype J:339504
increased gamma-delta T cell number J:339504
increased NK T cell number J:339504
Esyt2tm2b(KOMP)Wtsi/Esyt2+
(C57BL/6N-Esyt2tm2b(KOMP)Wtsi/Bay)
enlarged spleen J:211773
Etfbem1(IMPC)Hmgu/Etfb+
(C57BL/6NCrl-Etfbem1(IMPC)Hmgu/Ieg)
increased spleen weight J:211773
Etnk1tm1b(EUCOMM)Wtsi/Etnk1tm1b(EUCOMM)Wtsi
(C57BL/6N-Etnk1tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Ets1m1Anu/Ets1m1Anu
(C57BL/6NCrlAnu-Ets1m1Anu)
immune system phenotype J:104190
Ets1tm1.1Dds/Ets1+
(129S6/SvEvTac-Ets1tm1.1Dds)
abnormal thymus morphology J:121460
decreased memory T cell number J:121460
decreased thymocyte apoptosis J:121460
enlarged thymus J:121460
increased splenocyte apoptosis J:121460
increased thymus weight J:121460
Ets1tm1.1Dds/Ets1tm1.1Dds
(129S6/SvEvTac-Ets1tm1.1Dds)
abnormal CD8-positive, alpha beta T cell morphology J:121460
abnormal lymphopoiesis J:121460
abnormal spleen morphology J:121460
abnormal spleen red pulp morphology J:121460
abnormal thymus cortex morphology J:121460
abnormal thymus morphology J:121460
abnormal thymus subcapsular epithelium morphology J:121460
decreased B cell number J:121460
decreased CD4-positive, alpha-beta T cell number J:121460
decreased leukocyte cell number J:121460
decreased memory T cell number J:121460
decreased spleen weight J:121460
decreased thymocyte apoptosis J:121460
enlarged thymus J:121460
increased double-positive T cell number J:121460
increased splenocyte apoptosis J:121460
increased thymus weight J:121460
small spleen J:121460
Ets1tm1Fwa/Ets1tm1Fwa
(B6.129S4-Ets1tm1Fwa)
abnormal B cell differentiation J:93845
absent B-1a cells J:93845
decreased B cell number J:93845
decreased B cell proliferation J:93845
decreased mature B cell number J:93845
decreased pro-B cell number J:93845
immune system phenotype J:93845
increased B cell apoptosis J:93845
increased pro-B cell number J:93845
Ets1tm1Jml/Ets1tm1Jml
(involves: 129S/SvEv * C57BL/6)
abnormal CD8-positive, alpha-beta T cell differentiation J:125056
decreased CD4-positive, alpha-beta T cell number J:125056
decreased CD8-positive, alpha-beta T cell number J:125056
increased double-negative T cell number J:125056
thymus hypoplasia J:125056
Ets1tm1Jml/Ets1tm1Jml
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129S/SvEv * C57BL/6 * C57BL/6J * DBA/2J)
decreased CD8-positive, alpha-beta T cell number J:125056
immune system phenotype J:125056
increased double-negative T cell number J:125056
Ets1tm2Jml/Ets1tm2Jml
(involves: 129X1/SvJ * C57BL/6)
abnormal CD8-positive, alpha beta T cell morphology J:50627
abnormal leukocyte physiology J:50627
abnormal NK cell physiology J:50627
abnormal T cell activation J:50627
decreased NK cell number J:50627
decreased T cell number J:50627
decreased T cell proliferation J:50627
decreased thymocyte number J:50627
impaired natural killer cell mediated cytotoxicity J:50627
increased plasma cell number J:50627
Etv2tm1Dlim/Etv2tm2.1Dlim
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJaeSor * C57BL/6 * CBA)
decreased leukocyte cell number J:172687
impaired myelopoiesis J:172687
spleen hypoplasia J:172687
Etv6em1(IMPC)Rbrc/Etv6+
(C57BL/6NJcl-Etv6em1(IMPC)Rbrc/Rbrc)
increased large unstained cell number J:211773
increased spleen weight J:211773
Etv6em3Knic/Etv6+
(involves: C57BL/6J)
abnormal B cell number J:342774
Etv6tm1(RUNX1)Haho/Etv6+
Tg(CD2-icre)4Kio/0

(involves: 129S1/Sv * C57BL/6 * C57BL/10 * CBA/Ca)
immune system phenotype J:151639
Etv6tm1(RUNX1)Haho/Etv6+
Tg(Gata1-cre)1Sho/0

(involves: 129S1/Sv * C57BL/6 * CD-1 * Swiss Webster)
abnormal B cell differentiation J:151639
immune system phenotype J:151639
Etv6tm1(RUNX1)Haho/Etv6+
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * C57BL/6 * CBA)
abnormal lymphopoiesis J:151639
decreased B cell number J:151639
decreased lymphocyte cell number J:151639
decreased neutrophil cell number J:151639
immune system phenotype J:151639
myeloid hyperplasia J:151639
Etv6tm1(RUNX1)Haho/Etv6+
Tg(VAV1-cre)1Graf/0

(involves: 129S1/Sv * C57BL/6)
arrested B cell differentiation J:151639
decreased B cell number J:151639
decreased pre-B cell number J:151639
decreased pro-B cell number J:151639
Etv6tm2Sho/Etv6tm2Sho
Tg(Mx1-cre)1Cgn/?

(involves: 129S1/Sv * C57BL/6 * CBA)
decreased neutrophil cell number J:93052
Evc2em1(IMPC)Mbp/Evc2em1(IMPC)Mbp
(C57BL/6N-Evc2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Evltm1Lfr/Evltm1Lfr
(involves: 129X1/SvJ * C57BL/6)
abnormal leukocyte migration J:94077
Ewsr1tm1(ERG)Thr/Ewsr1+
Rag1tm1(cre)Thr/Rag1+

(involves: 129S/SvEv)
increased lymphocyte cell number J:98679
Ewsr1tm1b(EUCOMM)Wtsi/Ewsr1+
(C57BL/6N-Ewsr1tm1b(EUCOMM)Wtsi/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Ewsr1tm1Sblee/Ewsr1tm1Sblee
(involves: 129S6/SvEvTac * Black Swiss)
decreased double-positive T cell number J:122058
decreased immature B cell number J:122058
decreased leukocyte cell number J:122058
decreased mature B cell number J:122058
decreased pre-B cell number J:122058
spleen hypoplasia J:122058
thymus hypoplasia J:122058
exf/exf
(involves: C3H/HeN(MTV-))
conjunctivitis J:5649
increased susceptibility to bacterial infection J:5649
Exo1tm2Wed/Exo1tm2Wed
(involves: 129 * C57BL/6)
abnormal class switch recombination J:198719
abnormal somatic hypermutation frequency J:198719
Exo1tm3.1Wed/Exo1tm3.1Wed
(involves: 129 * C57BL/6)
immune system phenotype J:198719
Exoc6hbd/Exoc6hbd
(AB.Cg-Exoc6hbd)
decreased spleen iron level J:8251
enlarged spleen J:8251
Exph5tm1Tiz/Exph5tm1Tiz
(B6NJcl.Cg-Exph5tm1Tiz/Tiz)
abnormal interleukin secretion J:313415
abnormal T-helper 2 physiology J:313415
increased interleukin-5 secretion J:313415
increased interleukin-13 secretion J:313415
increased susceptibility to type I hypersensitivity reaction J:313415
Extl3em1(IMPC)Mbp/Extl3+
(C57BL/6N-Extl3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Eya1tm1Rilm/Eya1tm1Rilm
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * BALB/c) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
athymia J:79848, J:57313
Eya2em1(IMPC)Mbp/Eya2em1(IMPC)Mbp
(C57BL/6N-Eya2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
small spleen J:211773
Eya2tm2Px/Eya2tm2Px
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
small thymus J:311538
Eya4tm1Jse/Eya4tm1Jse
(involves: 129S6/SvEvTac * CBA/J)
increased susceptibility to otitis media J:131873
Ezh1tm1Sgon/Ezh1tm1Sgon
Tg(VAV1-cre)1Graf/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal myeloid leukocyte morphology J:193722
absent spleen germinal center J:193722
decreased B cell number J:193722
decreased immature B cell number J:193722
decreased pro-B cell number J:193722
decreased spleen red pulp amount J:193722
decreased spleen white pulp amount J:193722
lymphoid hypoplasia J:193722
small spleen J:193722
Ezh2em1Jbn/Ezh2+
(C57BL/6J-Ezh2em1Jbn)
increased spleen weight J:267184
Ezh2tm1.1Nesh/Ezh2+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129 * 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:239472
abnormal spleen white pulp morphology J:239472
enlarged lymph nodes J:239472
enlarged spleen J:239472
Ezh2tm1.1Nesh/Ezh2tm1.1Nesh
Cd19tm1(cre)Cgn/Cd19+

(involves: 129 * 129P2/OlaHsd * C57BL/6)
enlarged lymph nodes J:239472
enlarged spleen J:239472
Ezh2tm1Tara/Ezh2tm1Tara
Cd19tm1(cre)Cgn/?

(involves: 129P2/OlaHsd)
immune system phenotype J:83216
Ezh2tm1Tara/Ezh2tm1Tara
Ightm2Cgn/?
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:83216
Ezh2tm1Tara/Ezh2tm1Tara
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd)
decreased B cell proliferation J:199122
decreased germinal center B cell number J:199122
decreased IgG1 level J:199122
decreased IgG2b level J:199122
decreased IgG3 level J:199122
decreased spleen germinal center number J:199122
decreased spleen germinal center size J:199122
immune system phenotype J:199122
Ezh2tm1Tara/Ezh2tm1Tara
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal B cell differentiation J:83216
abnormal immunoglobulin V(D)J recombination J:83216
abnormal pro-B cell morphology J:83216
decreased immature B cell number J:83216
decreased pre-B cell number J:83216
Ezh2tm2Sho/Ezh2tm2.1Sho
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * C57BL/6 * CBA)
decreased double-positive T cell number J:182211
decreased thymocyte number J:182211
enlarged lymph nodes J:182211
enlarged spleen J:182211
increased double-negative T cell number J:182211
Ezh2tm2Sho/Ezh2tm2Sho
Pgrtm2(cre)Lyd/Pgr+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased uterine NK cell number J:290765
Ezh2tm2Sho/Ezh2tm2Sho
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * C57BL/6 * CBA)
decreased double-positive T cell number J:182211
decreased thymocyte number J:182211
enlarged lymph nodes J:182211
enlarged spleen J:182211
increased double-negative T cell number J:182211
Ezrtm2Aim/Ezrtm2Aim
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJae * C57BL/6 * DBA/2)
decreased interleukin-2 secretion J:143487
F2tm1Jld/F2tm1Jld
Tg(Mx1-cre)1Cgn/0

(B6.Cg-F2tm1Jld Tg(Mx1-cre)1Cgn)
increased susceptibility to bacterial infection J:144572
F2tm2Jld/F2+
(B6.129P2-F2tm2Jld)
decreased susceptibility to endotoxin shock J:174629
F2tm2Jld/F2+
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2J)
decreased susceptibility to induced arthritis J:174629
F2rtm1Ajc/F2rtm1Ajc
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:132733
F2rtm1Ajc/F2rtm1Ajc
F2rl1tm1Cgh/F2rl1tm1Cgh

(involves: 129S4/SvJae * C57BL/6)
increased susceptibility to endotoxin shock J:132733
F2rtm1Pago/F2rtm1Pago
(involves: 129P2/OlaHsd * C57BL/6)
decreased inflammatory response J:124648
decreased susceptibility to induced colitis J:94420
F2rtm1Pago/F2rtm1Pago
(B6.129P2-F2rtm1Pago)
immune system phenotype J:88245
F2rtm1Pago/F2rtm1Pago
(involves: 129P2/OlaHsd)
abnormal cytokine level J:133917
abnormal lymph node morphology J:133917
decreased susceptibility to endotoxin shock J:133917
enlarged mesenteric lymph nodes J:133917
F2rl1tm1Bpd/F2rl1tm1Bpd
(involves: 129P2/OlaHsd * C57BL/6)
decreased inflammatory response J:124648
increased inflammatory response J:96196
increased susceptibility to induced pancreatitis J:96196
F2rl1tm1Bpd/F2rl1tm1Bpd
(B6.129P2-F2rl1tm1Bpd)
decreased susceptibility to endotoxin shock J:88245
immune system phenotype J:88245
F2rl1tm1Cgh/F2rl1tm1Cgh
(involves: 129S4/SvJae * C57BL/6)
glomerulonephritis J:124303
immune system phenotype J:132733
impaired leukocyte tethering or rolling J:76626
F2rl1tm1Cgh/F2rl1tm1Cgh
(B6.129S4-F2rl1tm1Cgh)
decreased dendritic cell number J:113591
F2rl1tm1Jkaw/F2rl1tm1Jkaw
(involves: 129P2/OlaHsd * C57BL/6)
decreased susceptibility to type IV hypersensitivity reaction J:106127
F2rl1tm1Mslb/F2rl1tm1Mslb
(involves: 129X1/SvJ * C57BL/6)
decreased IgE level J:79757
decreased inflammatory response J:79757
F2rl1tm1Wrf/F2rl1tm1Wrf
(involves: 129P2/OlaHsd * C57BL/6)
decreased susceptibility to induced arthritis J:81119
F2rl1tm1Wrf/F2rl1tm1Wrf
(involves: 129P2/OlaHsd)
decreased circulating interleukin-18 level J:102762
liver inflammation J:102762
F2rl3tm1Cgh/F2rl3tm1Cgh
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:132733
F3tm1.1Dwr/F3tm1.1Dwr
(involves: 129S1/Sv * 129X1/SvJ * MF1 * Swiss)
abnormal cellular extravasation J:91165
abnormal leukocyte adhesion J:91165
decreased B cell number J:91165
decreased circulating interleukin-1 beta level J:91165
decreased circulating interleukin-6 level J:91165
decreased circulating tumor necrosis factor level J:91165
decreased leukocyte cell number J:91165
decreased neutrophil cell number J:91165
decreased susceptibility to endotoxin shock J:91165
impaired leukocyte tethering or rolling J:91165
F3tm1Dco/F3tm1Dco
Tg(F3)1Nmk/0

(B6.Cg-F3tm1Dco Tg(F3)1Nmk)
abnormal interleukin level J:88245
decreased susceptibility to endotoxin shock J:88245
F3tm1Gjb/F3+
(involves: 129X1/SvJ * C57BL/6)
abnormal chemokine secretion J:128891
abnormal macrophage physiology J:128891
decreased interleukin-6 secretion J:128891
immune system phenotype J:128891
F8tm1Kaz/Y
(involves: 129S4/SvJae * C57BL/6)
abnormal immune tolerance J:178969
F8tm1Kaz/Y
Tg(Alb-F8*R593C)T4Mcal/0

(involves: 129S4/SvJae * C57BL/6 * FVB/N)
immune system phenotype J:178969
F9tm1Dws/Y
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:44497
F11tm1Gjb/F11tm1Gjb
Proctm1Fjc/Proctm1Fjc

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal lymph circulation J:67398
abnormal lymph node cortex morphology J:67398
abnormal lymph node morphology J:67398
abnormal neutrophil morphology J:67398
decreased leukocyte cell number J:67398
decreased neutrophil cell number J:67398
enlarged lymph nodes J:67398
lung inflammation J:67398
lymph node hemorrhage J:67398
F11rtm1.1Dej/F11rtm1.1Dej
(Not Specified)
abnormal dendritic cell physiology J:92592
increased susceptibility to type IV hypersensitivity reaction J:92592
F11rtm1Dej/F11rtm1.1Dej
Tg(Tek-cre)1Ywa/0

(Not Specified)
immune system phenotype J:92592
Fa2hem1(IMPC)Mbp/Fa2hem1(IMPC)Mbp
(C57BL/6NCrl-Fa2hem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Fabp1tm1b(EUCOMM)Hmgu/Fabp1tm1b(EUCOMM)Hmgu
(C57BL/6N-Fabp1tm1b(EUCOMM)Hmgu/Cnrm)
decreased large unstained cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
Fabp2em1(IMPC)Hmgu/Fabp2em1(IMPC)Hmgu
(C57BL/6N-Fabp2em1(IMPC)Hmgu/Ieg)
enlarged lymph nodes J:211773
Fabp5tm1Kdo/Fabp5tm1Kdo
(involves: C57BL/6)
immune system phenotype J:75715
Faddtm1Mpa/Faddtm1Mpa
Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa
Tg(Alb1-cre)7Gsc/0

(involves: C57BL/6 * FVB/N)
liver inflammation J:118336
Faddtm1Mpa/Faddtm1Mpa
Mlkltm1.1Wsa/Mlkltm1.1Wsa
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0

(involves: C57BL/6 * C57BL/6N * DBA/2)
immune system phenotype J:312394
Faddtm1Mpa/Faddtm1Mpa
Mogtm1(cre)Gkl/Mog+

(involves: C57BL/6 * SJL)
decreased susceptibility to experimental autoimmune encephalomyelitis J:167475
immune system phenotype J:167475
Faddtm1Mpa/Faddtm1Mpa
Myd88tm1Aki/Myd88tm1Aki
Tg(Vil1-cre)997Gum/0

(B6.Cg-Faddtm1Mpa Myd88tm1Aki Tg(Vil1-cre)997Gum)
cecum inflammation J:175865
Faddtm1Mpa/Faddtm1Mpa
Tg(Vil1-cre)997Gum/0

(B6.Cg-Faddtm1Mpa Tg(Vil1-cre)997Gum)
cecum inflammation J:175865
colitis J:175865
Faddtm1Mpa/Faddtm1Mpa
Tnftm1Gkl/Tnftm1Gkl
Tg(Vil1-cre)997Gum/0

(B6.Cg-Faddtm1Mpa Tnftm1Gkl Tg(Vil1-cre)997Gum)
cecum inflammation J:175865
colitis J:175865
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd)33Wnt/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
immune system phenotype J:69617
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd)33Wnt/0
Tg(Lck-cre)I57Jxm/0

(involves: 129S4/SvJae * C57BL/6 * CBA * ICR)
abnormal T cell differentiation J:69617
decreased CD4-positive, alpha-beta T cell number J:69617
decreased CD8-positive, alpha-beta T cell number J:69617
decreased double-positive T cell number J:69617
increased B cell number J:69617
increased double-negative T cell number J:69617
thymus hypoplasia J:69617
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd)33Wnt/0
Tg(Lck-cre)I57Jxm/0
Tg(Tcra2C,Tcrb2C)1Dlo/0

(involves: 129S4/SvJae * C57BL/6 * C57L * CBA * ICR * SJL)
increased double-negative T cell number J:69617
thymus hypoplasia J:69617
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Cd4-cre)1Cwi/?

(involves: 129S4/SvJae * C57BL/6 * DBA/2)
decreased activated T cell number J:113207
decreased single-positive T cell number J:113207
immune system phenotype J:113207
increased B cell number J:113207
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Lck-cre)1Cwi/?

(involves: 129S4/SvJae)
decreased activated T cell number J:113207
decreased single-positive T cell number J:113207
immune system phenotype J:113207
increased B cell number J:113207
Faddtm1Wnt/Faddtm1Wnt
Tg(Fadd/EGFP)#Jizh/?
Tg(Mx1-cre)1Cgn/?

(involves: 129S4/SvJae * C57BL/6 * CBA)
spleen hypoplasia J:168722
thymus hypoplasia J:168722
Faddtm2.1Wnt/Faddtm2.1Wnt
Tg(Cd4-cre)1Cwi/?

(B6.Cg-Tg(Cd4-cre)1Cwi Faddtm2.1Wnt)
abnormal T cell proliferation J:162312
abnormal T cell subpopulation ratio J:162312
abnormal thymocyte apoptosis J:162312
enlarged lymph nodes J:162312
enlarged spleen J:162312
increased B cell number J:162312
increased susceptibility to parasitic infection J:162312
Fads1Gt(IST11525H2)Tigm/Fads1+
(C57BL/6-Fads1Gt(IST11525H2)Tigm)
decreased interferon-gamma secretion J:186265
decreased tumor necrosis factor secretion J:186265
Fads1Gt(IST11525H2)Tigm/Fads1Gt(IST11525H2)Tigm
(C57BL/6-Fads1Gt(IST11525H2)Tigm)
abnormal mononuclear cell morphology J:186265
decreased interferon-gamma secretion J:186265
decreased regulatory T cell number J:186265
decreased tumor necrosis factor secretion J:186265
Fads2tm1Mtna/Fads2tm1Mtna
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal spleen white pulp morphology J:153293
abnormal thymus cortex morphology J:153293
dermatitis J:153293
enlarged spleen J:153293
increased spleen red pulp amount J:153293
lymphoid hypoplasia J:153293
small thymus J:153293
Fads2tm1Wst/Fads2tm1Wst
(involves: 129P2/OlaHsd)
abnormal macrophage physiology J:140341
Fahem1(IMPC)Mbp/Fah+
(C57BL/6N-Fahem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Fahtm1Mgo/Fahtm1Mgo
(involves: 129S7/SvEvBrd * PT)
kidney inflammation J:77295
Fahtm1Mgo/Fahtm1Mgo
(involves: 129S7/SvEvBrd * C57BL)
liver inflammation J:27735
Fahtm1Mgo/Fahtm1Mgo
Hgdaku/Hgd+

(involves: 129S7/SvEvBrd * NB)
kidney inflammation J:77295
Faimtm1Kplm/Faimtm1Kplm
(involves: 129P2/OlaHsd * C57BL/6)
increased B cell apoptosis J:164184
increased thymocyte apoptosis J:164184
liver inflammation J:164184
Fam3aem1Cya/Fam3aem1Cya
(involves: C57BL/6)
increased macrophage cell number J:295206
increased NK T cell number J:295206
increased T cell number J:295206
Fam3dem1Wko/Fam3dem1Wko
(C57BL/6-Fam3dem1Wko)
abnormal cytokine level J:300819
abnormal neutrophil physiology J:304594
colitis J:300819
decreased Ly6C high monocyte number J:304594
decreased macrophage cell number J:304594
decreased neutrophil cell number J:304594
enlarged spleen J:300819
increased leukocyte cell number J:300819
increased neutrophil cell number J:304594, J:300819
increased susceptibility to colitis induced morbidity/mortality J:300819
increased susceptibility to induced colitis J:300819
Fam13atm1e(KOMP)Wtsi/Fam13atm1e(KOMP)Wtsi
(C57BL/6N-Fam13atm1e(KOMP)Wtsi)
white adipose tissue inflammation J:258290
Fam20ctm1.1Cqi/Fam20ctm1.1Cqi
Tg(Col1a1-cre)2Bek/0

(involves: 129S6/SvEvTac * CD-1)
dental pulp inflammation J:225679
periodontium inflammation J:225679
Fam53aem1(IMPC)Ccpcz/Fam53aem1(IMPC)Ccpcz
(C57BL/6N-Fam53aem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Fam72atm1.1(KOMP)Vlcg/Fam72atm1.1(KOMP)Vlcg
(C57BL/6NTac-Fam72atm1.1(KOMP)Vlcg)
abnormal class switch recombination J:326431
abnormal somatic hypermutation frequency J:326431
increased B cell apoptosis J:326431
increased germinal center B cell number J:326431
Fam72atm1.1(KOMP)Vlcg/Fam72atm1.1(KOMP)Vlcg
Msh2tm1Mak/Msh2tm1Mak

(C57BL/6NTac-Fam72atm1.1(KOMP)Vlcg Msh2tm1Mak)
abnormal class switch recombination J:326431
abnormal somatic hypermutation frequency J:326431
Fam81aem1(IMPC)Ccpcz/Fam81aem1(IMPC)Ccpcz
(C57BL/6N-Fam81aem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fam83bem1(IMPC)Mbp/Fam83bem1(IMPC)Mbp
(C57BL/6NCrl-Fam83bem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Fam83dem1(IMPC)Ccpcz/Fam83dem1(IMPC)Ccpcz
(C57BL/6N-Fam83dem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Fam83hem1(IMPC)Ccpcz/Fam83hem1(IMPC)Ccpcz
(C57BL/6N-Fam83hem1(IMPC)Ccpcz/Ccpcz)
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
Fam110btm1a(EUCOMM)Wtsi/Fam110b+
(C57BL/6N-Fam110btm1a(EUCOMM)Wtsi/Cnrm)
decreased mature B cell number J:165965
increased leukocyte cell number J:165965
Fam120cem1(IMPC)Ccpcz/Fam120cem1(IMPC)Ccpcz
(C57BL/6NCrl-Fam120cem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fam124aem1(IMPC)Ccpcz/Fam124aem1(IMPC)Ccpcz
(C57BL/6N-Fam124aem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fam151btm1b(EUCOMM)Hmgu/Fam151btm1b(EUCOMM)Hmgu
(C57BL/6N-Fam151btm1b(EUCOMM)Hmgu/H)
increased neutrophil cell number J:211773
Fam161aGt(462E7)Cmhd/Fam161aGt(462E7)Cmhd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
microgliosis J:214319
Fam161bem1(IMPC)Ccpcz/Fam161bem1(IMPC)Ccpcz
(C57BL/6N-Fam161bem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fam163atm2b(KOMP)Wtsi/Fam163atm2b(KOMP)Wtsi
(C57BL/6N-Fam163atm2b(KOMP)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Fam167aem1(IMPC)Ccpcz/Fam167aem1(IMPC)Ccpcz
(C57BL/6NCrl-Fam167aem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fam185aem1(IMPC)Ccpcz/Fam185aem1(IMPC)Ccpcz
(C57BL/6N-Fam185aem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Fam209tm1b(KOMP)Wtsi/Fam209tm1b(KOMP)Wtsi
(C57BL/6N-Fam209tm1b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Fam210atm1b(EUCOMM)Wtsi/Fam210a+
(involves: BALB/cJ * C57BL/6N)
increased osteoclast cell number J:261817
Fam210atm1c(EUCOMM)Wtsi/Fam210atm1c(EUCOMM)Wtsi
Tg(ACTA1-cre/Esr1*)2Kesr/0

(involves: C3H * C57BL/6N * SJL)
increased osteoclast cell number J:261817
Fam210atm1c(EUCOMM)Wtsi/Fam210atm1c(EUCOMM)Wtsi
Tg(CAG-cre/Esr1*)5Amc/0

(involves: C57BL/6N * CBA * SJL)
increased osteoclast cell number J:261817
Fam210btm1b(KOMP)Mbp/Fam210btm1b(KOMP)Mbp
(C57BL/6N-Fam210btm1b(KOMP)Mbp/Ucd)
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Fam219aem1(IMPC)Ccpcz/Fam219aem1(IMPC)Ccpcz
(C57BL/6N-Fam219aem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Fam221aem1(IMPC)Ccpcz/Fam221aem1(IMPC)Ccpcz
(C57BL/6N-Fam221aem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
increased neutrophil cell number J:211773
Fam227bem1(IMPC)Ccpcz/Fam227bem1(IMPC)Ccpcz
(C57BL/6NCrl-Fam227bem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fam234btm1a(EUCOMM)Wtsi/Fam234btm1a(EUCOMM)Wtsi
(C57BL/6N-Fam234btm1a(EUCOMM)Wtsi/Cnrm)
decreased CD8-positive, alpha-beta T cell number J:165965
Fan1tm1a(KOMP)Wtsi/Fan1tm1a(KOMP)Wtsi
(129S1.B6-Fan1tm1a(KOMP)Wtsi)
tubulointerstitial nephritis J:242198
Fancctm1Mab/Fancctm1Mab
Sod1tm1Cep/Sod1tm1Cep

(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymphocyte morphology J:71134
decreased leukocyte cell number J:71134
decreased lymphocyte cell number J:71134
decreased neutrophil cell number J:71134
Fancd2em1Tzh/Fancd2em1Tzh
(C57BL/6-Fancd2em1Tzh)
enlarged spleen J:284566
Fancltm1b(EUCOMM)Hmgu/Fancltm1b(EUCOMM)Hmgu
(C57BL/6N-Fancltm1b(EUCOMM)Hmgu/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Farp2tm1Akum/Farp2tm1Akum
(B6.Cg-Farp2tm1Akum)
abnormal osteoclast physiology J:166376
decreased osteoclast cell number J:166376
increased osteoclast cell number J:166376
Farsatm2a(EUCOMM)Wtsi/Farsa+
(C57BL/6N-Farsatm2a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Faslpr-cg/Faslpr-cg
(CBA/KlJms-Faslpr-cg/J)
abnormal hypersensitivity reaction J:24805, J:81770
abnormal lymph organ size J:24805
abnormal T cell differentiation J:24805
autoimmune response J:24805, J:81770
enlarged lymph nodes J:24805, J:81770
enlarged spleen J:24805
increased anti-nuclear antigen antibody level J:24805
increased autoantibody level J:81770
increased IgG level J:24805, J:81770
increased IgM level J:24805, J:81770
increased immunoglobulin level J:24805
increased spleen weight J:81770
Faslpr/Fas+
Tg(TcraTcrb)1100Mjb/?

(involves: C57BL/6 * MRL/Mp)
liver inflammation J:72817
Faslpr/Faslpr
(MRL/Mp-Faslpr)
abnormal B cell morphology J:108760
abnormal B cell receptor editing J:131138
abnormal cytotoxic T cell physiology J:7488
abnormal immune system organ morphology J:28885
abnormal immune system physiology J:28885
abnormal interleukin level J:8267
abnormal lymph node cell ratio J:6257
abnormal lymph node morphology J:27634
abnormal marginal zone B cell morphology J:131138
abnormal T cell morphology J:108760, J:8267
abnormal T cell physiology J:8267
abnormal T cell proliferation J:8267
abnormal T-helper 2 physiology J:6257
abnormal thymus medulla morphology J:28885
abnormal type III hypersensitivity reaction J:28885
blood vessel inflammation J:28885
decreased interleukin-2 secretion J:6638, J:7488
enlarged lymph nodes J:27634, J:108760, J:13757, J:28885
enlarged Peyer's patches J:28885
enlarged spleen J:28885
enlarged thymus J:13757
glomerulonephritis J:27634, J:13757, J:28885
increased anti-double stranded DNA antibody level J:27634, J:131138, J:6257
increased anti-erythrocyte antigen antibody level J:27634
increased anti-nuclear antigen antibody level J:27634, J:28885
increased anti-single stranded DNA antibody level J:27634
increased autoantibody level J:28885
increased IgA level J:28885
increased IgG1 level J:13757, J:28885
increased IgG2a level J:13757, J:28885
increased IgG2b level J:28885
increased IgG level J:27634
increased IgM level J:28885
increased immunoglobulin level J:13757, J:28885, J:6257
increased susceptibility to autoimmune disorder J:108760
increased thymus weight J:28885
lacrimal gland inflammation J:18512
lymph node hemorrhage J:27634
lymph node hyperplasia J:27634
lymph node necrosis J:27634
salivary gland inflammation J:18512
submandibular gland inflammation J:21965
thymus atrophy J:27634
thymus cortex atrophy J:13757, J:28885
thyroid gland inflammation J:28171
Faslpr/Faslpr
(MRL/Mp-Agtpbp1atms Faslpr)
enlarged lymph nodes J:103944
enlarged spleen J:103944
enlarged thymus J:103944
Faslpr/Faslpr
(NOD.MRL(B6)-Faslpr)
decreased susceptibility to autoimmune diabetes J:64051
Faslpr/Faslpr
(MRL/MpJ-Faslpr/J)
abnormal immunoglobulin level J:122315
CNS inflammation J:14151
conjunctivitis J:123192
decreased IgG level J:122315
decreased immature B cell number J:122315
decreased marginal zone B cell number J:122315
decreased mature B cell number J:122315
decreased spleen germinal center number J:122315
decreased transitional stage B cell number J:122315
enlarged lymph nodes J:92084, J:7454
glomerulonephritis J:92084, J:122315, J:127199, J:7454
increased anti-double stranded DNA antibody level J:92084, J:122315, J:7454
increased anti-nuclear antigen antibody level J:111811, J:92084, J:14151, J:7454
increased autoantibody level J:92084, J:14151
increased IgG level J:92084
increased immunoglobulin level J:122315, J:7454
increased neutrophil cell number J:127199
increased plasma cell number J:122315
increased susceptibility to systemic lupus erythematosus J:92084
lymph node hemorrhage J:7454
lymph node necrosis J:7454
salivary gland inflammation J:92084
Faslpr/Faslpr
(NOD.MRL-Faslpr)
decreased susceptibility to autoimmune diabetes J:78679
Faslpr/Faslpr
(involves: C3H * MRL/Mp)
autoimmune response J:1060
increased anti-nuclear antigen antibody level J:34296
increased spleen weight J:34296
increased susceptibility to systemic lupus erythematosus J:34296
increased susceptibility to type III hypersensitivity reaction J:34296
Faslpr/Faslpr
(B6.MRL-Faslpr/J)
abnormal NK cell physiology J:115033
abnormal splenic cell ratio J:132217
brain inflammation J:120427
CNS inflammation J:120427
decreased B cell apoptosis J:135830
enlarged lymph nodes J:119584
increased anti-double stranded DNA antibody level J:132217
increased anti-histone antibody level J:132217
increased anti-nuclear antigen antibody level J:132217
increased anti-single stranded DNA antibody level J:132217
increased autoantibody level J:132217
increased follicular B cell number J:132217
increased immature B cell number J:132217
increased marginal zone B cell number J:132217
increased splenocyte number J:132217
increased susceptibility to bacterial infection J:136745
increased susceptibility to Picornaviridae infection J:120427
increased transitional stage B cell number J:132217
lymph node hyperplasia J:132217
Faslpr/Faslpr
(MRL-Faslpr)
abnormal T-helper 2 physiology J:6257
enlarged lymph nodes J:126261
glomerulonephritis J:126261
increased anti-double stranded DNA antibody level J:126261
increased anti-nuclear antigen antibody level J:126261
increased IgG level J:126261
increased IgM level J:126261
increased immunoglobulin level J:6257
increased spleen weight J:126261
Faslpr/Faslpr
(MRL.Cg-Irf1tm1Mak Faslpr)
glomerulonephritis J:114771
increased anti-double stranded DNA antibody level J:114771
Faslpr/Faslpr
(C3.MRL-Faslpr/J)
abnormal B cell activation J:7454
abnormal T cell morphology J:7454
decreased eosinophil cell number J:106288
decreased interleukin-2 secretion J:7454
enlarged lymph nodes J:7454
glomerulonephritis J:7454
immune system phenotype J:7454
increased anti-double stranded DNA antibody level J:7454
increased anti-nuclear antigen antibody level J:7454
increased autoantibody level J:7454
increased immunoglobulin level J:7454
lymph node hemorrhage J:7454
lymph node hyperplasia J:7454
lymph node necrosis J:7454
Faslpr/Faslpr
(B6.MRL-Faslpr)
decreased interleukin-2 secretion J:6638
enlarged lymph nodes J:6638, J:135036, J:7454
enlarged spleen J:135036
glomerulonephritis J:135036, J:7454
increased anti-double stranded DNA antibody level J:7454
increased anti-nuclear antigen antibody level J:6638, J:135036
increased autoantibody level J:135036, J:7454
increased double-negative T cell number J:135036
increased immunoglobulin level J:7454
lymph node hemorrhage J:7454
lymph node necrosis J:7454
Faslpr/Faslpr
(AK.MRL-Faslpr)
enlarged lymph nodes J:7454
glomerulonephritis J:7454
increased anti-double stranded DNA antibody level J:7454
increased anti-nuclear antigen antibody level J:7454
increased autoantibody level J:7454
increased immunoglobulin level J:7454
lymph node hemorrhage J:7454
lymph node necrosis J:7454
Faslpr/Faslpr
(C3.MRL-Faslpr)
abnormal interleukin level J:8267
abnormal T cell morphology J:8267
abnormal T cell physiology J:8267
abnormal T cell proliferation J:8267
lacrimal gland inflammation J:1028
salivary gland inflammation J:1028
Faslpr/Faslpr
(MRL/MpJ-Faslpr)
abnormal leukocyte adhesion J:126009
abnormal leukocyte morphology J:126009
autoimmune response J:125114
blood vessel inflammation J:137066
decreased activated T cell number J:137066
decreased B cell number J:137066
decreased CD4-positive, alpha-beta T cell number J:137066
decreased CD8-positive, alpha-beta T cell number J:137066
enlarged lymph nodes J:137066
enlarged spleen J:137066
glomerulonephritis J:125114, J:132514, J:137066
impaired leukocyte tethering or rolling J:126009
increased anti-nuclear antigen antibody level J:137066
increased autoantibody level J:137066
increased double-negative T cell number J:137066
increased immunoglobulin level J:125114
Faslpr/Faslpr
(involves: MRL/Mp)
decreased macrophage apoptosis J:154647
increased susceptibility to bacterial infection J:50903
Faslpr/Faslpr
(involves: C57BL/6 * MRL/Mp)
enlarged spleen J:73396
increased anti-double stranded DNA antibody level J:73396
increased anti-single stranded DNA antibody level J:73396
increased IgA level J:73396
increased IgG1 level J:73396
increased IgG2a level J:73396
increased IgG2b level J:73396
increased IgG3 level J:73396
increased IgM level J:73396
lymph node hyperplasia J:73396
Faslpr/Faslpr
(involves: 129P2/OlaHsd * MRL)
enlarged lymph nodes J:26250
glomerulonephritis J:45448
increased double-negative T cell number J:26250
increased gamma-delta T cell number J:26250
kidney inflammation J:45448
Faslpr/Faslpr
Fcer1gtm1Tks/Fcer1gtm1Tks

(MRL.Cg-Fcer1gtm1Tks Faslpr)
arteritis J:106188
decreased susceptibility to type III hypersensitivity reaction J:106188
glomerulonephritis J:106188
immune system phenotype J:106188
increased anti-double stranded DNA antibody level J:106188
increased double-negative T cell number J:106188
increased IgG level J:106188
increased spleen weight J:106188
Faslpr/Faslpr
Havcr1tm1Kuch/Havcr1tm1Kuch

(B6.Cg-Havcr1tm1Kuch Faslpr)
abnormal immunoglobulin level J:186484
enlarged lymph nodes J:186484
enlarged spleen J:186484
increased activated T cell number J:186484
increased anti-double stranded DNA antibody level J:186484
increased autoantibody level J:186484
increased B cell number J:186484
increased CD4-positive, alpha-beta T cell number J:186484
increased CD8-positive, alpha-beta T cell number J:186484
increased double-negative T cell number J:186484
increased IgG1 level J:186484
increased IgG2a level J:186484
increased IgG2b level J:186484
increased IgG3 level J:186484
increased susceptibility to systemic lupus erythematosus J:186484
increased T cell number J:186484
Faslpr/Faslpr
Hspa13tm1.1Smoc/Hspa13tm1.1Smoc
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S * C57BL/6 * MRL/Mp)
decreased autoantibody level J:303927
decreased susceptibility to systemic lupus erythematosus J:303927
Faslpr/Faslpr
Ifnar1tm1Agt/Ifnar1tm1Agt

(MRL.Cg-Ifnar1tm1Agt Faslpr)
enlarged lymph nodes J:92084
glomerulonephritis J:92084
increased anti-nuclear antigen antibody level J:92084
increased autoantibody level J:92084
increased IgA level J:92084
increased IgG2b level J:92084
increased IgG3 level J:92084
increased IgG level J:92084
increased IgM level J:92084
increased susceptibility to systemic lupus erythematosus J:92084
salivary gland inflammation J:92084
Faslpr/Faslpr
Ifnar1tm1Agt/Ifnar1tm1Agt
Ifngr1tm1Agt/Ifngr1tm1Agt

(MRL.Cg-Ifngr1tm1Agt Ifnar1tm1Agt Faslpr)
decreased anti-nuclear antigen antibody level J:92084
decreased autoantibody level J:92084
decreased IgG level J:92084
decreased susceptibility to systemic lupus erythematosus J:92084
glomerulonephritis J:92084
increased IgG level J:92084
increased susceptibility to systemic lupus erythematosus J:92084
salivary gland inflammation J:92084
small lymph nodes J:92084
Faslpr/Faslpr
Ifngtm1Ts/Ifng+

(MRL.Cg-Ifngtm1Ts Faslpr)
abnormal macrophage chemotaxis J:123834
glomerulonephritis J:123834
increased autoantibody level J:123834
Faslpr/Faslpr
Ifngtm1Ts/Ifngtm1Ts

(MRL.Cg-Ifngtm1Ts Faslpr)
abnormal macrophage chemotaxis J:123834
immune system phenotype J:123834
kidney inflammation J:123834
lung inflammation J:123834
Faslpr/Faslpr
Ifngtm1Ts/Ifngtm1Ts

(involves: 129S7/SvEvBrd * DBA/1 * MRL/Mp)
abnormal lymph node size J:39600
abnormal spleen size J:39600
decreased anti-double stranded DNA antibody level J:39600
decreased anti-nuclear antigen antibody level J:39600
decreased autoantibody level J:39600
decreased double-negative T cell number J:39600
decreased IgA level J:39600
decreased IgG2a level J:39600
decreased IgG2b level J:39600
decreased IgM level J:39600
decreased immunoglobulin level J:39600
decreased susceptibility to systemic lupus erythematosus J:39600
enlarged lymph nodes J:39600
enlarged spleen J:39600
Faslpr/Faslpr
Ifngr1tm1Agt/Ifngr1tm1Agt

(MRL.Cg-Ifngr1tm1Agt Faslpr)
decreased anti-nuclear antigen antibody level J:92084
decreased autoantibody level J:92084
decreased IgA level J:92084
decreased IgG2a level J:92084
decreased IgG2b level J:92084
decreased IgG3 level J:92084
decreased IgM level J:92084
decreased susceptibility to systemic lupus erythematosus J:92084
glomerulonephritis J:92084
increased IgG1 level J:92084
increased IgG level J:92084
small lymph nodes J:92084
Faslpr/Faslpr
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+

(MRL.Cg-Faslpr Igh-Jtm2(3H9-VDJ*)Mwg)
abnormal B cell receptor editing J:131138
abnormal marginal zone B cell morphology J:131138
increased anti-double stranded DNA antibody level J:131138
Faslpr/Faslpr
Ighmtm1Cgn/Ighmtm1Cgn

(involves: 129S2/SvPas * C57BL/6 * MRL/Mp)
abnormal humoral immune response J:119584
abnormal immunoglobulin level J:119584
arrested B cell differentiation J:119584
decreased IgM level J:119584
decreased mature B cell number J:119584
enlarged lymph nodes J:119584
increased autoantibody level J:119584
increased T cell number J:119584
Faslpr/Faslpr
Il2ratm1Dw/Il2ratm1Dw
Tg(CD2-Ccdc86)1Hfuj/?

(B6.Cg-Il2ratm1Dw Faslpr Tg(CD2-Ccdc86)1Hfuj)
enlarged spleen J:151722
Faslpr/Faslpr
Il4tm1Cgn/Il4tm1Cgn

(MRL.Cg-Il4tm1Cgn Faslpr)
glomerulonephritis J:132514
lacrimal gland inflammation J:132514
Faslpr/Faslpr
Il4tm1Cgn/Il4tm1Cgn

(involves: 129P2/OlaHsd * C57BL/6J * MRL/Mp)
abnormal lymph node size J:39600
abnormal spleen size J:39600
decreased anti-nuclear antigen antibody level J:39600
decreased IgA level J:39600
decreased IgE level J:39600
decreased IgG1 level J:39600
decreased IgG3 level J:39600
decreased immunoglobulin level J:39600
decreased susceptibility to systemic lupus erythematosus J:39600
enlarged spleen J:39600
increased spleen weight J:39600
spleen hyperplasia J:39600
Faslpr/Faslpr
Il27ratm1Mak/Il27ratm1Mak

(MRL.Cg-Il27ratm1Mak Faslpr)
abnormal T-helper 2 physiology J:122148
decreased anti-double stranded DNA antibody level J:122148
decreased IgG2a level J:122148
decreased interferon-gamma secretion J:122148
decreased susceptibility to systemic lupus erythematosus J:122148
glomerulonephritis J:122148
immune system phenotype J:122148
increased circulating interleukin-4 level J:122148
increased circulating interleukin-5 level J:122148
increased IgE level J:122148
increased IgG1 level J:122148
Faslpr/Faslpr
Irf1tm1Mak/Irf1+

(MRL.Cg-Irf1tm1Mak Faslpr)
glomerulonephritis J:114771
immune system phenotype J:114771
increased anti-double stranded DNA antibody level J:114771
increased CD4-positive, alpha-beta T cell number J:114771
Faslpr/Faslpr
Irf1tm1Mak/Irf1tm1Mak

(MRL.Cg-Irf1tm1Mak Faslpr)
abnormal cytokine secretion J:114771
decreased anti-double stranded DNA antibody level J:114771
glomerulonephritis J:114771
immune system phenotype J:114771
increased CD4-positive, alpha-beta T cell number J:114771
Faslpr/Faslpr
Itfg2Gt(OST215121)Lex/Itfg2Gt(OST215121)Lex

(involves: 129S5/SvEvBrd * C57BL/6J * MRL/Mp)
decreased B cell number J:205951
enlarged lymph nodes J:205951
enlarged spleen J:205951
increased anti-double stranded DNA antibody level J:205951
increased anti-nuclear antigen antibody level J:205951
increased double-negative T cell number J:205951
increased IgG2a level J:205951
increased IgM level J:205951
increased susceptibility to systemic lupus erythematosus J:205951
Faslpr/Faslpr
Kdelr1m1Btlr/Kdelr1m1Btlr

(involves: C57BL/6J * MRL/Mp)
immune system phenotype J:224970
Faslpr/Faslpr
Nos2tm1Mrl/Nos2tm1Mrl

(involves: 129S7/SvEvBrd * MRL)
abnormal immunoglobulin level J:42666
decreased IgG level J:42666
decreased IgM level J:42666
immune system phenotype J:42666
Faslpr/Faslpr
Pou2af1tm1Pmt/Pou2af1tm1Pmt

(involves: 129P2/OlaHsd * C57BL/6 * MRL)
abnormal T cell number J:125114
autoimmune response J:125114
decreased immunoglobulin level J:125114
decreased plasma cell number J:125114
increased B cell number J:125114
Faslpr/Faslpr
Selptm1Bay/Selptm1Bay

(MRL.Cg-Selptm1Bay Faslpr)
abnormal chemokine secretion J:127199
abnormal leukocyte adhesion J:126009
dermatitis J:127199
glomerulonephritis J:127199
impaired leukocyte tethering or rolling J:126009
increased neutrophil cell number J:127199
Faslpr/Faslpr
Selplgtm1Fur/Selplgtm1Fur

(MRL.Cg-Selplgtm1Fur Faslpr)
abnormal chemokine level J:127199
dermatitis J:127199
glomerulonephritis J:127199
Faslpr/Faslpr
Sh2d1arpl/Sh2d1arpl

(MRL/Mp-Faslpr Sh2d1arpl)
abnormal immune system physiology J:126261
increased anti-nuclear antigen antibody level J:126261
Faslpr/Faslpr
Spp1tm1Rit/Spp1tm1Rit

(involves: 129S7/SvEvBrd * C57BL/6 * MRL/Mp)
enlarged spleen J:73396
increased anti-double stranded DNA antibody level J:73396
increased anti-single stranded DNA antibody level J:73396
increased IgA level J:73396
increased IgG1 level J:73396
increased IgG2a level J:73396
increased IgG2b level J:73396
increased IgG3 level J:73396
increased IgM level J:73396
kidney inflammation J:73396
lymph node hyperplasia J:73396
Faslpr/Faslpr
Tcratm1Mjo/Tcra+

(MRL.Cg-Tcratm1Mjo Faslpr)
immune system phenotype J:108590
Faslpr/Faslpr
Tcratm1Mjo/Tcratm1Mjo

(involves: 129P2/OlaHsd * MRL)
immune system phenotype J:26250
increased gamma-delta intraepithelial T cell number J:26250
increased gamma-delta T cell number J:26250
increased T cell number J:26250
kidney inflammation J:45448
Faslpr/Faslpr
Tcratm1Mjo/Tcratm1Mjo

(involves: 129P2/OlaHsd * 129S2/SvPas * MRL)
decreased autoantibody level J:38492
decreased immunoglobulin level J:38492
Faslpr/Faslpr
Tg(CD2-Foxj1)#Stlp/0

(MRL.Cg-Faslpr Tg(CD2-Foxj1)#Stlp)
abnormal T cell physiology J:122222
decreased CD4-positive, alpha-beta T cell number J:122222
decreased susceptibility to systemic lupus erythematosus J:122222
enlarged lymph nodes J:122222
enlarged spleen J:122222
increased anti-nuclear antigen antibody level J:122222
increased double-negative T cell number J:122222
kidney inflammation J:122222
liver inflammation J:122222
lung inflammation J:122222
salivary gland inflammation J:122222
Faslpr/Faslpr
Tg(H2-K-Cd86)27All/0

(involves: C57BL/6 * CBA * MRL/MpJ)
decreased B cell number J:112475
Faslpr/Faslpr
Tg(Ins2-Fasl)24Ach/0

(NOD.Cg-Faslpr Tg(Ins2-Fasl)24Ach)
decreased susceptibility to autoimmune diabetes J:81416
Faslpr/Faslpr
Tg(INS-Il10)#Sar/0

(NOD.Cg-Faslpr Tg(INS-Il10)#Sar)
increased susceptibility to autoimmune diabetes J:64051
insulitis J:64051
Faslpr/Faslpr
Tlr7tm1Flv/Y

(involves: 129S1/Sv * C57BL/6 * MRL/Mp)
abnormal B cell activation J:113557
abnormal CD4-positive, alpha beta T cell morphology J:113557
abnormal lymph node size J:113557
abnormal plasmacytoid dendritic cell physiology J:113557
decreased autoantibody level J:113557
decreased double-negative T cell number J:113557
decreased IgG2a level J:113557
decreased IgG3 level J:113557
decreased spleen weight J:113557
decreased susceptibility to systemic lupus erythematosus J:113557
increased anti-chromatin antibody level J:113557
increased autoantibody level J:113557
Faslpr/Faslpr
Tlr9tm1Aki/Tlr9tm1Aki

(B6.Cg-Tlr9tm1Aki Faslpr)
autoimmune response J:135036
decreased IgM level J:135036
enlarged lymph nodes J:135036
enlarged spleen J:135036
glomerulonephritis J:135036
increased double-negative T cell number J:135036
increased IgG level J:135036
Faslpr/Faslpr
Tlr9tm1Aki/Tlr9tm1Aki

(MRL.Cg-Tlr9tm1Aki Faslpr)
abnormal B cell activation J:113557
abnormal plasmacytoid dendritic cell physiology J:113557
decreased autoantibody level J:113557
enlarged lymph nodes J:113557
enlarged spleen J:113557
glomerulonephritis J:113557
increased autoantibody level J:113557
increased CD4-positive, alpha-beta T cell number J:113557
increased circulating interferon-alpha level J:113557
increased double-negative T cell number J:113557
increased IgG2a level J:113557
increased IgG3 level J:113557
increased IgG level J:113557
increased susceptibility to systemic lupus erythematosus J:113557
kidney inflammation J:113557
Faslpr/Faslpr
Tnfrsf1atm1.1Gkl/Tnfrsf1atm1.1Gkl

(involves: 129/Sv * C57BL/6)
liver inflammation J:92470
Faslpr/Faslpr
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk

(MRL.Cg-Tnfrsf9tm1Byk Faslpr)
enlarged lymph nodes J:127197
enlarged spleen J:127197
increased anti-nuclear antigen antibody level J:127197
increased B-1 B cell number J:127197
increased B-2 B cell number J:127197
increased CD4-positive, alpha-beta T cell number J:127197, J:126929
increased double-negative T cell number J:127197, J:126929
increased immunoglobulin level J:127197
increased interleukin-4 secretion J:126929
increased spleen germinal center number J:127197
increased susceptibility to systemic lupus erythematosus J:127197
lacrimal gland inflammation J:126929
Faslpr/Faslpr
Tnfrsf13cBcmd1/Tnfrsf13c+

(MRL.Cg-Tnfrsf13cBcmd1 Faslpr)
decreased B cell number J:122315
decreased marginal zone B cell number J:122315
Faslpr/Fastm1.1Cgn
(involves: C57BL/6 * MRL)
abnormal immune system morphology J:114948
enlarged lymph nodes J:114948
enlarged spleen J:114948
Faslpr/Fastm1Cgn
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * MRL)
enlarged lymph nodes J:114948
enlarged spleen J:114948
increased double-negative T cell number J:114948
Fasm1Btlr/Fasm1Btlr
(C57BL/6J-Fasm1Btlr)
decreased CD4-positive, alpha-beta T cell number J:216052
decreased CD8-positive, alpha-beta T cell number J:216052
increased neutrophil cell number J:216052
increased NK cell number J:216052
Fasm2Btlr/Fasm2Btlr
(C57BL/6J-Fasm2Btlr)
increased central memory CD4-positive, alpha-beta T cell number J:271891
increased effector memory CD4-positive, alpha-beta T cell number J:271891
Fastheo/Fastheo
(either: (involves: C57BL/6JAnu * C57BL/10SnSg * C57BR/cd) or (involves: C57BL/6JAnu * C57BL/10SnSg * C57BR/cd * CBA/CaJAnu))
enlarged lymph nodes J:104190
increased anti-nuclear antigen antibody level J:104190
Fastm1.1Cgn/Fastm1.1Cgn
(involves: C57BL/6)
abnormal immune system morphology J:114948
enlarged lymph nodes J:114948
enlarged spleen J:114948
Fastm1Ach/Fastm1Ach
Tg(GZMB-cre)1Jcb/?

(involves: C57BL/6 * FVB/N)
increased anti-nuclear antigen antibody level J:123556
increased double-positive T cell number J:123556
Fastm1Ach/Fastm1Ach
Tg(Itgax-cre,-EGFP)4097Ach/?

(Not Specified)
abnormal spleen morphology J:123556
abnormal spleen periarteriolar lymphoid sheath morphology J:123556
enlarged spleen J:123556
increased anti-nuclear antigen antibody level J:123556
increased dendritic cell number J:123556
increased IgG level J:123556
increased IgM level J:123556
increased immunoglobulin level J:123556
Fastm1Ach/Fastm1Ach
Tg(Lck-cre)548Jxm/?

(involves: C57BL/6 * CBA)
increased anti-nuclear antigen antibody level J:123556
increased double-positive T cell number J:123556
Fastm1Cgn/Fastm1Cgn
(C57BL/6-Fastm1Cgn)
immune system phenotype J:114948
Fastm1Cgn/Fastm1Cgn
Cd19tm1(cre)Cgn/Cd19+
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Tg(Cd4-cre)1Cwi Cd19tm1(cre)Cgn Fastm1Cgn)
increased anti-single stranded DNA antibody level J:114948
Fastm1Cgn/Fastm1Cgn
Mogtm1(cre)Gkl/Mog+

(involves: C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:114741
immune system phenotype J:114741
Fastm1Cgn/Fastm1Cgn
Mogtm1(cre)Gkl/Mog+
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak

(involves: 129S2/SvPas * C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:114741
immune system phenotype J:114741
Fastm1Cgn/Fastm1Cgn
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Tg(Cd4-cre)1Cwi Fastm1Cgn)
abnormal immune system cell morphology J:114948
abnormal immune system organ morphology J:114948
abnormal thymus involution J:114948
alveolitis J:114948
decreased B cell number J:114948
decreased T cell number J:114948
enlarged spleen J:114948
increased activated T cell number J:114948
increased anti-single stranded DNA antibody level J:114948
increased double-negative T cell number J:114948
increased inflammatory response J:114948
increased memory T cell number J:114948
increased T cell apoptosis J:114948
kidney inflammation J:114948
liver inflammation J:114948
lung inflammation J:114948
lymph node hypoplasia J:114948
spleen hypoplasia J:114948
Fastm1Cgn/Fastm1Cgn
Tg(Lck-cre)I57Jxm/0

(B6.Cg-Fastm1Cgn Tg(Lck-cre)I57Jxm)
lymph node hypoplasia J:114948
Fastm1Cgn/Fastm1Cgn
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Fastm1Cgn Tg(Mx1-cre)1Cgn)
abnormal immune system morphology J:114948
enlarged lymph nodes J:114948
enlarged spleen J:114948
Fastm1Cgn/Fastm1Cgn
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak

(involves: 129S2/SvPas * C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:114741
Fastm1Dlo/Fastm1Dlo
(involves: 129P2/OlaHsd * C57BL/6)
abnormal thymus involution J:90750
enlarged lymph nodes J:31847
enlarged spleen J:31847
increased immunoglobulin level J:31847
Fastm1Osa/Fastm1Osa
(involves: 129P2/OlaHsd * C57BL/6)
abnormal hypersensitivity reaction J:64296, J:32125
abnormal lymph organ size J:64296
abnormal T cell clonal deletion J:32125
enlarged lymph nodes J:64296, J:32125
enlarged spleen J:64296, J:32125
increased anti-double stranded DNA antibody level J:32125
increased anti-single stranded DNA antibody level J:32125
increased autoantibody level J:32125
increased B cell number J:32125
increased IgG1 level J:32125
increased IgG2a level J:32125
increased IgG2b level J:32125
increased IgG3 level J:32125
increased IgG level J:32125
increased leukocyte cell number J:32125
increased lymphocyte cell number J:64296, J:32125
increased susceptibility to parasitic infection J:81397
lymphoid hyperplasia J:64296
Fastm1Osa/Fastm1Osa
Gzmatm1Simn/Gzmatm1Simn
Gzmbtm1Ley/Gzmbtm1Ley

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
increased susceptibility to parasitic infection J:81397
Fastm1Vbo/Fastm1Vbo
Tg(Ins2-cre)25Mgn/0
Tg(Ins2-HA)165Bri/0
Tg(Tcra/Tcrb)1Vbo/0

(Not Specified)
increased susceptibility to autoimmune diabetes J:85985
Fasldel1Hong/Fasldel1Hong
(either: (involves: 129 * BALB/c * C57BL/6) or (involves: 129X1/SvJ * C3H/HeJ * C57BL/6))
abnormal thymus cell ratio J:112563
enlarged lymph nodes J:112563
enlarged spleen J:112563
enlarged thymus J:112563
increased IgG level J:112563
increased IgM level J:112563
Faslgld/Faslgld
(C3H/HeJ-Faslgld/J)
abnormal lymph node morphology J:7306
abnormal T cell differentiation J:12002, J:8267
decreased B cell number J:29572
decreased cytotoxic T cell cytolysis J:17698
enlarged lymph nodes J:7306, J:29572
enlarged spleen J:7306, J:29572
increased anti-double stranded DNA antibody level J:7306
increased anti-nuclear antigen antibody level J:7306, J:29572
increased autoantibody level J:7306
increased IgA level J:7306, J:29572
increased IgG1 level J:7306
increased IgG2a level J:7306
increased IgG2b level J:7306
increased IgG level J:29572
increased IgM level J:7306, J:29572
increased immunoglobulin level J:7306, J:29572
increased leukocyte cell number J:7306
increased lymphocyte cell number J:7306, J:29572
increased neutrophil cell number J:7306
increased T cell number J:29572
interstitial pneumonia J:7306
Faslgld/Faslgld
(B6Smn.C3-Faslgld/J)
abnormal NK cell physiology J:115033
abnormal osteoclast physiology J:127179
brain inflammation J:120427
CNS inflammation J:120427
decreased granulocyte number J:136745
eye inflammation J:136745
increased susceptibility to bacterial infection J:136745
increased susceptibility to Picornaviridae infection J:120427
liver inflammation J:135830
Faslgld/Faslgld
(C3H/HeJ-Faslgld)
abnormal interleukin level J:8267
abnormal T cell morphology J:8267
abnormal T cell physiology J:8267
abnormal T cell proliferation J:8267
Faslgld/Faslgld
(involves: C3H/HeJ * C57BL/6)
dermatitis J:153501
enlarged lymph nodes J:153501
enlarged spleen J:153501
immune system phenotype J:153501
increased anti-nuclear antigen antibody level J:153501
increased circulating tumor necrosis factor level J:153501
increased IgE level J:153501
increased IgG1 level J:153501
increased IgG2a level J:153501
increased IgG2b level J:153501
increased IgG level J:153501
increased susceptibility to systemic lupus erythematosus J:153501
increased T cell number J:153501
Faslgld/Faslgld
(involves: C3H/HeJ)
abnormal osteoclast physiology J:156947
enlarged lymph nodes J:171440
enlarged spleen J:171440
increased spleen weight J:171440
Faslgld/Faslgld
(B6.C3-Faslgld)
abnormal lymph node morphology J:91058
enlarged lymph nodes J:91058
enlarged spleen J:91058
impaired macrophage phagocytosis J:91058
increased anti-nuclear antigen antibody level J:91058
increased autoantibody level J:91058
increased spleen weight J:91058
Faslgld/Faslgld
Ighmtm1Cgn/Ighmtm1Cgn

(involves: 129S2/SvPas * C3H/HeJ * C57BL/6)
immune system phenotype J:119584
Faslm1Btlr/Faslm1Btlr
(C57BL/6J-Faslm1Btlr)
abnormal humoral immune response J:212067
Faslm2Btlr/Faslm2Btlr
(C57BL/6J-Faslm2Btlr)
decreased IgG level J:224659
impaired humoral immune response J:224659
Fasltm1.1Ast/Fasltm1.1Ast
(involves: BALB/cJ * C57BL/6)
decreased cytotoxic T cell cytolysis J:153501
dermatitis J:153501
enlarged lymph nodes J:153501
enlarged spleen J:153501
glomerulonephritis J:153501
immune system phenotype J:153501
increased anti-double stranded DNA antibody level J:153501
increased anti-nuclear antigen antibody level J:153501
increased circulating tumor necrosis factor level J:153501
increased IgA level J:153501
increased IgE level J:153501
increased IgG1 level J:153501
increased IgG2a level J:153501
increased IgG2b level J:153501
increased IgG level J:153501
increased IgM level J:153501
increased immunoglobulin level J:153501
increased susceptibility to systemic lupus erythematosus J:153501
Fasltm1.1Bksa/Fasltm1.1Bksa
(involves: 129)
enlarged lymph nodes J:171440
enlarged spleen J:171440
increased spleen weight J:171440
Fasltm1.1Cgm/Fasltm1.1Cgm
(involves: 129S2/SvPas * C57BL/6 * C57BL/6N)
immune system phenotype J:168406
increased B cell proliferation J:168406
increased germinal center B cell number J:168406
increased IgM level J:168406
increased plasma cell number J:168406
increased T cell proliferation J:168406
Fasltm1.1Lest/Fasltm1.1Lest
(involves: 129 * C57BL/6)
abnormal double-negative T cell morphology J:87990
abnormal lymph node morphology J:87990
autoimmune response J:87990
enlarged lymph nodes J:87990
enlarged spleen J:87990
glomerulonephritis J:87990
increased IgG level J:87990
lymphoid hyperplasia J:87990
Fasltm1.1Lest/Fasltm1.1Lest
(B6.129-Fasltm1.1Lest)
glomerulonephritis J:87990
Fasltm2.1Ast/Fasltm2.1Ast
(involves: BALB/cJ * C57BL/6)
abnormal cytotoxic T cell physiology J:153501
Fastktm1.1Andp/Fastktm1.1Andp
(B6.129S6-Fastktm1.1Andp)
abnormal chemokine secretion J:160443
abnormal neutrophil physiology J:160443
decreased interleukin-6 secretion J:160443
decreased interleukin-23 secretion J:160443
decreased neutrophil cell number J:160443
decreased tumor necrosis factor secretion J:160443
Fastkd2tm1b(EUCOMM)Wtsi/Fastkd2tm1b(EUCOMM)Wtsi
(C57BL/6N-Fastkd2tm1b(EUCOMM)Wtsi/Bay)
decreased spleen weight J:211773
Fat1Gt(KST249)Byg/Fat1Gt(KST249)Byg
Tg(Myl1-lacZ)1Ibdml/0

(involves: 129P2/OlaHsd)
lymphangiectasis J:199157
myositis J:199157
Fat1tm1.2Fhel/Fat1tm1.2Fhel
Tg(Myl1-lacZ)1Ibdml/0

(involves: 129S6/SvEvTac * BALB/cJ * C57BL/6J * SJL)
myositis J:199157
Fbf1tm1a(EUCOMM)Wtsi/Fbf1tm1a(EUCOMM)Wtsi
(C57BL/6N-Fbf1tm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Fblim1tm1.1Chen/Fblim1tm1.1Chen
(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
abnormal osteoclast differentiation J:186501
abnormal osteoclast physiology J:186501
increased osteoclast cell number J:186501
Fbln1Gt(XST011)Byg/Fbln1Gt(XST011)Byg
(involves: 129P2/OlaHsd * C57BL/6)
thymus hypoplasia J:137690
Fbln1tm1Tmpl/Fbln1tm1Tmpl
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
thymus hypoplasia J:137690
Fbn1em1(IMPC)H/Fbn1+
(C57BL/6NTac-Fbn1em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Fbn1tm1Lper/Fbn1+
(involves: 129/Sv * CD-1)
lung inflammation J:167276
Fbn1tm2.1Hcd/Fbn1+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N)
abnormal interleukin secretion J:206074
abnormal T-helper 1 cell morphology J:206074
increased anti-nuclear antigen antibody level J:206074
increased autoantibody level J:206074
increased B cell number J:206074
increased interleukin-9 secretion J:206074
increased interleukin-13 secretion J:206074
increased plasma cell number J:206074
Fbn1tm2Rmz/Fbn1tm2Rmz
(involves: 129S1/Sv * 129X1/SvJ)
aortitis J:54081
lung inflammation J:91815
Fbn1tm3.1Hcd/Fbn1+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N)
abnormal interleukin secretion J:206074
abnormal T-helper 1 cell morphology J:206074
increased anti-nuclear antigen antibody level J:206074
increased autoantibody level J:206074
increased B cell number J:206074
increased interleukin-9 secretion J:206074
increased interleukin-13 secretion J:206074
increased plasma cell number J:206074
Fbn1Tsk/Fbn1+
(B6.Cg-Fbn1Tsk)
abnormal uterine NK cell morphology J:1377
alveolitis J:15018, J:30961, J:6566
increased autoantibody level J:21987, J:14166
increased mast cell number J:8047
increased susceptibility to type IV hypersensitivity reaction J:7185
lung inflammation J:30961, J:6566
Fbn1Tsk/Fbn1+
Il4tm1Nnt/Il4tm1Nnt

(involves: C57BL/6 * C57BL/10 * DBA/2)
decreased interleukin-4 secretion J:57957
Fbn1Tsk/Fbn1+
Il4ratm1Sz/Il4ra+

(involves: BALB/cJ * C57BL/6J * C57BL/10 * DBA/2)
increased autoantibody level J:68448
Fbn1Tsk/Fbn1+
Il4ratm1Sz/Il4ratm1Sz

(involves: BALB/cJ * C57BL/6J * C57BL/10 * DBA/2)
immune system phenotype J:68448
Fbn1Tsk/Fbn1+
KitW/KitW-v

(involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ)
absent mast cells J:24076
Fbn1Tsk/Fbn1+
Stat6tm1Gru/Stat6tm1Gru

(involves: 129S2/SvPas * C57BL/10 * DBA/2)
decreased interleukin-4 secretion J:57957
Fbn1Tsk/Fbn1+
Tgfb1tm1N/Tgfb1+

(involves: 129S/SvEv * C57BL/6J * C57BL/10 * DBA/2)
immune system phenotype J:68448
Fbp2tm2b(EUCOMM)Hmgu/Fbp2+
(C57BL/6N-Fbp2tm2b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Fbrsl1em1(IMPC)Tcp/Fbrsl1em1(IMPC)Tcp
(C57BL/6N-Fbrsl1em1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
small thymus J:211773
Fbxl3em1(IMPC)Ccpcz/Fbxl3em1(IMPC)Ccpcz
(C57BL/6NCrl-Fbxl3em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
decreased spleen weight J:211773
Fbxl4tm1.2Lrsn/Fbxl4tm1.2Lrsn
(involves: C57BL/6N)
liver inflammation J:303084
Fbxl5Gt(OST386421)Lex/Fbxl5+
(involves: 129S5/SvEvBrd * C57BL/6)
increased spleen iron level J:193752
Fbxl5tm2.1Kei/Fbxl5tm2.1Kei
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: C57BL/6 * DBA)
liver inflammation J:176655
Fbxl18tm1b(EUCOMM)Hmgu/Fbxl18tm1b(EUCOMM)Hmgu
(C57BL/6N-Fbxl18tm1b(EUCOMM)Hmgu/Mhzh)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Fbxl19tm1b(EUCOMM)Wtsi/Fbxl19+
(C57BL/6N-Fbxl19tm1b(EUCOMM)Wtsi/Nju)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Fbxo4tm1.1Jadi/Fbxo4+
(Not Specified)
myeloid hyperplasia J:178645
Fbxo4tm1.1Jadi/Fbxo4tm1.1Jadi
(Not Specified)
myeloid hyperplasia J:178645
Fbxo7tm1a(EUCOMM)Hmgu/Fbxo7tm1a(EUCOMM)Hmgu
(involves: C57BL/6N)
increased pro-B cell number J:183053
Fbxo7tm1a(EUCOMM)Wtsi/Fbxo7tm1a(EUCOMM)Wtsi
(C57BL/6N-Fbxo7tm1a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Fbxo7tm1a(EUCOMM)Wtsi/Fbxo7tm1a(EUCOMM)Wtsi
(involves: C57BL/6N)
abnormal effector T cell number J:272313
abnormal T cell differentiation J:272313
decreased CD4-positive, alpha-beta T cell number J:272313
decreased CD8-positive, alpha-beta T cell number J:272313
decreased T cell number J:272313
enlarged spleen J:272313
increased activated T cell number J:272313
increased double-negative T cell number J:272313
increased effector memory CD4-positive, alpha-beta T cell number J:272313
increased effector memory CD8-positive, alpha-beta T cell number J:272313
increased memory T cell number J:272313
increased spleen weight J:272313
increased susceptibility to bacterial infection J:272313
increased susceptibility to bacterial infection induced morbidity/mortality J:272313
thymus atrophy J:272313
thymus hypoplasia J:272313
Fbxo7tm1c(EUCOMM)Wtsi/Fbxo7tm1c(EUCOMM)Wtsi
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6J * C57BL/6N)
decreased CD8-positive, alpha-beta T cell number J:272313
decreased T cell number J:272313
immune system phenotype J:272313
Fbxo9tm1b(EUCOMM)Hmgu/Fbxo9tm1b(EUCOMM)Hmgu
(C57BL/6N-Fbxo9tm1b(EUCOMM)Hmgu/Tcp)
increased basophil cell number J:211773
Fbxo10tm1b(KOMP)Wtsi/Fbxo10tm1b(KOMP)Wtsi
(C57BL/6N-Fbxo10tm1b(KOMP)Wtsi/Nju)
decreased neutrophil cell number J:211773
Fbxo11Jf/Fbxo11+
(involves: BALB/cAnNCrl * C3H/HeN)
abnormal cytokine secretion J:85263
increased susceptibility to otitis media J:85263
Fbxo11Jf/Fbxo11+
(involves: BALB/cAnNCrl * C3H/HeN * C57BL/6J)
increased susceptibility to otitis media J:114851
Fbxo11Jf/Fbxo11+
(involves: BALB/cAnNCrl)
increased susceptibility to otitis media J:250208
Fbxo11Jf/Fbxo11Mutt
(involves: BALB/c * C3H/HeN)
increased susceptibility to otitis media J:114851
Fbxo21em1Smbk/Fbxo21em1Smbk
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(B6.Cg-Fbxo21em1Smbk Commd10Tg(Vav1-icre)A2Kio)
decreased spleen weight J:333469
increased T cell number J:333469
Fbxo25em1(IMPC)Ccpcz/Fbxo25em1(IMPC)Ccpcz
(C57BL/6N-Fbxo25em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fbxo28em1(IMPC)Mhzh/Fbxo28+
(C57BL/6N-Fbxo28em1(IMPC)Mhzh/Mhzh)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Fbxo36tm1b(KOMP)Wtsi/Fbxo36tm1b(KOMP)Wtsi
(C57BL/6N-Fbxo36tm1b(KOMP)Wtsi/Nju)
decreased monocyte cell number J:211773
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Fbxw2tm1b(EUCOMM)Hmgu/Fbxw2tm1b(EUCOMM)Hmgu
(C57BL/6N-Fbxw2tm1b(EUCOMM)Hmgu/Nju)
increased basophil cell number J:211773
Fbxw7tm1Iaai/Fbxw7tm1Iaai
Tg(Lck-cre)1Cwi/0

(involves: 129/Sv * C57BL/6)
immune system phenotype J:137138
Fbxw7tm1Iaai/Fbxw7tm1Iaai
Tg(Mx1-cre)1Cgn/0

(involves: 129/Sv * C57BL/6 * CBA)
abnormal T cell differentiation J:137138
decreased double-negative T cell number J:137138
thymus hypoplasia J:137138
Fbxw7tm1Iaai/Fbxw7tm1Iaai
Tg(Mx1-cre)1Cgn/0

(involves: 129 * C57BL/6 * CBA)
abnormal T cell differentiation J:200006
Fbxw7tm1Kei/Fbxw7tm1Kei
Myctm2Fwa/Myctm2Fwa
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2)
immune system phenotype J:128523
Fbxw7tm1Kei/Fbxw7tm1Kei
Rbpjtm1Hon/Rbpjtm1Hon
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
increased double-positive T cell number J:128523
Fbxw7tm1Kei/Fbxw7tm1Kei
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6)
increased double-positive T cell number J:128523
Fbxw7tm1Kei/Fbxw7tm1Kei
Tg(Lck-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell activation J:128523
arrested T cell differentiation J:128523
decreased single-positive T cell number J:128523
enlarged thymus J:128523
increased double-positive T cell number J:128523
increased T cell apoptosis J:128523
Fbxw7tm1Kei/Fbxw7tm1Kei
Trp53tm1Tyj/Trp53tm1Tyj
Tg(Lck-cre)1Cwi/?

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
immune system phenotype J:128523
Fbxw7tm2Iaai/Fbxw7+
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
immune system phenotype J:200006
Fbxw8tm1b(EUCOMM)Hmgu/Fbxw8+
(C57BL/6N-Fbxw8tm1b(EUCOMM)Hmgu/Nju)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
Fbxw9tm1a(EUCOMM)Wtsi/Fbxw9+
(C57BL/6N-Fbxw9tm1a(EUCOMM)Wtsi/Bay)
absent spleen J:211773
Fbxw9tm1a(EUCOMM)Wtsi/Fbxw9tm1a(EUCOMM)Wtsi
(C57BL/6N-Fbxw9tm1a(EUCOMM)Wtsi/Bay)
absent lymph nodes J:211773
Fbxw9tm1b(EUCOMM)Wtsi/Fbxw9tm1b(EUCOMM)Wtsi
(C57BL/6N-Fbxw9tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Fbxw10em1(IMPC)Tcp/Fbxw10em1(IMPC)Tcp
(C57BL/6N-Fbxw10em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Fbxw16em1(IMPC)Ccpcz/Fbxw16+
(C57BL/6N-Fbxw16em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
small thymus J:211773
Fbxw18em1(IMPC)Ccpcz/Fbxw18+
(C57BL/6N-Fbxw18em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
small spleen J:211773
Fbxw20em1(IMPC)Ccpcz/Fbxw20em1(IMPC)Ccpcz
(C57BL/6N-Fbxw20em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fbxw25em1(IMPC)Ccpcz/Fbxw25em1(IMPC)Ccpcz
(C57BL/6NCrl-Fbxw25em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Fbxw26tm1b(KOMP)Wtsi/Fbxw26tm1b(KOMP)Wtsi
(C57BL/6N-Fbxw26tm1b(KOMP)Wtsi/Wtsi)
decreased memory-marker NK cell number J:211773
increased KLRG1-positive NK cell number J:211773
increased NK cell number J:211773
Fcamrtm1Shib/Fcamrtm1Shib
(involves: 129P2/OlaHsd * C57BL/6)
abnormal follicular dendritic cell antigen presentation J:150824
abnormal marginal zone B cell physiology J:150824
abnormal memory B cell differentiation J:150824
abnormal somatic hypermutation frequency J:150824
abnormal spleen germinal center morphology J:150824
increased spleen germinal center number J:150824
increased spleen germinal center size J:150824
Fcamrtm2Shib/Fcamrtm2Shib
(BALB/c-Fcamrtm2Shib)
abnormal follicular dendritic cell antigen presentation J:150824
abnormal marginal zone B cell physiology J:150824
increased spleen germinal center number J:150824
increased spleen germinal center size J:150824
Fcer1atm1Ftl/Fcer1atm1Ftl
(CBy.129S2-Fcer1atm1Ftl)
abnormal humoral immune response J:120702
abnormal mast cell physiology J:120702
decreased circulating interleukin-4 level J:120702
decreased eosinophil cell number J:120702
Fcer1atm1Knt/Fcer1atm1Knt
(either: (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * DBA/2))
abnormal mast cell physiology J:39250
decreased susceptibility to type I hypersensitivity reaction J:113572, J:39250
Fcer1atm1Knt/Fcer1atm1Knt
(involves: 129 * BALB/c)
abnormal mast cell physiology J:78659
increased susceptibility to type I hypersensitivity reaction J:78659
Fcer1atm1Knt/Fcer1atm1Knt
Fcer2atm1Max/Fcer2atm1Max

(B6.Cg-Fcer1atm1Knt Fcer2atm1Max)
abnormal mast cell physiology J:144620
Fcer1atm1Knt/Fcer1atm1Knt
Fcer2atm1Max/Fcer2atm1Max
Fcgr1tm1Jsv/Fcgr1tm1Jsv
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Fcgr3tm1Jsv/Fcgr3tm1Jsv

(B6.Cg-Fcgr2btm1Ttk Fcgr3tm1Jsv Fcer1atm1Knt Fcgr1tm1Jsv Fcer2atm1Max)
abnormal macrophage physiology J:144620
abnormal mast cell physiology J:144620
increased susceptibility to type I hypersensitivity reaction J:144620
Fcer1atm1Knt/Fcer1atm1Knt
Tg(FCER1A)1Bhk/?

(B6.129-Fcer1atm1Knt Tg(FCER1A)1Bhk)
abnormal macrophage physiology J:144620
increased tumor necrosis factor secretion J:144620
Fcer1atm1Knt/Fcer1atm1Knt
Tg(SV40/HTLV-FCER1A)1Bhk/0

(either: (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * DBA/2))
abnormal type I hypersensitivity reaction J:113572
Fcer1gtm1Rav/Fcer1gtm1Rav
(involves: 129P2/OlaHsd * C57BL/6)
abnormal dendritic cell antigen presentation J:83995
abnormal immune cell physiology J:39248
abnormal immunoglobulin level J:78659
abnormal mast cell physiology J:39248
abnormal NK cell physiology J:39248
decreased susceptibility to experimental autoimmune encephalomyelitis J:126520
decreased susceptibility to type I hypersensitivity reaction J:78659, J:39248
immune system phenotype J:28282
impaired macrophage phagocytosis J:39248
increased IgE level J:78659
Fcer1gtm1Rav/Fcer1gtm1Rav
(B6.129P2-Fcer1gtm1Rav)
decreased interleukin-1 beta secretion J:160680
decreased interleukin-6 secretion J:160680
decreased interleukin-10 secretion J:160680
decreased interleukin-12b secretion J:160680
decreased interleukin-23 secretion J:160680
decreased tumor necrosis factor secretion J:160680
Fcer1gtm1Rav/Fcer1gtm1Rav
(involves: 129P2/OlaHsd)
increased susceptibility to parasitic infection J:163761
Fcer1gtm1Rav/Fcer1gtm1Rav
Del(7Tyrobp-Hcst)1Ttk/Del(7Tyrobp-Hcst)1Ttk

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6)
abnormal osteoclast physiology J:147155
Fcer1gtm1Rav/Fcer1gtm1Rav
Hexbtm1Rlp/Hexbtm1Rlp

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
increased immunoglobulin level J:87617
Fcer1gtm1Rav/Fcer1gtm1Rav
Tg(Ins2-TFRC/OVA)296Wehi/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased susceptibility to autoimmune diabetes J:122114
decreased T cell proliferation J:122114
Fcer1gtm1Rav/Fcer1gtm1Rav
Tyrobptm1.1Viv/Tyrobptm1.1Viv

(involves: 129P2/OlaHsd * C57BL/6)
decreased interferon-gamma secretion J:100668
decreased uterine NK cell number J:100668
Fcer1gtm1Rav/Fcer1gtm1Rav
Tyrobptm1Lll/Tyrobptm1Lll

(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:89583
Fcer1gtm1Rav/Fcer1gtm1Rav
Tyrobptm1Lll/Tyrobptm1Lll

(involves: 129P2/OlaHsd)
abnormal osteoclast physiology J:147155
Fcer1gtm1Tks/Fcer1gtm1Tks
(involves: C57BL/6)
abnormal antigen presentation J:112160
abnormal CD4-positive, alpha-beta T cell physiology J:112160
abnormal chemokine secretion J:141143
abnormal cytokine level J:258645
abnormal macrophage physiology J:141143
abnormal NK cell physiology J:111365
abnormal NK T cell physiology J:111365
decreased IgG1 level J:112160
decreased IgG2a level J:112160
decreased IgG2b level J:112160
decreased IgG3 level J:112160
decreased IgG level J:112160
decreased inflammatory response J:50023
decreased interferon-gamma secretion J:111365, J:112160
decreased interleukin-2 secretion J:112160
decreased susceptibility to type IV hypersensitivity reaction J:112160
decreased T cell proliferation J:112160
impaired macrophage phagocytosis J:50023
impaired natural killer cell mediated cytotoxicity J:111365
Fcer1gtm1Tks/Fcer1gtm1Tks
(C57BL/6-Fcer1gtm1Tks)
decreased susceptibility to autoimmune hemolytic anemia J:145432
Fcer1gtm1Tks/Fcer1gtm1Tks
(involves: C57BL/6J)
abnormal chemokine secretion J:203159
abnormal interferon-gamma secretion J:203159
abnormal interleukin-17 secretion J:203159
decreased dendritic cell number J:203159
decreased tumor necrosis factor secretion J:203159
Fcer2aHie/Fcer2aHie
(NZB)
increased IgE level J:93999
Fcer2atm1Kik/Fcer2atm1Kik
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:129296
abnormal humoral immune response J:19437
abnormal immune system physiology J:129296
increased immunoglobulin level J:129296
Fcer2atm1Max/Fcer2atm1Max
(involves: C57BL/6)
abnormal macrophage chemotaxis J:57738
decreased IgG1 level J:18952
decreased IgG2b level J:18952
impaired eosinophil recruitment J:57738
increased IgE level J:57738, J:18952, J:107857
increased IgM level J:18952
increased susceptibility to type I hypersensitivity reaction J:57738
Fcer2atm1Max/Fcer2atm1Max
Ighg1tm1.1Pyu/Ighg1+

(involves: 129 * BALB/cJ * C57BL/6 * C57BL/6J)
decreased IgG1 level J:198154
decreased IgG2c level J:198154
decreased IgG level J:198154
increased IgE level J:198154
increased IgG2a level J:198154
increased susceptibility to type I hypersensitivity reaction J:198154
Fcer2atm1Max/Fcer2atm1Max
Ighg1tm1.1Pyu/Ighg1tm1.1Pyu

(involves: 129 * BALB/cJ * C57BL/6 * C57BL/6J)
abnormal immunoglobulin level J:198154
decreased IgG2c level J:198154
decreased IgG level J:198154
increased IgE level J:198154
increased IgG2a level J:198154
increased susceptibility to type I hypersensitivity reaction J:198154
Fcer2atm1Putt/Fcer2a+
(involves: 129S/SvEv * C57BL/6)
increased IgE level J:69547
Fcer2atm1Putt/Fcer2atm1Putt
(involves: 129S/SvEv * C57BL/6)
abnormal B cell proliferation J:69547
Fcgr1tm1Hoga/Fcgr1tm1Hoga
(involves: 129S1/Sv * 129X1/SvJ)
abnormal cell-mediated immunity J:86281
abnormal macrophage antigen presentation J:86281
decreased inflammatory response J:86281
impaired macrophage phagocytosis J:86281
increased IgG level J:86281
Fcgr1tm1Jgjw/Fcgr1tm1Jgjw
(involves: 129 * C57BL/6)
abnormal dendritic cell antigen presentation J:112436
abnormal dendritic cell differentiation J:112436
Fcgr1tm1Jsv/Fcgr1tm1Jsv
(involves: 129P2/OlaHsd * BALB/c)
abnormal dendritic cell antigen presentation J:83995
abnormal macrophage physiology J:83995
abnormal type I hypersensitivity reaction J:83995
decreased susceptibility to autoimmune hemolytic anemia J:83995
decreased susceptibility to induced arthritis J:83995
increased susceptibility to bacterial infection J:83995
Fcgr1tm1Jsv/Fcgr1tm1Jsv
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Fcgr3tm1Jsv/Fcgr3tm1Jsv

(involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6)
impaired macrophage phagocytosis J:83995
Fcgr2btm1.2Jsv/Fcgr2b+
X/Yaa

(involves: C57BL/6 * FVB/N * SB/Le)
enlarged spleen J:179175
increased anti-chromatin antibody level J:179175
increased anti-double stranded DNA antibody level J:179175
increased monocyte cell number J:179175
increased susceptibility to systemic lupus erythematosus J:179175
Fcgr2btm1.2Jsv/Fcgr2btm1.2Jsv
Sle16C57BL/6/Sle16C57BL/6

(involves: C57BL/6 * FVB/N)
abnormal adaptive immunity J:179175
immune system phenotype J:179175
increased immunoglobulin level J:179175
increased susceptibility to induced arthritis J:179175
kidney inflammation J:179175
Fcgr2btm1Kgcs/Fcgr2b+
(involves: C57BL/6)
decreased B cell apoptosis J:190890
increased anti-chromatin antibody level J:190890
increased anti-double stranded DNA antibody level J:190890
increased germinal center B cell number J:190890
increased IgG1 level J:190890
increased IgG3 level J:190890
increased IgM level J:190890
increased susceptibility to induced arthritis J:190890
Fcgr2btm1Ttk/Fcgr2b+
X/Yaa

(involves: 129S4/SvJae * C57BL/6 * SB/Le)
increased monocyte cell number J:129409
Fcgr2btm1Ttk/Fcgr2btm1.2Jsv
Sle21129P2/Ola/Sle21C57BL/6

(involves: 129P2/Ola * 129S4/SvJae * C57BL/6 * FVB/N)
enlarged spleen J:179175
increased anti-chromatin antibody level J:179175
increased anti-double stranded DNA antibody level J:179175
increased anti-histone antibody level J:179175
increased anti-single stranded DNA antibody level J:179175
increased spleen weight J:179175
increased susceptibility to systemic lupus erythematosus J:179175
Fcgr2btm1Ttk/Fcgr2btm1Ttk
(involves: 129S4/SvJae)
abnormal mast cell physiology J:31133
increased IgA level J:31133
increased IgG1 level J:31133
increased IgG2a level J:31133
increased IgG2b level J:31133
increased IgG3 level J:31133
increased IgG level J:31133
increased IgM level J:31133
increased susceptibility to type I hypersensitivity reaction J:31133
Fcgr2btm1Ttk/Fcgr2btm1Ttk
(C.129S4-Fcgr2btm1Ttk)
decreased susceptibility to parasitic infection J:120905
Fcgr2btm1Ttk/Fcgr2btm1Ttk
(B6.129S4-Fcgr2btm1Ttk)
abnormal hypersensitivity reaction J:64152
enlarged lymph nodes J:64152
enlarged spleen J:64152
glomerulonephritis J:64152
increased immunoglobulin level J:64152
increased inflammatory response J:64152
kidney inflammation J:64152
liver inflammation J:64152
lung inflammation J:64152
pancreas inflammation J:64152
salivary gland inflammation J:64152
Fcgr2btm1Ttk/Fcgr2btm1Ttk
(Not Specified)
increased susceptibility to induced arthritis J:106191
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Il17atm1Yiw/Il17a+

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
glomerulonephritis J:191090
increased plasma cell number J:191090
increased spleen germinal center number J:191090
kidney inflammation J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Il17atm1Yiw/Il17atm1Yiw

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
decreased susceptibility to systemic lupus erythematosus J:191090
increased anti-double stranded DNA antibody level J:191090
increased anti-nuclear antigen antibody level J:191090
increased double-negative T cell number J:191090
increased plasma cell number J:191090
increased spleen germinal center number J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Pdcd1tm1Hon/Pdcd1tm1Hon

(involves: 129S2/SvPas * 129S4/SvJae * BALB/c)
abnormal cytokine level J:207275
abnormal urine cytokine level J:207275
increased autoantibody level J:207275
urinary bladder inflammation J:207275
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Sle21129P2/Ola/Sle21129P2/Ola

(B6.129S4-Fcgr2btm1Ttk)
abnormal adaptive immunity J:179175
enlarged spleen J:179175
increased anti-chromatin antibody level J:179175
increased anti-double stranded DNA antibody level J:179175
increased anti-histone antibody level J:179175
increased anti-single stranded DNA antibody level J:179175
increased autoantibody level J:179175
increased IgG2a level J:179175
increased immunoglobulin level J:179175
increased spleen weight J:179175
increased susceptibility to induced arthritis J:179175
increased susceptibility to systemic lupus erythematosus J:179175
kidney inflammation J:179175
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Tg(Ins2-TFRC/OVA)296Wehi/0

(involves: 129S4/SvJae * C57BL/6)
increased susceptibility to autoimmune diabetes J:122114
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Tlr7tm1Flv/Y
X/Yaa

(B6.Cg-Fcgr2btm1Ttk Tlr7tm1Flv Yaa)
abnormal splenocyte physiology J:127600
autoimmune response J:127600
enlarged spleen J:127600
increased anti-nuclear antigen antibody level J:127600
increased susceptibility to systemic lupus erythematosus J:127600
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm1Sbn/Traf3ip2+

(involves: 129 * 129S4/SvJae * C57BL/6)
abnormal neutrophil morphology J:191090
abnormal T cell morphology J:191090
increased anti-double stranded DNA antibody level J:191090
increased anti-nuclear antigen antibody level J:191090
increased autoantibody level J:191090
increased double-negative T cell number J:191090
increased IgG level J:191090
increased memory T cell number J:191090
increased monocyte cell number J:191090
increased myeloid dendritic cell number J:191090
increased neutrophil cell number J:191090
increased plasma cell number J:191090
increased plasmacytoid dendritic cell number J:191090
increased single-positive T cell number J:191090
increased spleen germinal center number J:191090
increased susceptibility to systemic lupus erythematosus J:191090
kidney inflammation J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm1Sbn/Traf3ip2tm1Sbn

(involves: 129 * 129S4/SvJae * C57BL/6)
abnormal T cell morphology J:191090
decreased susceptibility to systemic lupus erythematosus J:191090
increased anti-double stranded DNA antibody level J:191090
increased anti-nuclear antigen antibody level J:191090
increased autoantibody level J:191090
increased double-negative T cell number J:191090
increased IgG level J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm2Sbn/Traf3ip2+

(involves: 129S4/SvJae * BALB/c * C57BL/6)
enlarged spleen J:191090
increased germinal center B cell number J:191090
increased plasma cell number J:191090
increased spleen weight J:191090
spleen hyperplasia J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm2Sbn/Traf3ip2tm2Sbn
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S4/SvJae * BALB/c * C57BL/6)
glomerulonephritis J:191090
increased germinal center B cell number J:191090
increased plasma cell number J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
X/Yaa

(B6.Cg-Fcgr2btm1Ttk Yaa)
autoimmune response J:127600
enlarged spleen J:127600
increased anti-nuclear antigen antibody level J:127600
increased susceptibility to systemic lupus erythematosus J:127600
Fcgr3tm1Jsv/Fcgr3tm1Jsv
(involves: 129P2/OlaHsd * C57BL/6)
abnormal dendritic cell antigen presentation J:83995
abnormal type I hypersensitivity reaction J:83995
decreased mast cell degranulation J:35057
decreased susceptibility to autoimmune hemolytic anemia J:83995
decreased susceptibility to type II hypersensitivity reaction J:35057
impaired macrophage phagocytosis J:35057
impaired natural killer cell mediated cytotoxicity J:35057
Fcgr3tm1Jsv/Fcgr3tm1Jsv
(B6.129P2-Fcgr3tm1Jsv/J)
abnormal leukocyte cell number J:78297
abnormal neutrophil physiology J:78297
decreased susceptibility to experimental autoimmune encephalomyelitis J:126520
decreased susceptibility to induced arthritis J:106191
impaired neutrophil recruitment J:78297
increased neutrophil cell number J:78297
Fcgr3tm1Jsv/Fcgr3tm1Jsv
Sle21129P2/Ola/Sle21129P2/Ola

(B6.129P2-Fcgr3tm1Jsv)
enlarged spleen J:179175
increased activated T cell number J:179175
increased anti-chromatin antibody level J:179175
increased anti-double stranded DNA antibody level J:179175
increased anti-histone antibody level J:179175
increased anti-single stranded DNA antibody level J:179175
increased B cell number J:179175
increased spleen weight J:179175
Fcgr3tm1Ttk/Fcgr3tm1Ttk
(involves: 129X1/SvJ)
decreased susceptibility to type I hypersensitivity reaction J:107371
Fcgr4tm1.1Rav/Fcgr4tm1.1Rav
(involves: C57BL/6)
decreased susceptibility to induced arthritis J:167375
immune system phenotype J:167375
Fcgr4tm1Rav/Fcgr4tm1Rav
Tg(Ctsk-cre)1Rda/0

(involves: C57BL/6)
arthritis J:197378
decreased osteoclast cell number J:197378
Fcgrttm1Dcr/Fcgrttm1Dcr
(either: 129 or (involves: 129 * C57BL/6))
decreased IgG level J:94189
Fcgrttm1Dcr/Fcgrttm1Dcr
(B6.129X1-Fcgrttm1Dcr/DcrJ)
decreased IgG level J:110885
Fcgrttm1Dcr/Fcgrttm1Dcr
Tg(CAG-FCGRT)276Dcr/0

(involves: 129X1/SvJ * C57BL/6 * C57BL/6J)
immune system phenotype J:110885
Fcgrttm1Esw/Fcgrttm1Esw
Tg(Tek-cre)1Ywa/0

(B6.Cg-Tg(Tek-cre)1Ywa Fcgrttm1Esw)
abnormal humoral immune response J:146640
decreased IgG1 level J:146640
Fcmrtm1.2Khl/Fcmrtm1.2Khl
(involves: C57BL/6)
abnormal granulocyte physiology J:194323
decreased B cell number J:174871
immune system phenotype J:174871
increased T cell apoptosis J:174871
Fcmrtm1Mak/Fcmrtm1Mak
(B6.129S2-Fcmrtm1Mak)
abnormal cytokine secretion J:194323
abnormal granulocyte physiology J:194323
decreased interleukin-6 secretion J:194323
decreased susceptibility to bacterial infection induced morbidity/mortality J:194323
decreased tumor necrosis factor secretion J:194323
impaired granulocyte bactericidal activity J:194323
increased susceptibility to bacterial infection J:194323
increased susceptibility to bacterial infection induced morbidity/mortality J:194323
Fcmrtm1Ohno/Fcmrtm1Ohno
(B6.129-Fcmrtm1Ohno)
abnormal B cell morphology J:190117
abnormal immunoglobulin level J:190117
abnormal response to infection J:190117
decreased IgG1 level J:190117
decreased IgM level J:190117
decreased marginal zone B cell number J:190117
increased anti-chromatin antibody level J:190117
increased anti-double stranded DNA antibody level J:190117
increased B-1 B cell number J:190117
increased IgG3 level J:190117
increased IgM level J:190117
increased T cell number J:190117
Fcnatm1Tefu/Fcnatm1Tefu
(involves: 129S4/SvJae)
immune system phenotype J:177350
Fcnatm1Tefu/Fcnatm1Tefu
(B6.129-Fcnatm1Tefu)
impaired lectin complement pathway J:190858
increased susceptibility to bacterial infection J:190858
increased susceptibility to bacterial infection induced morbidity/mortality J:190858
Fcnatm1Tefu/Fcnatm1Tefu
Fcnbtm1Tefu/Fcnbtm1Tefu

(B6.129-Fcnatm1Tefu Fcnbtm1Yend)
impaired lectin complement pathway J:190858
increased susceptibility to bacterial infection J:190858
increased susceptibility to bacterial infection induced morbidity/mortality J:190858
Fcnatm1Tefu/Fcnatm1Tefu
Mbl1tm1Kata/Mbl1tm1Kata
Mbl2tm1Kata/Mbl2tm1Kata

(involves: 129S4/SvJae)
immune system phenotype J:177350
Fcnbtm1Tefu/Fcnbtm1Tefu
(B6.129-Fcnbtm1Yend)
increased susceptibility to bacterial infection J:190858
increased susceptibility to bacterial infection induced morbidity/mortality J:190858
Fcrl2tm1Lex/Fcrl2tm1Lex
(B6;129S5-Fcrl2tm1Lex/Mmucd)
decreased CD8-positive, alpha-beta T cell number J:171883
Fcrlatm1.1Cln/Fcrlatm1.1Cln
(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:163261
immune system phenotype J:163261
increased IgG1 level J:163261
Fcrlatm1b(KOMP)Wtsi/Fcrlatm1b(KOMP)Wtsi
(C57BL/6N-Fcrlatm1b(KOMP)Wtsi/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Fcrlbtm1Pdb/Fcrlbtm1Pdb
(B6.129-Fcrlbtm1Pdb)
increased anti-nuclear antigen antibody level J:165408
increased IgG1 level J:165408
Fdx2em1(IMPC)Rbrc/Fdx2em1(IMPC)Rbrc
(C57BL/6NJcl-Fdx2em1(IMPC)Rbrc/Rbrc)
abnormal large unstained cell number J:211773
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Fdxrtm1Xch/Fdxr+
(B6.Cg-Fdxrtm1Xch)
chronic liver inflammation J:244082
Fechm1Pas/Fechm1Pas
(involves: 129/Sv * BALB/c)
increased spleen weight J:2021
Fechm1Pas/Fechtm1.1(FECH*)Emi
(involves: 129 * BALB/cJ * C57BL/6J)
decreased eosinophil cell number J:239515
enlarged spleen J:239515
Fem1atm1Seno/Fem1atm1Seno
(C57BL/6-Fem1atm1Seno)
increased susceptibility to colitis induced morbidity/mortality J:228893
increased susceptibility to induced colitis J:228893
Fen1tm1Bhsh/Fen1tm1Bhsh
(involves: 129S1/Sv)
pale spleen J:121378
Fen1tm1Rak/Fen1+
(involves: 129/Sv * C57BL/6 * SJL/J)
thymus atrophy J:77962
Fen1tm2Klng/Fen1tm2Klng
(involves: 129X1/SvJ * C57BL/6)
abnormal spleen B cell follicle morphology J:138901
abnormal spleen marginal zone morphology J:138901
enlarged spleen J:138901
immune system phenotype J:138901
increased spleen B cell follicle number J:138901
increased spleen B cell follicle size J:138901
lymphoid hyperplasia J:138901
Fen1tm3.1Bhsh/Fen1+
(Not Specified)
chronic inflammation J:231218
enlarged spleen J:231218
glomerulonephritis J:231218
increased anti-double stranded DNA antibody level J:231218
increased anti-nuclear antigen antibody level J:231218
increased plasma cell number J:231218
increased susceptibility to autoimmune disorder J:231218
interstitial pneumonia J:231218
lung inflammation J:231218
lymphoid hyperplasia J:231218
Fen1tm3.1Bhsh/Fen1tm3.1Bhsh
(Not Specified)
chronic inflammation J:231218
enlarged spleen J:231218
glomerulonephritis J:231218
increased anti-double stranded DNA antibody level J:231218
increased anti-nuclear antigen antibody level J:231218
increased plasma cell number J:231218
increased susceptibility to autoimmune disorder J:231218
interstitial pneumonia J:231218
lung inflammation J:231218
lymphoid hyperplasia J:231218
Ferem1(IMPC)Tcp/Fer+
(C57BL/6N-Ferem1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
increased spleen weight J:211773
Ferem1(IMPC)Tcp/Ferem1(IMPC)Tcp
(C57BL/6N-Ferem1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
Fermt1tm1Ref/Fermt1tm1Ref
(involves: 129S1/Sv * 129X1/SvJ)
ileum inflammation J:142913
large intestinal inflammation J:142913
Fermt3tm1.1Efp/Fermt3tm1.1Efp
(involves: C57BL/6)
increased leukocyte cell number J:227094
Fermt3tm2.1Ref/Fermt3tm2.1Ref
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal effector T cell morphology J:203436
abnormal T cell physiology J:203436
Festm1Mcs/Festm1Mcs
(involves: 129X1/SvJ)
abnormal leukocyte cell number J:64748
abnormal macrophage physiology J:64748
conjunctivitis J:64748
decreased B cell number J:64748
increased granulocyte number J:64748
increased monocyte cell number J:64748
increased neutrophil cell number J:64748
increased susceptibility to bacterial infection J:64748
thymus hypoplasia J:64748
Festm2Pag/Festm2Pag
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal myelopoiesis J:98590
decreased B cell number J:98590
increased pre-B cell number J:98590
increased pro-B cell number J:98590
increased susceptibility to endotoxin shock J:98590
Ffar2tm1Dgen/Ffar2tm1Dgen
(involves: C57BL/6)
abnormal granulocyte physiology J:153951
abnormal neutrophil physiology J:153951
impaired neutrophil chemotaxis J:153951
impaired neutrophil phagocytosis J:153951
increased susceptibility to induced arthritis J:153951
increased susceptibility to induced colitis J:153951
increased T cell number J:153951
lung inflammation J:153951
Ffar2tm2Lex/Ffar2tm2Lex
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal cytokine level J:157383
abnormal inflammatory response J:157383
abnormal neutrophil morphology J:157383
decreased circulating tumor necrosis factor level J:157383
decreased susceptibility to induced colitis J:157383
decreased tumor necrosis factor secretion J:157383
impaired neutrophil chemotaxis J:157383
increased circulating tumor necrosis factor level J:157383
large intestinal inflammation J:157383
sepsis J:157383
Fgatm1Jld/Fgatm1Jld
(involves: 129P2/OlaHsd * CF-1)
decreased circulating fibrinogen level J:28436
Fgatm1Jld/Fgatm1Jld
(B6.129P2-Fgatm1Jld)
decreased circulating fibrinogen level J:28436
Fgatm1Jld/Fgatm1Jld
Plgtm1Jld/Plgtm1Jld

(involves: 129P2/OlaHsd * Black Swiss * CF-1)
immune system phenotype J:36591
Fgd1em1(IMPC)Tcp/Fgd1+
(C57BL/6NCrl-Fgd1em1(IMPC)Tcp/Tcp)
enlarged thymus J:211773
Fgd3em1(IMPC)Ccpcz/Fgd3em1(IMPC)Ccpcz
(C57BL/6N-Fgd3em1(IMPC)Ccpcz/Ccpcz)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
Fgd5em1(IMPC)Mbp/Fgd5+
(C57BL/6NCrl-Fgd5em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Fgf3tm4b(EUCOMM)Hmgu/Fgf3+
(C57BL/6N-Fgf3tm4b(EUCOMM)Hmgu/Bay)
enlarged lymph nodes J:211773
Fgf7tm1Efu/Fgf7tm1Efu
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immune system physiology J:129368
abnormal response to transplant J:129368
immune system phenotype J:129368
spleen hypoplasia J:129368
Fgf8tm1.3Mrt/Fgf8tm1.4Mrt
Tg(Tbx1-cre)1Joe/0

(involves: 129P2/OlaHsd)
abnormal thymus morphology J:88814
small thymus J:88814
Fgf8tm1.4Mrt/Fgf8+
Tbx1tm1Bld/Tbx1+

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * ICR)
thymus hypoplasia J:78686
Fgf8tm1Mrc/Fgf8tm1Moon
Hoxa3tm1(cre)Moon/Hoxa3+

(involves: 129/Sv * C57BL/6)
ectopic thymus J:87304
thymus hypoplasia J:87304
Fgf8tm1Mrc/Fgf8tm2Mrc
Hoxa3tm1(cre)Moon/Hoxa3+

(involves: 129/Sv * C57BL/6)
ectopic thymus J:87304
thymus hypoplasia J:87304
Fgf10tm1b(EUCOMM)Wtsi/Fgf10+
(C57BL/6N-Fgf10tm1b(EUCOMM)Wtsi/H)
decreased leukocyte cell number J:211773
Fgf10tm1Ska/Fgf10tm1Ska
(involves: C57BL/6 * CBA)
small thymus J:114183
Fgf14em1(IMPC)Ccpcz/Fgf14em1(IMPC)Ccpcz
(C57BL/6N-Fgf14em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
Fgf23tm1Blan/Fgf23tm1Blan
(involves: 129/Sv * C57BL/6)
small spleen J:121006
Fgf23tm1Tyam/Fgf23tm1Tyam
(involves: C57BL/6 * CBA)
decreased lymphocyte cell number J:88172
spleen hypoplasia J:88172
thymus atrophy J:88172
Fgfbp3tm1.1(KOMP)Wtsi/Fgfbp3tm1.1(KOMP)Wtsi
(C57BL/6N-Fgfbp3tm1.1(KOMP)Wtsi/Ucd)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Fgfr1Hspy/Fgfr1+
(C3HeB/FeJ-Hspy)
increased susceptibility to otitis media J:95895
Fgfr1tm1Upir/Fgfr1tm1Upir
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(KRT5-cre)5132Jlj/0

(involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J)
abnormal chemokine level J:221184
abnormal mast cell morphology J:221184
dermatitis J:221184
increased IgE level J:158802
increased IgG1 level J:158802
increased IgG2a level J:158802
increased mast cell number J:221184
skin inflammation J:158802, J:221184
Fgfr2tm1Dor/Fgfr2tm1.1Dor
Twist2tm1(cre)Dor/Twist2+

(involves: 129X1/SvJ)
abnormal osteoclast differentiation J:90391
Fgfr2tm1Dsn/Fgfr2tm1Dsn
Tg(KRT5-cre)5132Jlj/0

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
adipose tissue inflammation J:119723
increased gamma-delta T cell number J:119723
skin inflammation J:119723
Fgfr2tm1Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N)
abnormal thymus morphology J:101174
bronchiolectasis J:101174
decreased osteoclast cell number J:101174
Fgfr2tm3Dsn/Fgfr2tm3Dsn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal thymus development J:67731
Fgfr3tm1.1(FGFR3*)Ytc/Fgfr3+
(involves: 129)
decreased osteoclast cell number J:287271
Fgfr3tm1.1(FGFR3*)Ytc/Fgfr3tm1.1(FGFR3*)Ytc
(involves: 129)
decreased osteoclast cell number J:287271
Fgfr3tm1Led/Fgfr3tm1Led
(involves: 129S6/SvEvTac)
increased osteoclast cell number J:32105
Fgfr3tm2Llm/Fgfr3+
Tg(CMV-cre)1Ipc/?

(involves: 129S2/SvPas * C57BL/6 * SJL)
increased osteoclast cell number J:183772
Fgfr3tm2Llm/Fgfr3+
Tg(Col2a1-cre)1Bhr/?

(involves: 129S2/SvPas * C57BL/6 * SJL)
increased osteoclast cell number J:183772
Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
(involves: 129S6/SvEvTac)
abnormal osteoclast physiology J:69849
Fgfr4M1Btlr/Fgfr4M1Btlr
(C57BL/6J-Fgfr4M1Btlr)
decreased B-1a cell number J:265097
Fggtm1Lord/Fgg+
(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating fibrinogen level J:129828
Fggtm1Lord/Fggtm1Lord
(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating fibrinogen level J:129828
increased leukocyte cell number J:129828
Fggtm2Jld/Fggtm2Jld
(involves: 129P2/OlaHsd * Black Swiss * C57BL/6)
abnormal neutrophil physiology J:90908
increased susceptibility to bacterial infection J:90908
Fgl1tm1b(EUCOMM)Hmgu/Fgl1tm1b(EUCOMM)Hmgu
(involves: BALB/cJ * C57BL/6N)
decreased B cell number J:269578
dermatitis J:269578
increased anti-double stranded DNA antibody level J:269578
increased central memory CD8 positive, alpha-beta T cell number J:269578
Fgl2tm1Pam/Fgl2+
(involves: 129X1/SvJ * C57BL/6)
decreased susceptibility to Coronaviridae infection J:99453
Fgl2tm1Pam/Fgl2tm1Pam
(involves: 129X1/SvJ * C57BL/6)
decreased susceptibility to Coronaviridae infection J:99453
decreased susceptibility to Coronaviridae infection induced morbidity/mortality J:99453
Fgl2tm1Pam/Fgl2tm1Pam
(B6.129X1-Fgl2tm1Pam)
abnormal B cell physiology J:130895
abnormal dendritic cell physiology J:130895
abnormal Peyer's patch follicle morphology J:130895
abnormal regulatory T cell physiology J:130895
abnormal T cell physiology J:130895
decreased dendritic cell apoptosis J:130895
decreased Peyer's patch number J:130895
decreased susceptibility to Coronaviridae infection J:99453
decreased susceptibility to Coronaviridae infection induced morbidity/mortality J:99453
enlarged spleen J:130895
glomerulonephritis J:130895
increased dendritic cell number J:130895
increased IgA level J:130895
increased IgG level J:130895
increased IgM level J:130895
increased regulatory T cell number J:130895
increased T cell proliferation J:130895
Fgl2tm1Pam/Fgl2tm1Pam
(involves: 129X1/SvJ * C57BL/6J)
increased length of allograft survival J:98997
Fgl2tm1Stsm/Fgl2tm1Stsm
(C57BL/6-Fgl2tm1Stsm)
immune system phenotype J:88648
FgrMhdaali18/Fgr+
(C3HeB/FeJ-FgrMhdaali18)
dermatitis J:112868
increased inflammatory response J:112868
FgrMhdaali18/FgrMhdaali18
(C3HeB/FeJ-FgrMhdaali18)
arthritis J:112868
dermatitis J:112868
Fgrtm1Hev/Fgrtm1Hev
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal interferon-gamma secretion J:131738
Fgrtm1Hev/Fgrtm1Hev
(B6.129S7-Fgrtm1Hev)
abnormal inflammatory response J:113463
Fgrtm1Hev/Fgrtm1Hev
Hcktm1Hev/Hcktm1Hev

(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal macrophage morphology J:59037
abnormal macrophage physiology J:59037
impaired macrophage phagocytosis J:16994
increased susceptibility to bacterial infection J:16994
Fgrtm1Hev/Fgrtm1Hev
Hcktm1Hev/Hcktm1Hev
Lyntm1Sor/Lyntm1Sor

(B6.Cg-Hcktm1Hev Fgrtm1Hev Lyntm1Sor)
abnormal inflammatory response J:113463
abnormal neutrophil physiology J:113463
Fhip1bem1(IMPC)Tcp/Fhip1bem1(IMPC)Tcp
(C57BL/6NCrl-Fhip1bem1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Fhip2bem1(IMPC)Ccpcz/Fhip2bem1(IMPC)Ccpcz
(C57BL/6N-Fhip2bem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fhip2bem1Wwan/Fhip2bem1Wwan
(involves: C57BL/6)
abnormal cytokine level J:302658, J:285283
enlarged spleen J:285283
increased leukocyte cell number J:285283
increased susceptibility to induced colitis J:285283
liver inflammation J:302658
Fhittm1Hbn/Fhit+
(involves: 129X1/SvJ * C57BL/6)
decreased granulocyte number J:71303
increased susceptibility to infection J:71303
Fhittm1Hbn/Fhittm1Hbn
(involves: 129X1/SvJ * C57BL/6)
decreased granulocyte number J:71303
increased susceptibility to infection J:71303
Fig4plt1/Fig4plt1
(involves: 129P2/OlaHsd * C3H * C57BL/6 * CAST/Ei * SJL)
spleen hypoplasia J:122737
Fignfi/Fignfi
(mixed)
conjunctivitis J:13035
eye inflammation J:13035
Fis1tm1.1Itl/Fis1tm1.1Itl
Tg(Ckmm-cre)5Khn/0

(involves: C57BL/6NTac * FVB)
increased circulating interferon-beta level J:290485
increased circulating interleukin-6 level J:290485
increased circulating interleukin-12b level J:290485
increased circulating interleukin-13 level J:290485
Fitm2tm1.1Dls/Fitm2tm1.1Dls
Tg(Fabp4-cre)1Rev/?

(involves: 129S6/SvEvTac * C57BL/6J)
increased circulating tumor necrosis factor level J:212437
Fkbp4em1(IMPC)Mbp/Fkbp4em1(IMPC)Mbp
(C57BL/6N-Fkbp4em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
small spleen J:211773
Fkbp5tm1b(KOMP)Wtsi/Fkbp5tm1b(KOMP)Wtsi
(C57BL/6N-Fkbp5tm1b(KOMP)Wtsi/MbpMmucd)
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Fkbp11em1(IMPC)Mbp/Fkbp11em1(IMPC)Mbp
(C57BL/6N-Fkbp11em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
small spleen J:211773
Fkbp11Gt(OST298786)Lex/Fkbp11Gt(OST298786)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased immunoglobulin level J:103485
increased inflammatory response J:103485
Fkrptm1Scbr/Fkrptm1Scbr
Sox1tm1(cre)Take/Sox1+

(involves: C57BL/6NCrlj * CBA/JNCrlj)
myositis J:207119
Fkrptm1Scbr/Fkrptm1Scbr
Sox1tm1(cre)Take/Sox1+
Tg(CAG-LARGE)126Fmu/0

(involves: C57BL/6NCrlj * C57BL/10 * CBA/Ca * CBA/JNCrlj)
myositis J:207119
Flcntm1Baba/Flcntm1.1Lss
Tg(CAG-cre/Esr1*)1Lbe/0

(involves: 129S1/Sv * 129X1/SvJ)
arrested B cell differentiation J:189078
decreased B cell number J:189078
Flgft/Flgft
(involves: C57BL/6)
skin inflammation J:151110
Flgft/Flgft
(B6.Cg-Flgft)
immune system phenotype J:202453, J:151110
increased IgE level J:202453, J:151110
increased IgG1 level J:151110
increased IgG2a level J:151110
increased IgG level J:151110
increased interferon-gamma secretion J:151110
increased interleukin-4 secretion J:151110
increased interleukin-5 secretion J:151110
increased interleukin-10 secretion J:151110
increased interleukin-13 secretion J:151110
increased interleukin-17 secretion J:151110
increased splenocyte proliferation J:151110
Flgft/Flgft
(Not Specified)
dermatitis J:198332
Flgft/Flgft
(STOCK a/a Tmem79ma Flgft/J)
abnormal cytokine level J:204304
dermatitis J:204304
Flgft/Flgft
Tmem79ma/Tmem79ma

(involves: CBA/CaGr)
blepharitis J:202453
increased IgE level J:202453
skin inflammation J:202453
Flgtm1Amag/Flgtm1Amag
(involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac)
abnormal humoral immune response J:198332
dermatitis J:198332
increased IgE level J:198332
increased IgG1 level J:198332
increased inflammatory response J:229771
increased susceptibility to type IV hypersensitivity reaction J:198332
Flgtm1Amag/Flgtm1Amag
Tg(CD207-Dta)312Dhka/0

(involves: 129S6/SvEvTac * BALB/c * C57BL/6NTac * FVB)
decreased inflammatory response J:229771
Fli1tm1.1Dkw/Fli1+
(B6.129S6-Fli1tm1.1Dkw)
decreased B cell number J:137876
Fli1tm1.1Dkw/Fli1tm1.1Dkw
(B6.129S6-Fli1tm1.1Dkw)
abnormal B cell differentiation J:137876
abnormal class switch recombination J:137876
abnormal humoral immune response J:137876
abnormal splenic cell ratio J:137876
decreased B cell number J:137876
decreased B cell proliferation J:137876
decreased follicular B cell number J:137876
decreased IgG1 level J:137876
decreased IgG3 level J:137876
increased marginal zone B cell number J:137876
increased transitional stage B cell number J:137876
spleen hyperplasia J:137876
Fli1tm1Ber/Fli1tm1Ber
(either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1))
decreased thymocyte number J:33052
Fli1tm1Ber/Fli1tm1Ber
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1)
enlarged spleen J:33052
Fli1tm1Morl/Fli1tm1Morl
Tg(Mx1-cre)1Cgn/0

(involves: 129/Sv * C57BL/6 * CBA)
abnormal leukocyte morphology J:167426
abnormal thrombopoiesis J:167426
decreased granulocyte number J:167426
increased monocyte cell number J:167426
increased NK cell number J:167426
Flicrem1Doi/Flicrem1Doi
(NOD/ShiLtDoi-Flicrem1Doi)
decreased susceptibility to autoimmune diabetes J:241346
insulitis J:241346
Flnatm1.2Caw/Flna+
(involves: 129S4/SvJae * C57BL/6)
increased leukocyte cell number J:118252
Flnbtm1b(KOMP)Wtsi/Flnb+
(C57BL/6N-Flnbtm1b(KOMP)Wtsi/H)
decreased neutrophil cell number J:211773
Flot1tm1.1Arte/Flot1tm1.1Arte
(involves: C57BL/6J)
abnormal leukocyte physiology J:166672
impaired neutrophil chemotaxis J:166672
impaired neutrophil recruitment J:166672
Flt1tm1.1Fong/Flt1tm1.1Fong
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+

(involves: 129S6/SvEvTac * C57BL/6NCr * CD-1)
increased macrophage cell number J:202202
Flt1tm1Msh/Flt1tm1Msh
(involves: 129S4/SvJae * C57BL/6J)
impaired macrophage chemotaxis J:49507
Flt3em1(IMPC)Ccpcz/Flt3em1(IMPC)Ccpcz
(C57BL/6NCrl-Flt3em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
decreased effector memory T-helper cell number J:211773
decreased NK cell number J:211773
Flt3m1Btlr/Flt3m1Btlr
(C57BL/6J-Flt3m1Btlr)
abnormal dendritic cell antigen presentation J:159599
abnormal dendritic cell physiology J:159599
abnormal macrophage physiology J:105543
abnormal NK cell physiology J:159599
decreased circulating interferon-alpha level J:159599
decreased circulating interferon-gamma level J:159599
decreased circulating interleukin-12 level J:159599
decreased dendritic cell number J:159599
decreased interferon-alpha secretion J:159599
decreased interferon-gamma secretion J:159599
decreased interleukin-12 secretion J:159599
decreased NK cell number J:159599
decreased plasmacytoid dendritic cell number J:159599
decreased splenocyte number J:159599
increased circulating interleukin-6 level J:159599
increased circulating tumor necrosis factor level J:159599
increased susceptibility to Herpesvirales infection J:105543
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:159599
increased susceptibility to Riboviria infection J:105543
small lymph nodes J:159599
Flt3tm1.1Dosm/Flt3+
(B6.129(C)-Flt3tm1.1Dosm)
abnormal spleen morphology J:205200
arrested B cell differentiation J:205200
enlarged spleen J:205200
increased spleen white pulp amount J:205200
Flt3tm1Dgg/Flt3+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal B cell differentiation J:126003
decreased B cell number J:126003
decreased mature B cell number J:126003
decreased T cell number J:126003
enlarged spleen J:126003
increased granulocyte number J:126003
increased leukocyte cell number J:126003
increased monocyte cell number J:126003
increased spleen red pulp amount J:126003
increased spleen white pulp amount J:126003
Flt3tm1Dgg/Flt3+
Kmt2atm1Clgr/Kmt2a+

(involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J)
enlarged spleen J:189096
increased leukocyte cell number J:189096
Flt3tm1Dgg/Flt3tm1Dgg
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal B cell differentiation J:126003
decreased B cell number J:126003
decreased mature B cell number J:126003
decreased T cell number J:126003
enlarged spleen J:126003
increased granulocyte number J:126003
increased leukocyte cell number J:126003
increased monocyte cell number J:126003
increased spleen red pulp amount J:126003
increased spleen white pulp amount J:126003
Flt3tm1Dgg/Flt3tm1Dgg
Kmt2atm1Clgr/Kmt2a+

(involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J)
enlarged spleen J:189096
increased leukocyte cell number J:189096
Flt3tm1Dosm/Flt3+
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Flt3tm1Dosm Tg(Mx1-cre)1Cgn)
abnormal spleen white pulp morphology J:133528
arrested B cell differentiation J:133528
decreased B cell number J:133528
decreased leukocyte cell number J:133528
decreased lymphocyte cell number J:133528
decreased neutrophil cell number J:133528
decreased pre-B cell number J:133528
enlarged spleen J:133528
increased dendritic cell number J:133528
increased granulocyte number J:133528
increased leukocyte cell number J:133528
increased monocyte cell number J:133528
increased neutrophil cell number J:133528
increased pro-B cell number J:133528
intermingled spleen red and white pulp J:133528
Flt3tm1Irl/Flt3tm1Irl
(either: 129S/SvEv-Flt3tm1Irl or (involves: 129S/SvEv * C57BL/6J))
abnormal B cell differentiation J:27238, J:99149
decreased pre-B cell number J:27238
decreased pro-B cell number J:27238
Flt3tm1Irl/Flt3tm1Irl
KitW/KitW-v

(involves: 129S/SvEv * C57BL/6)
abnormal leukocyte morphology J:27238
abnormal myelopoiesis J:27238
abnormal T cell number J:27238
decreased B cell number J:27238
decreased double-negative T cell number J:27238
decreased double-positive T cell number J:27238
decreased lymphocyte cell number J:27238
decreased pre-B cell number J:27238
decreased pro-B cell number J:27238
thymus hypoplasia J:27238
Flt3tm2.1Dosm/Flt3+
(B6.129(C)-Flt3tm2.1Dosm)
abnormal B cell morphology J:205200
abnormal myelopoiesis J:205200
abnormal spleen morphology J:205200
enlarged spleen J:205200
increased leukocyte cell number J:205200
increased pre-pro B cell number J:205200
increased pro-B cell number J:205200
increased spleen white pulp amount J:205200
intermingled spleen red and white pulp J:205200
myeloid hyperplasia J:205200
Flt3ltm1Imx/Flt3ltm1Imx
(C57BL/6-Flt3ltm1Imx)
abnormal dendritic cell morphology J:62536, J:89868
abnormal immature B cell morphology J:62536
abnormal immune system cell morphology J:62536
abnormal immune system organ morphology J:62536
abnormal leukocyte morphology J:62536
decreased B cell number J:79569
decreased double-negative T cell number J:79569
decreased leukocyte cell number J:62536
decreased lymphocyte cell number J:62536
decreased myeloid dendritic cell number J:62536, J:89868
decreased NK cell number J:62536
decreased plasmacytoid dendritic cell number J:62536, J:89868
decreased pre-B cell number J:79569
decreased pro-B cell number J:79569, J:62536
impaired myelopoiesis J:62536
increased IgM level J:62536
increased length of allograft survival J:89868
increased neutrophil cell number J:62536
lymph node hypoplasia J:62536
spleen hypoplasia J:62536
Flt3ltm1Imx/Flt3ltm1Imx
(involves: C57BL/6)
abnormal dendritic cell antigen presentation J:223508
abnormal dendritic cell chemotaxis J:223508
abnormal memory T cell physiology J:189122
abnormal T-helper 1 physiology J:189122
decreased CD11b-high dendritic cell number J:223508
decreased CD103-positive CD11b-low dendritic cell number J:223508
decreased dendritic cell number J:189122
decreased macrophage cell number J:189122
decreased monocyte cell number J:189122
decreased NK cell number J:189122
decreased plasmacytoid dendritic cell number J:189122
increased neutrophil cell number J:189122
increased susceptibility to parasitic infection J:189122
Flt4Chy/Flt4+
(involves: C3H)
abnormal lymph circulation J:72387
abnormal lymphangiogenesis J:177405
abnormal lymphatic vessel morphology J:72387
Flt4Chy/Flt4Chy
(involves: C3H)
abnormal lymphangiogenesis J:177405
absent lymphatic vessels J:177405
Flt4tm1.1Ichi/Flt4+
Krastm1Mok/Kras+

(involves: 129S/SvEv * C57BL/6)
lymphatic vessel hypoplasia J:159024
Flt4tm1.1Ichi/Flt4+
Krastm1Mok/Kras+
Tg(HRAS)2Jic/0

(involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2)
lymphatic vessel hypoplasia J:159024
Flt4tm1.2Yhe/Flt4tm1.2Yhe
(involves: 129/Sv * C57BL/6J * FVB/N)
abnormal lymphangiogenesis J:177405
absent lymphatic vessels J:177405
Flt4tm1Ali/Flt4+
Nrp2tm1Ddg/Nrp2+

(involves: C57BL/6)
abnormal lymphangiogenesis J:156869
Flt4tm1Ali/Flt4+
Nrp2tm1Ddg/Nrp2tm1Ddg

(involves: C57BL/6)
abnormal lymphangiogenesis J:156869
Flt4tm1Ali/Flt4+
Tmem204tm1.1Ali/Tmem204tm1.1Ali

(involves: BALB/c * C57BL/6)
abnormal lymphatic vessel smooth muscle morphology J:159519
enlarged lymphatic vessel J:159519
Flt4tm1Ali/Flt4tm2Ali
(involves: 129S1/Sv * 129X1/SvJ * ICR)
absent lymphatic vessels J:137909
Flt4tm2Ali/Flt4+
(involves: 129S1/Sv * 129X1/SvJ * ICR)
abnormal lymph circulation J:137909
abnormal lymphatic vessel morphology J:137909
Flt4tm2Ali/Flt4tm2Ali
(involves: 129S1/Sv * 129X1/SvJ * ICR)
absent lymphatic vessels J:137909
Flvcr1tm1.1Jlab/Flvcr1tm1.1Jlab
(involves: 129S4/SvJae * C57BL/6 * DBA/2)
abnormal spleen morphology J:132057
enlarged spleen J:132057
Flvcr2tm1.2Tda/Flvcr2tm1.2Tda
(involves: C57BL/6J)
brain inflammation J:287134
Flvcr2tm1a(EUCOMM)Hmgu/Flvcr2tm1a(EUCOMM)Hmgu
(C57BL/6N-Flvcr2tm1a(EUCOMM)Hmgu/Wtsi)
blood in lymph vessels J:239583
fm/fm
(involves: CBA/H)
abnormal lymph node morphology J:275
abnormal Peyer's patch morphology J:275
abnormal spleen morphology J:5417, J:275
abnormal thymus morphology J:275
Fmnl1tm1.2Sdb/Fmnl1tm1.2Sdb
Lyz2tm1(cre)Ifo/Lyz2tm1(cre)Ifo

(involves: C3H * C57BL/6 * FVB/N)
abnormal Kupffer cell morphology J:250144
abnormal macrophage morphology J:250144
abnormal macrophage physiology J:250144
decreased macrophage cell number J:250144
impaired macrophage chemotaxis J:250144
Fmo3em1(IMPC)Mbp/Fmo3em1(IMPC)Mbp
(C57BL/6N-Fmo3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Fmo5em1(IMPC)Mbp/Fmo5em1(IMPC)Mbp
(C57BL/6N-Fmo5em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Fmodtm1Aol/Fmodtm1Aol
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
osteoarthritis J:79115
Fmodtm1Aol/Fmodtm1Aol
Lumtm1Chak/Lumtm1Chak

(involves: 129S1/Sv * 129X1/SvJ * CD-1)
osteoarthritis J:79115
Fn1tm1Bwg/Fn1tm1Bwg
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:90917
Fndc3aem1(IMPC)Tcp/Fndc3aem1(IMPC)Tcp
(C57BL/6N-Fndc3aem1(IMPC)Tcp/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Fndc4tm1.1Mabo/Fndc4tm1.1Mabo
(involves: C57BL/6 * BALB/c)
increased susceptibility to induced colitis J:236896
Fndc9tm1.1(KOMP)Vlcg/Fndc9tm1.1(KOMP)Vlcg
(C57BL/6N-Fndc9tm1.1(KOMP)Vlcg/Ucd)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Fnip1Gt(RRM154)Byg/Fnip1Gt(RRM154)Byg
(involves: 129P2/OlaHsd * C57BL/6J)
absent B cells J:189078
absent B-2 B cells J:189078
arrested B cell differentiation J:189078
decreased B cell number J:189078
decreased B-1 B cell number J:189078
decreased mature B cell number J:189078
decreased pre-B cell number J:189078
decreased transitional stage B cell number J:189078
increased B cell apoptosis J:189078
increased pro-B cell number J:189078
small spleen J:189078
Fnip1Gt(RRM154)Byg/Fnip1Gt(RRM154)Byg
Ightm2Cgn/Ightm2Cgn

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL)
absent B cells J:189078
absent B-2 B cells J:189078
decreased B-1 B cell number J:189078
Fnip1Gt(RRM154)Byg/Fnip1Gt(RRM154)Byg
Tg(BCL2)22Wehi/0

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL)
increased B cell number J:189078
Fnip1Gt(RRM154)Byg/Fnip1Gt(RRM154)Byg
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL)
absent B cells J:189078
absent B-2 B cells J:189078
decreased B-1 B cell number J:189078
increased immature B cell number J:189078
Fnip1LPAB.1/Fnip1LPAB.1
(C57BL/6J-Fnip1LPAB.1)
abnormal B cell physiology J:187318
absent B cells J:187318
arrested B cell differentiation J:187318
decreased B-1 B cell number J:187318
decreased IgE level J:187318
decreased IgG1 level J:187318
decreased IgG2a level J:187318
decreased IgG level J:187318
decreased IgM level J:187318
increased B cell apoptosis J:187318
Fnip1LPAB.1/Fnip1LPAB.1
Tg(IghMyc)22Bri/0

(involves: C57BL * C57BL/6J * SJL)
increased B cell apoptosis J:187318
Fnip1m1Btlr/Fnip1m1Btlr
(C57BL/6J-Fnip1m1Btlr)
abnormal splenocyte morphology J:234285
absent B cells J:234285
decreased IgM level J:234285
decreased marginal zone B cell number J:234285
Fnip1m2Btlr/Fnip1m2Btlr
(C57BL/6J-Fnip1m2Btlr)
decreased B cell number J:265134
increased B-1 B cell number J:265134
increased CD4-positive, alpha-beta T cell number J:265134
increased single-positive T cell number J:265134
increased T cell number J:265134
Fnip1M3Btlr/Fnip1M3Btlr
(C57BL/6J-Fnip1M3Btlr)
abnormal B cell differentiation J:272802
Fnip1tm1.2Baba/Fnip1tm1.2Baba
(involves: C57BL/6 * C57BL/6J * FVB/N * SJL)
absent B cells J:189078
absent B-2 B cells J:189078
arrested B cell differentiation J:189078
decreased B cell number J:189078
decreased B-1 B cell number J:189078
decreased mature B cell number J:189078
decreased pre-B cell number J:189078
decreased transitional stage B cell number J:189078
increased B cell apoptosis J:189078
increased pro-B cell number J:189078
small spleen J:189078
Fnip1tm1.2Baba/Fnip1tm1.2Baba
Ightm2Cgn/Ightm2Cgn

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL)
absent B cells J:189078
absent B-2 B cells J:189078
decreased B-1 B cell number J:189078
Fnip1tm1.2Baba/Fnip1tm1.2Baba
Tg(BCL2)22Wehi/0

(involves: C57BL/6 * FVB/N * SJL)
increased B cell number J:189078
Fnip1tm1.2Baba/Fnip1tm1.2Baba
Tg(IghelMD4)4Ccg/0

(involves: C57BL/6 * C57BL/6J * FVB/N * SJL)
absent B cells J:189078
absent B-2 B cells J:189078
decreased B-1 B cell number J:189078
increased immature B cell number J:189078
Fntbtm1Bbd/Fntbtm1.1Bbd
Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL)
small spleen J:98944
Fntbtm1Bbd/Fntbtm1Bbd
Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL)
small spleen J:98944
Fostm1Pa/Fostm1Pa
(involves: 129X1/SvJ * C57BL/6J)
abnormal lymphopoiesis J:3233
Fostm1Wag/Fostm1Wag
(involves: 129S2/SvPas)
decreased osteoclast cell number J:65766
Fostm1Wag/Fostm1Wag
(involves: 129S2/SvPas * C57BL/6)
abnormal cytokine secretion J:118693
abnormal macrophage physiology J:118693
abnormal spleen morphology J:3493
abnormal spleen white pulp morphology J:3493
abnormal thymus size J:3493
decreased B cell number J:3493
decreased double-positive T cell number J:3493
decreased splenocyte number J:3493
decreased thymocyte number J:3493
increased macrophage apoptosis J:118693
increased macrophage cytokine production J:118693
increased susceptibility to bacterial infection J:118693
increased T cell number J:3493
Fostm1Wag/Fostm2(Fosl1)Wag
(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
decreased osteoclast cell number J:65766
Fostm3.1Wag/Fostm3.1Wag
(involves: 129P2/OlaHsd * C57BL/6 * SJL)
decreased interleukin-10 secretion J:175064
increased susceptibility to endotoxin shock J:175064
increased tumor necrosis factor secretion J:175064
Fostm4.1Wag/Fostm4.1Wag
(involves: 129P2/OlaHsd * C57BL/6 * SJL)
decreased interleukin-10 secretion J:175064
increased interleukin-6 secretion J:175064
increased susceptibility to endotoxin shock J:175064
increased tumor necrosis factor secretion J:175064
Fostm5.1Wag/Fostm5.1Wag
(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal osteoclast differentiation J:175064
decreased interleukin-10 secretion J:175064
decreased osteoclast cell number J:175064
increased circulating tumor necrosis factor level J:175064
increased interleukin-6 secretion J:175064
increased susceptibility to endotoxin shock J:175064
increased tumor necrosis factor secretion J:175064
Fostm6.1Wag/Fostm6.1Wag
(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal osteoclast differentiation J:175064
increased circulating interleukin-6 level J:175064
increased circulating interleukin-10 level J:175064
increased circulating tumor necrosis factor level J:175064
increased susceptibility to endotoxin shock J:175064
Fostm7Wag/Fostm7Wag
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
decreased interleukin-10 secretion J:175064
increased circulating interleukin-6 level J:175064
increased circulating interleukin-10 level J:175064
increased circulating tumor necrosis factor level J:175064
increased interleukin-6 secretion J:175064
increased susceptibility to endotoxin shock J:175064
increased tumor necrosis factor secretion J:175064
Fostm7Wag/Fostm7Wag
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:190150
Fosl2tm2.1Wag/Fosl2tm2.1Wag
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:137646
abnormal osteoclast morphology J:137646
abnormal osteoclast physiology J:137646
increased osteoclast cell number J:137646
Fosl2tm2Wag/Fosl2tm2Wag
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:137646
Fosl2tm2Wag/Fosl2tm2Wag
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

(involves: 129P2/OlaHsd * C57BL/6 * CD-1)
abnormal osteoclast morphology J:211215
Foxa1tm1(cre)Sew/Foxa1+
Mst1rtm1Sew/Mst1rtm1Sew

(involves: 129P2/OlaHsd * CD-1 * NIH Black Swiss)
decreased susceptibility to bacterial infection J:105979
Foxa2tm1.1Khk/Foxa2+
(involves: 129P2/OlaHsd * C57BL/6 * CD-1)
respiratory system inflammation J:284174
Foxa2tm1Khk/Foxa2tm1Khk
Tg(Scgb1a1-rtTA)1Jaw/0
Tg(tetO-cre)1Jaw/0

(Not Specified)
immune system phenotype J:88601
Foxa2tm1Khk/Foxa2tm1Khk
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0

(involves: 129 * 129P2/OlaHsd * C57BL/6)
increased macrophage cell number J:88601
increased neutrophil cell number J:88601
Foxc2tm1.1Miu/Foxc2tm1.1Miu
Tg(Tek-cre)1Ywa/0

(involves: C57BL/6 * C57BL/6J * SJL)
abnormal lymphatic vessel morphology J:316530
Foxc2tm1Miu/Foxc2+
(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J)
abnormal lymph circulation J:83436
abnormal thoracic duct morphology J:83436
enlarged lymph nodes J:83436
increased lymph node number J:83436
lymphangiectasis J:83436
lymphatic vessel hyperplasia J:83436
Foxf1em1Vvk/Foxf1+
(involves: C57BL/6 * DBA/2)
lung inflammation J:296328
Foxh1b2b2662Clo/Foxh1b2b2662Clo
(C57BL/6J-Foxh1b2b2662Clo)
absent spleen J:175213
thymus hypoplasia J:175213
Foxh1tm1Hmd/Foxh1tm1.1Hmd
Tg(Leftb-cre)1Hmd/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6Cr)
spleen hypoplasia J:82311
Foxi3em3Akg/Foxi3tm1.2Akg
(involves: 129X1/SvJ * C57BL/6)
athymia J:336768
Foxj3tm1b(EUCOMM)Wtsi/Foxj3+
(C57BL/6N-Foxj3tm1b(EUCOMM)Wtsi/Bay)
increased leukocyte cell number J:211773
Foxm1tm1Rhc/Foxm1tm1Rhc
Tg(Tek-cre)1Ywa/0

(involves: 129X1/SvJ * C57BL/6 * SJL)
lung inflammation J:167773
Foxn1nu-2J/Foxn1nu-2J
(B6(SJL)-Foxn1nu-2J/GrsrJ)
athymia J:192383
Foxn1nu-StL/Foxn1nu-StL
(involves: C57BL/6)
absent T cells J:63313
athymia J:63313
Foxn1nu-StL/Foxn1tm1Tbo
(involves: 129S1/Sv * C57BL/6)
abnormal thymus development J:63313
athymia J:63313
Foxn1nu-str/Foxn1nu-str
(AKR/J-Foxn1nu-str/J)
abnormal humoral immune response J:30715
abnormal immune system cell morphology J:30715
abnormal immune system morphology J:24755
abnormal immune system organ morphology J:30715
abnormal immune system physiology J:30715
abnormal Peyer's patch germinal center morphology J:30715
abnormal Peyer's patch morphology J:30715
athymia J:24755
decreased immunoglobulin level J:30715
decreased lymphocyte cell number J:30715
decreased T cell number J:30715
increased eosinophil cell number J:30715
increased granulocyte number J:30715
increased length of allograft survival J:30715
increased neutrophil cell number J:30715
lymph node hypoplasia J:30715
spleen hypoplasia J:30715
Foxn1nu-Y/Foxn1nu-Y
(101/HY-Foxn1nu-Y)
abnormal thymus development J:4060
absent T cells J:4060
athymia J:4060, J:29022
Foxn1nu/Foxn1+
(C.Cg-Foxn1nu)
small thymus J:7330
Foxn1nu/Foxn1+
(involves: BALB/c)
blepharitis J:12543
increased incidence of corneal inflammation J:12543
increased susceptibility to Herpesvirales infection J:12543
Foxn1nu/Foxn1+
(NFS.Cg-Foxn1nu)
abnormal thymus morphology J:7330
small thymus J:7330
Foxn1nu/Foxn1+
(B6N.Cg-Foxn1nu)
small thymus J:7330
Foxn1nu/Foxn1+
(C3N.Cg-Foxn1nu)
small thymus J:7330
Foxn1nu/Foxn1nu
(involves: NMRI)
abnormal thymus development J:6363
Foxn1nu/Foxn1nu
(Not Specified)
abnormal lymph node T cell domain morphology J:202296
abnormal Peyer's patch germinal center morphology J:202296
abnormal spleen morphology J:202296
abnormal splenic cell ratio J:202296
abnormal thymus morphology J:202297
athymia J:202296, J:5059
decreased leukocyte cell number J:5059
small spleen J:202296
Foxn1nu/Foxn1nu
(B6NTac.Cg-Foxn1nu/Tac)
decreased susceptibility to parasitic infection J:64283
Foxn1nu/Foxn1nu
(involves: BALB/c)
abnormal circulating cytokine level J:50903
blepharitis J:12543
decreased circulating interleukin-2 level J:50903
decreased circulating interleukin-6 level J:50903
decreased circulating tumor necrosis factor level J:50903
decreased interferon-gamma secretion J:50903
decreased susceptibility to bacterial infection J:50903
increased susceptibility to Herpesvirales infection J:12543
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:12543
Foxn1nu/Foxn1nu
(involves: C57BL/10Sn * C57BR/cd)
abnormal thymus development J:7898
Foxn1nu/Foxn1nu
(involves: CD-1)
athymia J:106251
Foxn1nu/Foxn1nu
(involves: CBA)
abnormal lymph node morphology J:202808
abnormal spleen physiology J:202299
abnormal T cell activation J:202299
decreased leukocyte cell number J:202299
decreased lymphocyte cell number J:202299
decreased T cell number J:202808
increased length of allograft survival J:202299
Foxn1nu/Foxn1nu
Fv4r/Fv4r

(involves: BALB/c)
decreased susceptibility to Retroviridae infection J:5714, J:5684
Foxn1nu/Foxn1nu
Map3k14aly/Map3k14aly

(involves: BALB/cAJcl * C57BL/6J)
absent B cells J:96579
absent lymph nodes J:96579
absent Peyer's patches J:96579
athymia J:96579
decreased gamma-delta intraepithelial T cell number J:96579
decreased T cell number J:96579
Foxn1nu/Foxn1nu
Tg(Foxn1)E1Hon/0

(involves: CD-1)
athymia J:33866
Foxn1nu/Foxn1nu
Tgfb1tm1Doe/Tgfb1tm1Doe

(involves: 129S2/SvPas * BALB/c * CF-1)
abnormal T cell physiology J:99033
decreased inflammatory response J:99033
Foxn1nu/Foxn1tm1.1Dmsu
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129/Sv * C57BL/6 * CBA * SJL)
abnormal thymus epithelium morphology J:159773
decreased thymocyte number J:159773
increased thymocyte apoptosis J:159773
Foxn1sepe/Foxn1sepe
(BALB/c-Foxn1sepe)
athymia J:227974
Foxn1tm1.1(KOMP)Vlcg/Foxn1tm1.1(KOMP)Vlcg
(C57BL/6N-Foxn1tm1.1(KOMP)Vlcg/Tcp)
abnormal thymus morphology J:211773
athymia J:211773
Foxn1tm1.1Cbln/Foxn1+
(involves: 129P2/OlaHsd * C57BL/6)
thymus hyperplasia J:177992
Foxn1tm1.1Cbln/Foxn1+
Tg(Zp3-cre)3Mrt/?

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * FVB/N)
immune system phenotype J:177992
Foxn1tm1.1Cbln/Foxn1tm1.1Cbln
(involves: 129P2/OlaHsd * C57BL/6)
abnormal lymphocyte cell number J:177992
decreased single-positive T cell number J:177992
increased DN1 thymic pro-T cell number J:177992
increased double-positive T cell number J:177992
thymus hypoplasia J:177992
Foxn1tm1.1Cbln/Foxn1tm1Tbo
(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
absent T cells J:177992
small thymus J:177992
Foxn1tm1.1Cbln/Foxn1tm1Tbo
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
immune system phenotype J:177992
Foxn1tm1.1Dmsu/Foxn1tm1.1Dmsu
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129/Sv * C57BL/6 * CBA * SJL)
abnormal thymus morphology J:159773
decreased double-positive T cell number J:159773
decreased thymocyte number J:159773
small thymus J:159773
thymus atrophy J:159773
Foxn1tm1.1Dmsu/Foxn1tm1.1Dmsu
Tg(KRT5-cre/ERT2)2Ipc/0

(involves: 129/Sv * C57BL/6 * SJL)
abnormal thymus corticomedullary boundary morphology J:159773
abnormal thymus medulla morphology J:159773
decreased thymocyte number J:159773
small thymus J:159773
thymus atrophy J:159773
Foxn1tm1.1Dmsu/Foxn1tm1.1Dmsu
Tg(KRT18-cre/ERT2)1Rgo/0

(involves: 129/Sv * C57BL/6 * FVB/N * SJL)
immune system phenotype J:159773
Foxn1tm1Dmsu/Foxn1tm1Dmsu
(involves: 129/Sv * C57BL/6)
athymia J:159773
Foxn1tm1Nrm/Foxn1tm1Nrm
(involves: 129X1/SvJ * C57BL/6J)
abnormal CD4-positive, alpha beta T cell morphology J:86255
abnormal CD8-positive, alpha beta T cell morphology J:86255
abnormal T cell differentiation J:86255
abnormal thymus development J:86255
abnormal thymus epithelium morphology J:86255
absent thymus cortex J:86255
absent thymus medulla J:86255
decreased CD4-positive, alpha-beta T cell number J:86255
decreased double-negative T cell number J:86255
decreased double-positive T cell number J:86255
decreased T cell number J:86255
decreased thymocyte number J:86255
small thymus J:86255
thymus cyst J:86255
Foxn1tm1Tbo/Foxn1tm1Tbo
(involves: 129S1/Sv)
abnormal leukocyte cell number J:33796
abnormal thymus development J:33796
abnormal thymus epithelium morphology J:177992
abnormal thymus morphology J:33796
absent T cells J:33796
athymia J:33796
increased B cell number J:33796
Foxn1tm2Nrm/Foxn1tm2Nrm
(either: (involves: 129/Sv) or (involves: C57BL/6))
immune system phenotype J:125817
Foxn1tm2Tbo/Foxn1tm2Tbo
Tg(KRT14-cre/ERT2)1Ipc/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
increased T cell number J:110046
Foxn1tm3(cre)Nrm/Foxn1+
Gt(ROSA)26Sortm1(Tbx1)Rche/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NHsd)
abnormal thymus development J:214094
abnormal thymus epithelium morphology J:214094
decreased thymocyte number J:214094
thymus hypoplasia J:214094
Foxn1tm3(cre)Nrm/Foxn1+
Mir205hgtm1Oers/Mir205hgtm1Oers

(B6(Cg)-Mir205hgtm1Oers Foxn1tm3(cre)Nrm)
decreased thymocyte number J:278363
decreased thymus weight J:278363
thymus hypoplasia J:278363
Foxn1tm3(cre)Nrm/Foxn1tm3(cre)Nrm
(either: (involves: 129/Sv) or (involves: C57BL/6))
immune system phenotype J:125817
Foxo1tm1.1Rdp/Foxo1+
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * 129S1/Sv)
increased B cell number J:157297
Foxo1tm1.1Stlp/Foxo1tm1.1Stlp
Tg(Lck-cre)1Cwi/0

(involves: 129S4/SvJae)
abnormal single-positive T cell number J:154205
decreased CD8-positive, alpha-beta T cell number J:154205
decreased double-positive T cell number J:154205
decreased T cell number J:154205
decreased T cell proliferation J:154205
decreased thymocyte apoptosis J:154205
increased CD4-positive, alpha-beta T cell number J:154205
increased CD8-positive, alpha-beta T cell number J:154205
small lymphoid organs J:154205
small spleen J:154205
Foxo1tm1Flv/Foxo1tm1Flv
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ)
abnormal inflammatory response J:189962
abnormal regulatory T cell physiology J:189962
enlarged lymph nodes J:189962
enlarged spleen J:189962
increased CD4-positive, alpha-beta T cell number J:189962
increased CD8-positive, alpha-beta T cell number J:189962
increased interferon-gamma secretion J:189962
increased regulatory T cell number J:189962
increased T cell number J:189962
increased T cell proliferation J:189962
Foxo1tm1Flv/Foxo1tm1Flv
Gt(ROSA)26Sortm1(CAG-FOXO1,GFP)Moli/Gt(ROSA)26Sor+
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6)
immune system phenotype J:189962
Foxo1tm1Flv/Foxo1tm1Flv
Ifngtm1Ts/Ifngtm1Ts
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129S6/SvEvTac * 129S7/SvEvBrd * 129X1/SvJ)
immune system phenotype J:189962
increased CD4-positive, alpha-beta T cell number J:189962
increased CD8-positive, alpha-beta T cell number J:189962
Foxo1tm1Flv/Foxo1tm1Flv
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6)
increased interferon-gamma secretion J:189962
Foxo1tm1Flv/Foxo1tm1Flv
Rag1tm1Mom/Rag1tm1Mom
Tg(CD2-Il7r)1Asin/?
Tg(Cd4-cre)1Cwi/?
Tg(TcraTcrb)425Cbn/?

(involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2)
decreased T cell number J:147057
Foxo1tm1Flv/Foxo1tm1Flv
Rag1tm1Mom/Rag1tm1Mom
Tg(Cd4-cre)1Cwi/?
Tg(TcraTcrb)425Cbn/?

(involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2)
decreased T cell number J:147057
Foxo1tm1Flv/Foxo1tm1Flv
Tg(Cd4-cre)1Cwi/?

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:147057
abnormal CD8-positive, alpha-beta T cell physiology J:147057
abnormal T cell activation J:147057
abnormal T cell physiology J:147057
enlarged lymph nodes J:147057
increased anti-double stranded DNA antibody level J:147057
increased anti-nuclear antigen antibody level J:147057
increased single-positive T cell number J:147057
increased susceptibility to induced colitis J:147057
increased T cell proliferation J:147057
Foxo1tm1Rdp/Foxo1tm1.1Rdp
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * 129S1/Sv)
absent marginal zone B cells J:157297
increased B cell number J:157297
Foxo1tm2.1Dac/Foxo1tm2.1Dac
(B6.Cg-Foxo1tm2.1Dac)
decreased circulating tumor necrosis factor level J:179687
Foxo3Gt(XAO26)Byg/Foxo3Gt(XAO26)Byg
(involves: 129P2/OlaHsd)
abnormal immune system organ morphology J:93593
abnormal T cell activation J:93593
abnormal T cell physiology J:93593
enlarged lymph nodes J:93593
enlarged spleen J:93593
increased inflammatory response J:93593
increased T cell proliferation J:93593
kidney inflammation J:93593
lung inflammation J:93593
lymphoid hyperplasia J:93593
salivary gland inflammation J:93593
spleen hyperplasia J:93593
Foxo3tm1.1Rdp/Foxo3tm1.1Rdp
(involves: 129S6/SvEvTac * FVB/N)
dermatitis J:118179
Foxo3tm1Nmt/Foxo3tm1Nmt
(B6.Cg-Foxo3tm1Nmt)
abnormal NK cell morphology J:123409
increased NK cell number J:123409
Foxo6tm1(KOMP)Vlcg/Foxo6tm1(KOMP)Vlcg
(B6J.B6NTac-Foxo6tm1(KOMP)Vlcg)
abnormal Kupffer cell morphology J:236585
impaired macrophage chemotaxis J:236585
Foxp1tm1.1Pwt/Foxp1tm1.1Pwt
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
abnormal T cell activation J:156832
decreased CD4-positive, alpha-beta T cell number J:156832
decreased CD8-positive, alpha-beta T cell number J:156832
immune system phenotype J:156832
increased T cell apoptosis J:156832
Foxp1tm1Rao/Foxp1tm1Rao
(B6.129-Foxp1tm1Rao)
abnormal B cell differentiation J:112644
abnormal B cell physiology J:112644
arrested B cell differentiation J:112644
decreased mature B cell number J:112644
Foxp2tm2.2Woen/Foxp2+
(involves: C57BL/6 * C57BL/6J)
increased CD4-positive, alpha-beta T cell number J:150425
increased CD8-positive, alpha-beta T cell number J:150425
Foxp3sf/Y
(either: 129Rl.Cg-Foxp3sf or (involves: 101/Rl * C3Hf/Rl * STOCK MR))
abnormal B cell physiology J:11262
abnormal lymph node B cell domain morphology J:11262
abnormal lymph node medullary cord morphology J:11262
abnormal lymph node morphology J:11262
abnormal lymph node T cell domain morphology J:11262
abnormal lymphocyte morphology J:11262
abnormal macrophage morphology J:11262
abnormal spleen morphology J:11262
abnormal spleen white pulp morphology J:11262
abnormal thymus cortex morphology J:11262
abnormal thymus morphology J:11262
absent spleen marginal zone J:11262
blepharitis J:11262
decreased spleen B cell follicle number J:11262
dermatitis J:11262
enlarged lymph nodes J:11262
increased IgG level J:11262
increased IgM level J:11262
increased inflammatory response J:11262
increased leukocyte cell number J:11262
increased spleen red pulp amount J:11262
increased spleen weight J:11262
liver inflammation J:11262
small thymus J:11262
Foxp3sf/Y
(involves: 101/H * C3H/HeH * STOCK MR)
abnormal spleen morphology J:10398
conjunctivitis J:10398
increased leukocyte cell number J:10398
increased spleen red pulp amount J:10398
increased spleen weight J:10398
increased spleen white pulp amount J:10398
intermingled spleen red and white pulp J:10398
Foxp3sf/?
(Not Specified)
liver inflammation J:138808
lung inflammation J:138808
Foxp3sf/Y
(B6.Cg-Foxp3sf)
abnormal CD4-positive, alpha beta T cell morphology J:82560
abnormal CD4-positive, alpha-beta T cell physiology J:82560
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:82560
Foxp3sf/Y
(B6.Cg-Foxp3sf/J)
lung inflammation J:125129
salivary gland inflammation J:125129
skin inflammation J:125129
Foxp3sfOtcspf/Y
(involves: 129/Rl)
enlarged lymph nodes J:20865
enlarged spleen J:20865
increased CD4-positive, alpha-beta T cell number J:20865
Foxp3sf/Foxp3sf
Tg(Rorc-EGFP)1Ebe/?

(involves: C57BL/6)
abnormal effector T cell morphology J:137020
Foxp3tm1(CD2/CD52)Shori/Foxp3tm1(CD2/CD52)Shori
(involves: C57BL/6)
decreased regulatory T cell number J:171378
increased susceptibility to type IV hypersensitivity reaction J:171378
Foxp3tm1(cre)Saka/Y
(involves: BALB/c)
increased autoantibody level J:140085
stomach inflammation J:140085
Foxp3tm1.1Ayr/Y
(involves: 129S1/Sv * 129X1/SvJ)
abnormal CD4-positive, alpha beta T cell morphology J:82560
abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology J:82560
enlarged lymph nodes J:82560
enlarged spleen J:82560
increased susceptibility to autoimmune disorder J:82560
skin inflammation J:82560
Foxp3tm1.1Ayr/Y
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
dermatitis J:117743
enlarged spleen J:117743
increased susceptibility to autoimmune disorder J:117743
liver inflammation J:117743
lung inflammation J:117743
lymph node inflammation J:117743
Foxp3tm1.1Ayr/Y
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraTcrb)425Cbn/0

(Not Specified)
immune system phenotype J:97029
Foxp3tm1.1Ayr/Foxp3tm1.1Ayr
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal T cell differentiation J:125405
decreased double-positive T cell number J:125405
dermatitis J:117743
enlarged spleen J:117743
increased susceptibility to autoimmune disorder J:117743
liver inflammation J:117743
lung inflammation J:117743
lymph node inflammation J:117743
thymus hypoplasia J:125405
Foxp3tm1.1Ayr/Foxp3tm1.1Ayr
Mir146tm1.1Bal/Mir146tm1.1Bal

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal lymphocyte physiology J:167922
blepharitis J:167922
conjunctivitis J:167922
decreased interferon-gamma secretion J:167922
dermatitis J:167922
increased regulatory T cell number J:167922
Foxp3tm1.1Mal/Foxp3tm1.1Mal
Lattm1.1Mal/Lattm1.1Mal

(involves: 129S2/SvPas * C57BL/6)
abnormal regulatory T cell physiology J:131351
decreased regulatory T cell number J:131351
thymus hypoplasia J:131351
Foxp3tm1Ayr/Y
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
dermatitis J:97029
enlarged lymph nodes J:97029
enlarged spleen J:97029
increased susceptibility to autoimmune disorder J:97029
Foxp3tm1Ayr/Foxp3tm1Ayr
Foxn1tm3(cre)Nrm/Foxn1+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:125405
Foxp3tm1Ayr/Foxp3tm1Ayr
Tg(Cd4-cre)1Cwi/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal T cell differentiation J:125405
decreased double-positive T cell number J:125405
thymus hypoplasia J:125405
Foxp3tm1Flv/Foxp3+
B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv
Tg(Cd4-cre)1Cwi/?

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
increased regulatory T cell number J:123547
Foxp3tm1Kuch/?
Il6tm1Kopf/Il6tm1Kopf

(involves: 129S2/SvPas * C57BL/6)
abnormal CD4-positive T cell differentiation J:123352
decreased circulating interleukin-6 level J:123352
decreased interleukin-17 secretion J:123352
decreased susceptibility to experimental autoimmune encephalomyelitis J:123352
increased regulatory T cell number J:123352
Foxp3tm1Tch/Y
(C.129X1-Foxp3tm1Tch)
abnormal chemokine level J:117165
abnormal cytokine secretion J:117165
abnormal inflammatory response J:117165
abnormal lymphocyte physiology J:117165
absent regulatory T cells J:117165
dermatitis J:117165
enlarged spleen J:117165
increased activated T cell number J:117165
increased CD4-positive, alpha-beta T cell number J:117165
increased CD8-positive, alpha-beta T cell number J:117165
increased circulating interferon-gamma level J:117165
increased circulating interleukin-4 level J:117165
increased circulating interleukin-5 level J:117165
increased circulating interleukin-6 level J:117165
increased circulating interleukin-10 level J:117165
increased circulating tumor necrosis factor level J:117165
increased eosinophil cell number J:117165
increased IgE level J:117165
increased IgG1 level J:117165
increased leukocyte cell number J:117165
increased lymphocyte cell number J:117165
increased monocyte cell number J:117165
respiratory system inflammation J:117165
Foxp3tm1Tch/Y
(B6.129X1-Foxp3tm1Tch)
abnormal inflammatory response J:117165
dermatitis J:117165
increased eosinophil cell number J:117165
increased IgE level J:117165
increased leukocyte cell number J:117165
increased lymphocyte cell number J:117165
increased monocyte cell number J:117165
respiratory system inflammation J:117165
Foxp3tm1Tch/Y
Stat6tm1Gru/Stat6tm1Gru

(C.129-Stat6tm1Gru Foxp3tm1Tch)
abnormal cytokine secretion J:117165
immune system phenotype J:117165
increased circulating interferon-gamma level J:117165
increased eosinophil cell number J:117165
Foxp3tm2.1(EGFP/cre)Shori/Y
(involves: 129 * C57BL/6)
decreased regulatory T cell number J:234397
Foxp3tm2.1(EGFP/cre)Shori/Y
Pdcd1tm1Hon/Pdcd1tm1Hon

(involves: 129 * 129S2/SvPas * C57BL/6)
enlarged lymph nodes J:234397
enlarged spleen J:234397
increased effector memory T-helper cell number J:234397
increased susceptibility to autoimmune disorder J:234397
lymph node hyperplasia J:234397
pancreas inflammation J:234397
spleen hyperplasia J:234397
Foxp3tm2Ayr/Y
(involves: 129S1/Sv * 129X1/SvJ)
immune system phenotype J:97029
Foxp3tm2Ayr/?
Zap70rps/Zap70rps

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:211510
abnormal double-positive T cell morphology J:211510
abnormal regulatory T cell number J:211510
abnormal T cell differentiation J:211510
decreased CD4-positive, alpha-beta T cell number J:211510
decreased CD8-positive, alpha-beta T cell number J:211510
immune system phenotype J:211510
Foxp3tm2Ayr/Foxp3+
Rnf128tm1Cdon/Rnf128tm1Cdon

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal regulatory T cell physiology J:160681
Foxp3tm2Ayr/Foxp3tm2Ayr
(involves: 129S1/Sv * 129X1/SvJ)
immune system phenotype J:97029
Foxp3tm2Flv/Y
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:118631
abnormal CD8-positive, alpha-beta T cell physiology J:118631
abnormal immune system physiology J:118631
blepharitis J:118631
enlarged lymph nodes J:118631
enlarged spleen J:118631
increased autoantibody level J:118631
Foxp3tm2Tch/Y
(C.129X1-Foxp3tm2Tch)
immune system phenotype J:120713
Foxp3tm2Tch/Foxp3+
(C.129X1-Foxp3tm2Tch)
immune system phenotype J:120713
Foxp3tm3(HBEGF/GFP)Ayr/Foxp3+
Gpr174tm1Cys/Gpr174+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:222307
Foxp3tm3(HBEGF/GFP)Ayr/Foxp3tm3(HBEGF/GFP)Ayr
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:117743
abnormal dendritic cell physiology J:117743
conjunctivitis J:117743
decreased T cell number J:117743
dermatitis J:117743
enlarged spleen J:117743
increased dendritic cell number J:117743
increased susceptibility to autoimmune disorder J:117743
liver inflammation J:117743
lung inflammation J:117743
lymph node inflammation J:117743
Foxp3tm3Tch/Y
(C.129X1-Foxp3tm3Tch)
abnormal CD4-positive, alpha beta T cell morphology J:120636
abnormal CD4-positive, alpha-beta T cell physiology J:120636
abnormal cytokine secretion J:120636
abnormal immune system organ morphology J:120636
abnormal lymphocyte physiology J:120636
abnormal regulatory T cell physiology J:120636
abnormal T cell subpopulation ratio J:120636
colitis J:120636
enlarged lymph nodes J:120636
enlarged spleen J:120636
increased T cell proliferation J:120636
thymus hypoplasia J:120636
Foxp3tm3Tch/Foxp3+
(C.129X1-Foxp3tm3Tch)
abnormal CD4-positive, alpha-beta T cell physiology J:120636
decreased T cell number J:120636
decreased thymocyte number J:120636
increased T cell apoptosis J:120636
Foxp3tm4(YFP/icre)Ayr/Foxp3+
Nr4a2tm1.1Pcn/Nr4a2tm1.1Pcn

(involves: 129S1/Sv * 129X1/SvJ)
abnormal regulatory T cell morphology J:205658
abnormal regulatory T cell physiology J:205658
Foxp3tm4(YFP/icre)Ayr/Foxp3tm4(YFP/icre)Ayr
Ikzf4tm1Djr/Ikzf4tm1Djr

(involves: 129S1/Sv * 129X1/SvJ)
chronic inflammation J:294549
decreased regulatory T cell number J:294549
enlarged lymph nodes J:294549
enlarged spleen J:294549
glomerulonephritis J:294549
granulomatous inflammation J:294549
increased germinal center B cell number J:294549
increased immunoglobulin level J:294549
increased spleen B cell follicle number J:294549
increased spleen germinal center number J:294549
increased susceptibility to experimental autoimmune encephalomyelitis J:294549
increased T cell number J:294549
increased T follicular helper cell number J:294549
small intestinal inflammation J:294549
Foxp3tm5.2Ayr/Foxp3tm5.2Ayr
(involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ)
abnormal gut-associated lymphoid tissue morphology J:156942
abnormal intraepithelial T cell morphology J:156942
abnormal mesenteric lymph node morphology J:156942
abnormal Peyer's patch morphology J:156942
abnormal T cell differentiation J:156942
decreased regulatory T cell number J:156942
increased T cell number J:156942
Foxp3tm6.2Ayr/Foxp3tm6.2Ayr
(involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ)
decreased regulatory T cell number J:156942
Foxp3tm7.2Ayr/Foxp3+
(involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ)
decreased regulatory T cell number J:156942
Foxp3tm7.2Ayr/Foxp3tm7.2Ayr
(involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ)
abnormal regulatory T cell morphology J:156942
decreased regulatory T cell number J:156942
Foxp3tm8Ayr/Y
(B6.129-Foxp3tm8Ayr)
autoimmune response J:157377
Foxq1sa-e1/Foxq1sa-e1
(involves: 101/Rl * C3H/Rl)
abnormal lymphocyte cell number J:75422
Foxq1sa/Foxq1sa
(involves: 101/Rl * C3H/Rl)
impaired natural killer cell mediated cytotoxicity J:7649
Foxq1sa/Foxq1sa
Lystbg/Lystbg

(involves: 101/Rl * C3H/Rl * C57BL/6J * C57BL10/Rl)
enlarged lymph nodes J:5311
increased susceptibility to infection J:5311
interstitial pneumonia J:15166, J:5311
Foxq1sa/Foxq1sa
Lystbg/Lystbg

(involves: 101/Rl * C3H/Rl * C57BL10/Rl)
enlarged spleen J:5311
interstitial pneumonia J:5311
lung inflammation J:5311
Foxr1em1(IMPC)Tcp/Foxr1+
(C57BL/6NCrl-Foxr1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
small spleen J:211773
Foxr1em1(IMPC)Tcp/Foxr1em1(IMPC)Tcp
(C57BL/6NCrl-Foxr1em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
Foxred1em1(IMPC)Bay/Foxred1+
(C57BL/6N-Foxred1em1(IMPC)Bay/Bay)
increased spleen weight J:211773
Fpr1tm1Gao/Fpr1tm1Gao
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal innate immunity J:53354
impaired neutrophil chemotaxis J:53354
increased susceptibility to bacterial infection J:53354
increased susceptibility to bacterial infection induced morbidity/mortality J:53354
Fpr2tm1.1Jimw/Fpr2tm1.1Jimw
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129X1/SvJ)
decreased susceptibility to induced colitis J:197568
Fpr2tm1.2Jimw/Fpr2tm1.2Jimw
(B6.129X1-Fpr2tm1.2Jimw)
abnormal cytokine secretion J:160074
abnormal dendritic cell physiology J:160074
abnormal innate immunity J:160074
decreased dendritic cell number J:160074
decreased IgE level J:160074
decreased IgG1 level J:160074
decreased IgG2b level J:160074
decreased immunoglobulin level J:160074
decreased inflammatory response J:160074
decreased interferon-gamma secretion J:160074
decreased interleukin-2 secretion J:160074
decreased interleukin-4 secretion J:160074
decreased interleukin-5 secretion J:160074
decreased interleukin-13 secretion J:160074
impaired macrophage chemotaxis J:160074
impaired neutrophil chemotaxis J:160074
small lymph nodes J:160074
Fpr2tm1.2Jimw/Fpr2tm1.2Jimw
(involves: 129X1/SvJ)
abnormal dendritic cell chemotaxis J:199611
abnormal dendritic cell physiology J:199611
colitis J:197568
decreased acute inflammation J:197568
decreased dendritic cell number J:199611
Fpr2tm1Rjf/Fpr2tm1Rjf
(involves: 129S/SvEv * C57BL/6)
abnormal neutrophil physiology J:159658
impaired macrophage chemotaxis J:159658
increased acute inflammation J:159658
increased susceptibility to induced arthritis J:159658
fpw/fpw
(involves: C3H/HeJ * C57BL/6J)
decreased circulating interferon-gamma level J:151726
decreased circulating interleukin-1 alpha level J:151726
decreased circulating interleukin-6 level J:151726
increased circulating interleukin-10 level J:151726
increased circulating tumor necrosis factor level J:151726
Frmd3em1(IMPC)J/Frmd3em1(IMPC)J
(C57BL/6NJ-Frmd3em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Frmd8em2Smoc/Frmd8em2Smoc
Tg(Vil1-cre)997Gum/0

(involves: C57BL/6J * SJL)
increased spleen weight J:338904
increased susceptibility to colitis induced morbidity/mortality J:338904
increased susceptibility to induced colitis J:338904
FrylGt(Ayu21-T312)Imeg/FrylGt(Ayu21-T312)Imeg
(B6J.Cg-FrylGt(Ayu21-T312)Imeg)
kidney inflammation J:260667
Fscn1Gt(OST124903)Lex/Fscn1Gt(OST124903)Lex
(B6.129S5-Fscn1Gt(OST124903)Lex)
abnormal dendritic cell chemotaxis J:169408
abnormal dendritic cell physiology J:169408
abnormal Langerhans cell physiology J:169408
Fsd2em1(IMPC)Mbp/Fsd2em1(IMPC)Mbp
(C57BL/6N-Fsd2em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Fshrtm1Saco/Fshrtm1Saco
(involves: 129)
enlarged spleen J:70933
increased pre-B cell number J:65577
Fstl1tm1b(EUCOMM)Hmgu/Fstl1tm1b(EUCOMM)Hmgu
(C57BL/6N-Fstl1tm1b(EUCOMM)Hmgu/H)
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Fth1tm1.1Lck/Fth1tm1.1Lck
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Fth1tm1.1Lck Tg(Mx1-cre)1Cgn)
decreased spleen iron level J:166515
liver inflammation J:166515
Ftl1tm1.1Ruvi/Ftl1tm1.1Ruvi
(involves: 129 * C57BL/6)
abnormal mononuclear phagocyte morphology J:244236
Ftotm1.2Pzg/Ftotm1.2Pzg
(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6)
dermatitis J:166984
Ftotm1.3Pzg/Ftotm1.3Pzg
(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6)
dermatitis J:166984
Fts/Fts+
(involves: C57BL/6 * SJL)
thymus hyperplasia J:20159
Fts/Fts+
(B6.Cg-Fts)
abnormal CD4-positive T cell differentiation J:108193
abnormal T cell morphology J:108193
abnormal T cell physiology J:108193
increased thymocyte number J:108193
thymus hyperplasia J:108193
Fubp1em1(IMPC)Mbp/Fubp1+
(C57BL/6N-Fubp1em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Fubp1tm1.1Dlev/Fubp1tm1.1Dlev
(involves: 129 * C57BL/6)
decreased B cell number J:229985
lymphoid hypoplasia J:229985
spleen hypoplasia J:229985
thymus hypoplasia J:229985
Fundc2tm1Qim/Fundc2tm1Qim
(involves: C57BL/6)
immune system phenotype J:301633
Furintm1Jwmc/Furintm1Jwmc
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal regulatory T cell physiology J:204761
FusGt(U3NeoSV1)HO14Ggh/FusGt(U3NeoSV1)HO14Ggh
(B6.129S2-FusGt(U3NeoSV1)HO14Ggh)
abnormal immunoglobulin level J:60213
decreased B cell number J:60213
decreased lymphocyte cell number J:60213
lymphoid hypoplasia J:60213
small thymus J:60213
Fut2tm1Sdo/Fut2tm1Sdo
(B6.129X1-Fut2tm1Sdo)
increased susceptibility to fungal infection J:90993
Fut4tm1Jbl/Fut4tm1Jbl
(B6.129S2-Fut4tm1Jbl)
impaired leukocyte tethering or rolling J:79397
increased eosinophil cell number J:79397
increased granulocyte number J:79397
increased monocyte cell number J:79397
increased neutrophil cell number J:79397
Fut4tm1Jbl/Fut4tm1Jbl
Fut7tm1Jbl/Fut7tm1Jbl

(B6.129S2-Fut7tm1Jbl Fut4tm1Jbl)
abnormal immune system organ morphology J:79397
abnormal leukocyte migration J:79397
abnormal leukocyte physiology J:79397
abnormal lymph node primary follicle morphology J:79397
abnormal neutrophil physiology J:79397
decreased susceptibility to bacterial infection J:115682
decreased susceptibility to type IV hypersensitivity reaction J:79388
impaired leukocyte tethering or rolling J:79397
increased leukocyte cell number J:79397
increased neutrophil cell number J:79397
lymph node hypoplasia J:79388, J:79397
small lymph nodes J:79397
Fut7tm1Brs/Fut7tm1Brs
(involves: 129 * C57BL/6)
immune system phenotype J:64232
Fut7tm1Jbl/Fut7tm1Jbl
(involves: 129S2/SvPas * C57BL/6J * DBA/2J)
abnormal granulocyte physiology J:35023
abnormal immune system physiology J:35023
abnormal leukocyte adhesion J:35023
abnormal leukocyte migration J:35023
abnormal leukocyte physiology J:35023
abnormal leukocyte tethering or rolling J:35023
abnormal lymph node primary follicle morphology J:35023
impaired neutrophil recruitment J:35023
Fut7tm1Jbl/Fut7tm1Jbl
(B6.129S2-Fut7tm1Jbl)
decreased susceptibility to type IV hypersensitivity reaction J:79388, J:74776
impaired neutrophil recruitment J:79397
Fut8em1(IMPC)Wtsi/Fut8em1(IMPC)Wtsi
(C57BL/6N-Fut8em1(IMPC)Wtsi/Wtsi)
blood in lymph vessels J:239583
Fv4r/Fv4+
(involves: AKR/J * BALB/c * FRG)
decreased susceptibility to Retroviridae infection J:5714, J:5684
Fxntm1Mkn/Fxntm1Mkn
Tg(FXN)YG8Pook/0

(involves: 129/Sv * C57BL/6 * CBA)
brain inflammation J:216422
Fxntm1Mkn/Fxntm1Pand
(involves: 129/Sv * C57BL/6)
brain inflammation J:216422
Fxr1tm1Dln/Fxr1tm1Dln
(involves: 129P2/OlaHsd * C57BL/6)
small spleen J:91191
Fyb1tm1Gak/Fyb1tm1Gak
(B6.129-Fyb1tm1Gak)
immune system phenotype J:112087
Fyb1tm1Gak/Fyb1tm1Gak
(involves: 129S1/Sv * 129X1/SvJ)
abnormal leukocyte adhesion J:111368
abnormal T cell physiology J:126545
decreased interleukin-2 secretion J:111368, J:126545
decreased T cell proliferation J:111368, J:126545
decreased thymocyte number J:111368
Fyntm1Rmp/Fyntm1Rmp
(involves: 129S2/SvPas * C57BL/6)
abnormal T cell activation J:70886
abnormal thymocyte activation J:70886
decreased T cell proliferation J:70886
Fyntm1Rmp/Fyntm1Rmp
(involves: 129S2/SvPas)
decreased gamma-delta T cell number J:37062
decreased T cell number J:37062
Fyntm1Rmp/Fyntm1Rmp
(B6.129S2-Fyntm1Rmp)
abnormal eosinophil physiology J:114287
abnormal interleukin-4 secretion J:114287
decreased IgE level J:114287
decreased interleukin-2 secretion J:114287
increased interleukin-5 secretion J:114287
increased susceptibility to type I hypersensitivity reaction J:114287
Fyntm1Rmp/Fyntm1Rmp
Lcktm1Mak/Lcktm1Mak

(involves: 129S2/SvPas)
abnormal alpha-beta intraepithelial T cell morphology J:112977
abnormal NK T cell number J:37940
absent CD4-positive, alpha-beta T cells J:37940
absent CD8-positive, alpha-beta T cells J:37940
absent T cells J:37062
arrested T cell differentiation J:37062, J:37940
decreased double-positive T cell number J:37940
decreased gamma-delta intraepithelial T cell number J:112977, J:37940
thymus hypoplasia J:37062, J:37940
Fyntm1Sor/Fyntm1Sor
(either: 129S7/SvEvBrd-Fyntm1Sor or (involves: 129S7/SvEvBrd * C57BL/6J))
abnormal immune cell physiology J:2242
abnormal T cell clonal deletion J:2242
abnormal T cell physiology J:2242
abnormal thymocyte activation J:2242
decreased interleukin-2 secretion J:2242
decreased T cell proliferation J:2242
increased IgG2a level J:2242
increased IgM level J:2242
Fyntm1Sor/Fyntm1Sor
(B6.129S7-Fyntm1Sor)
abnormal CD4-positive, alpha-beta T cell physiology J:93886
abnormal NK cell physiology J:187430
abnormal T cell proliferation J:93886
decreased IgE level J:93886
decreased interferon-gamma secretion J:187430
Fyntm1Sor/Fyntm1Sor
(involves: 129S7/SvEvBrd)
abnormal chemokine level J:80658
abnormal macrophage physiology J:80658
Fyntm1Sor/Fyntm1Sor
Lcktm1Litt/Lcktm1.1Litt
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129S7/SvEvBrd * 129X1/SvJ)
abnormal regulatory T cell physiology J:152472
decreased regulatory T cell number J:152472
decreased T cell proliferation J:152472
enlarged lymph nodes J:152472
increased regulatory T cell number J:152472
increased T cell number J:152472
Fyntm1Sor/Fyntm1Sor
Yes1tm1Sor/Yes1tm1Sor

(involves: 129S7/SvEvBrd)
enlarged spleen J:20346
increased spleen white pulp amount J:20346
myeloid hyperplasia J:20346
Fyntm1Yik/Fyntm1Yik
(involves: C57BL/6 * CBA)
abnormal cytokine secretion J:99347
abnormal interleukin secretion J:99347
increased susceptibility to experimental autoimmune uveoretinitis J:99347
increased tumor necrosis factor secretion J:99347
Fyntm1Yik/Fyntm1Yik
Ptk2tm1Lfr/Ptk2+

(involves: 129X1/SvJ * C57BL/6 * CBA)
abnormal T cell differentiation J:110771
decreased double-positive T cell number J:110771
decreased thymocyte number J:110771
thymus cortex atrophy J:110771
Fzd1em1(IMPC)Mbp/Fzd1em1(IMPC)Mbp
(C57BL/6N-Fzd1em1(IMPC)Mbp/MbpMmucd)
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Fzd9tm1Uta/Fzd9tm1Uta
(involves: 129S6/SvEvTac * 129X1/SvJ)
abnormal lymph node medullary cord morphology J:98133
abnormal lymph node morphology J:98133
abnormal spleen marginal zone morphology J:98133
abnormal spleen red pulp morphology J:98133
decreased B cell number J:98133
decreased pre-B cell number J:98133
decreased pro-B cell number J:98133
enlarged lymph nodes J:98133
enlarged spleen J:98133
increased eosinophil cell number J:98133
increased leukocyte cell number J:98133
increased monocyte cell number J:98133
increased neutrophil cell number J:98133
thymus atrophy J:98133
G2e3em1(IMPC)Tcp/G2e3em1(IMPC)Tcp
(C57BL/6NCrl-G2e3em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
G6pc2tm1.1Pesa/G6pc2tm1.1Pesa
(NOD.129S2-G6pc2tm1.1Pesa)
abnormal CD8-positive, alpha beta T cell morphology J:160286
abnormal CD8-positive, alpha-beta T cell physiology J:160286
decreased interferon-gamma secretion J:160286
decreased T cell proliferation J:160286
immune system phenotype J:160286
G6pc3tm1Jyc/G6pc3tm1Jyc
(involves: 129S4/SvJae * C57BL/6)
abnormal neutrophil physiology J:120741
decreased neutrophil cell number J:120741
impaired granulocyte bactericidal activity J:120741
increased granulocyte number J:120741
increased susceptibility to bacterial infection J:120741
G6pd2em1(IMPC)Tcp/G6pd2em1(IMPC)Tcp
(C57BL/6NCrl-G6pd2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Gab2tm1Gsf/Gab2tm1Gsf
(involves: BALB/c)
abnormal response to infection J:122213
decreased susceptibility to Retroviridae infection J:122429
Gab2tm1Hhg/Gab2tm1Hhg
(involves: 129S4/SvJae)
decreased mast cell degranulation J:70424
decreased mast cell number J:70424
decreased susceptibility to type I hypersensitivity reaction J:70424
immune system phenotype J:70424
Gab2tm1Pngr/Gab2tm1Pngr
(B6.Cg-Gab2tm1Pngr)
abnormal osteoclast differentiation J:97515
abnormal osteoclast morphology J:97515
decreased osteoclast cell number J:97515
Gab2tm1Thir/Gab2tm1Thir
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal mast cell differentiation J:75092
abnormal mast cell physiology J:75092
decreased mast cell number J:75092
Gab2tm2.1Thir/Gab2tm2.1Thir
(involves: 129T/SvJcl * C57BL/6Jcl)
immune system phenotype J:178045
Gab2tm3.1Thir/Gab2tm3.1Thir
(involves: 129T/SvJcl * C57BL/6Jcl)
decreased mast cell degranulation J:178045
decreased mast cell number J:178045
decreased susceptibility to type I hypersensitivity reaction J:178045
immune system phenotype J:178045
Gab2tm4.1Thir/Gab2tm4.1Thir
(involves: 129T/SvJcl * C57BL/6Jcl)
decreased mast cell degranulation J:178045
decreased mast cell number J:178045
decreased susceptibility to type I hypersensitivity reaction J:178045
immune system phenotype J:178045
Gab3em1Khoe/Gab3em1Khoe
(C57BL/6-Gab3em1Khoe)
abnormal mature NK cell morphology J:291290
abnormal NK cell physiology J:291290
abnormal uterine NK cell morphology J:291290
decreased NK cell number J:291290
immune system phenotype J:291290
Gab3m1Khoe/Gab3m1Khoe
(C57BL/6-Gab3m1Khoe)
abnormal mature NK cell morphology J:291290
abnormal NK cell physiology J:291290
abnormal uterine NK cell morphology J:291290
decreased NK cell number J:291290
immune system phenotype J:291290
Gabarapl2tm1b(EUCOMM)Hmgu/Gabarapl2+
(C57BL/6N-Gabarapl2tm1b(EUCOMM)Hmgu/H)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
GabpaGt(XH074)Byg/GabpaGt(XH074)Byg
(involves: 129P2/OlaHsd * C57BL/6)
decreased thymocyte number J:92671
small thymus J:92671
Gabpb1tm1Hhx/Gabpb1tm1Hhx
(involves: 129 * C57BL/6)
immune system phenotype J:137300
Gabpb2Gt(RRJ488)Byg/Gabpb2Gt(RRJ488)Byg
(involves: 129P2/OlaHsd)
increased B cell proliferation J:141846
increased IgG1 level J:141846
increased IgM level J:141846
increased spleen germinal center number J:141846
Gabra5em1(IMPC)Ccpcz/Gabra5em1(IMPC)Ccpcz
(C57BL/6N-Gabra5em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small spleen J:211773
Gad2tm1Miya/Gad2tm1Miya
(NOD.129P2-Gad2tm1Miya)
pancreas inflammation J:88785
Gadd45atm1Ajf/Gadd45atm1Ajf
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129X1/SvJ * C57BL/6))
abnormal lymphopoiesis J:76041
decreased basophil cell number J:76041
decreased eosinophil cell number J:76041
decreased leukocyte cell number J:76041
decreased lymphocyte cell number J:76041
glomerulonephritis J:76041
increased anti-double stranded DNA antibody level J:76041
increased anti-histone antibody level J:76041
increased anti-single stranded DNA antibody level J:76041
increased autoantibody level J:76041
increased IgG1 level J:76041
increased IgM level J:76041
increased inflammatory response J:76041
increased T cell number J:76041
increased T cell proliferation J:76041
increased thymocyte number J:57882
increased thymus weight J:57882
Gadd45btm1Flv/Gadd45btm1Flv
(involves: 129S6/SvEvTac)
abnormal CD4-positive, alpha-beta T cell physiology J:87396
abnormal dendritic cell physiology J:87396
abnormal T-helper 1 cell differentiation J:87396
abnormal T-helper 1 physiology J:87396
abnormal T-helper 2 physiology J:87396
decreased interferon-gamma secretion J:87396
decreased interleukin-2 secretion J:87396
decreased interleukin-4 secretion J:87396
decreased interleukin-6 secretion J:87396
decreased interleukin-12 secretion J:87396
Gadd45btm1Flv/Gadd45btm1Flv
(B6.129S6-Gadd45btm1Flv)
abnormal T-helper 1 physiology J:118837
glomerulonephritis J:118837
increased interferon-gamma secretion J:118837
increased susceptibility to experimental autoimmune encephalomyelitis J:118837
increased T cell proliferation J:118837
spleen hyperplasia J:118837
Gadd45btm1Flv/Gadd45btm1Flv
Gadd45gtm1Flv/Gadd45gtm1Flv

(involves: 129S1/Sv * 129S6/SvEvTac)
abnormal T-helper 1 cell differentiation J:87396
Gadd45btm1Flv/Gadd45btm1Flv
Gadd45gtm1Flv/Gadd45gtm1Flv

(involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6)
glomerulonephritis J:118837
increased anti-double stranded DNA antibody level J:118837
increased anti-histone antibody level J:118837
increased IgG1 level J:118837
increased IgM level J:118837
increased mature B cell number J:118837
increased memory T cell number J:118837
spleen hyperplasia J:118837
Gadd45gtm1Flv/Gadd45gtm1Flv
(involves: 129S1/Sv)
abnormal NK cell physiology J:87396
abnormal T-helper 1 cell differentiation J:87396
abnormal T-helper 1 physiology J:69475
abnormal type IV hypersensitivity reaction J:69475
decreased interferon-gamma secretion J:87396, J:69475
Gadd45gtm1Jni/Gadd45gtm1Jni
(involves: 129P2/OlaHsd)
immune system phenotype J:68832
Galctm1Wngr/Galctm1Wngr
(involves: 129S2/SvPas)
abnormal immune system physiology J:78691
Galctwi-5J/Galctwi-5J
(BXD32/TyJ-Galctwi-5J/J)
abnormal leukocyte morphology J:199132
Galctwi/Galctwi
(B6.CE-Galctwi/J)
abnormal microglial cell morphology J:108359
abnormal osteoclast physiology J:165361
Galctwi/Galctwi
(involves: C57BL/6J * CE/J)
abnormal macrophage morphology J:6390
Galctwi/Galctwi
(involves: CE/J)
CNS inflammation J:78223
Galctwi/Galctwi
Glb1tm1Adz/Glb1+

(involves: 129P2/OlaHsd * C57BL/6J * CE/J)
immune system phenotype J:63197
Galctwi/Galctwi
Glb1tm1Adz/Glb1tm1Adz

(involves: 129P2/OlaHsd * C57BL/6J * CE/J)
abnormal macrophage physiology J:63197
enlarged spleen J:63197
Galctwi/Galctwi
Il6+/?

(involves: 129S2/SvPas * C57BL/6J * CE/J)
abnormal tumor necrosis factor level J:56656
Galctwi/Galctwi
Il6tm1Kopf/Il6tm1Kopf

(involves: 129S2/SvPas * C57BL/6J * CE/J)
abnormal tumor necrosis factor level J:56656
Galnt1tm1.1Jxm/Galnt1tm1.1Jxm
(B6NHsd.Cg-Galnt1tm1.1Jxm)
abnormal immune system physiology J:128982
decreased B cell number J:128982
decreased basophil cell number J:128982
decreased eosinophil cell number J:128982
decreased germinal center B cell number J:128982
decreased IgG level J:128982
decreased leukocyte cell number J:128982
decreased plasma cell number J:128982
decreased spleen germinal center number J:128982
decreased T cell number J:128982
impaired leukocyte tethering or rolling J:128982
increased lymphocyte cell number J:128982
lymph node hypoplasia J:128982
Galnt3tm1.1Cfg/Galnt3tm1.1Cfg
(involves: C57BL/6)
decreased monocyte cell number J:217719
Galnt13em1(IMPC)Mbp/Galnt13em1(IMPC)Mbp
(C57BL/6N-Galnt13em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Galnt18tm1b(KOMP)Wtsi/Galnt18tm1b(KOMP)Wtsi
(C57BL/6N-Galnt18tm1b(KOMP)Wtsi/Wtsi)
increased NK cell number J:211773
Galr1em1(IMPC)H/Galr1em1(IMPC)H
(C57BL/6N-Galr1em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased eosinophil cell number J:211773
Galr2Gt(OST105469)Lex/Galr2Gt(OST105469)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased B cell number J:103485
increased T cell number J:103485
GaltGt(E285B04)Wrst/GaltGt(E285B04)Wrst
(involves: 129P2/OlaHsd * C57BL/6J)
brain inflammation J:234753
liver inflammation J:234753
Gapttm1.1Wz/Gapttm1.1Wz
(Not Specified)
immune system phenotype J:138146
increased B cell proliferation J:138146
increased IgG2b level J:138146
increased IgG3 level J:138146
increased IgM level J:138146
increased marginal zone B cell number J:138146
Gapvd1em1(IMPC)Mbp/Gapvd1+
(C57BL/6N-Gapvd1em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Garem1em1(IMPC)Mbp/Garem1em1(IMPC)Mbp
(C57BL/6N-Garem1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Garin1aem1(IMPC)Ccpcz/Garin1aem1(IMPC)Ccpcz
(C57BL/6N-Garin1aem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Garin1bem1(IMPC)Ccpcz/Garin1bem1(IMPC)Ccpcz
(C57BL/6N-Garin1bem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Garin2em1(IMPC)Ccpcz/Garin2em1(IMPC)Ccpcz
(C57BL/6N-Garin2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Gars1em1(IMPC)Tcp/Gars1+
(C57BL/6NCrl-Gars1em1(IMPC)Tcp/Tcp)
small spleen J:211773
Gas2l2tm1a(KOMP)Wtsi/Gas2l2tm1a(KOMP)Wtsi
(C57BL/6N-Gas2l2tm1a(KOMP)Wtsi/Wtsi)
abnormal thymus topology J:239583
Gas6tm1Hiar/Gas6tm1Hiar
(B6.129P2-Gas6tm1Hiar)
immune system phenotype J:112430
Gasa1BALB/cCrSlc/Gasa1BALB/cCrSlc
(involves: BALB/cCrSlc * C57BL/6)
stomach inflammation J:54699
Gasa1BALB/cCrSlc/Gasa1C57BL/6
(involves: BALB/cCrSlc * C57BL/6)
stomach inflammation J:54699
Gasa2BALB/cCrSlc/Gasa2BALB/cCrSlc
(involves: BALB/cCrSlc * C57BL/6)
stomach inflammation J:54699
Gasa2BALB/cCrSlc/Gasa2BALB/cCrSlc
Gasa4BALB/cCrSlc/Gasa4C57BL/6

(involves: BALB/cCrSlc * C57BL/6)
stomach inflammation J:75277
Gasa2BALB/cCrSlc/Gasa2C57BL/6
(involves: BALB/cCrSlc * C57BL/6)
stomach inflammation J:54699
Gasa3BALB/cCrSlc/Gasa3C57BL/6
(involves: BALB/cCrSlc * C57BL/6)
stomach inflammation J:75277
Gasa4BALB/cCrSlc/Gasa4C57BL/6
(involves: BALB/cCrSlc * C57BL/6)
stomach inflammation J:75277
Gasttm1Lcs/Gasttm1Lcs
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
stomach inflammation J:97527
Gata1Plt13/Gata1+
(BALB/c-Gata1Plt13)
abnormal myelopoiesis J:113720
abnormal thrombopoiesis J:113720
enlarged spleen J:113720
increased spleen weight J:113720
Gata1tm1Mym/Y
Tg(Gata1*)#Mym/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2J)
increased leukocyte cell number J:158252
Gata1tm1Mym/Y
Tg(Gata1*V205G)1Mym/0

(involves: C57BL/6 * DBA/2)
abnormal mononuclear cell morphology J:89054
abnormal thrombopoiesis J:89054
Gata1tm1Mym/Gata1+
(involves: 129P2/OlaHsd)
decreased spleen red pulp amount J:88685
decreased spleen white pulp amount J:88685
enlarged spleen J:88685
pale spleen J:88685
Gata1tm1Mym/Gata1tm1Mym
Tg(Gata1*)#Mym/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2J)
increased leukocyte cell number J:158252
Gata1tm1Sho/Y
Tg(Gata1*)#Mym/0

(involves: 129S4/SvJae * C57BL/6 * DBA/2J)
increased leukocyte cell number J:158252
Gata1tm1Sho/Gata1+
(involves: 129S4/SvJae * C57BL/6)
decreased eosinophil cell number J:88711
Gata1tm1Sho/Gata1tm1Sho
Tg(Gata1*)#Mym/0

(involves: 129S4/SvJae * C57BL/6 * DBA/2J)
increased leukocyte cell number J:158252
Gata1tm2Sho/Y
(involves: 129S4/SvJae * C57BL/6 * CD-1)
abnormal spleen morphology J:78348
abnormal spleen red pulp morphology J:78540
decreased lymphocyte cell number J:78348
enlarged spleen J:78348, J:78540
increased neutrophil cell number J:78348
increased splenocyte number J:78540
Gata1tm2Sho/Gata1tm2Sho
(involves: 129S4/SvJae * C57BL/6 * CD-1)
abnormal spleen morphology J:78348
abnormal spleen red pulp morphology J:78540
decreased lymphocyte cell number J:78348
enlarged spleen J:78348, J:78540
increased neutrophil cell number J:78348
increased splenocyte number J:78540
Gata1tm2Sho/Gata1tm2Sho
(involves: 129S4/SvJae)
increased osteoclast cell number J:111270
Gata1tm6Sho/Y
(involves: 129S1/Sv)
decreased eosinophil cell number J:88711
enlarged spleen J:88711
Gata1tm6Sho/Gata1tm6Sho
(involves: 129S1/Sv)
decreased eosinophil cell number J:88711
Gata1tm6Sho/Gata1tm6Sho
(involves: 129S1/Sv * BALB/c)
abnormal leukocyte cell number J:115273
decreased circulating interleukin-4 level J:115273
decreased circulating interleukin-13 level J:115273
decreased eosinophil cell number J:115273
decreased lymphocyte cell number J:115273
increased neutrophil cell number J:115273
Gata1tm6Sho/Gata1tm6Sho
(C.129S1-Gata1tm6Sho)
autoimmune response J:182213
Gata3tm1.1Mbu/Gata3tm1.1Mbu
(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal humoral immune response J:123631
decreased interleukin-4 secretion J:123631
increased interferon-gamma secretion J:123631
Gata3tm1Iho/Gata3tm1Iho
Il13tm1(YFP/cre)Lky/Il13+

(involves: 129S4/SvJae)
decreased eosinophil cell number J:178986
increased susceptibility to parasitic infection J:178986
Gata3tm1Iho/Gata3tm1Iho
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal T cell differentiation J:86996
decreased CD4-positive, alpha-beta T cell number J:86996
Gata3tm1Iho/Gata3tm1Iho
Tg(Cd4-cre)1Cwi/0
Tg(DO11.10)10Dlo/0

(involves: BALB/c * C3H * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:86996
Gata3tm1Iho/Gata3tm1Iho
Tg(DO11.10)10Dlo/0
Tg(Lck-cre)1Cwi/0

(involves: BALB/c * C3H * C57BL/6)
arrested T cell differentiation J:86996
decreased CD4-positive, alpha-beta T cell number J:86996
decreased CD8-positive, alpha-beta T cell number J:86996
decreased double-positive T cell number J:86996
small thymus J:86996
Gata3tm1Iho/Gata3tm1Iho
Tg(Lck-cre)1Cwi/0

(involves: BALB/c)
abnormal CD8-positive, alpha-beta T cell number J:86996
abnormal T cell subpopulation ratio J:86996
arrested T cell differentiation J:86996
decreased CD4-positive, alpha-beta T cell number J:86996
decreased double-positive T cell number J:86996
decreased thymocyte number J:86996
increased T cell apoptosis J:86996
small thymus J:86996
Gata3tm1Jeng/Gata3tm1Jeng
(involves: 129S7/SvEvBrd)
abnormal immune system organ morphology J:62552
Gata3tm1Jfz/Gata3tm1Jfz
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-cre)1Cwi/0
Tg(Tcra5CC7,Tcrb5CC7)IWep/0

(involves: 129S/SvEv * C57BL/6 * DBA/2)
abnormal T cell differentiation J:141145
Gata3tm1Jfz/Gata3tm1Jfz
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:93538
abnormal T cell differentiation J:141145
decreased CD4-positive, alpha-beta T cell number J:141145
decreased interleukin-13 secretion J:172134
Gata3tm1Jfz/Gata3tm1Jfz
Tg(Tnfrsf4-cre)1Nik/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:93538
decreased IgE level J:93538
decreased T-helper 2 cell number J:93538
increased susceptibility to parasitic infection J:93538
increased T-helper 1 cell number J:93538
Gata3tm1Jml/Gata3tm1Jml
(involves: 129S/SvEv * C57BL/6)
abnormal immune system cell morphology J:37093
Gata3tm2Jeng/Gata3tm2Jeng
(Not Specified)
abnormal double-positive T cell morphology J:155686
abnormal T cell differentiation J:155686
abnormal T cell number J:155686
decreased double-negative T cell number J:155686
decreased gamma-delta T cell number J:155686
decreased thymocyte number J:155686
Gata3tm3Gsv/Gata3tm3Gsv
Tg(KRT14-cre)8Brn/0

(involves: 129P2/OlaHsd * FVB/N)
decreased T cell number J:117058
Gata5tm1.2Nemr/Gata5tm1.2Nemr
(Not Specified)
kidney inflammation J:227997
Gata5tm1Eno/Gata5tm1Eno
(involves: 129S6/SvEvTac * C57BL/6)
urethritis J:63036
vaginal inflammation J:63036
Gatad2btm1b(EUCOMM)Hmgu/Gatad2b+
(C57BL/6N-Gatad2btm1b(EUCOMM)Hmgu/Ics)
increased monocyte cell number J:211773
Gatmem1Btlr/Gatmem1Btlr
(C57BL/6J-Gatmem1Btlr)
immune system phenotype J:252049
increased susceptibility to induced colitis J:252049
Gatmem1Btlr/Gatmm1Btlr
(C57BL/6J-Gatmem1Btlr/Gatmm1Btlr)
increased susceptibility to induced colitis J:252049
Gatmm1Btlr/Gatm+
(C57BL/6J-Gatmm1Btlr)
increased susceptibility to induced colitis J:252049
Gatmm1Btlr/Gatmm1Btlr
(C57BL/6J-Gatmm1Btlr)
increased susceptibility to induced colitis J:252049
Gba1tm1.1Pmis/Gba1tm1.1Pmis
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal circulating chemokine level J:167081
abnormal circulating cytokine level J:167081
abnormal T cell differentiation J:167081
abnormal thymus morphology J:167081
decreased circulating interleukin-1 alpha level J:167081
decreased circulating interleukin-1 beta level J:167081
decreased circulating interleukin-6 level J:167081
decreased circulating tumor necrosis factor level J:167081
decreased double-positive T cell number J:167081
enlarged spleen J:167081
increased circulating interferon-gamma level J:167081
increased circulating interleukin-2 level J:167081
increased circulating interleukin-3 level J:167081
increased circulating interleukin-9 level J:167081
increased circulating interleukin-10 level J:167081
increased circulating interleukin-13 level J:167081
spleen hyperplasia J:167081
Gba1tm1.1Pmis/Gba1tm1.2Pmis
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal circulating chemokine level J:167081
abnormal circulating cytokine level J:167081
abnormal T cell differentiation J:167081
abnormal thymus morphology J:167081
decreased circulating interleukin-1 alpha level J:167081
decreased circulating interleukin-1 beta level J:167081
decreased circulating interleukin-6 level J:167081
decreased circulating tumor necrosis factor level J:167081
decreased double-positive T cell number J:167081
enlarged spleen J:167081
increased circulating interferon-gamma level J:167081
increased circulating interleukin-2 level J:167081
increased circulating interleukin-3 level J:167081
increased circulating interleukin-9 level J:167081
increased circulating interleukin-10 level J:167081
increased circulating interleukin-13 level J:167081
spleen hyperplasia J:167081
Gba1tm1Clk/Gba1tm1.1Clk
Tg(Tek-cre)12Flv/0

(involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J)
abnormal macrophage morphology J:117763
abnormal spleen morphology J:117763
increased spleen weight J:117763
Gba1tm1Karl/Gba1tm1.1Karl
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal immune system organ morphology J:113751
abnormal response to transplant J:113751
abnormal spleen morphology J:113751
enlarged spleen J:113751
intermingled spleen red and white pulp J:113751
Gba1tm1Karl/Gba1tm1Karl
Tg(Nes-cre)1Kln/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
abnormal microglial cell morphology J:127108
Gba1tm1Nsb/Gba1tm1Nsb
(involves: 129S/SvEv * C57BL/6)
abnormal macrophage morphology J:1100
Gba1tm1Rlp/Gba1tm1Rlp
(involves: 129S4/SvJae * C57BL/6)
abnormal inflammatory response J:76409
abnormal Kupffer cell morphology J:76409
abnormal lymph node morphology J:76409
abnormal macrophage morphology J:76409
abnormal spleen physiology J:76409
decreased leukocyte cell number J:76409
increased IgG level J:76409
increased spleen weight J:76409
liver inflammation J:76409
lung inflammation J:76409
lymph node inflammation J:76409
skin inflammation J:76409
Gba1tm2Ggb/Gba1tm1Nsb
(involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6)
abnormal spleen morphology J:86334
Gba1tm2Ggb/Gba1tm2Ggb
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal spleen morphology J:86334
Gba1tm2Karl/Gba1tm2Karl
Tg(KRT14-cre)8Brn/?

(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
abnormal macrophage morphology J:127108
Gba1tm3Ggb/Gba1tm1Nsb
(involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6)
abnormal spleen morphology J:86334
Gba1tm3Ggb/Gba1tm3Ggb
(involves: 129S5/SvEvBrd)
abnormal spleen morphology J:86334
Gba1tm4Ggb/Gba1tm1Nsb
(involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6)
abnormal spleen morphology J:86334
Gba1tm4Ggb/Gba1tm4Ggb
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal spleen morphology J:86334
Gbp2-pstm1.1Ktak/Gbp2-pstm1.1Ktak
(involves: C57BL/6)
immune system phenotype J:187397
Gbp2-pstm1.1Ktak/Gbp2-pstm1.1Ktak
Gbp5tm1Ktak/Gbp5tm1Ktak

(involves: C57BL/6)
immune system phenotype J:187397
Gbp2tm1.1Kpf/Gbp2tm1.1Kpf
(involves: 129P2/OlaHsd)
immune system phenotype J:192526
increased susceptibility to parasitic infection J:192526
increased susceptibility to parasitic infection induced morbidity/mortality J:192526
Gbp2btm1Tigm/Gbp2btm1Tigm
(B6.129S5-Gbp2btm1Tigm/Jdmm)
abnormal macrophage physiology J:172364
immune system phenotype J:172364
increased susceptibility to bacterial infection J:172364
increased susceptibility to bacterial infection induced morbidity/mortality J:172364
Gbp5tm1Tigm/Gbp5tm1Tigm
(B6.Cg-Gbp5tm1Tigm)
decreased circulating interleukin-1 beta level J:183942
decreased circulating interleukin-18 level J:183942
decreased interleukin-1 beta secretion J:183942
decreased interleukin-18 secretion J:183942
impaired neutrophil recruitment J:183942
increased susceptibility to bacterial infection J:183942
Gbp7tm1Ddgd/Gbp7tm1Ddgd
(B6.129P2-Gbp7tm1Ddgd)
increased susceptibility to bacterial infection J:314959
increased susceptibility to bacterial infection induced morbidity/mortality J:314959
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt
Fgf8tm1.4Mrt/Fgf8+

(B6.129-Gbx2tm1.1Mrt Fgf8tm1.4Mrt)
abnormal thymus development J:100584
Gcatm1Roes/Gcatm1Roes
(involves: 129P2/OlaHsd * 129S2/SvPas)
decreased susceptibility to endotoxin shock J:81436
Gcc2em1Cya/Gcc2em1Cya
(C57BL/6J-Gcc2em1Cya)
increased autoantibody level J:346915
Gcn1em1(IMPC)J/Gcn1+
(C57BL/6NJ-Gcn1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Gcnt1tm1Jxm/Gcnt1tm1Jxm
(involves: 129/Sv * C57BL/6)
abnormal acute inflammation J:86387
abnormal B cell differentiation J:86387
abnormal immune system cell morphology J:86387
abnormal immune system physiology J:86387
abnormal inflammatory response J:86387
increased leukocyte cell number J:86387
increased neutrophil cell number J:86387
Gcnt1tm1Jxm/Gcnt1tm1Jxm
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal leukocyte migration J:113195
impaired leukocyte tethering or rolling J:113195
Gcnt2tm1Tmu/Gcnt2tm1Tmu
(involves: 129S2/SvPas * C57BL/6)
decreased B cell number J:100533
Gcnt3tm1.1Jxm/Gcnt3tm1.1Jxm
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased IgA level J:149909
decreased IgG1 level J:149909
decreased IgG2a level J:149909
decreased IgG2b level J:149909
increased susceptibility to induced colitis J:149909
Gcnt4tm1.1Jxm/Gcnt4tm1.1Jxm
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
increased neutrophil cell number J:149909
Gcsamtm1.1Rsky/Gcsamtm1.1Rsky
(involves: BALB/cJ * C57BL/6)
decreased Peyer's patch number J:125784
immune system phenotype J:125784
small Peyer's patches J:125784
GcsfisC57BL/6J/?
(involves: C57BL/6J * DBA/2J)
enlarged spleen J:61462
GcsfisC57BL/6J/GcsfisC57BL/6J
(B6.SJL-Ptprca Pepcb/BoyJ)
enlarged spleen J:61462
Gdatm1a(KOMP)Wtsi/Gdatm1a(KOMP)Wtsi
(C57BL/6N-Gdatm1a(KOMP)Wtsi/Wtsi)
decreased T-helper cell number J:211773
increased effector memory T-helper cell number J:211773
Gdap1tm2b(KOMP)Wtsi/Gdap1tm2b(KOMP)Wtsi
(C57BL/6N-Gdap1tm2b(KOMP)Wtsi/Ucd)
abnormal thymus morphology J:211773
small thymus J:211773
Gdf1tm1Sjl/Gdf1tm1Sjl
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal spleen morphology J:60755
Gdf2tm1Lex/Gdf2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal lymphatic vessel morphology J:222016
lymphangiectasis J:222016
Gdf5em1(IMPC)H/Gdf5em1(IMPC)H
(C57BL/6NTac-Gdf5em1(IMPC)H/H)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
Gdf6em1(IMPC)Ccpcz/Gdf6+
(C57BL/6NCrl-Gdf6em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Gdf11tm1Sjl/Gdf11tm1Sjl
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal spleen morphology J:94455
Gdnftm1Lmgd/Gdnf+
(B6.129-Gdnftm1Lmgd)
tubulointerstitial nephritis J:103081
Gdnftm1Rosl/Gdnftm1Rosl
(involves: 129S2/SvPas)
abnormal spleen red pulp morphology J:33808
Gdpd3m1Anu/Gdpd3m1Anu
(C57BL/6NCrlAnu-Gdpd3m1Anu)
immune system phenotype J:104190
Gdpd5tm1b(EUCOMM)Hmgu/Gdpd5+
(C57BL/6N-Gdpd5tm1b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
Gemin5em1(IMPC)H/Gemin5+
(C57BL/6N-Gemin5em1(IMPC)H/H)
increased large unstained cell number J:211773
Gfaptm1Pkny/Gfaptm1Pkny
Ppt1tm1Hof/Ppt1tm1Hof
Vimtm1Cba/Vimtm1Cba

(involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac * C57BL/6)
abnormal cytokine level J:177265
brain inflammation J:177265
Gfaptm1Pkny/Gfaptm1Pkny
Vimtm1Cba/Vimtm1Cba

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
decreased inflammatory response J:123278
Gfertm1.1Crg/Gfertm1.1Crg
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129 * C57BL/6 * DBA)
liver inflammation J:227242
Gfi1Gen/Gfi1+
(C57BL/6J-Gfi1Gen)
abnormal myelopoiesis J:182679
abnormal NK cell differentiation J:182679
abnormal NK cell physiology J:182679
absent neutrophils J:182679
decreased NK cell degranulation J:182679
immune system phenotype J:182679
Gfi1tm1.1Wep/Gfi1tm1.1Wep
(B6.129-Gfi1tm1.1Wep)
arrested T cell differentiation J:117105
decreased B cell number J:117105
small thymus J:117105
thymus hypoplasia J:117105
Gfi1tm1Tmo/Gfi1tm1Tmo
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal cytokine secretion J:75143
abnormal granulocyte differentiation J:75143
abnormal monocyte differentiation J:75143
abnormal myelopoiesis J:75143
abnormal T cell differentiation J:75143
decreased B cell number J:75143
decreased granulocyte number J:75143
decreased lymphocyte cell number J:75143
decreased neutrophil cell number J:75143
decreased T cell number J:75143
decreased thymocyte number J:75143
increased interleukin-1 beta secretion J:75143
increased interleukin-10 secretion J:75143
increased susceptibility to endotoxin shock J:75143
increased tumor necrosis factor secretion J:75143
Gfi1tm1Tmo/Gfi1tm1Tmo
(involves: 129S1/Sv * 129X1/SvJ)
decreased B cell number J:192927
decreased granulocyte number J:192927
decreased neutrophil cell number J:192927
decreased thymocyte number J:192927
increased monocyte cell number J:192927
Gfi1tm1Wep/Gfi1tm1Wep
(B6.129-Gfi1tm1Wep)
abnormal T cell proliferation J:117105
Gfi1tm1Wep/Gfi1tm1Wep
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal T cell proliferation J:117105
abnormal T cell subpopulation ratio J:117105
abnormal T-helper 2 physiology J:117105
Gfi1tm2Tmo/Gfi1tm2Tmo
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal T cell differentiation J:93337
decreased neutrophil cell number J:93337
decreased thymocyte number J:93337
Gfi1tm3(Gfib1)Tmo/Gfi1tm3(Gfib1)Tmo
(involves: 129S1/Sv * 129X1/SvJ)
abnormal monocyte morphology J:116870
decreased granulocyte number J:116870
Gfi1tm4Tmo/Gfi1tm4Tmo
(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymphopoiesis J:116870
abnormal monocyte morphology J:116870
abnormal neutrophil morphology J:116870
abnormal T cell differentiation J:116870
decreased double-negative T cell number J:116870
decreased lymphocyte cell number J:116870
decreased neutrophil cell number J:116870
decreased thymocyte number J:116870
Gfi1tm5.1(GFI1*)Tmo/Gfi1+
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA)
myeloid hyperplasia J:192927
Gfi1tm5.1(GFI1*)Tmo/Gfi1tm5.1(GFI1*)Tmo
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
increased monocyte cell number J:192927
Gfi1tm5.1(GFI1*)Tmo/Gfi1tm5.1(GFI1*)Tmo
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA)
myeloid hyperplasia J:192927
Gfi1tm6.1(GFI1)Tmo/Gfi1tm6.1(GFI1)Tmo
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA)
myeloid hyperplasia J:192927
Gfi1btm1b(EUCOMM)Hmgu/Gfi1b+
(C57BL/6N-Gfi1btm1b(EUCOMM)Hmgu/H)
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Gfi1btm2Tmo/Gfi1btm2Tmo
Tg(Mx1-cre)1Cgn/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
increased splenocyte number J:167416
Gfra1tm1Rosl/Gfra1tm1Rosl
(either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1))
decreased Peyer's patch number J:120816
Gfustm1Jbl/Gfustm1Jbl
(involves: 129S2/SvPas * C57BL/6J)
increased leukocyte cell number J:82239
increased neutrophil cell number J:82239
large intestinal inflammation J:82239
Ggcttm1.2Smoc/Ggcttm1.2Smoc
(involves: C57BL/6J)
enlarged spleen J:322242
increased spleen red pulp amount J:322242
Gghem1(IMPC)Tcp/Gghem1(IMPC)Tcp
(C57BL/6N-Gghem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
ggld/ggld
(MRL/MpJ-Faslpr/J-ggld)
decreased IgG1 level J:14258
Ggps1tm1b(EUCOMM)Wtsi/Ggps1+
(C57BL/6N-Ggps1tm1b(EUCOMM)Wtsi/Ieg)
increased leukocyte cell number J:211773
Ggt1dwg/Ggt1dwg
((STOCK Pou1f1dw x T(8;16)17H)F1)
decreased spleen red pulp amount J:14281
increased osteoclast cell number J:14281
Ggt5tm1Mwl/Ggt5tm1Mwl
(involves: 129S7/SvEvBrd * C57BL/6J)
decreased acute inflammation J:77691
Ggta1tm1Jbl/Ggta1+
Ightm1Jiac/Igh+
Igktm1Jiac/Igktm1Jiac

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6)
decreased mature B cell number J:133032
Ggta1tm1Jbl/Ggta1+
Ightm1Jiac/Ightm1Jiac
Igktm1Jiac/Igk+

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6)
decreased mature B cell number J:133032
Ggta1tm1Jbl/Ggta1+
Ightm1Jiac/Ightm1Jiac
Igktm1Jiac/Igktm1Jiac

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6)
abnormal B cell physiology J:133032
abnormal B cell selection J:133032
decreased mature B cell number J:133032
Ggta1tm1Jbl/Ggta1tm1Jbl
(involves: 129S2/SvPas)
abnormal humoral immune response J:113488, J:90851
abnormal immunoglobulin level J:113488
abnormal response to transplant J:90851
decreased IgG level J:90851
increased IgM level J:90851
Ghtm1.1(KOMP)Vlcg/Ghtm1.1(KOMP)Vlcg
(C57BL/6N-Ghtm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
decreased spleen weight J:211773
decreased thymus weight J:211773
small spleen J:211773
Ghrtm1Arge/Ghrtm1Arge
(involves: 129S/SvEv * C57BL/6J)
small spleen J:66913
Ghrtm1c(KOMP)Wtsi/Ghrtm1c(KOMP)Wtsi
Tg(Fabp4-cre)1Rev/0

(involves: C57BL/6N)
decreased spleen weight J:206358
increased circulating interleukin-6 level J:206358
Ghrtm1Jjk/Ghrtm1Jjk
(involves: 129P2/OlaHsd * BALB/c)
decreased spleen weight J:60207
decreased susceptibility to autoimmune diabetes J:59132
Ghrtm2Mwat/Ghrtm2Mwat
(involves: 129X1/SvJ * C57BL)
small spleen J:95149
Ghrhtm1Salv/Ghrhtm1Salv
(involves: 129 * C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:177054
Ghrhrlit/Ghrhrlit
(C57BL/6J-Ghrhrlit)
decreased susceptibility to experimental autoimmune encephalomyelitis J:85381
Gigyf2tm1b(EUCOMM)Wtsi/Gigyf2tm1b(EUCOMM)Wtsi
(C57BL/6N-Gigyf2tm1b(EUCOMM)Wtsi/Bay)
decreased eosinophil cell number J:211773
increased spleen weight J:211773
Gimap1m1Btlr/Gimap1m1Btlr
(C57BL/6J-Gimap1m1Btlr)
decreased B cell number J:267546
decreased B-1 B cell number J:267546
decreased CD8-positive, alpha-beta T cell number J:267546
decreased IgD level J:267546
increased CD4-positive, alpha-beta T cell number J:267546
increased IgM level J:267546
Gimap1tm1.1Gwb/Gimap1tm1.1Gwb
Tg(CD2-icre)4Kio/0

(involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca)
abnormal CD4-positive, alpha-beta T cell physiology J:160782
abnormal CD8-positive, alpha-beta T cell physiology J:160782
decreased B cell number J:160782
decreased B-1a cell number J:160782
decreased B-1b cell number J:160782
decreased B-2 B cell number J:160782
decreased CD4-positive, alpha-beta T cell number J:160782
decreased CD8-positive, alpha-beta T cell number J:160782
decreased follicular B cell number J:160782
decreased lymphocyte cell number J:160782
decreased marginal zone B cell number J:160782
decreased T cell number J:160782
decreased thymocyte number J:160782
decreased transitional stage T2 B cell number J:160782
Gimap3tm1.1Yout/Gimap3tm1.1Yout
(involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj)
decreased T cell number J:209926
decreased thymocyte number J:209926
Gimap4tm1Jcbs/Gimap4tm1Jcbs
(B6.129P2-Gimap4tm1Jcbs)
abnormal T cell physiology J:135744
Gimap5m1Btlr/Gimap5m1Btlr
(involves: C57BL/6J)
abnormal B cell physiology J:160090
abnormal B cell proliferation J:160090
abnormal NK T cell physiology J:160090
abnormal response to transplant J:160090
abnormal spleen B cell follicle morphology J:160090
colitis J:160090
decreased B cell number J:160090
decreased B cell proliferation J:160090
decreased B-1 B cell number J:160090
decreased CD8-positive, alpha-beta T cell number J:160090
decreased circulating interferon-gamma level J:160090
decreased circulating interleukin-4 level J:160090
decreased IgG1 level J:160090
decreased IgG2a level J:160090
decreased IgG2b level J:160090
decreased IgG3 level J:160090
decreased IgG level J:160090
decreased IgM level J:160090
decreased interferon-gamma secretion J:160090
decreased interleukin-4 secretion J:160090
decreased lymphocyte cell number J:160090
decreased mature B cell number J:160090
decreased NK cell number J:160090
decreased NK T cell number J:160090
decreased spleen B cell follicle number J:160090
decreased spleen B cell follicle size J:160090
decreased tumor necrosis factor secretion J:160090
increased granulocyte number J:160090
increased neutrophil cell number J:160090
intestinal inflammation J:160090
thymus atrophy J:160090
Gimap5m1Btlr/Gimap5m1Btlr
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C57BL/6J * DBA/2J)
decreased CD8-positive, alpha-beta T cell number J:160090
decreased thymocyte number J:160090
Gimap5tm1Wlr/Gimap5tm1Wlr
(either: B6.129-Gimap5tm1Wlr or C.129-Gimap5tm1Wlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:143620
abnormal leukocyte morphology J:143620
abnormal lymphocyte cell number J:143620
abnormal response to transplant J:143620
abnormal spleen morphology J:143620
decreased B cell number J:143620
decreased CD4-positive, alpha-beta T cell number J:143620
decreased CD8-positive, alpha-beta T cell number J:143620
decreased NK cell number J:143620
decreased NK T cell number J:143620
decreased T cell number J:143620
increased granulocyte number J:143620
small lymph nodes J:143620
spleen hypoplasia J:143620
Gimap5tm1Yout/Gimap5tm1Yout
(involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj)
decreased T cell number J:209926
Gimap6tm1.1Gwb/Gimap6tm1.1Gwb
Tg(CD2-icre)4Kio/0

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
abnormal leukocyte morphology J:262059
abnormal T cell physiology J:262059
decreased B cell number J:262059
decreased T cell number J:262059
increased B cell number J:262059
increased T cell apoptosis J:262059
Gimap6tm1a(KOMP)Wtsi/Gimap6tm1a(KOMP)Wtsi
(C57BL/6N-Gimap6tm1a(KOMP)Wtsi/Wtsi)
decreased CD4-negative NK T cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
increased memory-marker CD4-negative NK T cell number J:211773
increased monocyte cell number J:211773
Gin1em1(IMPC)Mbp/Gin1em1(IMPC)Mbp
(C57BL/6N-Gin1em1(IMPC)Mbp/MbpMmucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Git2Gt(XG510)Byg/Git2Gt(XG510)Byg
(B6.129P2-Git2Gt(XG510)Byg)
decreased marginal zone B cell number J:160613
Git2Gt(XG510)Byg/Git2Gt(XG510)Byg
(C.129P2-Git2Gt(XG510)Byg)
decreased marginal zone B cell number J:160613
Git2Gt(XG510)Byg/Git2Gt(XG510)Byg
Tg(DO11.10)10Dlo/0

(involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:160613
Git2Gt(XG510)Byg/Git2Gt(XG510)Byg
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129 * C57BL/6J * DBA/2J)
abnormal CD4-positive, alpha-beta T cell physiology J:160613
abnormal CD8-positive, alpha-beta T cell physiology J:160613
abnormal positive T cell selection J:160613
decreased CD8-positive, alpha-beta T cell number J:160613
Git2Gt(XG510)Byg/Git2Gt(XG510)Byg
Tg(TcraTcrb)425Cbn/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:160613
Git2tm1Hsb/Git2tm1Hsb
(involves: C57BL/6 * CBA)
abnormal neutrophil differentiation J:112663
abnormal neutrophil physiology J:112663
enlarged spleen J:112663
impaired neutrophil chemotaxis J:112663
increased susceptibility to fungal infection J:112663
lung inflammation J:112663
Gja1M1Jrt/Gja1+
(involves: C3H/HeJ * C57BL/6J)
heart inflammation J:101733
Gja1tm1.1Kwi/Gja1+
(involves: 129P2/OlaHsd)
abnormal neutrophil physiology J:129091
Gja1tm1Kwi/Gja1+
Tg(KRT5-cre)5132Jlj/0

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal lymphatic vessel morphology J:188626
absent lymphatic vessels J:188626
Gja1tm1Kwi/Gja1tm5(cre/ERT)Kwi
(involves: 129P2/OlaHsd)
abnormal neutrophil physiology J:129091
Gjb1tm1Kwi/Y
Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
microgliosis J:219594
optic nerve inflammation J:219594
spinal cord inflammation J:219594
Gjb2tm3.1(Gjb1)Kwi/Gjb2+
Tg(KRT5-cre)5132Jlj/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2J * SJL)
abnormal lymphatic vessel morphology J:188626
Gjb2tm3.2(Gjb1)Kwi/Gjb2+
(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL)
abnormal lymphatic vessel morphology J:188626
absent lymphatic vessels J:188626
Gjb4tm1.1(KOMP)Vlcg/Gjb4tm1.1(KOMP)Vlcg
(C57BL/6N-Gjb4tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Gjb6tm1Kwi/Gjb6tm1Kwi
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:85065
Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi
(involves: 129P2/OlaHsd * C57BL/6)
microgliosis J:174197
Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi
Gjb1tm1Kwi/Gjb1tm1Kwi

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
microgliosis J:219594
optic nerve inflammation J:219594
spinal cord inflammation J:219594
Gjc2tm2.1Kwi/Gjc2+
(involves: C57BL/6 * SJL)
microgliosis J:174197
Gjc2tm2.1Kwi/Gjc2tm2.1Kwi
(involves: C57BL/6 * SJL)
microgliosis J:174197
Gjd4tm1.1Malt/Gjd4tm1.1Malt
(involves: 129S2/SvPas * C57BL/6 * SJL)
decreased macrophage cell number J:172698
Gk5m5Btlr/Gk5m5Btlr
(C57BL/6J-Gk5m5Btlr)
increased alpha-beta T cell number J:265118
increased CD8-positive, alpha-beta memory T cell number J:265118
increased central memory CD8 positive, alpha-beta T cell number J:265118
Gkn2tm1.1(KOMP)Vlcg/Gkn2tm1.1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal chemokine level J:234656
abnormal cytokine level J:234656
abnormal innate immunity J:234656
abnormal interleukin level J:234656
abnormal susceptibility to bacterial infection J:234656
abnormal T-helper 1 physiology J:234656
abnormal tumor necrosis factor level J:234656
increased susceptibility to bacterial infection J:234656
stomach inflammation J:234656
Glb1tm1Jmat/Glb1tm1Jmat
(involves: C57BL/6 * CBA * ICR)
abnormal lymphopoiesis J:43534
abnormal macrophage chemotaxis J:102576
small spleen J:43534
Glb1l2tm1Lex/Glb1l2tm1Lex
(B6;129S5-Glb1l2tm1Lex/Mmucd)
decreased leukocyte cell number J:171883
decreased lymphocyte cell number J:171883
decreased NK cell number J:171883
Glg1Gt(RST092)Byg/Glg1+
(B6J.129P2-Glg1Gt(RST092)Byg)
abnormal cellular extravasation J:226586
abnormal leukocyte adhesion J:226586
enhanced leukocyte tethering or rolling J:226586
Glis2tm1Amj/Glis2tm1Amj
(involves: 129P2/OlaHsd * C57BL/6)
glomerulonephritis J:134208
GlmpGt(P084H04)Wrst/GlmpGt(P084H04)Wrst
(involves: 129S2/SvPas * C57BL/6)
abnormal Kupffer cell morphology J:208774
increased spleen weight J:208774
liver inflammation J:208774
Glmptm1Lex/Glmptm1Lex
(B6;129S5-Glmptm1Lex/Mmucd)
abnormal immune system physiology J:171883
liver inflammation J:171883
Glra1nmf11/Glra1nmf11
(C57BL/6J-Glra1nmf11/J)
small spleen J:78134
thymus atrophy J:78134
Glra2tm1b(KOMP)Wtsi/Y
(C57BL/6N-Glra2tm1b(KOMP)Wtsi/H)
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Glrbem1(IMPC)Tcp/Glrb+
(C57BL/6NCrl-Glrbem1(IMPC)Tcp/Tcp)
increased neutrophil cell number J:211773
increased spleen weight J:211773
Gls2em1(IMPC)Tcp/Gls2em1(IMPC)Tcp
(C57BL/6N-Gls2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Glt8d2tm1Lex/Glt8d2tm1Lex
(B6;129S5-Glt8d2tm1Lex/Mmucd)
abnormal adaptive immunity J:171883
decreased IgG1 level J:171883
decreased IgG2a level J:171883
Glyr1em1(IMPC)Tcp/Glyr1em1(IMPC)Tcp
(C57BL/6N-Glyr1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Gm572b2b1167Clo/Gm572b2b1167Clo
(C57BL/6J-Gm572b2b1167Clo)
spleen hypoplasia J:175213
Gm614tm1.1Cya/Gm614tm1.1Cya
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N)
decreased susceptibility to systemic lupus erythematosus J:307345
immune system phenotype J:307345
increased B cell apoptosis J:307345
Gm4922em1(IMPC)Tcp/Gm4922em1(IMPC)Tcp
(C57BL/6NCrl-Gm4922em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Gm5544tm1a(KOMP)Wtsi/Gm5544+
(C57BL/6N-Gm5544tm1a(KOMP)Wtsi/Wtsi)
decreased marginal zone B cell number J:211773
Gm5544tm1a(KOMP)Wtsi/Gm5544tm1a(KOMP)Wtsi
(C57BL/6N-Gm5544tm1a(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
Gm7694em1(IMPC)J/Gm7694em1(IMPC)J
(C57BL/6NJ-Gm7694em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Gm10800em1(IMPC)Mbp/Gm10800em1(IMPC)Mbp
(C57BL/6N-Gm10800em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Gm16685em1Osb/Gm16685em1Osb
(C57BL/6N-Gm16685em1Osb)
decreased susceptibility to colitis induced morbidity/mortality J:303079
Gm26330em1Liuq/Gm26330em1Liuq
(C57BL/6-Gm26330em1Liuq)
decreased NK cell number J:341056
Gm28729em1(IMPC)J/Gm28729em1(IMPC)J
(C57BL/6NJ-Gm28729em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Gm36723em1Flv/Gm36723em1Flv
(C57BL/6-Gm36723em1Flv)
abnormal lymphopoiesis J:258967
abnormal NK cell physiology J:258967
decreased interferon-gamma secretion J:258967
decreased lymphocyte cell number J:258967
decreased mature NK cell number J:258967
decreased NK cell number J:258967
decreased susceptibility to bacterial infection J:258967
immune system phenotype J:258967
impaired natural killer cell mediated cytotoxicity J:258967
increased immature NK cell number J:258967
Gm36723em2Flv/Gm36723em2Flv
(C57BL/6-Gm36723em2Flv)
immune system phenotype J:258967
Gm36723em3Flv/Gm36723em3Flv
(C57BL/6-Gm36723em3Flv)
decreased mature NK cell number J:258967
Gm40600em1Cya/Gm40600em1Cya
(C57BL/6-Gm40600em1Cya)
abnormal plasmablast number J:311878
decreased B cell number J:311878
decreased IgA level J:311878
decreased IgE level J:311878
decreased IgG1 level J:311878
decreased IgG2b level J:311878
decreased IgG2c level J:311878
decreased IgG3 level J:311878
decreased IgG level J:311878
decreased IgM level J:311878
decreased plasma cell number J:311878
immune system phenotype J:311878
increased B cell number J:311878
increased IgA level J:311878
increased IgE level J:311878
increased IgG1 level J:311878
increased IgG2b level J:311878
increased IgG2c level J:311878
increased IgG3 level J:311878
increased IgG level J:311878
increased IgM level J:311878
increased plasma cell number J:311878
Gm41610em1Scrp/Gm41610em1Scrp
(C57BL/6-Gm41610em1Scrp)
decreased susceptibility to endotoxin shock J:302605
immune system phenotype J:302605
increased circulating interleukin-5 level J:302605
increased circulating interleukin-13 level J:302605
Gmdstm1a(KOMP)Wtsi/Gmdstm1a(KOMP)Wtsi
(C57BL/6N-Gmdstm1a(KOMP)Wtsi/Wtsi)
decreased alpha-beta T cell number J:211773
decreased CD4-positive NK T cell number J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased CD8-positive, naive alpha-beta T cell number J:211773
decreased dendritic cell number J:211773
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased KLRG1+ CD8 alpha-beta T cell number J:211773
decreased KLRG1-positive NK cell number J:211773
decreased Ly6C-positive mature NK cell number J:211773
decreased macrophage cell number J:211773
decreased mature NK cell number J:211773
decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
decreased NK cell number J:211773
decreased plasmacytoid dendritic cell number J:211773
decreased regulatory T cell number J:211773
decreased T-helper cell number J:211773
decreased transitional stage T2 B cell number J:211773
increased CD4-negative NK T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
increased gamma-delta T cell number J:211773
increased granulocyte number J:211773
increased immature NK cell number J:211773
increased leukocyte cell number J:211773
increased Ly6C-positive NK T cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased memory-marker NK cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased NK T cell number J:211773
Gmnntm1.1Kio/Gmnntm1.2Kio
Tg(CD2-icre)4Kio/0

(involves: 129S4/SvJae * C57BL/10 * CBA/Ca)
decreased CD4-positive, alpha-beta T cell number J:159657
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:159657
decreased CD8-positive, alpha-beta T cell number J:159657
decreased DN1 thymic pro-T cell number J:159657
decreased DN4 thymocyte number J:159657
decreased double-positive T cell number J:159657
decreased memory T cell number J:159657
decreased T cell proliferation J:159657
decreased thymocyte number J:159657
Gmnntm1Tjm/Gmnntm1Tjm
Tg(Mx1-cre)1Cgn/0

(involves: 129/Sv * C57BL/6 * C57BL/6J * CBA)
abnormal spleen red pulp morphology J:171741
decreased granulocyte number J:171741
decreased leukocyte cell number J:171741
decreased neutrophil cell number J:171741
Gmppaem1(IMPC)Tcp/Gmppaem1(IMPC)Tcp
(C57BL/6N-Gmppaem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Gmpsem1(IMPC)Tcp/Gmps+
(C57BL/6NCrl-Gmpsem1(IMPC)Tcp/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Gna11tm1Soff/Gna11tm1Soff
(involves: 129S7/SvEvBrd)
decreased susceptibility to type I hypersensitivity reaction J:146132
Gna11tm1Soff/Gna11tm1Soff
Gnaqtm2Soff/Gnaqtm2Soff
Tg(Tek-icre/ERT2)1Soff/?

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N)
decreased susceptibility to type I hypersensitivity reaction J:146132
immune system phenotype J:146132
Gna12tm1.1Cgh/Gna12tm1.1Cgh
Gna13tm2Cgh/Gna13tm2Cgh
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
abnormal germinal center B cell morphology J:174313
decreased B cell apoptosis J:174313
increased germinal center B cell number J:174313
Gna12tm1Citb/Gna12tm1Citb
Gna13tm2.1Soff/Gna13tm2.1Soff
Tg(Lck-cre)548Jxm/0

(involves: 129S1/Sv * C57BL/6 * CBA)
abnormal CD4-positive, alpha-beta T cell physiology J:149560
increased CD4-positive, alpha-beta T cell number J:149560
increased CD8-positive, alpha-beta T cell number J:149560
increased interleukin-2 secretion J:149560
increased susceptibility to autoimmune diabetes J:149560
increased susceptibility to type IV hypersensitivity reaction J:149560
increased T cell proliferation J:149560
lymph node hyperplasia J:149560
thymus hyperplasia J:149560
Gna15em1(IMPC)Mbp/Gna15em1(IMPC)Mbp
(C57BL/6N-Gna15em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Gnai1tm1b(EUCOMM)Wtsi/Gnai1tm1b(EUCOMM)Wtsi
(C57BL/6N-Gnai1tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Gnai1tm1Drs/Gnai1tm1Drs
Gnai3tm1Lbi/Gnai3tm1Lbi

(involves: 129S/SvEv)
decreased interleukin-10 secretion J:104683
increased tumor necrosis factor secretion J:104683
Gnai2tm1Lbi/Gnai2tm1Lbi
(involves: 129S7/SvEvBrd * C57BL/6J)
colitis J:24434
Gnai2tm1Lbi/Gnai2tm1Lbi
(involves: 129S7/SvEvBrd)
abnormal cytokine level J:121471
abnormal cytokine secretion J:30507
abnormal immune system morphology J:30507
abnormal immune system physiology J:30507
abnormal neutrophil physiology J:121471
colitis J:24434
increased circulating interferon-gamma level J:121471
increased circulating interleukin-4 level J:121471
increased circulating interleukin-5 level J:121471
increased granulocyte number J:30507
increased IgA level J:30507
increased IgG level J:30507
increased immunoglobulin level J:30507
increased inflammatory response J:30507
increased interferon-gamma secretion J:30507
increased interleukin-2 secretion J:30507
increased single-positive T cell number J:30507
increased susceptibility to parasitic infection J:121471
increased T cell number J:30507
increased T cell proliferation J:30507
increased tumor necrosis factor secretion J:30507
large intestinal inflammation J:30507
peritoneal inflammation J:30507
Gnai2tm1Lbi/Gnai2tm1Lbi
(either: 129 or (involves: 129S7/SvEvBrd * C57BL/6J))
abnormal cytokine secretion J:24434
increased granulocyte number J:24434
increased IgG level J:24434
increased IgM level J:24434
increased thymocyte number J:24434
Gnai2tm1Lbi/Gnai2tm1Lbi
(129-Gnai2tm1Lbi)
abnormal cytokine secretion J:91100
immune system phenotype J:91100
increased interleukin-1 beta secretion J:91100
increased tumor necrosis factor secretion J:91100
Gnai2tm1Lbi/Gnai2tm1Lbi
(B6.129S7-Gnai2tm1Lbi)
abnormal cellular extravasation J:120069
abnormal eosinophil physiology J:120069
abnormal leukocyte adhesion J:120069
abnormal leukocyte cell number J:121161
abnormal T cell physiology J:121161
decreased eosinophil cell number J:120069
increased eosinophil cell number J:120069
increased lymphocyte cell number J:120069
increased monocyte cell number J:120069
increased neutrophil cell number J:120069
Gnai2tm1Lbi/Gnai2tm1Lbi
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal cytokine secretion J:91100
colitis J:91100
increased interleukin-1 beta secretion J:91100
increased tumor necrosis factor secretion J:91100
Gnai2tm2.1Lbi/Gnai2tm2.1Lbi
Tg(Cd4-cre)1Cwi/0

(involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * DBA)
decreased T-helper 17 cell number J:194587
increased susceptibility to induced colitis J:194587
Gnai3tm1Lbi/Gnai3tm1Lbi
(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:120069
Gnai3tm1Lbi/Gnai3tm1Lbi
(B6.129S-Gnai3tm1Lbi)
abnormal T cell physiology J:121161
Gnao1tm1b(EUCOMM)Hmgu/Gnao1+
(C57BL/6N-Gnao1tm1b(EUCOMM)Hmgu/H)
decreased eosinophil cell number J:211773
GnasOedsml/Gnas+
(involves: 101/H * C3H/HeH)
abnormal inflammatory response J:65007
Gnastm1Lsw/Gnas+
(involves: 129S4/SvJae * CD-1)
thymus cortex atrophy J:49340
Gnb1lGt(OST35527)Lex/Gnb1l+
(B6;129S5-Gnb1lGt(OST35527)Lex/Orl)
abnormal spleen B cell follicle morphology J:82809
glomerulonephritis J:82809
Gnb2em1(IMPC)J/Gnb2em1(IMPC)J
(C57BL/6NJ-Gnb2em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Gnb4em1(IMPC)H/Gnb4em1(IMPC)H
(C57BL/6NTac-Gnb4em1(IMPC)H/H)
enlarged spleen J:211773
Gnetm1.1Masn/Gnetm1.1Masn
(involves: 129P2/OlaHsd * C57BL/6)
kidney inflammation J:184315
Gngt2em1(IMPC)Bay/Gngt2em1(IMPC)Bay
(C57BL/6N-Gngt2em1(IMPC)Bay/BayMmucd)
increased spleen weight J:211773
Gnmttm1Ymac/Gnmttm1Ymac
(involves: 129 * C57BL/6)
decreased leukocyte cell number J:147857
decreased monocyte cell number J:147857
decreased neutrophil cell number J:147857
Gnpda1tm1b(KOMP)Mbp/Gnpda1+
(C57BL/6N-Gnpda1tm1b(KOMP)Mbp/Tcp)
increased neutrophil cell number J:211773
Gnptabem1(IMPC)Mbp/Gnptab+
(C57BL/6N-Gnptabem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Gnptabnym/Gnptabnym
(involves: BALB/cAnNHsd * C3H/HeNHsd)
brain inflammation J:218156
Gnptabtm1Dkji/Gnptabtm1Dkji
(involves: 129 * C57BL/6)
increased interleukin-6 secretion J:231531
Gnptabtm1Kkol/Gnptabtm1Kkol
(involves: 129 * C57BL/6)
abnormal osteoclast physiology J:202751
increased osteoclast cell number J:202751
Gnrh1hpg/Gnrh1hpg
(HPG/BmJ)
abnormal splenic cell ratio J:19436
increased B cell number J:19436
increased immature B cell number J:19436
increased mature B cell number J:19436
Gnstm1e(EUCOMM)Hmgu/Gnstm1e(EUCOMM)Hmgu
(C57BL/6N-Atm1Brd Gnstm1e(EUCOMM)Hmgu)
microgliosis J:242250
Golga2tm1(KOMP)Vlcg/Golga2tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
increased alveolar macrophage number J:270564
Golm1Gt(KST273)Byg/Golm1Gt(KST273)Byg
(involves: 129P2/OlaHsd * C57BL/6)
kidney inflammation J:151282
liver inflammation J:151282
Golph3em1(IMPC)Tcp/Golph3+
(C57BL/6NCrl-Golph3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Golph3em1(IMPC)Tcp/Golph3em1(IMPC)Tcp
(C57BL/6NCrl-Golph3em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
enlarged thymus J:211773
Golt1btm1b(EUCOMM)Wtsi/Golt1btm1b(EUCOMM)Wtsi
(C57BL/6N-Golt1btm1b(EUCOMM)Wtsi/Ieg)
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Gon4ljusty/Gon4ljusty
(C3HeB/FeJ-Gon4ljusty)
abnormal humoral immune response J:163412
absent B cells J:163412
arrested B cell differentiation J:163412
decreased B cell number J:163412
decreased immature B cell number J:163412
decreased immunoglobulin level J:163412
decreased pro-B cell number J:163412
decreased spleen white pulp amount J:163412
decreased T cell number J:163412
small spleen J:163412
spleen hypoplasia J:163412
Got1tm1b(EUCOMM)Hmgu/Got1+
(C57BL/6N-Got1tm1b(EUCOMM)Hmgu/H)
decreased basophil cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
Got2em1(IMPC)Mbp/Got2+
(C57BL/6N-Got2em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Gp2em1(IMPC)Mbp/Gp2em1(IMPC)Mbp
(C57BL/6N-Gp2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Gp6tm1Beni/Gp6tm1Beni
Clec1btm1.1Arte/Clec1btm1.1Arte
Tg(Pf4-icre)Q3Rsko/0

(involves: 129 * C57BL/6)
abnormal lymphatic vessel morphology J:217963
Gp6tm2b(EUCOMM)Hmgu/Gp6tm2b(EUCOMM)Hmgu
(C57BL/6N-Gp6tm2b(EUCOMM)Hmgu/Orl)
increased lymphocyte cell number J:211773
Gp9tm1.1(KOMP)Vlcg/Gp9tm1.1(KOMP)Vlcg
(C57BL/6N-Gp9tm1.1(KOMP)Vlcg/Ucd)
increased basophil cell number J:211773
Gpa33tm1Jkhh/Gpa33tm1Jkhh
(B6.129-Gpa33tm1Jkhh)
abnormal immune tolerance J:224768
increased dendritic cell number J:224768
increased susceptibility to induced colitis J:224768
increased susceptibility to type IV hypersensitivity reaction J:224768
Gpa33tm1Jkhh/Gpa33tm1Jkhh
(involves: 129 * C57BL/6)
increased susceptibility to colitis induced morbidity/mortality J:231808
increased susceptibility to induced colitis J:231808
Gpatch2em1Boui/Gpatch2em1Boui
(C57BL/6-Gpatch2em1Boui)
decreased B cell number J:336774
immune system phenotype J:336774
Gpatch3em1(IMPC)Mbp/Gpatch3em1(IMPC)Mbp
(C57BL/6N-Gpatch3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Gpbar1tm1.1(KOMP)Vlcg/Gpbar1tm1.1(KOMP)Vlcg
(C57BL/6N-Gpbar1tm1.1(KOMP)Vlcg/Ucd)
abnormal lymph node morphology J:211773
Gpc1em1(IMPC)Mbp/Gpc1em1(IMPC)Mbp
(C57BL/6N-Gpc1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Gpc3tm1Arge/Y
(either: (involves: 129S/SvEv * 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J))
decreased spleen weight J:75054
increased spleen B cell follicle size J:75054
small spleen J:75054
Gpc3tm1Fil/Y
(B6.Cg-Gpc3tm1Fil)
increased susceptibility to bacterial infection J:73877
lung inflammation J:73877
rhinitis J:73877
Gpc3tm1Fil/Gpc3tm1Fil
(B6.Cg-Gpc3tm1Fil)
increased susceptibility to bacterial infection J:73877
lung inflammation J:73877
Gpc3tm1Snd/Y
(involves: 129X1/SvJ * C57BL/6)
abnormal osteoclast differentiation J:104555
Gpcpd1em1(IMPC)Tcp/Gpcpd1+
(C57BL/6N-Gpcpd1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Gpdc1C3H/HeN/Gpdc1C3H/HeN
(involves: C3H/HeN-Gnai2tm1Uru * C57BL/6J-Gna2tm1Uru)
colitis J:95140
Gpdc2C3H/HeN/Gpdc2C3H/HeN
(involves: C3H/HeN-Gnai2tm1Uru * C57BL/6J-Gna2tm1Uru)
colitis J:95140
Gpdc3C3H/HeN/?
(involves: C3H/HeN-Gnai2tm1Uru * C57BL/6J-Gna2tm1Uru)
colitis J:95140
Gper1tm1Dgen/Gper1tm1Dgen
(B6.129-Gper1tm1Dgen)
decreased CD4-positive, alpha-beta T cell number J:151816
decreased CD8-positive, alpha-beta T cell number J:151816
decreased T cell number J:151816
Gpi1b-m1Neu/Gpi1b-m1Neu
(C3.Cg-Gpi1b-m1Neu)
increased spleen weight J:35956
Gpi1b-m2Neu/Gpi1b-m2Neu
(C3.Cg-Gpi1b-m2Neu)
increased spleen weight J:35956
Gpld1tm1.1(KOMP)Vlcg/Gpld1tm1.1(KOMP)Vlcg
(C57BL/6N-Gpld1tm1.1(KOMP)Vlcg/Ucd)
increased spleen weight J:211773
Gpm6btm1KanPlp1tm1Kan/Y
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
microgliosis J:193310
Gpnmbtm1Ari/Gpnmbtm1Ari
(C57BL/6-Gpnmbtm1Ari)
abnormal dendritic cell physiology J:215931
Gpr15tm1.1Litt/Gpr15tm1.1Litt
(B6.129P2-Gpr15tm1.1Litt)
abnormal regulatory T cell physiology J:199126
decreased CD4-positive, alpha-beta T cell number J:199126
decreased double-negative T cell number J:199126
decreased regulatory T cell number J:199126
immune system phenotype J:199126
increased CD8-positive, alpha-beta T cell number J:199126
increased susceptibility to bacterial infection J:199126
increased susceptibility to bacterial infection induced morbidity/mortality J:199126
increased susceptibility to induced colitis J:199126
Gpr15tm1.1Litt/Gpr15tm1.1Litt
(involves: 129P2/OlaHsd * C57BL/6)
decreased regulatory T cell number J:199126
increased interferon-gamma secretion J:199126
increased interleukin-17 secretion J:199126
Gpr15tm1.1Litt/Gpr15tm1.1Litt
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraTcrb)425Cbn/0

(involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6)
abnormal immune system physiology J:199126
Gpr15lgtm1Lex/Gpr15lgtm1Lex
(B6;129S5-Gpr15lgtm1Lex/Mmucd)
increased IgG2a level J:171883
Gpr17tm1b(KOMP)Mbp/Gpr17tm1b(KOMP)Mbp
(C57BL/6N-Gpr17tm1b(KOMP)Mbp/Tcp)
increased neutrophil cell number J:211773
Gpr18tm1.1Cys/Gpr18tm1.1Cys
(involves: C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:219661
decreased CD8-positive, gamma-delta intraepithelial T cell number J:219661
immune system phenotype J:219661
Gpr18tm1Lex/Gpr18tm1Lex
(involves: 129S/SvEv * C57BL/6)
increased susceptibility to bacterial infection J:226433
Gpr21tm1Dgen/Gpr21tm1Dgen
(B6.129P2-Gpr21tm1Dgen)
abnormal circulating chemokine level J:181127
decreased circulating serum amyloid protein level J:181127
Gpr31btm1Ktak/Gpr31btm1Ktak
(B6.Cg-Gpr31btm1Ktak)
abnormal dendritic cell physiology J:271242
decreased inflammatory response J:271242
increased susceptibility to bacterial infection J:271242
Gpr34tm1.1Shbg/Gpr34tm1.1Shbg
(B6.Cg-Gpr34tm1.1Shbg)
abnormal chemokine secretion J:168120
abnormal cytokine secretion J:168120
abnormal leukocyte migration J:168120
increased interferon-gamma secretion J:168120
increased interleukin-2 secretion J:168120
increased interleukin-4 secretion J:168120
increased interleukin-5 secretion J:168120
increased interleukin-10 secretion J:168120
increased interleukin-12 secretion J:168120
increased susceptibility to fungal infection J:168120
increased susceptibility to type IV hypersensitivity reaction J:168120
increased tumor necrosis factor secretion J:168120
Gpr35em1Niess/Gpr35em1Niess
(C57BL/6N-Gpr35em1Niess)
immune system phenotype J:300275
increased susceptibility to induced colitis J:300275
Gpr35em2Niess/Gpr35em2Niess
Cx3cr1tm2.1(cre/ERT2)Litt/Cx3cr1+

(involves: 129P2/OlaHsd * C57BL/6N)
increased susceptibility to induced colitis J:300275
Gpr35tm1(KOMP)Vlcg/Gpr35tm1(KOMP)Vlcg
(C57BL/6N-Gpr35tm1(KOMP)Vlcg/MbpMmucd)
abnormal chemokine level J:306520
abnormal interleukin level J:306520
decreased susceptibility to colitis induced morbidity/mortality J:306520
decreased susceptibility to induced colitis J:306520
Gpr55tm1.1Mijr/Gpr55tm1.1Mijr
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal osteoclast differentiation J:153225
abnormal osteoclast morphology J:153225
abnormal osteoclast physiology J:153225
decreased osteoclast cell number J:153225
increased osteoclast cell number J:153225
Gpr65tm1Witt/Gpr65tm1Witt
(B6.Cg-Gpr65tm1Witt)
abnormal immune cell physiology J:96112
abnormal leukocyte physiology J:96112
Gpr65tm1Witt/Gpr65tm1Witt
(C.Cg-Gpr65tm1Witt)
abnormal leukocyte physiology J:96112
Gpr65Tn(sb-lacZ,GFP)T1.88Jtak/Gpr65Tn(sb-lacZ,GFP)T1.88Jtak
(B6.Cg-Gpr65Tn(sb-lacZ,GFP)T1.88Jtak)
abnormal interleukin-1 beta secretion J:208788
abnormal macrophage physiology J:146233
decreased tumor necrosis factor secretion J:146233
Gpr68tm1.1Yaxu/Gpr68tm1.1Yaxu
(B6.Cg-Gpr68tm1.1Yaxu)
abnormal osteoclast differentiation J:149315
abnormal osteoclast physiology J:149315
immune system phenotype J:149315
Gpr68tm1.1Yaxu/Gpr68tm1.1Yaxu
(involves: 129S4/SvJae * C57BL/6 * FVB/N)
abnormal macrophage physiology J:149315
abnormal osteoclast differentiation J:149315
abnormal osteoclast physiology J:149315
decreased macrophage cell number J:149315
increased monocyte cell number J:149315
Gpr68tm1Aha/Gpr68tm1Aha
(B6.129-Gpr68tm1Aha)
immune system phenotype J:146233
Gpr68tm1Yaxu/Gpr68tm1Yaxu
(involves: C57BL/6)
abnormal macrophage physiology J:149315
abnormal osteoclast differentiation J:149315
abnormal osteoclast physiology J:149315
decreased monocyte cell number J:149315
Gpr83em1(IMPC)Ccpcz/Gpr83em1(IMPC)Ccpcz
(C57BL/6NCrl-Gpr83em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased CD4-positive NK T cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
decreased NK T cell number J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Gpr83tm1.1Fpow/Gpr83tm1.1Fpow
(C.129-Gpr83tm1.1Fpow)
decreased CD4-positive, alpha-beta T cell number J:144445
immune system phenotype J:144445
spleen hyperplasia J:144445
Gpr84tm1Lex/Gpr84tm1Lex
(involves: 129S/SvEvBrd * C57BL/6)
abnormal T-helper 2 physiology J:186985
immune system phenotype J:186985
increased interleukin-4 secretion J:186985
increased interleukin-5 secretion J:186985
increased interleukin-13 secretion J:186985
Gpr89ex/Gpr89ex
(C57BL/6J-Gpr89ex)
abnormal T cell morphology J:287198
abnormal T cell number J:287198
Gpr89tm1.1Ymae/Gpr89tm1.1Ymae
Tg(KRT5-cre)1Tak/0

(involves: C3H * C57BL/6)
dermatitis J:189574
Gpr108tm1.1Brs/Gpr108tm1.1Brs
(involves: 129S6/SvEvTac)
decreased susceptibility to bacterial infection induced morbidity/mortality J:266821
decreased tumor necrosis factor secretion J:266821
increased interleukin-6 secretion J:266821
increased susceptibility to endotoxin shock J:266821
increased tumor necrosis factor secretion J:266821
Gpr132tm1Witt/Gpr132tm1Witt
(B6.129X1-Gpr132tm1Witt)
impaired macrophage chemotaxis J:96613
Gpr132tm1Witt/Gpr132tm1Witt
(involves: 129X1/SvJ * BALB/c)
abnormal immune system organ morphology J:69473
abnormal lymph node morphology J:69473
abnormal lymphocyte physiology J:69473
enlarged inguinal lymph nodes J:69473
enlarged spleen J:69473
increased anti-nuclear antigen antibody level J:69473
increased B cell proliferation J:69473
increased IgA level J:69473
increased IgG1 level J:69473
increased immunoglobulin level J:69473
increased inflammatory response J:69473
increased T cell proliferation J:69473
kidney inflammation J:69473
liver inflammation J:69473
lung inflammation J:69473
Gpr132tm1Witt/Gpr132tm1Witt
Ldlrtm1Her/Ldlrtm1Her

(B6.129-Ldlrtm1Her Gpr132tm1Witt)
decreased macrophage apoptosis J:100498
Gpr146em1(IMPC)H/Gpr146em1(IMPC)H
(C57BL/6NTac-Gpr146em1(IMPC)H/H)
increased spleen weight J:211773
Gpr146em1Bdu/Gpr146em1Bdu
(C57BL/6-Gpr146em1Bdu)
immune system phenotype J:247263
Gpr155em1(IMPC)Mbp/Gpr155em1(IMPC)Mbp
(C57BL/6N-Gpr155em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Gpr174tm1Cys/Y
(B6.129-Gpr174tm1Cys)
abnormal regulatory T cell physiology J:222307
abnormal T-helper 1 cell differentiation J:222307
decreased susceptibility to experimental autoimmune encephalomyelitis J:222307
immune system phenotype J:222307
increased single-positive T cell number J:222307
increased T cell proliferation J:222307
Gpr174tm1Cys/Gpr174+
(B6.129-Gpr174tm1Cys)
decreased susceptibility to experimental autoimmune encephalomyelitis J:222307
Gpr182tm2b(KOMP)Wtsi/Gpr182tm2b(KOMP)Wtsi
(C57BL/6N-Gpr182tm2b(KOMP)Wtsi/Ucd)
increased spleen weight J:211773
Gpr182tm2c(KOMP)Wtsi/Gpr182tm2c(KOMP)Wtsi
Tg(Cdh5-cre/ERT2)1Rha/0

(B6.Cg-Gpr182tm2c(KOMP)Wtsi Tg(Cdh5-cre/ERT2)1Rha)
abnormal circulating chemokine level J:305796
increased circulating CXCL10 level J:305796
increased monocyte cell number J:305796
increased neutrophil cell number J:305796
Gpr183tm1.1Cys/Gpr183tm1.1Cys
(B6.129P2-Gpr183tm1.1Cys)
abnormal follicular B cell physiology J:151077
Gpr183tm1.2Rbr/Gpr183tm1.2Rbr
(involves: C57BL/6 * FVB/N * SJL)
abnormal B cell physiology J:151883
decreased plasma cell number J:151883
Gpr183tm1.2Rbr/Gpr183tm1.2Rbr
Ightm1Rbr/Ightm1Rbr
Tg(IgkHyHEL10)1Rbr/0

(involves: C57BL/6 * FVB/N * SJL)
abnormal B cell physiology J:151883
abnormal B cell proliferation J:151883
decreased B cell number J:151883
decreased IgG1 level J:151883
decreased IgM level J:151883
decreased plasma cell number J:151883
Gpr183tm1Lex/Gpr183tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal circulating interferon-beta level J:211122
decreased myeloid dendritic cell number J:211122
decreased plasmacytoid dendritic cell number J:211122
increased circulating interferon-alpha level J:211122
increased circulating interferon-gamma level J:211122
Gprc5atm1Rlo/Gprc5atm1Rlo
(involves: 129 * C57BL/6)
lung inflammation J:127821
Gprc5ctm1Yhir/Gprc5ctm1Yhir
(B6.Cg-Gprc5ctm1Yhir)
increased basophil cell number J:176063
Gprc6atm1.1(KOMP)Vlcg/Gprc6atm1.1(KOMP)Vlcg
(C57BL/6N-Gprc6atm1.1(KOMP)Vlcg/Ucd)
increased thymus weight J:211773
Gprin1em1(IMPC)H/Gprin1em1(IMPC)H
(C57BL/6N-Gprin1em1(IMPC)H/H)
decreased neutrophil cell number J:211773
Gpsm3Gt(IST12408A1)Tigm/Gpsm3Gt(IST12408A1)Tigm
(involves: C57BL/6N)
abnormal leukocyte migration J:193270
abnormal leukocyte physiology J:193270
decreased monocyte cell number J:193270
decreased susceptibility to induced arthritis J:193270
Gpx1tm1Kola/Gpx1tm1Kola
(involves: 129S2/SvPas * BALB/c * CF-1)
increased inflammatory response J:79183
Gpx1tm1Kola/Gpx1tm1Kola
(B6.129S2(CF1)-Gpx1tm1Kola)
immune system phenotype J:100436
Gpx1tm1Ysh/Gpx1+
Gpx2tm2Coh/Gpx2tm2Coh

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
intestinal inflammation J:71506
Gpx1tm1Ysh/Gpx1tm1Ysh
Gpx2tm2Coh/Gpx2+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
intestinal inflammation J:71506
Gpx1tm1Ysh/Gpx1tm1Ysh
Gpx2tm2Coh/Gpx2tm2Coh

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
colitis J:71506
intestinal inflammation J:71506
small intestinal inflammation J:71506
Gpx7tm1Whle/Gpx7tm1Whle
(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:193993
enlarged spleen J:193993
glomerulonephritis J:193993
increased anti-nuclear antigen antibody level J:193993
Gpx8tm1Lex/Gpx8tm1Lex
(B6;129S5-Gpx8tm1Lex/Mmucd)
dermatitis J:171883
Gramd2aem1(IMPC)Tcp/Gramd2aem1(IMPC)Tcp
(C57BL/6NCrl-Gramd2aem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Grap2tm1Amch/Grap2tm1Amch
(involves: 129S1/Sv * 129X1/SvJ)
arrested T cell differentiation J:76696
decreased CD4-positive, alpha-beta T cell number J:76696
decreased CD8-positive, alpha-beta T cell number J:76696
decreased thymocyte number J:76696
increased double-negative T cell number J:76696
Grap2tm1Amch/Grap2tm1Amch
Lcp2tm1.1Wz/Lcp2tm1.1Wz

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal T cell differentiation J:150304
decreased CD4-positive, alpha-beta T cell number J:150304
decreased CD8-positive, alpha-beta T cell number J:150304
decreased double-positive T cell number J:150304
decreased single-positive T cell number J:150304
Grap2tm1Eac/Grap2tm1Eac
(involves: C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:92023
abnormal double-negative T cell morphology J:92023
decreased T cell number J:92023
decreased thymocyte number J:92023
increased activated T cell number J:92023
increased memory T cell number J:92023
Graptm1Gsf/Graptm1Gsf
(B6.129-Graptm1Gsf)
increased CD4-positive, alpha-beta T cell number J:76243
increased T cell proliferation J:76243
Grass1C57BL/6J/Grass1C57BL/6J
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to bacterial infection J:134374
decreased susceptibility to bacterial infection induced morbidity/mortality J:134374
sepsis J:134374
Grass1C57BL/6J/Grass1DBA/2J
(involves: C57BL/6J * DBA/2J)
increased susceptibility to bacterial infection J:134374
sepsis J:134374
Grass1DBA/2J/Grass1DBA/2J
(involves: C57BL/6J * DBA/2J)
increased susceptibility to bacterial infection J:134374
sepsis J:134374
Grb2tm1.1Hua/Grb2tm1.1Hua
Tg(DO11.10)10Dlo/0
Tg(Lck-cre)1Jtak/0

(involves: 129 * BALB/c * C3H * C57BL/6)
abnormal T cell differentiation J:161294
decreased CD4-positive, alpha-beta T cell number J:161294
Grb2tm1.1Hua/Grb2tm1.1Hua
Tg(Lck-cre)1Jtak/0

(involves: 129 * C57BL/6)
abnormal T cell differentiation J:161294
decreased CD4-positive, alpha-beta T cell number J:161294
decreased CD8-positive, alpha-beta T cell number J:161294
decreased double-positive T cell number J:161294
decreased thymocyte number J:161294
Grb2tm1.1Hua/Grb2tm1.1Hua
Tg(Lck-cre)1Jtak/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129 * C57BL/6 * C57BL/6J * DBA/2J)
abnormal T cell differentiation J:161294
decreased CD4-positive, alpha-beta T cell number J:161294
decreased CD8-positive, alpha-beta T cell number J:161294
increased CD8-positive, alpha-beta T cell number J:161294
increased double-positive T cell number J:161294
Grb2tm1Lnit/Grb2tm1Lnit
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * BALB/cJ)
abnormal B cell differentiation J:171222
abnormal B cell physiology J:171222
abnormal memory B cell physiology J:171222
decreased B cell number J:171222
decreased follicular B cell number J:171222
decreased IgG3 level J:171222
decreased IgG level J:171222
decreased mature B cell number J:171222
decreased spleen germinal center number J:171222
decreased spleen germinal center size J:171222
decreased transitional stage T1 B cell number J:171222
decreased transitional stage T2 B cell number J:171222
increased B cell apoptosis J:171222
increased B cell proliferation J:171222
increased IgM level J:171222
increased plasma cell number J:171222
Grb2tm1Paw/Grb2+
(involves: 129S1/Sv * 129X1/SvJ * BALB/c)
decreased susceptibility to Retroviridae infection J:122429
Grb14tm1Daly/Grb14tm1Daly
(involves: 129X1/SvJ * C57BL/6)
decreased spleen weight J:87892
Greb1em1Rkom/Greb1em1Rkom
(C57BL/6NJ-Greb1em1Rkom)
abnormal response to transplant J:346713
Grem2em1Stpg/Grem2em1Stpg
(involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J)
ovary inflammation J:318711
Grem2tm1Akh/Grem2tm1Akh
(involves: 129/Sv * C57BL/6)
abnormal chemokine level J:250034
increased inflammatory response J:250034
increased interleukin-10 secretion J:250034
increased leukocyte cell number J:250034
Grem2tm1Lex/Grem2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
immune system phenotype J:227246
Grhl3tm1a(EUCOMM)Wtsi/Grhl3+
(C57BL/6N-Grhl3tm1a(EUCOMM)Wtsi/Ics)
decreased IgE level J:165965
GrhprGt(OST383093)Lex/GrhprGt(OST383093)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
urinary bladder inflammation J:181969
Grik3em1(IMPC)Mbp/Grik3em1(IMPC)Mbp
(C57BL/6N-Grik3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
Grik5em1(IMPC)Mbp/Grik5em1(IMPC)Mbp
(C57BL/6N-Grik5em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Grk2tm1Gwd/Grk2tm1Gwd
Cd79atm1(cre)Reth/Cd79a+

(involves: 129 * BALB/c * C57BL/6)
abnormal B cell physiology J:176118
decreased B cell number J:176118
increased B cell number J:176118
increased CD4-positive, alpha-beta T cell number J:176118
increased CD8-positive, alpha-beta T cell number J:176118
increased follicular B cell number J:176118
increased marginal zone B cell number J:176118
Grk2tm1Gwd/Grk2tm1Mca
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
abnormal T cell physiology J:176118
decreased CD4-positive, alpha-beta T cell number J:176118
decreased CD8-positive, alpha-beta T cell number J:176118
decreased T cell number J:176118
impaired leukocyte tethering or rolling J:176118
increased B cell number J:176118
Grk6tm1.1Mca/Grk6tm1.1Mca
(involves: 129S4/SvJae * C57BL/6J)
abnormal B cell physiology J:76872
abnormal T cell physiology J:76872
Grk6tm1.1Mca/Grk6tm1.1Mca
(B6.129S4-Grk6tm1.1Mca)
abnormal T cell subpopulation ratio J:225063
decreased CD8-positive, alpha-beta T cell number J:225063
decreased CD8-positive, naive alpha-beta T cell number J:225063
enlarged spleen J:225063
glomerulonephritis J:225063
impaired macrophage phagocytosis J:225063
increased anti-double stranded DNA antibody level J:225063
increased IgG level J:225063
increased memory T cell number J:225063
increased spleen iron level J:225063
increased spleen weight J:225063
increased spleen white pulp amount J:225063
increased splenocyte number J:225063
Grntm1.1Aidi/Grntm1.1Aidi
(involves: C57BL/6 * C57BL/6J)
abnormal chemokine secretion J:156824
abnormal macrophage physiology J:156824
abnormal microglial cell physiology J:156824
increased interleukin-6 secretion J:156824
increased interleukin-12 secretion J:156824
increased susceptibility to bacterial infection J:156824
increased tumor necrosis factor secretion J:156824
microgliosis J:156824
Grntm1.1Aidi/Grntm1.1Aidi
(involves: C57BL/6J)
kidney inflammation J:268827
Grntm1.1Far/Grntm1.1Far
(involves: 129S4/SvJae * FVB/N)
abnormal macrophage physiology J:170823
Grntm1.1Far/Grntm1.1Far
(involves: 129S4/SvJae * C57BL/6J * FVB/N)
increased interleukin-1 beta secretion J:188324
increased interleukin-6 secretion J:188324
increased interleukin-10 secretion J:188324
increased tumor necrosis factor secretion J:188324
microgliosis J:188324
Grntm1.1Geno/Grntm1.1Geno
(involves: 129 * C57BL/6J)
microgliosis J:188420
Grntm1Blrl/Grntm1Blrl
(involves: C57BL/6J)
microgliosis J:182051
Grntm1Far/Grntm1Far
Tg(ITGAM-cre)2781Gkl/0

(involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N)
microgliosis J:188324
Grntm2.1Far/Grntm2.1Far
(involves: 129S4/SvJae * C57BL/6)
abnormal macrophage physiology J:259651
microgliosis J:259651
Grsf1tm1b(EUCOMM)Wtsi/Grsf1tm1b(EUCOMM)Wtsi
(C57BL/6N-Grsf1tm1b(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Gsdma3Ae/Gsdma3+
(involves: C57BL/6J * CAST/Ei)
enlarged lymph nodes J:180149
enlarged spleen J:180149
enlarged thymus J:180149
skin inflammation J:180149
Gsdma3M2Btlr/Gsdma3M2Btlr
(involves: C57BL/6J)
dermatitis J:209203
Gsdma3tm1(KOMP)Vlcg/Gsdma3tm1(KOMP)Vlcg
(C57BL/6N-Gsdma3tm1(KOMP)Vlcg/Nju)
increased lymphocyte cell number J:211773
Gsdmaem1Cya/Gsdmaem1Cya
(C57BL/6J-Gsdmaem1Cya)
increased susceptibility to bacterial infection J:326434
increased susceptibility to bacterial infection induced morbidity/mortality J:326434
Gsdmcem1(IMPC)Tcp/Gsdmcem1(IMPC)Tcp
(C57BL/6NCrl-Gsdmcem1(IMPC)Tcp/TcpMmucd)
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
Gsdmdem1Fcw/Gsdmdem2Fcw
(involves: C57BL/6)
abnormal macrophage apoptosis J:226781
decreased interleukin-1 beta secretion J:226781
Gsdmdem1Flv/Gsdmdem1Flv
(C57BL/6N-Gsdmdem1Flv)
increased susceptibility to Riboviria infection induced morbidity/mortality J:243487
Gsdmdem3Fcw/Gsdmdem3Fcw
(involves: C57BL/6)
abnormal macrophage apoptosis J:226781
decreased interleukin-1 beta secretion J:226781
Gsdmdem4Fcw/Gsdmdem4Fcw
(C57BL/6N-Gsdmdem4Fcw/J)
abnormal macrophage apoptosis J:101977
abnormal susceptibility to bacterial infection J:101977
Gsdmdm1Btlr/Gsdmdm1Btlr
(C57BL/6J-Gsdmdm1Btlr)
decreased interleukin-1 beta secretion J:267555
Gsg1lem1(IMPC)Mbp/Gsg1lem1(IMPC)Mbp
(C57BL/6N-Gsg1lem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Gsk3atm1Dral/Gsk3atm1Dral
Gsk3btm1Dral/Gsk3btm1Dral

(involves: 129P2/OlaHsd)
increased circulating interleukin-6 level J:200517
Gsntm1Djk/Gsntm1Djk
(either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6))
abnormal immune system physiology J:24346
abnormal osteoclast differentiation J:60625
abnormal osteoclast physiology J:60625
decreased inflammatory response J:24346
impaired neutrophil chemotaxis J:24346
impaired neutrophil recruitment J:24346
increased leukocyte cell number J:24346
increased neutrophil cell number J:24346
Gsrem1(IMPC)Mbp/Gsrem1(IMPC)Mbp
(C57BL/6N-Gsrem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Gsta4tm1Pzim/Gsta4+
(involves: 129S1/Sv * 129S6/SvEvTac)
increased susceptibility to bacterial infection J:87983
Gsta4tm1Pzim/Gsta4tm1Pzim
(involves: 129S1/Sv * 129S6/SvEvTac)
abnormal bone marrow development J:87983
increased susceptibility to bacterial infection J:87983
Gstcdtm1b(EUCOMM)Wtsi/Gstcdtm1b(EUCOMM)Wtsi
(C57BL/6N-Gstcdtm1b(EUCOMM)Wtsi/Bay)
enlarged spleen J:211773
Gstcdtm1b(EUCOMM)Wtsi/Gstcdtm1b(EUCOMM)Wtsi
(C57BL/6-Gstcdtm1b(EUCOMM)Wtsi)
increased tumor necrosis factor secretion J:279480
Gstk1tm1Pgb/Gstk1tm1Pgb
(BALB/c-Gstk1tm1Pgb)
decreased spleen red pulp amount J:177201
decreased spleen weight J:177201
glomerulonephritis J:177201
urethritis J:177201
urinary bladder inflammation J:177201
Gstm4tm2b(EUCOMM)Hmgu/Gstm4tm2b(EUCOMM)Hmgu
(C57BL/6N-Gstm4tm2b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
Gstz1tm1Pgb/Gstz1tm1Pgb
(BALB/c-Gstz1tm1Pgb/AnuApb)
chronic inflammation J:91519
decreased leukocyte cell number J:91519
decreased spleen weight J:91519
liver inflammation J:91519
Gsx1tm1Ssp/Gsx1tm1Ssp
(involves: 129P2/OlaHsd)
decreased leukocyte cell number J:31764
decreased lymphocyte cell number J:31764
decreased neutrophil cell number J:31764
Gt(ROSA)26Sorem1(DPP4)Yowa/Gt(ROSA)26Sorem1(DPP4)Yowa
(C57BL/6-Gt(ROSA)26Sorem1(DPP4)Yowa)
increased susceptibility to Coronaviridae infection J:279060
Gt(ROSA)26Sorem1(Ube2s)Chaw/?
(involves: C57BL/6)
decreased interferon level J:306461
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:306461
Gt(ROSA)26Sortm1(B4galt1)Clib/Gt(ROSA)26Sortm1(B4galt1)Clib
Tg(Nes-cre)Wme/?

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
decreased acute inflammation J:209737
decreased circulating interleukin-6 level J:209737
decreased susceptibility to induced colitis J:209737
Gt(ROSA)26Sortm1(CAG-Bcl3,-EGFP)Hoev/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:208980
abnormal B-2 B cell morphology J:208980
abnormal class switch recombination J:208980
abnormal follicular B cell morphology J:208980
abnormal Peyer's patch germinal center morphology J:208980
abnormal transitional stage T3 B cell morphology J:208980
absent marginal zone B cells J:208980
decreased B cell apoptosis J:208980
decreased B cell proliferation J:208980
decreased B-1 B cell number J:208980
decreased B-1a cell number J:208980
decreased IgG1 level J:208980
decreased IgG2b level J:208980
decreased IgG3 level J:208980
decreased IgM level J:208980
decreased immature B cell number J:208980
decreased marginal zone B cell number J:208980
decreased transitional stage T1 B cell number J:208980
enlarged spleen J:208980
increased lymphocyte cell number J:208980
Gt(ROSA)26Sortm1(CAG-CAMK2G*T287D,-EGFP)Whua/Gt(ROSA)26Sor+
Tg(Vil1-cre)997Gum/0

(involves: 129 * C57BL/6)
decreased susceptibility to induced colitis J:243363
Gt(ROSA)26Sortm1(CAG-Foxn1/ERT2,-GFP)Cbln/Gt(ROSA)26Sor+
Foxn1tm3(cre)Nrm/Foxn1+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal thymus involution J:208852
increased T cell number J:208852
Gt(ROSA)26Sortm1(CAG-FOXO1,GFP)Moli/Gt(ROSA)26Sor+
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:189962
Gt(ROSA)26Sortm1(CAG-NPM1*)Geno/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
enlarged spleen J:196690
myeloid hyperplasia J:196690
Gt(ROSA)26Sortm1(CAG-NPM1*)Geno/Gt(ROSA)26Sortm1(CAG-NPM1*)Geno
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
enlarged spleen J:196690
Gt(ROSA)26Sortm1(CAG-Slc39a14*L438R)Wvh/Gt(ROSA)26Sor+
Tg(Runx2-icre)1Jtuc/0

(involves: FVB/N)
increased osteoclast cell number J:261326
Gt(ROSA)26Sortm1(CARD14*)Ribt/Gt(ROSA)26Sor+
Malt1tm1c(EUCOMM)Hmgu/Malt1tm1c(EUCOMM)Hmgu
Tg(KRT14-cre/ERT)20Efu/0

(involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1)
increased dendritic cell number J:292094
increased neutrophil cell number J:292094
skin inflammation J:292094
Gt(ROSA)26Sortm1(CARD14*)Ribt/Gt(ROSA)26Sor+
Tg(KRT14-cre/ERT)20Efu/0

(involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1)
increased dendritic cell number J:292094
increased neutrophil cell number J:292094
skin inflammation J:292094
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Mcl1tm1Ywh/Mcl1tm1Ywh

(involves: 129/Sv * 129S6/SvEvTac * C57BL/6)
increased T cell apoptosis J:137400
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sortm1(Tcfe2a/Tal1)Xhsu
(involves: 129/Sv * C57BL/6)
abnormal lymphopoiesis J:144569
abnormal myelopoiesis J:144569
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sortm1(Pyy)Paba
(involves: 129S4/SvJae)
abnormal osteoclast morphology J:189512
increased osteoclast cell number J:189512
Gt(ROSA)26Sortm1(CTNNB1)Nerl/Gt(ROSA)26Sortm1(CTNNB1)Nerl
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA)
arrested T cell differentiation J:112660
decreased double-negative T cell number J:112660
decreased granulocyte number J:112660
decreased leukocyte cell number J:112660
impaired myelopoiesis J:112660
thymus hypoplasia J:112660
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Tg(Plp1-cre/ERT)3Pop/0

(involves: 129S/SvEv * C57BL/6 * DBA/2)
autoimmune response J:234435
CNS inflammation J:234435
increased activated T cell number J:234435
lymph node inflammation J:234435
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Tg(Trpv1-cre)1Hoon/0

(involves: 129S1/Sv)
decreased inflammatory response J:169256
Gt(ROSA)26Sortm1(DTA)Lky/?
Il5tm1.1(icre)Lky/Il5+
Rag1tm1Mom/Rag1tm1Mom

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
abnormal immune system physiology J:206097
Gt(ROSA)26Sortm1(DTA)Lky/Gt(ROSA)26Sor+
Il13tm1(YFP/cre)Lky/Il13tm1(YFP/cre)Lky

(involves: 129P2/OlaHsd * 129S4/SvJae)
decreased eosinophil cell number J:178986
decreased IgG1 level J:178986
decreased interleukin-5 secretion J:178986
decreased interleukin-13 secretion J:178986
increased susceptibility to parasitic infection J:178986
Gt(ROSA)26Sortm1(DTA)Lky/Gt(ROSA)26Sortm1(DTA)Lky
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:133382
abnormal CD8-positive, alpha-beta T cell differentiation J:133382
abnormal lymph node T cell domain morphology J:133382
abnormal spleen morphology J:133382
abnormal T cell receptor V(D)J recombination J:133382
decreased CD4-positive, alpha-beta T cell number J:133382
decreased CD8-positive, alpha-beta T cell number J:133382
decreased double-positive T cell number J:133382
decreased lymphocyte cell number J:133382
decreased NK T cell number J:133382
decreased regulatory T cell number J:133382
immune system phenotype J:133382
increased susceptibility to parasitic infection J:133382
Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sortm1(DTA)Riet
Tg(Rorc-cre)1Litt/?

(involves: 129P2/OlaHsd)
abnormal effector T cell morphology J:137020
Gt(ROSA)26Sortm1(DUX4)Sqh/Gt(ROSA)26Sor+
Tg(ACTA1-cre/Esr1*)2Kesr/0

(involves: 129S6/SvEvTac * C3H * C57BL/6)
abnormal acute inflammation J:268959
Gt(ROSA)26Sortm1(ETV6/SYK)Hjum/Gt(ROSA)26Sor+
Cd79atm3(cre/ERT2)Reth/Cd79a+

(involves: 129S6/SvEvTac * BALB/c)
abnormal circulating chemokine level J:208904
abnormal cytokine level J:208904
abnormal plasma cell differentiation J:208904
enlarged lymph nodes J:208904
enlarged spleen J:208904
increased B cell apoptosis J:208904
increased B cell number J:208904
increased B cell proliferation J:208904
increased circulating interferon-gamma level J:208904
increased circulating interleukin-6 level J:208904
increased circulating interleukin-10 level J:208904
increased circulating tumor necrosis factor level J:208904
increased IgM level J:208904
increased interferon-gamma secretion J:208904
increased interleukin-10 secretion J:208904
increased tumor necrosis factor secretion J:208904
Gt(ROSA)26Sortm1(ETV6/SYK)Hjum/Gt(ROSA)26Sor+
Cd79atm3(cre/ERT2)Reth/Cd79a+
Tg(BCL2)22Wehi/0

(involves: 129S6/SvEvTac * BALB/c * C57BL/6JWehi * SJL/JWehi)
abnormal B cell physiology J:208904
abnormal plasma cell differentiation J:208904
enlarged lymph nodes J:208904
enlarged spleen J:208904
Gt(ROSA)26Sortm1(EWSR1/FLI1)Sbk/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/?

(involves: 129S1/Sv * C57BL/6 * CBA)
abnormal lymph node B cell domain morphology J:129039
abnormal myelopoiesis J:129039
enlarged spleen J:129039
increased leukocyte cell number J:129039
increased spleen red pulp amount J:129039
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Rev3ltm1.1Diaz/Rev3ltm1.1Diaz
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6NTac)
abnormal class switch recombination J:188723
abnormal somatic hypermutation frequency J:188723
decreased B cell proliferation J:188723
immune system phenotype J:188723
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Ighg1tm1(cre)Cgn/Ighg1+
Prdm1tm2Masu/Prdm1tm2Masu

(involves: 129P2/OlaHsd * 129X1/SvJ)
abnormal germinal center B cell physiology J:167612
abnormal plasma cell differentiation J:167612
decreased IgG1 level J:167612
enlarged lymph nodes J:167612
enlarged spleen J:167612
increased germinal center B cell number J:167612
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Il22tm1.1(icre)Stck/Il22+

(involves: 129X1/SvJ * C57BL/6N)
abnormal susceptibility to bacterial infection J:220074
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Plcg1tm1Gcrp/Plcg1tm1Rwen
Tg(Cd4-cre)1Cwi/0

(involves: 129X1/SvJ * C57BL/6 * DBA/2)
abnormal CD4-positive T cell differentiation J:157757
abnormal CD8-positive, alpha-beta T cell differentiation J:157757
abnormal regulatory T cell physiology J:157757
abnormal T cell activation J:157757
decreased CD4-positive, alpha-beta T cell number J:157757
decreased CD8-positive, alpha-beta T cell number J:157757
decreased interferon-gamma secretion J:157757
decreased interleukin-2 secretion J:157757
decreased single-positive T cell number J:157757
decreased T cell number J:157757
decreased T cell proliferation J:157757
dermatitis J:157757
increased double-positive T cell number J:157757
increased T cell apoptosis J:157757
Gt(ROSA)26Sortm1(GNAQ*)Cvrk/Gt(ROSA)26Sor+
Tg(Mitf-cre)7114Gsb/0

(C3FeJ.Cg-Gt(ROSA)26Sortm1(GNAQ*)Cvkr Tg(Mitf-cre)7114Gsb/Cvrk)
enlarged lymph nodes J:225597
Gt(ROSA)26Sortm1(gp80,EGFP)Eces/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+

(either: (involves: 129/Sv * 129P2/OlaHsd * C57BL/6) or (involves: 129/Sv * 129P2/OlaHsd * BALB/c * C57BL/6))
abnormal class switch recombination J:172031
absent spleen germinal center J:172031
decreased B cell apoptosis J:172031
decreased B cell number J:172031
decreased germinal center B cell number J:172031
decreased IgA level J:172031
decreased IgG1 level J:172031
decreased IgG2a level J:172031
decreased IgG3 level J:172031
decreased plasma cell number J:172031
enlarged spleen J:172031
increased B cell number J:172031
increased IgE level J:172031
increased macrophage cell number J:172031
increased marginal zone B cell number J:172031
increased spleen weight J:172031
increased T cell number J:172031
Gt(ROSA)26Sortm1(gp80,EGFP)Eces/Gt(ROSA)26Sor+
Ighg1tm1(cre)Cgn/Ighg1+

(either: (involves: 129/Sv * 129P2/OlaHsd * C57BL/6) or (involves: 129/Sv * 129P2/OlaHsd * BALB/c * C57BL/6))
abnormal class switch recombination J:172031
absent spleen germinal center J:172031
decreased B cell number J:172031
decreased follicular B cell number J:172031
decreased germinal center B cell number J:172031
decreased IgA level J:172031
decreased IgG1 level J:172031
decreased IgG2a level J:172031
decreased IgG2b level J:172031
decreased IgG3 level J:172031
decreased plasma cell number J:172031
enlarged spleen J:172031
increased B cell number J:172031
increased IgE level J:172031
increased macrophage cell number J:172031
increased marginal zone B cell number J:172031
increased spleen weight J:172031
Gt(ROSA)26Sortm1(H1/tetO-RNAi:Pdpk1)Mrl/Gt(ROSA)26Sortm9(cre/ESR1)Arte
Ptentm1Hwu/Ptentm1Hwu

(involves: 129S4/SvJae * C57BL/6)
decreased B cell number J:170965
enlarged lymph nodes J:170965
enlarged spleen J:170965
increased memory B cell number J:170965
increased spleen weight J:170965
Gt(ROSA)26Sortm1(HA)Libl/Gt(ROSA)26Sortm1(HA)Libl
Mogtm1(cre)Gkl/?

(involves: 129/Sv * C57BL/6)
immune system phenotype J:137838
Gt(ROSA)26Sortm1(HA)Libl/Gt(ROSA)26Sortm1(HA)Libl
Mogtm1(cre)Gkl/?
Tg(TcraCl4,TcrbCl4)1Shrm/0

(involves: 129/Sv * BALB/c * C57BL/6)
brain inflammation J:137838
optic nerve inflammation J:137838
spinal cord inflammation J:137838
Gt(ROSA)26Sortm1(HBEGF)Awai/Gt(ROSA)26Sortm1(HBEGF)Awai
Mogtm1(cre)Gkl/?

(involves: C57BL/6)
abnormal immune system physiology J:131076
Gt(ROSA)26Sortm1(HBEGF)Awai/Gt(ROSA)26Sortm1(HBEGF)Awai
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal lymphocyte cell number J:131076
decreased single-positive T cell number J:131076
Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal spleen morphology J:160931
abnormal T cell activation J:160931
abnormal T cell differentiation J:160931
decreased double-positive T cell number J:160931
decreased single-positive T cell number J:160931
decreased T cell number J:160931
enlarged spleen J:160931
immune system phenotype J:160931
increased T cell proliferation J:160931
Gt(ROSA)26Sortm1(MAML1)Wsp/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Tg(Cd4-cre)1Cwi Gt(ROSA)26Sortm1(MAML1)Wsp)
abnormal immunoglobulin level J:113262
abnormal T-helper 1 physiology J:113262
abnormal T-helper 2 physiology J:113262
decreased susceptibility to parasitic infection J:113262
increased susceptibility to parasitic infection J:113262
Gt(ROSA)26Sortm1(MAML1)Wsp/Gt(ROSA)26Sor+
Tg(KRT14-rtTA)F42Efu/0
Tg(tetO-cre)1Jaw/0

(involves: 129 * C57BL/6 * FVB)
conjunctivitis J:194073
Gt(ROSA)26Sortm1(Mirn155)Rsky/Gt(ROSA)26Sortm1(Mirn155)Rsky
(involves: BALB/c * C57BL/6)
abnormal humoral immune response J:121084
increased germinal center B cell number J:121084
Gt(ROSA)26Sortm1(Nfatc2*)Rao/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal interferon level J:148341
abnormal T cell activation J:148341
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Hes1tm1.1Frad/Hes1tm1.1Frad
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJaeSor * C57BL/6 * CBA)
decreased B cell number J:167000
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJaeSor * C57BL/6 * CBA)
decreased B cell number J:167000
enlarged spleen J:167000
increased leukocyte cell number J:167000
Gt(ROSA)26Sortm1(Ntn4)Dyl/Gt(ROSA)26Sor+
Tg(KRT14-cre)1Amc/0

(involves: 129/Sv * C57BL/6 * CBA)
abnormal lymphangiogenesis J:162807
abnormal lymphatic vessel morphology J:162807
lymphatic vessel hyperplasia J:162807
Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal circulating cytokine level J:260047
decreased B cell number J:260047
decreased lymphocyte cell number J:260047
enlarged lymph nodes J:260047
enlarged spleen J:260047
glomerulonephritis J:260047
increased inflammatory response J:260047
increased monocyte cell number J:260047
increased neutrophil cell number J:260047
increased T cell number J:260047
joint inflammation J:260047
small intestinal inflammation J:260047
Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Lyz2tm1(cre)Ifo/Lyz2+
Nlrc4tm1Vmd/Nlrc4tm1Vmd

(involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NCrl)
immune system phenotype J:260047
Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Lyz2tm1(cre)Ifo/Lyz2+
Pycardtm1Vmd/Pycardtm1Vmd

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J)
immune system phenotype J:260047
increased circulating interferon-gamma level J:260047
increased circulating interleukin-6 level J:260047
increased circulating tumor necrosis factor level J:260047
Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Tg(Itgax-cre)1-1Reiz/0

(involves: C3H * C57BL/6 * C57BL/6J)
increased monocyte cell number J:260047
increased neutrophil cell number J:260047
Gt(ROSA)26Sortm1(OVAL/fla,GFP)Vnce/Gt(ROSA)26Sor+
Tg(S100A8-cre,-EGFP)1Ilw/0

(involves: C3H * C57BL/6 * C57BL/6J)
abnormal circulating cytokine level J:260047
increased circulating interleukin-18 level J:260047
increased monocyte cell number J:260047
increased neutrophil cell number J:260047
Gt(ROSA)26Sortm1(Ptpn22*)Draw/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:201448
glomerulonephritis J:201448
increased anti-double stranded DNA antibody level J:201448
increased autoantibody level J:201448
increased B cell number J:201448
increased germinal center B cell number J:201448
spleen hyperplasia J:201448
Gt(ROSA)26Sortm1(RNAi:Bmpr2)Dliu/Gt(ROSA)26Sor+
(involves: 129 * C57BL/6J)
abnormal spleen morphology J:145514
abnormal spleen white pulp morphology J:145514
enlarged spleen J:145514
Gt(ROSA)26Sortm1(rtTA)Awu/Gt(ROSA)26Sortm1(rtTA)Awu
Xisttm1Awu/Y

(involves: 129S4/SvJae)
abnormal B cell differentiation J:112954
abnormal myelopoiesis J:112954
abnormal T cell differentiation J:112954
abnormal thymus morphology J:112954
absent pre-B cells J:112954
decreased double-positive T cell number J:112954
decreased granulocyte number J:112954
decreased immature B cell number J:112954
decreased macrophage cell number J:112954
decreased pro-B cell number J:112954
decreased thymocyte number J:112954
small thymus J:112954
thymus hypoplasia J:112954
Gt(ROSA)26Sortm1(rtTA)Awu/Gt(ROSA)26Sortm1(rtTA)Awu
Xisttm1Awu/Xisttm1Awu

(involves: 129S4/SvJae)
small thymus J:112954
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(CAG-cre)1Nagy/0
Tg(tetO-Vegfa)90Ala/0

(involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR)
enlarged lymph nodes J:99607
thymus atrophy J:99607
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Col2a1-cre)1Bhr/0
Tg(tetO-Vegfa)90Ala/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL)
decreased osteoclast cell number J:156474
enlarged spleen J:156474
Gt(ROSA)26Sortm1(Stat3*A661C*N663C)Sbkv/Gt(ROSA)26Sortm1(Stat3*A661C*N663C)Sbkv
(involves: C57BL/6)
abnormal T-helper 17 cell differentiation J:205858
Gt(ROSA)26Sortm1(Stat3*A661C*N663C)Sbkv/Gt(ROSA)26Sortm1(Stat3*A661C*N663C)Sbkv
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
increased circulating interleukin-17 level J:205858
increased interleukin-17 secretion J:205858
increased regulatory T cell number J:205858
increased T-helper 1 cell number J:205858
increased T-helper 17 cell number J:205858
lung inflammation J:205858
Gt(ROSA)26Sortm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor+
Foxg1tm1(cre)Skm/Foxg1+

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
athymia J:204435
Gt(ROSA)26Sortm1(tTA,tetO-Mir21)Fjsl/Gt(ROSA)26Sor+
Tg(Nes-cre)1Wmz/0

(involves: C57BL/6 * C57BL/6J * SJL/J)
abnormal spleen morphology J:163919
abnormal thymus corticomedullary boundary morphology J:163919
abnormal thymus morphology J:163919
decreased leukocyte cell number J:163919
enlarged lymph nodes J:163919
enlarged spleen J:163919
enlarged thymus J:163919
intermingled spleen red and white pulp J:163919
Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/Gt(ROSA)26Sor+
Tg(Nes-cre)1Wmz/0

(involves: 129 * C57BL/6 * FVB/N * SJL/J)
abnormal immune system morphology J:185598
enlarged lymph nodes J:185598
enlarged spleen J:185598
increased spleen weight J:185598
increased spleen white pulp amount J:185598
thymus hyperplasia J:185598
Gt(ROSA)26Sortm1.1(Aco1*)Mwh/Gt(ROSA)26Sortm1.1(Aco1*)Mwh
(B6.129P2(129S1)-Gt(ROSA)26Sortm1.1(Aco1*)Mwh)
increased spleen iron level J:196374
Gt(ROSA)26Sortm1.1(CAG-PSTPIP1)Dtg/Gt(ROSA)26Sor+
(involves: BALB/cJ * C57BL/6)
immune system phenotype J:196002
Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz/Gt(ROSA)26Sortm1.1(CAG-Trp53*,-EGFP)Medz
(involves: C57BL/6)
decreased thymocyte apoptosis J:158953
Gt(ROSA)26Sortm1.1(DUX4*)Plj/Gt(ROSA)26Sor+
(B6(Cg)-Gt(ROSA)26Sortm1.1(DUX4*)Plj)
enlarged lymph nodes J:256652
enlarged popliteal lymph nodes J:256652
Gt(ROSA)26Sortm1.1(DUX4*)Plj/Gt(ROSA)26Sor+
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129S/SvEv * C57BL/6)
enlarged lymph nodes J:256652
enlarged popliteal lymph nodes J:256652
Gt(ROSA)26Sortm1.1(DUX4*)Plj/Gt(ROSA)26Sor+
Tg(ACTA1-cre/Esr1*)2Kesr/0

(involves: C3H * C57BL/6)
increased acute inflammation J:256652
Gt(ROSA)26Sortm1.1(DUX4*)Plj/Gt(ROSA)26Sortm1.1(DUX4*)Plj
(B6(Cg)-Gt(ROSA)26Sortm1.1(DUX4*)Plj)
preputial gland inflammation J:256652
Gt(ROSA)26Sortm1.1(Loxl2)Acan/Gt(ROSA)26Sortm1.1(Loxl2)Acan
(Not Specified)
epididymis inflammation J:220689
increased inflammatory response J:220689
Gt(ROSA)26Sortm1.1(Ubc-BCL3)Sbn/Gt(ROSA)26Sor+
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6)
decreased B cell proliferation J:207111
decreased follicular B cell number J:207111
decreased marginal zone B cell number J:207111
increased follicular B cell number J:207111
Gt(ROSA)26Sortm1.1(Wls/YFP)Mbtr/Gt(ROSA)26Sor+
(involves: C57BL/6)
decreased neutrophil cell number J:202499
Gt(ROSA)26Sortm1.2(CAG-PLS3,-GFP)Bwir/Gt(ROSA)26Sor+
(B6N.Cg-Gt(ROSA)26Sortm1.1(CAG-PLS3,-GFP)Bwir)
decreased osteoclast cell number J:267292
Gt(ROSA)26Sortm1Fia/Gt(ROSA)26Sor+
Nf1tm1Fcr/Nf1tm1Par
Tg(Tek-cre)1Ywa/0

(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
abnormal spleen morphology J:114455
Gt(ROSA)26Sortm1Jus/Gt(ROSA)26Sor+
Tg(Lck-icre)3779Nik/0

(involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA/2)
immune system phenotype J:202090
Gt(ROSA)26Sortm1Jus/Gt(ROSA)26Sor+
Tg(MMTV-cre)4Mam/0

(involves: C57BL/6J * C57BL/6N * FVB/N)
abnormal leukocyte morphology J:202090
abnormal thymus physiology J:202090
arrested B cell differentiation J:202090
decreased B cell number J:202090
decreased double-positive T cell number J:202090
decreased mature B cell number J:202090
decreased pre-B cell number J:202090
decreased pro-B cell number J:202090
enlarged lymph nodes J:202090
enlarged spleen J:202090
enlarged thymus J:202090
increased CD8-positive, alpha-beta T cell number J:202090
increased inflammatory response J:202090
increased large unstained cell number J:202090
increased leukocyte cell number J:202090
increased single-positive T cell number J:202090
intermingled spleen red and white pulp J:202090
intestinal inflammation J:202090
kidney inflammation J:202090
liver inflammation J:202090
meningitis J:202090
stomach inflammation J:202090
Gt(ROSA)26Sortm1Jus/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA)
abnormal leukocyte morphology J:202090
abnormal thymus physiology J:202090
arrested B cell differentiation J:202090
decreased B cell number J:202090
decreased double-positive T cell number J:202090
decreased mature B cell number J:202090
decreased pre-B cell number J:202090
decreased pro-B cell number J:202090
enlarged lymph nodes J:202090
enlarged spleen J:202090
enlarged thymus J:202090
increased CD8-positive, alpha-beta T cell number J:202090
increased inflammatory response J:202090
increased large unstained cell number J:202090
increased leukocyte cell number J:202090
increased single-positive T cell number J:202090
intermingled spleen red and white pulp J:202090
intestinal inflammation J:202090
kidney inflammation J:202090
liver inflammation J:202090
meningitis J:202090
stomach inflammation J:202090
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Id3tm2.1Zhu/Id3tm2.1Zhu
Tg(Lck-cre)#Zhu/0

(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL)
decreased T cell number J:172701
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa
Prox1tm3(cre/ERT2)Gco/Prox1+

(involves: 129S1/Sv * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6)
abnormal lymphatic vessel morphology J:158959
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Tbx1tm3.1Bld/Tbx1tm6(cre)Bld

(involves: 129S4/SvJaeSor * 129S7/SvEvBrd)
abnormal lymphatic vessel morphology J:159824
Gt(ROSA)26Sortm2(CAG-Notch2*)Uzs/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J)
abnormal B cell differentiation J:179036
abnormal marginal zone B cell physiology J:179036
abnormal spleen marginal zone morphology J:179036
decreased B cell number J:179036
decreased B-1a cell number J:179036
decreased B-2 B cell number J:179036
decreased follicular B cell number J:179036
decreased IgG1 level J:179036
decreased IgG3 level J:179036
decreased IgM level J:179036
decreased spleen B cell follicle size J:179036
decreased spleen germinal center number J:179036
decreased transitional stage T2 B cell number J:179036
increased B cell proliferation J:179036
increased marginal zone B cell number J:179036
increased spleen weight J:179036
increased T cell number J:179036
increased transitional stage T1 B cell number J:179036
Gt(ROSA)26Sortm2(CAG-Notch2*)Uzs/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19tm1(cre)Cgn

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J)
abnormal B cell differentiation J:179036
abnormal spleen marginal zone morphology J:179036
decreased follicular B cell number J:179036
decreased mature B cell number J:179036
decreased pre-B cell number J:179036
decreased transitional stage T2 B cell number J:179036
increased marginal zone B cell number J:179036
increased transitional stage T1 B cell number J:179036
Gt(ROSA)26Sortm2(CAG-Notch2*)Uzs/Gt(ROSA)26Sor+
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S6/SvEvTac * BALB/c * C57BL/6J)
arrested B cell differentiation J:179036
decreased B cell number J:179036
decreased splenocyte number J:179036
increased T cell number J:179036
Gt(ROSA)26Sortm2(CAG-Nr5a1)Fjd/Gt(ROSA)26Sor+
Pgrtm2(cre)Lyd/Pgr+

(involves: 129S1/Sv * 129X1/SvJ)
uterus inflammation J:269597
Gt(ROSA)26Sortm2(CAG-PSTPIP1*)Dtg/Gt(ROSA)26Sor+
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
immune system phenotype J:196002
Gt(ROSA)26Sortm2(cre/ERT2)Brn/0
Tg(Sftpc-Grem1)105Mmyl/0

(involves: 129P2/OlaHsd * C57BL/6N)
lung inflammation J:82809
Gt(ROSA)26Sortm2(H1/tetO-RNAi:Kdm1a)Arte/Gt(ROSA)26Sor+
(involves: C57BL/6)
abnormal granulocyte differentiation J:192055
abnormal monocyte differentiation J:192055
enlarged spleen J:192055
increased leukocyte cell number J:192055
Gt(ROSA)26Sortm2(ITK/Syk)Hjum/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal circulating cytokine level J:207306
abnormal cytokine secretion J:207306
abnormal immunoglobulin level J:207306
abnormal spleen morphology J:207306
enlarged spleen J:207306
immune system phenotype J:207306
increased activated T cell number J:207306
increased CD4-positive, alpha-beta T cell number J:207306
increased circulating interferon-gamma level J:207306
increased circulating interleukin-2 level J:207306
increased circulating interleukin-4 level J:207306
increased circulating interleukin-6 level J:207306
increased circulating interleukin-10 level J:207306
increased circulating tumor necrosis factor level J:207306
increased IgA level J:207306
increased IgG level J:207306
increased IgM level J:207306
increased inflammatory response J:207306
increased interferon-gamma secretion J:207306
increased interleukin-2 secretion J:207306
increased interleukin-4 secretion J:207306
increased interleukin-6 secretion J:207306
increased interleukin-10 secretion J:207306
increased mature B cell number J:207306
increased plasma cell number J:207306
increased tumor necrosis factor secretion J:207306
Gt(ROSA)26Sortm2(ITK/Syk)Hjum/Gt(ROSA)26Sor+
Tg(Lck-cre)I57Jxm/0

(involves: 129S6/SvEvTac * ICR)
abnormal circulating cytokine level J:207306
abnormal cytokine secretion J:207306
abnormal immunoglobulin level J:207306
abnormal spleen morphology J:207306
enlarged spleen J:207306
immune system phenotype J:207306
increased activated T cell number J:207306
increased CD4-positive, alpha-beta T cell number J:207306
increased circulating interferon-gamma level J:207306
increased circulating interleukin-2 level J:207306
increased circulating interleukin-4 level J:207306
increased circulating interleukin-6 level J:207306
increased circulating interleukin-10 level J:207306
increased circulating tumor necrosis factor level J:207306
increased IgA level J:207306
increased IgG level J:207306
increased IgM level J:207306
increased inflammatory response J:207306
increased interferon-gamma secretion J:207306
increased interleukin-2 secretion J:207306
increased interleukin-4 secretion J:207306
increased interleukin-6 secretion J:207306
increased interleukin-10 secretion J:207306
increased mature B cell number J:207306
increased plasma cell number J:207306
increased tumor necrosis factor secretion J:207306
Gt(ROSA)26Sortm2(Lmp1/CD40)Uzs/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal B cell activation J:137122
abnormal B cell physiology J:137122
abnormal class switch recombination J:137122
abnormal humoral immune response J:137122
abnormal T cell activation J:137122
enlarged inguinal lymph nodes J:137122
enlarged spleen J:137122
increased B cell number J:137122
increased B cell proliferation J:137122
increased follicular B cell number J:137122
increased marginal zone B cell number J:137122
increased spleen B cell follicle size J:137122
increased spleen weight J:137122
increased T cell number J:137122
Gt(ROSA)26Sortm2(Lmp1/CD40)Uzs/Gt(ROSA)26Sor+
Tg(Cr2-cre)3Cgn/0

(involves: BALB/c * C57BL/6)
abnormal immune system morphology J:137122
abnormal immune system physiology J:137122
Gt(ROSA)26Sortm2(Mirn150)Rsky/Gt(ROSA)26Sor+
(involves: C57BL/6 * SJL/J)
decreased mature B cell number J:127234
Gt(ROSA)26Sortm2(Mirn150)Rsky/Gt(ROSA)26Sortm2(Mirn150)Rsky
(involves: C57BL/6 * SJL/J)
decreased B-1 B cell number J:127234
decreased B-2 B cell number J:127234
decreased CD4-positive, alpha-beta T cell number J:127234
decreased CD8-positive, alpha-beta T cell number J:127234
increased B cell apoptosis J:127234
Gt(ROSA)26Sortm2(Nfatc2*)Rao/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal interferon level J:148341
abnormal T cell activation J:148341
Gt(ROSA)26Sortm2(sb11)Njen/Gt(ROSA)26Sor+
TgTn(sb-T2/Onc2)6070Njen/0

(involves: 129 * C57BL/6 * C57BL/6J)
increased susceptibility to infection J:153656
Gt(ROSA)26Sortm2.1(CAG-PSTPIP1*)Dtg/Gt(ROSA)26Sor+
(involves: BALB/cJ * C57BL/6)
increased circulating interleukin-1 alpha level J:196002
increased circulating interleukin-1 beta level J:196002
increased circulating tumor necrosis factor level J:196002
Gt(ROSA)26Sortm2.1(Cd74/MOG)Awai/Gt(ROSA)26Sor+
(involves: C57BL/6 * BALB/cJ)
abnormal humoral immune response J:140751
decreased susceptibility to experimental autoimmune encephalomyelitis J:140751
Gt(ROSA)26Sortm2.1(Mirn150)Rsky/Gt(ROSA)26Sor+
(involves: C57BL/6 * SJL/J)
decreased mature B cell number J:127234
Gt(ROSA)26Sortm2.1(Mirn150)Rsky/Gt(ROSA)26Sortm2.1(Mirn150)Rsky
(involves: C57BL/6 * SJL/J)
arrested B cell differentiation J:127234
arrested T cell differentiation J:127234
decreased B-1 B cell number J:127234
decreased B-2 B cell number J:127234
decreased lymphocyte cell number J:127234
increased B cell apoptosis J:127234
Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+
Lef1tm1Hhx/Lef1tm1Hhx
Tg(GZMB-cre)1Jcb/0

(involves: 129S4/SvJaeSor * C57BL/6 * FVB/N)
abnormal memory T cell physiology J:189838
decreased CD8-positive, alpha-beta T cell number J:189838
Gt(ROSA)26Sortm3(CAG-EYFP)Hze/Gt(ROSA)26Sor+
Stat5atm2Mam Stat5btm1Mam/Del(11Stat5a-Stat5b)1Mam
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA)
abnormal CD4-positive T cell differentiation J:204829
Gt(ROSA)26Sortm3(CAG-Il17a)Awai/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal immune system physiology J:144710
abnormal neutrophil physiology J:144710
increased circulating interleukin-17 level J:144710
increased granulocyte number J:144710
increased interleukin-17 secretion J:144710
Gt(ROSA)26Sortm3(CAG-MIR17-92,-EGFP)Rsky/Gt(ROSA)26Sor+
Tg(CD2-icre)4Kio/0

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
decreased marginal zone B cell number J:133215
increased B-1a cell number J:133215
Gt(ROSA)26Sortm3(CAG-MIR17-92,-EGFP)Rsky/Gt(ROSA)26Sortm3(CAG-MIR17-92,-EGFP)Rsky
Tg(CD2-icre)4Kio/0

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
abnormal B cell activation J:133215
abnormal B cell morphology J:133215
abnormal CD4-positive, alpha beta T cell morphology J:133215
abnormal CD4-positive, alpha-beta T cell physiology J:133215
abnormal immune system morphology J:133215
abnormal immune system physiology J:133215
abnormal immunoglobulin level J:133215
abnormal spleen marginal zone morphology J:133215
abnormal T cell activation J:133215
abnormal T cell differentiation J:133215
decreased marginal zone B cell number J:133215
decreased spleen red pulp amount J:133215
enlarged lymph nodes J:133215
immune system phenotype J:133215
increased anti-double stranded DNA antibody level J:133215
increased anti-single stranded DNA antibody level J:133215
increased B cell number J:133215
increased B cell proliferation J:133215
increased B-1a cell number J:133215
increased CD4-positive, alpha-beta T cell number J:133215
increased CD8-positive, alpha-beta T cell number J:133215
increased germinal center B cell number J:133215
increased IgG2a level J:133215
increased IgG2b level J:133215
increased IgG3 level J:133215
increased IgM level J:133215
increased lymphocyte cell number J:133215
increased spleen weight J:133215
increased spleen white pulp amount J:133215
intermingled spleen red and white pulp J:133215
lymph node hyperplasia J:133215
spleen hyperplasia J:133215
Gt(ROSA)26Sortm3.1(CAG-Il17a)Awai/Gt(ROSA)26Sor+
(involves: BALB/c * C57BL/6)
increased granulocyte number J:144710
increased interleukin-17 secretion J:144710
skin inflammation J:144710
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Hnrnpltm1.1Tmo/Hnrnpltm1.1Tmo
Tg(Lck-cre)548Jxm/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal T cell differentiation J:188749
Gt(ROSA)26Sortm4(CAG-hsb5)Nki/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0
Tg(Tal1-tTA)19Dgt/0
Tg(tetO-BCR/ABL1)2Dgt/0
TgTn(pb-sb-GrOnc)#aGsva/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA/J * DBA/2 * FVB/N)
increased basophil cell number J:227558
increased granulocyte number J:227558
increased leukocyte cell number J:227558
increased spleen weight J:227558
Gt(ROSA)26Sortm4(H1/tetO-RNAi:Ezh2)Arte/Gt(ROSA)26Sor+
(C57BL/6-Gt(ROSA)26Sortm4(H1/tetO-RNAi:Ezh2)Arte)
small lymph nodes J:202724
Gt(ROSA)26Sortm4(HIF2A*)Kael/Gt(ROSA)26Sortm4(HIF2A*)Kael
Tg(Vil1-cre/ERT2)23Syr/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
increased susceptibility to colitis induced morbidity/mortality J:307422
Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:167612
decreased germinal center B cell number J:167612
enlarged spleen J:167612
increased B cell number J:167612
increased IgG1 level J:167612
increased IgM level J:167612
increased plasma cell number J:167612
Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sor+
Ighg1tm1(cre)Cgn/Ighg1+
Prdm1tm2Masu/Prdm1tm2Masu

(involves: 129P2/OlaHsd * C57BL/6)
abnormal germinal center B cell physiology J:167612
abnormal plasma cell differentiation J:167612
decreased IgG1 level J:167612
increased germinal center B cell number J:167612
Gt(ROSA)26Sortm4(Ikbkb)Rsky/Gt(ROSA)26Sortm4(Ikbkb)Rsky
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * C57BL/6)
increased B cell number J:157297
Gt(ROSA)26Sortm4(Wnt7b)Flng/Gt(ROSA)26Sor+
Tg(Col1a1-cre)1Ack/0

(involves: FVB/N)
decreased osteoclast cell number J:208766
enlarged spleen J:208766
increased spleen weight J:208766
Gt(ROSA)26Sortm4(Wnt7b)Flng/Gt(ROSA)26Sor+
Tg(Runx2-rtTA*M2)#Flng/0
Tg(tetO-cre)1Jaw/0

(involves: 129 * C57BL/6)
decreased osteoclast cell number J:208766
Gt(ROSA)26Sortm5(H1/tetO-RNAi:Ezh2)Arte/Gt(ROSA)26Sor+
(C57BL/6-Gt(ROSA)26Sortm5(H1/tetO-RNAi:Ezh2)Arte)
small lymph nodes J:202724
Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky/Gt(ROSA)26Sor+
Tg(CAG-cre/Esr1*)5Amc/0

(B6.Cg-Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky Tg(CAG-cre/Esr1*)5Amc)
abnormal spleen morphology J:264410
enlarged lymphatic vessel J:264410
Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky/Gt(ROSA)26Sortm13(CAG-MYC,-CD2*)Rsky
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:191824
increased germinal center B cell number J:191824
Gt(ROSA)26Sortm8(Map2k1*,EGFP)Rsky/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0
Traf3ip3tm1c(KOMP)Wtsi/Traf3ip3tm1c(KOMP)Wtsi

(involves: C57BL/6 * C57BL/6N * DBA/2)
immune system phenotype J:226431
Gt(ROSA)26Sortm8(Map2k1*,EGFP)Rsky/Gt(ROSA)26Sortm8(Map2k1*,EGFP)Rsky
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased mature B cell number J:157297
Gt(ROSA)26Sortm9(cre/ESR1)Arte/?
Tnfaip3tm1Homy/Tnfaip3tm1Homy

(involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac)
abnormal circulating cytokine level J:212681
abnormal circulating interleukin level J:212681
increased circulating interferon-gamma level J:212681
increased circulating interleukin-1 beta level J:212681
increased circulating interleukin-6 level J:212681
increased circulating tumor necrosis factor level J:212681
pale spleen J:212681
thymus atrophy J:212681
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Map3k14tm1.1Gne/Map3k14tm1.1Gne

(B6(Cg)-Map3k14tm1.1Gne Gt(ROSA)26Sortm9(cre/ESR1)Arte)
abnormal immunoglobulin level J:240453
decreased B cell number J:240453
decreased B cell proliferation J:240453
decreased germinal center B cell number J:240453
decreased IgA level J:240453
decreased IgG1 level J:240453
decreased IgM level J:240453
decreased Peyer's patch number J:240453
immune system phenotype J:240453
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Ptentm1Hwu/Ptentm1Hwu

(involves: 129S4/SvJae * C57BL/6)
enlarged lymph nodes J:170965
enlarged spleen J:170965
increased spleen weight J:170965
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Ripk3tm1Arte/Ripk3tm1Arte

(involves: C57BL/6NTac)
abnormal lymphocyte morphology J:209137
intestinal inflammation J:209137
thymus atrophy J:209137
Gt(ROSA)26Sortm9(Rac1*,EGFP)Rsky/Gt(ROSA)26Sortm9(Rac1*,EGFP)Rsky
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased mature B cell number J:157297
Gt(ROSA)26Sortm10(Lmp1)Rsky/Gt(ROSA)26Sor+
(involves: BALB/cJ)
abnormal B cell morphology J:181546
increased B cell proliferation J:181546
Gt(ROSA)26Sortm10(Lmp1)Rsky/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * BALB/cJ)
abnormal B cell differentiation J:181546
abnormal CD8-positive, alpha-beta T cell physiology J:181546
abnormal immune system physiology J:181546
decreased B cell number J:181546
decreased mature B cell number J:181546
decreased pre-B cell number J:181546
enlarged spleen J:181546
increased B cell number J:181546
increased B cell proliferation J:181546
increased CD4-positive, alpha-beta T cell number J:181546
increased CD8-positive, alpha-beta T cell number J:181546
increased pro-B cell number J:181546
Gt(ROSA)26Sortm10(Lmp1)Rsky/Gt(ROSA)26Sor+
Tcrbtm1Mom/Tcrb+
Tcrdtm1Mom/Tcrdtm1Mom
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S2/SvPas * BALB/cJ)
enlarged spleen J:181546
increased B cell number J:181546
Gt(ROSA)26Sortm10(Lmp1)Rsky/Gt(ROSA)26Sor+
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S2/SvPas * BALB/cJ)
enlarged spleen J:181546
increased B cell number J:181546
Gt(ROSA)26Sortm11(Lmp1)Rsky/Gt(ROSA)26Sor+
(involves: C57BL/6)
abnormal B cell morphology J:181546
increased B cell proliferation J:181546
Gt(ROSA)26Sortm11(Lmp1)Rsky/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:181546
abnormal CD4-positive, alpha-beta T cell physiology J:181546
abnormal CD8-positive, alpha-beta T cell physiology J:181546
abnormal immune system physiology J:181546
decreased B cell number J:181546
decreased mature B cell number J:181546
decreased pre-B cell number J:181546
enlarged spleen J:181546
increased B cell number J:181546
increased B cell proliferation J:181546
increased CD4-positive, alpha-beta T cell number J:181546
increased CD8-positive, alpha-beta T cell number J:181546
increased interferon-gamma secretion J:181546
increased pro-B cell number J:181546
increased tumor necrosis factor secretion J:181546
Gt(ROSA)26Sortm11(Lmp1)Rsky/Gt(ROSA)26Sor+
Cd19tm1(cre/ERT2)Rsky/Cd19+

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal T cell physiology J:217520
enlarged spleen J:217520
increased activated T cell number J:217520
increased B cell number J:217520
increased CD4-positive, alpha-beta T cell number J:217520
increased CD8-positive, alpha-beta T cell number J:217520
Gt(ROSA)26Sortm11(Lmp1)Rsky/Gt(ROSA)26Sor+
Tcrbtm1Mom/Tcrb+
Tcrdtm1Mom/Tcrdtm1Mom
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
enlarged spleen J:181546
increased B cell number J:181546
Gt(ROSA)26Sortm11(Lmp1)Rsky/Gt(ROSA)26Sor+
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
enlarged spleen J:181546
increased B cell number J:181546
Gt(ROSA)26Sortm12(CD2*)Rsky/Gt(ROSA)26Sor+
Myctm2Fwa/Myctm2Fwa
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6)
decreased spleen germinal center size J:188564
Gt(ROSA)26Sortm13(CAG-MYC,-CD2*)Rsky/Gt(ROSA)26Sor+
Myctm2Fwa/Myctm2Fwa
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6)
immune system phenotype J:188564
Gtpbp2tm1b(KOMP)Mbp/Gtpbp2+
(C57BL/6N-Gtpbp2tm1b(KOMP)Mbp/Ucd)
enlarged lymph nodes J:211773
Gtpbp2tm1b(KOMP)Mbp/Gtpbp2tm1b(KOMP)Mbp
(C57BL/6N-Gtpbp2tm1b(KOMP)Mbp/Ucd)
enlarged lymph nodes J:211773
Gtsf1lem1(IMPC)J/Gtsf1lem1(IMPC)J
(C57BL/6NJ-Gtsf1lem1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Guca2aem1(IMPC)Mbp/Guca2aem1(IMPC)Mbp
(C57BL/6N-Guca2aem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Gucy1b1tm1.1Frb/Gucy1b1tm1.1Frb
(involves: 129 * C57BL/6 * FVB/N)
peritoneal inflammation J:121321
Gucy2ctm1Gar/Gucy2ctm1Gar
(either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6J))
decreased susceptibility to bacterial infection J:43046
decreased susceptibility to bacterial infection induced morbidity/mortality J:43046
Gucy2ctm1Gian/Gucy2ctm1Gian
(involves: 129P2/OlaHsd * Black Swiss)
decreased susceptibility to infection J:43682
Guloem1(IMPC)Ccpcz/Guloem1(IMPC)Ccpcz
(C57BL/6NCrl-Guloem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Gulosfx/Gulosfx
(BALB/cBy-Gulosfx/J)
abnormal osteoclast differentiation J:66648
small spleen J:66648
small thymus J:66648
Gvhd1C57BL/10J/Gvhd1C57BL/10J
(involves: B10.D2-H2d * C57BL/10J)
increased susceptibility to graft versus host disease J:52834
Gvhd1C57BL/10J/Gvhd1C57BL/10J
Gvhd2C57BL/10J/Gvhd2C57BL/10J

(involves: B10.D2-H2d * C57BL/10J)
increased susceptibility to graft versus host disease J:52834
Gvhd2C57BL/10J/Gvhd2C57BL/10J
(involves: B10.D2-H2d * DBA/2J)
increased susceptibility to graft versus host disease J:52834
Gvhd4DBA/2J/Gvhd4DBA/2J
(involves: C57BL/10 * DBA/2J)
increased anti-single stranded DNA antibody level J:66655
Gvhd4DBA/2J/Gvhd4DBA/2J
Gvhd5DBA/2J/Gvhd5DBA/2J

(involves: C57BL/10 * DBA/2J)
increased anti-single stranded DNA antibody level J:66655
Gvhd5DBA/2J/Gvhd5DBA/2J
(involves: C57BL/10 * DBA/2J)
increased anti-single stranded DNA antibody level J:66655
Gy/Y
(involves: 101/H * C3H/HeH)
blepharitis J:8335
Gzmatm1Ley/Gzmatm1Ley
(involves: 129X1/SvJ * C57BL/6)
decreased cytotoxic T cell cytolysis J:49361
Gzmatm1Simn/Gzmatm1Simn
(B6.Cg-Gzmatm1Simn)
immune system phenotype J:92718, J:28773
Gzmatm1Simn/Gzmatm1Simn
Gzmbtm1Ley/Gzmbtm1Ley

(involves: 129S2/SvPas * C57BL/6)
abnormal leukocyte physiology J:44204
immune system phenotype J:44204
Gzmatm1Simn/Gzmatm1Simn
Gzmbtm1Ley/Gzmbtm1Ley

(B6.Cg-Gzmatm1Simn Gzmbtm1Ley)
immune system phenotype J:92718
increased susceptibility to Flaviviridae infection J:90852
increased susceptibility to parasitic infection J:81397
Gzmatm1Simn/Gzmatm1Simn
Gzmbtm1Ley/Gzmbtm1Ley
Prf1tm1Sdz/Prf1tm1Sdz

(B6.Cg-Gzmatm1Simn Gzmbtm1Ley Prf1tm1Sdz)
immune system phenotype J:92718
increased susceptibility to Flaviviridae infection J:90852
increased susceptibility to parasitic infection J:81397
Gzmbtm1Asmv/Gzmbtm1Asmv
(involves: C57BL/6)
immune system phenotype J:203720
Gzmbtm1Ley/Gzmbtm1Ley
(involves: 129S2/SvPas * C57BL/6J)
decreased cytotoxic T cell cytolysis J:23560
Gzmbtm1Ley/Gzmbtm1Ley
(B6.129S2-Gzmbtm1Ley)
impaired natural killer cell mediated cytotoxicity J:113213
Gzmbtm1Ley/Gzmbtm1Ley
(involves: 129X1/SvJ)
abnormal NK cell physiology J:126114
decreased T cell apoptosis J:126114
Gzmbtm1Ley/Gzmbtm1Ley
Serpinb9tm1.1Pib/Serpinb9tm1.1Pib

(involves: 129S2/SvPas * BALB/cJ * C57BL/6J)
decreased cytotoxic T cell apoptosis J:252016
Gzmbtm1Ley/Gzmbtm1Ley
Serpinb9tm1Arp/Serpinb9tm1Arp

(involves: 129S2/SvPas * C57BL/6)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:113349
abnormal cytotoxic T cell physiology J:113349
Gzmbtm2.1Ley/Gzmbtm2.1Ley
(129X1/SvJ-Gzmbtm2.1Ley)
decreased cytotoxic T cell cytolysis J:96538
Gzmbtm2Ley/Gzmbtm2Ley
(129X1/SvJ-Gzmbtm2Ley)
abnormal immune system physiology J:96538
decreased cytotoxic T cell cytolysis J:96538
Gzmktm1.1Pib/Gzmktm1.1Pib
(B6(Cg)-Gzmktm1.1Pib)
immune system phenotype J:302067
Gzmmtm1(cre)Mjs/Gzmmtm1(cre)Mjs
(C57BL/6-Gzmmtm1(cre)Mjs)
increased susceptibility to Herpesvirales infection J:113213
H1f0tm1Ais/H1f0tm1Ais
H1f2tm2Ais/H1f2tm2Ais
H1f4tm2Ais/H1f4tm2Ais

(involves: 129/Sv * C57BL/6 * SJL)
small thymus J:83954
H1f2tm2Ais/H1f2tm2Ais
H1f3tm2Ais/H1f3+
H1f4tm2Ais/H1f4tm2Ais

(involves: 129/Sv * C57BL/6 * SJL)
small thymus J:83954
H2-Aab-tm1Blt/H2-Aab-tm1Blt
(C57BL/6-H2-Aab-tm1Blt)
abnormal MHC II cell surface expression on macrophages J:67924
abnormal splenocyte physiology J:16372
abnormal T cell morphology J:16372
decreased CD4-positive, alpha-beta T cell number J:16372
enlarged lymph nodes J:16372
enlarged thymus J:16372
increased CD8-positive, alpha-beta T cell number J:16372
thymus hyperplasia J:16372
H2-Ab1b-tm1.1Jssh/H2-Ab1b-tm1.1Jssh
(C57BL/6-H2-Ab1b-tm1.1Jssh)
abnormal dendritic cell antigen presentation J:201198
abnormal T cell differentiation J:201198
decreased regulatory T cell number J:201198
H2-Ab1b-tm1.1Sish/H2-Ab1b-tm1.1Sish
(involves: 129S1/Sv * 129X1/SvJ)
abnormal dendritic cell physiology J:157516
decreased interleukin-12 secretion J:157516
decreased tumor necrosis factor secretion J:157516
H2-Ab1b-tm1Doi/H2-Ab1+
(involves: 129S2/SvPas * C57BL/6 * NOD/Lt)
insulitis J:93557
H2-Ab1b-tm1Doi/H2-Ab1b-tm1Doi
(involves: 129S2/SvPas * C57BL/6)
abnormal B cell physiology J:65736
abnormal CD4-positive, alpha beta T cell morphology J:65736
abnormal CD4-positive, alpha-beta T cell physiology J:65736
abnormal cytokine secretion J:64283
abnormal immune system cell morphology J:65736
abnormal immune system morphology J:65736
abnormal immune system organ morphology J:65736
abnormal immune system physiology J:65736
abnormal lymph node cell ratio J:65736
abnormal spleen B cell follicle morphology J:65736
abnormal spleen marginal zone morphology J:65736
abnormal spleen morphology J:65736
abnormal spleen periarteriolar lymphoid sheath morphology J:65736
abnormal T cell physiology J:65736
absent spleen germinal center J:65736
decreased CD4-positive, alpha-beta T cell number J:51885, J:65736
decreased IgG1 level J:65736
decreased susceptibility to parasitic infection J:64283
increased CD4-positive, alpha-beta T cell number J:64283
increased CD8-positive, alpha-beta T cell number J:65736, J:64283
increased susceptibility to parasitic infection J:64283
H2-Ab1b-tm1Doi/H2-Ab1b-tm1Doi
(involves: 129S2/SvPas * C57BL/6 * NOD/Lt)
insulitis J:93557
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
(involves: 129S2/SvPas * C57BL/6J)
abnormal humoral immune response J:74418
abnormal response to transplant J:91742
decreased CD4-positive, alpha-beta T cell number J:74418
decreased IgG level J:74418
increased CD8-positive, alpha-beta T cell number J:74418
increased IgM level J:74418
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
(NOD.129S2-H2-Ab1b-tm1Gru)
immune system phenotype J:86540
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
(B6.129S2-H2-Ab1b-tm1Gru)
abnormal B cell physiology J:91341
abnormal lymphocyte physiology J:91341
decreased CD4-positive, alpha-beta T cell number J:91341
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
(involves: 129S2/SvPas * C57BL/6)
abnormal level of surface class II molecules J:67941
decreased CD4-positive, alpha-beta T cell number J:67941
decreased IgG1 level J:67941
decreased IgM level J:67941
decreased single-positive T cell number J:67941
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Ighmtm1Cgn/Ighmtm1Cgn
Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell

(NOD.Cg-Ighmtm1Cgn H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell)
heart inflammation J:113267
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Rag1tm1Mom/Rag1tm1Mom
Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell

(NOD.Cg-Rag1tm1Mom H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell)
abnormal response to transplant J:113267
heart inflammation J:113267
increased autoantibody level J:113267
myocarditis J:113267
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Rag1tm1Mom/Rag1tm1Mom
Tg(HLA-DQA1,HLA-DQB1)73Myl/0

(NOD.Cg-Rag1tm1Mom H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)73Myl)
abnormal response to transplant J:88055
myocarditis J:88055
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Runx1tm1Toku/Runx1tm1Toku
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/2)
abnormal interferon secretion J:131081
increased CD4-positive, alpha-beta T cell number J:131081
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tespa1tm1Smoc/Tespa1tm1Smoc

(involves: 129 * 129S2/SvPas * C57BL/6)
absent CD4-positive, alpha-beta T cells J:186446
decreased CD8-positive, alpha-beta T cell number J:186446
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(Ab1TL)1Gru/0

(B6.Cg-H2-Ab1b-tm1Gru Tg(Ab1TL)1Gru)
abnormal CD4-positive T cell differentiation J:91341
abnormal macrophage antigen presentation J:91341
abnormal professional antigen presenting cell physiology J:91341
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell

(NOD.Cg-H2-Ab1b-tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell)
autoimmune response J:87013, J:86540
decreased susceptibility to autoimmune disorder J:87013
heart inflammation J:87013, J:86540
immune system phenotype J:87013
increased autoantibody level J:113267
lung inflammation J:86540
myositis J:86540
salivary gland inflammation J:86540
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell/Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell

(NOD.Cg-H2-Ab1b-tm1Gru Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell)
immune system phenotype J:113267
increased autoantibody level J:113509
thyroid gland inflammation J:113509
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)1Dv/0
Tg(HLA-DRB1)31Dmz/0
Tg(Ins2-CD80)3B7Flv/0

(involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA * SJL)
abnormal CD4-positive, alpha beta T cell morphology J:68641
abnormal CD8-positive, alpha beta T cell morphology J:68641
decreased susceptibility to autoimmune diabetes J:68641
salivary gland inflammation J:68641
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)1Dv/0
Tg(Ins2-CD80)3B7Flv/0

(B6.Cg-H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv)
increased susceptibility to autoimmune diabetes J:59245
salivary gland inflammation J:59245
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)1Dv/0
Tg(Ins2-CD80)3B7Flv/0

(involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA)
decreased interleukin-6 secretion J:68641
increased interferon-gamma secretion J:68641
increased susceptibility to autoimmune diabetes J:68641
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)70Myl/0

(NOD.Cg-H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)70Myl)
heart inflammation J:88055
increased autoantibody level J:88055
insulitis J:88055
myocarditis J:88055
salivary gland inflammation J:88055
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DQA1,HLA-DQB1)73Myl/0

(NOD.Cg-H2-Ab1b-tm1Gru Tg(HLA-DQA1,HLA-DQB1)73Myl)
heart inflammation J:88055
increased autoantibody level J:88055
insulitis J:88055
myocarditis J:88055
salivary gland inflammation J:88055
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(HLA-DRB1)31Dmz/0
Tg(Ins2-CD80)3B7Flv/0

(involves: 129S2/SvPas * C57BL/6 * CBA * SJL)
abnormal CD4-positive, alpha beta T cell morphology J:68641
abnormal CD8-positive, alpha beta T cell morphology J:68641
decreased susceptibility to autoimmune diabetes J:68641
salivary gland inflammation J:68641
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Tg(Ins2-CD80)3B7Flv/0

(involves: 129S2/SvPas * C57BL/6 * CBA)
decreased susceptibility to autoimmune diabetes J:68641
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
Themistm1Lov/Themistm1Lov

(involves: 129)
abnormal negative T cell selection J:151075
H2-Ab1b-tm1Koni/H2-Ab1b-tm1.1Koni
Tg(Tek-cre)12Flv/0

(involves: 129X1/SvJ * C3H * C57BL/6 * C57BL/6J)
abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology J:131774
abnormal T cell activation J:131774
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:131774
decreased level of surface class II molecules J:131774
immune system phenotype J:131774
increased CD4-positive, alpha-beta T cell number J:131774
H2-Ab1b-tm1Wug/H2-Ab1b-tm1Wug
(involves: C57BL/6)
abnormal B cell physiology J:204951
abnormal dendritic cell physiology J:204951
absent CD4-positive, alpha-beta T cells J:204951
decreased susceptibility to experimental autoimmune encephalomyelitis J:204951
H2-Ab1b-tm1Wug/H2-Ab1b-tm1Wug
Cd19tm1(cre)Cgn/Cd19+

(involves: 129S2/SvPas * C57BL/6)
abnormal B cell physiology J:204951
abnormal dendritic cell physiology J:204951
decreased susceptibility to experimental autoimmune encephalomyelitis J:204951
immune system phenotype J:204951
H2-Ab1bm12/H2-Ab1bm12
(B6(C)-H2-Ab1bm12/KhEgJ)
abnormal level of surface class II molecules J:100194
abnormal T cell physiology J:100123
decreased susceptibility to autoimmune disorder J:100123
decreased susceptibility to experimental autoimmune myasthenia gravis J:100213
decreased susceptibility to parasitic infection J:48242
H2-Ab1bm12/H2-Ab1bm12
(NZB.B6(C)-H2-Ab1bm12)
abnormal immunoglobulin level J:104189
abnormal level of surface class II molecules J:104189
autoimmune response J:4554
decreased CD8-positive, alpha-beta T cell number J:4554
increased anti-double stranded DNA antibody level J:104189
increased anti-erythrocyte antigen antibody level J:4554
increased anti-single stranded DNA antibody level J:104189
increased B cell number J:104189
increased CD4-positive, alpha-beta T cell number J:4554
increased double-negative T cell number J:4554
H2-Ab1g7-em1Dvs/H2-Ab1g7-em1Dvs
H2-D1b-em5Dvs/H2-D1b-em5Dvs
H2-K1d-em1Dvs/H2-K1d-em1Dvs

(NOD/ShiLtDvs-H2-K1d-em1Dvs H2-Ab1g7-em1Dvs H2-D1em5Dvs/Dvs)
abnormal T cell subpopulation ratio J:257229
decreased alpha-beta T cell number J:257229
decreased CD4-positive, alpha-beta T cell number J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-Ab1g7-em1Ygch/H2-Ab1g7-em1Ygch
(NOD/ShiLtJ-H2-Ab1g7-em1Ygch)
decreased CD4-positive, alpha-beta T cell number J:101977
H2-D1b-em1Dvs/H2-D1b-em1Dvs
(NOD/ShiLtDvs-H2-D1b-em1Dvs/Dvs)
abnormal immune system physiology J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-D1b-em2Dvs/H2-D1b-em2Dvs
(NOD/ShiLtDvs-H2-D1b-em2Dvs/Dvs)
abnormal immune system physiology J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-D1b-em3Dvs/H2-D1b-em3Dvs
(NOD/ShiLtDvs-H2-D1b-em3Dvs/Dvs)
abnormal immune system physiology J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-D1b-em4Dvs/H2-D1b-em4Dvs
(NOD/ShiLtDvs-H2-D1b-em4Dvs/Dvs)
abnormal immune system physiology J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-D1b-em5Dvs/H2-D1b-em5Dvs
H2-K1d-em1Dvs/H2-K1d-em1Dvs

(NOD/ShiLtDvs-H2-K1d-em1Dvs H2-D1b-em5Dvs/Dvs)
abnormal T cell subpopulation ratio J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-D1b-em5Dvs/H2-D1b-em5Dvs
H2-K1d-em1Dvs/H2-K1d-em1Dvs
Tg(HLA-A/H2-D/B2M)1Dvs/?

(NOD/ShiLtDvs-H2-K1d-em1Dvs H2-D1b-em5Dvs Tg(HLA-A/H2-D/B2M)1Dvs/Dvs)
autoimmune response J:257229
increased susceptibility to autoimmune diabetes J:257229
insulitis J:257229
H2-D1b-em5Dvs/H2-D1b-em5Dvs
H2-K1d-em1Dvs/H2-K1d-em1Dvs
Tg(HLA-B39/H2-D/B2m)2Dvs/?

(NOD/ShiLtDvs-H2-K1d-em1Dvs H2-D1b-em5Dvs Tg(HLA-B39/H2-D/B2M)2Dvs/Dvs)
autoimmune response J:257229
increased susceptibility to autoimmune diabetes J:257229
insulitis J:257229
H2-D1b-tm1Bpe/H2-D1b-tm1Bpe
H2-K1b-tm1Bpe/H2-K1b-tm1Bpe

(involves: 129P2/OlaHsd * C57BL/6)
absent CD8-positive, alpha-beta T cells J:57703
decreased CD8-positive, alpha-beta T cell number J:54709
decreased susceptibility to Riboviria infection induced morbidity/mortality J:54709
increased CD4-positive, alpha-beta T cell number J:54709
H2-D1b-tm1Bpe/H2-D1b-tm1Bpe
H2-K1b-tm1Bpe/H2-K1b-tm1Bpe

(B6.129P-H2-D1b-tm1Bpe H2-K1b-tm1Bpe)
abnormal cytotoxic T cell physiology J:118960
H2-D1b-tm1Bpe/H2-D1b-tm1Bpe
H2-K1b-tm1Bpe/H2-K1b-tm1Bpe
Klra1tm1.1Wyok/Klra1tm1.1Wyok
Tg(H2-Dd)28Bee/0

(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6NTac * DBA/2)
abnormal NK cell physiology J:252851
H2-D1b-tm1Bpe/H2-D1b-tm1Bpe
H2-K1b-tm1Bpe/H2-K1b-tm1Bpe
X/Yaa

(BXSB.129P2(B6)-H2-K1b-tm1Bpe H2-D1b-tm1Bpe/Dcr)
increased susceptibility to systemic lupus erythematosus J:179430
H2-D1bm14/H2-D1bm14
(C57BL/6)
abnormal T cell activation J:97717
spinal cord inflammation J:97717
H2-DMatm1Doi/H2-DMatm1Doi
(involves: 129S2/SvPas * C57BL/6)
abnormal professional antigen presenting cell physiology J:31624
immune system phenotype J:31624
H2-DMatm1Liz/H2-DMatm1Liz
(involves: BALB/cJ)
abnormal antigen presentation via MHC class II J:113714
abnormal CD4-positive, alpha beta T cell morphology J:113714
abnormal professional antigen presenting cell physiology J:111565, J:113714
defective assembly of class II molecules J:113714
H2-DMatm1Lkrl/H2-DMatm1Lkrl
(involves: 129P2/OlaHsd)
abnormal antigen presentation J:31786
abnormal CD4-positive, alpha-beta T cell physiology J:31786
abnormal positive T cell selection J:31786
abnormal professional antigen presenting cell physiology J:31786
decreased CD4-positive, alpha-beta T cell number J:31786
H2-DMatm1Luc/H2-DMatm1Luc
(involves: 129S4/SvJae)
abnormal antigen presentation via MHC class II J:31625
abnormal CD4-positive, alpha-beta T cell physiology J:31625
abnormal level of surface class II molecules J:45185
abnormal positive T cell selection J:125548
decreased CD4-positive, alpha-beta T cell number J:31625, J:45185
decreased interferon-gamma secretion J:45185
increased susceptibility to bacterial infection J:45185
H2-DMatm1Luc/H2-DMatm1Luc
(involves: 129S4/SvJae * C57BL/6)
abnormal antigen presentation J:72243
decreased susceptibility to experimental autoimmune encephalomyelitis J:72243
H2-DMatm1Luc/H2-DMatm1Luc
(B6.129S4-H2-Dmatm1Luc)
abnormal antigen presentation J:125654
abnormal T-helper 1 physiology J:125654
decreased susceptibility to experimental autoimmune encephalomyelitis J:125654
decreased susceptibility to type IV hypersensitivity reaction J:125654
H2-DMatm1Luc/H2-DMatm1Luc
Cd74tm1Doi/Cd74tm1Doi

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6)
abnormal level of surface class II molecules J:45185
increased susceptibility to parasitic infection J:45185
H2-DMatm2Liz/H2-DMatm2Liz
(involves: C57BL/6 * C57BL/10 * C57BR * CBA)
abnormal antigen presentation via MHC class II J:111565
abnormal professional antigen presenting cell physiology J:111565
decreased T cell proliferation J:111565
H2-K1b-tm1Bpe/H2-K1b-tm1Bpe
(involves: 129P2/OlaHsd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:54709
increased CD4-positive, alpha-beta T cell number J:54709
H2-K1d-em4Dvs/H2-K1d-em4Dvs
(NOD/ShiLtDvs-H2-K1d-em4Dvs/Dvs)
abnormal immune system physiology J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-K1d-em5Dvs/H2-K1d-em5Dvs
(NOD/ShiLtDvs-H2-K1d-em5Dvs/Dvs)
abnormal immune system physiology J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-K1d-em7Dvs/H2-K1d-em7Dvs
(NOD/ShiLtDvs-H2-K1d-em7Dvs/Dvs)
abnormal immune system physiology J:257229
decreased susceptibility to autoimmune diabetes J:257229
H2-Kbm1/H2-Kbm1
Tg(TcraTcrb)1100Mjb/?

(involves: C57BL/6)
abnormal positive T cell selection J:92867
H2-Kbm5/H2-Kbm5
Tg(TcraTcrb)1100Mjb/?

(involves: C57BL/6)
abnormal positive T cell selection J:133645
H2-Kdm4/H2-Kdm4
(involves: BALB/cKh * C57BL/6Kh)
immune system phenotype J:109272
H2-Kdm5/H2-Kdm5
(involves: BALB/cKh * C57BL/6Kh)
immune system phenotype J:109272
H2-M3tm1Crw/H2-M3tm1Crw
(B6.129-H2-M3tm1Crw)
abnormal CD8-positive, alpha beta T cell morphology J:118960
abnormal cytotoxic T cell physiology J:118960
abnormal innate immunity J:118960
decreased activated T cell number J:118960
decreased interferon-gamma secretion J:118960
decreased macrophage nitric oxide production J:118960
impaired natural killer cell mediated cytotoxicity J:118960
increased susceptibility to bacterial infection J:118960
H2-Oatm1Dma/H2-Oatm1Dma
(involves: 129/Sv * C57BL/6)
abnormal antigen presentation via MHC class II J:65235
increased CD4-positive, alpha-beta T cell number J:65235
H2-Oatm1Lkar/H2-Oatm1Lkar
(involves: 129P2/OlaHsd)
abnormal antigen presentation via MHC class II J:85084
immune system phenotype J:85084
increased IgG1 level J:85084
H2-Obem1Tvg/H2-Obem1Tvg
(C57BL/6J-H2-Obem1Tvg/Tvg)
decreased susceptibility to Retroviridae infection J:254532
defective assembly of class II molecules J:254532
immune system phenotype J:254532
H2-Obvic1/H2-Obvic1
(I/LnJ)
decreased susceptibility to Retroviridae infection J:163153
decreased susceptibility to viral infection J:81554, J:60602
H2-Obvic1/H2-Obvic1
(C3N.I-H2-Obvic1)
decreased susceptibility to Retroviridae infection J:254532
H2-Obvic1/H2-Obvic1
(B6.I-H2-Obvic1)
decreased susceptibility to Retroviridae infection J:254532
H2-Obvic1/H2-Obvic1
(C.I-H2-Obvic1)
decreased susceptibility to Retroviridae infection J:254532
H2-Q10tm1.1(KOMP)Mbp/H2-Q10tm1.1(KOMP)Mbp
(involves: C57BL/6 * C57BL/6N)
decreased gamma-delta T cell number J:294888
decreased immature NK cell number J:294888
decreased mature NK cell number J:294888
decreased NK cell number J:294888
increased NK cell number J:294888
H2-T18b/H2-T18b
H2-T3tm1Luc/H2-T3tm1Luc

(C57BL/6-H2-T3tm1Luc)
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:142515
abnormal CD8-positive, gamma-delta intraepithelial T cell morphology J:142515
abnormal intraepithelial T cell morphology J:142515
increased interferon-gamma secretion J:142515
H2-T18b/H2-T18b
H2-T3tm1Luc/H2-T3tm1Luc
Tcratm1Mom/Tcratm1Mom

(B6.Cg-Tcratm1Mom H2-T3tm1Luc)
abnormal intraepithelial T cell number J:142515
colitis J:142515
enlarged mesenteric lymph nodes J:142515
increased interleukin-4 secretion J:142515
H2-T23tm1Cant/H2-T23tm1Cant
(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:142087, J:123555
abnormal memory T cell physiology J:123555
increased susceptibility to bacterial infection J:89808
increased susceptibility to experimental autoimmune encephalomyelitis J:89808
increased susceptibility to Herpesvirales infection J:89808
H2-T23tm2Cant/H2-T23tm2Cant
(involves: 129S6/SvEvTac)
abnormal CD4-positive, alpha-beta T cell physiology J:123555
H2-T23tm2Cant/H2-T23tm2Cant
(B6.129S6-H2-T23tm2Cant)
abnormal CD4-positive, alpha-beta T cell physiology J:142087
decreased susceptibility to experimental autoimmune encephalomyelitis J:142087
H2-T23tm2Cant/H2-T23tm2Cant
Tg(Tcra2D2,Tcrb2D2)1Kuch/?

(involves: 129S6/SvEvTac)
abnormal CD4-positive, alpha-beta T cell physiology J:142087
increased susceptibility to experimental autoimmune encephalomyelitis J:142087
H2-T23tm3Cant/H2-T23tm3Cant
(B6.129S6-H2-T23tm3Cant)
increased susceptibility to experimental autoimmune encephalomyelitis J:142087
H2-T23tm3Cant/H2-T23tm3Cant
Tg(Tcra2D2,Tcrb2D2)1Kuch/?

(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:142087
H2-T23tm3Cant/H2-T23tm3Cant
Tg(TcraTcrb)425Cbn/?

(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:142087
H2-T24em1(IMPC)Wtsi/H2-T24em1(IMPC)Wtsi
(C57BL/6N-H2-T24em1(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
H2b/H2b
(NOD.B10SnJ-H2b)
decreased susceptibility to autoimmune diabetes J:14178
periinsulitis J:14178
H2b/H2b
Itktm1Ljb/Itktm1Ljb
Tg(TcrAND)53Hed/?

(involves: C3H/HeJ * C57BL/6 * C57BL/10)
abnormal positive T cell selection J:123795
decreased CD4-positive, alpha-beta T cell number J:123795
H2b/H2b
Nfkbidtm1Clay/Nfkbidtm1Clay
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?

(involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6)
abnormal thymocyte activation J:132071
decreased interleukin-2 secretion J:132071
decreased T cell proliferation J:132071
H2b/H2b
Ptcratm1Vbo/Ptcratm1Vbo

(involves: 129P2/OlaHsd)
decreased double-positive T cell number J:131357
decreased thymocyte number J:131357
spleen hypoplasia J:131357
H2b/H2b
Ptcratm1Vbo/Ptcratm1Vbo
Tcratm1Mom/Tcra/Tcrdtm1.1(Tcra)Rsky
Tg(Tcrb)93Vbo/?

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal T cell differentiation J:131357
decreased thymocyte number J:131357
H2b/H2b
Ptcratm1Vbo/Ptcratm1Vbo
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal T cell differentiation J:131357
H2b/H2b
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra19,Tcrb19)#Stl/0

(involves: 129S7/SvEvBrd * C57BL/6)
immune system phenotype J:19795
H2b/H2b
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?

(involves: 129S/SvEv * C57BL/6)
abnormal cytotoxic T cell physiology J:133112
arrested T cell differentiation J:133112
decreased CD4-positive, alpha-beta T cell number J:133112
increased CD8-positive, alpha-beta T cell number J:133112
increased T cell proliferation J:133112
H2b/H2b
Tcra/Tcrdtm1.1(Tcra)Rsky/Tcra/Tcrdtm1.1(Tcra)Rsky
Tg(Tcrb)93Vbo/?

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal negative T cell selection J:81564
abnormal T cell differentiation J:81564
H2b/H2b
Tcra/Tcrdtm1.1(Tcra)Rsky/Tcra/Tcrdtm1.1(Tcra)Rsky
Tg(Tcrb)93Vbo/?

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal negative T cell selection J:81564
abnormal T cell differentiation J:81564
H2b/H2b
Tcratm1Mom/Tcra/Tcrdtm1.1(Tcra)Rsky
Tg(Tcrb)93Vbo/?

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal double-negative T cell morphology J:131357
abnormal double-positive T cell morphology J:81564
abnormal negative T cell selection J:81564
abnormal T cell differentiation J:81564
decreased double-positive T cell number J:131357
decreased thymocyte number J:131357
H2b/H2d
((C57BL/6 x DBA/2)F1)
abnormal cytokine secretion J:106141
abnormal T cell differentiation J:106141
decreased susceptibility to parasitic infection J:106141
increased autoantibody level J:106141
H2b/H2d
Tg(Ins2-E3)1Dvs/0

(involves: BALB/c * C57BL/6 * DBA/2J)
increased length of allograft survival J:109763
H2b/H2d
Tg(TcraTcrb)1100Mjb/?

(involves: BALB/c * C57BL/6)
abnormal negative T cell selection J:133645
decreased CD8-positive, alpha-beta T cell number J:133645
small thymus J:133645
H2b/H2d
Themistm1Gasc/Themistm1Gasc

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * DBA/2)
abnormal negative T cell selection J:151074
H2b/H2g7
(NOD.B10SnJ-H2b)
decreased susceptibility to autoimmune diabetes J:14178
H2b/H2g7
Tg(TcraR28,TcrbR28)KRNDim/0

(involves: C57BL/6 * NOD * SJL)
mitral valve inflammation J:275827
rheumatoid arthritis J:36815, J:275827
H2b/H2k
Itktm1Ljb/Itktm1Ljb
Tg(TcrAND)53Hed/?

(involves: C3H/HeJ * C57BL/6 * C57BL/10)
abnormal positive T cell selection J:123795
decreased CD4-positive, alpha-beta T cell number J:123795
H2b/H2k
Tg(TcraTcrb)1100Mjb/?

(involves: C57BL/6 * C57BL/10Sg * C57BR/c)
abnormal negative T cell selection J:133645
decreased CD8-positive, alpha-beta T cell number J:133645
small thymus J:133645
H2b/H2s
Tg(TcraTcrb)1100Mjb/?

(involves: A/WySn * C57BL/6 * C57BL/10Sg * Swiss)
abnormal negative T cell selection J:133645
decreased CD8-positive, alpha-beta T cell number J:133645
small thymus J:133645
H2d/H2d
(DBA/2)
abnormal cytokine secretion J:106141
abnormal T cell differentiation J:106141
decreased susceptibility to parasitic infection J:106141
increased autoantibody level J:106141
H2d/H2d
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraN15,TcrbN15)L2Elre/?

(involves: 129S/SvEv * C57BL/6)
arrested T cell differentiation J:133112
decreased CD4-positive, alpha-beta T cell number J:133112
decreased CD8-positive, alpha-beta T cell number J:133112
H2d/H2d
Tcra/Tcrdtm1.1(Tcra)Rsky/Tcra/Tcrdtm1.1(Tcra)Rsky
Tg(Tcrb)93Vbo/0

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal T cell differentiation J:131357
decreased thymocyte number J:131357
H2d/H2d
Tg(TcraP1.5,TcrbP1.5)29Amsv/0
Trap1atm1.1Jvde/Y

(involves: 129 * BALB/cJ * C57BL/10 * DBA/2)
abnormal T cell clonal deletion J:180807
H2d/H2d
Trap1atm1.1Jvde/Y

(involves: 129 * BALB/cJ * C57BL/10 * DBA/2)
abnormal CD8-positive, alpha-beta T cell physiology J:180807
abnormal immune tolerance J:180807
H2dlAb1-Ea/H2dlAb1-Ea
(B6.129S2-H2dlAb1-Ea/J)
increased susceptibility to bacterial infection J:123934
H2dlAb1-Ea/H2dlAb1-Ea
(involves: 129S2/SvPas * C57BL/6)
abnormal immunoglobulin level J:57484
abnormal T cell number J:57484
decreased CD4-positive, alpha-beta T cell number J:57484
decreased IgG1 level J:57484
decreased IgG2a level J:57484
immune system phenotype J:157516
increased CD8-positive, alpha-beta T cell number J:57484
increased IgM level J:57484
H2dlAb1-Ea/H2dlAb1-Ea
Marchf1tm1.1Sish/Marchf1tm1.1Sish

(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6)
immune system phenotype J:157516
H2dlAb1-Ea/H2dlAb1-Ea
Psmb11tm1(Psmb8)Khog/Psmb11tm1(Psmb8)Khog

(involves: 129S2/SvPas * C57BL/6)
abnormal T cell differentiation J:196156
decreased CD8-positive, alpha-beta T cell number J:196156
H2dlAb1-Ea/H2dlAb1-Ea
Rag1tm1Mom/Rag1tm1Mom
Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0
Tg(TRATL3A6,TRBTL3A6)#Kito/0

(involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6)
brain inflammation J:189816
H2dlAb1-Ea/H2dlAb1-Ea
Rag1tm1Mom/Rag1tm1Mom
Tg(HLA-DRA,HLA-DRB5*0101)loKito/0
Tg(TRATL3A6,TRBTL3A6)#Kito/0

(involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6)
brain inflammation J:189816
H2dlAb1-Ea/H2dlAb1-Ea
Rr381em2Kap/Rr381em2Kap

(involves: 129S2/SvPas * C57BL/6)
absent CD4-positive, alpha-beta T cells J:333471
H2dlAb1-Ea/H2dlAb1-Ea
Rr381em4Kap/Rr381em4Kap

(involves: 129S2/SvPas * C57BL/6)
absent CD8-positive, alpha-beta T cells J:333471
H2dlAb1-Ea/H2dlAb1-Ea
Rr381em5Kap/Rr381em5Kap

(involves: 129S2/SvPas * C57BL/6)
absent CD8-positive, alpha-beta T cells J:333471
H2dlAb1-Ea/H2dlAb1-Ea
Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0
Tg(TRATL3A6,TRBTL3A6)#Kito/0

(involves: 129S2/SvPas * C57BL/6)
abnormal cytokine secretion J:189816
brain inflammation J:189816
CNS inflammation J:189816
increased CD4-positive, alpha-beta T cell number J:189816
increased inflammatory response J:189816
increased interferon-gamma secretion J:189816
increased interleukin-17 secretion J:189816
increased susceptibility to experimental autoimmune encephalomyelitis J:189816
increased T-helper 1 cell number J:189816
increased T-helper 17 cell number J:189816
H2dlAb1-Ea/H2dlAb1-Ea
Tg(HLA-DRA,HLA-DRB5*0101)loKito/0
Tg(TRATL3A6,TRBTL3A6)#Kito/0

(involves: 129S2/SvPas * C57BL/6)
brain inflammation J:189816
increased susceptibility to experimental autoimmune encephalomyelitis J:189816
H2g7/H2g7
Ins2tm1Jja/Ins2tm1Jja
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0

(involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 * FVB * NOD)
increased susceptibility to autoimmune diabetes J:111874
H2g7/H2g7
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0

(involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD)
increased susceptibility to autoimmune diabetes J:111874
insulitis J:111874
H2g7/H2g7
Tg(Ins2-Vtcn1)#Xxz/0
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(involves: C57BL/6 * NOD * SJL)
decreased interferon-gamma secretion J:177612
decreased interleukin-17 secretion J:177612
decreased regulatory T cell number J:177612
decreased susceptibility to autoimmune diabetes J:177612
H2g7/H2g7
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0

(B6.NOD-(D17Mit21-D17Mit10) Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs)
increased susceptibility to autoimmune diabetes J:167508
H2g7/H2g7
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(B6.Cg-H2g7 Tg(TcraBDC2.5,TcrbBDC2.5)1Doi)
decreased susceptibility to autoimmune diabetes J:86926
H2g7/H2g7
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0

(involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD)
decreased susceptibility to autoimmune diabetes J:111874
insulitis J:111874
H2g7/H2q
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0

(involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD)
increased susceptibility to autoimmune diabetes J:111874
H2h2/H2g7
(NOD.Cg-H2h2)
decreased susceptibility to autoimmune diabetes J:14178
H2h2/H2h2
(NOD.Cg-H2h2)
decreased susceptibility to autoimmune diabetes J:14178
insulitis J:14178
periinsulitis J:14178
H2h4/H2g7
(NOD.Cg-H2h4)
decreased susceptibility to autoimmune diabetes J:14178
H2h4/H2h4
(NOD.Cg-H2h4)
abnormal cytokine secretion J:54563
decreased susceptibility to autoimmune diabetes J:14178
insulitis J:14178
periinsulitis J:14178
thyroid gland inflammation J:54563
H2i5/H2g7
(NOD.Cg-H2i5)
decreased susceptibility to autoimmune diabetes J:14178
H2i5/H2i5
(NOD.Cg-H2i5)
decreased susceptibility to autoimmune diabetes J:14178
periinsulitis J:14178
H2i7/H2g7
(NOD.Cg-H2i7)
decreased susceptibility to autoimmune diabetes J:14178
H2i7/H2g7
((NOD x NOD.Cg-H2i7)F1)
insulitis J:14178
H2i7/H2i7
(NOD.Cg-H2i7)
decreased susceptibility to autoimmune diabetes J:14178
periinsulitis J:14178
H2k/H2g7
(NOD.Cg-H2k)
decreased susceptibility to autoimmune diabetes J:14178
H2k/H2k
(NOD.Cg-H2k)
increased susceptibility to autoimmune diabetes J:14178
periinsulitis J:14178
H2k/H2k
Tg(TcraTcrbAD10)1Hed/?

(involves: C57BL/6 * SJL)
increased CD4-positive, alpha-beta T cell number J:124701
H2q/?
Ncf1m1J/Ncf1m1J

(B6.Cg-Ncf1m1J H2q)
decreased susceptibility to experimental autoimmune encephalomyelitis J:92437
increased susceptibility to experimental autoimmune encephalomyelitis J:92437
increased susceptibility to induced arthritis J:92437
increased susceptibility to type IV hypersensitivity reaction J:92437
rheumatoid arthritis J:92437
H2q/H2q
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0

(involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD)
decreased susceptibility to autoimmune diabetes J:111874
H2u/H2u
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra19,Tcrb19)#Stl/0

(either: (involves: 129S7/SvEvBrd * C57BL/6 * PL/J) or (involves: 129S7/SvEvBrd * C57BL/6 * C57BL/10 * PL/J))
increased susceptibility to autoimmune disorder J:19795
H2u/H2u
Tg(Tcra19,Tcrb19)#Stl/0

(either: (involves: C57BL/6 * PL/J) or (involves: C57BL/6 * C57BL/10 * PL/J))
increased susceptibility to autoimmune disorder J:19795
increased susceptibility to experimental autoimmune encephalomyelitis J:19795
H2u/H2u
Tg(TCRA)B1Jg/0

(B10.PL-H2u H2-T18a/(73NS)Sn-Tg(TCRA)B1Jg/J)
abnormal thymus cell ratio J:92992
decreased CD4-positive, alpha-beta T cell number J:92992
decreased double-positive T cell number J:92992
decreased thymocyte number J:92992
increased double-negative T cell number J:92992
H2u/H2u
Tg(TCRA)B1Jg/?
Tg(TCRB)C14Jg/?

(involves: C57BL/6 * C57BL/10SnSg * DBA/2 * PL/J)
abnormal CD4-positive, alpha-beta T cell physiology J:92991
abnormal effector T cell morphology J:92991
decreased CD8-positive, alpha-beta T cell number J:92991
decreased double-positive T cell number J:92991
increased autoantibody level J:92991
increased CD4-positive, alpha-beta T cell number J:92991
increased susceptibility to experimental autoimmune encephalomyelitis J:92991
H2u/H2u
Tg(TCRA)B1Jg/0
Tg(TCRB)C14Jg/0

(B10.PL-H2u H2-T18a/(73NS)Sn-Tg(TCRA)B1Jg Tg(TCRB)C14Jg)
abnormal double-negative T cell morphology J:92992
abnormal double-positive T cell morphology J:92992
abnormal thymus cell ratio J:92992
absent gamma-delta T cells J:92992
decreased double-positive T cell number J:92992
increased CD4-positive, alpha-beta T cell number J:92992
increased double-negative T cell number J:92992
H2u/H2u
Tg(TCRB)C14Jg/0

(B10.PL-H2u H2-T18a/(73NS)Sn-Tg(TCRB)C14Jg/J)
abnormal double-negative T cell morphology J:92992
abnormal double-positive T cell morphology J:92992
absent gamma-delta T cells J:92992
H2axtm1Fwa/H2axtm1Fwa
(involves: 129S6/SvEvTac)
abnormal class switch recombination J:84879
decreased lymphocyte cell number J:84879
H2axtm1Nus/H2axtm1Nus
(Not Specified)
abnormal class switch recombination J:194603, J:120658
decreased B cell number J:76360
decreased IgG level J:73342
decreased T cell number J:76360
H2axtm1Nus/H2axtm1Nus
Ightm1Mnz/Ightm1Mnz

(involves: 129P2/OlaHsd)
immune system phenotype J:120658
H2axtm1Nus/H2axtm1Nus
Ightm2Mnz/Ightm2Mnz

(involves: 129P2/OlaHsd)
immune system phenotype J:120658
H2bc4em1(IMPC)Tcp/H2bc4em1(IMPC)Tcp
(C57BL/6N-H2bc4em1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
H13tm1b(KOMP)Wtsi/H13tm1b(KOMP)Wtsi
(C57BL/6N-H13tm1b(KOMP)Wtsi/Wtsi)
abnormal thymus topology J:239583
blood in lymph vessels J:239583
Habp2tm1Lex/Habp2tm1Lex
(involves: 129S7/SvEvBrd * BALB/c * C57BL/6)
liver inflammation J:207454
Hacd3em1(IMPC)Mbp/Hacd3em1(IMPC)Mbp
(C57BL/6N-Hacd3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Hamptm1Svl/Hamptm1Svl
(involves: 129S2/SvPas * C57BL/6)
decreased spleen iron level J:119004
Hamptm1Svl/Hamptm1Svl
(involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6)
increased susceptibility to bacterial infection induced morbidity/mortality J:199427
Hand2tm1Cse/Hand2+
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129S1/Sv * C57BL/6J * CBA/J)
abnormal thymus development J:155265
Has1tm1b(KOMP)Wtsi/Has1tm1b(KOMP)Wtsi
(C57BL/6N-Has1tm1b(KOMP)Wtsi/H)
decreased eosinophil cell number J:211773
increased basophil cell number J:211773
Havcr1tm1Kuch/Havcr1tm1Kuch
(B6.Cg-Havcr1tm1Kuch)
abnormal B cell physiology J:186484
abnormal CD4-positive, alpha-beta T cell physiology J:186484
abnormal dendritic cell physiology J:186484
abnormal T cell differentiation J:186484
autoimmune response J:186484
enlarged spleen J:186484
increased activated T cell number J:186484
increased anti-double stranded DNA antibody level J:186484
increased CD4-positive, alpha-beta T cell number J:186484
increased CD8-positive, alpha-beta T cell number J:186484
increased double-negative T cell number J:186484
increased T cell number J:186484
Havcr1tm1Shw/Havcr1tm1Shw
(C.129P2-Havcr1tm1Shw)
immune system phenotype J:166400
Havcr1tm1Vlcg/Havcr1tm1Vlcg
(B6.129-Havcr1tm1Vlcg)
immune system phenotype J:187793
increased interleukin-5 secretion J:187793
increased interleukin-13 secretion J:187793
Havcr1tm1Vlcg/Havcr1tm1Vlcg
(C.129-Havcr1tm1Vlcg)
abnormal cytokine secretion J:187793
immune system phenotype J:187793
increased interleukin-4 secretion J:187793
increased interleukin-5 secretion J:187793
increased interleukin-10 secretion J:187793
increased interleukin-13 secretion J:187793
increased interleukin-17 secretion J:187793
respiratory system inflammation J:187793
Havcr2tm1b(KOMP)Wtsi/Havcr2tm1b(KOMP)Wtsi
(C57BL/6N-Havcr2tm1b(KOMP)Wtsi/Ucd)
increased spleen weight J:211773
Havcr2tm1Bmed/Havcr2tm1Bmed
(B6.Cg-Havcr2tm1Bmed)
abnormal CD8-positive, alpha-beta T cell physiology J:189839
decreased activation-induced cell death of T cells J:189839
decreased interferon-gamma secretion J:189839
decreased susceptibility to Orthomyxoviridae infection J:189839
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:189839
decreased T cell proliferation J:189839
Havcr2tm1Tbs/Havcr2tm1Tbs
(C.Cg-Havcr2tm1Tbs)
immune system phenotype J:86260
Havcr2tm1Vlcg/Havcr2tm1Vlcg
(B6.129-Havcr2tm1Vlcg)
decreased interferon-gamma secretion J:209885
decreased T cell number J:209885
Havcr2tm1Vlcg/Havcr2tm1Vlcg
Tg(TcraTcrb)1100Mjb/?

(B6.Cg-Havcr2tm1Vlcg Tg(TcraTcrb)1100Mjb)
decreased interferon-gamma secretion J:209885
decreased T cell number J:209885
Hax1tm1.1Gach/Hax1tm1.1Gach
(involves: BALB/c)
abnormal B cell number J:174159
abnormal lymphocyte morphology J:174159
abnormal T cell number J:174159
decreased B cell number J:174159
decreased B-1a cell number J:174159
decreased CD4-positive, alpha-beta T cell number J:174159
decreased CD8-positive, alpha-beta T cell number J:174159
decreased double-positive T cell number J:174159
decreased IgG2a level J:174159
decreased immature B cell number J:174159
decreased marginal zone B cell number J:174159
decreased mature B cell number J:174159
decreased pre-B cell number J:174159
decreased pro-B cell number J:174159
decreased thymocyte number J:174159
decreased transitional stage T1 B cell number J:174159
decreased transitional stage T2 B cell number J:174159
increased follicular B cell number J:174159
spleen hypoplasia J:174159
thymus hypoplasia J:174159
Hax1tm1Jni/Hax1tm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
decreased double-positive T cell number J:132627
decreased immature B cell number J:132627
decreased leukocyte cell number J:132627
decreased lymphocyte cell number J:132627
decreased neutrophil cell number J:132627
decreased single-positive T cell number J:132627
decreased T cell number J:132627
Hbab2(th)/Hba+
(either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC))
increased leukocyte cell number J:123943
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow

(Not Specified)
abnormal Kupffer cell morphology J:134980
abnormal spleen white pulp morphology J:134980
enlarged spleen J:134980
increased spleen red pulp amount J:134980
spleen vascular congestion J:134980
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow
Slc12a4Rbc10/Slc12a4+

(involves: 129 * BALB/c * C57BL/6J)
enlarged spleen J:227339
liver inflammation J:227339
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm2(HBG1,HBD,HBB*)Ryan

(Not Specified)
intermingled spleen red and white pulp J:148521
spleen hyperplasia J:148521
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm3(HBG1,HBB)Tow

(Not Specified)
spleen hyperplasia J:148521
Hbatm1Paz/Hbatm1Paz
Hbbtm1Tow/Hbbtm1Tow
Tg(HBA-HBBs)41Paz/?

(involves: 129S2/SvPas * 129S7/SvEvBrd * Black Swiss * C57BL/6 * DBA/2* FVB/N)
increased spleen weight J:44161
spleen vascular congestion J:44161
Hbb-b1MommeD7/Hbb-b1+
(involves: FVB/N)
enlarged spleen J:142335, J:190446
increased spleen red pulp amount J:190446
Hbb-b1Rbc13/Hbb-b1+
(involves: BALB/c * C57BL/6)
enlarged spleen J:190446
increased spleen red pulp amount J:190446
Hbb-b1tm1Shs/Hbb-b1tm1Shs
(involves: C57BL/6)
enlarged spleen J:78271
increased spleen iron level J:78271
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal spleen morphology J:88672, J:30155
decreased spleen white pulp amount J:30155
increased spleen weight J:30155
intermingled spleen red and white pulp J:30155
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+

(involves: 129P2/OlaHsd * C57BL/6N)
enlarged spleen J:185154
increased spleen iron level J:185154
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+

(B6;129-Hbb-b1tm1Unc Hbb-b2tm1Unc/J)
abnormal spleen morphology J:211331
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+

(involves: 129P2/OlaHsd)
enlarged spleen J:97548
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tg(HBB*)L2Pai/0

(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:97548
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tmprss6tm1Otin/Tmprss6+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N)
abnormal spleen iron level J:185154
abnormal spleen size J:185154
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tmprss6tm1Otin/Tmprss6tm1Otin

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N)
abnormal spleen size J:185154
Hbbd3th/Hbb+
Tg(LCR-HBA1,LCR-HBB*)1Tow/0

(involves: C57BL/6 * DBA/2J * SJL)
enlarged spleen J:127701
Hbbd3th/Hbb+
Tg(LCR-HBA2,LCR-HBB*)1Cos/0

(involves: C57BL/6J * CBA/J * DBA/2J)
enlarged spleen J:94193
Hbbd3th/Hbbd3th
Tg(HBB-AR-HBA2,-HBB*)58Rub/0
Tg(LCR-HBA2,LCR-HBB)11Cos/0

(involves: FVB/N * Swiss Webster)
abnormal spleen morphology J:94190
enlarged spleen J:94190
increased spleen red pulp amount J:94190
spleen fibrosis J:94190
spleen vascular congestion J:94190
Hbbd4/Hbbd4
(involves: 101/H)
abnormal macrophage morphology J:7972
enlarged spleen J:7972
increased spleen red pulp amount J:7972
Hbbtm1.1(HBG1,HBB*)Ryan/Hbb+
(involves: C57BL/6J)
abnormal spleen morphology J:147906
enlarged spleen J:147906
increased spleen iron level J:147906
increased spleen red pulp amount J:147906
intermingled spleen red and white pulp J:147906
Hbbtm1Tow/Hbb+
(involves: 129S2/SvPas * C57BL/6)
enlarged spleen J:29087
increased spleen weight J:29087
Hbbtm2Unc/Hbb+
(involves: 129P2/OlaHsd * C57BL/6J)
enlarged spleen J:64295
increased spleen iron level J:64295
Hbnr1CBA/Hbnr1SWR
(involves: CBA * SWR)
decreased susceptibility to parasitic infection J:82261, J:85787
Hbnr1SWR/Hbnr1SWR
(involves: CBA * SWR)
decreased susceptibility to parasitic infection J:82261, J:110034, J:85787
Hbnr2CBA/Hbnr2SWR
(involves: CBA * SWR)
granulomatous inflammation J:85787
Hbnr2SWR/?
(involves: CBA * SWR)
decreased susceptibility to parasitic infection J:82261
Hbnr2SWR/Hbnr2SWR
(involves: CBA * SWR)
decreased IgE level J:85787
decreased susceptibility to parasitic infection J:110034
granulomatous inflammation J:85787
Hbnr3CBA/Hbnr3SWR
(involves: CBA * SWR)
decreased susceptibility to parasitic infection J:85787
increased susceptibility to parasitic infection J:82261
Hbnr3SWR/Hbnr3SWR
(involves: CBA * SWR)
increased susceptibility to parasitic infection J:82261, J:85787
Hbnr4SWR/Hbnr4SWR
(involves: CBA * SWR)
abnormal immune serum protein physiology J:85787
Hbnr5CBA/Hbnr5SWR
(involves: CBA * SWR)
decreased susceptibility to parasitic infection J:85787
Hbnr5SWR/Hbnr5SWR
(involves: CBA * SWR)
decreased susceptibility to parasitic infection J:85787
Hbnr6SWR/Hbnr6SWR
(involves: CBA * SWR)
increased IgE level J:85787
Hbnr7CBA/Hbnr7SWR
(involves: CBA * SWR)
decreased IgG1 level J:85787
Hbnr7SWR/Hbnr7SWR
(involves: CBA * SWR)
decreased IgG2b level J:85787
Hbnr8CBA/Hbnr8SWR
(involves: CBA * SWR)
decreased susceptibility to parasitic infection J:85787
Hbnr8SWR/Hbnr8SWR
(involves: CBA * SWR)
decreased susceptibility to parasitic infection J:85787
Hbs1ltm1a(KOMP)Wtsi/Hbs1ltm1a(KOMP)Wtsi
(C57BL/6N-Hbs1ltm1a(KOMP)Wtsi/Wtsi)
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased Langerhans cell number J:211773
decreased mature B cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
decreased monocyte cell number J:211773
decreased T-helper cell number J:211773
increased CD4-positive, alpha-beta memory T cell number J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased CD5-positive gamma-delta T cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased leukocyte cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased regulatory T cell number J:211773
Hc0/Hc0
(involves: C57BL/10SnJ)
increased susceptibility to bacterial infection J:44240
Hc0/Hc0
Tg(TcrbBL17)1Lmor/0

(involves: DBA/1J * SWR/J)
decreased susceptibility to induced arthritis J:134111
Hc1/?
Tg(TcrbBL17)1Lmor/0

(involves: DBA/1J * SWR/J)
increased susceptibility to induced arthritis J:134111
Hcar1em1(IMPC)Ccpcz/Hcar1em1(IMPC)Ccpcz
(C57BL/6N-Hcar1em1(IMPC)Ccpcz/Ccpcz)
decreased effector memory T-helper cell number J:211773
Hcfc2em1Btlr/Hcfc2em1Btlr
(C57BL/6J-Hcfc2em1Btlr)
decreased tumor necrosis factor secretion J:251008
Hcfc2fkls/Hcfc2+
(involves: C57BL/6J)
decreased interferon-beta secretion J:251008
decreased tumor necrosis factor secretion J:251008
Hcfc2fkls/Hcfc2fkls
(C57BL/6J-Hcfc2fkls)
abnormal innate immunity J:94077
Hcfc2fkls/Hcfc2fkls
(involves: C57BL/6J)
decreased circulating interferon-alpha level J:251008
decreased circulating interferon-beta level J:251008
decreased interferon-beta secretion J:251008
decreased tumor necrosis factor secretion J:251008
increased susceptibility to Herpesvirales infection J:251008
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:251008
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:251008
Hcfc2fkls/Hcfc2min
(involves: C57BL/6J)
decreased tumor necrosis factor secretion J:251008
Hcfc2fkls/Hcfc2sca
(involves: C57BL/6J)
decreased tumor necrosis factor secretion J:251008
Hcktm1Ern/Hcktm1Ern
(involves: 129S1/Sv * C57BL/6)
abnormal alveolar macrophage morphology J:111432
abnormal immune system physiology J:111432
abnormal macrophage physiology J:111432
increased circulating tumor necrosis factor level J:111432
increased eosinophil cell number J:111432
increased interleukin-5 secretion J:111432
lung inflammation J:111432
Hcktm1Hev/Hcktm1Hev
(involves: 129S7/SvEvBrd * C57BL/6J)
impaired macrophage phagocytosis J:16994
Hcktm1Hev/Hcktm1Hev
(B6.129S7-Hcktm1Hev)
abnormal inflammatory response J:113463
abnormal neutrophil physiology J:113463
Hcktm1Hev/Hcktm1Hev
Srctm1Sor/Srctm1Sor

(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal immune system organ morphology J:31647
abnormal spleen germinal center morphology J:31647
abnormal spleen morphology J:31647
abnormal splenic cell ratio J:31647
decreased leukocyte cell number J:31647
increased macrophage cell number J:31647
lymph node hypoplasia J:31647
thymus hypoplasia J:31647
Hcls1tm1Wtn/Hcls1tm1Wtn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:28146
abnormal humoral immune response J:28146
decreased B cell number J:28146
decreased T cell proliferation J:28146
Hcls1tm1Wtn/Hcls1tm1Wtn
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal negative T cell selection J:28146
decreased double-positive T cell number J:28146
Hcls1tm2Wtn/Hcls1tm2Wtn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:28146
abnormal humoral immune response J:28146
decreased B cell number J:28146
decreased T cell proliferation J:28146
Hcn2m1Btlr/Hcn2m1Btlr
(C57BL/6J-Hcn2m1Btlr)
decreased CD8-positive, alpha-beta T cell number J:255187
increased CD4-positive, alpha-beta T cell number J:255187
Hcrttm1.1(KOMP)Vlcg/Hcrttm1.1(KOMP)Vlcg
(C57BL/6N-Hcrttm1.1(KOMP)Vlcg/Ucd)
increased lymphocyte cell number J:211773
Hcsttm1.1Cln/Hcsttm1.1Cln
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:80426
immune system phenotype J:80426
impaired natural killer cell mediated cytotoxicity J:80426
Hcsttm1.1Cln/Hcsttm1.1Cln
(involves: 129P2/OlaHsd * C57BL/6)
decreased interferon-gamma secretion J:100668
decreased uterine NK cell number J:100668
Hcsttm1.1Cln/Hcsttm1.1Cln
(B6.129P2-Hcsttm1.1Cln)
abnormal osteoclast differentiation J:147155
abnormal osteoclast physiology J:147155
decreased osteoclast cell number J:147155
Hcsttm1.1Cln/Hcsttm1.1Cln
Tyrobptm1Lll/Tyrobptm1Lll

(B6.Cg-Hcsttm1.1Cln Tyrobptm1Lll)
abnormal NK T cell physiology J:147867
abnormal response to infection J:147867
Hcsttm1.1Dnax/Hcsttm1.1Dnax
(involves: C57BL/6)
abnormal NK T cell physiology J:147867, J:148086
abnormal response to infection J:147867
decreased interferon-gamma secretion J:147867
immune system phenotype J:148086
impaired natural killer cell mediated cytotoxicity J:148086
increased interferon-gamma secretion J:148086
increased interleukin-4 secretion J:148086
increased spleen weight J:148086
increased susceptibility to experimental autoimmune encephalomyelitis J:148086
Hdac1tm1.1Pmt/Hdac1tm1.1Pmt
Hdac2tm1.1Pmt/Hdac2tm1.1Pmt
Cd79atm1(cre)Reth/Cd79a+

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * FVB/N)
abnormal spleen morphology J:157903
arrested B cell differentiation J:157903
decreased B cell number J:157903
decreased pre-B cell number J:157903
decreased pro-B cell number J:157903
increased B cell apoptosis J:157903
Hdac1tm1.1Pmt/Hdac1tm1.1Pmt
Hdac2tm1.1Pmt/Hdac2tm1.1Pmt
Tg(Fcer2a-cre)5Mbu/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N)
decreased B cell proliferation J:157903
increased B cell apoptosis J:157903
Hdac1tm1.1Shmc/Hdac1+
Hdac2tm1.1Shmc/Hdac2tm1.1Shmc
Tg(Lck-cre)1Cwi/0

(involves: 129S7/SvEvBrd)
immune system phenotype J:194769
Hdac1tm1.1Shmc/Hdac1tm1.1Shmc
Hdac2tm1.1Shmc/Hdac2+
Tg(Lck-cre)1Cwi/0

(involves: 129S7/SvEvBrd)
arrested T cell differentiation J:194769
decreased CD4-positive, alpha-beta T cell number J:194769
decreased CD8-positive, alpha-beta T cell number J:194769
decreased double-positive T cell number J:194769
enlarged spleen J:194769
enlarged thymus J:194769
increased double-negative T cell number J:194769
increased double-positive T cell number J:194769
increased single-positive T cell number J:194769
thymus hypoplasia J:194769
Hdac1tm1.1Shmc/Hdac1tm1.1Shmc
Hdac2tm1.1Shmc/Hdac2tm1.1Shmc
Tg(Lck-cre)1Cwi/0

(involves: 129S7/SvEvBrd)
abnormal thymus corticomedullary boundary morphology J:194769
arrested T cell differentiation J:194769
decreased double-positive T cell number J:194769
decreased thymocyte number J:194769
enlarged spleen J:194769
enlarged thymus J:194769
increased double-positive T cell number J:194769
increased single-positive T cell number J:194769
increased T cell proliferation J:194769
increased thymocyte apoptosis J:194769
increased thymocyte number J:194769
Hdac1tm1.1Shmc/Hdac1tm1.1Shmc
Tg(Lck-cre)1Cwi/0

(involves: 129S7/SvEvBrd)
immune system phenotype J:194769
Hdac2tm1.1Shmc/Hdac2tm1.1Shmc
Tg(Lck-cre)1Cwi/0

(involves: 129S7/SvEvBrd)
immune system phenotype J:194769
Hdac4em1(IMPC)Ccpcz/Hdac4+
(C57BL/6N-Hdac4em1(IMPC)Ccpcz/Ccpcz)
increased NK cell number J:211773
Hdac6tm1.1Pmt/Y
(involves: 129P2/OlaHsd * C57BL/6)
decreased IgG level J:132629
decreased IgM level J:132629
immune system phenotype J:132629
Hdac6tm1.1Pmt/Hdac6tm1.1Pmt
(involves: 129P2/OlaHsd * C57BL/6)
decreased IgG level J:132629
decreased IgM level J:132629
immune system phenotype J:132629
Hdac6tm1.1Pmt/Hdac6tm1.1Pmt
(involves: 129P2/OlaHsd)
decreased circulating interleukin-10 level J:228570
decreased interleukin-10 secretion J:228570
Hdac11tm1.2Mrl/Hdac11tm1.2Mrl
(involves: C57BL/6NTac)
decreased interferon-gamma secretion J:222335
increased interleukin-10 secretion J:228570
Hdctm1Nagy/Hdctm1Nagy
(involves: 129S1/Sv * 129X1/SvJ)
abnormal mast cell morphology J:70702
decreased mast cell histamine storage J:70702
decreased mast cell number J:70702
decreased mast cell protease storage J:70702
Hddc2em1(IMPC)H/Hddc2em1(IMPC)H
(C57BL/6NTac-Hddc2em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Hddc3tm1.1(KOMP)Vlcg/Hddc3tm1.1(KOMP)Vlcg
(C57BL/6N-Hddc3tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Hectd1tm1b(EUCOMM)Hmgu/Hectd1+
(C57BL/6N-Hectd1tm1b(EUCOMM)Hmgu/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Hectd3tm1(NCOM)Cmhd/Hectd3tm1(NCOM)Cmhd
(C57BL/6N-Hectd3tm1(NCOM)Cmhd/Nju)
small spleen J:211773
small thymus J:211773
Hectd3tm1Lex/Hectd3tm1Lex
(FVB.129S5(B6)-Hectd3tm1Lex)
decreased circulating interferon-beta level J:266602
decreased circulating interleukin-1 beta level J:266602
decreased circulating interleukin-6 level J:266602
decreased circulating tumor necrosis factor level J:266602
decreased susceptibility to bacterial infection J:266602
decreased susceptibility to bacterial infection induced morbidity/mortality J:266602
Heg1tm1Mlkn/Heg1tm1Mlkn
(either: B6.129-Heg1tm1Mlkn or (involves: 129 * C57BL/6))
abnormal lymph circulation J:146528
abnormal lymphatic vessel endothelium morphology J:146528
lymphangiectasis J:146528
Helbtm1(KOMP)Vlcg/Helbtm1(KOMP)Vlcg
(involves: C57BL/6NTac)
immune system phenotype J:231089
Hellstm1a(EUCOMM)Wtsi/Hellstm1a(EUCOMM)Wtsi
(C57BL/6N-Hellstm1a(EUCOMM)Wtsi/Ieg)
decreased granulocyte number J:165965
decreased IgG1 level J:165965
Hellstm1Kmu/Hellstm1Kmu
(involves: 129S1/Sv)
decreased B cell number J:61948
increased CD8-positive, alpha-beta T cell number J:61948
increased double-negative T cell number J:61948
small spleen J:61948
small thymus J:61948
Hellstm1Rarc/Hellstm1Rarc
(involves: 129X1/SvJ * C57BL/6J)
small thymus J:107145
thymus hypoplasia J:107145
Helqem1(IMPC)Mbp/Helqem1(IMPC)Mbp
(C57BL/6N-Helqem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
hem1/hem1
(Not Specified)
decreased leukocyte cell number J:85113
hem2/hem2
(Not Specified)
decreased leukocyte cell number J:85113
Hephem1(IMPC)Ccpcz/Y
(C57BL/6NCrl-Hephem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Hephem1(IMPC)Ccpcz/Hephem1(IMPC)Ccpcz
(C57BL/6NCrl-Hephem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Hephl1cw-thd/Hephl1cw-thd
(SJL/J)
abnormal humoral immune response J:15004
Hephl1cw/Hephl1cw
(CWD/LeJ)
abnormal immune system morphology J:24875
abnormal lymph node morphology J:24875
abnormal spleen morphology J:24875
enlarged spleen J:24875
enlarged thymus J:24875
Herc1em3(IMPC)Wtsi/Herc1em3(IMPC)Wtsi
(C57BL/6N-Herc1em3(IMPC)Wtsi/Wtsi)
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased Ly6C high monocyte number J:211773
increased Ly6C low monocyte number J:211773
increased monocyte cell number J:211773
Herc4tm1b(KOMP)Wtsi/Herc4tm1b(KOMP)Wtsi
(C57BL/6N-Herc4tm1b(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Herc6tm1b(EUCOMM)Hmgu/Herc6tm1b(EUCOMM)Hmgu
(C57BL/6N-Herc6tm1b(EUCOMM)Hmgu/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Herc6tm1Kshim/Herc6tm1Kshim
(either: B6.Cg-Herc6tm1Kshim or (involves: C57BL/6NCrlj * CBA/JNCrlj))
immune system phenotype J:330459
Hes1tm1.1Frad/Hes1tm1.1Frad
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
immune system phenotype J:167000
Hes1tm1.1Frad/Hes1tm1.1Frad
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6)
immune system phenotype J:167000
Hes1tm1.1Frad/Hes1tm1.1Frad
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal T cell differentiation J:167000
decreased DN1 thymic pro-T cell number J:167000
decreased DN2 thymocyte number J:167000
decreased DN3 thymocyte number J:167000
decreased DN4 thymocyte number J:167000
decreased double-positive T cell number J:167000
decreased gamma-delta T cell number J:167000
increased DN1 thymic pro-T cell number J:167000
increased immature B cell number J:167000
thymus hypoplasia J:167000
Hexbtm1b(EUCOMM)Hmgu/Hexbtm1b(EUCOMM)Hmgu
(C57BL/6N-Hexbtm1b(EUCOMM)Hmgu/H)
increased monocyte cell number J:211773
Hexbtm1Rlp/Hexbtm1Rlp
(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
CNS inflammation J:90687
increased circulating interleukin-4 level J:87617
increased immunoglobulin level J:87617
Hexbtm1Rlp/Hexbtm1Rlp
Tg(Hexb-tTA2S,tetO-Hexb)#Tjsa/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
microgliosis J:190450
Hexbtm1Rlp/Hexbtm1Rlp
Tg(SYN1-tTA2S,tetO-Hexb)#Tjsa/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
microgliosis J:190450
Hfetm1.1Wsr/Hfetm1.1Wsr
(involves: 129P2/OlaHsd * C57BL/6)
decreased spleen iron level J:132134
Hfetm1Gfn/Hfetm1Gfn
(involves: 129P2/OlaHsd * C57BL/6)
increased osteoclast cell number J:262906
increased spleen iron level J:68025
Hfetm1Wsr/Hfetm1Wsr
Tg(Alb1-cre)7Gsc/?

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
decreased spleen iron level J:132134
Hfetm2Nca/Hfetm2Nca
(involves: 129S6/SvEvTac)
decreased spleen iron level J:78536
Hfetm2Nca/Hfetm2Nca
(involves: 129S6/SvEvTac * C57BL/6J)
decreased spleen iron level J:78536
Hfgi1C57BL/6Ola/?
(involves: C57BL/6Ola * BALB/cOla)
abnormal lymphopoiesis J:123483
stomach inflammation J:123483
Hfgi2C57BL/6Ola/?
(involves: C57BL/6Ola * BALB/cOla)
abnormal lymphopoiesis J:123483
stomach inflammation J:123483
Hgsnatem4(IMPC)Tcp/Hgsnatem4(IMPC)Tcp
(C57BL/6NCrl-Hgsnatem4(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Hgsnattm1a(EUCOMM)Wtsi/Hgsnattm1a(EUCOMM)Wtsi
(involves: C57BL/6N * C57BL/6NTac)
abnormal Kupffer cell morphology J:235361
enlarged spleen J:235361
increased spleen weight J:235361
microgliosis J:235361
Hhextm1Ngu/Hhextm1Ngu
(involves: 129/Sv * C57BL/6)
abnormal monocyte differentiation J:65105
Hhiptm1Amc/Hhiptm1Amc
(involves: 129S1/Sv * 129X1/SvJ)
abnormal spleen morphology J:85472
small spleen J:85472
Hic1tm1Sbb/Hic1+
(involves: 129S4/SvJae * C57BL/6)
dermatitis J:81448
Hif1atm1Kats/Hif1atm1Kats
(involves: 129 * C57BL/6)
abnormal cytokine level J:117857
abnormal interleukin secretion J:117857
increased interferon-gamma secretion J:117857
increased tumor necrosis factor secretion J:117857
Hif1atm3Rsjo/Hif1atm3Rsjo
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Hprt1tm1(Pck1-cre)Vhh/Y

(involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ)
kidney inflammation J:130751
Hif1atm3Rsjo/Hif1atm3Rsjo
Hprt1tm1(Pck1-cre)Vhh/Y
Vhltm1Jae/Vhltm1Jae

(involves: 129 * BALB/c * C57BL/6)
kidney inflammation J:106705
Hif1atm3Rsjo/Hif1atm3Rsjo
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
abnormal leukocyte physiology J:117348
abnormal macrophage physiology J:107682
decreased inflammatory response J:107682
decreased susceptibility to induced arthritis J:107682
decreased tumor necrosis factor secretion J:107682
impaired macrophage chemotaxis J:107682
Hif1atm3Rsjo/Hif1atm3Rsjo
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased interleukin-1 alpha secretion J:148597
decreased interleukin-1 beta secretion J:148597
decreased interleukin-6 secretion J:148597
decreased interleukin-12 secretion J:148597
decreased susceptibility to endotoxin shock J:148597
decreased tumor necrosis factor secretion J:148597
Hif1atm3Rsjo/Hif1atm3Rsjo
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129S1/Sv * 129X1/SvJ)
immune system phenotype J:119731
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Fabp1-cre)1Jig/0

(involves: 129S1/Sv * 129X1/SvJ * BALB/c * FVB/N)
increased susceptibility to induced colitis J:93476
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Itgax-cre)1-1Reiz/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal dendritic cell number J:187773
abnormal leukocyte migration J:187773
immune system phenotype J:187773
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Lck-cre)1Jtak/0

(involves: 129S1/Sv * 129X1/SvJ)
increased interferon-gamma secretion J:117857
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Tal1-cre/ERT)42-056Jrg/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal B cell differentiation J:192126
abnormal T cell differentiation J:192126
Hif1anem1(IMPC)Mbp/Hif1anem1(IMPC)Mbp
(C57BL/6N-Hif1anem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Hip1tm4Tsr/Hip1+
Runx1tm3Dow/Runx1+
Tg(Mx1-cre)1Cgn/0

(involves: 129X1/SvJ * C57BL/6 * CBA)
abnormal myelopoiesis J:151974
abnormal spleen B cell follicle morphology J:151974
abnormal spleen morphology J:151974
enlarged spleen J:151974
increased granulocyte number J:151974
increased leukocyte cell number J:151974
increased neutrophil cell number J:151974
increased spleen red pulp amount J:151974
increased spleen weight J:151974
spleen hyperplasia J:151974
Hip1tm4Tsr/Hip1+
Tg(Mx1-cre)1Cgn/0

(involves: 129X1/SvJ * C57BL/6 * CBA)
abnormal myelopoiesis J:151974
abnormal spleen morphology J:151974
enlarged spleen J:151974
increased spleen red pulp amount J:151974
Hiratm1a(EUCOMM)Wtsi/Hira+
(C57BL/6N-Hiratm1a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:175295
Hirip3tm1.1(KOMP)Mbp/Hirip3tm1.1(KOMP)Mbp
(C57BL/6N-Hirip3tm1.1(KOMP)Mbp/Ucd)
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Hivep2tm1Sis/Hivep2+
(involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj)
decreased CD8-positive, alpha-beta T cell number J:72249
decreased single-positive T cell number J:72249
Hivep2tm1Sis/Hivep2tm1Sis
(involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj)
abnormal immune system cell morphology J:72249
abnormal thymus cortex morphology J:72249
abnormal thymus lobule morphology J:72249
abnormal thymus medulla morphology J:72249
decreased single-positive T cell number J:72249
enlarged thymus cortex J:72249
Hivep2tm1Sis/Hivep2tm1Sis
(C.Cg-Hivep2tm1Sis)
abnormal T-helper 2 cell morphology J:96024
Hivep2tm1Sis/Hivep2tm1Sis
(either: (involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj) or (involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj))
CNS inflammation J:263351
Hivep2tm1Sis/Hivep2tm1Sis
Tg(DO11.10)10Dlo/?

(involves: BALB/cA * C3H * C57BL/6NCrlj * CBA/JNCrlj)
abnormal positive T cell selection J:96024
abnormal T-helper 2 cell morphology J:96024
decreased single-positive T cell number J:72249
Hivep3tm1Glm/Hivep3tm1Glm
(involves: 129 * C57BL/6)
decreased interleukin-2 secretion J:100058
Hivep3tm1Glm/Hivep3tm1Glm
(Not Specified)
abnormal osteoclast differentiation J:184764
abnormal osteoclast physiology J:184764
decreased osteoclast cell number J:184764
Hivep3tm1Lcw/Hivep3tm1Lcw
(chimera involves: 129S/SvEv * 129X1/SvJ)
decreased double-positive T cell number J:79652
Hjvtm1Arbr/Hjvtm1Arbr
(involves: 129S4/SvJae * 129X1/SvJ)
decreased spleen iron level J:100173
Hjvtm1Kpan/Hjvtm1Kpan
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129S6/SvEvTac * C57BL/6)
abnormal macrophage morphology J:231428
decreased spleen iron level J:231428
Hjvtm1Nca/Hjvtm1Nca
(involves: 129S4/SvJae * 129S6/SvEvTac)
decreased spleen iron level J:100178
Hjvtm1Nca/Hjvtm1Nca
(involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
abnormal macrophage morphology J:160248
decreased spleen iron level J:160248
Hjvtm1Nca/Hjvtm1Nca
Tmprss6tm1Dgen/Tmprss6+

(involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
abnormal macrophage morphology J:160248
decreased spleen iron level J:160248
Hjvtm1Nca/Hjvtm1Nca
Tmprss6tm1Dgen/Tmprss6tm1Dgen

(involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
abnormal macrophage morphology J:160248
decreased spleen iron level J:160248
Hk1dea/Hk1dea
(A/J-Hk1dea/J)
abnormal spleen morphology J:72146
increased spleen red pulp amount J:72146
increased spleen weight J:72146
Hk3em1(IMPC)Tcp/Hk3em1(IMPC)Tcp
(C57BL/6N-Hk3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Hlb18/?
(C57BL/6J-Hlb18)
increased leukocyte cell number J:82961
Hlb95/?
(C57BL/6J-Hlb95)
increased leukocyte cell number J:82961
Hlb141/?
(C57BL/6J-Hlb141)
decreased leukocyte cell number J:82961
decreased neutrophil cell number J:82961
hlb145/?
(C57BL/6J-hlb145/J)
decreased leukocyte cell number J:82961
hlb156/?
(C57BL/6J-hlb156/J)
decreased neutrophil cell number J:82961
hlb258/?
(involves: 129S4/SvJae * C57BL/6J)
decreased circulating fibrinogen level J:82961
hlb385/?
(C57BL/6J-hlb385/J)
decreased leukocyte cell number J:82961
Hltftm1.1Hdin/Hltftm1.1Hdin
ShprhGt(RRJ453)Byg/ShprhGt(RRJ453)Byg

(involves: 129 * C57BL/6 * SJL)
immune system phenotype J:177630
Hltftm1.1Hdin/Hltftm1.1Hdin
Shprhtm1Jhjh/Shprhtm1Jhjh

(involves: 129 * C57BL/6 * SJL)
immune system phenotype J:177630
Hmbox1em1(IMPC)Tcp/Hmbox1em1(IMPC)Tcp
(C57BL/6N-Hmbox1em1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
Hmga1tm1Afus/Hmga1+
(involves: 129S7/SvEvBrd * C57BL/6)
enlarged spleen J:106702
Hmga1tm1Afus/Hmga1tm1Afus
(involves: 129S7/SvEvBrd * C57BL/6)
enlarged spleen J:106702
lymphoid hyperplasia J:106702
myeloid hyperplasia J:106702
Hmgb1tm1.1Dltg/Hmgb1tm1.1Dltg
Tg(Pdx1-cre)6Tuv/0

(involves: C57BL/6 * FVB/N)
increased circulating interleukin-6 level J:225260
increased circulating tumor necrosis factor level J:225260
increased susceptibility to induced pancreatitis J:225260
Hmgb1tm1.1Ttg/Hmgb1tm1.1Ttg
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
abnormal macrophage physiology J:205499
decreased macrophage cell number J:205499
impaired macrophage phagocytosis J:205499
increased circulating interleukin-1 beta level J:205499
increased circulating interleukin-18 level J:205499
increased interleukin-1 beta secretion J:205499
increased interleukin-18 secretion J:205499
increased macrophage apoptosis J:205499
increased susceptibility to bacterial infection J:205499
increased susceptibility to endotoxin shock J:205499
Hmgb1tm1.1Ttg/Hmgb1tm1.1Ttg
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129P2/OlaHsd * C57BL/6 * DBA)
increased circulating interleukin-1 beta level J:205499
increased circulating interleukin-18 level J:205499
Hmgb1tm1.1Ttg/Hmgb1tm1.1Ttg
Tg(Itgax-cre)1-1Reiz/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
increased circulating interleukin-1 beta level J:205499
increased circulating interleukin-18 level J:205499
Hmgb3tm1Dmb/Y
(involves: 129S6/SvEvTac * 129X1/SvJ)
abnormal leukopoiesis J:96514
Hmgn5tm1.2Mbus/Y
(involves: 129S4/SvJae * C57BL/6J)
decreased granulocyte number J:199604
decreased IgE level J:199604
increased CD8-positive, alpha-beta T cell number J:199604
increased IgA level J:199604
Hmgn5tm1.2Mbus/Hmgn5tm1.2Mbus
(involves: 129S4/SvJae * C57BL/6J)
decreased granulocyte number J:199604
decreased IgE level J:199604
increased CD8-positive, alpha-beta T cell number J:199604
increased IgA level J:199604
Hmgxb3tm1a(EUCOMM)Wtsi/Hmgxb3tm1a(EUCOMM)Wtsi
(C57BL/6N-Hmgxb3tm1a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Hmox1tm1.1Gkl/Hmox1tm1.1Gkl
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * 129P2/OlaHsd * BALB/cJ * C57BL/6)
decreased interferon-beta secretion J:148498
decreased susceptibility to bacterial infection induced morbidity/mortality J:148498
decreased susceptibility to Paramyxoviridae infection J:148498
increased B cell number J:148498
increased CD4-positive, alpha-beta T cell number J:148498
increased CD8-positive, alpha-beta T cell number J:148498
increased circulating tumor necrosis factor level J:148498
increased granulocyte number J:148498
increased interferon-gamma secretion J:148498
increased macrophage cell number J:148498
increased splenocyte proliferation J:148498
increased susceptibility to experimental autoimmune encephalomyelitis J:148498
Hmox1tm1.1Hes/Hmox1tm1.1Hes
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N)
decreased inflammatory response J:214639
decreased interleukin-1 beta secretion J:214639
decreased interleukin-6 secretion J:214639
decreased tumor necrosis factor secretion J:214639
Hmox1tm1.2Gkl/Hmox1tm1.2Gkl
(involves: 129 * BALB/cJ * C57BL/6)
enlarged spleen J:148498
increased inflammatory response J:148498
liver inflammation J:148498
Hmox1tm1Mlee/Hmox1tm1Mlee
(involves: 129S2/SvPas * BALB/c)
increased susceptibility to parasitic infection J:153083
increased susceptibility to parasitic infection induced morbidity/mortality J:153083
Hmox1tm1Poss/Hmox1+
Slc48a1em1Ih/Slc48a1em1Ih

(involves: 129 * 129S2/SvPas * C57BL/6J)
decreased macrophage cell number J:282829
Hmox1tm1Poss/Hmox1tm1Poss
(involves: 129S2/SvPas * C57BL/6)
abnormal leukocyte cell number J:79254
abnormal lymph node cell ratio J:79254
abnormal splenic cell ratio J:79254
chronic inflammation J:79254
enlarged lymph nodes J:79254
enlarged spleen J:79254
glomerulonephritis J:79254
liver inflammation J:79254
lung inflammation J:79254
spleen hyperplasia J:79254
Hmox1tm1Poss/Hmox1tm1Poss
(involves: 129 * 129S2/SvPas * C57BL/6J)
decreased macrophage cell number J:282829
Hmox1tm1Poss/Hmox1tm1Poss
Slc48a1em1Ih/Slc48a1em1Ih

(involves: 129 * 129S2/SvPas * C57BL/6J)
decreased macrophage cell number J:282829
Hmox1tm1Poss/Hmox1tm1Poss
Spictm2Kmm/Spictm2Kmm

(involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * FVB/N)
decreased macrophage cell number J:210804
Hmox2tm1b(EUCOMM)Hmgu/Hmox2tm1b(EUCOMM)Hmgu
(C57BL/6N-Hmox2tm1b(EUCOMM)Hmgu/H)
decreased monocyte cell number J:211773
increased spleen weight J:211773
Hnf1btm1Mya/Hnf1btm3Mya
Tg(Alb1-cre)7Gsc/0

(involves: 129S2/SvPas * C57BL/6 * FVB/N)
liver inflammation J:75935
Hnf1btm2Ics/Hnf1b+
(involves: 129 * C57BL/6N)
chronic pancreas inflammation J:306082
Hnrnpa2b1tm1.1Caox/Hnrnpa2b1tm1.1Caox
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
abnormal interferon level J:283622
decreased circulating interferon-beta level J:283622
decreased interferon-beta secretion J:283622
immune system phenotype J:283622
increased susceptibility to Herpesvirales infection J:283622
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:283622
Hnrnpdtm1b(KOMP)Wtsi/Hnrnpd+
(C57BL/6N-Hnrnpdtm1b(KOMP)Wtsi/Nju)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Hnrnpdtm1Rjsc/Hnrnpdtm1Rjsc
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal macrophage physiology J:116112
increased circulating tumor necrosis factor level J:116112
increased susceptibility to bacterial infection J:116112
increased susceptibility to endotoxin shock J:116112
Hnrnph1tm1b(KOMP)Wtsi/Hnrnph1+
(C57BL/6N-Hnrnph1tm1b(KOMP)Wtsi/Nju)
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Hnrnpltm1.1Tmo/Hnrnpltm1.1Tmo
Tg(Lck-cre)548Jxm/0

(B6.Cg-Hnrnpltm1.1Tmo Tg(Lck-cre)548Jxm)
abnormal T cell differentiation J:188749
decreased CD4-positive, alpha-beta T cell number J:188749
decreased CD8-positive, alpha-beta T cell number J:188749
decreased double-positive T cell number J:188749
decreased T cell number J:188749
increased double-negative T cell number J:188749
increased T cell proliferation J:188749
thymus hypoplasia J:188749
Hnrnpllthdr/Hnrnpllthdr
(C57BL/6JSfdAnu-Hnrnpllthdr/Anu)
abnormal memory T cell morphology J:142641
abnormal memory T cell physiology J:142641
abnormal T cell differentiation J:142641
decreased CD4-positive, alpha-beta T cell number J:142641
Hook1em1(IMPC)Tcp/Hook1em1(IMPC)Tcp
(C57BL/6NCrl-Hook1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
small spleen J:211773
Hook2em1(IMPC)Tcp/Hook2em1(IMPC)Tcp
(C57BL/6N-Hook2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Hook3tm1b(NCOM)Mfgc/Hook3tm1b(NCOM)Mfgc
(C57BL/6N-Hook3tm1b(NCOM)Mfgc/Tcp)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
(involves: 129S1/Sv * 129X1/SvJ)
thymus hypoplasia J:178887
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
Hoxb1tm3Mrc/Hoxb1+

(involves: 129S1/Sv * 129X1/SvJ)
small thymus J:41540
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
Hoxb1tm3Mrc/Hoxb1tm3Mrc

(involves: 129S1/Sv * 129X1/SvJ)
athymia J:41540
Hoxa3tm1Kth/Hoxa3tm1Kth
(involves: 129S1/Sv * 129X1/SvJ)
athymia J:60296
Hoxa3tm1Kth/Hoxa3tm1Kth
Hoxd3tm3(Hoxa3)Mrc/Hoxd3+

(involves: 129S1/Sv * 129X1/SvJ)
athymia J:60296
Hoxa3tm1Kth/Hoxa3tm2(Hoxd3)Mrc
(involves: 129S1/Sv * 129X1/SvJ)
immune system phenotype J:60296
Hoxa3tm1Mrc/Hoxa3+
Hoxb3tm1Mrc/Hoxb3tm1Mrc

(involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J)
ectopic thymus J:46523
Hoxa3tm1Mrc/Hoxa3+
Hoxd3tm1Mrc/Hoxd3tm1Mrc

(involves: 129S7/SvEvBrd * C57BL/6J)
ectopic thymus J:46523
Hoxa3tm1Mrc/Hoxa3tm1Mrc
(involves: 129S7/SvEvBrd)
athymia J:17753, J:161296
Hoxa3tm1Mrc/Hoxa3tm1Mrc
Hoxd3tm1Mrc/Hoxd3tm1Mrc

(involves: 129S7/SvEvBrd * C57BL/6J)
athymia J:19447
Hoxa3tm1Mrc/Hoxa3tm2Nrm
(involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd)
athymia J:161296
Hoxa3tm1Mrc/Hoxa3tm3.1Nrm
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129S7/SvEvBrd * C57BL/6J * CBA/J)
ectopic thymus J:161296
Hoxa3tm1Nrm/Hoxa3tm1Mrc
(involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NHsd)
athymia J:161296
Hoxa3tm1Nrm/Hoxa3tm1Nrm
(involves: C3H * C57BL/6 * C57BL/6NHsd)
athymia J:161296
Hoxa3tm2(Hoxd3)Mrc/Hoxa3tm2(Hoxd3)Mrc
(involves: 129S1/Sv * 129X1/SvJ)
immune system phenotype J:60296
Hoxa3tm2Nrm/Hoxa3tm2Nrm
(involves: C3H * C57BL/6 * C57BL/6NHsd)
athymia J:161296
Hoxa3tm2Nrm/Hoxa3tm3.1Nrm
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: C3H * C57BL/6 * CBA/J)
ectopic thymus J:161296
Hoxa5tm1Rob/Hoxa5tm1Rob
(involves: 129S/SvEv * C57BL/6 * MF1)
abnormal alveolar macrophage morphology J:113378
lung inflammation J:113378
Hoxa7tm1Mrc/Hoxa7tm1Mrc
Hoxb7tm1Mrc/Hoxb7tm1Mrc

(involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ)
small thymus J:50942
Hoxa9tm1Mrc/Hoxa9tm1Mrc
(B6.129S7-Hoxa9tm1Mrc)
decreased spleen weight J:126371
spleen hypoplasia J:126371
Hoxb4tm1.1Karl/Hoxb4tm1.1Karl
(involves: 129 * C57BL/6J)
spleen hypoplasia J:90976
Hoxb6tm1Cka/Hoxb6tm1Cka
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:133561
Hoxb8tm1.1Mrc/Hoxb8tm1.1Mrc
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
abnormal microglial cell morphology J:162102
Hoxb9tm1Mrc/Hoxb9tm1Mrc
(involves: 129S7/SvEvBrd)
small thymus J:37847
Hoxc4tm2.1Mrc/Hoxc4tm2.1Mrc
(involves: 129S/SvEv * C57BL/6)
abnormal class switch recombination J:148278
abnormal somatic hypermutation frequency J:148278
decreased IgA level J:148278
decreased IgE level J:148278
decreased IgG1 level J:148278
decreased IgG2a level J:148278
decreased IgG2b level J:148278
decreased IgG3 level J:148278
decreased IgM level J:148278
immune system phenotype J:148278
Hptm1Skl/Hptm1Skl
Hpxtm1Altr/Hpxtm1Altr

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6J)
enlarged spleen J:80539
increased spleen red pulp amount J:80539
liver inflammation J:80539
Hpgdstm1Urad/Hpgdstm1Urad
(B6.129-Hpgdstm1Urad)
abnormal cytokine secretion J:107651
abnormal lymph node morphology J:107651
increased acute inflammation J:107651
increased inflammatory response J:107651
increased susceptibility to type I hypersensitivity reaction J:197334
Hpi1C57BL/6J/?
(involves: A/J * C57BL/6J)
abnormal inflammatory response J:69153
Hpi1C57BL/6J/Hpi1C57BL/6J
Hpi2C57BL/6J/Hpi2C57BL/6J

(involves: A/J * C57BL/6J)
abnormal inflammatory response J:69153
Hpi2C57BL/6J/?
(involves: A/J * C57BL/6J)
abnormal inflammatory response J:69153
Hprt1b-m3/Y
Impdh1tm1Bmi/Impdh1tm1Bmi

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal lymphopoiesis J:85443
decreased cytotoxic T cell cytolysis J:85443
decreased interleukin-4 secretion J:85443
decreased splenocyte proliferation J:85443
decreased T cell proliferation J:85443
Hprt1b-m3/Y
Impdh2tm1Bmi/Impdh2+

(involves: 129P2/OlaHsd)
abnormal cytotoxic T cell physiology J:86045
abnormal lymphocyte cell number J:86045
Hprt1tm1(CAG-Tgfbr1*)Lba/Y
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
abnormal T cell activation J:148747
Hprt1tm1(CAG-Tgfbr1*)Lba/Y
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Cd4-cre)1Cwi/0

(involves: 129 * 129S6/SvEvTac * C57BL/6 * DBA/2)
immune system phenotype J:148747
Hprt1tm1(CAG-Tgfbr1*)Lba/Hprt1tm1(CAG-Tgfbr1*)Lba
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
abnormal T cell activation J:148747
Hprt1tm1(CAG-Tgfbr1*)Lba/Hprt1tm1(CAG-Tgfbr1*)Lba
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Cd4-cre)1Cwi/0

(involves: 129 * 129S6/SvEvTac * C57BL/6 * DBA/2)
immune system phenotype J:148747
Hprt1tm1(CUX1)Anep/Hprt1+
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * FVB))
abnormal spleen white pulp morphology J:113393
abnormal splenic cell ratio J:113393
decreased B cell number J:113393
enlarged lymph nodes J:113393
enlarged spleen J:113393
increased leukocyte cell number J:113393
increased neutrophil cell number J:113393
myeloid hyperplasia J:113393
spleen hyperplasia J:113393
Hprt1tm1(Pck1-cre)Vhh/Y
Vhltm1Jae/Vhltm1Jae

(involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6)
kidney inflammation J:106705
Hprt1tm2(CUX1)Anep/Hprt1+
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * FVB))
immune system phenotype J:113393
Hps1ep/Hps1ep
(involves: C3HeB/FeJ * C57BL/6J)
abnormal macrophage physiology J:7869
Hps1ep/Hps1ep
(B6.C3Fe-Hps1ep/J)
abnormal NK cell physiology J:6801
alveolitis J:110157
Hps3coa-Btlr/Hps3coa-Btlr
(C57BL/6J-Hps3coa-Btlr)
immune system phenotype J:137495
Hps5ru2-2Btlr/Hps5ru2-2Btlr
(C57BL/6J-Hps5ru2-2Btlr)
immune system phenotype J:135220
Hps5ru2-Btlr/Hps5ru2-Btlr
(C57BL/6J-Hps5ru2-Btlr)
increased susceptibility to bacterial infection J:133272
increased susceptibility to Herpesvirales infection J:133272
Hps6em1(IMPC)Tcp/Hps6em1(IMPC)Tcp
(C57BL/6N-Hps6em1(IMPC)Tcp/Tcp)
small spleen J:211773
small thymus J:211773
Hps6ru-2J/Hps6ru-2J
(C57BL/10J-Hps6ru-2J)
immune system phenotype J:6485
Hps6ru-Btlr/Hps6ru-Btlr
(C57BL/6J-Hps6ru-Btlr)
immune system phenotype J:137496
Hpsetm1.2Mdh/Hpsetm1.2Mdh
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal dendritic cell chemotaxis J:209913
abnormal Langerhans cell morphology J:209913
decreased acute inflammation J:209913
decreased leukocyte cell number J:209913
impaired eosinophil recruitment J:209913
increased eosinophil cell number J:209913
Hrem1(IMPC)H/Hrem1(IMPC)H
(C57BL/6NTac-Hrem1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Hrhr/Hrhr
(HRS/J)
decreased T cell number J:6087
decreased T cell proliferation J:6375
increased macrophage cell number J:150402
Hrhr/Hrhr
Tg(CD2-Stat6*V625A*T626A)78Mhk/0

(involves: C3H * SKH1)
blepharitis J:230018
eye inflammation J:230018
Meibomian gland inflammation J:230018
uveitis J:230018
Hrm1Btlr/Hrm1Btlr
(C57BL/6J-Hrm1Btlr)
immune system phenotype J:138686
Hrm1Enu/Hrm1Enu
(BALB/cJ-Hrm1Enu)
granulomatous inflammation J:108173
Hrrh-bmh/Hrrh-bmh
(involves: C57BL/6JRj * CBA/JRj)
immune system phenotype J:89321
Hrrh-R/Hrrh-R
(involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El)
decreased thymus weight J:156542
Hrrh/Hrrh
(Not Specified)
eye inflammation J:16021
Hrrh/Hrrh
(RHJ/LeJ)
thymus atrophy J:57947
Hrrhsl/Hrrhsl
(involves: BALB/c)
thymus atrophy J:98859
HrUSP/HrUSP
(either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2))
abnormal immunoglobulin level J:21316
abnormal lymph node secondary follicle morphology J:21316
abnormal thymus involution J:21316
decreased IgM level J:21316
enlarged inguinal lymph nodes J:21316
enlarged popliteal lymph nodes J:21316
glomerulonephritis J:21316
increased IgG level J:21316
increased susceptibility to autoimmune disorder J:21316
lymph node inflammation J:21316
lymph node medullary cord hyperplasia J:21316
thymus cortex atrophy J:21316
Hrgtm1Wja/Hrgtm1Wja
(involves: 129P2/OlaHsd * C57BL/6)
increased circulating fibrinogen level J:134621
increased monocyte cell number J:134621
Hrh1Bphs-r/Hrh1Bphs-r
(C3H/HeJ)
immune system phenotype J:4933, J:77938
Hrh1Bphs-r/Hrh1Bphs-s
((C3H/HeJ x SJL/J)F1)
abnormal immune system physiology J:77938
abnormal response to infection J:77938
increased susceptibility to bacterial infection J:77938
increased susceptibility to bacterial infection induced morbidity/mortality J:77938
Hrh1Bphs-s/Hrh1Bphs-s
(C3.SJL-Hrh1Bphs-s)
abnormal response to infection J:77938
increased susceptibility to bacterial infection J:77938
increased susceptibility to bacterial infection induced morbidity/mortality J:77938
Hrh1tm1Wtn/Hrh1tm1Wtn
(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell proliferation J:111704
decreased IgG3 level J:111704
decreased IgM level J:111704
decreased interferon-gamma secretion J:111704
decreased interleukin-2 secretion J:111704
decreased T cell number J:111704
decreased T cell proliferation J:111704
increased interleukin-4 secretion J:111704
Hrh1tm1Wtn/Hrh1tm1Wtn
(B6.129P2-Hrh1tm1Wtn)
decreased inflammatory response J:110367
decreased interferon-gamma secretion J:110367
decreased interleukin-5 secretion J:110367
decreased interleukin-13 secretion J:110367
increased IgG level J:110367
increased IgM level J:110367
Hrh3Eae8-r/?
(B10.S-H2s/SgMcdJ)
decreased susceptibility to experimental autoimmune encephalomyelitis J:34892
Hrh3Eae8-r/Hrh3Eae8-r
(involves: B10.S/DvTe * SJL/J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:49054
Hrh3Eae8-s/?
(involves: B10.S * SJL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:49054
Hrh3tm1Twl/Hrh3tm1Twl
(involves: 129P2/OlaHsd)
immune system phenotype J:132140
Hrh3tm1Twl/Hrh3tm1Twl
(B6.129X1-Hrh3tm1Twl)
increased susceptibility to experimental autoimmune encephalomyelitis J:122269
Hrh4tm1Lex/Hrh4+
(involves: 129S/SvEv * C57BL/6)
abnormal mast cell physiology J:132140
Hrh4tm1Lex/Hrh4tm1Lex
(involves: 129S/SvEv * C57BL/6)
abnormal mast cell physiology J:131785
Hrh4tm1Lex/Hrh4tm1Lex
(involves: 129S/SvEv * BALB/c)
abnormal chemokine level J:131785
abnormal dendritic cell physiology J:131785
abnormal interleukin level J:131785
decreased IgE level J:131785
decreased IgG1 level J:131785
decreased inflammatory response J:131785
Hrl129S6/SvEvTac/HrlC57BL/6J
(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to Herpesvirales infection J:86189
HrlC57BL/6J/HrlC57BL/6J
(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to Herpesvirales infection J:86189
Hs3st3b1em2(IMPC)Mbp/Hs3st3b1em2(IMPC)Mbp
(C57BL/6N-Hs3st3b1em2(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Hsd17b3tm1.2Mpo/Hsd17b3tm1.2Mpo
(involves: 129S6/SvEvTac * C57BL/6N * C57BL/6NCrl)
increased spleen weight J:301756
Hsd17b4em1(IMPC)Tcp/Hsd17b4em1(IMPC)Tcp
(C57BL/6NCrl-Hsd17b4em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Hsd17b4tm1Baes/Hsd17b4tm1Baes
(involves: 129S1/Sv * 129X1/SvJ)
microgliosis J:201698
Hsd17b4tm2Baes/Hsd17b4tm2Baes
Tg(Nes-cre)1Kln/0

(involves: 129 * C57BL/6 * SJL)
microgliosis J:201698
Hsd17b11Gt(OST237628)Lex/Hsd17b11Gt(OST237628)Lex
(B6;129S5-Hsd17b11Gt(OST237628)Lex/Mmucd)
increased IgG2a level J:171883
increased immature B cell number J:171883
Hsd17b13tm1Lex/Hsd17b13tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6N)
liver inflammation J:273927
Hsd17b14tm1Lex/Hsd17b14tm1Lex
(B6;129S5-Hsd17b14tm1Lex/Mmucd)
increased IgG2a level J:171883
Hsf1tm1Ijb/Hsf1tm1Ijb
(either: (involves: 129S6/SvEvTac * 129X1/SvJ) or (involves: 129S6/SvEvTac * BALB/c) or (involves: 129S6/SvEvTac * C57BL/6J) or (involves: 129S6/SvEvTac * ICR))
increased susceptibility to bacterial infection J:58383
increased tumor necrosis factor secretion J:58383
Hsf1tm1Ijb/Hsf1tm1Ijb
Tg(TTR-V30M)15Imeg/0

(involves: 129S6/SvEvTac * BALB/c * C57BL/6)
increased interleukin-1 beta secretion J:156658
increased tumor necrosis factor secretion J:156658
Hsf2bptm1b(EUCOMM)Hmgu/Hsf2bptm1b(EUCOMM)Hmgu
(C57BL/6N-Hsf2bptm1b(EUCOMM)Hmgu/Ieg)
enlarged lymph nodes J:211773
Hsh2dtm1Viss/Hsh2dtm1Viss
(B6.129-Hsh2dtm1Viss)
immune system phenotype J:111408
increased interleukin-2 secretion J:111408
increased T cell proliferation J:111408
Hsh2dtm1Viss/Hsh2dtm1Viss
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:111408
abnormal CD8-positive, alpha-beta T cell physiology J:111408
increased spleen weight J:111408
Hsp90aa1tm1.1Udon/Hsp90aa1tm1.1Udon
(involves: C57BL/6)
abnormal dendritic cell antigen presentation J:177143
abnormal dendritic cell physiology J:177143
decreased interferon-gamma secretion J:177143
Hsp90b1tm1Zhli/Hsp90b1tm1.1Zhli
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S/SvEv)
abnormal cytokine secretion J:118427
abnormal inflammatory response J:118427
abnormal macrophage physiology J:118427
increased susceptibility to bacterial infection J:118427
Hspa1btm1Clib/Hspa1btm1Clib
(involves: 129P2/OlaHsd * C57BL/6J)
increased interleukin-6 secretion J:76801
Hspa9Gt(IST14901H6)Tigm/Hspa9+
(involves: C57BL/6N)
decreased pre-B cell number J:227164
Hspa12atm1.1Zdi/Hspa12atm1.1Zdi
(involves: 129 * C57BL/6)
abnormal macrophage morphology J:302786
increased susceptibility to endotoxin shock J:302787
Hspa13tm1.1Smoc/Hspa13tm1.1Smoc
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S * C57BL/6)
abnormal class switch recombination J:303927
abnormal humoral immune response J:303927
abnormal plasmablast number J:303927
abnormal somatic hypermutation frequency J:303927
decreased autoantibody level J:303927
decreased IgA level J:303927
decreased IgE level J:303927
decreased IgG1 level J:303927
decreased IgG2b level J:303927
decreased IgG2c level J:303927
decreased IgG3 level J:303927
decreased IgG level J:303927
decreased IgM level J:303927
decreased plasma cell number J:303927
Hspb1tm1.1Jdn/Hspb1tm1.1Jdn
(B6.129S2(Cg)-Hspb1tm1.1Jdn)
abnormal chemokine secretion J:209117
abnormal macrophage physiology J:209117
abnormal neutrophil physiology J:209117
increased inflammatory response J:209117
increased interleukin-6 secretion J:209117
Hspb8em1(IMPC)J/Hspb8em1(IMPC)J
(C57BL/6NJ-Hspb8em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Hspb8tm1.1Depr/Hspb8tm1.1Depr
(B.129-Hspb8tm1.1Depr)
decreased circulating interleukin-6 level J:186292
Hspbap1tm1b(EUCOMM)Hmgu/Hspbap1tm1b(EUCOMM)Hmgu
(C57BL/6N-Hspbap1tm1b(EUCOMM)Hmgu/Bay)
increased spleen weight J:211773
Hspg2tm1Rdgr/Hspg2tm1Rdgr
(involves: 129S1/Sv * 129X1/SvJ)
abnormal osteoclast morphology J:121855
increased osteoclast cell number J:121855
osteoarthritis J:121855
Htr2ctm1Jul/Y
(B6.129S-Htr2ctm1Jul)
abnormal tumor necrosis factor level J:50262
Htr3atm1Ckn/Htr3atm1Ckn
(involves: 129S1/Sv * C57BL/6J * DBA/2)
decreased lymphocyte cell number J:90942
kidney inflammation J:90942
prostate gland inflammation J:90942
pyelonephritis J:90942
seminal vesiculitis J:90942
tubulointerstitial nephritis J:90942
Htra2mnd2/Htra2mnd2
(involves: C3H/HeJ * C57BL/6J * CAST/Ei)
abnormal thymus morphology J:12780
spleen atrophy J:12780
Htra2mnd2/Htra2mnd2
(B6.Cg-Htra2mnd2)
abnormal interleukin level J:76481
abnormal tumor necrosis factor level J:76481
Htra2mnd2/Htra2mnd2
(involves: C57BL/6J)
abnormal immune system morphology J:132627
decreased double-positive T cell number J:132627
decreased pre-B cell number J:132627
decreased pro-B cell number J:132627
decreased single-positive T cell number J:132627
Htra2tm1.1Hohj/Htra2tm1.1Hohj
Tg(Nes-cre)1Kln/0

(involves: C57BL/6J)
spleen atrophy J:225666
thymus atrophy J:225666
Htra2tm1.2Hohj/Htra2tm1.2Hohj
(involves: C57BL/6 * C57BL/6J)
decreased lymphocyte cell number J:225666
spleen atrophy J:225666
thymus atrophy J:225666
Htra2tm1Jdo/Htra2tm1Jdo
(involves: 129P/Ola * C57BL/6)
small spleen J:94227
small thymus J:94227
Htttm2Detl/Htt+
(B6J.129P2-Htttm2Detl)
microgliosis J:220868
hubb/hubb
(involves: ICR)
increased spleen weight J:8170
Hvcn1Gt(RRN293)Byg/Hvcn1Gt(RRN293)Byg
(B6.129P2-Hvcn1Gt(RRN293)Byg)
abnormal macrophage physiology J:148032
abnormal neutrophil physiology J:148032
hvlk/hvlk
(C57BL/6J-hvlk)
increased susceptibility to Herpesvirales infection J:105543
Hyal1tm1Stn/Hyal1tm1Stn
(involves: 129X1/SvJ * C57BL/6J)
osteoarthritis J:136860
Hyal2tm1.1Bfla/Hyal2tm1.1Bfla
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
increased spleen iron level J:146040
Hycc1em1(IMPC)Ccpcz/Hycc1em1(IMPC)Ccpcz
(C57BL/6N-Hycc1em1(IMPC)Ccpcz/Ccpcz)
enlarged thymus J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Hydinhyrh/Hydinhyrh
(involves: C57BL/6J * C57BL/10J * RIII)
rhinitis J:137815
thymus atrophy J:137815
Iapptm1Sgm/Iapp+
(involves: 129P2/OlaHsd)
increased osteoclast cell number J:88964
Iapptm1Sgm/Iapptm1Sgm
(involves: 129P2/OlaHsd)
increased osteoclast cell number J:88964
Ibdq1C57BL/6J/Ibdq1SAMP1/YitFcs
(involves: C57BL/6J * SAMP1/YitFc)
ileum inflammation J:84661
Ibdq1SAMP1/YitFcs/Ibdq1SAMP1/YitFcs
(involves: C57BL/6J * SAMP1/YitFc)
ileum inflammation J:84661
Ibdq2SAMP1/YitFcs/Ibdq2SAMP1/YitFcs
(involves: AKR/J * SAMP1/YitFcs)
small intestinal inflammation J:105411
Ibsptm1Jeau/Ibsptm1Jeau
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal osteoclast morphology J:228156, J:136223
decreased osteoclast cell number J:136223
increased osteoclast cell number J:228156
IbtkGt(XF224)Byg/IbtkGt(XF224)Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal splenocyte physiology J:174707
immune system phenotype J:174707
Ica1tm1b(EUCOMM)Wtsi/Ica1tm1b(EUCOMM)Wtsi
(C57BL/6N-Ica1tm1b(EUCOMM)Wtsi/Tcp)
abnormal spleen morphology J:211773
small spleen J:211773
Ica1tm1Mdos/Ica1tm1Mdos
(NOD.129-Ica1tm1Mdos)
abnormal T cell physiology J:83526
decreased susceptibility to autoimmune diabetes J:83526
Icam1tm1Alb/Icam1tm1Alb
(B6.Cg-Icam1tm1Alb)
abnormal leukocyte adhesion J:100242
abnormal leukocyte tethering or rolling J:100242
increased leukocyte cell number J:100242
increased neutrophil cell number J:100242
Icam1tm1Bay/Icam1tm1Bay
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal cellular extravasation J:14565
abnormal immune system physiology J:14565
decreased susceptibility to type IV hypersensitivity reaction J:14565
increased neutrophil cell number J:14565
Icam1tm1Bay/Icam1tm1Bay
(B6.129S7-Icam1tm1Bay)
abnormal cellular extravasation J:48271
abnormal leukocyte migration J:24239
abnormal leukocyte tethering or rolling J:48271
decreased susceptibility to endotoxin shock J:123460
increased eosinophil cell number J:48271
increased lymphocyte cell number J:48271
increased monocyte cell number J:48271
increased neutrophil cell number J:48271, J:24239
Icam1tm1Bay/Icam1tm1Bay
(either: B6.129S7-Icam1tm1Bay or (involves: 129S7/SvEvBrd * C57BL/6))
abnormal leukocyte tethering or rolling J:31374
increased leukocyte cell number J:31374
Icam1tm1Bay/Icam1tm1Bay
(B6.129S7-Icam1tm1Bay/J)
decreased susceptibility to parasitic infection induced morbidity/mortality J:193592
immune system phenotype J:193592
Icam1tm1Bay/Icam1tm1Bay
(involves: 129S7/SvEvBrd * C57BL/6)
decreased susceptibility to induced colitis J:111227
impaired neutrophil recruitment J:112286
increased neutrophil cell number J:112286
large intestinal inflammation J:111227
Icam1tm1Bay/Icam1tm1Bay
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay

(involves: 129S7/SvEvBrd * C57BL/6)
decreased acute inflammation J:112286
impaired neutrophil chemotaxis J:112286
increased neutrophil cell number J:112286
Icam1tm1Bay/Icam1tm1Bay
Selltm1Tft/Selltm1Tft

(B6.129-Selltm1Tft Icam1tm1Bay)
abnormal cellular extravasation J:48271
abnormal inflammatory response J:124291
abnormal leukocyte tethering or rolling J:48271
abnormal macrophage physiology J:124291
abnormal mast cell physiology J:124291
impaired macrophage chemotaxis J:124291
increased eosinophil cell number J:48271
increased lymphocyte cell number J:48271
increased monocyte cell number J:48271
increased neutrophil cell number J:48271
Icam1tm1Bay/Icam1tm1Bay
Selptm1Bay/Selptm1Bay

(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal leukocyte migration J:24239
increased neutrophil cell number J:24239
Icam1tm1Bay/Icam1tm1Bay
Selptm1Bay/Selptm1Bay

(either: B6.129S7-Selptm1Bay Icam1tm1Bay or (involves: 129S7/SvEvBrd * C57BL/6))
impaired leukocyte tethering or rolling J:31374
Icam1tm1Bay/Icam1tm1Bay
Selptm1Bay/Selptm1Bay

(B6.129S7-Icam1tm1Bay Selptm1Bay/J)
immune system phenotype J:119906
Icam1tm1Cws/Icam1tm1Cws
(involves: C57BL/6)
abnormal macrophage morphology J:100353
Icam1tm1Jcgr/Icam1tm1Jcgr
(involves: 129S4/SvJae * C57BL/6 * DBA/2)
abnormal interleukin level J:18743
abnormal T cell physiology J:18743
abnormal tumor necrosis factor level J:18743
decreased susceptibility to bacterial infection induced morbidity/mortality J:18743
decreased susceptibility to type IV hypersensitivity reaction J:18743
increased lymphocyte cell number J:18743
increased neutrophil cell number J:18743
Icam1tm1Jcgr/Icam1tm1Jcgr
(B6.129S4-Icam1tm1Jcgr)
immune system phenotype J:113463
Icam1tm1Jcgr/Icam1tm1Jcgr
Ldlrtm1Her/Ldlrtm1Her

(involves: 129S4/SvJae * 129S7/SvEvBrd)
increased neutrophil cell number J:69597
Icam1tm1Jcgr/Icam1tm1Jcgr
Ldlrtm1Her/Ldlrtm1Her
Vcam1tm1Dmil/Vcam1tm1Dmil

(involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6)
increased leukocyte cell number J:69597
increased lymphocyte cell number J:69597
increased monocyte cell number J:69597
increased neutrophil cell number J:69597
Icam1tm1Jcgr/Icam1tm1Jcgr
Tg(INS-Il10)#Sar/0

(NOD.Cg-Icam1tm1Jcgr Tg(INS-Il10)#Sar)
decreased susceptibility to autoimmune diabetes J:66103
periinsulitis J:66103
Icam1tm1Jcgr/Icam1tm1Jcgr
Vcam1tm1Dmil/Vcam1tm1Dmil

(involves: 129S4/SvJae * C57BL/6)
impaired macrophage chemotaxis J:227109
Icam2tm1Jcgr/Icam2tm1Jcgr
(involves: 129S4/SvJae * C57BL/6)
abnormal eosinophil physiology J:54748
IchsC57BL/6J/IchsC57BL/6J
(involves: A/J * C57BL/6J * C57BL/6JOlaHsd)
abnormal type I hypersensitivity reaction J:63737
IchsC57BL/6JOlaHsd/IchsC57BL/6JOlaHsd
(involves: A/J * C57BL/6J * C57BL/6JOlaHsd)
abnormal type I hypersensitivity reaction J:63737
Icostm1.1Wks/Icostm1.1Wks
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal B cell number J:155586
abnormal B cell physiology J:155586
abnormal B cell selection J:155586
abnormal class switch recombination J:155586
abnormal immune system physiology J:155586
abnormal Peyer's patch germinal center morphology J:155586
abnormal spleen morphology J:155586
decreased CD4-positive, alpha-beta T cell number J:155586
decreased IgA level J:155586
decreased IgG1 level J:155586
decreased IgG2b level J:155586
decreased IgG2c level J:155586
decreased interleukin-4 secretion J:155586
decreased interleukin-21 secretion J:155586
decreased spleen germinal center number J:155586
small Peyer's patches J:155586
Icostm1Dgry/Icostm1Dgry
(B6.129P2-Icostm1Dgry)
abnormal CD4-positive, alpha-beta T cell physiology J:123477
abnormal immune system physiology J:123477
abnormal interleukin secretion J:123477
abnormal leukocyte cell number J:123477
abnormal memory B cell number J:123477
abnormal response to infection J:123477
abnormal T cell physiology J:123477
decreased germinal center B cell number J:123477
decreased IgG level J:123477
decreased interleukin-4 secretion J:123477
decreased interleukin-5 secretion J:123477
decreased plasma cell number J:123477
increased plasma cell number J:123477
Icostm1Flv/Icos+
(NOD.129S1-Icostm1Flv)
insulitis J:131529
Icostm1Flv/Icostm1Flv
(involves: 129/Sv * C57BL/6)
abnormal immunoglobulin level J:87123
abnormal interferon level J:87123
abnormal interleukin level J:87123
abnormal T-helper 2 physiology J:87123
decreased IgE level J:87123
decreased IgG1 level J:87123
immune system phenotype J:87123
increased susceptibility to experimental autoimmune encephalomyelitis J:87123
small lymph nodes J:87123
Icostm1Flv/Icostm1Flv
(NOD.129S1-Icostm1Flv)
decreased anti-insulin autoantibody level J:131529
decreased autoantibody level J:131529
decreased IgG level J:131529
decreased interferon-gamma secretion J:131529
decreased susceptibility to autoimmune diabetes J:131529
decreased T cell number J:131529
immune system phenotype J:131529
insulitis J:131529
Icostm1Flv/Icostm1Flv
(involves: 129S1/Sv)
abnormal cytokine secretion J:112600
Icostm1Flv/Icostm1Flv
Tg(Cd4-Maf)6666Glm/0

(involves: 129S1/Sv * C57BL/6)
abnormal cytokine secretion J:112600
Icostm1Flv/Icostm1Flv
Tg(TcraTcrb)425Cbn/0

(involves: 129S1/Sv * C57BL/6)
abnormal cytokine secretion J:112600
Icostm1Mak/Icostm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell number J:155586
abnormal B cell physiology J:66702
abnormal class switch recombination J:66702
abnormal immune system physiology J:66702
abnormal Peyer's patch germinal center morphology J:155586
abnormal spleen morphology J:66702
abnormal T cell physiology J:66702
decreased CD4-positive, alpha-beta T cell number J:155586
decreased IgA level J:155586
decreased IgE level J:66702
decreased IgG1 level J:66702, J:155586
decreased IgG2b level J:155586
decreased IgG2c level J:155586
decreased interleukin-21 secretion J:155586
decreased spleen germinal center number J:66702, J:155586
decreased spleen germinal center size J:66702
decreased T cell proliferation J:66702
small Peyer's patches J:155586
Icostm1Shr/Icostm1Shr
(Not Specified)
abnormal CD4-positive, alpha-beta T cell physiology J:87124
abnormal immunoglobulin level J:87124
abnormal interleukin level J:87124
abnormal spleen germinal center morphology J:87124
abnormal T cell differentiation J:87124
decreased IgE level J:87124
decreased IgG1 level J:87124
decreased IgG2a level J:87124
decreased IgG level J:87124
increased IgG3 level J:87124
Icostm1Tkan/Icostm1Tkan
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal NK cell physiology J:95353
abnormal Peyer's patch germinal center morphology J:95728
decreased circulating interferon-gamma level J:95353
decreased circulating interleukin-4 level J:95353
small Peyer's patches J:95728
Icosltm1Cdon/Icosltm1Cdon
(involves: 129S6/SvEvTac)
abnormal immunoglobulin level J:86697
abnormal interferon level J:86697
abnormal interleukin secretion J:86697
abnormal T cell differentiation J:86697
abnormal T-helper 2 physiology J:86697
decreased IgE level J:86697
decreased IgG1 level J:86697
decreased IgG2a level J:86697
decreased IgG level J:86697
decreased IgM level J:86697
small spleen J:86697
Icosltm1Kplm/Icosltm1Kplm
(involves: 129P2/OlaHsd)
abnormal humoral immune response J:84893
abnormal immune serum protein physiology J:84893
abnormal spleen germinal center morphology J:84893
decreased IgA level J:84893
decreased IgG2a level J:84893
decreased IgG2b level J:84893
decreased interleukin-4 secretion J:84893
decreased interleukin-10 secretion J:84893
increased interferon-gamma secretion J:84893
Icosltm1Mak/Icosltm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:84668
abnormal immune system physiology J:84668
abnormal spleen morphology J:84668
abnormal T-helper 2 cell differentiation J:84668
decreased IgG1 level J:84668
decreased inflammatory response J:84668
decreased spleen germinal center number J:84668
decreased spleen germinal center size J:84668
immune system phenotype J:84668
Id1tm1Zhu/Id1+
Id3tm1Zhu/Id3tm1Zhu

(involves: 129S1/Sv * 129S4/SvJaeSor)
increased susceptibility to otitis media J:311050
Id1tm1Zhu/Id1tm1Zhu
(involves: 129S1/Sv * C57BL/6)
abnormal myelopoiesis J:155384
abnormal osteoclast differentiation J:155384
decreased lymphocyte cell number J:119519
increased monocyte cell number J:155384
increased neutrophil cell number J:155384
increased osteoclast cell number J:155384
myeloid hyperplasia J:155384
Id1tm1Zhu/Id1tm1Zhu
Id3tm1Zhu/Id3+

(involves: 129S1/Sv * 129S4/SvJaeSor)
increased susceptibility to otitis media J:311050
Id1tm1Zhu/Id1tm1Zhu
Tcf3tm1Wein/Tcf3tm1Wein

(involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
abnormal thymus corticomedullary boundary morphology J:44278
absent B cells J:44278
arrested B cell differentiation J:44278
decreased lymphocyte cell number J:44278
intermingled spleen red and white pulp J:44278
Id2tm1Ago/Id2tm1Ago
(B6.129-Id2tm1Ago)
absent lymph nodes J:116119
absent NK cells J:116119
decreased CD8-positive, alpha-beta T cell number J:116119
Id2tm1Ago/Id2tm1Ago
Tg(TcraTcrb)1100Mjb/0

(B6.Cg-Id2tm1Ago Tg(TcraTcrb)1100Mjb)
abnormal T cell activation J:116119
Id2tm1Gtbz/Id2tm1Gtbz
Nfil3tm1.1Brad/Nfil3tm1.1Brad

(involves: C57BL/6)
immune system phenotype J:194760
Id2tm1Mais/Id2tm1Mais
(involves: 129X1/SvJ * C57BL/6)
abnormal immune system physiology J:146624
Id2tm1Yyk/Id2tm1Yyk
(involves: 129S1/Sv * 129X1/SvJ)
abnormal oropharyngeal lymphoid tissue morphology J:78101
absent Peyer's patches J:53267
decreased lymph node number J:53267
decreased NK cell number J:53267
Id2tm1Yyk/Id2tm1Yyk
(involves: 129S1/Sv * 129X1/SvJ * NMRI)
abnormal oropharyngeal lymphoid tissue morphology J:78101
absent Peyer's patches J:53267
decreased lymph node number J:53267
decreased NK cell number J:53267
Id2tm1Yyk/Id2tm1Yyk
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * FVB/NJ))
absent lymph nodes J:125739
absent Peyer's patches J:125739
decreased NK T cell number J:125739
Id2tm1Yyk/Id2tm1Yyk
Rorctm2Litt/Rorc+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
abnormal gut-associated lymphoid tissue morphology J:87395
abnormal immune system cell morphology J:87395
abnormal lymph organ development J:87395
Id2tm1Yyk/Id2tm1Yyk
Tcf3tm1Cmu/Tcf3+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
absent axillary lymph nodes J:125739
absent brachial lymph nodes J:125739
absent inguinal lymph nodes J:125739
decreased NK T cell number J:125739
Id2tm1Yyk/Id2tm1Yyk
Tcf3tm1Cmu/Tcf3tm1Cmu

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
decreased B cell number J:125739
decreased NK T cell number J:125739
immune system phenotype J:125739
small lymph nodes J:125739
Id2tm2.1Ago/Id2+
Id3tm2.1Cmu/Id3+

(involves: C57BL/6)
immune system phenotype J:179006
Id2tm2.1Gtbz/Id2tm2.1Gtbz
Tg(Itgax-cre)1-1Reiz/0

(involves: C57BL/6 * CBA)
immune system phenotype J:194760
Id3em1(IMPC)Mbp/Id3em1(IMPC)Mbp
(C57BL/6N-Id3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Id3tm1Cmu/Id3tm1Cmu
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal double-positive T cell morphology J:59969
abnormal T cell differentiation J:59969
Id3tm1Zhu/Id3tm1Zhu
(involves: 129/Sv * C57BL/6)
abnormal T cell physiology J:56950
decreased B cell proliferation J:56950
decreased immunoglobulin level J:56950
immune system phenotype J:56950
Id3tm1Zhu/Id3tm1Zhu
(involves: 129S4/SvJaeSor * C57BL/6)
abnormal T cell differentiation J:144696
Id3tm1Zhu/Id3tm1Zhu
(involves: 129S4/SvJaeSor)
immune system phenotype J:93916
increased autoantibody level J:93916
lacrimal gland inflammation J:93916
salivary gland inflammation J:93916
Id3tm2.1Cmu/Id3tm2.1Cmu
(Not Specified)
decreased thymocyte number J:176462
increased B cell number J:176462
increased gamma-delta T cell number J:176462
increased T follicular helper cell number J:176462
Id3tm2.1Cmu/Id3tm2.1Cmu
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJaeSor * C57BL/6 * DBA/2)
decreased thymocyte number J:176462
immune system phenotype J:176462
Id3tm2.1Zhu/Id3tm2.1Zhu
Tg(Lck-cre)#Zhu/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL * SJL/J)
abnormal T cell differentiation J:172701
decreased CD4-positive, alpha-beta T cell number J:172701
decreased CD8-positive, alpha-beta T cell number J:172701
decreased T cell number J:172701
increased CD4-positive, alpha-beta memory T cell number J:172701
increased CD8-positive, alpha-beta memory T cell number J:172701
increased gamma-delta T cell number J:172701
parotid gland inflammation J:172701
submandibular gland inflammation J:172701
Idc/Idc+
(involves: 101 * C3H)
blepharitis J:6686
Idd1NOD/Uf/Idd1NOD/Uf
(involves: C57BL/6 * NOD/Uf)
periinsulitis J:33172
Idd1NOD/Uf/Idd1NOD/Uf
(B6.NOD-(D17Mit164-D17Mit152))
increased CD4-positive, alpha-beta T cell number J:92304
Idd2NOD/Smrf/Idd2NOD/Smrf
(involves: NON/Lt * NOD/Smrf)
increased CD4-positive, alpha-beta T cell number J:30526
Idd3A/J/Idd3A/J
(NOD.A-Idd3A/J)
increased susceptibility to autoimmune diabetes J:120349
Idd3C57BL/6/Idd3C57BL/6
(NOD.B6-Idd3C57BL/6)
decreased susceptibility to autoimmune diabetes J:120349
Idd3C57BL/10SnJ/Idd3C57BL/10SnJ
Idd5.2C57BL/10SnJ/Idd5.2C57BL/10SnJ

(involves: C57BL/10SnJ * NOD/MrkTac)
insulitis J:143549
Idd3C57BL/10SnJ/Idd3C57BL/10SnJ
Idd5C57BL/10SnJ/Idd5C57BL/10SnJ

(involves: C57BL/10 * NOD/MrkTac)
pancreas inflammation J:88667
Idd3CAST/EiJ/Idd3CAST/EiJ
(NOD.CAST-Idd3CAST/EiJ)
increased susceptibility to autoimmune diabetes J:120349
Idd3CZECHI/EiJ/Idd3CZECHI/EiJ
(NOD.CZECH-Idd3CZECHI/EiJ)
decreased susceptibility to autoimmune diabetes J:120349
Idd3NOD/?
(involves: C57BL/10 * NOD)
pancreas inflammation J:17906
Idd3SWR/J/Idd3SWR/J
(NOD.SWR-Idd3SWR/J)
increased susceptibility to autoimmune diabetes J:120349
Idd4.3C57L/Idd4.3C57L
(involves: C57L/J * NOD)
abnormal cytokine secretion J:118951
abnormal macrophage physiology J:118951
increased susceptibility to autoimmune diabetes J:118951
Idd4C57BL/6/Idd4C57BL/6
(involves: C57BL/6 * DBA/2)
increased T cell proliferation J:25969
Idd4C57BL/6/Idd4C57BL/6
(involves: C57BL/6 * NOD)
increased T cell proliferation J:25969
Idd4C57BL/6J/?
(involves: C57BL/6J * NOD)
pancreas inflammation J:73763
Idd4NOD/Jsd/?
(involves: NOD/Jsd * NOR/LtJ)
pancreas inflammation J:99002
Idd4NOD/Jsd/Idd4NOD/Jsd
Idd9NOD/Jsd/Idd9NOD/Jsd

(involves: NOD/Jsd * NOR/LtJ)
pancreas inflammation J:99002
Idd4NOD/Idd4NOD
(B6.NOD-Idd4)
abnormal cytokine secretion J:85823
decreased NK T cell number J:85823
Idd4NOR/LtJ/?
(involves: NOD/Jsd * NOR/LtJ)
pancreas inflammation J:99002
Idd5NOD/Uf/Idd5NOD/Uf
(involves: C57BL/6 * NOD/Uf)
periinsulitis J:33172
Idd6.1C3H/HeJ/Idd6.1C3H/HeJ
(involves: C3H/HeJ * NOD)
decreased susceptibility to autoimmune diabetes J:115021
Idd6.2C3H/HeJ/Idd6.2C3H/HeJ
(involves: C3H/HeJ * NOD)
decreased susceptibility to autoimmune diabetes J:115021
Idd6.2C3H/HeJ/Idd6.2C3H/HeJ
(NOD.C3-Idd6.2C3H/HeJ)
decreased NK cell number J:137837
Idd6.2NOD/Idd6.2NOD
(B6.NOD-(D6Mit259-D6Mit304))
abnormal T cell differentiation J:120148
Idd6.3C3H/HeJ/Idd6.3C3H/HeJ
(involves: C3H/HeJ * NOD)
decreased susceptibility to autoimmune diabetes J:115021
Idd6C3H/HeJ/Idd6C3H/HeJ
(NOD.C3-Idd6C3H/HeJ)
decreased interferon-gamma secretion J:137837
decreased interleukin-4 secretion J:137837
decreased NK cell number J:137837
Idd6C57BL/6/Idd6NOD
(involves: C57BL/6 * NOD)
decreased T cell proliferation J:72360
Idd6NOD/Idd6NOD
(involves: C57BL/6 * NOD)
decreased T cell proliferation J:72360
Idd6NOD/Idd6NOD
(B6.NOD-Idd6)
abnormal NK cell physiology J:85823
Idd7NOD/ShiLt/Idd7NOD/ShiLt
(involves: C57BL/6 * NOD/ShiLt)
abnormal T cell clonal deletion J:131557
Idd9.1C57BL/10SnJ/Idd9.1C57BL/10SnJ
(NOD.B10-Idd9.1C57BL/10SnJ)
increased NK T cell number J:85823
Idd9NOD/Jsd/?
(involves: NOD/Jsd * NOR/LtJ)
pancreas inflammation J:99002
Idd9NOR/LtJ/?
(involves: NOD/Jsd * NOR/LtJ)
pancreas inflammation J:99002
Idd10NOD/ShiLt/Idd10NOD/ShiLt
Idd3NOD/Idd3NOD

(B6.NOD-Idd3NOD Idd10NOD/Lt)
abnormal cytokine secretion J:85823
abnormal NK T cell physiology J:85823
Idd13NOD/ShiLt/Idd13NOD/ShiLt
(B6.NOD-Idd13)
abnormal cytokine secretion J:85823
abnormal NK T cell physiology J:85823
Idd16.1ALR/LtJ/Idd16.1ALR/LtJ
(involves: ALR/LtJ * NOD/LtJ)
pancreas inflammation J:98187
Idh1tm1Mak/Idh1tm1Mak
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:186700
decreased B cell number J:186700
decreased CD4-positive, alpha-beta T cell number J:186700
decreased CD8-positive, alpha-beta T cell number J:186700
enlarged spleen J:186700
increased CD4-positive, alpha-beta T cell number J:186700
Idh1tm2Mak/Idh1tm2Mak
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:186700
decreased B cell number J:186700
decreased CD4-positive, alpha-beta T cell number J:186700
decreased CD8-positive, alpha-beta T cell number J:186700
enlarged spleen J:186700
increased CD4-positive, alpha-beta T cell number J:186700
Idh2tm1Jwpk/Idh2tm1Jwpk
(involves: 129S4/SvJae * C57BL/6)
increased osteoclast cell number J:272241
Idh3gem1(IMPC)Bay/Idh3gem1(IMPC)Bay
(C57BL/6N-Idh3gem1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Ido1tm1Alm/Ido1tm1Alm
(involves: 129X1/SvJ * C57BL/6 * CBA)
abnormal cytokine secretion J:120813
abnormal dendritic cell physiology J:120813
Ido1tm1Alm/Ido1tm1Alm
(involves: 129X1/SvJ * BALB/c)
abnormal cytokine level J:170565
decreased leukocyte cell number J:170565
epididymis inflammation J:170565
Ido1tm1Alm/Ido1tm1Alm
(involves: 129X1/SvJ * C57BL/6J * FVB/N)
decreased susceptibility to type IV hypersensitivity reaction J:211949
increased interferon-gamma secretion J:211949
increased interleukin-6 secretion J:211949
increased tumor necrosis factor secretion J:211949
Ido1tm1Alm/Ido1tm1Alm
(involves: 129X1/SvJ * C57BL/6J)
abnormal macrophage morphology J:282516
abnormal macrophage physiology J:282516
Ido2em1Lamn/Ido2em1Lamn
(involves: BALB/c * C57BL/6J)
decreased susceptibility to type IV hypersensitivity reaction J:342726
Ido2em1Lamn/Ido2em1Lamn
Tg(TcraR28,TcrbR28)KRNDim/0

(involves: C57BL/6 * C57BL/6J * SJL)
arthritis J:342726
Ido2em2Lamn/Ido2em2Lamn
(involves: BALB/c * C57BL/6J)
decreased susceptibility to type IV hypersensitivity reaction J:342726
Ido2em2Lamn/Ido2em2Lamn
Tg(TcraR28,TcrbR28)KRNDim/0

(involves: C57BL/6 * C57BL/6J * SJL)
arthritis J:342726
Ido2tm1.2Gcp/Ido2tm1.2Gcp
(involves: C57BL/6J * FVB/N)
abnormal chemokine secretion J:211949
abnormal regulatory T cell physiology J:211949
decreased interferon-gamma secretion J:211949
decreased interleukin-6 secretion J:211949
decreased susceptibility to type IV hypersensitivity reaction J:211949
decreased tumor necrosis factor secretion J:211949
Idstm1Muen/Y
(Not Specified)
abnormal lymph node morphology J:108761
Idstm1Muen/Y
(involves: C57BL/6)
increased spleen weight J:259752
Iduatm1Efn/Iduatm1Efn
(involves: C57BL/6)
abnormal microglial cell morphology J:81974
abnormal microglial cell physiology J:81974
increased susceptibility to otitis media J:123676
Ier3tm1Mxw/Ier3tm1Mxw
(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:157504
abnormal interleukin level J:157504
abnormal macrophage physiology J:157504
abnormal response to infection J:157504
abnormal tumor necrosis factor level J:157504
abnormal tumor necrosis factor secretion J:157504
decreased regulatory T cell number J:157504
impaired macrophage phagocytosis J:157504
increased granulocyte number J:157504
increased neutrophil cell number J:157504
increased susceptibility to parasitic infection J:157504
Ier3tm1Mxw/Ier3tm1Mxw
(involves: C57BL/6)
decreased susceptibility to induced colitis J:194587
increased T-helper 17 cell number J:194587
Ier3tm1Mxw/Ier3tm1Mxw
Rag1tm1Mom/Rag1tm1Mom

(involves: 129S7/SvEvBrd * C57BL/6)
decreased susceptibility to induced colitis J:194587
If1l/If1l
(involves: BALB/c)
abnormal circulating interferon level J:5113
abnormal response to infection J:38004
If1l/If1l
(B6.C-Ifi44lH28-c If1l/(HW81)aByJ)
abnormal response to infection J:38004
Ifi27l2atm1(KOMP)Vlcg/Ifi27l2atm1(KOMP)Vlcg
(involves: C57BL/6NTac)
immune system phenotype J:221531
Ifi30tm1Cres/Ifi30tm1Cres
(involves: 129S1/Sv * C57BL/6)
abnormal professional antigen presenting cell physiology J:72708
Ifi35em1Hhl/Ifi35em1Hhl
(C57BL/6-Ifi35em1Hhl)
decreased circulating interleukin-6 level J:298909
decreased circulating tumor necrosis factor level J:298909
decreased susceptibility to bacterial infection induced morbidity/mortality J:298909
decreased susceptibility to endotoxin shock J:298909
Ifi44tm1b(KOMP)Wtsi/Ifi44tm1b(KOMP)Wtsi
(C57BL/6N-Ifi44tm1b(KOMP)Wtsi/Tcp)
enlarged lymph nodes J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Ifi44tm1b(KOMP)Wtsi/Ifi44tm1b(KOMP)Wtsi
(involves: C57BL/6N)
decreased CXCL10 secretion J:297991
decreased interleukin-1 beta secretion J:297991
increased CD8-positive, alpha-beta T cell number J:297991
increased susceptibility to Riboviria infection J:297991
Ifi47tm1Gat/Ifi47tm1Gat
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:87535
increased susceptibility to parasitic infection J:87535
Ifi204tm1.1Cjul/Ifi204tm1.1Cjul
(B6.129(Cg)-Ifi204tm1.1Cjul)
decreased circulating interferon-beta level J:270123
decreased circulating interleukin-1 beta level J:270123
decreased circulating interleukin-6 level J:270123
decreased circulating tumor necrosis factor level J:270123
decreased interferon-beta secretion J:270123
decreased interleukin-6 secretion J:270123
decreased susceptibility to endotoxin shock J:270123
decreased tumor necrosis factor secretion J:270123
Ifi208em1(IMPC)Mbp/Ifi208em1(IMPC)Mbp
(C57BL/6N-Ifi208em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Ifih1Rgsc422/Ifih1+
(D2JJcl.B6JJcl-Ifih1Rgsc422)
abnormal chemokine level J:209917
abnormal cytokine level J:209917
abnormal dendritic cell antigen presentation J:209917
abnormal leukocyte cell number J:209917
abnormal macrophage activation involved in immune response J:209917
abnormal T cell activation J:209917
autoimmune response J:209917
chronic liver inflammation J:209917
glomerulonephritis J:209917
increased anti-double stranded DNA antibody level J:209917
increased anti-nuclear antigen antibody level J:209917
increased dendritic cell number J:209917
increased granulocyte number J:209917
increased IgA level J:209917
increased IgG level J:209917
increased IgM level J:209917
increased immunoglobulin level J:209917
increased inflammatory response J:209917
increased macrophage cell number J:209917
increased plasma cell number J:209917
increased susceptibility to systemic lupus erythematosus J:209917
skin inflammation J:209917
Ifih1Rgsc422/Ifih1+
Ifnar1tm1Agt/Ifnar1+

(involves: 129S2/SvPas * C57BL/6JJcl * DBA/2JJcl)
glomerulonephritis J:209917
Ifih1Rgsc422/Ifih1+
Mavstm1Aki/Mavs+

(involves: C57BL/6JJcl * DBA/2JJcl)
glomerulonephritis J:209917
Ifih1Rgsc422/Ifih1+
Mavstm1Aki/Mavstm1Aki

(involves: C57BL/6JJcl * DBA/2JJcl)
immune system phenotype J:209917
Ifih1Rgsc422/Ifih1Rgsc422
(D2JJcl.B6JJcl-Ifih1Rgsc422)
glomerulonephritis J:209917
increased susceptibility to systemic lupus erythematosus J:209917
Ifih1tm1.1Cln/Ifih1tm1.1Cln
(involves: 129X1/SvJ * C57BL/6)
abnormal cytokine secretion J:110201
decreased interferon-alpha secretion J:110201
decreased interleukin-6 secretion J:110201
increased susceptibility to Picornaviridae infection J:110201
Ifih1tm1.1Cln/Ifih1tm1.1Cln
(involves: 129X1/SvJ)
decreased interferon-beta secretion J:240099
Ifih1tm1Aki/Ifih1tm1Aki
(involves: 129/Sv * C57BL/6)
abnormal dendritic cell physiology J:137522
abnormal interferon level J:137522
abnormal interleukin level J:137522
increased susceptibility to Picornaviridae infection J:137522
Ifih1tm1Aki/Ifih1tm1Aki
Ticam1tm1Aki/Ticam1tm1Aki

(involves: 129P2/OlaHsd)
abnormal interferon level J:137522
abnormal interleukin level J:137522
Ifit1tm1(KOMP)Vlcg/Ifit1tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
increased susceptibility to Riboviria infection J:187549
increased susceptibility to Riboviria infection induced morbidity/mortality J:187549
Ifit1tm1(KOMP)Vlcg/Ifit1tm1(KOMP)Vlcg
(involves: C57BL/6 * C57BL/6NTac)
abnormal interferon level J:205203
abnormal T cell physiology J:205203
brain inflammation J:205203
increased susceptibility to Coronaviridae infection J:205203
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:205203
Ifit2tm1.1Ebsb/Ifit2tm1.1Ebsb
(B6NCrl.129P2(C)-Ifit2tm1.1Ebsb)
decreased circulating interleukin-1 beta level J:199862
decreased circulating interleukin-6 level J:199862
decreased circulating interleukin-12b level J:199862
decreased circulating tumor necrosis factor level J:199862
decreased interleukin-6 secretion J:199862
decreased tumor necrosis factor secretion J:199862
increased susceptibility to bacterial infection induced morbidity/mortality J:199862
Ifit2tm1.1Ebsb/Ifit2tm1.1Ebsb
(B6.129P2(C)-Ifit2tm1.1Ebsb)
enhanced humoral immune response J:233986
increased IgE level J:233986
increased IgG1 level J:233986
increased IgG3 level J:233986
increased IgM level J:233986
Ifit2tm1.1Tac/Ifit2+
(involves: C57BL/6)
increased susceptibility to Riboviria infection induced morbidity/mortality J:195382
Ifit2tm1.1Tac/Ifit2tm1.1Tac
(involves: C57BL/6)
increased susceptibility to Riboviria infection J:195382
increased susceptibility to Riboviria infection induced morbidity/mortality J:195382
Ifitm1tm1.1Ieg/Ifitm1tm1.1Ieg
(B6.129P2-Ifitm1tm1.1Ieg)
decreased granulocyte number J:192287
decreased T cell number J:192287
immune system phenotype J:192287
increased IgE level J:192287
Ifitm3tm1Masu/Ifitm3tm1Masu
(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to Orthomyxoviridae infection J:183865
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:183865
increased susceptibility to Riboviria infection J:209781
Ifitm5em1Pmof/Ifitm5+
(involves: CD-1)
abnormal osteoclast morphology J:255349
Ifna6tm1Aki/Ifna6+
Myd88tm1Aki/Myd88tm1Aki

(involves: 129P2/OlaHsd)
abnormal plasmacytoid dendritic cell morphology J:124340
decreased interferon-alpha secretion J:124340
Ifnar1m1Btlr/Ifnar1m1Btlr
(C57BL/6J-Ifnar1m1Btlr)
abnormal macrophage physiology J:142790
decreased interferon-alpha secretion J:142790
decreased interferon-beta secretion J:142790
immune system phenotype J:142790
increased susceptibility to Adenoviridae infection J:142790
increased susceptibility to Herpesvirales infection J:142790
increased susceptibility to Orthomyxoviridae infection J:142790
increased susceptibility to Riboviria infection J:142790
Ifnar1m2Btlr/Ifnar1m2Btlr
(involves: C57BL/6J)
decreased interferon-beta secretion J:198556
Ifnar1tm1Agt/Ifnar1tm1Agt
(involves: 129S2/SvPas)
abnormal cytokine secretion J:114555
abnormal dendritic cell physiology J:114555
abnormal immunoglobulin level J:101427
abnormal inflammatory response J:114555
abnormal NK cell physiology J:79552, J:139001
immune system phenotype J:286237
impaired natural killer cell mediated cytotoxicity J:79552
increased susceptibility to Coronaviridae infection J:144400
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:144400
increased susceptibility to Herpesvirales infection J:197569, J:81243
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:115139
increased susceptibility to Paramyxoviridae infection J:160878
increased susceptibility to Paramyxoviridae infection induced morbidity/mortality J:160878
increased susceptibility to Picornaviridae infection J:137522
increased susceptibility to Poxviridae infection J:101427
Ifnar1tm1Agt/Ifnar1tm1Agt
(involves: 129S2/SvPas * C57BL/6)
abnormal susceptibility to infection J:120938
immune system phenotype J:238323
Ifnar1tm1Agt/Ifnar1tm1Agt
(B6.129S2-Ifnar1tm1Agt)
abnormal osteoclast morphology J:76097
abnormal response to infection J:116703
decreased interferon-alpha secretion J:125611
decreased interferon-beta secretion J:125611
decreased interleukin-6 secretion J:199862
decreased tumor necrosis factor secretion J:199862
impaired natural killer cell mediated cytotoxicity J:118750
increased susceptibility to bacterial infection induced morbidity/mortality J:199862
Ifnar1tm1Agt/Ifnar1tm1Agt
(involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL)
increased susceptibility to Orthomyxoviridae infection J:119783
Ifnar1tm1Agt/Ifnar1tm1Agt
(involves: 129S2/SvPas * 129S6/SvEvTac)
abnormal CD8-positive, alpha-beta T cell physiology J:54482
abnormal interferon-gamma secretion J:54482
increased circulating interleukin-12 level J:54482
increased susceptibility to Riboviria infection J:54482
Ifnar1tm1Agt/Ifnar1tm1Agt
(involves: 129S2/SvPas * BALB/c)
abnormal cytokine level J:291874
abnormal mononuclear phagocyte morphology J:291874
decreased Ly6C high monocyte number J:291874
decreased susceptibility to Coronaviridae infection J:291874
decreased T cell apoptosis J:291874
increased CD4-positive, alpha-beta T cell number J:291874
increased CD8-positive, alpha-beta T cell number J:291874
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:291874
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:291874
Ifnar1tm1Agt/Ifnar1tm1Agt
Ifngr1tm1Agt/Ifngr1tm1Agt

(involves: 129S2/SvPas * 129S7/SvEvBrd)
abnormal immunoglobulin level J:101427
immune system phenotype J:286237
increased susceptibility to Herpesvirales infection J:81243
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:115139
increased susceptibility to Poxviridae infection J:101427
increased susceptibility to Togaviridae infection J:81243
Ifnar1tm1Agt/Ifnar1tm1Agt
Myd88tm1Aki/Myd88+

(B6.129-Myd88tm1Aki Ifnar1tm1Agt)
increased susceptibility to parasitic infection J:140485
Ifnar1tm1Agt/Ifnar1tm1Agt
Myd88tm1Aki/Myd88tm1Aki

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal leukocyte migration J:171379
Ifnar1tm1Agt/Ifnar1tm1Agt
Myd88tm1Aki/Myd88tm1Aki

(B6.129-Myd88tm1Aki Ifnar1tm1Agt)
increased susceptibility to parasitic infection J:140485
increased susceptibility to parasitic infection induced morbidity/mortality J:140485
Ifnar1tm1Agt/Ifnar1tm1Agt
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0

(involves: 129S2/SvPas * C57BL/6 * C57BL/6N * DBA/2)
dermatitis J:312394
immune system phenotype J:312394
Ifnar1tm1Agt/Ifnar1tm1Agt
Slamf1tm1Oono/Slamf1tm1Oono

(B6.129-Slamf1tm1Oono Ifnar1tm1Agt)
abnormal lymphopoiesis J:117810
increased susceptibility to Paramyxoviridae infection J:117810
Ifnar1tm1Agt/Ifnar1tm1Agt
Sp140em1Vnce/Sp140em1Vnce

(B6.Cg-Sp140em1Vnce Ifnar1tm1Agt)
immune system phenotype J:313901
Ifnar1tm1Agt/Ifnar1tm1Agt
Tg(CD46)373Zbz/Tg(CD46)373Zbz

(involves: 129S2/SvPas * C3H/He * C57BL/6)
brain inflammation J:160878
increased susceptibility to Paramyxoviridae infection J:160878
increased susceptibility to Paramyxoviridae infection induced morbidity/mortality J:160878
lung inflammation J:160878
meningitis J:160878
Ifnar1tm1Agt/Ifnar1tm1Agt
Tg(Hmgcr-MX1)LStae/Tg(Hmgcr-MX1)LStae

(involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL)
decreased susceptibility to Orthomyxoviridae infection J:119783
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:119783
Ifnar1tm1Agt/Ifnar1tm1Agt
Ythdf3em1Caox/Ythdf3em1Caox

(involves: C57BL/6J)
abnormal macrophage physiology J:276397
Ifnar1tm1Pjh/Ifnar1tm1Pjh
(involves: 129S2/SvPas * BALB/c)
abnormal macrophage physiology J:36004
increased leukocyte cell number J:36004
increased susceptibility to Picornaviridae infection J:36004
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:36004
increased susceptibility to Togaviridae infection J:36004
increased susceptibility to Togaviridae infection induced morbidity/mortality J:36004
Ifnar1tm1Pjh/Ifnar1tm1Pjh
(B6.129S2-Ifnar1tm1Pjh)
decreased NK cell number J:125812
impaired natural killer cell mediated cytotoxicity J:125812
Ifnar2m1Btlr/Ifnar2m1Btlr
(C57BL/6J-Ifnar2m1Btlr)
abnormal macrophage physiology J:147329
decreased interferon-alpha secretion J:147329
decreased interferon-beta secretion J:147329
increased susceptibility to Adenoviridae infection J:147329
increased susceptibility to Herpesvirales infection J:147329
increased susceptibility to Orthomyxoviridae infection J:147329
increased susceptibility to Riboviria infection J:147329
Ifnar2tm1Pjh/Ifnar2tm1Pjh
(B6.Cg-Ifnar2tm1Pjh)
decreased NK cell number J:125812
impaired natural killer cell mediated cytotoxicity J:125812
Ifnar2tm1Pjh/Ifnar2tm1Pjh
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:132662
abnormal cytotoxic T cell physiology J:132662
decreased IgG1 level J:132662
decreased IgG2a level J:132662
decreased IgG level J:132662
decreased interferon-gamma secretion J:132662
Ifnar2tm1Pjh/Ifnar2tm1Pjh
Il6sttm1Ern/Il6sttm1Ern

(involves: 129S1/Sv)
increased circulating interleukin-6 level J:168781
increased susceptibility to endotoxin shock J:168781
Ifnb1tm1Acgp/Ifnb1tm1Acgp
(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating interferon-beta level J:61048
increased susceptibility to Poxviridae infection J:61048
Ifnb1tm1Acgp/Ifnb1tm1Acgp
(involves: 129P2/OlaHsd)
abnormal spleen primary B follicle morphology J:86527
decreased macrophage cell number J:86527
decreased mature B cell number J:86527
decreased monocyte cell number J:86527
decreased neutrophil cell number J:86527
decreased pro-B cell number J:86527
decreased tumor necrosis factor secretion J:86527
increased T cell proliferation J:86527
Ifnb1tm1Acgp/Ifnb1tm1Acgp
(B6.129P2-Ifnb1tm1Acgp)
abnormal macrophage physiology J:136368
decreased interleukin-1 beta secretion J:136368
Ifnb1tm1Tl/Ifnb1tm1Tl
(B10.129P2-Ifnb1tm1Tl)
abnormal macrophage physiology J:83021
abnormal microglial cell physiology J:83021
CNS inflammation J:83021
increased interferon-gamma secretion J:83021
increased interleukin-4 secretion J:83021
increased susceptibility to experimental autoimmune encephalomyelitis J:83021
increased tumor necrosis factor secretion J:83021
Ifnb1tm1Tl/Ifnb1tm1Tl
(B6.129P2-Ifnb1tm1Tl)
decreased circulating interferon-alpha level J:172226
decreased circulating interferon-beta level J:172226
decreased susceptibility to bacterial infection J:172226
Ifnb1tm1Ttg/Ifnb1tm1Ttg
(B6.Cg-Ifnb1tm1Ttg)
abnormal osteoclast morphology J:76097
Ifnb1tm1Ttg/Ifnb1tm1Ttg
(involves: C57BL/6)
abnormal response to infection J:116703
Ifnb1tm2.1Lien/Ifnb1tm2.1Lien
Tg(Itgax-cre)1-1Reiz/0
Tyrc-2J/Tyrc-2J

(involves: C57BL/6 * CBA)
immune system phenotype J:172226
Ifnb1tm2.1Lien/Ifnb1tm2.1Lien
Tyrc-2J/Tyrc-2J

(involves: C57BL/6)
immune system phenotype J:172226
Ifnb1tm2.1Lien/Ifnb1tm2.1Lien
Tyrc-2J/Tyrc-2J
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating interferon-alpha level J:172226
decreased circulating interferon-beta level J:172226
decreased susceptibility to bacterial infection J:172226
Ifnetm1.2Pjh/Ifnetm1.2Pjh
(involves: C57BL/6)
decreased NK cell number J:197569
increased susceptibility to bacterial infection J:197569
increased susceptibility to Herpesvirales infection J:197569
Ifngtm1.1Hayg/Ifngtm1.1Hayg
(Not Specified)
abnormal B cell differentiation J:220784
abnormal circulating cytokine level J:220784
abnormal cytokine level J:220784
abnormal lymph node morphology J:220784
abnormal T cell activation J:220784
decreased leukocyte cell number J:220784
decreased mature B cell number J:220784
decreased pre-B cell number J:220784
increased T cell number J:220784
spleen atrophy J:220784
thymus atrophy J:220784
Ifngtm1Lky/Ifngtm1Lky
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:189794
Ifngtm1Ts/Ifngtm1Ts
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal macrophage physiology J:66802
abnormal MHC II cell surface expression on macrophages J:66802
abnormal NK cell physiology J:66802, J:115033
abnormal type IV hypersensitivity reaction J:55740
decreased length of allograft survival J:44346
decreased susceptibility to parasitic infection J:189794
decreased susceptibility to parasitic infection induced morbidity/mortality J:189794
immune system phenotype J:119206
increased splenocyte proliferation J:66802
increased susceptibility to bacterial infection J:66802
Ifngtm1Ts/Ifngtm1Ts
(NOD.129S7-Ifngtm1Ts)
abnormal susceptibility to autoimmune disorder J:33427
decreased susceptibility to autoimmune diabetes J:95105
Ifngtm1Ts/Ifngtm1Ts
(NOD.Cg-Ifngtm1Ts Prkdcscid)
decreased susceptibility to autoimmune diabetes J:72818
Ifngtm1Ts/Ifngtm1Ts
(NOD.129S7(B6)-Ifngtm1Ts/DvsJ)
abnormal cytotoxic T cell physiology J:72818
abnormal diapedesis J:72818
decreased susceptibility to autoimmune diabetes J:72818
Ifngtm1Ts/Ifngtm1Ts
(involves: 129S7/SvEvBrd)
abnormal cytokine level J:112600
abnormal immunoglobulin level J:29170
abnormal response to infection J:110721, J:29170
decreased susceptibility to type IV hypersensitivity reaction J:29170
impaired natural killer cell mediated cytotoxicity J:73948
increased IgG1 level J:110721
increased interleukin-17 secretion J:132905
increased susceptibility to bacterial infection J:110856
increased susceptibility to bacterial infection induced morbidity/mortality J:110856
increased susceptibility to Herpesvirales infection J:29170
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:29170
Ifngtm1Ts/Ifngtm1Ts
(B6.129S7-Ifngtm1Ts/J)
abnormal circulating cytokine level J:47459
abnormal cytokine secretion J:120556
abnormal dendritic cell antigen presentation J:134949
abnormal dendritic cell chemotaxis J:134949
abnormal dendritic cell physiology J:134949
abnormal humoral immune response J:45665
abnormal immune tolerance J:45665
abnormal immunoglobulin level J:45665
abnormal Langerhans cell physiology J:134949
abnormal macrophage chemotaxis J:136628
abnormal spleen morphology J:47459
abnormal spleen red pulp morphology J:47459
abnormal spleen white pulp morphology J:47459
abnormal type IV hypersensitivity reaction J:45665
decreased interferon-gamma secretion J:120556
decreased interleukin-10 secretion J:120556, J:134949
decreased length of allograft survival J:44346
enlarged mesenteric lymph nodes J:50832
enlarged spleen J:47459
glomerulonephritis J:118730
immune system phenotype J:114783
increased circulating interleukin-6 level J:47459
increased granulocyte number J:47459
increased interleukin-4 secretion J:120556
increased interleukin-12 secretion J:134949
increased leukocyte cell number J:47459
increased monocyte cell number J:47459
increased NK T cell number J:122801
increased susceptibility to bacterial infection J:47459
increased susceptibility to bacterial infection induced morbidity/mortality J:47459
increased susceptibility to parasitic infection J:50832
increased susceptibility to parasitic infection induced morbidity/mortality J:50832
increased susceptibility to type IV hypersensitivity reaction J:118730
pale spleen J:47459
stomach inflammation J:120556
Ifngtm1Ts/Ifngtm1Ts
(B6.129S7-Ifngtm1Ts)
abnormal B cell physiology J:112084
abnormal cytokine secretion J:18801, J:110826
abnormal immunoglobulin level J:18801
abnormal lymph node cell ratio J:112084
abnormal response to infection J:18801, J:110826
abnormal response to transplant J:42090
decreased IgG2a level J:18801
decreased IgG3 level J:18801
increased CD8-positive, alpha-beta T cell number J:112048
increased IgE level J:18801
increased IgG1 level J:18801, J:112048
increased interleukin-2 secretion J:112048
increased interleukin-5 secretion J:112048
increased interleukin-10 secretion J:112048
increased susceptibility to Coronaviridae infection J:112048
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:112048
increased susceptibility to parasitic infection J:18801
increased susceptibility to parasitic infection induced morbidity/mortality J:18801, J:110826
Ifngtm1Ts/Ifngtm1Ts
(involves: 129S7/SvEvBrd * C57BL/6J)
increased susceptibility to bacterial infection J:15723
increased susceptibility to bacterial infection induced morbidity/mortality J:15723
Ifngtm1Ts/Ifngtm1Ts
(C.129S7-Ifngtm1Ts)
abnormal cytokine secretion J:110826
abnormal humoral immune response J:45665
abnormal immune tolerance J:45665
abnormal immunoglobulin level J:45665
abnormal response to infection J:110826
increased interleukin-5 secretion J:110826
increased susceptibility to bacterial infection induced morbidity/mortality J:83180
increased susceptibility to experimental autoimmune encephalomyelitis J:34161
increased susceptibility to parasitic infection J:110826
increased susceptibility to parasitic infection induced morbidity/mortality J:110826
Ifngtm1Ts/Ifngtm1Ts
(involves: 129S7/SvEvBrd * NOD)
immune system phenotype J:33427
Ifngtm1Ts/Ifngtm1Ts
(involves: 129S7/SvEvBrd * BALB/c)
abnormal susceptibility to infection J:39478
decreased IgE level J:114213
decreased inflammatory response J:114213
immune system phenotype J:39881
Ifngtm1Ts/Ifngtm1Ts
(involves: 129S7/SvEvBrd * DBA/1 * MRL/Mp)
decreased anti-double stranded DNA antibody level J:39600
decreased anti-nuclear antigen antibody level J:39600
decreased autoantibody level J:39600
decreased IgA level J:39600
decreased IgG2a level J:39600
decreased IgG2b level J:39600
decreased IgG3 level J:39600
decreased IgM level J:39600
decreased immunoglobulin level J:39600
decreased susceptibility to autoimmune disorder J:39600
Ifngtm1Ts/Ifngtm1Ts
(C.129S7(B6)-Ifngtm1Ts/J)
abnormal adaptive immunity J:115144
abnormal circulating cytokine level J:47459
abnormal cytokine secretion J:115144
abnormal cytotoxic T cell physiology J:115144
abnormal inflammatory response J:115144
abnormal macrophage physiology J:115144
abnormal NK cell physiology J:115144
abnormal spleen morphology J:115144
abnormal spleen red pulp morphology J:47459
abnormal spleen white pulp morphology J:47459
abnormal uterine NK cell morphology J:56503
abnormal uterine NK cell physiology J:56503
decreased susceptibility to parasitic infection J:50832
enlarged spleen J:47459
increased circulating interleukin-6 level J:47459
increased granulocyte number J:47459
increased leukocyte cell number J:47459
increased monocyte cell number J:47459
increased susceptibility to bacterial infection J:47459
increased susceptibility to bacterial infection induced morbidity/mortality J:47459
increased uterine NK cell number J:56503
pale spleen J:47459
Ifngtm1Ts/Ifngtm1Ts
(involves: 129S7/SvEvBrd * A/WySn * C57BL/10SnSg * Swiss)
decreased IgG2a level J:119207
decreased IgG level J:119207
decreased susceptibility to autoimmune disorder J:119207
increased IgG1 level J:119207
Ifngtm1Ts/Ifngtm1Ts
Ldlrtm1Her/Ldlrtm1Her

(B6.129S7-Ldlrtm1Her Ifngtm1Ts)
increased T cell number J:103072
Ifngtm1Ts/Ifngtm1Ts
Nlrp1aNeut1/Nlrp1aNeut1

(involves: 129S7/SvEvBrd * C57BL/6)
brain inflammation J:191055
immune system phenotype J:191055
Ifngtm1Ts/Ifngtm1Ts
Pld4tm1.2Nemz/Pld4tm1.2Nemz

(involves: 129 * 129S7/SvEvBrd * C57BL/6J * FVB/N)
decreased NK T cell number J:281205
Ifngtm1Ts/Ifngtm1Ts
Socs1tm1Jni/Socs1tm1Jni

(involves: 129S7/SvEvBrd)
increased interleukin-17 secretion J:132905
Ifngtm1Ts/Ifngtm1Ts
Socs1tm1Wehi/Socs1tm1Wehi

(involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6)
enlarged thymus medulla J:57474
Ifngtm1Ts/Ifngtm1Ts
Tg(SFTPC-Il18)AThos/0

(involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6N * DBA/2)
lung inflammation J:147547
Ifngtm1Ts/Ifngtm1Ts
Tgfb1tm1Doe/Tgfb1tm1Doe

(C.129-Ifngtm1Ts Tgfb1tm1Doe)
liver inflammation J:69346
Ifngtm1Ts/Ifngtm1Ts
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2 * NOD * SJL)
immune system phenotype J:196160
Ifngtm1Ts/Ifngtm1Ts
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6J)
small intestinal inflammation J:108572
Ifngtm1Ts/Ifngtm1Ts
Tnfrsf1atm1Blt/Tnfrsf1atm1Blt
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm

(involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd * C57BL/6)
abnormal lymph node cortex morphology J:119206
abnormal lymph node primary follicle morphology J:119206
abnormal lymph node secondary follicle morphology J:119206
absent lymph node germinal center J:119206
absent spleen germinal center J:119206
increased eosinophil cell number J:119206
increased leukocyte cell number J:119206
increased lymphocyte cell number J:119206
increased susceptibility to fungal infection J:119206
lung inflammation J:119206
small Peyer's patches J:119206
Ifngtm1Yiw/Ifngtm1Yiw
(involves: 129X1/SvJ * C57BL/6)
decreased inflammatory response J:41632, J:88226
Ifngtm1Yiw/Ifngtm1Yiw
(B6.129X1-Ifngtm1Yiw)
abnormal circulating interferon level J:91691
increased susceptibility to Coronaviridae infection J:91691, J:50405
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:91691, J:50405
liver inflammation J:50405
peritoneal inflammation J:50405
Ifngtm1Yiw/Ifngtm1Yiw
(C.129X1-Ifngtm1Yiw)
abnormal circulating interferon level J:91691
increased susceptibility to Coronaviridae infection J:91691
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:91691
Ifngr1m1Btlr/Ifngr1m1Btlr
(C57BL/6J-Ifngr1m1Btlr)
decreased macrophage cell number J:236694
decreased tumor necrosis factor secretion J:236694
increased B cell number J:236694
Ifngr1tm1.1Rds/Ifngr1tm1.1Rds
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(B6NTac.Cg-Ifngr1tm1.1Rds Commd10Tg(Vav1-icre)A2Kio)
increased susceptibility to bacterial infection J:206257
increased susceptibility to bacterial infection induced morbidity/mortality J:206257
Ifngr1tm1.1Rds/Ifngr1tm1.1Rds
Tg(Itgax-cre,-EGFP)4097Ach/0

(B6NTac.Cg-Ifngr1tm1.1Rds Tg(Itgax-cre,-EGFP)4097Ach)
decreased interferon-gamma secretion J:206257
decreased interleukin-12b secretion J:206257
increased susceptibility to bacterial infection J:206257
increased susceptibility to bacterial infection induced morbidity/mortality J:206257
Ifngr1tm1.1Rost/Ifngr1tm1.1Rost
(involves: BALB/cJ * C57BL/6)
abnormal chemokine level J:152785
decreased circulating interferon-gamma level J:152785
decreased circulating interleukin-12 level J:152785
immune system phenotype J:152785
Ifngr1tm1.2Rds/Ifngr1tm1.2Rds
(C57BL/6NTac-Ifngr1tm1.2Rds)
decreased interleukin-12b secretion J:206257
increased susceptibility to bacterial infection J:206257
increased susceptibility to bacterial infection induced morbidity/mortality J:206257
Ifngr1tm1Agt/Ifngr1tm1Agt
(involves: 129S7/SvEvBrd)
abnormal immunoglobulin level J:38363, J:101427
abnormal response to infection J:115139
abnormal uterine NK cell morphology J:56503
abnormal uterine NK cell physiology J:56503
aortitis J:115139
arteritis J:115139
decreased circulating tumor necrosis factor level J:17878
decreased IgG2a level J:38363
decreased susceptibility to endotoxin shock J:17878
increased circulating interferon-gamma level J:314959
increased circulating interleukin-1 beta level J:314959
increased circulating interleukin-6 level J:174397
increased interferon-gamma secretion J:38363
increased susceptibility to bacterial infection J:314959, J:174397
increased susceptibility to bacterial infection induced morbidity/mortality J:314959, J:174397
increased susceptibility to experimental autoimmune encephalomyelitis J:38363
increased susceptibility to Herpesvirales infection J:81243
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:115139
increased susceptibility to parasitic infection J:114203
increased susceptibility to Poxviridae infection J:101427
increased tumor necrosis factor secretion J:38363
increased uterine NK cell number J:56503
Ifngr1tm1Agt/Ifngr1tm1Agt
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal cytotoxic T cell physiology J:63815
decreased IgG2a level J:63815
decreased IgG3 level J:63815
decreased susceptibility to experimental autoimmune myasthenia gravis J:53577
increased interferon-gamma secretion J:99347
increased interleukin-6 secretion J:99347
increased splenocyte proliferation J:99347
increased susceptibility to bacterial infection J:63815
increased susceptibility to experimental autoimmune uveoretinitis J:99347
increased susceptibility to Riboviria infection J:63815
increased susceptibility to Riboviria infection induced morbidity/mortality J:63815
Ifngr1tm1Agt/Ifngr1tm1Agt
(B6.129S7-Ifngr1tm1Agt/J)
abnormal circulating chemokine level J:152785
abnormal lymphopoiesis J:138728
abnormal osteoclast differentiation J:233116
decreased CD4-positive, alpha-beta T cell number J:138728
decreased CD8-positive, alpha-beta T cell number J:138728
decreased circulating interleukin-12 level J:152785
decreased lymphocyte cell number J:138728
decreased susceptibility to bacterial infection J:147443
increased interferon-gamma secretion J:138728
increased susceptibility to graft versus host disease J:138728
spleen hypoplasia J:138728
Ifngr1tm1Agt/Ifngr1tm1Agt
(involves: 129S7/SvEvBrd * DBA/1OlaHsd)
decreased IgG2a level J:40634
increased susceptibility to induced arthritis J:40634
Ifngr1tm1Agt/Ifngr1tm1Agt
(129-Ifngr1tm1Agt/J)
immune system phenotype J:286237
Ifngr1tm1Agt/Ifngr1tm1Agt
Tg(GZMB-Tax)#Lera/0

(involves: 129S7/SvEvBrd * C57BL/6)
abnormal osteoclast differentiation J:147601
abnormal osteoclast physiology J:147601
increased osteoclast cell number J:147601
Ifngr1tm1Dmer/Ifngr1tm1Dmer
(B6.Cg-Ifngr1tm1Dmer)
abnormal response to infection J:202844
Ifngr1tm1Dmer/Ifngr1tm1Dmer
Tg(Thy1-cre)1Vln/0

(B6.Cg-Ifngr1tm1Dmer Tg(Thy1-cre)1Vln)
abnormal response to infection J:202844
Ifngr2tm1Pbro/Ifngr2tm1Pbro
(involves: 129S1/Sv)
abnormal class switch recombination J:48016
abnormal T-helper 1 cell differentiation J:48016
decreased susceptibility to type IV hypersensitivity reaction J:48016
increased susceptibility to bacterial infection J:48016
Ifngr2tm1Pbro/Ifngr2tm1Pbro
(NOD.129S1-Ifngr2tm1Pbro)
abnormal cytotoxic T cell physiology J:72818
abnormal diapedesis J:72818
abnormal T-helper 2 physiology J:65986
decreased susceptibility to autoimmune diabetes J:72818
Ifnktm1.1(KOMP)Vlcg/Ifnktm1.1(KOMP)Vlcg
(C57BL/6NTac-Ifnktm1.1(KOMP)Vlcg)
decreased susceptibility to chemically induced skin inflammation J:322130
enlarged spleen J:322130
Ifnl3em1Mtba/Ifnl3em1Mtba
(involves: C57BL/6)
abnormal circulating interferon level J:287260
increased susceptibility to Orthomyxoviridae infection J:287260
increased susceptibility to Riboviria infection J:287260
increased susceptibility to viral infection J:287260
Ifnlr1tm1b(EUCOMM)Wtsi/Ifnlr1tm1b(EUCOMM)Wtsi
(B6(Cg)-Ifnlr1tm1b(EUCOMM)Wtsi)
increased susceptibility to Orthomyxoviridae infection J:287260
increased susceptibility to Riboviria infection J:287260
increased susceptibility to viral infection J:287260
Ifnlr1tm1Palu/Ifnlr1tm1Palu
(B6.Cg-Ifnlr1tm1Palu)
abnormal susceptibility to infection J:131989
Ifnlr1tm1Palu/Ifnlr1tm1Palu
(involves: BALB/c * C57BL/6)
immune system phenotype J:286237
Ift70bem1(IMPC)Bay/Ift70bem1(IMPC)Bay
(C57BL/6N-Ift70bem1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Ift140b2b1283Clo/Ift140b2b1283Clo
(C57BL/6J-Ift140b2b1283Clo)
absent spleen J:175213
Iftaptm1Mnz/Iftaptm1Mnz
(Not Specified)
immune system phenotype J:254587
Igbp1tm1Cbt/Y
Tg(Lck-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
decreased thymocyte number J:93221
Igbp1tm1Cbt/Igbp1+
Tg(Lck-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
decreased thymocyte number J:93221
Igbp1tm1Imku/Y
Tg(Lck-cre)I57Jxm/?

(involves: 129P2/OlaHsd * ICR)
abnormal thymus cortex morphology J:84395
abnormal thymus corticomedullary boundary morphology J:84395
decreased double-negative T cell number J:84395
decreased T cell number J:84395
decreased thymocyte number J:84395
Igdcc4em1Bcgen/Igdcc4em1Bcgen
(involves: C57BL/6J)
decreased susceptibility to Orthomyxoviridae infection J:320015
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:320015
Igf1tm1.1Dlr/Igf1tm1.1Dlr
Tg(Ttr-IGF1)1Sykr/0

(FVB.Cg-Igf1tm1.1Dlr Tg(Ttr-IGF1)1Sykr)
increased spleen weight J:157350
Igf1rtm1Jcbr/Igf1rtm1Jcbr
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(B6.Cg-Ndor1Tg(UBC-cre/ERT2)1Ejb Igf1rtm1Jcbr)
decreased susceptibility to type I hypersensitivity reaction J:241924
Igf1rtm2Arge/Igf1rtm2Arge
Tg(BGLAP-cre)1Clem/0

(involves: 129 * FVB/N)
abnormal osteoclast physiology J:80190
decreased osteoclast cell number J:80190
Igf1sl2C3H/HeJ/Igf1sl2C3H/HeJ
(B6.C3H-Igf1sl2C3H/HeJ)
increased osteoclast cell number J:111677
Igf2tm1Snha/Igf2+
(involves: 129S1/Sv * 129X1/SvJ * ICR)
abnormal osteoclast differentiation J:167738
Igf2bp1Gt(OST33739)Lex/Igf2bp1Gt(OST33739)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
spleen hypoplasia J:89882
Igfbp1tm1Taub/Igfbp1tm1Taub
(involves: 129X1/SvJ * C57BL/6)
liver inflammation J:81123
Igfbp2tm1Jep/Igfbp2tm1Jep
(either: (involves: 129P1/ReJ * 129S/SvEv) or (involves: 129S/SvEv * C57BL/6))
small spleen J:64338
Igh-7tm1.1Lam/Igh-7tm1.1Lam
(involves: BALB/c)
decreased IgE level J:146733
decreased mature B cell number J:146733
Igh-7tm1Gach/Igh-7tm1Gach
(BALB/c-Igh-7tm1Gach)
abnormal B cell number J:143266
abnormal B cell physiology J:143266
increased IgE level J:143266
increased memory B cell number J:143266
increased plasma cell number J:143266
Igh-7tm1Lam/Igh-7tm1Lam
(involves: BALB/c)
decreased IgE level J:146733
decreased mature B cell number J:146733
Igh-7tm1Lcwu/Igh-7tm1Lcwu
(involves: C57BL/6)
decreased IgE level J:161452
decreased mature B cell number J:161452
Igh-7tm1Led/Igh-7tm1Led
(involves: 129S4/SvJae * Black Swiss)
immune system phenotype J:19552
Igh-7tm1Led/Igh-7tm1Led
(C.129S4-Igh-7tm1Led)
impaired eosinophil recruitment J:133373
Igh-7tm1Led/Igh-7tm1Led
Lyntm1Ard/Lyntm1Ard

(involves: 129P2/OlaHsd * 129S4/SvJae)
abnormal circulating complement protein level J:161523
decreased B cell number J:161523
increased anti-double stranded DNA antibody level J:161523
increased anti-nuclear antigen antibody level J:161523
increased basophil cell number J:161523
increased IgA level J:161523
increased IgM level J:161523
Igh-8tm1.1Aak/Igh-8tm1.1Aak
(involves: 129S2/SvPas * C57BL/6)
abnormal class switch recombination J:171251
Igh-8tm1Aak/Igh-8tm1Aak
(involves: 129S2/SvPas * C57BL/6)
abnormal class switch recombination J:107063
Igh-8tm1Schr/Igh-8tm1Schr
(involves: 129P2/OlaHsd * Black Swiss)
increased IgM level J:49847
Igh-8tm1Schr/Igh-8tm1Schr
(C.129P2(BKSW)-Igh-8tm1Schr)
increased IgG level J:75577
increased IgM level J:75577
increased susceptibility to bacterial infection J:75577
Igh-8tm2(Ighg1)Aak/Igh-8tm2(Ighg1)Aak
(involves: 129S2/SvPas)
abnormal class switch recombination J:130574
decreased IgG3 level J:130574
Igh-8tm2.1Aak/Igh-8tm2.1Aak
(involves: 129S2/SvPas * C57BL/6)
immune system phenotype J:171251
Igh-Jtm1(3H9-VDJ)Mwg/Igh-Jtm1(3H9-VDJ)Mwg
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal B cell receptor editing J:126940
Igh-Jtm1(CB20)Riho/Igh-J+
(involves: C57BL/10 * DBA/1)
abnormal B cell differentiation J:179456
decreased pre-B cell number J:179456
increased immature B cell number J:179456
increased marginal zone B cell number J:179456
increased mature B cell number J:179456
increased susceptibility to induced arthritis J:179456
Igh-Jtm1(CB20)Riho/Igh-Jtm1(CB20)Riho
(involves: C57BL/10 * DBA/1)
abnormal B cell differentiation J:179456
decreased pre-B cell number J:179456
increased immature B cell number J:179456
increased marginal zone B cell number J:179456
increased mature B cell number J:179456
increased susceptibility to induced arthritis J:179456
Igh-Jtm1(Ighel)Cys/Igh-Jtm1(Ighel)Cys
Myd88tm1Aki/Myd88tm1Aki
Igkj1tm1(IgkHyHEL10)Mnz/0

(involves: 129P2/OlaHsd)
increased IgM level J:115059
Igh-Jtm1(VDJ-KL25)Zbz/Igh-J+
(involves: C57BL/6 * C57BL/6J * BALB/cJ)
increased IgG level J:86411
increased IgM level J:86411
Igh-Jtm1(VDJ-VI10)Zbz/Igh-J+
(involves: C57BL/6 * C57BL/6J * BALB/cJ)
abnormal immune serum protein physiology J:86411
Igh-Jtm1.1Lave/Igh-J+
(Not Specified)
abnormal B cell differentiation J:155798
decreased B cell number J:155798
decreased immature B cell number J:155798
decreased mature B cell number J:155798
decreased spleen weight J:155798
decreased T cell number J:155798
decreased transitional stage B cell number J:155798
decreased transitional stage T1 B cell number J:155798
decreased transitional stage T2 B cell number J:155798
increased pre-B cell number J:155798
increased pro-B cell number J:155798
Igh-Jtm1.1Lave/Igh-Jtm1.1Lave
(Not Specified)
abnormal B cell differentiation J:155798
abnormal immunoglobulin level J:179317
arrested B cell differentiation J:179317
decreased B cell number J:155798, J:179317
decreased IgM level J:155798
decreased immature B cell number J:155798
decreased mature B cell number J:155798
decreased spleen weight J:155798
decreased T cell number J:155798
decreased transitional stage B cell number J:155798
decreased transitional stage T1 B cell number J:155798
decreased transitional stage T2 B cell number J:155798
increased IgG level J:155798
increased pre-B cell number J:155798
increased pro-B cell number J:155798
Igh-Jtm1.1Lave/Igh-Jtm1.1Lave
Igk-Jtm1.1Lave/Igk-Jtm1.1Lave

(Not Specified)
abnormal B cell clonal deletion J:179317
abnormal B cell differentiation J:205708
abnormal B cell physiology J:205708
abnormal immunoglobulin level J:179317
arrested B cell differentiation J:205708, J:179317
decreased B cell number J:205708, J:179317
decreased immature B cell number J:205708
decreased mature B cell number J:205708
Igh-Jtm1.1Lave/Igh-Jtm1.1Lave
Igk-Jtm1.1Lave/Igk-Jtm1.1Lave
Tg(BCL2)22Wehi/0

(involves: C57BL/6JWehi * SJL/JWehi)
abnormal B cell differentiation J:179317
Igh-Jtm1Aigl/Igh-J+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal B cell morphology J:111543
decreased B cell number J:111543
decreased B-1 B cell number J:111543
increased susceptibility to experimental autoimmune encephalomyelitis J:111543
Igh-Jtm1Aigl/Igh-J+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
increased susceptibility to experimental autoimmune encephalomyelitis J:111543
Igh-Jtm1Aigl/Igh-J+
Mogtm1Dpd/Mogtm1Dpd
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6)
CNS inflammation J:151335
increased susceptibility to experimental autoimmune encephalomyelitis J:151335
Igh-Jtm1Aigl/Igh-J+
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
CNS inflammation J:151335
increased susceptibility to experimental autoimmune encephalomyelitis J:151335
Igh-Jtm1Aigl/Igh-Jtm1Aigl
Tg(H2-Kb-Tcra,-Tcrb)1640Kurs/0

(involves: 129S1/Sv * 129X1/SvJ * FVB/N * SJL/J)
increased autoantibody level J:149511
increased susceptibility to experimental autoimmune encephalomyelitis J:149511
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0

(Not Specified)
decreased B cell number J:79299
decreased follicular B cell number J:79299
decreased marginal zone B cell number J:79299
Igh-Jtm1Cgn/Ightm4Cgn
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd)
decreased mature B cell number J:157297
Igh-Jtm1Cgn/Ightm11.1Cgn
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:113434
Igh-Jtm1Cgn/Igh-J+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:64285
Igh-Jtm1Cgn/Ightm1Leck
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immunoglobulin light chain V-J recombination J:144033
Igh-Jtm1Cgn/Igh-Jtm1Cgn
(involves: 129P2/OlaHsd * C57BL/6)
absent mature B cells J:64285
arrested B cell differentiation J:64285
Igh-Jtm1Dhu/Ightm3Tim
(involves: 129 * C57BL/6)
abnormal B cell differentiation J:102308
decreased B cell number J:102308
Igh-Jtm1Dhu/Ightm1Tim
(involves: 129X1/SvJ * C57BL/6)
abnormal B cell differentiation J:88410
abnormal B cell morphology J:87624
abnormal immune system organ morphology J:87624
abnormal spleen marginal zone morphology J:87624
abnormal spleen morphology J:87624
Igh-Jtm1Dhu/Ightm2Tim
(involves: 129X1/SvJ * C57BL/6)
abnormal lymph node morphology J:87624
abnormal spleen morphology J:87624
decreased marginal zone B cell number J:87624
Igh-Jtm1Dhu/Igh-J+
Il2tm1Hor/Il2tm1Hor

(involves: 129/Sv * C57BL/6)
colitis J:29999
enlarged mesenteric lymph nodes J:29999
Igh-Jtm1Dhu/Igh-Jtm1(VDJ-17.2.25)Wabl
Igktm1Dhu/Igktm1Dhu

(Not Specified)
abnormal B cell differentiation J:33628
abnormal immature B cell morphology J:89757
Igh-Jtm1Dhu/Igh-Jtm1Dhu
Il2tm1Hor/Il2tm1Hor

(involves: 129/Sv * C57BL/6)
colitis J:29999
enlarged mesenteric lymph nodes J:29999
Igh-Jtm1Dhu/Igh-Jtm1Dhu
Wdr1rede/Wdr1rede

(involves: 129S7/SvEvBrd * BALB/c * C57BL/6)
abnormal immune system physiology J:134092
Igh-Jtm1Dim/Igh-J+
Igk-Jtm1Dim/Igk-J+

(involves: 129S4/SvJae * C57BL/6)
abnormal B cell differentiation J:107241
increased IgG level J:107241
increased IgM level J:107241
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell number J:113083
absent B cells J:70038
decreased IgM level J:70038
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
(involves: 129P2/OlaHsd)
absent mature B cells J:137738
arrested B cell differentiation J:137738
increased late pro-B cell number J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv

(involves: 129P2/OlaHsd)
absent B cells J:23827
absent mature B cells J:137738, J:70620
arrested B cell differentiation J:137738, J:23827
increased late pro-B cell number J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yH1)2BJkbv/0
Tg(IGK@yK1)9.2CJkbv/0

(involves: 129P2/OlaHsd)
abnormal B cell morphology J:23827
abnormal immunoglobulin level J:23827
increased mature B cell number J:23827
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yH1)2BJkbv/0
Tg(IGK@yK1)9.2CJkbv/Tg(IGK@yK1)9.2CJkbv

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:137738
decreased immature B cell number J:137738
decreased mature B cell number J:137738
decreased pre-B cell number J:137738
increased late pro-B cell number J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yH1)2BJkbv/Tg(IGH@yH1)2BJkbv
Tg(IGK@yK1)9.2CJkbv/Tg(IGK@yK1)9.2CJkbv

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:137738
abnormal immunoglobulin level J:137738
decreased immature B cell number J:137738
decreased mature B cell number J:137738
decreased pre-B cell number J:137738
increased late pro-B cell number J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yH1)2BJkbv/Tg(IGH@yH1)2BJkbv
Tg(IGK@yK2)J23.1Jkbv/Tg(IGK@yK2)J23.1Jkbv

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:137738
decreased immature B cell number J:137738
decreased mature B cell number J:137738
decreased pre-B cell number J:137738
increased late pro-B cell number J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yH2)J9.2Jkbv/0
Tg(IGK@yK2)J23.1Jkbv/0

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell morphology J:70620
abnormal immunoglobulin heavy chain V(D)J recombination J:70620
abnormal immunoglobulin level J:70620
abnormal immunoglobulin light chain V-J recombination J:70620
increased mature B cell number J:70620
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yH2)J9.2Jkbv/0
Tg(IGK@yK2)J23.1Jkbv/Tg(IGK@yK2)J23.1Jkbv

(involves: 129P2/OlaHsd)
abnormal immunoglobulin level J:137738
decreased immature B cell number J:137738
decreased mature B cell number J:137738
immune system phenotype J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yH2BM)7Amgn/0
Tg(IGK@yK2)J23.1Jkbv/0

(involves: 129P2/OlaHsd)
abnormal immunoglobulin level J:139792
decreased B cell number J:139792
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yH2CM)2Amgn/0
Tg(IGK@yK2)J23.1Jkbv/0

(involves: 129P2/OlaHsd)
abnormal immunoglobulin level J:139792
decreased B cell number J:139792
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yHG1/2)1Amgn/0
Tg(IGK@yK2)J23.1Jkbv/0

(involves: 129P2/OlaHsd)
abnormal immunoglobulin level J:139792
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGH@yHG4)1Amgn/0
Tg(IGK@yK2)J23.1Jkbv/0

(involves: 129P2/OlaHsd)
abnormal immunoglobulin level J:139792
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Tg(IGH@*)SALed/0

(involves: 129P2/OlaHsd)
decreased mature B cell number J:137738
immune system phenotype J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Tg(IGH@yH1)2BJkbv/0

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:137738
decreased mature B cell number J:137738
decreased pre-B cell number J:137738
increased late pro-B cell number J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Tg(IGH@yH1)2BJkbv/0
Tg(IGK@yK1)9.2CJkbv/0

(involves: 129P2/OlaHsd)
abnormal B cell morphology J:23827
abnormal immunoglobulin level J:23827
increased late pro-B cell number J:23827
increased mature B cell number J:23827
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Tg(IGH@yH1)2BJkbv/Tg(IGH@yH1)2BJkbv

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:137738
abnormal immunoglobulin level J:137738
decreased immature B cell number J:137738
decreased mature B cell number J:137738
decreased pre-B cell number J:137738
increased late pro-B cell number J:137738
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Tg(IGH@yH2)J9.2Jkbv/0

(involves: 129P2/OlaHsd)
abnormal immunoglobulin level J:137738
decreased mature B cell number J:137738
immune system phenotype J:137738
Igh-Jtm1Khyk/Igh-J+
(CB17.129X1-Igh-Jtm1Khyk)
increased B-1 B cell number J:109979
Igh-Jtm1Mcdl/Igh-Jtm1Mcdl
Igk-Jtm1Mcdl/Igk-Jtm1Mcdl
Rag1tm1Mom/Rag1tm1Mom
Tg(DO11.10)10Dlo/?

(involves: 129S/Sv * BALB/c * C3H * C57BL/6)
abnormal spleen germinal center morphology J:100072
abnormal T cell differentiation J:100072
increased IgE level J:100072
increased IgG level J:100072
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal B cell receptor editing J:126940
increased anti-double stranded DNA antibody level J:126940
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
(involves: 129P2/OlaHsd * BALB/c)
abnormal B cell receptor editing J:131138
abnormal marginal zone B cell morphology J:131138
increased anti-double stranded DNA antibody level J:131138
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
(B6.129P2-Igh-Jtm2(3H9-VDJ*)Mwg)
decreased B cell number J:142389
increased anti-double stranded DNA antibody level J:142389
increased marginal zone B cell number J:142389
spleen hypoplasia J:142389
Igh-Jtm2.1(4E10)Lave/Igh-Jtm2.1(4E10)Lave
(involves: C57BL/6)
arrested B cell differentiation J:205708
decreased B-1a cell number J:205708
decreased IgG1 level J:205708
decreased IgG2b level J:205708
decreased IgG3 level J:205708
decreased IgG level J:205708
decreased IgM level J:205708
Igh-Jtm2.1(4E10)Lave/Igh-Jtm2.1(4E10)Lave
Igk-Jtm2.1(4E10)Lave/Igk-Jtm2.1(4E10)Lave

(involves: C57BL/6)
abnormal B cell differentiation J:205708
abnormal B cell physiology J:205708
arrested B cell differentiation J:205708
decreased immature B cell number J:205708
decreased mature B cell number J:205708
Igh-Jtm3(3H9-VDJ*)Mwg/Igh-Jtm3(3H9-VDJ*)Mwg
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal B cell receptor editing J:126940
increased anti-double stranded DNA antibody level J:126940
Igh-Jtm3.1(48d)Lave/Igh-Jtm3.1(48d)Lave
(involves: C57BL/6)
decreased B-1a cell number J:205708
decreased IgG1 level J:205708
decreased IgG2b level J:205708
decreased IgM level J:205708
immune system phenotype J:205708
Igh-V7183tm1Cgn/Igh-V7183tm1Cgn
(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6))
immune system phenotype J:112978
Igh-Vtm1Jjk/Igh-Vtm1Jjk
(involves: 129S4/SvJae * C57BL/6)
abnormal adaptive immunity J:62284
increased susceptibility to bacterial infection J:62284
IghdeltaD/Igh+
(involves: C57BL/6 * DBA/2)
abnormal B cell differentiation J:95981
decreased B cell number J:95981
decreased immunoglobulin level J:95981
IghdeltaD/IghdeltaD
(involves: C57BL/6 * DBA/2)
abnormal B cell differentiation J:95981
abnormal immunoglobulin level J:95981
abnormal spleen morphology J:95981
arrested B cell differentiation J:95981
decreased B cell number J:95981
decreased follicular B cell number J:95981
decreased IgG1 level J:95981
increased IgA level J:95981
increased marginal zone B cell number J:95981
IghdeltaD/Ightm11.1Cgn
(involves: C57BL/6 * DBA/2)
abnormal B cell differentiation J:113434
Ightm1(IGH)Vlcg/Ightm1(IGH)Vlcg
Igktm1(IGK)Vlcg/Igktm1(IGK)Vlcg

(involves: 129S6/SvEvTac * C57BL/6N)
immune system phenotype J:208620
Ightm1(Ighppc1-5)Cche/Igh+
(B6.Cg-Ightm1(Ighppc1-5)Cche)
immune system phenotype J:138356
increased autoantibody level J:138356
Ightm1(Myc)Janz/Igh+
(involves: 129X1/SvJ * C57BL/6)
enlarged lymph nodes J:96785
enlarged spleen J:96785
increased B cell apoptosis J:96785
increased B cell proliferation J:96785
lymphoid hyperplasia J:96785
Ightm1(Myc)Janz/Igh+
Mdm4tm1.1Wahl/Mdm4tm1.1Wahl

(involves: 129S/Sv * C57BL/6)
enlarged lymph nodes J:150341
enlarged spleen J:150341
increased splenocyte proliferation J:150341
Ightm1(PAX5)Mbu/Igh+
(B6.Cg-Ightm1(PAX5)Mbu)
abnormal lymph node morphology J:118111
abnormal spleen morphology J:118111
abnormal T cell differentiation J:118111
abnormal thymus morphology J:118111
decreased double-negative T cell number J:118111
decreased double-positive T cell number J:118111
enlarged lymph nodes J:118111
enlarged spleen J:118111
enlarged thymus J:118111
increased pro-B cell number J:118111
thymus hypoplasia J:118111
Ightm1(PAX5)Mbu/Igh+
Pax5tm1Mbu/Pax5tm1Mbu

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * CBA)
abnormal B cell differentiation J:118111
decreased B cell number J:118111
immune system phenotype J:118111
Ightm1(PAX5)Mbu/Ightm1(PAX5)Mbu
(B6.Cg-Ightm1(PAX5)Mbu)
abnormal lymph node morphology J:118111
abnormal spleen morphology J:118111
abnormal T cell differentiation J:118111
abnormal thymus morphology J:118111
decreased double-negative T cell number J:118111
decreased double-positive T cell number J:118111
enlarged lymph nodes J:118111
enlarged spleen J:118111
enlarged thymus J:118111
increased pro-B cell number J:118111
thymus hypoplasia J:118111
Ightm1(VH558)Mss/Igh+
(involves: FVB/N)
abnormal B cell differentiation J:130421
Ightm1(VH558)Mss/Ightm1(VH558)Mss
(involves: FVB/N)
abnormal B cell differentiation J:130421
Ightm1.1(b12)Nemz/Ightm1.1(b12)Nemz
(involves: C57BL/6N * FVB/N)
decreased IgM level J:205766
decreased immature B cell number J:205766
increased B cell number J:205766
Ightm1.1(b12)Nemz/Ightm1.1(b12)Nemz
Igktm1.1(b12)Nemz/Igktm1.1(b12)Nemz

(involves: C57BL/6N * C57BL/6NTac * FVB/N)
decreased IgM level J:205766
decreased immature B cell number J:205766
immune system phenotype J:205766
increased B cell number J:205766
Ightm1.1(Igh564)Tik/Ightm1.1(Igh564)Tik
Igktm1(Igk564)Tik/Igktm1(Igk564)Tik

(B6.129S4-Igktm1(Igk564)Tik Ightm1(Igh564)Tik)
glomerulonephritis J:113555
Ightm1.1(Rr361-HBB)Aak/Ightm1.1(Rr361-HBB)Aak
(129.129S2(Cg)-Ightm1.1(Rr361-HBB)Aak)
abnormal class switch recombination J:333279
decreased IgA level J:333279
decreased IgE level J:333279
decreased IgG1 level J:333279
decreased IgG2a level J:333279
decreased IgG2b level J:333279
Ightm1.1(Tag)Rwhe/Igh+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell morphology J:150315
enlarged spleen J:150315
increased B cell number J:150315
lymph node hyperplasia J:150315
Ightm1.1Hmj/Ightm1.1Hmj
(involves: 129S6/SvEvTac * C57BL/6J * FVB/N)
abnormal B cell differentiation J:140486
abnormal immunoglobulin heavy chain V(D)J recombination J:140486
decreased mature B cell number J:140486
immune system phenotype J:140486
spleen hypoplasia J:140486
Ightm1.1Hws/Ightm1.1Hws
(BALB/cJ-Ightm1.1Hws)
decreased IgM level J:119391
decreased immature B cell number J:119391
decreased immunoglobulin level J:119391
decreased pre-B cell number J:119391
increased late pro-B cell number J:119391
Ightm1.1Hws/Ightm1.1Hws
(involves: BALB/c)
decreased immature B cell number J:142069
decreased late pro-B cell number J:142069
increased early pro-B cell number J:142069
increased IgG3 level J:142069
increased IgM level J:142069
Ightm1.1Lnit/Igh+
(involves: BALB/c * C57BL/6)
abnormal B cell differentiation J:119484
Ightm1.1Rsky/Ightm1.1Rsky
(BALB/c-Ightm1.1Rsky)
abnormal class switch recombination J:125719
decreased IgM level J:125719
Ightm1.1Twin/Igh+
(involves: 129 * 129S4/SvJae * C57BL/6)
decreased pre-B cell number J:174233
increased pro-B cell number J:174233
Ightm1.1Twin/Ightm1.1Twin
(involves: 129 * 129S4/SvJae * C57BL/6)
abnormal B cell differentiation J:174233
abnormal B cell morphology J:174233
abnormal B cell number J:174233
abnormal marginal zone B cell morphology J:174233
abnormal marginal zone B cell physiology J:174233
absent plasma cells J:174233
decreased B cell number J:174233
decreased B-1a cell number J:174233
decreased follicular B cell number J:174233
decreased IgG3 level J:174233
decreased IgG level J:174233
decreased IgM level J:174233
decreased immature B cell number J:174233
decreased mature B cell number J:174233
decreased transitional stage T2 B cell number J:174233
immune system phenotype J:174233
Ightm1.1Twin/Ightm1.1Twin
Plcg2Ali5/Plcg2+

(involves: 129 * 129S4/SvJae * C3HeB/FeJ * C57BL/6)
immune system phenotype J:174233
increased B-1a cell number J:174233
Ightm1.1Twin/Ightm1.1Twin
Siglecgtm1Lnit/Siglecgtm1Lnit

(involves: 129 * 129S4/SvJae * BALB/c * C57BL/6)
immune system phenotype J:174233
Ightm1.1Vmd/Igh+
(involves: C57BL/6)
abnormal class switch recombination J:201147
Ightm1.1Vmd/Ightm1.1Vmd
(involves: C57BL/6)
abnormal class switch recombination J:201147
decreased IgG1 level J:201147
decreased IgG3 level J:201147
immune system phenotype J:201147
increased IgE level J:201147
Ightm1.2Rsky/Igh+
(BALB/c-Ightm1.2Rsky)
increased IgG1 level J:125719
Ightm1.2Rsky/Igh+
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass

(involves: BALB/c * C57BL/6)
decreased mature B cell number J:125719
Ightm1.2Rsky/Ightm1.2Rsky
(BALB/c-Ightm1.2Rsky)
abnormal B cell activation J:125719
abnormal B cell morphology J:125719
abnormal B cell proliferation J:125719
abnormal mature B cell morphology J:125719
decreased B-1a cell number J:125719
decreased IgA level J:125719
decreased IgD level J:125719
decreased IgE level J:125719
decreased IgM level J:125719
decreased immunoglobulin level J:125719
decreased pre-B cell number J:125719
decreased transitional stage B cell number J:125719
increased marginal zone B cell number J:125719
increased pro-B cell number J:125719
Ightm1.2Rsky/Ightm1.2Rsky
Tg(CD19-cre/ERT2)1Cgn/?

(involves: BALB/c)
abnormal B cell activation J:125719
abnormal class switch recombination J:125719
Ightm1Aak/Ightm1Aak
(Not Specified)
abnormal B cell differentiation J:158402
decreased B cell number J:158402
decreased pre-B cell number J:158402
increased pro-B cell number J:158402
Ightm1Cgn/Igh+
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:79556
Ightm1Cgn/Ightm2Cgn
(involves: 129P2/OlaHsd * BALB/c * C57BL/Ka)
abnormal B cell differentiation J:79556
Ightm1Cog/Ightm1Cog
(involves: 129S2/SvPas * C57BL/6)
abnormal immunoglobulin heavy chain V(D)J recombination J:80654
absent B cells J:80654
arrested B cell differentiation J:80654
decreased IgA level J:80654
decreased IgE level J:80654
decreased IgG1 level J:80654
decreased IgG2a level J:80654
decreased IgG2b level J:80654
decreased IgG3 level J:80654
decreased IgM level J:80654
decreased immunoglobulin level J:80654
Ightm1Cys/Igh+
Tg(Igk)5Cys/0

(B6.Cg-Ightm1Cys Tg(Igk)5Cys)
abnormal B cell physiology J:118931
immune system phenotype J:118931
Ightm1Cys/Igh+
Tg(Igk)5Cys/0
Tg(UBC-GFP)30Scha/Tg(UBC-GFP)30Scha

(involves: 129X1/SvJ * C57BL/6 * CBA)
immune system phenotype J:118931
Ightm1Emo/Ightm1Emo
(involves: 129S1/Sv * C57BL/6 * FVB/N)
immune system phenotype J:108098
Ightm1Kplm/Igh+
(involves: A/WySnJ * BALB/c)
abnormal B-1 B cell morphology J:115788
Ightm1Kplm/Igh+
(Not Specified)
abnormal B cell differentiation J:115292
increased B cell number J:115292
Ightm1Kplm/Igh+
Tg(Igk-V4CH27)1-2Shc/0

(involves: C57BL/6 * SJL)
increased B cell number J:115292
Ightm1Kplm/Ightm3Cgn
(involves: C57BL/6)
abnormal B cell differentiation J:115292
abnormal B cell number J:115292
Ightm1Kplm/Ightm4Cgn
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:115292
abnormal B cell number J:115292
abnormal B-1 B cell morphology J:115292
Ightm1Kplm/Ightm4Cgn
Tg(Igk-V4CH27)1-2Shc/0

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
increased B cell number J:115292
Ightm1Ktom/Ightm1Ktom
(involves: ICR)
abnormal B cell physiology J:59894
abnormal immunoglobulin level J:178635
absent mature B cells J:178635
Ightm1Ktom/Ightm1Ktom
Igktm1Ktom/Igktm1Ktom
Tc(HSA14)SC20Ktom/0
Tc(HSA2)W23Ktom/0

(involves: C57BL/6NCrlj * CBA/JNCrlj * ICR)
abnormal B cell physiology J:59894
Ightm1Ktom/Ightm1Ktom
Tc(HSA2)W23Ktom/0

(involves: C57BL/6NCrlj * CBA/JNCrlj * ICR)
abnormal B cell physiology J:59894
Ightm1Leck/Igh+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell morphology J:144033
abnormal B-1a B cell morphology J:144033
abnormal immature B cell morphology J:144033
abnormal immunoglobulin light chain V-J recombination J:144033
abnormal mature B cell morphology J:144033
Ightm1Leck/Ightm1Leck
(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:144033
Ightm1Mnz/Ightm1Mnz
(B6.129P2-Ightm1Mnz)
abnormal B cell physiology J:75653
increased B cell apoptosis J:75653
increased B cell proliferation J:75653
increased IgG level J:75653
increased IgM level J:75653
Ightm1Mnz/Ightm1Mnz
Dis3tm1.1Uba/Dis3tm1.1Uba
Aicdatm1(cre)Uba/Aicda+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6)
abnormal somatic hypermutation frequency J:302856
Ightm1Mnz/Ightm1Mnz
Lyntm1Sor/Lyntm1Sor

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6)
abnormal B cell physiology J:75653
increased B cell proliferation J:75653
Ightm1Rbr/Igh+
(C57BL/6-Ightm1Rbr)
abnormal B cell morphology J:132538
Ightm1Rbr/Igh+
Tg(IgkHyHEL10)1Rbr/0

(involves: C57BL/6)
abnormal B cell morphology J:132538
abnormal B-2 B cell morphology J:132538
increased IgA level J:132538
increased IgG1 level J:132538
increased IgG2a level J:132538
increased IgG2b level J:132538
increased IgG3 level J:132538
increased IgM level J:132538
increased immature B cell number J:132538
increased immunoglobulin level J:132538
Ightm1Rbr/Igh+
Tg(IgkHyHEL10)1Rbr/0
Tg(ML5sHEL)5Ccg/0

(involves: C57BL/6 * C57BL/6JSfd)
abnormal B cell anergy J:132538
abnormal B cell morphology J:132538
decreased follicular B cell number J:132538
decreased marginal zone B cell number J:132538
increased immature B cell number J:132538
Ightm2(IGH)Vlcg/Ightm2(IGH)Vlcg
Igktm2(IGK)Vlcg/Igktm2(IGK)Vlcg

(involves: 129S6/SvEvTac * C57BL/6N)
immune system phenotype J:208620
Ightm2.1(4E10)Nemz/Ightm2.1(4E10)Nemz
Igktm2.1(4E10)Nemz/Igktm2.1(4E10)Nemz

(involves: C57BL/6 * C57BL/6N * C57BL/6NTac * FVB/N)
decreased B cell number J:101977
decreased IgG level J:101977
decreased IgM level J:101977
Ightm2.1(Tag)Rwhe/Igh+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell morphology J:150315
enlarged spleen J:150315
increased B cell number J:150315
lymph node hyperplasia J:150315
Ightm2.1Fwa/Ightm2.1Fwa
(involves: 129S/SvEv * C57BL/6)
abnormal class switch recombination J:161437
abnormal somatic hypermutation frequency J:161437
decreased IgG1 level J:161437
decreased mature B cell number J:161437
immune system phenotype J:161437
increased IgE level J:161437
Ightm2.1Hws/Ightm2.1Hws
(involves: BALB/c * C57BL/6NCrl * DBA/2NCrl)
abnormal humoral immune response J:124421
decreased B cell number J:124421
decreased B-1a cell number J:124421
decreased B-1b cell number J:124421
decreased follicular B cell number J:124421
decreased IgG level J:124421
decreased IgM level J:124421
decreased pre-B cell number J:124421
decreased transitional stage B cell number J:124421
increased early pro-B cell number J:124421
increased marginal zone B cell number J:124421
Ightm2.1Hws/Ightm2.1Hws
(involves: BALB/c)
abnormal B cell differentiation J:142069
decreased B-1a cell number J:142069
decreased follicular B cell number J:142069
decreased IgM level J:142069
decreased immature B cell number J:142069
decreased late pro-B cell number J:142069
decreased mature B cell number J:142069
decreased transitional stage B cell number J:142069
increased anti-nuclear antigen antibody level J:142069
increased early pro-B cell number J:142069
increased marginal zone B cell number J:142069
Ightm2Cgn/Igh+
(involves: 129P2/OlaHsd * BALB/c * C57BL/Ka)
abnormal B cell differentiation J:79556
Ightm2Cgn/Igh+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immunoglobulin light chain V-J recombination J:144033
Ightm2Cgn/Igh+
Igktm1Rsky/Igk+

(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * BALB/c))
abnormal B cell differentiation J:111431
absent pre-B cells J:111431
Ightm2Cgn/Igh+
Igktm2Rsky/Igk+

(involves: 129P2/OlaHsd)
abnormal class switch recombination J:150435
Ightm2Cgn/Igh+
Igktm2Rsky/Igk+
Prkdcscid/Prkdcscid

(involves: 129P2/OlaHsd * BALB/c * C57BL/Ka)
abnormal class switch recombination J:150435
Ightm2Cgn/Igh+
Rr158tm1Cgn/Rr158tm1Cgn
Arhgef1tm1.1Rmt/Arhgef1tm1.1Rmt

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:113295
Ightm2Cgn/Igh+
Xrcc6tm1Fwa/Xrcc6tm1Fwa

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6)
abnormal B cell differentiation J:44361
Ightm2Cgn/Ightm2Cgn
Igktm1Rsky/Igktm1Rsky
Lig4tm1Fwa/Lig4tm1Fwa
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac)
abnormal class switch recombination J:126758
Ightm2Cgn/Ightm2Cgn
Igktm1Rsky/Igktm1Rsky
Trp53tm1Tyj/Trp53tm1Tyj
Xrcc4tm1Fwa/Xrcc4tm1Fwa

(involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac)
abnormal class switch recombination J:126758
Ightm2Cgn/Ightm3Cgn
(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * C57BL/Ka)
abnormal B cell differentiation J:79556
Ightm2Cgn/Ightm4.1Fwa
(involves: 129P2/OlaHsd * 129S6/SvEvTac)
abnormal immunoglobulin V(D)J recombination J:176649
Ightm2Cog/Igh+
(involves: 129S2/SvPas * C57BL/6)
decreased IgG1 level J:90548
decreased IgG2b level J:90548
decreased IgG3 level J:90548
decreased IgG level J:90548
Ightm2Cog/Ightm2Cog
(involves: 129S2/SvPas * C57BL/6)
decreased IgG1 level J:90548
decreased IgG2a level J:90548
decreased IgG2b level J:90548
decreased IgG3 level J:90548
decreased IgG level J:90548
increased pre-B cell number J:90548
Ightm2Emo/Ightm2Emo
(involves: 129S1/Sv * C57BL/6 * FVB/N)
abnormal B cell differentiation J:108098
absent pre-B cells J:108098
Ightm2Mnz/Ightm2Mnz
(B6.129P2-Ightm2Mnz)
increased B cell proliferation J:75653
increased IgG level J:75653
increased IgM level J:75653
Ightm2Mnz/Ightm2Mnz
Lyntm1Sor/Lyntm1Sor

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6)
abnormal B cell physiology J:75653
increased B cell proliferation J:75653
Ightm2Rsky/Igh+
Igktm1Rsky/Igk+

(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * BALB/c))
abnormal B cell differentiation J:111431
Ightm2Rsky/Igh+
Igktm2Rsky/Igk+

(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * BALB/c))
abnormal B cell differentiation J:111431
Ightm3.1(IGH)Vlcg/Ightm3.1(IGH)Vlcg
Igktm3.1(IGK)Vlcg/Igktm3.1(IGK)Vlcg

(involves: 129S6/SvEvTac * C57BL/6N)
immune system phenotype J:208620
Ightm3.1Cog/Ightm3.1Cog
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal class switch recombination J:71300
decreased IgA level J:71300
decreased IgE level J:71300
decreased IgG2a level J:71300
decreased IgG2b level J:71300
decreased IgG3 level J:71300
decreased IgG level J:71300
decreased immunoglobulin level J:71300
immune system phenotype J:71300
Ightm3.1Tim/Igh+
(involves: 129 * C57BL/6)
abnormal B cell differentiation J:102308
abnormal spleen B cell follicle morphology J:102308
Ightm3Cgn/Igh+
(involves: C57BL/6)
abnormal B cell differentiation J:79556, J:115292
Ightm3Cgn/Ightm3Cgn
(involves: C57BL/6)
abnormal immune system physiology J:76117
decreased immature B cell number J:76117
Ightm3Hws/Ightm3Hws
(BALB/c-Ightm3Hws)
abnormal immunoglobulin heavy chain V(D)J recombination J:142068
Ightm3Hws/Ightm3Hws
(involves: BALB/c)
abnormal immunoglobulin level J:142069
decreased B cell number J:142069
decreased follicular B cell number J:142069
decreased IgG1 level J:142069
decreased IgG2a level J:142069
decreased IgG2b level J:142069
decreased IgM level J:142069
decreased immature B cell number J:142069
decreased late pro-B cell number J:142069
decreased mature B cell number J:142069
decreased transitional stage B cell number J:142069
increased IgM level J:142069
spleen hypoplasia J:142069
Ightm3Mnz/Ightm4.1Mnz
(involves: C57BL/6)
immune system phenotype J:159173
Ightm3Tim/Igh+
(involves: 129 * C57BL/6)
abnormal B cell differentiation J:102308
abnormal spleen B cell follicle morphology J:102308
Ightm4.1Cog/Ightm4.1Cog
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal class switch recombination J:184094
decreased IgA level J:184094
immune system phenotype J:184094
increased IgM level J:184094
Ightm4.1Fwa/Igh+
(involves: 129S6/SvEvTac)
abnormal B cell differentiation J:176649
abnormal immunoglobulin V(D)J recombination J:176649
Ightm4.1Fwa/Ightm4.1Fwa
(involves: 129S6/SvEvTac)
abnormal B cell differentiation J:176649
abnormal immunoglobulin V(D)J recombination J:176649
Ightm4Cgn/Igh+
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:115292
Ightm4Cog/Igh+
(involves: 129S2/SvPas * C57BL/6)
decreased IgM level J:109988
increased IgA level J:109988
Ightm4Cog/Ightm4Cog
(involves: 129S2/SvPas * C57BL/6)
absent Peyer's patches J:109988
absent spleen germinal center J:109988
small spleen J:109988
Ightm5.1Cgn/Ightm5.1Cgn
(BALB/c-Ightm5.1Cgn)
abnormal B cell activation J:88472
abnormal B cell differentiation J:88472
abnormal gut-associated lymphoid tissue morphology J:88472
abnormal lymph node germinal center morphology J:88472
abnormal mature B cell morphology J:88472
abnormal Peyer's patch germinal center morphology J:88472
absent B-1 B cells J:88472
absent B-1a cells J:88472
absent B-1b cells J:88472
absent spleen germinal center J:88472
decreased B cell number J:88472
decreased immature B cell number J:88472
decreased marginal zone B cell number J:88472
increased pro-B cell number J:88472
Ightm5.1Cog/Ightm5.1Cog
(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:164513
abnormal somatic hypermutation frequency J:164513, J:333348
decreased IgA level J:164513
decreased IgE level J:164513
decreased IgG2b level J:164513
decreased IgG3 level J:164513
decreased IgM level J:164513
Ightm5.1Fwa/Igh+
(involves: 129S6/SvEvTac)
abnormal B cell differentiation J:176649
decreased pre-B cell number J:176649
immune system phenotype J:176649
Ightm5.1Fwa/Ightm5.1Fwa
(involves: 129S6/SvEvTac)
abnormal B cell differentiation J:176649
decreased pre-B cell number J:176649
immune system phenotype J:176649
Ightm5Cgn/Ightm5Cgn
(involves: BALB/c)
absent B cells J:88472
arrested B cell differentiation J:88472
Ightm5Cgn/Ightm5Cgn
Tg(CD19-cre/ERT2)1Cgn/0

(C.Cg-Ightm5Cgn Tg(CD19-cre/ERT2)1Cgn)
abnormal B cell differentiation J:88472
abnormal mature B cell morphology J:88472
abnormal Peyer's patch germinal center morphology J:88472
absent follicular B cells J:88472
absent marginal zone B cells J:88472
increased B cell number J:88472
increased pro-B cell number J:88472
Ightm6Fwa/Ightm6Fwa
(Not Specified)
immune system phenotype J:176649
Ightm7(VHB1-8)Cgn/Igh+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal somatic hypermutation frequency J:48835
Ightm7.1Fwa/Ightm7.1Fwa
(Not Specified)
immune system phenotype J:176649
Ightm8(VHB1-8)Cgn/Igh+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal somatic hypermutation frequency J:48835
Ightm9(VHB1-8)Cgn/Igh+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal somatic hypermutation frequency J:48835
Ightm11.1Cgn/Ightm11.1Cgn
(Not Specified)
abnormal B cell differentiation J:113434
decreased B cell number J:113434
decreased immature B cell number J:113434
decreased mature B cell number J:113434
increased pro-B cell number J:113434
Ightm12Cgn/Ightm12Cgn
(involves: 129P2/OlaHsd)
abnormal somatic hypermutation frequency J:66031
Ighatm1(Myc)Janz/Igha+
(involves: 129S1/Sv * C57BL/6)
increased B cell apoptosis J:90901
increased B cell proliferation J:90901
increased plasma cell number J:90901
Ighatm1(Myc)Janz/Igha+
Tg(Igk-V21-Bax)1967Bvn/0

(involves: 129S1/Sv * C57BL/6 * FVB/N)
abnormal B cell apoptosis J:90901
abnormal plasma cell morphology J:90901
enlarged spleen J:90901
increased IgG level J:90901
increased IgM level J:90901
increased plasma cell number J:90901
Ighatm1(Myc)Janz/Igha+
Tg(Tnfsf13b)1Fma/0

(involves: 129S1/Sv * C57BL/6 * DBA/2J)
enlarged spleen J:166158
increased B cell number J:166158
increased lymphocyte cell number J:166158
increased mature B cell number J:166158
increased spleen white pulp amount J:166158
Ighatm1Grh/Ighatm1Grh
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal dendritic cell physiology J:125472
abnormal immunoglobulin level J:125472
abnormal memory T cell physiology J:125472
abnormal T cell activation J:53217
decreased IgA level J:53217, J:125472
decreased IgE level J:53217
decreased IgG3 level J:53217
decreased interferon-gamma secretion J:53217
decreased T cell proliferation J:125472
immune system phenotype J:53218
increased IgG1 level J:53217, J:125472
increased IgG2a level J:53217
increased IgG2b level J:53217
increased IgG level J:53217
increased IgM level J:53217, J:125472
increased interferon-gamma secretion J:125472
increased interleukin-4 secretion J:53217
increased susceptibility to Orthomyxoviridae infection J:125472
Ighatm1Grh/Ighatm1Grh
(involves: 129 * C57BL/6)
increased susceptibility to parasitic infection J:140515, J:74568
Ighatm1Grh/Ighatm1Grh
Tg(Tnfsf13b)1Fma/Tg(Tnfsf13b)1Fma

(involves: 129S7/SvEvBrd * C57BL/6 * DBA/2)
immune system phenotype J:178227
Ighatm2Grh/Ighatm2Grh
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal class switch recombination J:72521
Ighddmit/Ighddmit
(C57BL/6JAnu-Ighddmit/AnuApb)
abnormal immunoglobulin level J:104190
IghdM1Btlr/Ighd+
(C57BL/6J-IghdM1Btlr)
decreased B cell number J:255202
IghdM1Btlr/IghdM1Btlr
(C57BL/6J-IghdM1Btlr)
decreased B cell number J:255202
decreased IgD level J:255202
Ighdm2Btlr/Ighd+
(C57BL/6J-Ighdm2Btlr)
decreased B cell number J:255203
Ighdm2Btlr/Ighdm2Btlr
(C57BL/6J-Ighdm2Btlr)
decreased B cell number J:255203
decreased IgD level J:255203
Ighdtm1Cgn/Ighdtm1Cgn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune system physiology J:64281
decreased IgE level J:64281
Ighdtm1Lam/Ighd+
(involves: 129S2/SvPas * C57BL/6)
decreased B cell number J:111020
Ighdtm1Lam/Ighdtm1Lam
(involves: 129S2/SvPas * C57BL/6)
abnormal B cell physiology J:111020
abnormal leukopoiesis J:111020
decreased IgG2b level J:111020
increased IgA level J:111020
IgheM1Btlr/IgheM1Btlr
(C57BL/6J-IgheM1Btlr)
decreased IgE level J:267480
Ighg1em1Wliu/Ighg1em1Wliu
(C57BL/6-Ighg1em1Wliu)
abnormal plasma cell differentiation J:266937
enhanced humoral immune response J:266937
increased anti-double stranded DNA antibody level J:266937
increased anti-nuclear antigen antibody level J:266937
increased autoantibody level J:266937
increased germinal center B cell number J:266937
increased IgG1 level J:266937
increased plasma cell number J:266937
Ighg1tm1(cre)Cgn/0
Mef2btm1.1Rdf/Mef2b+

(involves: 129P2/OlaHsd * C57BL/6)
decreased germinal center B cell number J:265465
Ighg1tm1(cre)Cgn/0
Mef2btm1.1Rdf/Mef2btm1.1Rdf

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mature B cell morphology J:265465
decreased germinal center B cell number J:265465
Ighg1tm1(cre)Cgn/0
Mef2btm1.1Rdf/Mef2btm1.1Rdf
Mef2ctm2Eno/Mef2ctm2Eno

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
decreased germinal center B cell number J:265465
Ighg1tm1(cre)Cgn/0
Mef2btm2Rdf/Mef2b+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mature B cell morphology J:265465
increased germinal center B cell number J:265465
Ighg1tm1(cre)Cgn/0
Mef2btm2Rdf/Mef2btm1.1Rdf

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mature B cell morphology J:265465
increased germinal center B cell number J:265465
Ighg1tm1(cre)Cgn/0
Mef2ctm2Eno/Mef2ctm2Eno

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
decreased germinal center B cell number J:265465
Ighg1tm1(cre)Cgn/Ighg1+
Irf4tm1Rdf/Irf4tm1.1Rdf

(involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
abnormal class switch recombination J:112643
abnormal memory B cell morphology J:112643
absent plasma cells J:112643
decreased IgG1 level J:112643
immune system phenotype J:112643
Ighg1tm1(cre)Cgn/Ighg1+
Myd88em1.1Rsky/Myd88+

(involves: 129P2/OlaHsd * C57BL/6NTac)
abnormal somatic hypermutation frequency J:308792
abnormal splenic cell ratio J:308792
increased germinal center B cell number J:308792
increased IgM level J:308792
increased plasma cell number J:308792
Ighg1tm1(cre)Cgn/Ighg1+
Tbl1xr1tm1.1Meln/Tbl1xr1+

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell differentiation J:292118
abnormal spleen morphology J:292118
Ighg1tm1(cre)Cgn/Ighg1+
Tbl1xr1tm1c(EUCOMM)Hmgu/Tbl1xr1tm1c(EUCOMM)Hmgu

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell differentiation J:292118
abnormal spleen morphology J:292118
Ighg1tm1.1Ksho/Ighg1+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:39568
decreased IgG1 level J:39568
Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:39568
decreased IgG1 level J:39568
Ighg1tm1.1Pyu/Ighg1+
(B6.C(Cg)-Ighg1tm1.1Pyu)
decreased IgG1 level J:198154
decreased IgG2c level J:198154
immune system phenotype J:198154
increased IgE level J:198154
increased IgG2a level J:198154
increased susceptibility to type I hypersensitivity reaction J:198154
Ighg1tm1.1Pyu/Ighg1tm1.1Pyu
(B6.C(Cg)-Ighg1tm1.1Pyu)
decreased IgG1 level J:198154
decreased IgG2c level J:198154
immune system phenotype J:198154
increased IgE level J:198154
increased IgG2a level J:198154
increased IgG2b level J:198154
increased susceptibility to type I hypersensitivity reaction J:198154
Ighg1tm1Ksho/Ighg1+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:39568
decreased IgG1 level J:39568
Ighg1tm1Ksho/Ighg1tm1Ksho
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:39568
absent memory B cells J:39568
decreased IgG1 level J:39568
Ighg1tm2Cgn/Ighg1+
((C57BL/6 x 129P2/OlaHsd)F1)
abnormal class switch recombination J:146428
decreased IgG1 level J:146428
Ighg1tm3Cgn/Ighg1+
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal class switch recombination J:166887
decreased IgG1 level J:166887
Ighg1tm4Cgn/Ighg1tm4Cgn
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:166887
Ighmtm1(Bcl6)Rdf/?
(involves: 129/Sv * C57BL/6)
abnormal B cell proliferation J:98937
abnormal spleen B cell follicle morphology J:98937
abnormal spleen morphology J:98937
decreased immunoglobulin level J:98937
decreased plasma cell number J:98937
enlarged spleen J:98937
increased spleen germinal center number J:98937
increased spleen white pulp amount J:98937
Ighmtm1.1(IGH-2)Cog/Ighmtm1.1(IGH-2)Cog
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal B cell differentiation J:157575
abnormal plasma cell differentiation J:157575
decreased B cell number J:157575
decreased B cell proliferation J:157575
decreased B-1 B cell number J:157575
decreased follicular B cell number J:157575
decreased IgA level J:157575
decreased IgG1 level J:157575
decreased IgG2a level J:157575
decreased IgG3 level J:157575
decreased IgG level J:157575
decreased IgM level J:157575
decreased marginal zone B cell number J:157575
decreased mature B cell number J:157575
decreased Peyer's patch number J:157575
decreased pre-B cell number J:157575
decreased transitional stage B cell number J:157575
immune system phenotype J:157575
increased B cell number J:157575
increased B cell proliferation J:157575
increased plasma cell number J:157575
increased pro-B cell number J:157575
small lymph nodes J:157575
small Peyer's patches J:157575
Ighmtm1.1Aak/Ighmtm1.1Aak
(involves: 129S2/SvPas * C57BL/6)
abnormal class switch recombination J:171251
decreased B cell number J:171251
decreased pre-B cell number J:171251
immune system phenotype J:171251
increased pro-B cell number J:171251
Ighmtm1Bhe/Ighmtm1Bhe
(C.Cg-Ighmtm1Bhe)
abnormal complement pathway J:177421
abnormal immune serum protein physiology J:177421
impaired complement classical pathway J:177421
Ighmtm1Cgn/Ightm3Tim
(involves: 129 * C57BL/6)
abnormal B cell differentiation J:102308
decreased B cell number J:102308
Ighmtm1Cgn/Ighm+
(NOD.129S2-Ighmtm1Cgn)
increased susceptibility to autoimmune diabetes J:37287
Ighmtm1Cgn/Ighm+
(involves: 129S2/SvPas * C57BL/6)
arrested B cell differentiation J:70398
Ighmtm1Cgn/Ighm+
Tg(Igh-6/Igh-V125)2Jwt/0
Tg(Igk-C/Igk-V125)1Jwt/0

(NOD.Cg-Ighmtm1Cgn Tg(Igh-6/Igh-V125)2Jwt Tg(Igk-C/Igk-V125)1Jwt)
increased susceptibility to autoimmune diabetes J:91865
insulitis J:91865
Ighmtm1Cgn/Ighm+
Tg(Igh-6/Igh-V281)3Jwt/0

(NOD.Cg-Ighmtm1Cgn Tg(Igh-6/Igh-V281)3Jwt)
insulitis J:91865
Ighmtm1Cgn/Ighm+
Tgfb1tm1Doe/Tgfb1tm1Doe

(involves: 129S2/SvPas * C57BL/6 * CF-1)
thymus hypoplasia J:99033
Ighmtm1Cgn/Ighmtm1Cgn
(involves: 129S2/SvPas * C57BL/6)
abnormal B cell differentiation J:64298, J:70398
abnormal lymphatic vessel morphology J:119344
abnormal response to infection J:119344
absent immature B cells J:64298
absent mature B cells J:64298
arrested B cell differentiation J:64298
decreased IgM level J:64298
immune system phenotype J:113083
Ighmtm1Cgn/Ighmtm1Cgn
(NODCaj.129S2-Ighmtm1Cgn)
insulitis J:93190
Ighmtm1Cgn/Ighmtm1Cgn
(NOD.129S2-Ighmtm1Cgn)
decreased susceptibility to autoimmune diabetes J:37287
Ighmtm1Cgn/Ighmtm1Cgn
(B6.129S2-Ighmtm1Cgn/J)
abnormal cytokine secretion J:118565
abnormal humoral immune response J:119584
abnormal spleen morphology J:73100
arrested B cell differentiation J:119584
decreased CD4-positive, alpha-beta T cell number J:73100, J:118565
decreased CD8-positive, alpha-beta T cell number J:73100
decreased dendritic cell number J:73100
decreased IgE level J:125656
decreased IgG1 level J:125656
decreased IgG level J:119584, J:125656
decreased immunoglobulin level J:119584
decreased spleen weight J:73100
immune system phenotype J:73100, J:118565
increased susceptibility to parasitic infection J:74568
Ighmtm1Cgn/Ighmtm1Cgn
(involves: 129S2/SvPas)
abnormal antigen presentation J:112160
abnormal CD4-positive, alpha-beta T cell physiology J:112160
abnormal metallophilic macrophage morphology J:88620
abnormal spleen marginal sinus morphology J:88620
abnormal spleen marginal zone macrophage morphology J:88620
absent follicular dendritic cells J:88620
absent mature B cells J:118453
arrested B cell differentiation J:118453
decreased IgA level J:157450
decreased IgG level J:157450
decreased susceptibility to type IV hypersensitivity reaction J:112160
decreased T cell proliferation J:112160
increased osteoclast cell number J:157619
increased susceptibility to induced arthritis J:157619
increased susceptibility to parasitic infection J:163761
Ighmtm1Cgn/Ighmtm1Cgn
(B6.129S2-Ighmtm1Cgn)
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:126867
Ighmtm1Cgn/Ighmtm1Cgn
(NOD.129S2-Ighmtm1Cgn/DvsJ)
abnormal T cell number J:80859
abnormal T cell proliferation J:80859
absent B cells J:80859
decreased spleen B cell follicle number J:80859
decreased susceptibility to autoimmune diabetes J:80859
Ighmtm1Cgn/Ighmtm1Cgn
Igkctm1Bgmn/Igkctm1Bgmn
Igltm2.1Bgmn/Igltm2.1Bgmn

(involves: 129)
decreased IgG level J:130864
decreased IgM level J:130864
Ighmtm1Cgn/Ighmtm1Cgn
Nlrp1aNeut1/Nlrp1aNeut1

(involves: 129S2/SvPas * C57BL/6)
immune system phenotype J:191055
Ighmtm1Cgn/Ighmtm1Cgn
Tg(Igh-6/Igh-V125)2Jwt/0
Tg(Igk-C/Igk-V125)1Jwt/0

(NOD.Cg-Ighmtm1Cgn Tg(Igh-6/Igh-V125)2Jwt Tg(Igk-C/Igk-V125)1Jwt)
insulitis J:91865
Ighmtm1Cgn/Ighmtm1Cgn
Tg(Igh-6/Igh-V281)3Jwt/0

(NOD.Cg-Ighmtm1Cgn Tg(Igh-6/Igh-V281)3Jwt)
insulitis J:91865
Ighmtm1Cgn/Ighmtm1Cgn
Tg(Igh-VB1-8/Igh-6m)1Mjsk/?

(NODCaj.Cg-Ighmtm1Cgn Tg(Igh-VB1-8/Igh-6m)1Mjsk/FswJ)
increased susceptibility to autoimmune diabetes J:93190
Ighmtm1Cgn/Ighmtm1Cgn
Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg

(NOD.Cg-Ighmtm1Cgn Tg(IghelMD4)4Ccg/DvsJ)
abnormal B lymphocyte antigen presentation J:80859
abnormal mature B cell morphology J:80859
abnormal T cell proliferation J:80859
decreased CD8-positive, alpha-beta T cell number J:80859
decreased susceptibility to autoimmune diabetes J:80859
insulitis J:80859
Ighmtm1Cgn/Ighmtm1Cgn
Tg(TcraR28,TcrbR28)KRNDim/0

(involves: 129S2/SvPas * C57BL/6 * NOD * SJL)
immune system phenotype J:36815
Ighmtm1Cgn/Ighmtm1Cgn
Tgfb1tm1Doe/Tgfb1tm1Doe

(involves: 129S2/SvPas * C57BL/6 * CF-1)
abnormal inflammatory response J:99033
thymus hypoplasia J:99033
Ighmtm1Cgn/Ighmtm1Cgn
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6J)
small intestinal inflammation J:108572
Ighmtm1Cgn/Ighmtm1Cgn
Trex1tm1Tld/Trex1tm1Tld

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
increased inflammatory response J:181257
kidney inflammation J:181257
myocarditis J:181257
tubular nephritis J:181257
Ighmtm1Cgn/Ighmtm1Cgn
X/Yaa

(BXSB.129S2(B6)-Ighmtm1Cgn/Dcr)
decreased susceptibility to systemic lupus erythematosus J:206236
Ighmtm1Che/Ighmtm1Che
(involves: 129S4/SvJae * C57BL/6)
abnormal B cell physiology J:47425
abnormal follicular dendritic cell antigen presentation J:47425
abnormal humoral immune response J:47425
abnormal immune system physiology J:47425
abnormal metallophilic macrophage morphology J:125338
abnormal spleen B cell follicle morphology J:125338
abnormal spleen germinal center morphology J:47425
abnormal spleen marginal zone morphology J:125338
abnormal spleen morphology J:125338
abnormal spleen periarteriolar lymphoid sheath morphology J:125338
abnormal spleen white pulp morphology J:125338
decreased IgG1 level J:47425
decreased IgG2b level J:47425
decreased IgM level J:47425
increased B-1 B cell number J:47425
increased IgA level J:47425
increased IgG2a level J:47425
increased IgG3 level J:47425
Ighmtm1Che/Ighmtm1Che
(involves: 129 * C57BL/6)
increased susceptibility to parasitic infection J:74568
Ighmtm1Fbb/Ighmtm1Fbb
(involves: BALB/cJ)
immune system phenotype J:57600
increased susceptibility to Riboviria infection J:57600
Ighmtm1Msn/Ighm+
(involves: 129S/SvEv)
decreased IgM level J:49405
Ighmtm1Msn/Ighmtm1Msn
(involves: 129S/SvEv)
abnormal B-1a B cell morphology J:49405
abnormal immature B cell morphology J:49405
abnormal mature B cell morphology J:49405
decreased IgG1 level J:49405
decreased IgM level J:49405
increased IgG3 level J:49405
Ighmtm1Msn/Ighmtm1Msn
(involves: 129S/SvEv * C57BL/6)
increased anti-double stranded DNA antibody level J:111817
increased autoantibody level J:111817
kidney inflammation J:111817
Ighmtm1Msn/Ighmtm1Msn
(B6.129S-Ighmtm1Msn)
abnormal B-1a B cell morphology J:80656
abnormal splenic cell ratio J:80656
decreased follicular B cell number J:80656
decreased IgM level J:80656
increased marginal zone B cell number J:80656
Ighmtm1Msn/Ighmtm1Msn
Tg(Igh-6)1Msn/?

(B6.129S-Ighmtm1Msn)
abnormal B-1a B cell morphology J:80656
abnormal splenic cell ratio J:80656
decreased follicular B cell number J:80656
decreased IgM level J:80656
increased marginal zone B cell number J:80656
Ighmtm1Sls/Ighmtm1Sls
(Not Specified)
abnormal class switch recombination J:99465
decreased IgG1 level J:99465
decreased IgG2b level J:99465
decreased IgG3 level J:99465
decreased IgG level J:99465
increased IgM level J:99465
Ighmtm2.1Bgmn/Ighmtm2.1Bgmn
(involves: 129/Sv * C57BL/6 * CBA)
abnormal immune system physiology J:118453
absent mature B cells J:118453
arrested B cell differentiation J:118453
decreased immunoglobulin level J:118453
Ighmtm3Bgmn/Ighmtm3Bgmn
(involves: 129)
abnormal B cell activation J:131633
decreased B cell proliferation J:131633
decreased IgM level J:131633
decreased immature B cell number J:131633
decreased mature B cell number J:131633
increased B-1 B cell number J:131633
Ighmtm3Bgmn/Ighmtm3Bgmn
Igkctm1Bgmn/Igkctm1Bgmn
Igltm2.1Bgmn/Igltm2.1Bgmn

(involves: 129P2/OlaHsd * 129/Sv)
abnormal B cell differentiation J:130864
decreased IgG level J:130864
decreased IgM level J:130864
Ighmtm4Bgmn/Ighmtm4Bgmn
(involves: 129)
abnormal B cell activation J:131633
decreased B cell proliferation J:131633
decreased IgM level J:131633
decreased immature B cell number J:131633
decreased mature B cell number J:131633
increased B-1 B cell number J:131633
Igk-Jtm1.1Lave/Igk-Jtm1.1Lave
(Not Specified)
immune system phenotype J:179317
Igk-Jtm1Cog/Igk-Jtm1.1Cog
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell number J:110100
abnormal plasma cell morphology J:110100
decreased B cell number J:110100
decreased naive B cell number J:110100
immune system phenotype J:110100
increased plasma cell number J:110100
increased pre-B cell number J:110100
Igk-Jtm1Cog/Igk-Jtm1Cog
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:110100
decreased B cell number J:110100
Igk-Jtm1Mwg/Igktm1Dhu
(involves: 129S7/SvEvBrd * C57BL/6)
immune system phenotype J:76116
Igk-Jtm2Mwg/Igktm1Dhu
(involves: 129P2/OlaHsd * 129S7/SvEvBrd)
immune system phenotype J:76116
Igktm1.1(b12)Nemz/Igktm1.1(b12)Nemz
(involves: C57BL/6NTac * FVB/N)
immune system phenotype J:205766
Igktm1Dhu/Igktm1Dhu
Iglc1tm1.1Ust/Iglc1+

(involves: 129S7/SvEvBrd * C57BL/6 * FVB/N)
decreased B cell number J:68144
Igktm1Dhu/Igktm1Dhu
Iglc1tm1.1Ust/Iglc1tm1.1Ust

(involves: 129S7/SvEvBrd * C57BL/6 * FVB/N)
decreased B cell number J:68144
Igktm1Dhu/Igktm1Dhu
Iglc1tm1Ust/Iglc1+

(involves: 129S7/SvEvBrd * C57BL/6)
abnormal B cell differentiation J:68144
increased B cell number J:68144
Igktm1Dhu/Igktm1Dhu
Iglc1tm1Ust/Iglc1tm1Ust

(involves: 129S7/SvEvBrd * C57BL/6)
increased B cell number J:68144
Igktm1Dhu/Igktm1Dhu
Iglc1tm2Ust/Iglc1tm2Ust

(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal B cell differentiation J:74717
decreased B cell number J:74717
decreased immature B cell number J:74717
decreased marginal zone B cell number J:74717
decreased mature B cell number J:74717
decreased transitional stage T1 B cell number J:74717
decreased transitional stage T2 B cell number J:74717
Igktm1Dhu/Igktm1Dhu
Iglc1tm2Ust/Iglc1tm2Ust

(involves: 129S7/SvEvBrd)
increased B-1a cell number J:113218
Igktm1Dhu/Igktm1Dhu
Tg(H2-Ea-HA)HACIIAjca/0
Tg(Tcra/Tcrb)1Vbo/0

(C.Cg-Igktm1Dhu Tg(H2-Ea-HA)HACIIAjca Tg(Tcra/Tcrb)1Vbo)
arthritis J:209872
Igktm1Dhu/Igktm1Dhu
Tg(H2-Ea-HA)HACIIAjca/0
Tg(TcraS106-1,TcrbS106-1)TS1SWAjca/0

(C.Cg-Igktm1Dhu Tg(H2-Ea-HA)HACIIAjca Tg(TcraS106-1,TcrbS106-1)TS1SWAjca)
abnormal CD4-positive, alpha beta T cell morphology J:209872
abnormal lymph node morphology J:209872
abnormal spleen morphology J:209872
absent B cells J:209872
decreased susceptibility to autoimmune disorder J:209872
increased CD4-positive, alpha-beta T cell number J:209872
Igktm1Rsky/Igk+
Igll1tm1Cgn/Igll1tm1Cgn

(involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6)
abnormal B cell differentiation J:35357
decreased B cell number J:35357
decreased immature B cell number J:35357
decreased mature B cell number J:35357
decreased pre-B cell number J:35357
Igktm2Ybgn/Igktm2Ybgn
(Not Specified)
decreased pre-B cell number J:123344
increased immature B cell number J:123344
Igkctm1(IGKC)Mnz/Igkc+
Igk-Jtm1(CD4*)Mss/Igk-J+

(involves: 129S4/SvJae)
abnormal immunoglobulin light chain V-J recombination J:143876
Igkctm1(IGKC)Mnz/Igkc+
Rr158tm1(Igh)Xu/Rr158+

(Not Specified)
abnormal immune system morphology J:124407
decreased B cell number J:124407
Igkctm1(IGKC)Mnz/Rr166tm4.1Wtg
(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
abnormal B cell physiology J:193015
abnormal immunoglobulin level J:193015
Igkctm1Bgmn/Igkctm1Bgmn
(involves: 129P2/OlaHsd)
abnormal B cell number J:28868, J:118712
abnormal humoral immune response J:28868
abnormal Peyer's patch germinal center morphology J:28868
abnormal Peyer's patch morphology J:28868
Igkctm1Bgmn/Igkctm1Bgmn
Igltm1.1Bgmn/Igltm1.1Bgmn

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA)
abnormal immature B cell morphology J:118712
absent B cells J:118712
absent B-1 B cells J:118712
absent B-2 B cells J:118712
decreased B cell number J:118712
spleen hypoplasia J:118712
Igkctm1Bgmn/Igkctm1Bgmn
Igltm1Bgmn/Igltm1Bgmn

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA)
abnormal immature B cell morphology J:118712
absent B-1 B cells J:118712
absent B-2 B cells J:118712
absent mature B cells J:118712
decreased B cell number J:118712
spleen hypoplasia J:118712
Igkctm1Bgmn/Igkctm1Bgmn
Igltm2.1Bgmn/Igltm2.1Bgmn

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA)
absent B cells J:118712
arrested B cell differentiation J:118712
Igkctm1Bgmn/Igkctm1Bgmn
Igltm2.1Bgmn/Igltm2.1Bgmn

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:130864
abnormal immunoglobulin heavy chain V(D)J recombination J:130864
abnormal plasma cell morphology J:130864
decreased IgG level J:130864
decreased IgM level J:130864
Igkctm1Bgmn/Igkctm1Bgmn
Igltm2Bgmn/Igltm2Bgmn

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA)
absent B cells J:118712
arrested B cell differentiation J:118712
Igkctm1Cgn/Igkc+
(involves: C57BL/6)
increased mature B cell number J:64287
Igkctm1Cgn/Igkctm1Cgn
(involves: C57BL/6)
abnormal B cell differentiation J:64287
decreased mature B cell number J:64287
increased immature B cell number J:64287
increased mature B cell number J:64287
spleen hypoplasia J:64287
Igkctm1Jkbv/Igkctm1Jkbv
(Not Specified)
abnormal B cell differentiation J:137738
abnormal immunoglobulin level J:137738
abnormal immunoglobulin light chain V-J recombination J:137738
decreased immature B cell number J:137738
decreased mature B cell number J:137738
increased pre-B cell number J:137738
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGK@yK1)9.2CJkbv/0

(involves: 129P2/OlaHsd)
abnormal immunoglobulin level J:137738
decreased immature B cell number J:137738
decreased mature B cell number J:137738
increased pre-B cell number J:137738
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGK@yK1)9.2CJkbv/Tg(IGK@yK1)9.2CJkbv

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:137738
abnormal immunoglobulin level J:137738
decreased immature B cell number J:137738
decreased mature B cell number J:137738
increased pre-B cell number J:137738
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGK@yK2)J23.1Jkbv/0

(involves: 129P2/OlaHsd)
abnormal B cell morphology J:137738
abnormal immunoglobulin level J:137738
immune system phenotype J:137738
Igkctm1Jkbv/Igkctm1Jkbv
Tg(IGK@yK2)J23.1Jkbv/Tg(IGK@yK2)J23.1Jkbv

(involves: 129P2/OlaHsd)
abnormal B cell morphology J:137738
immune system phenotype J:137738
Igkctm2(IGKC)Cgn/Igkctm2(IGKC)Cgn
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:113008
immune system phenotype J:113008
Igkctm2(IGKC)Cgn/Igkctm2(IGKC)Cgn
Ighg1tm1(IGHG1)Rsky/Ighg1tm1(IGHG1)Rsky

(involves: 129P2/OlaHsd)
immune system phenotype J:127217
Igkrstm1Nemz/Igkrstm1Nemz
(B6.129-Igkrstm1Nemz)
abnormal immunoglobulin light chain V-J recombination J:132125
decreased immature B cell number J:132125
decreased mature B cell number J:132125
Igkrstm1Nemz/Igkrstm1Nemz
Tg(BCL2)22Wehi/?

(involves: 129 * C57BL)
increased anti-double stranded DNA antibody level J:132125
Igkrstm1Nemz/Igkrstm1Nemz
Tg(UBC-scFv)2Nemz/?

(involves: 129 * C57BL/6 * DBA/2)
abnormal B cell clonal deletion J:132125
decreased immature B cell number J:132125
decreased mature B cell number J:132125
Igltm1Cgn/Igltm1Cgn
(involves: C57BL/6)
immune system phenotype J:83289
Iglc1tm1Ust/Iglc1tm1Ust
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal B cell number J:68144
increased lymphocyte cell number J:68144
Iglc1tm2Ust/Iglc1+
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal immunoglobulin light chain V-J recombination J:74717
Iglc1tm2Ust/Iglc1tm2Ust
(involves: 129S7/SvEvBrd)
decreased B cell number J:113218
Iglc1tm2Ust/Iglc1tm2Ust
Ptpn6me-v/Ptpn6me-v

(involves: 129S7/SvEvBrd * C57BL/6J)
decreased B cell number J:113218
Igll1tm1Cgn/Igll1tm1Cgn
(involves: 129S2/SvPas * C57BL/6)
abnormal B cell morphology J:64284
abnormal B-1 B cell number J:64284
abnormal lymphopoiesis J:64284
abnormal pre-B cell morphology J:64284
decreased B cell number J:64284, J:35357
decreased IgG1 level J:64284
decreased IgG2b level J:64284
decreased IgG3 level J:64284
decreased IgG level J:64284
increased pro-B cell number J:64284
spleen hypoplasia J:64284
Igll1tm1Cgn/Igll1tm1Cgn
Tg(Igk-V4CH27)1-2Shc/0

(involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL)
abnormal B cell differentiation J:35357
decreased pre-B cell number J:35357
Igll1tm1Shim/Igll1tm1Shim
Vpreb1atm1Shim/Vpreb1atm1Shim
Vpreb1btm1Shim/Vpreb1btm1Shim

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:76947
decreased B cell number J:76947
decreased B-1a cell number J:76947
decreased immature B cell number J:76947
decreased mature B cell number J:76947
decreased pre-B cell number J:76947
immune system phenotype J:76947
increased late pro-B cell number J:76947
Iglon5em1(IMPC)Mbp/Iglon5em1(IMPC)Mbp
(C57BL/6NCrl-Iglon5em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Ignpq1BALB/cAJcl/Ignpq1HIGA/Nsc
(involves: BALB/cAJcl * HIGA/Nsc)
increased IgA level J:116904
Ignpq1HIGA/Nsc/Ignpq1HIGA/Nsc
(involves: BALB/cAJcl * HIGA/Nsc)
increased IgA level J:116904
Ignpq2BALB/cAJcl/Ignpq2HIGA/Nsc
(involves: BALB/cAJcl * HIGA/Nsc)
increased IgA level J:116904
Ignpq2HIGA/Nsc/Ignpq2HIGA/Nsc
(involves: BALB/cAJcl * HIGA/Nsc)
increased IgA level J:116904
Ignpq3BALB/cAJcl/Ignpq3HIGA/Nsc
(involves: BALB/cAJcl * HIGA/Nsc)
glomerulonephritis J:116904
Ignpq3HIGA/Nsc/Ignpq3HIGA/Nsc
(involves: BALB/cAJcl * HIGA/Nsc)
glomerulonephritis J:116904
Igs2em1(Alb-Golm1)Jdon/Igs2+
(involves: C57BL/6N)
decreased CD8-positive, alpha-beta T cell number J:306528
Igs2tm1(CAG-Ptgs2os)Scrp/Igs2tm1(CAG-Ptgs2os)Scrp
(involves: C57BL/6)
abnormal circulating cytokine level J:325487
increased circulating interleukin-10 level J:325487
Igs2tm1(CAG-Ptgs2os)Scrp/Igs2tm1(CAG-Ptgs2os)Scrp
Ptgs2osem1Scrp/Ptgs2osem1Scrp

(involves: C57BL/6)
immune system phenotype J:325487
Igtpem1Myam/Igtpem1Myam
Irgm1em1Myam/Irgm1em1Myam

(C57BL/6-Irgm1em1Myam Igtpem1Myam)
increased susceptibility to parasitic infection J:308470
Igtpem1Myam/Igtpem1Myam
Irgm1em1Myam/Irgm1em1Myam
Irgm2em2Myam/Irgm2em2Myam

(C57BL/6-Irgm1em1Myam Igtpem1Myam Irgm2em2Myam)
increased susceptibility to parasitic infection J:308470
Igtptm1Gvw/Igtptm1Gvw
(involves: 129S1/Sv * C57BL/6)
immune system phenotype J:59891
increased circulating interferon-gamma level J:59891
increased circulating interleukin-12b level J:59891
increased susceptibility to parasitic infection J:99144, J:59891
Iigp1tm1.1Jcho/Iigp1tm1.1Jcho
(involves: C57BL/6)
increased susceptibility to parasitic infection J:135070
Ikbipem1Bcgen/Ikbipem1Bcgen
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
abnormal cytokine level J:282971
decreased macrophage cytokine production J:282971
increased circulating interleukin-6 level J:282971
increased circulating tumor necrosis factor level J:282971
increased susceptibility to bacterial infection induced morbidity/mortality J:282971
increased susceptibility to induced colitis J:282971
lung inflammation J:282971
Ikbkbem1Macc/Ikbkb+
(involves: C57BL/6NCrl)
abnormal effector T cell number J:290616
abnormal T cell activation J:290616
decreased B cell number J:290616
decreased CD4-positive, alpha-beta T cell number J:290616
decreased CD8-positive, alpha-beta T cell number J:290616
decreased memory B cell number J:290616
decreased T cell number J:290616
increased regulatory T cell number J:290616
Ikbkbem1Macc/Ikbkbem1Macc
(involves: C57BL/6NCrl)
abnormal effector T cell number J:290616
abnormal T cell activation J:290616
decreased B cell number J:290616
decreased CD4-positive, alpha-beta T cell number J:290616
decreased CD8-positive, alpha-beta T cell number J:290616
decreased memory B cell number J:290616
decreased T cell number J:290616
increased regulatory T cell number J:290616
Ikbkbem1Smoc/Ikbkbem1Smoc
(C57BL/6J-Ikbkbem1Smoc)
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:309163
IkbkbM1Btlr/Ikbkb+
(C57BL/6J-IkbkbM1Btlr)
abnormal B cell physiology J:225271
abnormal CD8-positive, alpha-beta T cell differentiation J:225271
abnormal response to infection J:225271
increased response to antigen J:225271
IkbkbM1Btlr/IkbkbM1Btlr
(C57BL/6J-IkbkbM1Btlr)
abnormal B cell physiology J:225271
abnormal CD8-positive, alpha-beta T cell differentiation J:225271
increased susceptibility to viral infection J:225271
IkbkbM2Btlr/IkbkbM2Btlr
(C57BL/6J-IkbkbM2Btlr)
decreased central memory CD4-positive, alpha-beta T cell number J:274802
Ikbkbtm1.1Cgn/Ikbkbtm1.1Cgn
(involves: C57BL/6)
decreased interleukin-6 secretion J:79132, J:85810
Ikbkbtm1Cgn/Ikbkbtm1.1Cgn
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:85810
decreased CD8-positive, alpha-beta T cell number J:85810
decreased single-positive T cell number J:85810
decreased T cell number J:85810
Ikbkbtm1Cgn/Ikbkbtm1Cgn
Il20ratm1Rsab/Il20ratm1Rsab
Tg(KRT14-cre)1Cgn/0

(involves: C57BL/6 * DBA/2)
skin inflammation J:208995
Ikbkbtm1Cgn/Ikbkbtm1Cgn
Il22tm1Jcrd/Il22tm1Jcrd
Tg(KRT14-cre)1Cgn/0

(involves: C57BL/6 * DBA/2)
skin inflammation J:208995
Ikbkbtm1Cgn/Ikbkbtm1Cgn
Il22ra1tm1Rsab/Il22ra1tm1Rsab
Tg(KRT14-cre)1Cgn/0

(involves: C57BL/6 * DBA/2)
skin inflammation J:208995
Ikbkbtm1Cgn/Ikbkbtm1Cgn
Tg(KRT14-cre)1Cgn/0

(involves: C57BL/6 * DBA/2)
skin inflammation J:208995
Ikbkbtm1Cgn/Ikbkbtm1Cgn
Tg(Lck-cre)I57Jxm/0

(involves: C57BL/6 * ICR)
decreased CD4-positive, alpha-beta T cell number J:85810
decreased CD8-positive, alpha-beta T cell number J:85810
Ikbkbtm1Cgn/Ikbkbtm1Cgn
Tnfrsf1atm2Gkl/Tnfrsf1atm2Gkl
Tg(KRT14-cre)1Cgn/0

(involves: 129S/SvEv * C57BL/6 * DBA/2)
skin inflammation J:208995
Ikbkbtm1Lex/Ikbkbtm1Lex
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S/SvEvBrd)
impaired macrophage chemotaxis J:159873
impaired neutrophil chemotaxis J:159873
impaired neutrophil recruitment J:159873
Ikbkbtm2.1Cgn/Ikbkbtm2.1Cgn
(involves: C57BL/6)
decreased interleukin-6 secretion J:79132
Ikbkbtm2Cgn/Ikbkbtm2.1Cgn
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal humoral immune response J:85810
decreased CD4-positive, alpha-beta T cell number J:85810
decreased CD8-positive, alpha-beta T cell number J:85810
decreased IgE level J:85810
Ikbkbtm2Cgn/Ikbkbtm2Cgn
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:85810
decreased memory T cell number J:85810
decreased regulatory T cell number J:85810
Ikbkbtm2Mka/Ikbkbtm2.1Mka
Tg(Vil-cre)1Mka/0

(involves: 129/Sv * C57BL/6)
decreased acute inflammation J:83313
decreased circulating tumor necrosis factor level J:83313
impaired neutrophil recruitment J:83313
Ikbkbtm2Mka/Ikbkbtm2Mka
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129/Sv * 129P2/OlaHsd)
increased macrophage apoptosis J:80159
Ikbketm1Tman/Ikbketm1Tman
(B6.Cg-Ikbketm1Tman)
increased susceptibility to Orthomyxoviridae infection J:119791
lung inflammation J:119791
Ikbkgm1Btlr/Y
(C57BL/6J-Ikbkgm1Btlr)
decreased regulatory T cell number J:139558
decreased tumor necrosis factor secretion J:139558
immune system phenotype J:139558
Ikbkgtm1.1Chtr/Y
Tg(Alb1-cre)7Gsc/0

(involves: C57BL/6 * FVB/N * SJL)
abnormal NK cell physiology J:151485
abnormal NK T cell physiology J:151485
decreased NK cell number J:151485
decreased NK T cell number J:151485
increased interferon-gamma secretion J:151485
liver inflammation J:151485
Ikbkgtm1.1Chtr/Ikbkgtm1.1Chtr
Tg(Alb1-cre)7Gsc/0

(involves: C57BL/6 * FVB/N * SJL)
abnormal NK cell physiology J:151485
abnormal NK T cell physiology J:151485
decreased NK cell number J:151485
decreased NK T cell number J:151485
increased circulating tumor necrosis factor level J:151485
increased interferon-gamma secretion J:151485
liver inflammation J:151485
Ikbkgtm1.1Dwat/Y
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac)
immune system phenotype J:202106
liver inflammation J:202106
Ikbkgtm1.1Dwat/Ikbkg+
(B6.Cg-Ikbkgtm1.1Dwat)
decreased B cell number J:202106
enlarged spleen J:202106
Ikbkgtm1.1Mpa/Y
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:85810
decreased CD8-positive, alpha-beta T cell number J:85810
decreased single-positive T cell number J:85810
decreased T cell number J:85810
increased T cell apoptosis J:85810
Ikbkgtm1.1Mpa/Y
Tg(Vil1-cre)997Gum/0

(B6.Cg-Ikbkgtm1.1Mpa Tg(Vil1-cre)997Gum)
colitis J:175865
Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6)
abnormal B cell differentiation J:113365
decreased B cell number J:113365
decreased mature B cell number J:113365
Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa
Tg(Alb1-cre)7Gsc/0

(involves: C57BL/6 * FVB/N)
abnormal cytokine secretion J:118336
abnormal inflammatory response J:118336
increased susceptibility to endotoxin shock J:137861
liver inflammation J:118336
Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa
Tg(Vil1-cre)997Gum/0

(B6.Cg-Ikbkgtm1.1Mpa Tg(Vil1-cre)997Gum)
colitis J:175865
Ikbkgtm1Dwb/Ikbkgtm1Dwb
(Not Specified)
abnormal chemokine secretion J:136353
abnormal humoral immune response J:136353
decreased interleukin-6 secretion J:136353
decreased interleukin-12b secretion J:136353
decreased susceptibility to endotoxin shock J:136353
decreased tumor necrosis factor secretion J:136353
Ikbkgtm1Mak/Y
(involves: 129P2/OlaHsd * C57BL/6)
increased interleukin-6 secretion J:61666
Ikbkgtm1Mka/Ikbkg+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
erythroderma J:63054
small spleen J:63054
small thymus J:63054
Ikbkgtm1Mpa/Y
(involves: C57BL/6)
decreased interleukin-6 secretion J:63055
decreased tumor necrosis factor secretion J:63055
Ikbkgtm1Mpa/Ikbkg+
(involves: C57BL/6)
skin inflammation J:63055
Ikzf1m1Btlr/Ikzf1m1Btlr
(C57BL/6J-Ikzf1m1Btlr)
abnormal natural killer cell mediated cytotoxicity J:265249
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:265249
decreased CD8-positive, naive alpha-beta T cell number J:265249
enhanced humoral immune response J:265249
increased B-1 B cell number J:265249
increased CD4-positive, alpha-beta T cell number J:265249
increased CD8-positive, alpha-beta T cell number J:265249
increased central memory CD4-positive, alpha-beta T cell number J:265249
increased central memory CD8 positive, alpha-beta T cell number J:265249
increased effector memory CD4-positive, alpha-beta T cell number J:265249
increased IgG level J:265249
increased response to antigen J:265249
increased single-positive T cell number J:265249
increased T cell number J:265249
Ikzf1m2Btlr/Ikzf1m2Btlr
(C57BL/6J-Ikzf1m2Btlr)
decreased B cell number J:265250
decreased CD4-positive, alpha-beta T cell number J:265250
decreased CD8-positive, naive alpha-beta T cell number J:265250
decreased single-positive T cell number J:265250
decreased T cell number J:265250
increased CD8-positive, alpha-beta T cell number J:265250
increased central memory CD4-positive, alpha-beta T cell number J:265250
increased central memory CD8 positive, alpha-beta T cell number J:265250
increased effector memory CD4-positive, alpha-beta T cell number J:265250
increased effector memory CD8-positive, alpha-beta T cell number J:265250
increased single-positive T cell number J:265250
Ikzf1m3Btlr/Ikzf1m3Btlr
(C57BL/6J-Ikzf1m3Btlr)
decreased CD4-positive, alpha-beta T cell number J:265251
increased B-1 B cell number J:265251
increased CD8-positive, alpha-beta T cell number J:265251
increased single-positive T cell number J:265251
increased T cell number J:265251
Ikzf1plstc/Ikzf1+
(C57BL/6JSfdAnu-Ikzf1plstc)
abnormal B cell differentiation J:84569
abnormal lymphopoiesis J:84569
abnormal T cell differentiation J:84569
decreased double-negative T cell number J:84569
decreased double-positive T cell number J:84569
decreased mature B cell number J:84569
decreased pre-B cell number J:84569
decreased thymocyte number J:84569
increased pro-B cell number J:84569
myeloid hyperplasia J:84569
Ikzf1plstc/Ikzf1plstc
(C57BL/6JSfdAnu-Ikzf1plstc)
abnormal granulocyte differentiation J:84569
abnormal lymphopoiesis J:84569
abnormal macrophage differentiation J:84569
abnormal myelopoiesis J:84569
absent pro-B cells J:84569
absent T cells J:84569
arrested B cell differentiation J:84569
decreased granulocyte number J:84569
increased macrophage cell number J:84569
thymus hypoplasia J:84569
Ikzf1tm1(Pax5)Mbu/Ikzf1tm1(Pax5)Mbu
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell number J:80815
abnormal dendritic cell morphology J:80815
abnormal T cell differentiation J:80815
Ikzf1tm1(Pax5)Mbu/Ikzf1tm1(Pax5)Mbu
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal T cell differentiation J:80815
arrested T cell differentiation J:80815
increased B cell number J:80815
increased early pro-B cell number J:80815
thymus hypoplasia J:80815
Ikzf1tm1.1(Pax5)Mbu/Ikzf1+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:80815
decreased double-positive T cell number J:118111
enlarged lymph nodes J:118111
enlarged spleen J:118111
enlarged thymus J:118111
increased B cell number J:80815
increased pro-B cell number J:80815
thymus hypoplasia J:118111
Ikzf1tm1.1(Pax5)Mbu/Ikzf1+
Tcf3tm1Mbu/Tcf3tm1Mbu
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129P2/OlaHsd * C57BL/10 * CBA/Ca)
abnormal immunoglobulin heavy chain V(D)J recombination J:137719
immune system phenotype J:137719
Ikzf1tm1.1Smale/Ikzf1tm1.1Smale
(B6.Cg-Ikzf1tm1.1Smale)
decreased B cell number J:208211
decreased B-1a cell number J:208211
decreased B-1b cell number J:208211
decreased DN1 thymic pro-T cell number J:208211
decreased immature B cell number J:208211
decreased mature B cell number J:208211
decreased pre-B cell number J:208211
immune system phenotype J:208211
thymus hypoplasia J:208211
Ikzf1tm1Kast/Ikzf1tm1Kast
(involves: 129S2/SvPas)
abnormal B cell activation J:82813
abnormal B cell differentiation J:82813
decreased B cell number J:82813
decreased B cell proliferation J:82813
decreased B-1a cell number J:82813
decreased B-1b cell number J:82813
decreased IgG3 level J:82813
decreased spleen germinal center number J:82813
Ikzf1tm1Kge/Ikzf1+
(involves: 129S4/SvJae * C57BL/6)
abnormal lymph node cortex morphology J:29355
abnormal lymph node medulla morphology J:29355
abnormal T cell differentiation J:29355
abnormal thymocyte activation J:29355
abnormal thymus lobule morphology J:29355
abnormal thymus medulla morphology J:29355
decreased spleen red pulp amount J:29355
enlarged cervical lymph nodes J:29355
enlarged mesenteric lymph nodes J:29355
enlarged thymus J:29355
increased spleen white pulp amount J:29355
increased T cell proliferation J:29355
lymph node hyperplasia J:29355
spleen hyperplasia J:29355
thymus cortex hypoplasia J:29355
Ikzf1tm1Kge/Ikzf1+
(involves: 129S4/SvJae * BALB/c)
abnormal lymph node cortex morphology J:29355
abnormal lymph node medulla morphology J:29355
abnormal T cell differentiation J:29355
abnormal thymocyte activation J:29355
abnormal thymus lobule morphology J:29355
abnormal thymus medulla morphology J:29355
decreased spleen red pulp amount J:29355
enlarged cervical lymph nodes J:29355
enlarged mesenteric lymph nodes J:29355
enlarged thymus J:29355
increased spleen white pulp amount J:29355
increased T cell proliferation J:29355
lymph node hyperplasia J:29355
spleen hyperplasia J:29355
thymus cortex hypoplasia J:29355
Ikzf1tm1Kge/Ikzf1tm1Kge
(involves: 129S4/SvJae * C57BL/6)
abnormal eosinophil morphology J:20671
abnormal immune system organ morphology J:20671
abnormal NK cell morphology J:20671
abnormal spleen morphology J:20671
abnormal thymus cortex morphology J:20671
abnormal thymus morphology J:20671
absent axillary lymph nodes J:20671
absent B cells J:20671
absent cervical lymph nodes J:20671
absent inguinal lymph nodes J:20671
absent mesenteric lymph nodes J:20671
absent Peyer's patches J:20671
absent pre-B cells J:20671
arrested T cell differentiation J:20671
decreased gamma-delta intraepithelial T cell number J:20671
enlarged spleen J:20671
increased basophil cell number J:20671
increased susceptibility to bacterial infection J:20671
intermingled spleen red and white pulp J:20671
lung inflammation J:20671
thymus hypoplasia J:20671
Ikzf1tm1Kge/Ikzf1tm1Kge
(involves: 129S4/SvJae * BALB/c)
abnormal eosinophil morphology J:20671
abnormal immune system organ morphology J:20671
abnormal NK cell morphology J:20671
abnormal spleen morphology J:20671
abnormal thymus cortex morphology J:20671
abnormal thymus morphology J:20671
absent axillary lymph nodes J:20671
absent B cells J:20671
absent cervical lymph nodes J:20671
absent inguinal lymph nodes J:20671
absent mesenteric lymph nodes J:20671
absent Peyer's patches J:20671
absent pre-B cells J:20671
arrested T cell differentiation J:20671
decreased gamma-delta intraepithelial T cell number J:20671
enlarged spleen J:20671
increased basophil cell number J:20671
increased susceptibility to bacterial infection J:20671
intermingled spleen red and white pulp J:20671
lung inflammation J:20671
thymus hypoplasia J:20671
Ikzf1tm2.1Smale/Ikzf1tm2.1Smale
(B6.Cg-Ikzf1tm2.1Smale)
abnormal lymphopoiesis J:208211
abnormal peripheral lymph node morphology J:208211
abnormal T cell differentiation J:208211
absent inguinal lymph nodes J:208211
absent NK cells J:208211
absent Peyer's patches J:208211
decreased B cell number J:208211
decreased DN2 thymocyte number J:208211
decreased DN3 thymocyte number J:208211
decreased double-negative T cell number J:208211
decreased double-positive T cell number J:208211
decreased immature B cell number J:208211
decreased mature B cell number J:208211
decreased plasmacytoid dendritic cell number J:208211
decreased pre-pro B cell number J:208211
immune system phenotype J:208211
increased gamma-delta T cell number J:208211
increased pre-B cell number J:208211
thymus cortex hypoplasia J:208211
thymus hypoplasia J:208211
Ikzf1tm2Kge/Ikzf1tm2Kge
(involves: 129S4/SvJae)
abnormal dendritic cell number J:37317
abnormal splenic cell ratio J:37317
abnormal T cell differentiation J:208211, J:37317
abnormal thymus development J:37317
absent axillary lymph nodes J:37317
absent B cells J:208211, J:37317
absent B-1a cells J:37317
absent cervical lymph nodes J:37317
absent inguinal lymph nodes J:37317
absent mesenteric lymph nodes J:37317
absent NK cells J:208211, J:37317
absent Peyer's patches J:37317
absent pre-B cells J:37317
absent pro-B cells J:37317
decreased double-positive T cell number J:37317
decreased gamma-delta intraepithelial T cell number J:37317
decreased granulocyte number J:37317
decreased mature gamma-delta T cell number J:37317
decreased plasmacytoid dendritic cell number J:208211
decreased splenocyte number J:37317
increased T cell proliferation J:37317
thymus hypoplasia J:37317
Ikzf1tm3.1Mbu/Ikzf1tm3.1Mbu
Cd79atm1(cre)Reth/Cd79a+
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL)
decreased pro-B cell number J:209928
Ikzf1tm3Kge/Ikzf1tm3Kge
Tg(CD2-icre)4Kio/?

(involves: C57BL/10 * CBA/Ca)
abnormal B cell physiology J:209927
Ikzf1tm3Kge/Ikzf1tm3Kge
Tg(CD19-cre/ERT2)1Cgn/?

(Not Specified)
abnormal B cell apoptosis J:209927
absent pre-B cells J:209927
decreased pre-B cell number J:209927
Ikzf2tm1.1Etms/Ikzf2tm1.1Etms
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal regulatory T cell physiology J:160098
Ikzf3tm1(KOMP)Vlcg/Ikzf3tm1(KOMP)Vlcg
(C57BL/6N-Ikzf3tm1(KOMP)Vlcg/Rbrc)
decreased large unstained cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Ikzf3tm1Kge/Ikzf3tm1Kge
(involves: 129S4/SvJae * C57BL/6)
abnormal B cell differentiation J:50626
abnormal spleen marginal zone morphology J:50626
abnormal type III hypersensitivity reaction J:81805
autoimmune response J:81805
decreased B cell number J:81805
decreased IgG2b level J:50626
decreased IgG3 level J:50626
decreased IgM level J:50626
decreased naive B cell number J:81805
enlarged spleen J:50626
glomerulonephritis J:81805
increased anti-double stranded DNA antibody level J:81805
increased anti-histone antibody level J:81805
increased anti-nuclear antigen antibody level J:81805
increased anti-single stranded DNA antibody level J:81805
increased autoantibody level J:81805, J:50626
increased B cell proliferation J:50626
increased IgE level J:50626
increased IgG1 level J:50626
increased IgG2a level J:50626
increased pre-B cell number J:50626
increased spleen germinal center number J:50626
increased T cell proliferation J:50626
Ikzf3tm1Kge/Ikzf3tm1Kge
(involves: 129S4/SvJae)
decreased marginal zone B cell number J:69477
increased follicular B cell number J:69477
Ikzf4tm1.1Etms/Ikzf4tm1.1Etms
(Not Specified)
chronic inflammation J:294549
decreased T cell proliferation J:295208
immune system phenotype J:295208
increased susceptibility to experimental autoimmune encephalomyelitis J:295208
Ikzf4tm1Djr/Ikzf4tm1Djr
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
chronic inflammation J:294549
Ikzf5tm1(KOMP)Wtsi/Ikzf5tm1(KOMP)Wtsi
(C57BL/6N-Ikzf5tm1(KOMP)Wtsi/Rbrc)
increased large unstained cell number J:211773
Il1atm1Yiw/Il1atm1Yiw
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased circulating interleukin-1 alpha level J:47429
decreased interleukin-1 beta secretion J:47429
Il1atm1Yiw/Il1atm1Yiw
Il1btm1Yiw/Il1btm1Yiw

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased circulating interleukin-1 alpha level J:47429
decreased circulating interleukin-1 beta level J:47429
decreased susceptibility to experimental autoimmune encephalomyelitis J:165513
decreased susceptibility to type IV hypersensitivity reaction J:165513
Il1atm1Yiw/Il1atm1Yiw
Il1btm1Yiw/Il1btm1Yiw

(involves: 129S1/Sv * 129X1/SvJ * BALB/c)
impaired neutrophil recruitment J:50775
Il1atm1Yiw/Il1atm1Yiw
Il1btm1Yiw/Il1btm1Yiw
Tg(KRT14-CASP1)1Miz/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
dermatitis J:78602
Il1atm1Yiw/Il1atm1Yiw
Nlrp1aNeut1/Nlrp1aNeut1

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal inflammatory response J:191055
increased neutrophil cell number J:191055
Il1btm1Dch/Il1btm1Dch
(involves: 129S2/SvPas)
decreased interleukin-1 beta secretion J:33465
decreased susceptibility to type IV hypersensitivity reaction J:33465
immune system phenotype J:189777
increased susceptibility to bacterial infection J:112400
Il1btm1Lvp/Il1btm1Lvp
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal interleukin-6 secretion J:27234
abnormal lymphocyte physiology J:67001
decreased acute inflammation J:27234
decreased circulating interleukin-1 beta level J:27234
decreased inflammatory response J:27234
decreased interferon-gamma secretion J:67001
decreased interleukin-2 secretion J:67001
decreased interleukin-4 secretion J:67001
decreased susceptibility to experimental autoimmune myasthenia gravis J:67001
Il1btm1Lvp/Il1btm1Lvp
(involves: 129S7/SvEvBrd)
abnormal macrophage physiology J:136368
decreased interleukin-1 beta secretion J:136368
decreased susceptibility to Togaviridae infection J:52841
decreased susceptibility to Togaviridae infection induced morbidity/mortality J:52841
decreased susceptibility to viral infection J:135243
decreased tumor necrosis factor secretion J:82394
increased susceptibility to bacterial infection induced morbidity/mortality J:136368
Il1btm1Lvp/Il1btm1Lvp
(129S7/SvEvBrd-Il1btm1Lvp)
immune system phenotype J:173245
Il1btm1Yiw/Il1btm1Yiw
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased circulating interleukin-1 beta level J:47429
Il1f10tm1Gpa/Il1f10tm1Gpa
(C.129-Il1f10tm1Gpa)
immune system phenotype J:260118
Il1r1em1(IMPC)Ccpcz/Il1r1em1(IMPC)Ccpcz
(C57BL/6NCrl-Il1r1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Il1r1em1Qizh/Il1r1em1Qizh
(C57BL/6-Il1r1em1Qizh)
increased circulating interleukin-6 level J:338375
increased circulating tumor necrosis factor level J:338375
increased susceptibility to induced arthritis J:338375
Il1r1tm1Imx/Il1r1tm1Imx
(involves: 129 * C57BL/6)
decreased circulating interleukin-6 level J:43088
increased susceptibility to bacterial infection J:58851
osteomyelitis J:58851
Il1r1tm1Imx/Il1r1tm1Imx
(involves: 129S7/SvEvBrd)
abnormal neutrophil physiology J:113110
Il1r1tm1Imx/Il1r1tm1Imx
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal neutrophil physiology J:112999
decreased susceptibility to experimental autoimmune uveoretinitis J:115094
Il1r1tm1Imx/Il1r1tm1Imx
(B6.129S7-Il1r1tm1Imx/J)
decreased circulating interleukin-6 level J:125570
decreased circulating interleukin-18 level J:125570
decreased interleukin-6 secretion J:148779, J:125570
decreased tumor necrosis factor secretion J:125570
increased circulating interleukin-1 beta level J:125570
increased circulating interleukin-18 level J:125570
increased susceptibility to bacterial infection J:125570
increased susceptibility to bacterial infection induced morbidity/mortality J:125570
increased susceptibility to induced arthritis J:125570
sepsis J:125570
Il1r1tm1Imx/Il1r1tm1Imx
(B6.129S7-Il1r1tm1Imx)
immune system phenotype J:173245
Il1r1tm1Imx/Il1r1tm1Imx
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx

(involves: 129S7/SvEvBrd * C57BL/6)
abnormal chemokine level J:126652
decreased interleukin-6 secretion J:115094
decreased susceptibility to experimental autoimmune uveoretinitis J:115094
impaired neutrophil recruitment J:126652
increased susceptibility to bacterial infection J:58851
interstitial pneumonia J:126652
lung inflammation J:126652
osteomyelitis J:58851
Il1r1tm1Imx/Il1r1tm1Imx
Vsig4tm1Gne/Vsig4tm1Gne

(B6.Cg-Il1r1tm1Imx Vsig4tm1Gne)
decreased susceptibility to experimental autoimmune encephalomyelitis J:281762
decreased T helper 1 cell number J:281762
decreased T-helper 17 cell number J:281762
increased susceptibility to induced colitis J:281762
Il1r1tm1Quan/Il1r1tm1Quan
(involves: C57BL/6)
abnormal inflammatory response J:219864
abnormal microglial cell activation J:219864
Il1r1tm1Quan/Il1r1tm1Quan
Lyz2tm1(cre)Ifo/Lyz2tm1(cre)Ifo

(involves: 129P2/OlaHsd * C57BL/6)
abnormal inflammatory response J:219864
abnormal microglial cell activation J:219864
Il1r1tm1Quan/Il1r1tm1Quan
Tg(Tek-cre)12Flv/0

(involves: C3H * C57BL/6)
abnormal inflammatory response J:219864
abnormal microglial cell activation J:219864
Il1r1tm1Roml/Il1r1tm1Roml
(involves: 129S1/Sv * C57BL/6)
decreased circulating interleukin-6 level J:42373
decreased circulating serum amyloid protein level J:42373
decreased interleukin-6 secretion J:42373
decreased susceptibility to type IV hypersensitivity reaction J:42373
increased susceptibility to bacterial infection J:42373
Il1r1tm1Roml/Il1r1tm1Roml
(NOD.Cg-Il1r1tm1Roml)
decreased susceptibility to autoimmune diabetes J:87251
Il1r1tm1Roml/Il1r1tm1Roml
(C.Cg-Il1r1tm1Roml)
decreased eosinophil cell number J:82863
decreased immunoglobulin level J:82863
decreased T cell number J:82863
decreased T cell proliferation J:82863
Il1r1tm1Roml/Il1r1tm1Roml
(involves: 129S1/Sv * BALB/c)
impaired neutrophil chemotaxis J:124226
Il1r1tm1Roml/Il1r1tm1Roml
(involves: 129S1/Sv)
decreased neutrophil cell number J:193548
decreased susceptibility to induced arthritis J:120707
Il1r1tm1Roml/Il1r1tm1Roml
Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae

(involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6)
immune system phenotype J:172117
increased interleukin-1 beta secretion J:172117
Il1r1tm1Roml/Il1r1tm1Roml
Nlrp1aNeut1/Nlrp1aNeut1

(involves: 129S1/Sv * C57BL/6)
abnormal leukocyte cell number J:191055
abnormal leukopoiesis J:191055
decreased eosinophil cell number J:191055
decreased lymphocyte cell number J:191055
decreased monocyte cell number J:191055
immune system phenotype J:191055
increased susceptibility to Riboviria infection J:191055
Il1r1tm1Roml/Il1r1tm1Roml
Nlrp3tm1Hhf/Nlrp3+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * C57BL/6)
skin inflammation J:150054
Il1raptm1Roml/Il1raptm1Roml
(involves: 129S1/Sv)
decreased interleukin-6 secretion J:68065
Il1rl1tm1Anjm/Il1rl1tm1Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal eosinophil physiology J:61108
abnormal interleukin secretion J:61108
abnormal T-helper 2 physiology J:61108
decreased interleukin-4 secretion J:61108
decreased interleukin-5 secretion J:61108
granulomatous inflammation J:61108
Il1rl1tm1Anjm/Il1rl1tm1Anjm
(involves: 129P2/OlaHsd)
decreased eosinophil cell number J:159464
decreased IgE level J:159464
Il1rl1tm1Anjm/Il1rl1tm1Anjm
(C.129P2-Il1rl1tm1Anjm)
increased susceptibility to induced pancreatitis J:184801
Il1rl1tm1Brl/Il1rl1tm1Brl
(involves: 129S/SvEv * C57BL/6)
abnormal response to infection J:63507
decreased interleukin-5 secretion J:63507
increased eosinophil cell number J:63507
Il1rl2tm1Hblu/Il1rl2tm1Hblu
(involves: 129 * C57BL/6)
abnormal dendritic cell physiology J:296074
abnormal macrophage activation involved in immune response J:296074
Il1rl2tm1Hblu/Il1rl2tm1Hblu
(involves: 129)
abnormal lymph node morphology J:193548
decreased gamma-delta T cell number J:193548
decreased interleukin-9 secretion J:256437
decreased interleukin-17 secretion J:193548
decreased leukocyte cell number J:193548
decreased macrophage cell number J:193548
decreased neutrophil cell number J:193548
decreased susceptibility to induced colitis J:256437
increased regulatory T cell number J:256437
Il1rntm1.1Cga/Il1rntm1.1Cga
Lyz2tm1(cre)Ifo/Lyz2+

(D1.Cg-Il1rntm1.1Cga Lyz2tm1(cre)Ifo)
abnormal chemokine secretion J:162760
increased interferon-gamma secretion J:162760
increased interleukin-1 beta secretion J:162760
increased interleukin-6 secretion J:162760
increased interleukin-17 secretion J:162760
increased susceptibility to induced arthritis J:162760
increased T cell proliferation J:162760
Il1rntm1Dih/Il1rn+
(involves: 129S/SvEv * C57BL/6J)
decreased susceptibility to bacterial infection J:36387
increased susceptibility to endotoxin shock J:36387
Il1rntm1Dih/Il1rntm1Dih
(involves: 129S/SvEv * C57BL/6J)
decreased circulating interleukin-1 level J:36387
decreased susceptibility to bacterial infection J:36387
increased acute inflammation J:61600, J:88605
increased circulating interleukin-6 level J:61600
increased circulating serum amyloid protein level J:61600
increased susceptibility to endotoxin shock J:36387
Il1rntm1Nick/Il1rn+
(involves: 129P2/OlaHsd * MF1)
aortitis J:59410
Il1rntm1Nick/Il1rntm1Nick
(involves: 129P2/OlaHsd * MF1)
aortitis J:59410
chronic inflammation J:59410
Il1rntm1Nick/Il1rntm1Nick
(involves: 129P2/OlaHsd * MF1 * BALB/cAnNHsd)
aortitis J:89034
immune system phenotype J:89034
skin inflammation J:89034
Il1rntm1Nick/Il1rntm1Nick
(involves: BALB/cAnNHsd)
aortitis J:89034
rheumatoid arthritis J:89034
skin inflammation J:89034
Il1rntm1Nick/Il1rntm1Nick
(involves: C57BL/6)
immune system phenotype J:89034
Il1rntm1Nick/Il1rntm1Nick
(involves: BALB/cAnNHsd * C57BL/6)
aortitis J:89034
immune system phenotype J:89034
rheumatoid arthritis J:89034
Il1rntm1Sush/Il1rntm1Sush
(involves: 129P2/OlaHsd * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:97684
abnormal dendritic cell differentiation J:97684
abnormal dendritic cell number J:97684
abnormal immune system organ morphology J:97684
abnormal T-helper 1 cell morphology J:97684
abnormal T-helper 2 cell morphology J:97684
granulomatous inflammation J:97684
Il1rntm1Yiw/Il1rntm1Yiw
(C.129-Il1rntm1Yiw)
increased interleukin-17 secretion J:143719
rheumatoid arthritis J:143719
Il1rntm1Yiw/Il1rntm1Yiw
Il17atm1Yiw/Il17a+

(involves: 129P2/OlaHsd * BALB/cA * C57BL/6J)
decreased susceptibility to induced arthritis J:83408
Il2m1/Il2m1
(MRL/MpJ)
abnormal T cell activation J:75331
Il2tm1.1Flv/Il2tm1.1Flv
(NOD/ShiLtJ-Il2tm1.1Flv)
abnormal susceptibility to autoimmune disorder J:150823
Il2tm1.1Kasm/Il2tm1.1Kasm
Ndor1Tg(UBC-cre/ERT2)1Ejb/?

(involves: 129S/SvEv * C57BL/6)
decreased circulating interleukin-17 level J:190168
immune system phenotype J:190168
Il2tm1Hor/Il2+
(NOD.129P2(B6)-Il2tm1Hor/DvsJ)
increased susceptibility to autoimmune diabetes J:120349
Il2tm1Hor/Il2tm1Hor
(involves: 129P2/OlaHsd * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:39981, J:39989, J:15573
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:39981, J:15223
abnormal class switch recombination J:15573
abnormal cytotoxic T cell physiology J:39981
abnormal gamma-delta intraepithelial T cell morphology J:15223
abnormal level of surface class II molecules J:15223
abnormal lymphocyte cell number J:15223
abnormal lymphocyte morphology J:37220
abnormal lymphocyte physiology J:15223
abnormal susceptibility to Riboviria infection J:26861
abnormal T-helper 1 cell differentiation J:37220
abnormal thymocyte activation J:37220, J:39989
colitis J:37220, J:29999, J:15223
decreased cytotoxic T cell cytolysis J:15573, J:26198, J:26861
decreased double-negative T cell number J:15223
decreased double-positive T cell number J:37220
decreased splenocyte proliferation J:79241
decreased T cell proliferation J:39989, J:26198
enlarged lymph nodes J:15223
enlarged mesenteric lymph nodes J:29999
enlarged spleen J:15223
impaired natural killer cell mediated cytotoxicity J:15573
increased B cell proliferation J:16662
increased double-negative T cell number J:37220
increased IgA level J:15223
increased IgE level J:16662
increased IgG1 level J:39989, J:15223, J:16662
increased IgG2a level J:16662
increased IgG2b level J:16662
increased length of allograft survival J:26198
increased pre-B cell number J:16662
increased pro-B cell number J:16662
increased single-positive T cell number J:37220
increased T cell proliferation J:15223, J:16662
lymph node hyperplasia J:16662
Il2tm1Hor/Il2tm1Hor
(C.129P2-Il2tm1Hor)
abnormal lymphocyte morphology J:29799
abnormal regulatory T cell physiology J:112603
abnormal spleen morphology J:29799
enlarged lymph nodes J:29799
heart inflammation J:29799
increased B cell proliferation J:29799
increased germinal center B cell number J:29799
increased IgG level J:29799
increased inflammatory response J:29799
increased plasma cell number J:29799
increased spleen red pulp amount J:29799
increased susceptibility to autoimmune hemolytic anemia J:29799
increased T cell proliferation J:29799
liver inflammation J:29799
lung inflammation J:29799
pancreas inflammation J:29799
spleen hyperplasia J:29799
Il2tm1Hor/Il2tm1Hor
(B6.129P2-Il2tm1Hor)
immune system phenotype J:125748
increased activated T cell number J:28924
increased CD4-positive, alpha-beta T cell number J:28924
increased CD8-positive, alpha-beta T cell number J:28924
increased T cell number J:125748
increased T cell proliferation J:28924
Il2tm1Hor/Il2tm1Hor
(C3.129P2-Il2tm1Hor)
increased CD4-positive, alpha-beta T cell number J:28924
increased CD8-positive, alpha-beta T cell number J:28924
Il2tm1Hor/Il2tm1Hor
(B6.129P2-Il2tm1Hor/J)
abnormal circulating cytokine level J:190168
abnormal response to transplant J:113547
abnormal T cell activation J:190168
abnormal T cell proliferation J:190168
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:131774
decreased circulating interferon-gamma level J:190168
decreased circulating interleukin-4 level J:190168
decreased circulating interleukin-13 level J:190168
decreased regulatory T cell number J:113547
enlarged lymph nodes J:113547
increased CD4-positive, alpha-beta T cell number J:131774
increased splenocyte number J:131774
increased susceptibility to autoimmune disorder J:113547
lacrimal gland inflammation J:125129
large intestinal inflammation J:125129
salivary gland inflammation J:125129
Il2tm1Hor/Il2tm1Hor
(involves: 129P2/OlaHsd)
increased regulatory T cell number J:208318
Il2tm1Hor/Il2tm1Hor
(involves: 129P2/OlaHsd * C57BL/6J)
increased circulating interleukin-17 level J:120176
increased T-helper 17 cell number J:120176
Il2tm1Hor/Il2tm1Hor
Il4tm1Cgn/Il4tm1Cgn

(involves: 129P2/OlaHsd * C57BL/6)
abnormal susceptibility to Riboviria infection J:26861
decreased cytotoxic T cell cytolysis J:26861
decreased IgG level J:16662, J:26861
increased B cell proliferation J:16662
increased pre-B cell number J:16662
increased pro-B cell number J:16662
increased T cell proliferation J:16662
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2+

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
colitis J:29999
enlarged mesenteric lymph nodes J:29999
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
immune system phenotype J:29999
Il2tm1Hor/Il2tm1Hor
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra5CC7,Tcrb5CC7)IWep/0

(involves: 129P2/OlaHsd * C57BL/10)
abnormal T cell number J:120176
increased T-helper 17 cell number J:120176
Il2tm1Hor/Il2tm1Hor
Tcrbtm1Mom/Tcrbtm1Mom

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:135589
Il2tm1Hor/Il2tm1Hor
Tg(DO11.10)10Dlo/?

(C.Cg-Il2tm1Hor Tg(DO11.10)10Dlo)
abnormal regulatory T cell physiology J:88349
increased activated T cell number J:88349
increased T cell proliferation J:88349
Il2tm1Hor/Il2tm1Hor
Tg(Pgk1-HA)1.1Vbo/?
Tg(Tcra/Tcrb)1Vbo/?

(C.Cg-Il2tm1Hor Tg(Pgk1-HA)1.1Vbo Tg(Tcra/Tcrb)1Vbo)
abnormal regulatory T cell physiology J:112603
decreased regulatory T cell number J:112603
increased regulatory T cell number J:112603
Il2raM1J/Il2raM1J
(involves: 129S4/SvJae * C57BL/6)
abnormal regulatory T cell physiology J:268677
Il2ratm1b(EUCOMM)Wtsi/Il2ratm1b(EUCOMM)Wtsi
(C57BL/6N-Il2ratm1b(EUCOMM)Wtsi/Orl)
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased large unstained cell number J:211773
increased neutrophil cell number J:211773
Il2ratm1Dw/Il2ratm1Dw
(involves: 129S4/SvJae * C57BL/6)
abnormal B cell physiology J:64279
abnormal lymph organ size J:64279
abnormal T cell morphology J:64279
abnormal T cell physiology J:64279
colitis J:64279
enlarged lymph nodes J:64279
enlarged spleen J:64279
increased IgA level J:64279
increased IgG1 level J:64279
increased IgG2a level J:64279
increased IgG2b level J:64279
increased IgG level J:64279
increased lymphocyte cell number J:64279
increased memory T cell number J:64279
Il2ratm1Dw/Il2ratm1Dw
(B6.129S4-Il2ratm1Dw)
abnormal regulatory T cell physiology J:125748
abnormal T cell activation J:125748
lymphoid hyperplasia J:125748
Il2ratm1Dw/Il2ratm1Dw
(B6.129S4-Il2ratm1Dw/J)
lacrimal gland inflammation J:125129
large intestinal inflammation J:125129
lung inflammation J:125129
salivary gland inflammation J:125129
Il2ratm1Dw/Il2ratm1Dw
Tg(CD2-Ccdc86)1Hfuj/?

(B6.Cg-Il2ratm1Dw Tg(CD2-Ccdc86)1Hfuj)
immune system phenotype J:151722
increased activated T cell number J:151722
Il2ratm1Dw/Il2ratm1Dw
Tg(Pgk1-HA)1.1Vbo/?
Tg(Tcra/Tcrb)1Vbo/?

(C.Cg-Il2ratm1Dw Tg(Pgk1-HA)1.1Vbo Tg(Tcra/Tcrb)1Vbo)
abnormal regulatory T cell physiology J:112603
decreased regulatory T cell number J:112603
increased regulatory T cell number J:112603
Il2rbm1Btlr/Il2rbm1Btlr
(C57BL/6J-Il2rbm1Btlr)
decreased B cell number J:267694
decreased CD4-positive, alpha-beta T cell number J:267694
decreased CD8-positive, naive alpha-beta T cell number J:267694
increased effector memory CD4-positive, alpha-beta T cell number J:267694
increased effector memory CD8-positive, alpha-beta T cell number J:267694
Il2rbm2Btlr/Il2rbm2Btlr
(C57BL/6J-Il2rbm2Btlr)
increased IgE level J:272832
Il2rbM3Btlr/Il2rbM3Btlr
(C57BL/6J-Il2rbM3Btlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:272833
abnormal T cell morphology J:272833
decreased CD8-positive, alpha-beta T cell number J:272833
decreased central memory CD8 positive, alpha-beta T cell number J:272833
decreased NK cell number J:272833
decreased NK T cell number J:272833
increased CD4-positive, alpha-beta T cell number J:272833
increased IgM level J:272833
Il2rbtm1Mak/Il2rbtm1Mak
(either: (involves: 129P2/OlaHsd) or (involves: 129S2/SvPas))
abnormal B cell activation J:25940
abnormal mononuclear cell morphology J:25940
abnormal T cell activation J:25940
decreased B cell number J:25940
decreased double-positive T cell number J:25940
decreased memory T cell number J:25940
enlarged lymph nodes J:25940
enlarged spleen J:25940
increased activated T cell number J:25940
increased anti-nuclear antigen antibody level J:25940
increased CD4-positive, alpha-beta T cell number J:25940
increased CD8-positive, alpha-beta T cell number J:25940
increased granulocyte number J:25940
increased IgE level J:25940
increased IgG1 level J:25940
increased neutrophil cell number J:25940
increased plasma cell number J:25940
increased susceptibility to autoimmune hemolytic anemia J:25940
thymus hypoplasia J:25940
Il2rbtm1Mak/Il2rbtm1Mak
(B6.129-Il2rbtm1Mak)
abnormal lymphocyte morphology J:113547
abnormal response to transplant J:113547
abnormal spleen periarteriolar lymphoid sheath morphology J:113547
abnormal T cell activation J:113547
decreased regulatory T cell number J:113547
decreased T cell proliferation J:113547
enlarged lymph nodes J:113547
enlarged spleen J:113547
increased anti-double stranded DNA antibody level J:113547
increased susceptibility to autoimmune hemolytic anemia J:113547
Il2rbtm1Mak/Il2rbtm1Mak
(C.129-Il2rbtm1Mak)
abnormal immune system organ morphology J:113547
abnormal lymphocyte morphology J:113547
abnormal marginal zone B cell morphology J:113547
abnormal spleen periarteriolar lymphoid sheath morphology J:113547
abnormal T cell activation J:113547
abnormal T cell clonal deletion J:113547
decreased CD8-positive, alpha-beta T cell number J:113547
decreased T cell proliferation J:113547
enlarged lymph nodes J:113547
enlarged spleen J:113547
increased anti-double stranded DNA antibody level J:113547
increased susceptibility to autoimmune hemolytic anemia J:113547
liver inflammation J:113547
Il2rbtm1Mak/Il2rbtm1Mak
(D2.129-Il2rbtm1Mak)
abnormal T cell clonal deletion J:113547
Il2rbtm1Mak/Il2rbtm1Mak
Lcktm1Mak/Lcktm1Mak

(involves: 129)
absent uterine NK cells J:134589
Il2rbtm1Mak/Il2rbtm1Mak
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129 * 129S/SvEv)
decreased NK cell number J:142654
Il2rgtm1.1Asin/Il2rgtm1Wjl
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJae * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:190889
decreased CD8-positive, alpha-beta T cell number J:190889
Il2rgtm1.1Asin/Il2rgtm1Wjl
Tg(Cd8a*-cre)B8Asin/0

(involves: 129S4/SvJae * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:190889
decreased CD8-positive, alpha-beta T cell number J:190889
decreased NK T cell number J:190889
decreased regulatory T cell number J:190889
Il2rgtm1.1Asin/Il2rgtm1Wjl
Tg(Cd8a*-cre)B8Asin/0
Tg(LCKprBCL2)36Sjk/0

(involves: 129S4/SvJae * C57BL/6)
decreased NK T cell number J:190889
Il2rgtm1.1Flv/Y
Rag2tm1.1Flv/Rag2tm1.1Flv

(involves: 129S4/SvJae * BALB/cAnNTac)
abnormal response to transplant J:168303
increased susceptibility to bacterial infection J:168303
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Rag2tm1.1Flv/Rag2tm1.1Flv

(involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac)
abnormal response to transplant J:168302
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv

(involves: 129S4/SvJae * BALB/cAnNTac)
abnormal response to transplant J:168303
increased susceptibility to bacterial infection J:168303
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv

(involves: 129S4/SvJae * BALB/cAnNTac)
abnormal response to transplant J:168301
Il2rgtm1Cgn/Y
(involves: 129 * CB20)
abnormal alpha-beta intraepithelial T cell morphology J:22521
abnormal class switch recombination J:22521
abnormal gamma-delta T cell differentiation J:111821
abnormal leukocyte morphology J:22521
abnormal thymocyte activation J:22521
absent gamma-delta intraepithelial T cell J:111821
absent gamma-delta T cells J:111821
absent NK cells J:22521
absent Peyer's patches J:22521
absent spleen germinal center J:22521
decreased IgE level J:22521
decreased IgM level J:22521
decreased mature B cell number J:22521
decreased plasma cell number J:22521
decreased pre-B cell number J:22521
decreased spleen white pulp amount J:22521
decreased T cell number J:22521
decreased T cell proliferation J:22521
impaired natural killer cell mediated cytotoxicity J:22521
spleen hypoplasia J:22521
thymus hypoplasia J:111821, J:22521
Il2rgtm1Cgn/Y
Rag2tm1Fwa/Rag2tm1Fwa

(B6.129-Rag2tm1Fwa Il2rgtm1Cgn)
absent B cells J:132257
absent NK cells J:132257
absent T cells J:132257
Il2rgtm1Cgn/Il2rgtm1Cgn
(involves: 129 * CB20)
abnormal alpha-beta intraepithelial T cell morphology J:22521
abnormal class switch recombination J:22521
abnormal leukocyte morphology J:22521
abnormal thymocyte activation J:22521
absent NK cells J:22521
absent Peyer's patches J:22521
absent spleen germinal center J:22521
decreased IgE level J:22521
decreased IgM level J:22521
decreased mature B cell number J:22521
decreased plasma cell number J:22521
decreased pre-B cell number J:22521
decreased spleen white pulp amount J:22521
decreased T cell number J:22521
decreased T cell proliferation J:22521
impaired natural killer cell mediated cytotoxicity J:22521
spleen hypoplasia J:22521
thymus hypoplasia J:22521
Il2rgtm1Cgn/Il2rgtm1Cgn
Kittm1.1Bsm/Kittm1.1Bsm

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
arrested T cell differentiation J:90485
Il2rgtm1Cgn/Il2rgtm1Cgn
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129P2/OlaHsd * 129S/SvEv)
abnormal interleukin secretion J:142654
decreased NK cell number J:142654
increased susceptibility to bacterial infection J:142654
Il2rgtm1Krf/Il2rgtm1Krf
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N))
decreased thymocyte number J:114561
Il2rgtm1Krf/Il2rgtm1Krf
Tg(BCL2/IGH)1Tjd/0

(either: (involves: 129P2/OlaHsd * C3H/He * C57BL/6) or (involves: 129P2/OlaHsd * C3H/He * C57BL/6 * FVB/N))
decreased thymocyte number J:114561
Il2rgtm1Krf/Il2rgtm1Krf
Tg(Igh-Pim1)1Brn/0

(either: (involves: 129P2/OlaHsd * C57BL/6 * CBA) or (involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N))
decreased thymocyte number J:114561
Il2rgtm1Sug/Y
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6))
abnormal immune serum protein physiology J:31167
abnormal immune system cell morphology J:31167
abnormal immune system organ morphology J:31167
abnormal immunoglobulin level J:31167
abnormal myelopoiesis J:31167
abnormal splenic cell ratio J:31167
absent NK cells J:31167
absent spleen white pulp J:31167
arrested B cell differentiation J:31167
decreased IgG3 level J:31167
decreased IgG level J:31167
decreased lymphocyte cell number J:31167
decreased T cell number J:31167
decreased thymocyte number J:31167
enlarged Peyer's patches J:31167
enlarged spleen J:31167
increased macrophage cell number J:31167
increased monocyte cell number J:31167
increased neutrophil cell number J:31167
small lymph nodes J:31167
small thymus J:31167
thymus cortex hypoplasia J:31167
thymus hypoplasia J:31167
Il2rgtm1Sug/Il2rgtm1Sug
(B6.129-Il2rgtm1Sug)
absent uterine NK cells J:116952
Il2rgtm1Wjl/Y
(involves: 129S4/SvJae * C57BL/6)
abnormal B cell number J:108209
abnormal basophil physiology J:24117
abnormal CD4-positive, alpha beta T cell morphology J:108209
abnormal cell-mediated immunity J:108209
abnormal gut-associated lymphoid tissue morphology J:24117
abnormal immune serum protein physiology J:108209
abnormal immune system organ morphology J:108209
abnormal lymphocyte morphology J:108209
abnormal mast cell physiology J:24117
abnormal mesenteric lymph node morphology J:24117
abnormal thymocyte activation J:24117
absent gamma-delta intraepithelial T cell J:24117
absent gamma-delta T cells J:24117
absent NK cells J:24117
cecum inflammation J:24117
decreased CD8-positive, alpha-beta T cell number J:24117
decreased double-negative T cell number J:24117
decreased double-positive T cell number J:24117
decreased immature B cell number J:24117
decreased immunoglobulin level J:24117
decreased interferon-gamma secretion J:24117
decreased interleukin-2 secretion J:24117
decreased interleukin-4 secretion J:24117
decreased single-positive T cell number J:24117
decreased T cell proliferation J:24117
impaired natural killer cell mediated cytotoxicity J:24117
small lymph nodes J:24117
small thymus J:24117
small thymus cortex J:24117
spleen hyperplasia J:24117
spleen hypoplasia J:24117
thymus hyperplasia J:108209
Il2rgtm1Wjl/Y
Crlf2tm1Wjl/Crlf2tm1Wjl

(involves: 129S4/SvJae * C57BL/6)
thymus hypoplasia J:108209
Il2rgtm1Wjl/Y
Prkdcscid/Prkdcscid

(NOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz)
abnormal immune system organ morphology J:109833
abnormal response to transplant J:109833, J:140388
abnormal splenic cell ratio J:109833
abnormal thymus morphology J:109833
decreased CD4-positive, alpha-beta T cell number J:109833
decreased CD8-positive, alpha-beta T cell number J:109833
decreased immature B cell number J:109833
decreased immunoglobulin level J:109833
decreased leukocyte cell number J:109833
decreased mature B cell number J:109833
decreased NK cell number J:109833
decreased spleen B cell follicle number J:109833
lymph node hypoplasia J:109833
small lymph nodes J:109833
Il2rgtm1Wjl/Y
Rag1tm1Mom/Rag1tm1Mom

(NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl/SzJ)
abnormal adaptive immunity J:140388
abnormal innate immunity J:140388
abnormal response to transplant J:140388
abnormal spleen morphology J:140388
abnormal thymus morphology J:140388
absent NK T cells J:140388
absent thymus cortex J:140388
absent thymus medulla J:140388
decreased macrophage cell number J:140388
decreased spleen B cell follicle number J:140388
thymus cyst J:140388
Il2rgtm1Wjl/Il2rgtm1Wjl
(B6.129S4-Il2rgtm1Wjl/J)
abnormal dendritic cell physiology J:123902
abnormal splenic cell ratio J:123902
decreased myeloid dendritic cell number J:123902
Il2rgtm1Wjl/Il2rgtm1Wjl
Prkdcscid/Prkdcscid

(NOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz)
abnormal immune system organ morphology J:109833
abnormal response to transplant J:109833
abnormal splenic cell ratio J:109833
abnormal thymus morphology J:109833
decreased CD4-positive, alpha-beta T cell number J:109833
decreased CD8-positive, alpha-beta T cell number J:109833
decreased immature B cell number J:109833
decreased immunoglobulin level J:109833
decreased leukocyte cell number J:109833
decreased mature B cell number J:109833
decreased NK cell number J:109833
decreased spleen B cell follicle number J:109833
lymph node hypoplasia J:109833
small lymph nodes J:109833
thymus cyst J:109833
Il2rgtm1Wjl/Il2rgtm1Wjl
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv * 129S4/SvJae)
abnormal interferon secretion J:140483
absent NK cells J:140483
absent T cells J:140483
increased susceptibility to bacterial infection J:140483
lung inflammation J:140483
Il2rgtm1Wjl/Il2rgtm1Wjl
Tg(CD2-Ccdc86)1Hfuj/?

(B6.Cg-Il2rgtm1Wjl Tg(CD2-Ccdc86)1Hfuj)
decreased CD4-positive, alpha-beta T cell number J:151722
decreased CD8-positive, alpha-beta T cell number J:151722
decreased regulatory T cell number J:151722
decreased splenocyte number J:151722
immune system phenotype J:151722
Il2rgtm2Cgn/Y
Tg(Mx1-cre)1Cgn/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased NK cell number J:132257
Il3tm1Glli/Il3tm1Glli
(either: (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL/6))
abnormal mast cell differentiation J:80500
decreased susceptibility to type IV hypersensitivity reaction J:80640
increased susceptibility to parasitic infection J:80500
Il3tm1Glli/Il3tm1Glli
KitW/KitW-v

(involves: 129S2/SvPas * C57BL/6 * WB)
increased susceptibility to parasitic infection J:80500
Il3ram1/Il3ram1
(A/J)
abnormal leukopoiesis J:23971
Il4/Il13tm3Anjm/Il4/Il13tm3Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune system physiology J:89095
abnormal splenocyte physiology J:72587
abnormal susceptibility to infection J:113543
abnormal T-helper 2 physiology J:89095
decreased IgE level J:113543, J:72587
decreased IgG1 level J:72587
decreased IgG level J:89095
decreased susceptibility to parasitic infection J:72587
granulomatous inflammation J:113543
increased eosinophil cell number J:113543
increased susceptibility to parasitic infection J:113543, J:89095
increased susceptibility to parasitic infection induced morbidity/mortality J:60609
Il4/Il13tm3Anjm/Il4/Il13tm3Anjm
(C.129P2/OlaHsd-Il4/Il13tm3Anjm)
abnormal interleukin-4 secretion J:91403
decreased IgE level J:91403
decreased interferon-gamma secretion J:91403
decreased interleukin-5 secretion J:91403
decreased interleukin-13 secretion J:91403
decreased susceptibility to autoimmune disorder J:91403
increased IgG2a level J:91403
Il4/Il13tm3Anjm/Il4/Il13tm3Anjm
(involves: 129P2/OlaHsd * BALB/c)
abnormal splenocyte physiology J:60609
abnormal susceptibility to infection J:60609, J:131994
decreased IgG1 level J:178986
decreased inflammatory response J:60609, J:165513
ileum inflammation J:60609
increased susceptibility to parasitic infection J:60609
increased susceptibility to parasitic infection induced morbidity/mortality J:60609
Il4/Il13tm3Anjm/Il4/Il13tm3Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune system physiology J:89095
abnormal splenocyte physiology J:72587
abnormal susceptibility to infection J:113543
abnormal T-helper 2 physiology J:89095
decreased IgE level J:113543, J:72587
decreased IgG1 level J:72587
decreased IgG level J:89095
decreased susceptibility to parasitic infection J:72587
granulomatous inflammation J:113543
increased eosinophil cell number J:113543
increased susceptibility to parasitic infection J:113543, J:89095
increased susceptibility to parasitic infection induced morbidity/mortality J:60609
Il4/Il13tm3Anjm/Il4/Il13tm3Anjm
(C.129P2/OlaHsd-Il4/Il13tm3Anjm)
abnormal interleukin-4 secretion J:91403
decreased IgE level J:91403
decreased interferon-gamma secretion J:91403
decreased interleukin-5 secretion J:91403
decreased interleukin-13 secretion J:91403
decreased susceptibility to autoimmune disorder J:91403
increased IgG2a level J:91403
Il4/Il13tm3Anjm/Il4/Il13tm3Anjm
(involves: 129P2/OlaHsd * BALB/c)
abnormal splenocyte physiology J:60609
abnormal susceptibility to infection J:60609, J:131994
decreased IgG1 level J:178986
decreased inflammatory response J:60609, J:165513
ileum inflammation J:60609
increased susceptibility to parasitic infection J:60609
increased susceptibility to parasitic infection induced morbidity/mortality J:60609
Il4tm1(CD2)Irvr/Il4+
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:111440
Il4tm1(CD2)Mmrs/Il4tm1(CD2)Mmrs
(involves: 129)
decreased basophil cell number J:181313
decreased IgE level J:178986
decreased IgG1 level J:178986
decreased interleukin-4 secretion J:181313
Il4tm1.1Wep/Il4+
(C.129P2-Il4tm1.1Wep)
decreased IgE level J:138827
Il4tm1.1Wep/Il4+
Stat6tm1Gru/Stat6tm1Gru

(C.129-Stat6tm1Gru Il4tm1.1Wep)
abnormal T-helper 2 cell differentiation J:138827
decreased IgE level J:138827
impaired eosinophil recruitment J:138827
Il4tm1.1Wep/Il4tm1.1Wep
(involves: 129P2/OlaHsd * C57BL/6)
decreased interleukin-4 secretion J:67964
Il4tm1.1Wep/Il4tm1.1Wep
(C.129P2-Il4tm1.1Wep)
abnormal T-helper 2 cell differentiation J:138827
decreased IgE level J:138827
impaired eosinophil recruitment J:138827
Il4tm1.1Wep/Il4tm1.1Wep
Stat6tm1Gru/Stat6tm1Gru

(C.129-Stat6tm1Gru Il4tm1.1Wep)
abnormal T-helper 2 cell differentiation J:138827
decreased IgE level J:138827
impaired eosinophil recruitment J:138827
Il4tm1Cgn/Il4tm1Cgn
(B6.Cg-Il4tm1Cgn)
abnormal humoral immune response J:89095
abnormal T-helper 2 physiology J:89095
Il4tm1Cgn/Il4tm1Cgn
(NOD.129P2-Il4tm1Cgn)
decreased susceptibility to autoimmune disorder J:95105
increased susceptibility to autoimmune disorder J:95105
Il4tm1Cgn/Il4tm1Cgn
(NOD.Cg-H2b Il4tm1Cgn)
lacrimal gland inflammation J:105803
salivary gland inflammation J:105803
Il4tm1Cgn/Il4tm1Cgn
(involves: 129P2/OlaHsd * NOD)
abnormal cytokine secretion J:85924
decreased IgG1 level J:85924
Il4tm1Cgn/Il4tm1Cgn
(either: NOD.129-Il4tm1Cgn or (involves: 129 * NOD))
autoimmune response J:85924
insulitis J:85924
Il4tm1Cgn/Il4tm1Cgn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:704
decreased IgE level J:704
decreased IgG1 level J:704
granulomatous inflammation J:113543
Il4tm1Cgn/Il4tm1Cgn
(MRL.129P2-Il4tm1Cgn)
lacrimal gland inflammation J:132514
Il4tm1Cgn/Il4tm1Cgn
(B6.129P2-Il4tm1Cgn/J)
immune system phenotype J:160119, J:44346
Il4tm1Cgn/Il4tm1Cgn
(involves: 129P2/OlaHsd * C57BL/6J * MRL/Mp)
decreased IgE level J:39600
decreased IgG1 level J:39600
Il4tm1Cgn/Il4tm1Cgn
(involves: 129P2/OlaHsd * A/WySn * C57BL/10SnSg * Swiss)
decreased IgG1 level J:119207
increased IgG2a level J:119207
Il4tm1Cgn/Il4tm1Cgn
Ndfip1Gt(RRD002)Byg/Ndfip1Gt(RRD002)Byg

(involves: 129P2/OlaHsd)
esophageal inflammation J:205692
increased CD4-positive, alpha-beta T cell number J:205692
increased eosinophil cell number J:205692
increased inflammatory response J:205692
increased interleukin-2 secretion J:205692
increased neutrophil cell number J:205692
increased T cell number J:205692
lung inflammation J:205692
Il4tm1Cgn/Il4tm1Cgn
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(NOD.Cg-Il4tm1Cgn Tg(TcraBDC2.5,TcrbBDC2.5)1Doi)
decreased susceptibility to autoimmune diabetes J:85924
insulitis J:85924
Il4tm1Kopf/Il4tm1Kopf
(involves: 129S2/SvPas * C57BL/6)
abnormal response to infection J:14593
decreased IgE level J:14593
decreased IgG1 level J:14593
decreased interleukin-3 secretion J:14593
decreased interleukin-4 secretion J:14593
decreased interleukin-5 secretion J:14593
decreased interleukin-10 secretion J:14593
increased IgG level J:14593
Il4tm1Kopf/Il4tm1Kopf
(involves: 129S2/SvPas)
decreased eosinophil cell number J:113065
decreased IgE level J:113065
decreased interleukin-5 secretion J:113065
Il4tm1Kopf/Il4tm1Kopf
Lyntm1Ard/Lyntm1Ard

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal circulating complement protein level J:161523
decreased B cell number J:161523
decreased IgE level J:161523
decreased IgG1 level J:161523
increased anti-double stranded DNA antibody level J:161523
increased anti-nuclear antigen antibody level J:161523
increased basophil cell number J:161523
increased IgA level J:161523
increased IgG2a level J:161523
increased IgG2b level J:161523
increased IgM level J:161523
increased mast cell number J:161523
Il4tm1Lky/Il4+
Lattm1.1Mal/Lattm1.1Mal

(involves: 129S2/SvPas * C57BL/6)
abnormal T-helper 2 physiology J:151840
Il4tm1Lky/Il4tm1Lky
Itktm1Litt/Itktm1Litt

(involves: 129S4/SvJae * BALB/c * C57BL/6J)
abnormal cytokine secretion J:129883
abnormal response to infection J:129883
abnormal T-helper 2 physiology J:129883
immune system phenotype J:129883
Il4tm1Nnt/Il4tm1Nnt
(C57BL/6-Il4tm1Nnt/J)
abnormal microglial cell morphology J:125605
abnormal T-helper 2 physiology J:37196
CNS inflammation J:125605
decreased IgE level J:37196
decreased IgG1 level J:37196
decreased IgM level J:37196
decreased interleukin-4 secretion J:37196
decreased interleukin-5 secretion J:37196
decreased interleukin-10 secretion J:120556, J:37196
granulomatous inflammation J:37196
increased IgA level J:37196
increased interferon-gamma secretion J:120556, J:37196
stomach inflammation J:120556
Il4tm1Nnt/Il4tm1Nnt
(involves: C57BL/6)
abnormal interleukin-4 secretion J:91403
decreased susceptibility to autoimmune disorder J:91403
Il4tm1Rao/Il4tm1Rao
(involves: 129S6/SvEvTac * C57BL/6)
abnormal mast cell physiology J:78089
abnormal T-helper 2 physiology J:78089
decreased interleukin-4 secretion J:78089
decreased interleukin-13 secretion J:78089
Il4tm2.1Kubo/Il4tm2.1Kubo
(B6.Cg-Il4tm2.1Kubo)
decreased IgE level J:167446
decreased IgG1 level J:167446
decreased interleukin-4 secretion J:167446
impaired eosinophil recruitment J:167446
increased IgG2c level J:167446
increased interleukin-5 secretion J:167446
increased interleukin-13 secretion J:167446
Il4tm2Nnt/Il4tm2Nnt
(BALB/c-Il4tm2Nnt/J)
abnormal dendritic cell antigen presentation J:141937
abnormal dendritic cell differentiation J:141937
decreased IgE level J:31486
decreased IgG1 level J:31486
decreased interleukin-5 secretion J:141937
decreased interleukin-13 secretion J:141937
decreased susceptibility to autoimmune disorder J:141937
increased interferon-gamma secretion J:141937
Il4tm2Nnt/Il4tm2Nnt
(BALB/c-Il4tm2Nnt)
abnormal splenocyte physiology J:60609
abnormal susceptibility to infection J:60609
ileum inflammation J:60609
increased susceptibility to parasitic infection J:60609
increased susceptibility to parasitic infection induced morbidity/mortality J:60609
Il4tm2Nnt/Il4tm2Nnt
Tgfb1tm1Doe/Tgfb1tm1Doe

(C.Cg-Tgfb1tm1Doe Il4tm2Nnt)
liver inflammation J:69346
Il4tm3.1Kubo/Il4tm3.1Kubo
(B6.Cg-Il4tm3.1Kubo)
decreased interleukin-4 secretion J:167446
Il4ppqNZB/Slc/Il4ppqNZW/Slc
(involves: NZB/Slc * NZW/Slc)
abnormal cytokine secretion J:117863
Il4raM1Btlr/Il4raM1Btlr
(C57BL/6J-Il4raM1Btlr)
decreased IgE level J:267558
Il4raM2Btlr/Il4raM2Btlr
(C57BL/6J-Il4raM2Btlr)
decreased IgE level J:272804
Il4ratm1Fbb/Il4ratm1Fbb
(involves: BALB/c)
abnormal susceptibility to infection J:55526
Il4ratm1Fbb/Il4ratm1Fbb
(involves: BALB/cJ)
abnormal circulating cytokine level J:133518
abnormal circulating interferon-gamma level J:133518
abnormal cytokine secretion J:114751
abnormal immune system physiology J:114751
abnormal macrophage physiology J:114751
decreased T-helper 2 cell number J:172134
granulomatous inflammation J:114751
impaired macrophage chemotaxis J:114751
increased circulating interleukin-4 level J:133518
increased susceptibility to infection J:114751
increased susceptibility to parasitic infection J:114751
liver inflammation J:114751
Il4ratm1Fbb/Il4ratm2Fbb
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * BALB/c)
abnormal immune system physiology J:114751
abnormal macrophage physiology J:114751
decreased susceptibility to parasitic infection J:114751
granulomatous inflammation J:114751
increased susceptibility to parasitic infection J:114751
liver inflammation J:114751
Il4ratm1Sz/Il4ratm1Sz
(BALB/c-Il4ratm1Sz/J)
abnormal microglial cell morphology J:125605
abnormal susceptibility to infection J:131994
abnormal T-helper 2 physiology J:43656
decreased IgE level J:43656
decreased IgG1 level J:43656
decreased interleukin-4 secretion J:43656
decreased interleukin-5 secretion J:43656
decreased interleukin-10 secretion J:43656
increased IgG2a level J:43656
Il4ratm1Sz/Il4ratm1Sz
(BALB/c-Il4ratm1Sz)
increased IgG2a level J:110429
increased susceptibility to parasitic infection J:110429
Il4ratm1Sz/Il4ratm1Sz
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0

(involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:190889
Il4ratm1Tch/Il4ratm1Tch
(involves: 129X1/SvJ * BALB/c)
abnormal immune serum protein physiology J:86215
abnormal T-helper 2 cell morphology J:86215
decreased T cell proliferation J:86215
increased IgE level J:86215
increased IgG level J:86215
respiratory system inflammation J:86215
Il4ratm2Tch/Il4ratm2Tch
(C.129X1-Il4ratm2Tch)
abnormal T-helper 2 physiology J:152376
increased circulating interleukin-4 level J:152376
increased eosinophil cell number J:152376
increased IgE level J:152376
increased monocyte cell number J:152376
increased susceptibility to type I hypersensitivity reaction J:152376
respiratory system inflammation J:152376
Il4ratm2Tch/Il4ratm2Tch
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli/?

(B6.Cg-Il4ratm2Tch Tg(Scgb1a1-rtTA,tetO-IL13)1Eli)
increased eosinophil cell number J:152376
respiratory system inflammation J:152376
Il4ratm3.1Tch/Il4ratm3.1Tch
(C.129X1-Il4ratm3.1Tch)
abnormal macrophage activation involved in immune response J:160806
increased IgE level J:160806
increased interleukin-4 secretion J:160806
increased susceptibility to type I hypersensitivity reaction J:160806
Il5tm1.1(icre)Lky/Il5+
(C57BL/6-Il5tm1.1(icre)Lky)
decreased circulating interleukin-5 level J:206097
Il5tm1Anjm/Il5tm1Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal mast cell morphology J:113543
abnormal mast cell physiology J:113543
abnormal susceptibility to infection J:113543
decreased eosinophil cell number J:113543
decreased IgE level J:113543
granulomatous inflammation J:113543
increased susceptibility to parasitic infection J:113543
Il5tm1Anjm/Il5tm1Anjm
Il9tm1Anjm/Il9tm1Anjm

(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:113543
abnormal interleukin level J:113543
abnormal mast cell morphology J:113543
abnormal mast cell physiology J:113543
abnormal susceptibility to infection J:113543
decreased eosinophil cell number J:113543
decreased IgE level J:113543
granulomatous inflammation J:113543
increased susceptibility to parasitic infection J:113543
Il5tm1Kopf/Il5tm1Kopf
(C57BL/6-Il5tm1Kopf/J)
increased eosinophil cell number J:30867
Il5tm1Kopf/Il5tm1Kopf
(C57BL/6-Il5tm1Kopf)
granulomatous inflammation J:107418
increased interferon-gamma secretion J:107418
increased lymphocyte cell number J:30641
increased neutrophil cell number J:30641
Il5tm1Ktk/Il5+
(B6.129S4-Il5tm1Ktk)
decreased interleukin-5 secretion J:180790
Il5tm1Ktk/Il5tm1Ktk
(B6.129S4-Il5tm1Ktk)
abnormal B-1 B cell morphology J:180790
decreased interleukin-5 secretion J:180790
Il5tm2Anjm/Il5tm2Anjm
Il9tm1Anjm/Il9tm1Anjm

(involves: 129P2/OlaHsd * C57BL/6)
abnormal immunoglobulin level J:113543
abnormal interleukin level J:113543
abnormal susceptibility to infection J:113543
granulomatous inflammation J:113543
increased eosinophil cell number J:113543
increased susceptibility to parasitic infection J:113543
Il5tm3Anjm/Il5tm3Anjm
(involves: 129P2/OlaHsd * C57BL/6)
granulomatous inflammation J:113543
Il5tm3Anjm/Il5tm3Anjm
Il9tm1Anjm/Il9tm1Anjm

(involves: 129P2/OlaHsd * C57BL/6)
granulomatous inflammation J:113543
Il5ratm1Ktk/Il5ratm1Ktk
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:33140
abnormal eosinophil cell number J:33140
abnormal immune system physiology J:33140
abnormal lymphopoiesis J:33140
abnormal T cell differentiation J:33140
decreased CD4-positive, alpha-beta T cell number J:33140
decreased IgA level J:33140
decreased IgG3 level J:33140
decreased IgM level J:33140
decreased immunoglobulin level J:33140
increased susceptibility to parasitic infection J:33140
Il5ratm1Ktk/Il5ratm1Ktk
(B6.129P2-Il5ratm1Ktk)
abnormal B-1 B cell morphology J:89849
decreased B cell proliferation J:89849
decreased B-1 B cell number J:89849
decreased IgA level J:89849
decreased IgG1 level J:89849
decreased IgG3 level J:89849
decreased IgM level J:89849
Il5ratm1Ktk/Il5ratm1Ktk
Lyntm1Tya/Lyntm1Tya

(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune system organ morphology J:91089
abnormal spleen B cell corona morphology J:91089
abnormal spleen white pulp morphology J:91089
decreased B-1 B cell number J:91089
enlarged lymph nodes J:91089
enlarged spleen J:91089
glomerulonephritis J:91089
increased anti-double stranded DNA antibody level J:91089
increased IgA level J:91089
increased IgM level J:91089
increased immunoglobulin level J:91089
Il6tm1.1Jho/Il6tm1.1Jho
Tg(GFAP-cre)8Gtm/0

(involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * CBA)
microgliosis J:211914
Il6tm1Kopf/Il6+
Prdm1tm1Clme/Prdm1tm1Clme
Tg(Itgax-cre)1-1Reiz/0

(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA)
immune system phenotype J:178876
Il6tm1Kopf/Il6+
Tg(ED-L2-IL1RN/IL1B)#Tcw/?

(B6.Cg-Il6tm1Kopf Tg(ED-L2-IL1RN/IL1B)#Tcw)
esophageal inflammation J:180282
Il6tm1Kopf/Il6tm1Kopf
(involves: 129S2/SvPas * C57BL/6)
abnormal acute phase protein level J:17360
abnormal microglial cell morphology J:79142
abnormal T cell differentiation J:17360
decreased cytotoxic T cell cytolysis J:17360
decreased T cell number J:17360
increased susceptibility to bacterial infection J:17360
increased susceptibility to induced colitis J:79073
increased susceptibility to Poxviridae infection J:17360
Il6tm1Kopf/Il6tm1Kopf
(B6.129S2-Il6tm1Kopf/J)
abnormal interleukin-6 secretion J:109359
decreased interferon-gamma secretion J:123351
decreased pro-B cell number J:117320
decreased susceptibility to induced arthritis J:208213
increased interleukin-4 secretion J:123351
Il6tm1Kopf/Il6tm1Kopf
(involves: 129S2/SvPas)
abnormal inflammatory response J:160966
abnormal T cell physiology J:159479
decreased interleukin-17 secretion J:159479
increased susceptibility to bacterial infection induced morbidity/mortality J:161073
Il6tm1Kopf/Il6tm1Kopf
Il6sttm1Ern/Il6sttm1Ern

(involves: 129S1/Sv * 129S2/SvPas)
decreased susceptibility to endotoxin shock J:168781
immune system phenotype J:139226
Il6tm1Kopf/Il6tm1Kopf
Inpp5dtm1Rkh/Inpp5dtm1Rkh

(involves: 129 * C57BL/6)
abnormal lymphopoiesis J:117320
abnormal myelopoiesis J:117320
decreased pro-B cell number J:117320
Il6tm1Kopf/Il6tm1Kopf
Junbtm3Wag/Junbtm3Wag
Tg(KRT5-cre)1Tak/0

(involves: 129/Sv * 129P2/OlaHsd * 129S2/SvPas * C3H * C57BL/6)
immune system phenotype J:155575
skin inflammation J:155575
Il6tm1Kopf/Il6tm1Kopf
Tanktm1Aki/Tanktm1Aki

(involves: 129/Sv * 129S2/SvPas * C57BL/6)
immune system phenotype J:151757
Il6tm1Kopf/Il6tm1Kopf
Tg(ED-L2-IL1RN/IL1B)#Tcw/?

(B6.Cg-Il6tm1Kopf Tg(ED-L2-IL1RN/IL1B)#Tcw)
esophageal inflammation J:180282
Il6tm1Kopf/Il6tm1Kopf
Tg(Rorc-EGFP)1Ebe/?

(involves: 129S2/SvPas * C57BL/6)
abnormal effector T cell morphology J:137020
Il6tm1Mur/Il6tm1Mur
(involves: 129P2/OlaHsd * C57BL/6)
abnormal neutrophil physiology J:25684
immune system phenotype J:25684
increased susceptibility to bacterial infection J:25684
Il6tm1Mur/Il6tm1Mur
(involves: 129/Sv * C57BL/6)
abnormal interferon level J:40579
abnormal lymphocyte cell number J:40579
absent NK cells J:40579
brain inflammation J:40579
increased susceptibility to parasitic infection J:40579
Il6tm1Mur/Il6tm1Mur
(B6.129P2(B6)-Il6tm1Mur)
abnormal inflammatory response J:85581
abnormal microglial cell morphology J:85581
abnormal microglial cell physiology J:85581
abnormal osteoclast differentiation J:65093
abnormal osteoclast physiology J:65093
Il6tm1Poli/Il6tm1Poli
(involves: 129S/SvEv * MF1)
abnormal macrophage physiology J:79314
abnormal neutrophil physiology J:79314
abnormal osteoclast physiology J:17249
abnormal T-helper 1 cell morphology J:79314
abnormal T-helper 1 physiology J:79314
abnormal T-helper 2 physiology J:79314
decreased circulating interleukin-12 level J:79314
decreased IgA level J:79314
decreased IgE level J:79314
immune system phenotype J:17249
increased circulating interleukin-10 level J:79314
increased IgG2a level J:79314
increased susceptibility to fungal infection J:79314
Il6tm1Poli/Il6tm1Poli
(involves: 129S/SvEv * C57BL/6)
decreased inflammatory response J:68063
impaired neutrophil recruitment J:68063
Il6tm1Poli/Il6tm1Poli
(CAnNCrl.129S(Cg)-Il6tm1Poli)
abnormal B cell proliferation J:42869
abnormal immune system physiology J:96706
decreased inflammatory response J:42869
Il6ratm1.1(IL6R)Csk/Il6ratm1.1(IL6R)Csk
(involves: 129S6/SvEvTac * C57BL/6)
abnormal circulating serum amyloid protein level J:207264
Il6ratm1.1(IL6R)Csk/Il6ratm1.1(IL6R)Csk
Tg(H2-L-IL6)40Csk/0

(involves: 129S6/SvEvTac * C57BL/6)
enlarged lymph nodes J:207264
enlarged spleen J:207264
increased plasma cell number J:207264
increased spleen weight J:207264
increased spleen white pulp amount J:207264
Il6ratm1.1Drew/Il6ratm1.1Drew
Lyz2tm1(cre)Ifo/Lyz2+

(involves: C57BL/6 * C57BL/6N * SJL)
immune system phenotype J:160966
Il6ratm1.1Drew/Il6ratm1.1Drew
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: C57BL/6 * C57BL/6N * SJL)
decreased acute inflammation J:160966
Il6ratm1.1Jcbr/Il6ratm1.1Jcbr
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating interleukin-1 beta level J:188445
decreased circulating tumor necrosis factor level J:188445
decreased susceptibility to parasitic infection J:188445
Il6ratm1.1Jcbr/Il6ratm1.1Jcbr
Tg(Alb1-cre)7Gsc/0

(involves: C57BL/6 * FVB/N)
decreased circulating interleukin-1 beta level J:188445
decreased circulating tumor necrosis factor level J:188445
decreased susceptibility to parasitic infection J:188445
increased circulating interleukin-6 level J:166367
increased circulating tumor necrosis factor level J:166367
Il6ratm1.2Drew/Il6ratm1.2Drew
(involves: C57BL/6 * C57BL/6N * FVB/N * SJL)
abnormal inflammatory response J:160966
Il6ratm1.2Jcbr/Il6ratm1.2Jcbr
(involves: C57BL/6)
decreased circulating interleukin-1 beta level J:188445
decreased circulating tumor necrosis factor level J:188445
decreased susceptibility to parasitic infection J:188445
decreased susceptibility to parasitic infection induced morbidity/mortality J:188445
liver inflammation J:202764
Il6ratm1Saj/Il6ratm1Saj
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal CD4-positive, alpha-beta T cell physiology J:159479
Il6sttm1Ard/Il6sttm1Ard
(involves: 129S1/Sv * C57BL/6)
abnormal leukocyte cell number J:110742
abnormal thrombopoiesis J:110742
cecum inflammation J:79555
conjunctivitis J:79555
decreased IgA level J:79555
decreased IgG level J:79555
decreased immunoglobulin level J:79555
increased inflammatory response J:79555
increased susceptibility to induced colitis J:79073
increased susceptibility to parasitic infection J:79555
Il6sttm1Ern/Il6sttm1Ern
(involves: 129S1/Sv * C57BL/6)
abnormal inflammatory response J:139226
decreased susceptibility to induced colitis J:79073
enlarged spleen J:79073
increased osteoclast cell number J:87612
increased susceptibility to induced arthritis J:142883
stomach inflammation J:87206
Il6sttm1Ern/Il6sttm1Ern
(involves: 129S1/Sv)
increased circulating interleukin-6 level J:168781
increased interleukin-6 secretion J:168781
increased neutrophil cell number J:168781
increased susceptibility to endotoxin shock J:168781
Il6sttm1Ern/Il6sttm1Ern
Stat1tm1Rds/Stat1tm1Rds

(involves: 129S1/Sv)
abnormal inflammatory response J:139226
Il6sttm1Ern/Il6sttm1Ern
Stat3tm1Aki/Stat3+

(involves: 129P2/OlaHsd * 129S1/Sv)
decreased circulating interleukin-6 level J:168781
decreased susceptibility to endotoxin shock J:168781
immune system phenotype J:100160, J:142883, J:139226
Il6sttm1Ern/Il6sttm1Ern
Tg(RP11-H2112)5Trme/0

(involves: 129S1/Sv * C57BL/6J * DBA/2J)
abnormal spleen size J:234656
Il6sttm1Ern/Il6sttm1Ern
Tg(RP11-H2112)9Trme/0

(involves: 129S1/Sv * C57BL/6J * DBA/2J)
abnormal spleen size J:234656
Il6sttm1Ern/Il6sttm1Ern
Tiraptm1.1Pjh/Tiraptm1.1Pjh

(involves: 129S1/Sv)
decreased circulating interleukin-6 level J:168781
decreased susceptibility to endotoxin shock J:168781
Il6sttm1Kish/Il6sttm1Kish
(involves: 129P2/OlaHsd * C57BL/6)
thymus hypoplasia J:75419
Il6sttm1Kish/Il6sttm1Kish
(involves: 129P2/OlaHsd * CD-1)
abnormal bone marrow development J:88710
abnormal osteoclast differentiation J:88710
abnormal osteoclast morphology J:88710
abnormal osteoclast physiology J:88710
increased osteoclast cell number J:88710
Il6sttm1Thir/Il6sttm1Thir
(Not Specified)
abnormal B cell physiology J:59922
abnormal dendritic cell antigen presentation J:113335
decreased interleukin-4 secretion J:59922
enlarged axillary lymph nodes J:59922
enlarged cervical lymph nodes J:59922
enlarged inguinal lymph nodes J:59922
enlarged mesenteric lymph nodes J:59922
increased B cell number J:59922
increased CD4-positive, alpha-beta T cell number J:59922
increased CD8-positive, alpha-beta T cell number J:59922
increased IgG2a level J:59922
increased IgG2b level J:59922
increased interferon-gamma secretion J:59922
lymph node hyperplasia J:59922
spleen hyperplasia J:59922
Il6sttm1Thir/Il6sttm1Thir
(involves: 129 * C57BL/6)
abnormal T cell activation J:133059
abnormal T cell clonal deletion J:133059
abnormal thymocyte activation J:133059
decreased double-positive T cell number J:133059
increased activated T cell number J:133059
increased anti-double stranded DNA antibody level J:133059
increased anti-nuclear antigen antibody level J:133059
increased anti-single stranded DNA antibody level J:133059
increased autoantibody level J:133059
increased double-negative T cell number J:133059
increased IgA level J:133059
increased IgG1 level J:133059
increased IgG2a level J:133059
increased IgG2b level J:133059
increased neutrophil cell number J:133059
increased single-positive T cell number J:133059
rheumatoid arthritis J:133059
Il6sttm1Thir/Il6sttm1Thir
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:133059
Il6sttm1Thir/Il6sttm1Thir
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129 * C57BL/6 * DBA)
abnormal negative T cell selection J:133059
Il6sttm1Wme/Il6sttm1Wme
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immunoglobulin level J:67677
abnormal T cell differentiation J:67677
abnormal thrombopoiesis J:67677
decreased thymocyte number J:67677
increased IgE level J:67677
increased IgG level J:67677
increased leukocyte cell number J:67677
Il6sttm2Thir/Il6sttm2Thir
(Not Specified)
abnormal dendritic cell antigen presentation J:113335
decreased B-1a cell number J:59922
decreased IgG1 level J:59922
decreased IgG2a level J:59922
decreased IgG2b level J:59922
decreased interferon-gamma secretion J:59922
increased IgM level J:59922
Il6sttm3Thir/Il6sttm3Thir
(Not Specified)
decreased IgA level J:59922
decreased IgG2a level J:59922
decreased IgG2b level J:59922
Il7hlb368/Il7hlb368
(C57BL/6J-Il7hlb368/J)
abnormal T cell subpopulation ratio J:118450
absent axillary lymph nodes J:118450
absent cervical lymph nodes J:118450
absent mesenteric lymph nodes J:118450
absent Peyer's patches J:118450
absent popliteal lymph nodes J:118450
decreased leukocyte cell number J:82961, J:118450
decreased T cell number J:118450
small inguinal lymph nodes J:118450
small spleen J:118450
small thymus J:118450
spleen hypoplasia J:118450
thymus hypoplasia J:118450
Il7m1Jyen/Il7m1Jyen
(involves: C3H * C57BL/6)
abnormal myeloid leukocyte morphology J:136470
decreased B cell number J:136470
decreased single-positive T cell number J:136470
lymph node hypoplasia J:136470
spleen hypoplasia J:136470
thymus hypoplasia J:136470
Il7tm1.1Mysl/Il7+
(B6.129P2(Cg)-Il7tm1.1Mysl)
decreased T cell number J:200544
small lymph nodes J:200544
Il7tm1.1Mysl/Il7tm1.1Mysl
(B6.129P2(Cg)-Il7tm1.1Mysl)
abnormal mesenteric lymph node morphology J:200544
arrested B cell differentiation J:200544
decreased T cell number J:200544
decreased thymocyte number J:200544
immune system phenotype J:200544
small lymph nodes J:200544
thymus hypoplasia J:200544
Il7tm1Dnax/Il7tm1Dnax
(involves: 129P2/OlaHsd * C57BL/6)
abnormal CD8-positive, alpha beta T cell morphology J:125259
absent lymph nodes J:24165
absent Peyer's patches J:24165
arrested B cell differentiation J:24165
decreased lymphocyte cell number J:24165
decreased spleen weight J:24165
decreased thymus weight J:24165
small spleen J:24165
small thymus J:24165
spleen hypoplasia J:24165
thymus hypoplasia J:24165
Il7tm1Dnax/Il7tm1Dnax
(involves: 129P2/OlaHsd)
decreased thymocyte number J:64861
Il7tm1Dnax/Il7tm1Dnax
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129P2/OlaHsd * 129S/SvEv)
decreased NK cell number J:132257
Il7tm1Hms/Il7tm1Hms
(involves: 129S6/SvEvTac)
spleen hypoplasia J:43971
thymus hypoplasia J:43971
Il7tm2.1Iku/Il7tm2.1Iku
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA)
abnormal B cell differentiation J:190615
abnormal NK T cell physiology J:190615
decreased B cell number J:190615
decreased double-negative T cell number J:190615
decreased lymphocyte cell number J:190615
decreased NK T cell number J:190615
decreased T cell number J:190615
immune system phenotype J:190615
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd4-cre)1Cwi/0

(involves: 129S7/SvEvBrd * C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:190889
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0

(involves: 129S7/SvEvBrd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:190889
Il7rtm1Abra/Il7rtm1Abra
(B6.129S4-Il7rtm1Abra)
abnormal CD4-positive, alpha-beta T cell physiology J:125360
abnormal T cell differentiation J:125360
abnormal T cell proliferation J:125360
decreased B cell number J:125360
decreased CD4-positive, alpha-beta T cell number J:125360
decreased CD8-positive, alpha-beta T cell number J:125360
decreased memory T cell number J:125360
decreased thymocyte number J:125360
increased double-positive T cell number J:125360
Il7rtm1Iku/Il7rtm1Iku
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell differentiation J:34658
abnormal gamma-delta T cell differentiation J:34658
abnormal T cell subpopulation ratio J:34658
absent mature gamma-delta T cells J:34658
absent Peyer's patches J:45633
decreased B-1 B cell number J:34658
decreased double-positive T cell number J:34658
decreased immature B cell number J:34658
decreased leukocyte cell number J:34658
decreased lymphocyte cell number J:34658
decreased mature B cell number J:34658
decreased T cell number J:34658
immune system phenotype J:34658
increased double-negative T cell number J:34658
small thymus J:34658
spleen hypoplasia J:34658
thymus hypoplasia J:34658
Il7rtm1Imx/Il7rtm1Imx
(involves: 129P3/J * 129S7/SvEvBrd)
arrested B cell differentiation J:21135
arrested T cell differentiation J:21135
decreased B cell number J:21135
decreased T cell number J:21135
lymph node hypoplasia J:21135
spleen hypoplasia J:21135
thymus hypoplasia J:21135
Il7rtm1Imx/Il7rtm1Imx
(B6.129S7-Il7rtm1Imx)
abnormal T cell differentiation J:125360
decreased double-positive T cell number J:125360
decreased thymocyte number J:125360
Il7rtm1Imx/Il7rtm1Imx
(involves: 129S7/SvEvBrd)
decreased thymocyte number J:64861
Il7rtm1Imx/Il7rtm1Imx
Tg(Lck-Il7r)1676Trma/?

(involves: 129S7/SvEvBrd * C57BL/6 * SJL)
decreased T cell proliferation J:66400
decreased thymocyte number J:66400
increased thymocyte apoptosis J:66400
Il7rtm2Iku/Il7rtm2Iku
Tg(Cd4-cre)1Cwi/?

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal CD4-positive T cell differentiation J:193283
abnormal CD8-positive, alpha-beta T cell differentiation J:193283
abnormal T cell morphology J:193283
decreased NK T cell number J:193283
increased B cell number J:193283
increased gamma-delta T cell number J:193283
increased thymocyte number J:193283
Il7rtm2Iku/Il7rtm2Iku
Tg(Cd4-cre)1Cwi/?
Tg(H2-K-BCL2)1Josd/?

(involves: 129S6/SvEvTac * C57BL/6 * C3H * DBA/2)
immune system phenotype J:193283
Il9em1(IMPC)Mbp/Il9em1(IMPC)Mbp
(C57BL/6NCrl-Il9em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Il9tm1Anjm/Il9tm1Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal mast cell morphology J:82881
abnormal response to infection J:82881
granulomatous inflammation J:82881, J:113543
increased susceptibility to parasitic infection J:82881
Il9tm1Anjm/Il9tm1Anjm
(involves: C57BL/6)
abnormal cytokine secretion J:115764
immune system phenotype J:115764
Il9tm1Flv/Il9tm1Flv
(BALB/c-Il9tm1Flv)
increased susceptibility to parasitic infection J:208730
Il9rtm1Jcrd/Il9rtm1Jcrd
(involves: C57BL/6)
abnormal regulatory T cell physiology J:151907
immune system phenotype J:115764
increased susceptibility to experimental autoimmune encephalomyelitis J:151907
increased T-helper 1 cell number J:151907
Il10tm1.1Roer/Il10tm1.1Roer
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:94537
abnormal hypersensitivity reaction J:94537
abnormal innate immunity J:94537
increased susceptibility to bacterial infection J:94537
intestinal inflammation J:94537
Il10tm1.1Roer/Il10tm1.1Roer
(involves: 129P2/OlaHsd)
abnormal myeloid leukocyte morphology J:151551
decreased circulating interleukin-10 level J:151551
increased B cell number J:151551
increased myeloid dendritic cell number J:151551
increased plasma cell number J:151551
increased susceptibility to endotoxin shock J:151551
increased T cell number J:151551
spleen hyperplasia J:151551
Il10tm1Cgn/Il10tm1Cgn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine level J:35020
abnormal immune system physiology J:35020
abnormal interferon level J:35020, J:107077, J:125760
abnormal interleukin level J:35020, J:107077, J:51636
abnormal Langerhans cell physiology J:51636
abnormal leukocyte morphology J:35020
abnormal level of surface class II molecules J:15222
abnormal lymphocyte cell number J:35020
abnormal myelopoiesis J:15222
abnormal response to infection J:15222
abnormal tumor necrosis factor level J:107077, J:51636
abnormal type IV hypersensitivity reaction J:35510
cecum inflammation J:35020
chronic inflammation J:15222
colitis J:68476
decreased length of allograft survival J:44346
decreased spleen iron level J:15222
decreased spleen red pulp amount J:15222
decreased T cell proliferation J:125760
immune system phenotype J:107077, J:15222
increased CD4-positive, alpha-beta T cell number J:35020
increased granulocyte number J:35020, J:15222
increased IgE level J:62283
increased IgG1 level J:62283
increased IgG2a level J:62283
increased interferon-gamma secretion J:15222
increased susceptibility to parasitic infection J:123927
increased susceptibility to type IV hypersensitivity reaction J:51636
increased thymus weight J:107077
intestinal inflammation J:35020, J:107077, J:15222
large intestinal inflammation J:35020
small intestinal inflammation J:35020
thymus hyperplasia J:107077
Il10tm1Cgn/Il10tm1Cgn
(involves: 129P2/OlaHsd)
abnormal cytokine secretion J:117122
abnormal inflammatory response J:117122
increased circulating interleukin-12 level J:118833
increased circulating tumor necrosis factor level J:118833
increased susceptibility to endotoxin shock J:117122, J:118833
intestinal inflammation J:113376
Il10tm1Cgn/Il10tm1Cgn
(B6.129P2-Il10tm1Cgn/J)
abnormal chemokine level J:157787
abnormal cytokine level J:157787, J:139972
abnormal regulatory T cell physiology J:125748
cecum inflammation J:157787
increased circulating interferon-gamma level J:157787
increased circulating interleukin-1 alpha level J:157787
increased circulating interleukin-1 beta level J:157787, J:139972
increased circulating interleukin-2 level J:157787
increased circulating interleukin-6 level J:157787, J:139972
increased circulating interleukin-12 level J:157787
increased circulating interleukin-17 level J:157787
increased circulating tumor necrosis factor level J:157787
increased susceptibility to induced colitis J:157787
increased susceptibility to parasitic infection J:157787
large intestinal inflammation J:149347
Il10tm1Cgn/Il10tm1Cgn
(involves: 129P2/OlaHsd * C57BL/6 * DBA/1)
colitis J:84100
Il10tm1Cgn/Il10tm1Cgn
(involves: 129P2/OlaHsd * 129S/SvEv)
colitis J:59872
Il10tm1Cgn/Il10tm1Cgn
(B10.129P2(B6)-Il10tm1Cgn/J)
decreased length of allograft survival J:44346
Il10tm1Cgn/Il10tm1Cgn
(B6.129P2-Il10tm1Cgn)
abnormal circulating interleukin-6 level J:191723
abnormal circulating interleukin-12b level J:191723
Il10tm1Cgn/Il10tm1Cgn
Il4tm1Cgn/Il4tm1Cgn

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T-helper 1 cell differentiation J:111712
increased interferon-gamma secretion J:111712
Il10tm1Cgn/Il10tm1Cgn
Il12btm1Jm/Il12btm1Jm

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
abnormal T-helper 2 cell differentiation J:111712
increased interleukin-13 secretion J:111712
Il10tm1Cgn/Il10tm1Cgn
Il27ratm1Mak/Il27ratm1Mak

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T-helper 1 physiology J:136179
abnormal T-helper 2 physiology J:136179
colitis J:136179
decreased interferon-gamma secretion J:136179
decreased susceptibility to induced colitis J:136179
increased interleukin-13 secretion J:136179
Il10tm1Cgn/Il10tm1Cgn
Nfil3tm1Look/Nfil3tm1Look

(involves: 129P2/OlaHsd * 129X1/SvJ)
colitis J:209365
increased interleukin-12 secretion J:209365
Il10tm1Cgn/Il10tm1Cgn
Nfil3tm1Pbro/Nfil3tm1Pbro

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6)
colitis J:209365
increased interleukin-12 secretion J:209365
Il10tm1Cgn/Il10tm1Cgn
Rps6ka4tm1Jsca/Rps6ka4tm1Jsca
Rps6ka5tm1Jsca/Rps6ka5tm1Jsca

(B6.Cg-Il10tm1Cgn Rps6ka5tm1Jsca Rps6ka4tm1Jsca)
decreased interleukin-10 secretion J:139576
increased interleukin-6 secretion J:139576
increased interleukin-12a secretion J:139576
increased interleukin-12b secretion J:139576
increased tumor necrosis factor secretion J:139576
Il10tm1Cgn/Il10tm1Cgn
Tg(MUC1)79.24Gend/0

(B6.Cg-Il10tm1Cgn Tg(MUC1)79.24Gend)
large intestinal inflammation J:149347
Il10tm1Cgn/Il10tm1Cgn
Tg(Vil1-cre)997Gum/?
Tlr5tm1.1Gewr/Tlr5tm1.1Gewr

(involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NTac * SJL)
colitis J:229155
Il10tm1Cgn/Il10tm1Cgn
Tlr5tm1.1Gewr/Tlr5tm1.1Gewr

(involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NTac)
colitis J:229155
Il10tm1Cgn/Il10tm1Cgn
Vdrtm1Mbd/Vdrtm1Mbd

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:107077
abnormal cytokine level J:107077
abnormal lymph node cell ratio J:107077
abnormal splenic cell ratio J:107077
abnormal thymus corticomedullary boundary morphology J:107077
abnormal thymus involution J:107077
absent spleen white pulp J:107077
colitis J:107077
decreased lymphocyte cell number J:107077
decreased T cell proliferation J:107077
enlarged mesenteric lymph nodes J:107077
enlarged spleen J:107077
increased macrophage cell number J:107077
increased neutrophil cell number J:107077
increased spleen red pulp amount J:107077
increased T cell apoptosis J:107077
intestinal inflammation J:107077
thymus hypoplasia J:107077
Il10tm1Keny/Il10+
Nfil3tm1.1Kubo/Nfil3tm1.1Kubo

(involves: 129 * C57BL/6)
decreased interleukin-10 secretion J:172134
Il10tm1Mhry/Il10tm1Mhry
(involves: 129P2/OlaHsd * C57BL/6)
intestinal inflammation J:117628
Il10tm1Roer/Il10tm1Roer
Foxp3tm4(YFP/icre)Ayr/Y

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal regulatory T cell physiology J:134513
abnormal type IV hypersensitivity reaction J:134513
colitis J:134513
decreased interleukin-10 secretion J:134513
lung inflammation J:134513
Il10tm1Roer/Il10tm1Roer
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal cytokine secretion J:94537
abnormal hypersensitivity reaction J:94537
abnormal lymph node morphology J:94537
increased susceptibility to parasitic infection J:94537
intestinal inflammation J:94537
liver inflammation J:94537
peritoneal inflammation J:94537
Il10tm2Roer/Il10tm2Roer
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:117122
abnormal inflammatory response J:117122
increased susceptibility to endotoxin shock J:117122
Il10tm2Roer/Il10tm2Roer
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal inflammatory response J:117122
increased susceptibility to endotoxin shock J:117122
Il10ram1Jskg/Il10ram1Jskg
(B6.Cg-Il10ram1Jskg)
colitis J:146644
Il10raNZW/Il10ra+
((NZB x NZW)F1)
increased anti-chromatin antibody level J:102087
increased IgG level J:102087
Il10ratm1.1Jack/Il10ratm1.1Jack
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal chemokine level J:157787
abnormal cytokine level J:157787
increased circulating interferon-gamma level J:157787
increased circulating interleukin-1 alpha level J:157787
increased circulating interleukin-1 beta level J:157787
increased circulating interleukin-2 level J:157787
increased circulating interleukin-12 level J:157787
increased circulating interleukin-17 level J:157787
increased circulating tumor necrosis factor level J:157787
increased susceptibility to parasitic infection J:157787
Il10ratm1.1Jack/Il10ratm1.1Jack
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * DBA/2)
immune system phenotype J:157787
Il10ratm1.1Tlg/Il10ratm1.1Tlg
Tg(Cd4-cre)1Cwi/?

(B6.Cg-Tg(Cd4-cre)1Cwi Il10ratm1.1Tlg)
abnormal lymphocyte cell number J:189797
abnormal regulatory T cell number J:189797
autoimmune response J:189797
decreased splenocyte proliferation J:189797
decreased T cell number J:189797
immune system phenotype J:189797
Il10ratm1.2Jack/Il10ratm1.2Jack
(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * DBA/2)
abnormal chemokine level J:157787
abnormal cytokine level J:157787
cecum inflammation J:157787
increased circulating interferon-gamma level J:157787
increased circulating interleukin-1 alpha level J:157787
increased circulating interleukin-1 beta level J:157787
increased circulating interleukin-2 level J:157787
increased circulating interleukin-6 level J:157787
increased circulating interleukin-12 level J:157787
increased circulating interleukin-17 level J:157787
increased circulating tumor necrosis factor level J:157787
increased susceptibility to induced colitis J:157787
increased susceptibility to parasitic infection J:157787
Il10ratm1b(KOMP)Wtsi/Il10ratm1b(KOMP)Wtsi
(C57BL/6N-Il10ratm1b(KOMP)Wtsi/Orl)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Il10rbtm1Agt/Il10rbtm1Agt
(involves: 129S2/SvPas * C57BL/6)
abnormal granulocyte differentiation J:45917
abnormal lymph node medullary cord morphology J:45917
abnormal mesenteric lymph node morphology J:45917
abnormal spleen morphology J:45917
colitis J:134156
increased interferon-gamma secretion J:134156
increased interleukin-17 secretion J:134156
increased leukocyte cell number J:45917
increased spleen weight J:45917
large intestinal inflammation J:45917
spleen hyperplasia J:45917
Il10rbtm1Agt/Il10rbtm1Agt
Tg(Cd4-TGFBR2)16Flv/?

(involves: 129S2/SvPas * C3H * C57BL/6)
abnormal cytokine level J:134156
abnormal cytokine secretion J:134156
colitis J:134156
increased circulating interferon-gamma level J:134156
increased circulating interleukin-6 level J:134156
increased circulating tumor necrosis factor level J:134156
increased interferon-gamma secretion J:134156
increased interleukin-17 secretion J:134156
increased tumor necrosis factor secretion J:134156
liver inflammation J:134156
lung inflammation J:134156
proctitis J:134156
Il11ra1tm1Gos/Il11ra1tm1Gos
(involves: 129S2/SvPas * C57BL/6J)
immune system phenotype J:48920
Il11ra1tm1Gos/Il11ra1tm1Gos
(involves: 129S2/SvPas * C57BL/6J * CD-1)
abnormal NK cell differentiation J:93811
abnormal uterine NK cell morphology J:93811
Il11ra1tm1Wehi/Il11ra1tm1Wehi
(involves: 129S1/Sv * C57BL/6)
immune system phenotype J:42921, J:79073
Il11ra1tm1Wehi/Il11ra1tm1Wehi
Il6tm1Kopf/Il6tm1Kopf

(involves: 129/Sv * C57BL/6)
increased susceptibility to induced colitis J:79073
Il12am1Btlr/Il12am1Btlr
(C57BL/6J-Il12am1Btlr)
increased susceptibility to Herpesvirales infection J:267667
Il12atm1Cab/Il12atm1Cab
(involves: 129S4/SvJae * C57BL/6)
decreased circulating interferon-gamma level J:54482
decreased circulating interleukin-12 level J:54482
Il12atm1Cab/Il12atm1Cab
(B6.129S4-Il12atm1Cab)
abnormal NK cell physiology J:79552
decreased circulating interferon-gamma level J:79552
Il12atm1Cab/Il12atm1Cab
Il23atm1.1Thak/Il23atm1.1Thak

(B6.Cg-Il12atm1Cab Il23atm1.1Thak)
decreased susceptibility to experimental autoimmune encephalomyelitis J:143970
Il12atm1Jm/Il12atm1Jm
(129S1/Sv-Il12atm1Jm)
abnormal CD4-positive, alpha-beta T cell physiology J:34164
decreased susceptibility to type IV hypersensitivity reaction J:34164
increased susceptibility to parasitic infection J:34164
Il12atm1Jm/Il12atm1Jm
(B6.129S1-Il12atm1Jm)
immune system phenotype J:120806
Il12atm1Jm/Il12atm1Jm
(C.129S1-Il12atm1Jm)
impaired natural killer cell mediated cytotoxicity J:125611
Il12atm1Jm/Il12atm1Jm
(involves: 129S1/Sv)
abnormal NK cell physiology J:139001
Il12atm1Jm/Il12atm1Jm
Il12btm1Jm/Il12btm1Jm

(B6.129S1-Il12atm1Jm Il12btm1Jm)
impaired natural killer cell mediated cytotoxicity J:125611
Il12atm1Jm/Il12atm1Jm
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv * 129S1/Sv * 129S6/SvEvTac)
abnormal interferon secretion J:140483
decreased susceptibility to bacterial infection J:140483
lung inflammation J:140483
Il12btm1Jm/Il12btm1Jm
(B6.129S1-Il12btm1Jm/J)
abnormal CD8-positive, alpha-beta T cell physiology J:111568
abnormal granulocyte physiology J:111568
abnormal lymphocyte physiology J:120806
abnormal macrophage physiology J:111568
abnormal NK cell physiology J:120806
decreased circulating interferon-gamma level J:120806
decreased interleukin-17 secretion J:111568
decreased susceptibility to type IV hypersensitivity reaction J:120806
increased susceptibility to bacterial infection J:120806
Il12btm1Jm/Il12btm1Jm
(129S1/Sv-Il12btm1Jm)
abnormal CD4-positive, alpha-beta T cell physiology J:34164
decreased susceptibility to type IV hypersensitivity reaction J:34164
increased susceptibility to parasitic infection J:34164
Il12btm1Jm/Il12btm1Jm
(involves: 129S1/SvImJ)
abnormal T-helper 1 physiology J:46514
decreased interferon-gamma secretion J:46514
impaired natural killer cell mediated cytotoxicity J:46514
Il12btm1Jm/Il12btm1Jm
(involves: 129S1/Sv)
increased susceptibility to bacterial infection induced morbidity/mortality J:161073
Il12btm1Jm/Il12btm1Jm
Il18tm1Aki/Il18tm1Aki

(involves: 129P2/OlaHsd * 129S1/SvImJ)
abnormal T-helper 1 physiology J:46514
decreased interferon-gamma secretion J:46514
impaired natural killer cell mediated cytotoxicity J:46514
Il12btm1Jm/Il12btm1Jm
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv * 129S1/Sv)
abnormal chemokine secretion J:140483
abnormal interferon secretion J:140483
increased susceptibility to bacterial infection J:140483
lung inflammation J:140483
Il12btm1Jm/Il12btm1Jm
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S1/Sv * C57BL/6J)
small intestinal inflammation J:108572
Il12rb1tm1Jm/Il12rb1tm1Jm
(involves: 129S1/Sv * C57BL/6J)
abnormal lymphocyte physiology J:42105
decreased circulating interferon-gamma level J:42105
decreased interferon-gamma secretion J:42105
Il12rb1tm1Jm/Il12rb1tm1Jm
Tg(Rorc-EGFP)1Ebe/?

(involves: 129S1/Sv * C57BL/6)
abnormal effector T cell morphology J:137020
Il12rb2Ifnm-d/Il12rb2Ifnm-d
Tlr4lps-del/Tlr4lps-del

(C57BL/10ScCr)
abnormal dendritic cell physiology J:91014
abnormal granulocyte physiology J:91014
abnormal immune cell physiology J:91014
abnormal macrophage physiology J:91014
abnormal NK cell physiology J:91014
decreased interferon-gamma secretion J:91014, J:70821
increased interleukin-4 secretion J:91014
increased susceptibility to bacterial infection J:91014, J:70821
Il12rb2tm1Jm/Il12rb2tm1Jm
(either: (involves: 129S1/Sv * BALB/cByJ) or (involves: 129S1/Sv * C57BL/6J))
abnormal lymphocyte physiology J:65891
abnormal NK cell physiology J:65891
Il12rb2tm1Jm/Il12rb2tm1Jm
(B6;129S1-Il12rb2tm1Jm/J)
abnormal B cell activation J:106805
abnormal T cell activation J:106805
glomerulonephritis J:106805
increased anti-nuclear antigen antibody level J:106805
increased circulating interleukin-12 level J:120061
increased interleukin-6 secretion J:106805
liver inflammation J:106805
lymphoid hyperplasia J:106805
parotid gland inflammation J:106805
salivary gland inflammation J:106805
submandibular gland inflammation J:106805
Il13tm1(YFP/cre)Lky/Il13+
Il4tm1(CD2)Mmrs/Il4+
Gt(ROSA)26Sortm1(DTA)Lky/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * 129S4/SvJae)
decreased eosinophil cell number J:178986
increased susceptibility to parasitic infection J:178986
Il13tm1.1Anjm/Il13tm1.1Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T-helper 2 cell differentiation J:67965
decreased circulating interleukin-13 level J:67965
decreased IgE level J:67965
decreased interleukin-4 secretion J:67965
decreased interleukin-5 secretion J:67965
decreased interleukin-10 secretion J:67965
decreased T-helper 2 cell number J:67965
increased IgG2b level J:67965
increased IgM level J:67965
increased interferon-gamma secretion J:67965
Il13tm1.1Anjm/Il13tm1.1Anjm
(C.129P2-Il13tm1.1Anjm)
abnormal dendritic cell antigen presentation J:141937
abnormal dendritic cell differentiation J:141937
decreased IgE level J:91403
decreased interleukin-5 secretion J:141937
decreased interleukin-13 secretion J:141937, J:91403
decreased susceptibility to autoimmune disorder J:141937, J:91403
increased IgG2a level J:91403
increased interferon-gamma secretion J:141937
Il13tm1.1Anjm/Il13tm1.1Anjm
Tg(DO11.10)10Dlo/0

(involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:91403
decreased interleukin-13 secretion J:91403
Il13tm1Anjm/Il13+
Il4tm1.1Wep/Il4+

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
decreased interleukin-4 secretion J:69099
Il13tm1Anjm/Il13tm1Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal interleukin secretion J:82881
decreased eosinophil cell number J:82881
decreased interleukin-4 secretion J:82881
decreased interleukin-5 secretion J:82881
decreased interleukin-9 secretion J:82881
granulomatous inflammation J:82881, J:113543
increased susceptibility to parasitic infection J:113543
Il13tm1Anjm/Il13tm1Anjm
(C.129P2-Il13tm1Anjm)
decreased interleukin-4 secretion J:69099
decreased interleukin-13 secretion J:69099
Il13tm1Anjm/Il13tm1Anjm
Il5tm3Anjm/Il5tm3Anjm

(involves: 129P2/OlaHsd * C57BL/6)
granulomatous inflammation J:113543
increased susceptibility to parasitic infection J:113543
Il13tm2Anjm/Il13tm2Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal splenocyte physiology J:72587
abnormal T-helper 2 physiology J:89095
decreased susceptibility to parasitic infection induced morbidity/mortality J:60609
immune system phenotype J:72587
increased susceptibility to parasitic infection J:89095
Il13tm2Anjm/Il13tm2Anjm
(C.129P2(B6)-Il13tm2Anjm)
abnormal response to transplant J:110188
abnormal type I hypersensitivity reaction J:123772
increased length of allograft survival J:110188
increased susceptibility to type I hypersensitivity reaction J:123772
Il13tm2Anjm/Il13tm2Anjm
(involves: 129)
abnormal T-helper 2 cell differentiation J:67965
decreased circulating interleukin-13 level J:67965
decreased IgE level J:67965
decreased interleukin-4 secretion J:67965
decreased interleukin-5 secretion J:67965
decreased interleukin-10 secretion J:67965
decreased T-helper 2 cell number J:67965
increased IgG2b level J:67965
increased IgM level J:67965
increased interferon-gamma secretion J:67965
Il13tm2Anjm/Il13tm2Anjm
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal chemokine level J:131994
abnormal macrophage physiology J:176092
abnormal susceptibility to infection J:131994
decreased susceptibility to bacterial infection J:176092
decreased susceptibility to parasitic infection J:60609
decreased susceptibility to parasitic infection induced morbidity/mortality J:60609
impaired eosinophil recruitment J:126675
impaired neutrophil recruitment J:105813
Il13tm2Anjm/Il13tm2Anjm
(B6.129P2-Il13tm2Anjm)
abnormal antigen presentation J:131969
abnormal leukocyte physiology J:131969
decreased macrophage cell number J:131969
decreased susceptibility to experimental autoimmune encephalomyelitis J:131969
Il13tm3.1Anjm/Il13+
Il1rl1tm1Anjm/Il1rl1tm1Anjm

(involves: 129P2/OlaHsd * BALB/c)
decreased eosinophil cell number J:159464
Il13tm3.1Anjm/Il13+
Il17rbtm1Anjm/Il17rbtm1Anjm

(involves: BALB/c * C57BL/6)
decreased eosinophil cell number J:159464
Il13tm3.1Anjm/Il13+
Il17rbtm1Anjm/Il17rbtm1Anjm
Il1rl1tm1Anjm/Il1rl1tm1Anjm

(involves: 129P2/OlaHsd * BALB/c)
decreased eosinophil cell number J:159464
Il13ra1tm1Twy/Y
(C.Cg-Il13ra1tm1Twy)
abnormal response to infection J:130488
abnormal T-helper 2 physiology J:130488
decreased IgE level J:130488
decreased susceptibility to parasitic infection J:130488
increased CD4-positive, alpha-beta T cell number J:130488
increased circulating interleukin-5 level J:130488
increased eosinophil cell number J:130488
increased IgA level J:130488
increased IgG1 level J:130488
increased IgG3 level J:130488
increased T-helper 2 cell number J:130488
Il13ra1tm1Zagh/Il13ra1tm1Zagh
(involves: BALB/c * C57BL/6)
abnormal thymus development J:183111
impaired myelopoiesis J:183111
Il13ra2tm1Gru/Il13ra2tm1Gru
(C.Cg-Il13ra2tm1Gru)
abnormal macrophage physiology J:82376
decreased circulating interleukin-13 level J:82376
decreased interleukin-4 secretion J:82376
decreased susceptibility to endotoxin shock J:82376
increased IgA level J:82376
increased IgE level J:82376
increased IgG2a level J:82376
increased IgG2b level J:82376
increased interferon-gamma secretion J:82376
increased interleukin-10 secretion J:82376
Il15m1Hwata/Il15m1Hwata
(Not Specified)
abnormal interleukin secretion J:184570
abnormal NK T cell number J:184570
decreased interferon-gamma secretion J:184570
decreased NK cell number J:184570
decreased NK T cell number J:184570
Il15tm1.1Iku/Il15+
(B6.Cg-Il15tm1.1Iku)
immune system phenotype J:206571
Il15tm1Imx/Il15+
Myctm1Atp/Myc+

(involves: 129P2/OlaHsd * C57BL/6)
decreased memory T cell number J:132730
Il15tm1Imx/Il15tm1Imx
(involves: C57BL/6)
abnormal CD8-positive, alpha-beta T cell physiology J:95221
abnormal cytokine secretion J:97620
abnormal immune system morphology J:60915
abnormal immune system physiology J:60915
abnormal lymphocyte morphology J:60915
abnormal susceptibility to infection J:60915
absent uterine NK cells J:84009
decreased CD8-positive, alpha-beta T cell number J:113408, J:60915
decreased CD8-positive, gamma-delta intraepithelial T cell number J:155298
decreased dendritic cell number J:97620
decreased IgG level J:97620
decreased IgM level J:97620
decreased immunoglobulin level J:97620
decreased interferon-gamma secretion J:97620
decreased interleukin-12 secretion J:97620
decreased memory T cell number J:132730
decreased NK cell number J:132730, J:142654, J:60915
decreased regulatory T cell number J:208318
decreased susceptibility to bacterial infection induced morbidity/mortality J:84009
decreased susceptibility to type IV hypersensitivity reaction J:87137
impaired natural killer cell mediated cytotoxicity J:97620
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:97038
increased susceptibility to parasitic infection J:97620
increased susceptibility to Poxviridae infection induced morbidity/mortality J:60915
small lymph nodes J:60915
Il15tm1Imx/Il15tm1Imx
(C57BL/6-Il15tm1Imx)
abnormal dendritic cell physiology J:123902
Il15tm1Imx/Il15tm1Imx
(C57BL/6-Il15tm1Imx/Tac)
abnormal CD8-positive, alpha-beta T cell differentiation J:111786
abnormal thymus cell ratio J:111786
decreased CD8-positive, alpha-beta T cell number J:111786
Il15tm1Imx/Il15tm1Imx
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0

(involves: 129S7/SvEvBrd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:190889
Il15tm1Imx/Il15tm1Imx
Itktm1Litt/Itktm1Litt

(involves: 129S4/SvJae * C57BL/6)
abnormal thymus cell ratio J:111786
Il15tm1Imx/Il15tm1Imx
Itktm1Ljb/Itktm1Ljb

(involves: 129 * C57BL/6 * C57BL/10)
decreased CD8-positive, alpha-beta T cell number J:113408
Il15tm1Imx/Il15tm1Imx
Myctm1Atp/Myc+

(involves: 129P2/OlaHsd * C57BL/6)
decreased memory T cell number J:132730
decreased NK cell number J:132730
Il15tm1Imx/Il15tm1Imx
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv * C57BL/6)
decreased NK cell number J:132257
Il15tm1Imx/Il15tm1Imx
X/Yaa

(BXSB.B6-Il15tm1Imx/Dcr)
increased susceptibility to systemic lupus erythematosus J:179430
Il15ratm1.1Nsl/Il15ratm1.1Nsl
(involves: 129X1/SvJ * C57BL/6)
abnormal T cell apoptosis J:73738
decreased CD8-positive, alpha-beta T cell number J:73738
decreased memory T cell number J:73738
decreased NK cell number J:73738
decreased NK T cell number J:73738
decreased single-positive T cell number J:73738
increased CD4-positive, alpha-beta T cell number J:73738
increased thymocyte apoptosis J:73738
lymph node hypoplasia J:73738
Il15ratm1.1Nsl/Il15ratm1.1Nsl
(B6.129X1-Il15ratm1.1Nsl)
abnormal T cell activation J:92705
abnormal T cell proliferation J:92705
increased interleukin-2 secretion J:92705
increased T cell proliferation J:92705
Il15ratm1.1Nsl/Il15ratm1.1Nsl
Tg(TcrAND)53Hed/?

(involves: 129X1/SvJ * C57BL/6 * SJL)
increased T cell proliferation J:92705
Il15ratm1Ama/Il15ratm1Ama
(involves: 129X1/SvJ)
abnormal NK cell physiology J:119213
decreased CD8-positive, alpha-beta T cell number J:142570
decreased CD8-positive, gamma-delta intraepithelial T cell number J:155298
decreased memory T cell number J:142570
decreased NK cell number J:119213, J:142570
decreased NK T cell number J:142570
decreased T cell proliferation J:142570
impaired natural killer cell mediated cytotoxicity J:142570
Il15ratm1Ama/Il15ratm2.1Ama
Lyz2tm1(cre)Ifo/0
Tg(Itgax-cre)1-1Reiz/0

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA)
abnormal immune system physiology J:155298
decreased CD8-positive, alpha-beta T cell number J:155298
decreased memory T cell number J:155298
decreased NK cell number J:155298
Il15ratm1Ama/Il15ratm2.1Ama
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J)
abnormal immune system physiology J:155298
abnormal NK cell differentiation J:155298
abnormal NK cell physiology J:155298
decreased CD8-positive, alpha-beta T cell number J:155298
decreased memory T cell number J:155298
decreased NK cell number J:155298
Il15ratm1Ama/Il15ratm2.1Ama
Tg(Itgax-cre)1-1Reiz/0

(involves: 129X1/SvJ * C57BL/6J * CBA)
abnormal NK cell differentiation J:155298
abnormal NK cell physiology J:155298
abnormal T cell subpopulation ratio J:155298
decreased CD8-positive, alpha-beta T cell number J:155298
decreased memory T cell number J:155298
decreased NK cell number J:155298
Il15ratm1Ama/Il15ratm2.1Ama
Tg(Vil1-cre)997Gum/0

(involves: C57BL/6J * SJL)
decreased CD8-positive, gamma-delta intraepithelial T cell number J:155298
Il15ratm1Wjl/Il15ratm1Wjl
(involves: 129 * C57BL/6)
abnormal T cell physiology J:142570
decreased CD8-positive, alpha-beta T cell number J:142570
decreased memory T cell number J:142570
decreased NK cell number J:142570
decreased NK T cell number J:142570
decreased T cell proliferation J:142570
Il16tm1Korn/Il16tm1Korn
(either: B6.129X1-Il16tm1Korn or C.129X1-Il16tm1Korn)
abnormal T cell physiology J:97739
Il17a/Il17ftm1.1Impr/Il17a/Il17ftm1.1Impr
(involves: C57BL/6)
abnormal effector T cell morphology J:187400
absent gamma-delta T cells J:187400
decreased interleukin-17 secretion J:187400
immune system phenotype J:187400, J:189794
increased gamma-delta T cell number J:187400
increased T cell proliferation J:187400
Il17a/Il17ftm1.1Impr/Il17a/Il17ftm1.1Impr
(involves: C57BL/6)
abnormal effector T cell morphology J:187400
absent gamma-delta T cells J:187400
decreased interleukin-17 secretion J:187400
immune system phenotype J:187400, J:189794
increased gamma-delta T cell number J:187400
increased T cell proliferation J:187400
Il17aem1(IMPC)Mbp/Il17aem1(IMPC)Mbp
(C57BL/6N-Il17aem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Il17atm1Cdon/Il17atm1Cdon
(involves: C57BL/6)
chronic inflammation J:136279
decreased CD4-positive, alpha-beta T cell number J:136279
decreased IgG1 level J:136279
decreased IgG2a level J:136279
decreased IgG2b level J:136279
decreased IgM level J:136279
decreased interleukin-17 secretion J:136279
decreased susceptibility to experimental autoimmune encephalomyelitis J:136279
increased susceptibility to induced colitis J:136279
Il17atm1Yiw/Il17atm1Yiw
(involves: 129P2/OlaHsd * C57BL/6J)
decreased IgG level J:79127
decreased immunoglobulin level J:79127
decreased interferon-gamma secretion J:79127
decreased susceptibility to type IV hypersensitivity reaction J:79127
Il17atm1Yiw/Il17atm1Yiw
(involves: 129P2/OlaHsd * BALB/cA * C57BL/6J)
abnormal interleukin level J:79127
abnormal Langerhans cell physiology J:79127
decreased IgE level J:79127
decreased IgG1 level J:79127
decreased immunoglobulin level J:79127
decreased susceptibility to type IV hypersensitivity reaction J:79127
Il17atm1Yiw/Il17atm1Yiw
(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to bacterial infection J:143719
Il17atm1Yiw/Il17atm1Yiw
(involves: 129P2/OlaHsd)
abnormal immune system physiology J:144710
decreased neutrophil cell number J:193548
increased gamma-delta T cell number J:193548
Il17atm1Yiw/Il17atm1Yiw
(B6.129P2-Il17atm1Yiw)
increased susceptibility to infection induced morbidity/mortality J:160680
Il17atm1Yiw/Il17atm1Yiw
Il1rntm1Yiw/Il1rntm1Yiw

(involves: 129P2/OlaHsd * BALB/cA * C57BL/6J)
decreased susceptibility to induced arthritis J:83408
Il17atm1Yiw/Il17atm1Yiw
Il17ftm1Yiw/Il17ftm1Yiw

(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to bacterial infection J:143719
Il17atm1Yiw/Il17atm1Yiw
Il17ftm1Yiw/Il17ftm1Yiw
Il1rntm1Yiw/Il1rntm1Yiw

(involves: 129 * BALB/c)
rheumatoid arthritis J:143719
Il17atm1Yiw/Il17atm1Yiw
Il17ftm2Yiw/Il17ftm2Yiw

(involves: 129P2/OlaHsd * BALB/c)
decreased IgG3 level J:143719
enlarged submandibular lymph nodes J:143719
increased IgG1 level J:143719
increased IgG2a level J:143719
increased IgG2b level J:143719
increased susceptibility to bacterial infection J:143719
nasal inflammation J:143719
Il17atm1Yiw/Il17atm1Yiw
Il17ftm2Yiw/Il17ftm2Yiw

(B6.129P2-Il17atm1Yiw Il17ftm2Yiw)
decreased IgG3 level J:143719
enlarged submandibular lymph nodes J:143719
increased IgG1 level J:143719
increased IgG2a level J:143719
increased IgG2b level J:143719
increased susceptibility to infection induced morbidity/mortality J:160680
Il17atm1Yiw/Il17atm1Yiw
Tg(CD2-Rorc)#Staka/0

(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to autoimmune disorder J:230700
Il17bem1Cya/Il17bem1Cya
(C57BL/6-Il17bem1Cya)
abnormal cytokine level J:339366
increased macrophage cytokine production J:339366
increased neutrophil cell number J:339366
increased susceptibility to induced colitis J:339366
Il17bGt(371C12)Cmhd/Il17bGt(371C12)Cmhd
(B6.129-Il17bGt(371C12)Cmhd)
abnormal chemokine secretion J:229778
abnormal interleukin secretion J:229778
decreased interleukin-4 secretion J:229778
increased eosinophil cell number J:229778
increased interleukin-1 beta secretion J:229778
increased interleukin-5 secretion J:229778
increased interleukin-6 secretion J:229778
increased interleukin-13 secretion J:229778
increased susceptibility to bacterial infection J:229778
increased susceptibility to induced colitis J:229778
increased T-helper 2 cell number J:229778
increased tumor necrosis factor secretion J:229778
Il17bGt(371C12)Cmhd/Il17bGt(371C12)Cmhd
Il25tm1.1Cdon/Il25tm1.1Cdon

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6)
immune system phenotype J:229778
Il17ctm1.1Cdon/Il17ctm1.1Cdon
(involves: 129S6/SvEvTac)
decreased CD4-positive, alpha-beta T cell number J:177650
decreased interferon-gamma secretion J:177650
decreased interleukin-17 secretion J:177650
decreased susceptibility to experimental autoimmune encephalomyelitis J:177650
Il17ctm1Lex/Il17ctm1Lex
(B6.129S5-Il17ctm1Lex)
immune system phenotype J:178967
Il17ftm1Awai/Il17f+
(involves: 129S6/SvEvTac * C57BL/6)
decreased interleukin-17 secretion J:144710
Il17ftm1Awai/Il17ftm1Awai
(involves: 129S6/SvEvTac * C57BL/6)
abnormal immune system physiology J:144710
decreased interleukin-17 secretion J:144710
Il17ftm1Cdon/Il17ftm1Cdon
(involves: C57BL/6)
chronic inflammation J:136279
decreased acute inflammation J:136279
decreased interleukin-17 secretion J:136279
decreased susceptibility to experimental autoimmune encephalomyelitis J:136279
decreased susceptibility to induced colitis J:136279
increased IgG2a level J:136279
Il17ftm1Yiw/Il17ftm1Yiw
(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to bacterial infection J:143719
Il17ftm1Yiw/Il17ftm1Yiw
Il1rntm1Yiw/Il1rntm1Yiw

(involves: 129 * BALB/c)
rheumatoid arthritis J:143719
Il17ratm1.2Kurs/Il17ratm1.2Kurs
(involves: 129S4/SvJae * BALB/cJ * C57BL/6 * SJL)
abnormal interleukin secretion J:196483
increased CD4-positive, alpha-beta T cell number J:196483
increased gamma-delta T cell number J:196483
increased interleukin-6 secretion J:196483
increased interleukin-17 secretion J:196483
increased T-helper 17 cell number J:196483
skin inflammation J:196483
Il17ratm1Koll/Il17ratm1Koll
(involves: 129 * C57BL/6)
abnormal granulocyte differentiation J:71097
abnormal interleukin-5 secretion J:139080
abnormal interleukin-13 secretion J:139080
decreased inflammatory response J:139080
decreased neutrophil cell number J:71097
impaired neutrophil recruitment J:71097
increased susceptibility to infection J:71097
Il17ratm1Koll/Il17ratm1Koll
(involves: 129)
abnormal T-helper 2 cell differentiation J:158594
decreased interleukin-9 secretion J:158594
decreased interleukin-17 secretion J:177650
impaired neutrophil recruitment J:136279
Il17rbtm1Anjm/Il17rbtm1Anjm
(BALB/c-Il17rbtm1Anjm)
decreased eosinophil cell number J:159464
decreased IgE level J:159464
increased susceptibility to parasitic infection J:159464
Il17rbtm1Anjm/Il17rbtm1Anjm
Il1rl1tm1Anjm/Il1rl1tm1Anjm

(involves: 129P2/OlaHsd * BALB/c)
decreased eosinophil cell number J:159464
decreased IgE level J:159464
increased susceptibility to parasitic infection J:159464
Il17rbtm1Bud/Il17rbtm1Bud
(B6.129-Il17rbtm1Bud)
decreased inflammatory response J:139080
decreased interleukin-5 secretion J:139080
decreased interleukin-13 secretion J:139080
Il17rbtm1Lex/Il17rbtm1Lex
(C.129-Il17rbtm1Lex)
abnormal chemokine secretion J:159874
abnormal osteoclast differentiation J:159874
decreased interleukin-5 secretion J:159874
decreased interleukin-6 secretion J:159874
Il17rbtm1Tgi/Il17rb+
(Not Specified)
decreased susceptibility to induced colitis J:229778
Il17rbtm1Tgi/Il17rbtm1Tgi
(B6.Cg-Il17rbtm1Tgi)
abnormal interleukin secretion J:184570
decreased interleukin-9 secretion J:184570
decreased interleukin-10 secretion J:184570
decreased interleukin-13 secretion J:184570
decreased interleukin-17 secretion J:184570
decreased NK T cell number J:184570
Il17rbtm1Tgi/Il17rbtm1Tgi
(C.Cg-Il17rbtm1Tgi)
abnormal interleukin secretion J:184570
decreased interleukin-5 secretion J:184570
decreased interleukin-9 secretion J:184570
decreased interleukin-10 secretion J:184570
decreased interleukin-13 secretion J:184570
decreased interleukin-17 secretion J:184570
Il17rbtm1Tgi/Il17rbtm1Tgi
(Not Specified)
decreased susceptibility to induced colitis J:229778
Il17rcem1(IMPC)Mbp/Il17rcem1(IMPC)Mbp
(C57BL/6NCrl-Il17rcem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Il17rctm1Lex/Il17rctm1Lex
(involves: C57BL/6)
abnormal chemokine level J:159874
decreased inflammatory response J:159874
decreased susceptibility to experimental autoimmune encephalomyelitis J:159874
increased interleukin-17 secretion J:159874
Il17retm1Lex/Il17retm1Lex
(B6.129S5-Il17retm1Lex)
increased susceptibility to induced colitis J:178967
Il17retm1Sdl/Il17retm1Sdl
(involves: C57BL/6)
increased susceptibility to bacterial infection J:178966
increased susceptibility to bacterial infection induced morbidity/mortality J:178966
Il18tm1Aki/Il18tm1Aki
(involves: 129P2/OlaHsd)
abnormal macrophage physiology J:112400
abnormal T-helper 1 physiology J:46514
decreased circulating interferon-gamma level J:46514
decreased circulating interleukin-18 level J:122588, J:46514
decreased interferon-gamma secretion J:46514
impaired natural killer cell mediated cytotoxicity J:46514
increased susceptibility to bacterial infection J:112400
Il18tm1Aki/Il18tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal microglial cell morphology J:122031
Il18tm1Aki/Il18tm1Aki
(C.129P2-Il18tm1Aki)
stomach inflammation J:120594
Il18tm1Aki/Il18tm1Aki
(B6.129P2-Il18tm1Aki)
impaired neutrophil chemotaxis J:125285
increased susceptibility to bacterial infection J:125285
increased susceptibility to induced colitis J:173245
Il18tm1Aki/Il18tm1Aki
Il1btm1Dch/Il1btm1Dch

(involves: 129P2/OlaHsd * 129S2/SvPas)
increased susceptibility to bacterial infection J:112400
Il18tm1Aki/Il18tm1Aki
Nlrp1aNeut1/Nlrp1aNeut1

(involves: 129P2/OlaHsd * C57BL/6)
abnormal inflammatory response J:191055
increased neutrophil cell number J:191055
myocarditis J:191055
Il18tm1Aki/Il18tm1Aki
Tg(KRT14-CASP1)1Miz/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased IgE level J:78602
decreased IgG1 level J:78602
immune system phenotype J:78602
Il18tm1Khe/Il18tm1Khe
(involves: 129P2/OlaHsd)
abnormal T cell morphology J:62263
decreased circulating interferon-gamma level J:62263
decreased circulating interleukin-18 level J:62263
decreased susceptibility to endotoxin shock J:62263
increased circulating tumor necrosis factor level J:62263
Il18tm1Khe/Il18tm1Khe
(B6.129P2-Il18tm1Khe)
abnormal cytokine level J:138759
decreased circulating interferon-gamma level J:138759
decreased circulating interleukin-6 level J:138759
decreased circulating interleukin-18 level J:138759
decreased interferon-gamma secretion J:138759
decreased susceptibility to bacterial infection J:138759
decreased tumor necrosis factor secretion J:138759
increased dendritic cell number J:138759
increased macrophage cell number J:138759
increased NK cell number J:138759
Il18tm1Liew/Il18tm1Liew
(involves: 129P2/OlaHsd * CD-1)
abnormal interferon level J:86621
abnormal interleukin level J:86621
abnormal tumor necrosis factor level J:86621
increased susceptibility to bacterial infection J:86621
increased susceptibility to parasitic infection J:86621
sepsis J:86621
Il18bptm1(KOMP)Vlcg/Il18bptm1(KOMP)Vlcg
(C57BL/6-Il18bptm1(KOMP)Vlcg)
abnormal NK cell differentiation J:255309
decreased interferon-gamma secretion J:255309
decreased KLRG1-positive NK cell number J:255309
decreased mature NK cell number J:255309
decreased NK cell number J:255309
increased circulating interferon-gamma level J:255309
increased immature NK cell number J:255309
Il18bptm1.1(KOMP)Vlcg/Il18bptm1.1(KOMP)Vlcg
(involves: C57BL/6N)
abnormal circulating chemokine level J:261967
abnormal lymph node morphology J:261967
abnormal macrophage activation involved in immune response J:261967
abnormal phagocyte morphology J:261967
abnormal spleen morphology J:261967
enlarged spleen J:261967
immune system phenotype J:261967
increased B cell number J:261967
increased circulating interferon-gamma level J:261967
increased circulating interleukin-18 level J:261967
increased macrophage cell number J:261967
increased monocyte cell number J:261967
Il18r1tm1Aki/Il18r1tm1Aki
(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal T-helper 1 physiology J:70298
decreased interferon-gamma secretion J:70298
impaired natural killer cell mediated cytotoxicity J:70298
Il18raptm1Yeh/Il18raptm1Yeh
(Not Specified)
abnormal cytokine secretion J:98417
abnormal leukocyte physiology J:98417
Il19tm2Vlcg/Il19tm2Vlcg
(B6.Cg-Il19tm2Vlcg)
decreased interleukin-6 secretion J:229575
decreased interleukin-10 secretion J:229575
decreased interleukin-13 secretion J:229575
immune system phenotype J:229575
increased interferon-gamma secretion J:229575
increased interleukin-1 beta secretion J:229575
increased interleukin-6 secretion J:229575
increased interleukin-12 secretion J:229575
increased susceptibility to colitis induced morbidity/mortality J:229575
increased susceptibility to induced colitis J:229575
increased tumor necrosis factor secretion J:229575
Il20tm1Lex/Il20tm1Lex
(B6;129S5-Il20tm1Lex/Mmucd)
abnormal type IV hypersensitivity reaction J:171883
Il20ratm1.1Misc/Il20ratm1.1Misc
(involves: C57BL/6)
abnormal osteoclast differentiation J:177783
Il20rbtm1Uwe/Il20rbtm1Uwe
(B6.129P2-Il20rbtm1Uwe)
abnormal cytotoxic T cell physiology J:143497
abnormal T-helper 1 physiology J:143497
decreased interleukin-4 secretion J:143497
decreased interleukin-10 secretion J:143497
increased interferon-gamma secretion J:143497
increased interleukin-2 secretion J:143497
increased memory T cell number J:143497
increased T cell proliferation J:143497
Il20rbtm1Uwe/Il20rbtm1Uwe
(C.129P2-Il20rbtm1Uwe)
increased susceptibility to type IV hypersensitivity reaction J:143497
Il21tm1Lex/Il21tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal gamma-delta T cell morphology J:123351
abnormal interleukin level J:123351
abnormal T cell differentiation J:123351
decreased CD4-positive, alpha-beta T cell number J:123351
decreased susceptibility to experimental autoimmune encephalomyelitis J:123351
increased susceptibility to experimental autoimmune encephalomyelitis J:137377
Il21tm1Lex/Il21tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:137867
abnormal CD4-positive, alpha-beta T cell physiology J:137867
abnormal germinal center B cell physiology J:137867
abnormal spleen germinal center morphology J:137867
decreased germinal center B cell number J:137867
decreased IgG1 level J:137867
decreased spleen germinal center number J:137867
Il21tm1Llit/Il21tm1Llit
(involves: 129 * C57BL/6J)
abnormal class switch recombination J:114783
increased IgE level J:114783
Il21rtm1Day/Il21rtm1Day
(involves: BALB/c * C57BL/6)
abnormal CD4-positive T cell differentiation J:136955, J:123352
abnormal dendritic cell physiology J:144708
abnormal Langerhans cell physiology J:144708
abnormal memory T cell physiology J:76043
abnormal NK cell physiology J:76043
abnormal plasmacytoid dendritic cell physiology J:144708
abnormal T cell activation J:76043
abnormal T cell physiology J:76043
abnormal thymocyte activation J:76043
decreased CD4-positive, alpha-beta T cell number J:123352
decreased cytotoxic T cell cytolysis J:76043
decreased IgE level J:144708
decreased IgG1 level J:76043, J:144708
decreased IgG2a level J:144708
decreased IgG2b level J:76043
decreased interferon-gamma secretion J:144708
decreased interleukin-4 secretion J:144708
decreased interleukin-13 secretion J:144708
decreased interleukin-17 secretion J:123352
decreased susceptibility to type IV hypersensitivity reaction J:144708
impaired natural killer cell mediated cytotoxicity J:76043
increased IgE level J:76043
increased interferon-gamma secretion J:76043, J:123352
Il21rtm1Day/Il21rtm1Day
(C57BL/6-Il21rtm1Day)
abnormal susceptibility to infection J:111712
abnormal T-helper 2 physiology J:111712
decreased IgG1 level J:111712
decreased IgG2b level J:111712
decreased interleukin-4 secretion J:111712
decreased interleukin-13 secretion J:111712
decreased interleukin-21 secretion J:111712
Il21rtm1Kopf/Il21rtm1Kopf
(involves: 129/Sv * BALB/c)
abnormal immunoglobulin level J:137508
abnormal lymphocyte physiology J:137508
decreased IgA level J:137508
decreased IgG1 level J:137508
immune system phenotype J:137377
impaired eosinophil recruitment J:137508
increased IgE level J:137508
Il21rtm1Kopf/Il21rtm1Kopf
(B6.129-Il21rtm1Kopf)
abnormal immune system morphology J:137508
abnormal immune system physiology J:137508
abnormal immunoglobulin level J:137508
abnormal leukocyte physiology J:137508
abnormal lymphocyte physiology J:137508
abnormal T-helper 1 physiology J:137508
abnormal T-helper 2 physiology J:137508
decreased basophil cell number J:137508
decreased eosinophil cell number J:137508
decreased granulocyte number J:137508
decreased IgA level J:137508
decreased IgG1 level J:137508
granulomatous inflammation J:137508
impaired eosinophil recruitment J:137508
increased IgE level J:137508
increased susceptibility to experimental autoimmune encephalomyelitis J:137377
Il21rtm1Wjl/Il21rtm1Wjl
(involves: 129 * C57BL/6)
abnormal CD8-positive, alpha-beta T cell physiology J:95221
abnormal immunoglobulin level J:80474
decreased cytotoxic T cell cytolysis J:95221
decreased IgG1 level J:80474
decreased IgG2a level J:80474
decreased IgG2b level J:80474
decreased IgG3 level J:80474
decreased interleukin-17 secretion J:124293
increased IgE level J:80474
Il21rtm1Wjl/Il21rtm1Wjl
(NOD.Cg-Il21rtm1Wjl)
abnormal CD4-positive T cell differentiation J:139075
decreased interleukin-17 secretion J:139075
decreased susceptibility to autoimmune diabetes J:139075
decreased T cell proliferation J:139075
Il21rtm1Wjl/Il21rtm1Wjl
Il4tm1Cgn/Il4tm1Cgn

(involves: 129 * C57BL/6)
abnormal immunoglobulin level J:80474
abnormal lymph node germinal center morphology J:80474
decreased IgA level J:80474
decreased IgG1 level J:80474
decreased IgG2a level J:80474
decreased IgG2b level J:80474
decreased IgG3 level J:80474
decreased IgM level J:80474
Il21rtm1Wjl/Il21rtm1Wjl
X/Yaa

(BXSB.129(Cg)-Il21rtm1Wjl/Dcr)
decreased susceptibility to systemic lupus erythematosus J:144484
Il22tm1.1(icre)Stck/Il22tm1.1(icre)Stck
(involves: 129X1/SvJ * C57BL/6N)
increased susceptibility to bacterial infection J:220074
Il22tm1.1Lex/Il22tm1.1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal cytokine secretion J:118261
ear inflammation J:118261
Il22tm1.1Lex/Il22tm1.1Lex
(involves: 129S5/SvEvBrd)
abnormal circulating cytokine level J:179011
colitis J:161073
decreased circulating interleukin-1 alpha level J:179011
decreased circulating interleukin-12 level J:179011
decreased circulating interleukin-12b level J:179011
decreased circulating tumor necrosis factor level J:179011
increased circulating interleukin-17 level J:179011
increased susceptibility to bacterial infection induced morbidity/mortality J:161073
increased susceptibility to fungal infection J:179011
lung inflammation J:179011
Il22tm1Flv/Il22+
(B6.Cg-Il22tm1Flv)
increased susceptibility to endotoxin shock J:126103
Il22tm1Flv/Il22tm1Flv
(B6.Cg-Il22tm1Flv)
increased susceptibility to endotoxin shock J:126103
liver inflammation J:126103
Il22tm1Flv/Il22tm1Flv
(involves: 129/Sv * C57BL/6)
increased susceptibility to induced colitis J:189217
Il22tm1Jcrd/Il22tm1Jcrd
(B6.Cg-Il22tm1Jcrd)
immune system phenotype J:155038
Il22tm1Jcrd/Il22tm1Jcrd
(Not Specified)
decreased neutrophil cell number J:193548
increased interleukin-17 secretion J:193548
Il22ra2tm2Vlcg/Il22ra2tm2Vlcg
(B6.Cg-Il22ra2tm2Vlcg)
colitis J:189217
Il23atm1.1Thak/Il23atm1.1Thak
(C57BL/6-Il23atm1.1Thak)
decreased interferon-gamma secretion J:143970
decreased interleukin-17 secretion J:143970
decreased susceptibility to experimental autoimmune encephalomyelitis J:143970
decreased T cell proliferation J:143970
Il23atm1Dnax/Il23atm1Dnax
(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:95542
decreased interleukin-17 secretion J:95542
decreased susceptibility to experimental autoimmune encephalomyelitis J:95542
Il23atm1Dnax/Il23atm1Dnax
(B6.Cg-Il23atm1Dnax)
abnormal CD8-positive, alpha-beta T cell physiology J:111568
abnormal granulocyte physiology J:111568
abnormal interleukin level J:111568
abnormal macrophage physiology J:111568
Il23atm1Dnax/Il23atm1Dnax
(Not Specified)
decreased gamma-delta T cell number J:193548
decreased interleukin-17 secretion J:193548
decreased leukocyte cell number J:193548
decreased neutrophil cell number J:193548
decreased T cell number J:193548
Il23atm1Gdy/Il23a+
(B6.Cg-Il23atm1Gdy)
increased susceptibility to induced colitis J:139557
Il23atm1Gdy/Il23atm1Gdy
(B6.Cg-Il23atm1Gdy)
increased susceptibility to induced colitis J:139557
Il23atm1Ngh/Il23atm1Ngh
(involves: 129S/SvEv * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:88235
abnormal CD8-positive, alpha beta T cell morphology J:88235
abnormal memory T cell physiology J:88235
decreased IgA level J:88235
decreased IgG2a level J:88235
decreased immunoglobulin level J:88235
Il23atm1Ngh/Il23atm1Ngh
(involves: 129 * C57BL/6)
abnormal circulating interleukin level J:216867
abnormal memory T cell physiology J:120806
decreased activated T cell number J:120806
decreased susceptibility to induced colitis J:216867
granulomatous inflammation J:120806
increased circulating interleukin-17 level J:216867
increased susceptibility to bacterial infection J:120806
Il23atm1Ngh/Il23atm1Ngh
(involves: 129)
increased susceptibility to bacterial infection induced morbidity/mortality J:161073
Il23rtm1.1Kuch/Il23rtm1.1Kuch
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:151907
decreased interleukin-9 secretion J:151907
Il23rtm1.1Ngh/Il23rtm1.1Ngh
(involves: C57BL/6)
abnormal circulating interleukin level J:216867
decreased susceptibility to induced colitis J:216867
increased circulating interleukin-17 level J:216867
Il23rtm1.1Ngh/Il23rtm1.1Ngh
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv * C57BL/6)
abnormal circulating interleukin level J:216867
decreased interleukin-17 secretion J:216867
Il23rtm1Dnax/Il23rtm1Dnax
(C57BL/6-Il23rtm1Dnax)
immune system phenotype J:111568
Il23rtm1Kuch/Il23rtm1Kuch
(C57BL/6-Il23rtm1Kuch)
abnormal CD4-positive T cell differentiation J:148248
abnormal CD4-positive, alpha-beta T cell physiology J:148248
decreased susceptibility to experimental autoimmune encephalomyelitis J:148248
Il25tm1.1Cdon/Il25tm1.1Cdon
(involves: 129S6/SvEvTac)
abnormal chemokine secretion J:229778
abnormal interleukin secretion J:229778
decreased eosinophil cell number J:229778
decreased interleukin-1 beta secretion J:229778
decreased interleukin-4 secretion J:229778, J:158594
decreased interleukin-5 secretion J:229778, J:158594
decreased interleukin-9 secretion J:158594
decreased interleukin-13 secretion J:229778, J:158594
decreased susceptibility to bacterial infection J:229778
decreased susceptibility to induced colitis J:229778
decreased T-helper 2 cell number J:229778
decreased tumor necrosis factor secretion J:229778
increased susceptibility to type I hypersensitivity reaction J:158594
lung inflammation J:158594
Il25tm1Anjm/Il25tm1Anjm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal interleukin secretion J:123748
abnormal mesenteric lymph node morphology J:123748
decreased eosinophil cell number J:123748
decreased interleukin-5 secretion J:123748
decreased interleukin-13 secretion J:123748
increased IgE level J:123748
increased susceptibility to parasitic infection J:123748
Il25tm1Cdon/Il25tm1Cdon
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N * SJL)
decreased susceptibility to induced colitis J:229778
Il25tm1Dart/Il25tm1Dart
(C57BL/6-Il25tm1Dart)
abnormal interferon level J:123808
abnormal interleukin level J:123808
abnormal response to infection J:123808
decreased IgG2a level J:123808
increased susceptibility to parasitic infection J:123808
intestinal inflammation J:123808
Il25tm1Dart/Il25tm1Dart
(involves: C57BL/6)
abnormal interleukin level J:125296
increased susceptibility to experimental autoimmune encephalomyelitis J:125296
increased T cell number J:125296
Il27tm1b(EUCOMM)Wtsi/Il27tm1b(EUCOMM)Wtsi
(C57BL/6N-Il27tm1b(EUCOMM)Wtsi/Wtsi)
decreased CD4-positive, alpha-beta memory T cell number J:211773
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
Il27tm1Cua/Il27tm1Cua
(C57BL/6-Il27tm1Cua)
abnormal CD4-positive T cell differentiation J:147706
increased susceptibility to experimental autoimmune encephalomyelitis J:147706
increased susceptibility to type IV hypersensitivity reaction J:147706
Il27tm1Lex/Il27tm1Lex
(involves: 129S/SvEvBrd)
increased circulating interleukin-12b level J:187660
increased interferon-gamma secretion J:187660
increased susceptibility to parasitic infection induced morbidity/mortality J:187660
Il27ratm1Fjs/Il27ratm1Fjs
(B6.Cg-Il27ratm1Fjs)
abnormal T-helper 1 physiology J:94856
decreased susceptibility to bacterial infection J:94856
increased lymphocyte cell number J:94856
Il27ratm1Mak/Il27ratm1Mak
(B6.129P2-Il27ratm1Mak)
abnormal T-helper 1 physiology J:116610, J:89509
decreased circulating interferon-gamma level J:116610
decreased interferon-gamma secretion J:116610, J:89509
decreased susceptibility to experimental autoimmune uveoretinitis J:116610
immune system phenotype J:88618
increased circulating interferon-gamma level J:88618
increased circulating interleukin-1 beta level J:88618
increased circulating interleukin-4 level J:88618
increased circulating interleukin-6 level J:88618
increased circulating interleukin-12 level J:88618
increased circulating tumor necrosis factor level J:88618
increased interferon-gamma secretion J:88618
increased interleukin-4 secretion J:88618
increased susceptibility to bacterial infection J:89509
increased susceptibility to parasitic infection J:89509
increased T cell proliferation J:89509
Il27ratm1Mak/Il27ratm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to induced arthritis J:151552
Il31ratm1Jagr/Il31ratm1Jagr
(involves: 129S5/SvEvBrd)
immune system phenotype J:91124
Il31ratm1Ngh/Il31ratm1Ngh
(C57BL/6-Il31ratm1Ngh)
spleen hypoplasia J:123111
Il31ratm1Ngh/Il31ratm1Ngh
(involves: C57BL/6)
abnormal interleukin level J:123198
abnormal macrophage physiology J:123198
granulomatous inflammation J:123198
increased IgE level J:123198
increased susceptibility to parasitic infection J:123198
increased T cell proliferation J:123198
Il33tm1(KOMP)Vlcg/Il33tm1(KOMP)Vlcg
(C57BL/6-Il33tm1(KOMP)Vlcg)
impaired macrophage chemotaxis J:232676
Il33tm1Aki/Il33tm1Aki
(involves: 129X1/SvJ * C57BL/6)
abnormal T-helper 2 physiology J:182160
decreased eosinophil cell number J:182160
decreased IgE level J:182160
immune system phenotype J:182160
increased susceptibility to parasitic infection J:182160
Il33tm1Amgn/Il33tm1Amgn
(B6.129-Il33tm1Amgn)
abnormal immune cell physiology J:192531
decreased lymphocyte cell number J:192531
increased susceptibility to parasitic infection J:192531
Il33tm1Snak/Il33tm1Snak
(involves: C57BL/6 * CBA)
decreased inflammatory response J:165513
decreased interleukin-1 alpha secretion J:165513
decreased interleukin-1 beta secretion J:165513
decreased interleukin-6 secretion J:165513
decreased susceptibility to endotoxin shock J:165513
immune system phenotype J:165513
increased susceptibility to induced colitis J:165513
lung inflammation J:165513
Il33tm2.1(IL33)Arte/Il33tm2.1(IL33)Arte
(involves: BALB/c * BALB/cJBomTac)
immune system phenotype J:227003
Il34tm1b(EUCOMM)Wtsi/Il34tm1b(EUCOMM)Wtsi
(involves: BALB/cJ * C57BL/6N)
abnormal microglial cell morphology J:187643
absent Langerhans cell J:187643
decreased dendritic cell number J:187643
decreased interferon-gamma secretion J:187643
decreased Langerhans cell number J:187643
decreased susceptibility to fungal infection J:187643
decreased susceptibility to type IV hypersensitivity reaction J:187643
immune system phenotype J:187643
increased susceptibility to Flaviviridae infection J:187643
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:187643
lymph node hypoplasia J:187643
Il36atm1Yiw/Il36atm1Yiw
(B6.129P2-Il36atm1Yiw)
abnormal cytokine level J:263315
immune system phenotype J:263315
Il36gtm1Lex/Il36gtm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal interleukin level J:264077
abnormal macrophage morphology J:264077
abnormal tumor necrosis factor level J:264077
decreased alveolar macrophage number J:264077
increased CD11b-high dendritic cell number J:264077
increased macrophage apoptosis J:264077
increased susceptibility to Orthomyxoviridae infection J:264077
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:264077
Il36gtm1Lex/Il36gtm1Lex
(involves: 129S5/SvEvBrd)
decreased CD4-positive, alpha-beta T cell number J:256437
decreased interleukin-9 secretion J:256437
decreased susceptibility to induced colitis J:256437
impaired neutrophil recruitment J:280917
increased CD4-positive, alpha-beta T cell number J:256437
increased regulatory T cell number J:256437
increased susceptibility to Herpesvirales infection J:280917
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:280917
Il36gtm1Lex/Il36gtm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal cytokine level J:296074
abnormal macrophage activation involved in immune response J:296074
impaired macrophage phagocytosis J:296074
increased susceptibility to bacterial infection J:296074
increased susceptibility to bacterial infection induced morbidity/mortality J:296074
Il36rntm1Hblu/Il36rn+
Tg(KRT14-Il1f6)1Hblu/?

(involves: 129 * C57BL/6 * DBA/2)
skin inflammation J:126327
Il36rntm1Hblu/Il36rntm1Hblu
(C.129(B6)-Il36rntm1Hblu)
increased susceptibility to chemically induced skin inflammation J:260118
Il36rntm1Hblu/Il36rntm1Hblu
Tg(KRT14-Il1f6)1Hblu/?

(involves: 129 * C57BL/6 * DBA/2)
skin inflammation J:126327
Il36rntm1Kopf/Il36rntm1Kopf
(B6.129S5-Il36rntm1Kopf)
dermatitis J:193548
increased leukocyte cell number J:193548
increased neutrophil cell number J:193548
Ilf2tm1Pnk/Ilf2+
(involves: C57BL/6)
immune system phenotype J:161086
Ilf3tm1.1Itl/Ilf3tm1.1Itl
(Not Specified)
increased susceptibility to Adenoviridae infection J:167126
Ilf3tm1Pnk/Ilf3+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:161086
Ilktm1Star/Ilktm1Star
Tg(KRT14-cre)1Amc/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
skin inflammation J:172934
Ilktm1Star/Ilktm1Star
Tg(NPHS2-cre)295Lbh/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
tubulointerstitial nephritis J:129286, J:129244
Ilktm1Star/Ilktm2Star
Tg(Acp5-cre)1Star/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal osteoclast physiology J:197593
increased osteoclast cell number J:197593
Im1Bioz:BP1/?
(involves: Bioz:BP1 * Bioz:MP1)
abnormal humoral immune response J:46394
Im2Bioz:BP1/?
(involves: Bioz:BP1 * Bioz:MP1)
abnormal humoral immune response J:37251
Im2Bioz:BP1/Im2Bioz:BP1
(involves: Bioz:BP1 * Bioz:MP1)
abnormal humoral immune response J:65671
Im3Bioz:BP1/?
(involves: Bioz:BP1 * Bioz:MP1)
abnormal humoral immune response J:46394
Im4Bioz:BP1/?
(involves: Bioz:BP1 * Bioz:MP1)
abnormal humoral immune response J:37251
Im5Bioz:BP1/?
(involves: Bioz:BP1 * Bioz:MP1)
abnormal humoral immune response J:37251
Im6Bioz:BP1/?
(involves: Bioz:BP1 * Bioz:MP1)
abnormal humoral immune response J:37251
Im7Bioz:BP1/?
(involves: Bioz:BP1 * Bioz:MP1)
abnormal humoral immune response J:37251
Imebt1DU6/?
(involves: DU6 * DUKs)
increased spleen weight J:99475
Imh1NZB/Imh1NZB
(involves: NZB * NZW)
increased IgM level J:26266
increased susceptibility to systemic lupus erythematosus J:26266
Imh1NZB/Imh1NZW
(involves: NZB * NZW)
increased IgM level J:26266
increased susceptibility to systemic lupus erythematosus J:22353
Imm1NZW/Imm1NZB
(involves: NZB * NZW)
abnormal immune system physiology J:26266
Imm1NZW/Imm1NZW
(involves: NZB * NZW)
abnormal immune system physiology J:26266
Immp2lTg(HLA-A/H2-D)2Enge/?
((C57BL/6 x CBA)F1)
abnormal cytotoxic T cell physiology J:31937
abnormal negative T cell selection J:31937
abnormal positive T cell selection J:31937
Impdh1tm1Bmi/Impdh1tm1Bmi
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immune system cell morphology J:85443
decreased T cell proliferation J:85443
Impdh1tm1Bmi/Impdh1tm1Bmi
Impdh2tm1Bmi/Impdh2+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal cytotoxic T cell physiology J:85443
abnormal immune system cell morphology J:85443
abnormal lymphopoiesis J:85443
decreased splenocyte proliferation J:85443
decreased T cell proliferation J:85443
Impdh2tm1Bmi/Impdh2+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal lymphocyte cell number J:86045
Impg1em1Visu/Impg1em1Visu
Impg2em1Visu/Impg2em1Visu

(involves: C57BL/6J * DBA/2)
microgliosis J:288311
Impg2em1Visu/Impg2em1Visu
(involves: C57BL/6J * DBA/2)
microgliosis J:288311
Imraq1DBA/2J/?
(involves: C57BL/6J * DBA/2J)
increased IgG level J:100370
Imraq2DBA/2J/?
Imraq3C57BL/6J/?

(involves: C57BL/6J * DBA/2J)
increased IgG level J:100370
Imrfq1C57BL/6J/?
Imrfq2C57BL/6J/?

(involves: C57BL/6J * DBA/2J)
increased IgG level J:100370
In(2a;Itch)18H/In(2a;Itch)18H
(involves: 101/H * C3H/HeH)
abnormal alveolar macrophage morphology J:24934
chronic inflammation J:24934
immune system phenotype J:205692
increased inflammatory response J:45910
increased spleen red pulp amount J:24934
interstitial pneumonia J:24934
lung inflammation J:24934
lymph node hyperplasia J:24934
Inavatm1.1Itl/Inavatm1.1Itl
(involves: 129S6/SvEvTac * C57BL/6NTac)
increased susceptibility to bacterial infection J:257317
increased susceptibility to induced colitis J:257317
Inca1tm1Cmt/Inca1tm1Cmt
(involves: 129 * C57BL/6N)
abnormal spleen B cell follicle morphology J:175667
abnormal spleen morphology J:175667
abnormal spleen white pulp morphology J:175667
increased IgA level J:175667
Ing1Gt(OST206270)Lex/Ing1Gt(OST206270)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
decreased thymocyte number J:118602
increased thymocyte apoptosis J:118602
Ing1tm1Avg/Ing1tm1Avg
(involves: 129S1/Sv * C57BL/6)
enlarged spleen J:105658
Ing2tm1.1Ccha/Ing2tm1.1Ccha
(involves: 129 * C57BL/6J * FVB/N)
spleen hyperplasia J:167311
Ing4em1(IMPC)Tcp/Ing4em1(IMPC)Tcp
(C57BL/6NCrl-Ing4em2(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Ing4Gt(XG370)Byg/Ing4Gt(XG370)Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal chemokine level J:161381
increased circulating interleukin-6 level J:161381
increased interleukin-6 secretion J:161381
Ing5tm1.1Ttho/Ing5tm1.1Ttho
(B6.Cg-Ing5tm1.1Ttho)
spleen hypoplasia J:345308
Inhatm1Bay/Inhatm1Bay
(involves: 129S7/SvEvBrd * C57BL/6)
chronic liver inflammation J:20450
Inhbbtm1Jae/Inhbbtm1Jae
(either: (129S4/SvJae-Inhbbtm1Jae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6))
increased incidence of corneal inflammation J:16995
Inmtem1(IMPC)Mbp/Inmtem1(IMPC)Mbp
(C57BL/6N-Inmtem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Inpp1tm1a(KOMP)Wtsi/Inpp1tm1a(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
decreased susceptibility to bacterial infection J:213427
Inpp4btm1.1Jva/Inpp4btm1.1Jva
(B6.129-Inpp4btm1.1Jva)
abnormal osteoclast differentiation J:177648
abnormal osteoclast morphology J:177648
increased osteoclast cell number J:177648
Inpp5del20/Inpp5del20
(B6.129-Inpp5del20)
abnormal lymphocyte cell number J:173266
decreased lymphocyte cell number J:173266
decreased pre-B cell number J:173266
decreased thymocyte number J:173266
enlarged spleen J:173266
increased circulating interleukin-6 level J:173266
increased IgG2a level J:173266
increased IgM level J:173266
increased immunoglobulin level J:173266
increased macrophage cell number J:173266
small thymus J:173266
Inpp5dm1Anu/Inpp5dm1Anu
(C57BL/6JAnu-Inpp5dm1Anu)
lung inflammation J:104190
Inpp5dm1Btlr/Inpp5dm1Btlr
(C57BL/6J-Inpp5dm1Btlr)
abnormal B cell differentiation J:140987
abnormal eosinophil physiology J:140987
abnormal neutrophil physiology J:140987
decreased cytotoxic T cell cytolysis J:140987
enlarged spleen J:140987
enlarged thymus J:140987
impaired natural killer cell mediated cytotoxicity J:140987
Inpp5dm2Btlr/Inpp5dm2Btlr
(C57BL/6J-Inpp5dm2Btlr)
decreased B cell number J:216053
Inpp5dM3Btlr/Inpp5d+
(C57BL/6J-Inpp5dM3Btlr)
decreased NK cell number J:254907
Inpp5dm4Btlr/Inpp5dm4Btlr
(C57BL/6J-Inpp5dm4Btlr)
increased interferon-beta secretion J:272854
increased tumor necrosis factor secretion J:272854
Inpp5dm5Btlr/Inpp5dm5Btlr
(C57BL/6J-Inpp5dm5Btlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:272856
abnormal lymphocyte morphology J:272856
abnormal T cell differentiation J:272856
decreased alpha-beta T cell number J:272856
decreased B cell number J:272856
decreased CD4-positive, alpha-beta T cell number J:272856
decreased CD8-positive, alpha-beta T cell number J:272856
decreased CD8-positive, naive alpha-beta T cell number J:272856
decreased NK cell number J:272856
increased B-1 B cell number J:272856
increased CD8-positive, alpha-beta T cell number J:272856
increased central memory CD8 positive, alpha-beta T cell number J:272856
increased effector memory CD4-positive, alpha-beta T cell number J:272856
increased effector memory CD8-positive, alpha-beta T cell number J:272856
Inpp5dtm1.1Wgk/Inpp5dtm1.1Wgk
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal leukocyte physiology J:94861
abnormal mononuclear cell differentiation J:94861
abnormal NK cell morphology J:95215
decreased susceptibility to graft versus host disease J:95215, J:94861
increased dendritic cell number J:94861
increased monocyte cell number J:94861
increased NK cell number J:95215
Inpp5dtm1Dmt/Inpp5dtm1Dmt
(involves: 129P2/OlaHsd)
abnormal leukocyte physiology J:77739
decreased B cell number J:77739
enlarged lymph nodes J:77739
enlarged spleen J:77739
increased leukocyte cell number J:77739
Inpp5dtm1Dmt/Inpp5dtm1Dmt
(B6.129P2/OlaHsd-Inpp5dtm1Dmt)
decreased lymphocyte cell number J:173266
decreased pre-B cell number J:173266
increased circulating interleukin-6 level J:173266
Inpp5dtm1Rav/Inpp5dtm1.1Rav
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen marginal zone macrophage morphology J:119256
absent marginal zone B cells J:119256
enlarged spleen J:119256
Inpp5dtm1Rav/Inpp5dtm1Rav
Cd79atm1(cre)Reth/Cd79a+
Tg(IghAb36-65)1Wys/0

(involves: 129 * BALB/c * C57BL/6 * FVB/N)
abnormal B cell anergy J:178833
abnormal B cell negative selection J:178833
decreased B cell number J:178833
increased autoantibody level J:178833
increased plasma cell number J:178833
Inpp5dtm1Rav/Inpp5dtm1Rav
Tg(Cd4-cre)1Cwi/?

(involves: C57BL/6 * DBA/2)
abnormal cytotoxic T cell physiology J:122796
abnormal humoral immune response J:122796
abnormal interferon level J:122796
abnormal interleukin secretion J:122796
abnormal lymph node germinal center morphology J:122796
decreased susceptibility to parasitic infection J:122796
Inpp5dtm1Rkh/Inpp5dtm1Rkh
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal granulocyte differentiation J:48193
abnormal lymphopoiesis J:48193
abnormal macrophage chemotaxis J:48193
abnormal monocyte differentiation J:48193
decreased lymphocyte cell number J:48193
increased monocyte cell number J:48193
increased neutrophil cell number J:48193
increased spleen weight J:48193
spleen hyperplasia J:48193
Inpp5dtm1Rkh/Inpp5dtm1Rkh
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal interleukin level J:173301
abnormal myelopoiesis J:117320
decreased pro-B cell number J:117320
ileum inflammation J:173301
increased circulating interleukin-6 level J:117320
intestinal inflammation J:173301
Inpp5dtm1Rkh/Inpp5dtm1Rkh
(involves: 129S1/Sv * 129X1/SvJ)
abnormal B cell physiology J:110864
abnormal CD4-positive, alpha-beta T cell physiology J:110864
abnormal CD8-positive, alpha-beta T cell physiology J:110864
abnormal cell-mediated immunity J:110864
abnormal macrophage chemotaxis J:110864
abnormal osteoclast differentiation J:78771
abnormal osteoclast morphology J:78771
abnormal osteoclast physiology J:78771
abnormal T cell physiology J:110864
increased circulating interleukin-6 level J:78771
increased mast cell degranulation J:120426
increased osteoclast cell number J:78771
Inpp5dtm1Rkh/Inpp5dtm1Rkh
Rag1tm1(GFP)Imku/Rag1+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal lymphopoiesis J:117320
Inpp5dtm1Wgk/Inpp5dtm1.1Wgk
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Inpp5dtm1Wgk/Inpp5dtm1.1Wgk Tg(Mx1-cre)1Cgn)
abnormal leukocyte physiology J:144110
abnormal myeloid leukocyte morphology J:144110
Inpp5dtm1Wgk/Inpp5dtm1Wgk
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Inpp5dtm1Wgk Tg(Mx1-cre)1Cgn)
decreased susceptibility to graft versus host disease J:144110
Inpp5jem1(IMPC)Mbp/Inpp5jem1(IMPC)Mbp
(C57BL/6NCrl-Inpp5jem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Inpp5kem1(IMPC)H/Inpp5k+
(C57BL/6NTac-Inpp5kem1(IMPC)H/H)
increased neutrophil cell number J:211773
Ins1tm1Jja/Ins1tm1Jja
(NOD.129S2-Ins1tm1Jja)
decreased susceptibility to autoimmune diabetes J:85309
Ins1tm1Jja/Ins1tm1Jja
Ins2tm1Jja/Ins2tm1Jja
Tg(Ins2*Y16A)1Ell/0

(NOD.Cg-Ins1tm1Jja Ins2tm1Jja Tg(Ins2*Y16A)1Ell)
decreased susceptibility to autoimmune diabetes J:98583
salivary gland inflammation J:98583
Ins1tm1Jja/Ins1tm1Jja
Ins2tm1Jja/Ins2tm1Jja
Tg(Ins2*Y16A)3Ell/0

(NOD.Cg-Ins1tm1Jja Ins2tm1Jja Tg(Ins2*Y16A)3Ell)
decreased anti-insulin autoantibody level J:98583
decreased susceptibility to autoimmune diabetes J:98583
salivary gland inflammation J:98583
Ins1tm1Jja/Ins1tm1Jja
Ins2tm1Mnt/Ins2tm1Mnt
Tg(Aire-cre)1Mnt/0

(involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * FVB/N)
abnormal immune system physiology J:152798
abnormal interferon-gamma secretion J:152798
abnormal T cell physiology J:152798
increased anti-insulin autoantibody level J:152798
pancreas inflammation J:152798
Ins1tm1Jja/Ins1tm1Jja
Tg(Ins2*Y16A)1Ell/0

(NOD.Cg-Ins1tm1Jja Tg(Ins2*Y16A)1Ell)
increased susceptibility to autoimmune diabetes J:98583
Ins1tm1Jja/Ins1tm1Jja
Tg(Ins2*Y16A)3Ell/0

(NOD.Cg-Ins1tm1Jja Tg(Ins2*Y16A)3Ell)
autoimmune response J:98583
Ins2Akita/Ins2+
(C57BL/6-Ins2Akita/J)
abnormal microglial cell morphology J:99412
abnormal response to transplant J:76224
increased leukocyte cell number J:99412
Ins2Akita/Ins2+
Prf1tm1Sdz/Prf1tm1Sdz
Rag1tm1Mom/Rag1tm1Mom

(NOD.Cg-Rag1tm1Mom Ins2Akita Prf1tm1Sdz)
absent mature B cells J:138005
absent T cells J:138005
increased granulocyte number J:138005
increased macrophage cell number J:138005
increased monocyte cell number J:138005
Ins2C95S/Ins2+
(C3HeB/FeJ-Ins2C95S)
increased susceptibility to autoimmune diabetes J:122098
Ins2C95S/Ins2C95S
(C3HeB/FeJ-Ins2C95S)
increased susceptibility to autoimmune diabetes J:122098
Ins2tm1Jja/Ins2tm1Jja
(NOD.129S2-Ins2tm1Jja)
increased anti-insulin autoantibody level J:85309
insulitis J:85309
Ins2tm1Jja/Ins2tm1Jja
Tg(Ins2*Y16A)3Ell/0

(NOD.Cg-Ins2tm1Jja Tg(Ins2*Y16A)3Ell)
autoimmune response J:98583
increased anti-insulin autoantibody level J:98583
Insrm1Btlr/Insrm1Btlr
(C57BL/6J-Insrm1Btlr)
increased susceptibility to induced colitis J:267534
Insrtm1Khn/Insrtm1Khn
Leprtm1.1Chua/Leprtm1.1Chua
Tg(Pomc1-cre)16Lowl/0

(involves: 129 * 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * FVB/N)
liver inflammation J:192274
ovary inflammation J:192274
white adipose tissue inflammation J:192274
Insyn2bem1(IMPC)J/Insyn2bem1(IMPC)J
(C57BL/6NJ-Insyn2bem1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Invsinv/Invsinv
(FVB/N-Invsinv)
abnormal spleen morphology J:48533
spleen hypoplasia J:48533
Ip6k2tm1.1Snyd/Ip6k2tm1.1Snyd
(B6.129-Ip6k2tm1.1Snyd)
abnormal B cell physiology J:212482
Ipo7em1(IMPC)Mbp/Ipo7+
(C57BL/6N-Ipo7em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Ipptm1.1(KOMP)Vlcg/Ipptm1.1(KOMP)Vlcg
(C57BL/6N-Ipptm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Iqcetm1b(EUCOMM)Hmgu/Iqcetm1b(EUCOMM)Hmgu
(C57BL/6N-Iqcetm1b(EUCOMM)Hmgu/Ics)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Iqgap1tm1b(EUCOMM)Wtsi/Iqgap1tm1b(EUCOMM)Wtsi
(C57BL/6N-Iqgap1tm1b(EUCOMM)Wtsi/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Irag1em1(IMPC)Ccpcz/Irag1em1(IMPC)Ccpcz
(C57BL/6NCrl-Irag1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased effector memory T-helper cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Irak1tm1.1Pcoh/?
(involves: 129P2/OlaHsd)
decreased interferon-alpha secretion J:205798
immune system phenotype J:205798
Irak1tm1.1Pcoh/?
Irak2tm1.1Pcoh/?

(involves: 129P2/OlaHsd * C57BL/6)
decreased interferon-alpha secretion J:205798
Irak1tm1Jth/Y
(B6.Cg-Irak1tm1Jth)
decreased susceptibility to experimental autoimmune encephalomyelitis J:82302
Irak1tm1Jth/Y
Irak2tm1Aki/Irak2tm1Aki

(involves: 129/Sv * C57BL/6)
abnormal dendritic cell physiology J:136290
abnormal macrophage physiology J:136290
decreased susceptibility to endotoxin shock J:136290
Irak1tm1Jth/Y
Tg(Myh6-Tnf)1Brgi/?

(involves: 129/Sv * C57BL/6J * SJL)
myocarditis J:84829
Irak1tm1Jth/Irak1tm1Jth
(B6.Cg-Irak1tm1Jth)
decreased susceptibility to experimental autoimmune encephalomyelitis J:82302
Irak1tm1Jth/Irak1tm1Jth
Tg(Myh6-Tnf)1Brgi/?

(involves: 129/Sv * C57BL/6J * SJL)
myocarditis J:84829
Irak2tm1.1Pcoh/?
(involves: C57BL/6)
decreased interferon-alpha secretion J:205798
Irak2tm1Aki/Irak2tm1Aki
(involves: 129/Sv * C57BL/6)
abnormal macrophage physiology J:136290
decreased susceptibility to endotoxin shock J:136290
Irak2tm1Jth/Irak2tm1Jth
(involves: 129 * C57BL/6)
abnormal chemokine level J:149258
decreased circulating interleukin-6 level J:149258
decreased circulating tumor necrosis factor level J:149258
decreased interleukin-6 secretion J:149258
decreased susceptibility to endotoxin shock J:149258
decreased tumor necrosis factor secretion J:149258
Irak3tm1Flv/Irak3tm1Flv
(involves: 129S1/Sv * C57BL/6)
abnormal immune system morphology J:78189
abnormal inflammatory response J:78189
abnormal innate immunity J:78189
abnormal osteoclast physiology J:98035
abnormal Peyer's patch morphology J:78189
enlarged Peyer's patches J:78189
increased interleukin-6 secretion J:78189
increased interleukin-12b secretion J:78189
increased neutrophil cell number J:78189
increased osteoclast cell number J:98035
increased susceptibility to endotoxin shock J:78189
increased tumor necrosis factor secretion J:78189
Irak3tm1Flv/Irak3tm1Flv
(NOD.129S1(B6)-Irak3tm1Flv)
abnormal dendritic cell physiology J:229884
abnormal professional antigen presenting cell physiology J:229884
abnormal T cell activation J:229884
abnormal T cell differentiation J:229884
increased anti-insulin autoantibody level J:229884
increased effector memory T-helper cell number J:229884
increased susceptibility to autoimmune diabetes J:229884
insulitis J:229884
Irak4m1Btlr/Irak4m1Btlr
(C57BL/6J-Irak4m1Btlr)
decreased tumor necrosis factor secretion J:133271
Irak4m1Btlr/Irak4m1Btlr
Ptpn6m1Btlr/Ptpn6m1Btlr

(C57BL/6J-Ptpn6m1Btlr Irak4m1Btlr)
immune system phenotype J:142845
Irak4m1Btlr/Irak4m1Btlr
Ticam1Lps2/Ticam1Lps2

(involves: C57BL/6J)
decreased tumor necrosis factor secretion J:187583
Irak4tm1Aki/Irak4tm1Aki
(involves: 129X1/SvJ * C57BL/6)
abnormal cytokine secretion J:125729
decreased B cell proliferation J:125729
decreased interferon-alpha secretion J:125729
decreased interleukin-6 secretion J:125729
decreased interleukin-12b secretion J:125729
decreased susceptibility to endotoxin shock J:125729
decreased tumor necrosis factor secretion J:125729
immune system phenotype J:125729
Irak4tm1Gram/Irak4tm1Gram
(involves: BALB/c)
abnormal chemokine secretion J:121912
abnormal cytokine secretion J:121912
Irak4tm1Lix/Irak4tm1Lix
(involves: C57BL/6)
abnormal chemokine secretion J:125732
decreased acute inflammation J:125732
decreased circulating interleukin-6 level J:125732
decreased circulating tumor necrosis factor level J:125732
decreased interferon-alpha secretion J:125732
decreased interferon-beta secretion J:125732
decreased interleukin-6 secretion J:125732
decreased susceptibility to endotoxin shock J:125732
decreased tumor necrosis factor secretion J:125732
Irak4tm1Yeh/Irak4tm1Yeh
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal cytokine level J:76098
abnormal cytokine secretion J:76098
abnormal macrophage physiology J:76098
abnormal NK cell physiology J:76098
decreased B cell proliferation J:76098
decreased circulating interferon-gamma level J:76098
decreased circulating interleukin-1 level J:76098
decreased circulating interleukin-6 level J:76098
decreased circulating tumor necrosis factor level J:76098
decreased interleukin-6 secretion J:76098
decreased susceptibility to endotoxin shock J:76098
decreased tumor necrosis factor secretion J:76098
increased susceptibility to bacterial infection J:76098
Irak4tm2Aki/Irak4tm2Aki
(involves: 129X1/SvJ * C57BL/6)
abnormal cytokine secretion J:125729
decreased B cell proliferation J:125729
decreased interferon-alpha secretion J:125729
decreased interleukin-6 secretion J:125729
decreased interleukin-12b secretion J:125729
decreased susceptibility to endotoxin shock J:125729
decreased tumor necrosis factor secretion J:125729
immune system phenotype J:125729
Irav1C57BL/J/Irav1DBA/2J
(involves: C57BL/6J * DBA/2J)
abnormal cell-mediated immunity J:122129
abnormal cytokine secretion J:122129
Irav1DBA/2J/Irav1DBA/2J
(involves: C57BL/6J * DBA/2J)
abnormal cell-mediated immunity J:122129
abnormal cytokine secretion J:122129
Ireb2tm1.2Mwh/Ireb2tm1.2Mwh
(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL)
decreased spleen iron level J:103414
Ireb2tm1Mwh/Ireb2tm1Mwh
(involves: 129P2/OlaHsd * C57BL/6J)
decreased spleen iron level J:105124
Ireb2tm1Roua/Ireb2tm1Roua
(B6.Cg-Ireb2tm1Roua)
decreased spleen iron level J:176655
Irf1M1Btlr/Irf1+
(C57BL/6J-Irf1M1Btlr)
decreased CD8-positive, alpha-beta T cell number J:162995
decreased NK cell number J:162995
immune system phenotype J:162995
impaired natural killer cell mediated cytotoxicity J:162995
increased susceptibility to Herpesvirales infection J:162995
Irf1M1Btlr/Irf1M1Btlr
(C57BL/6J-Irf1M1Btlr)
decreased CD8-positive, alpha-beta T cell number J:162995
decreased interferon-alpha secretion J:162995
decreased interferon-beta secretion J:162995
decreased NK cell number J:162995
immune system phenotype J:162995
impaired natural killer cell mediated cytotoxicity J:162995
increased susceptibility to Herpesvirales infection J:162995
Irf1m2Btlr/Irf1m2Btlr
(C57BL/6J-Irf1m2Btlr)
decreased CD8-positive, alpha-beta T cell number J:267675
decreased NK cell number J:267675
increased B-1 B cell number J:267675
increased CD4-positive, alpha-beta T cell number J:267675
Irf1M3Btlr/Irf1M3Btlr
(C57BL/6J-Irf1M3Btlr)
decreased CD8-positive, alpha-beta T cell number J:267677
increased CD4-positive, alpha-beta T cell number J:267677
Irf1tm1Cwe/Irf1tm1Cwe
(involves: 129/Sv * C57BL/6)
abnormal cytokine level J:110672
abnormal immune system morphology J:21235
abnormal immune system physiology J:43086
abnormal immunoglobulin level J:101427
abnormal macrophage physiology J:43086
abnormal splenocyte morphology J:21235
abnormal T cell morphology J:21235, J:36025
abnormal thymus cell ratio J:36025
decreased CD8-positive, alpha-beta T cell number J:21235
decreased circulating interleukin-2 level J:110672
decreased susceptibility to induced arthritis J:43086
increased circulating interferon-gamma level J:110672
increased circulating interleukin-3 level J:110672
increased circulating interleukin-4 level J:110672
increased circulating interleukin-5 level J:110672
increased circulating interleukin-6 level J:110672
increased susceptibility to Poxviridae infection J:101427
increased T-helper 2 cell number J:110672
Irf1tm1Cwe/Irf1tm1Cwe
(involves: 129)
abnormal circulating interleukin-4 level J:84367
abnormal circulating interleukin-10 level J:84367
abnormal cytokine level J:84367
abnormal T cell proliferation J:84367
decreased circulating interferon-gamma level J:84367
decreased susceptibility to experimental autoimmune encephalomyelitis J:84367
increased circulating interleukin-5 level J:84367
increased circulating interleukin-6 level J:84367
increased circulating interleukin-13 level J:84367
Irf1tm1Mak/Irf1tm1Mak
(either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * C57BL/6J * DBA/2))
abnormal response to infection J:64286
abnormal T cell number J:64286
decreased CD8-positive, alpha-beta T cell number J:64286
immune system phenotype J:64286
increased CD4-positive, alpha-beta T cell number J:64286
increased double-positive T cell number J:64286
Irf1tm1Mak/Irf1tm1Mak
(B6.129S2-Irf1tm1Mak/J)
abnormal lymphocyte physiology J:91927
decreased interferon-gamma secretion J:91927
Irf2tm1Mak/Irf2tm1Mak
(either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * C57BL/6J * DBA/2))
abnormal immune system physiology J:64286
abnormal response to infection J:64286
decreased B cell proliferation J:64286
decreased IgG2a level J:64286
decreased mature B cell number J:64286
decreased T cell number J:64286
immune system phenotype J:64286
Irf2tm1Mak/Irf2tm1Mak
(involves: 129S2/SvPas * C57BL/6)
dermatitis J:66034
enlarged inguinal lymph nodes J:66034
increased memory T cell number J:66034
lymph node hyperplasia J:66034
Irf3em1(IMPC)Mbp/Irf3em1(IMPC)Mbp
(C57BL/6N-Irf3em1(IMPC)Mbp/MbpMmucd)
enlarged lymph nodes J:211773
Irf3tm1Ttg/Irf3tm1Ttg
(involves: 129S/SvEv * C57BL/6J)
abnormal circulating interferon level J:98127
increased susceptibility to Picornaviridae infection J:98127
Irf3tm1Ttg/Irf3tm1Ttg
Irf7tm1Ttg/Irf7tm1Ttg

(involves: 129P2/OlaHsd * 129S/SvEv)
decreased interferon-beta secretion J:158969
decreased interleukin-1 beta secretion J:158969
increased susceptibility to bacterial infection J:158969
increased susceptibility to Herpesvirales infection J:158969
increased susceptibility to Paramyxoviridae infection J:158969
Irf3tm1Ttg/Irf3tm1Ttg
Irf9tm1Ttg/Irf9tm1Ttg

(involves: 129S/SvEv * C57BL/6J)
abnormal cytokine secretion J:98127
Irf3tm1Ttg/Irf3tm1Ttg
Sting1em1Jmin/Sting1em1Jmin

(involves: 129S/SvEv * C57BL/6N)
decreased single-positive T cell number J:251372
lung inflammation J:251372
Irf4em1(IMPC)Mbp/Irf4em1(IMPC)Mbp
(C57BL/6N-Irf4em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Irf4m1Btlr/Irf4m1Btlr
(C57BL/6J-Irf4m1Btlr)
abnormal B cell activation J:160882
decreased IgG level J:160882
decreased IgM level J:160882
Irf4m1Btlr/Irf4m1Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
decreased IgG level J:185495
decreased IgM level J:185495
immune system phenotype J:185495
Irf4M2Btlr/Irf4+
(C57BL/6J-Irf4M2Btlr)
abnormal B cell activation J:234245
decreased IgG level J:234245
decreased IgM level J:234245
Irf4M2Btlr/Irf4M2Btlr
(C57BL/6J-Irf4M2Btlr)
abnormal B cell activation J:234245
decreased IgG level J:234245
decreased IgM level J:234245
Irf4tm1.1Rdf/Irf4tm1.1Rdf
(involves: 129S1/Sv * 129S4/SvJae * C57BL/6)
abnormal B cell differentiation J:112643
abnormal B cell physiology J:112643
absent spleen germinal center J:112643
decreased B cell proliferation J:112643
decreased IgG1 level J:112643
Irf4tm1Mak/Irf4tm1Mak
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:42683
abnormal immune system cell morphology J:42683
abnormal immune system physiology J:42683
abnormal lymph node morphology J:42683
abnormal spleen morphology J:42683
absent lymph node germinal center J:42683
absent plasma cells J:42683
absent spleen germinal center J:42683
arrested B cell differentiation J:42683
decreased B cell proliferation J:42683
decreased dendritic cell number J:91043
decreased immunoglobulin level J:42683
decreased T cell proliferation J:42683
enlarged lymph nodes J:42683
enlarged spleen J:42683
immune system phenotype J:169863
increased lymphocyte cell number J:42683
increased susceptibility to Riboviria infection J:42683
Irf4tm1Mak/Irf4tm1Mak
(B6.129P2-Irf4tm1Mak)
abnormal CD4-positive, alpha beta T cell morphology J:78909
abnormal T-helper 1 cell differentiation J:78909
increased susceptibility to bacterial infection J:78909
Irf4tm1Mak/Irf4tm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
decreased plasmacytoid dendritic cell number J:97716
increased susceptibility to bacterial infection J:81744
Irf4tm1Rdf/Irf4tm1.1Rdf
(involves: 129S1/Sv * 129S4/SvJae * C57BL/6)
immune system phenotype J:112643
Irf4tm1Rdf/Irf4tm1.1Rdf
(involves: 129S1/Sv * 129S4/SvJae * C57BL/6)
abnormal B cell physiology J:112643
Irf5tm1e(EUCOMM)Wtsi/Irf5tm1e(EUCOMM)Wtsi
(C57BL/6N-Irf5tm1e(EUCOMM)Wtsi/Wtsi)
decreased CD4-positive, alpha-beta memory T cell number J:211773
decreased leukocyte cell number J:211773
Irf5tm1Ttg/Irf5tm1Ttg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T-helper 1 physiology J:97567
decreased circulating interleukin-6 level J:97567
decreased circulating interleukin-12b level J:97567
decreased circulating tumor necrosis factor level J:97567
decreased susceptibility to bacterial infection J:97567
immune system phenotype J:182658
Irf5tm1Ttg/Irf5tm1Ttg
(B6.129P2-Irf5tm1Ttg)
abnormal response to infection J:182658
decreased interferon-alpha secretion J:182658
decreased interleukin-6 secretion J:182658
decreased tumor necrosis factor secretion J:182658
immune system phenotype J:182658
Irf7m1Btlr/Irf7+
(C57BL/6J-Irf7m1Btlr)
decreased interferon-alpha secretion J:159358
decreased interferon-beta secretion J:159358
Irf7m1Btlr/Irf7m1Btlr
(C57BL/6J-Irf7m1Btlr)
decreased interferon-alpha secretion J:159358
decreased interferon-beta secretion J:159358
Irf7M2Btlr/Irf7+
(C57BL/6J-Irf7M2Btlr)
decreased circulating interferon-beta level J:217798
Irf7M2Btlr/Irf7M2Btlr
(C57BL/6J-Irf7M2Btlr)
decreased circulating interferon-beta level J:217798
Irf7tm1Ttg/Irf7tm1Ttg
(involves: 129P2/OlaHsd)
abnormal interferon level J:97662
abnormal T cell physiology J:97662
increased susceptibility to Herpesvirales infection J:97662
increased susceptibility to Picornaviridae infection J:97662
Irf7tm1Ttg/Irf7tm1Ttg
(B6.129P2-Irf7tm1Ttg)
increased susceptibility to Orthomyxoviridae infection J:233979
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:233979
Irf8em1Kmm/Irf8em1Kmm
Rr253em6Kmm/Rr253em6Kmm

(C57BL/6J-Irf8em1Kmm Rr253em6Kmm)
decreased dendritic cell number J:334296
decreased monocyte cell number J:334296
immune system phenotype J:334296
increased dendritic cell number J:334296
Irf8M1Btlr/Irf8M1Btlr
(C57BL/6J-Irf8M1Btlr)
abnormal interferon secretion J:166600
decreased macrophage cell number J:166600
decreased monocyte cell number J:166600
increased neutrophil cell number J:166600
Irf8m2Btlr/Irf8m2Btlr
(C57BL/6J-Irf8m2Btlr)
decreased CD8-positive, alpha-beta T cell number J:274937
increased CD4-positive, alpha-beta T cell number J:274937
Irf8myls/Irf8+
(involves: BXH2/TyJ * C57BL/6)
increased B cell number J:168923
increased B-1b cell number J:168923
increased follicular B cell number J:168923
increased transitional stage B cell number J:168923
Irf8myls/Irf8myls
(involves: BALB/cJ * BXH2/TyJ-Irf8myls)
abnormal myelopoiesis J:97931
enlarged spleen J:97931
Irf8myls/Irf8myls
Slc11a1r/Slc11a1r

(BXH2/TyJ)
abnormal myelopoiesis J:97931
decreased interferon-gamma secretion J:97931
decreased interleukin-12 secretion J:97931
enlarged spleen J:97931
increased susceptibility to bacterial infection J:97931
Irf8myls/Irf8myls
Slc11a1r/Slc11a1r

(involves: BXH2/TyJ * C57BL/6J)
increased susceptibility to bacterial infection J:97931
Irf8myls/Irf8myls
Slc11a1r/Slc11a1r

(involves: BALB/cJ * BXH2/TyJ)
increased susceptibility to bacterial infection J:97931
Irf8myls/Irf8myls
Slc11a1r/Slc11a1r

(involves: BXH2/TyJ * C3H/HeJ)
enlarged spleen J:97931
increased susceptibility to bacterial infection J:97931
Irf8myls/Irf8myls
Slc11a1r/Slc11a1s

(involves: BXH2/TyJ * C57BL/6J)
increased susceptibility to bacterial infection J:97931
Irf8myls/Irf8myls
Slc11a1r/Slc11a1s

(involves: BALB/cJ * BXH2/TyJ)
increased susceptibility to bacterial infection J:97931
Irf8myls/Irf8myls
Slc11a1s/Slc11a1s

(involves: BALB/cJ * BXH2/TyJ)
increased susceptibility to bacterial infection J:97931
Irf8tm1Hor/Irf8tm1Hor
(either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal cytotoxic T cell physiology J:36038
abnormal plasma cell number J:36038
decreased B cell number J:36038
decreased interferon-gamma secretion J:36038
decreased lymphocyte cell number J:36038
decreased T cell number J:36038
enlarged lymph nodes J:36038
hepatosplenomegaly J:36038
increased B cell number J:36038
increased granulocyte number J:36038
increased immunoglobulin level J:36038
increased leukocyte cell number J:36038
increased lymphocyte cell number J:36038
increased macrophage cell number J:36038
increased mature B cell number J:36038
increased spleen red pulp amount J:36038
increased spleen weight J:36038
increased susceptibility to Riboviria infection J:36038
spleen hyperplasia J:36038
Irf8tm1Hor/Irf8tm1Hor
(B6.129P2-Irf8tm1Hor)
decreased follicular B cell number J:168923
increased B-1b cell number J:168923
increased marginal zone B cell number J:168923
Irf8tm1Hor/Irf8tm1Hor
(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:181366
Irf8tm1Hor/Irf8tm1Hor
Irf4tm1Mak/Irf4tm1Mak

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:84577
abnormal pre-B cell morphology J:84577
absent B cells J:84577
arrested B cell differentiation J:84577
decreased dendritic cell number J:97716
decreased IgM level J:84577
decreased lymphocyte cell number J:84577
decreased plasmacytoid dendritic cell number J:97716
decreased T cell number J:84577
increased pre-B cell number J:84577
Irf9M1Btlr/Irf9+
(C57BL/6J-Irf9M1Btlr)
increased circulating interferon-beta level J:236674
Irf9M1Btlr/Irf9M1Btlr
(C57BL/6J-Irf9M1Btlr)
increased circulating interferon-beta level J:236674
Irf9tm1Ttg/Irf9tm1Ttg
(B6.Cg-Irf9tm1Ttg)
decreased interferon-alpha secretion J:97662
Irf9tm1Ttg/Irf9tm1Ttg
(either: (involves: C57BL/6 * CBA * ICR) or (involves: A/J * C57BL/6 * CBA))
increased susceptibility to viral infection J:77456
Irgcem1(IMPC)Tcp/Irgcem1(IMPC)Tcp
(C57BL/6N-Irgcem1(IMPC)Tcp/Tcp)
increased monocyte cell number J:211773
Irgm1tm1Gat/Irgm1tm1Gat
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:87535
increased circulating interferon-gamma level J:87535
increased circulating interleukin-12 level J:87535
increased susceptibility to bacterial infection J:87535
increased susceptibility to parasitic infection J:87535
Irgm2em1Myam/Irgm2em1Myam
(C57BL/6-Irgm2em1Myam)
increased susceptibility to parasitic infection J:308470
increased susceptibility to parasitic infection induced morbidity/mortality J:308470
Irs1Sml/Irs1Sml
(C3.Cg-Irs1Sml H2b/GrsrJ)
increased osteoclast cell number J:163661
Irs1tm1Mfw/Irs1tm1Mfw
Irs2tm2Mfw/Irs2tm2Mfw
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA)
increased susceptibility to autoimmune diabetes J:137845
Irs1tm1Tka/Irs1tm1Tka
(involves: C57BL/6 * CBA)
abnormal osteoclast differentiation J:61479
abnormal osteoclast physiology J:61479
Irs1tm2Tka/Irs1tm2Tka
Irs2tm2Tka/Irs2tm2Tka
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA)
increased susceptibility to autoimmune diabetes J:137846
Is(14)1Rdf Is(14)2Rdf/Del(14Trim13-Dleu2)4Rdf
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
increased B cell number J:156946
increased B-1a cell number J:156946
increased spleen white pulp amount J:156946
Is(14)1Rdf Is(14)5Rdf/Del(14Trim13-Rnaseh2b)6Rdf
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
abnormal lymphopoiesis J:179879
increased B cell number J:179879
Is(14)1Rdf/Is(14)1Rdf
Is(14)5Rdf/Is(14)5Rdf
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
abnormal lymphopoiesis J:179879
increased B cell number J:179879
Isg15tm1Kpk/Isg15tm1Kpk
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:100028
Isl1Drsh/Isl1+
(C3HeB/FeJ-Isl1Drsh)
increased susceptibility to otitis media J:202214
Isl1tm1(cre)Sev/Isl1+
Pax9tm1Rbal/Pax9tm1.1Hpt

(involves: 129 * C57BL/6J)
ectopic thymus J:311535
thymus hypoplasia J:311535
Isy1em1(IMPC)J/Isy1+
(C57BL/6NJ-Isy1em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Itchtm1.1Alta/Itchtm1.1Alta
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immunoglobulin level J:204685
abnormal interleukin secretion J:204685
abnormal lymph organ size J:204685
abnormal lymphopoiesis J:204685
abnormal regulatory T cell physiology J:204685
abnormal T-helper 2 cell differentiation J:204685
abnormal T-helper 2 physiology J:204685
decreased CD4-positive, alpha-beta T cell number J:204685
dermatitis J:204685
enlarged lymph nodes J:204685
enlarged spleen J:204685
immune system phenotype J:204685
increased CD4-positive, alpha-beta T cell number J:204685
increased CD8-positive, alpha-beta T cell number J:204685
increased eosinophil cell number J:204685
increased IgA level J:204685
increased IgE level J:204685
increased IgG1 level J:204685
increased inflammatory response J:204685
increased interleukin-4 secretion J:204685
increased interleukin-5 secretion J:204685
increased interleukin-10 secretion J:204685
increased interleukin-13 secretion J:204685
increased interleukin-17 secretion J:204685
increased leukocyte cell number J:204685
increased regulatory T cell apoptosis J:204685
increased regulatory T cell number J:204685
lung inflammation J:204685
Itchtm1.1Alta/Itchtm1.1Alta
Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:204685
increased inflammatory response J:204685
Itchtm1b(EUCOMM)Hmgu/Itchtm1b(EUCOMM)Hmgu
(C57BL/6N-Itchtm1b(EUCOMM)Hmgu/H)
enlarged spleen J:211773
increased spleen weight J:211773
Itfg2Gt(OST215121)Lex/Itfg2Gt(OST215121)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal B cell activation J:205951
abnormal humoral immune response J:205951
abnormal splenocyte physiology J:205951
decreased B cell number J:205951
decreased IgE level J:205951
decreased IgG1 level J:205951
decreased IgG2a level J:205951
decreased IgG2b level J:205951
decreased IgG3 level J:205951
decreased lymphocyte cell number J:205951
decreased spleen germinal center number J:205951
decreased T follicular helper cell number J:205951
immune system phenotype J:205951
increased B cell number J:205951
spleen hyperplasia J:205951
Itga2btm1Tlr/Itga2btm1Tlr
(either: (involves: 129S1/Sv * 129X1/SvJ * BALB/c) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
enlarged spleen J:63961
Itga3tm1Son/Itga3tm1Son
Krt14tm1(cre)Wbm/Krt14+

(involves: 129P2/OlaHsd * FVB/N)
skin inflammation J:145988
Itga3tm1Son/Itga3tm1Son
Tg(KRT5-cre)5132Jlj/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA)
skin inflammation J:145988
Itga4tm1Mgin/Itga4tm1Mgin
(B6.129-Itga4tm1Mgin)
abnormal B cell physiology J:106471
abnormal lymphocyte physiology J:106471
abnormal T cell physiology J:106471
decreased monocyte cell number J:106471
decreased Peyer's patch number J:106471
impaired macrophage chemotaxis J:106471
Itga4tm1Mshi/Itga4tm1Mshi
(C57BL/6-Itga4tm1Mshi)
abnormal cellular extravasation J:144092
abnormal leukocyte adhesion J:144092
abnormal leukocyte migration J:144092
abnormal mononuclear cell morphology J:144092
decreased B cell number J:144092
decreased lymphocyte cell number J:144092
decreased T cell number J:144092
small Peyer's patches J:144092
Itga4tm1Tpa/Itga4tm1Tpa
Tg(Mx1-cre)1Cgn/?

(involves: 129S4/SvJaeSor * C57BL/6 * CBA)
abnormal B cell differentiation J:86861
decreased CD4-positive, alpha-beta T cell number J:86861
increased leukocyte cell number J:86861
Itga5tm1Hyn/Itga5+
Nischedsn/Nisch+

(C3H.Cg-Nischedsn Itga5tm1Hyn)
increased susceptibility to otitis media J:244907
Itga5tm1Hyn/Itga5+
Nischedsn/Nischedsn

(C3H.Cg-Nischedsn Itga5tm1Hyn)
increased susceptibility to otitis media J:244907
Itga6tm1Son/Itga6tm1Son
(involves: 129P2/OlaHsd * FVB)
abnormal lymph node morphology J:50235
abnormal T cell physiology J:50235
decreased T cell number J:50235
Itga9tm1Des/Itga9tm1Des
(involves: 129S4/SvJae * C57BL/6)
abnormal lymph circulation J:63038
Itga11em1(IMPC)H/Itga11em1(IMPC)H
(C57BL/6N-Itga11em1(IMPC)H/H)
decreased spleen weight J:211773
Itgadtm1.1Zimm/Itgadtm1.1Zimm
(involves: 129S6/SvEvTac * C57BL/6)
abnormal immune system physiology J:130908
abnormal macrophage physiology J:130908
abnormal susceptibility to infection J:130908
decreased susceptibility to parasitic infection J:130908
increased circulating interleukin-12 level J:130908
increased spleen weight J:130908
increased susceptibility to bacterial infection J:130908
Itgadtm1Bll/Itgadtm1Bll
(B6.129S7-Itgadtm1Bll)
abnormal lymphocyte cell number J:90954
abnormal T cell activation J:90954
abnormal T cell subpopulation ratio J:90954
decreased CD4-positive, alpha-beta T cell number J:90954
decreased T cell proliferation J:90954
increased CD8-positive, alpha-beta T cell number J:90954
Itgaetm1b(EUCOMM)Wtsi/Itgaetm1b(EUCOMM)Wtsi
(C57BL/6N-Itgaetm1b(EUCOMM)Wtsi/H)
decreased large unstained cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
Itgaetm1Cmp/Itgaetm1Cmp
(involves: 129S2/SvPas * BALB/c)
decreased lymphocyte cell number J:55333
decreased T cell number J:55333
Itgaltm1.1Mshi/Itgaltm1.1Mshi
(involves: C57BL/6)
abnormal diapedesis J:168533
abnormal leukocyte adhesion J:168533
abnormal leukocyte migration J:168533
decreased lymphocyte cell number J:168533
enhanced leukocyte tethering or rolling J:168533
small lymph nodes J:168533
Itgaltm1Bll/Itgal+
(involves: 129S7/SvEvBrd)
abnormal CD4-positive, alpha-beta T cell physiology J:267548
Itgaltm1Bll/Itgaltm1Bll
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal cellular extravasation J:83226
abnormal leukocyte adhesion J:83226
abnormal leukocyte migration J:83226
increased eosinophil cell number J:83226
increased leukocyte cell number J:83226
increased monocyte cell number J:83226
increased neutrophil cell number J:83226
Itgaltm1Bll/Itgaltm1Bll
(B6.129S7-Itgaltm1Bll)
abnormal leukocyte adhesion J:100242
abnormal leukocyte tethering or rolling J:100242
decreased T cell proliferation J:90954
impaired natural killer cell mediated cytotoxicity J:90954
increased leukocyte cell number J:100242
increased neutrophil cell number J:100242
Itgaltm1Bll/Itgaltm1Bll
(B6.129S7-Itgaltm1Bll/J)
abnormal inflammatory response J:113463
Itgaltm1Bll/Itgaltm1Bll
(involves: 129S7/SvEvBrd)
abnormal CD4-positive, alpha-beta T cell physiology J:267548
abnormal cellular extravasation J:141063
abnormal leukocyte adhesion J:141063
abnormal neutrophil physiology J:141063
Itgaltm1Hlz/Itgaltm1Hlz
(involves: 129P2/OlaHsd)
abnormal cellular extravasation J:99286
abnormal humoral immune response J:99286
abnormal leukocyte adhesion J:99286
abnormal T cell activation J:99286
decreased cytotoxic T cell cytolysis J:99286
decreased lymphocyte cell number J:99286
decreased neutrophil cell number J:99286
spleen hyperplasia J:99286
Itgaltm1Hogg/Itgaltm1Hogg
(involves: 129P2/OlaHsd)
abnormal leukocyte adhesion J:82587
abnormal leukocyte migration J:82587
abnormal lymph node morphology J:82587
decreased B cell number J:82587
decreased CD4-positive, alpha-beta T cell number J:82587
decreased CD8-positive, alpha-beta T cell number J:82587
decreased lymphocyte cell number J:82587
enlarged spleen J:82587
increased CD4-positive, alpha-beta T cell number J:82587
increased CD8-positive, alpha-beta T cell number J:82587
small lymph nodes J:82587
Itgaltm1Mak/Itgal+
(B6.129P2-Itgaltm1Mak)
decreased susceptibility to endotoxin shock J:123460
Itgaltm1Mak/Itgaltm1Mak
(B6.129P2-Itgaltm1Mak)
decreased susceptibility to endotoxin shock J:123460
impaired natural killer cell mediated cytotoxicity J:110889
increased circulating interleukin-2 level J:123460
increased circulating interleukin-10 level J:123460
increased circulating tumor necrosis factor level J:123460
Itgaltm1Wpfl/Itgaltm1Wpfl
(involves: 129)
abnormal cytotoxic T cell physiology J:37160
abnormal leukocyte physiology J:37160
abnormal lymphocyte physiology J:37160
immune system phenotype J:37160
lymph node hyperplasia J:37160
Itgamm1Btlr/Itgam+
(C57BL/6J-Itgamm1Btlr)
abnormal dendritic cell number J:236681
decreased macrophage cell number J:236681
decreased neutrophil cell number J:236681
increased plasmacytoid dendritic cell number J:236681
Itgamm1Btlr/Itgamm1Btlr
(C57BL/6J-Itgamm1Btlr)
abnormal dendritic cell number J:236681
decreased macrophage cell number J:236681
decreased neutrophil cell number J:236681
increased plasmacytoid dendritic cell number J:236681
Itgamm2Btlr/Itgamm2Btlr
(C57BL/6J-Itgamm2Btlr)
decreased CD11b-high dendritic cell number J:272532
Itgamm3Btlr/Itgamm3Btlr
(C57BL/6J-Itgamm3Btlr)
decreased CD11b-high dendritic cell number J:272533
Itgamtm1Bll/Itgamtm1Bll
(B6.129S7-Itgamtm1Bll)
abnormal leukocyte adhesion J:100242
abnormal lymphocyte cell number J:90954
abnormal T cell activation J:90954
abnormal T cell subpopulation ratio J:90954
decreased CD4-positive, alpha-beta T cell number J:90954
decreased T cell proliferation J:90954
increased CD8-positive, alpha-beta T cell number J:90954
increased leukocyte cell number J:100242
increased neutrophil cell number J:100242
increased susceptibility to bacterial infection J:94855
Itgamtm1Bll/Itgamtm1Bll
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal cellular extravasation J:83226
abnormal leukocyte adhesion J:83226
abnormal leukocyte migration J:83226
abnormal neutrophil physiology J:39092
decreased eosinophil cell number J:83226
impaired neutrophil phagocytosis J:39092
Itgamtm1Myd/Itgamtm1Myd
(involves: 129S4/SvJae * BALB/c * C57BL/6)
abnormal leukocyte adhesion J:38052
impaired neutrophil phagocytosis J:38052
increased eosinophil cell number J:38052
increased neutrophil cell number J:38052
Itgamtm1Myd/Itgamtm1Myd
(involves: 129S4/SvJae * C57BL/6)
decreased neutrophil cell number J:103873
Itgamtm1Myd/Itgamtm1Myd
(B6.129S4-Itgamtm1Myd)
abnormal inflammatory response J:113463
abnormal neutrophil morphology J:113463
abnormal neutrophil physiology J:113463
Itgamtm1Myd/Itgamtm1Myd
(involves: 129S4/SvJae)
impaired leukocyte tethering or rolling J:198197
impaired neutrophil phagocytosis J:155479
Itgamtm1Myd/Itgamtm1Myd
Syktm1Tyb/Syktm1.2Tara
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6)
impaired granulocyte bactericidal activity J:155479
Itgamtm1Rws/Itgamtm1Rws
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal macrophage physiology J:65847
Itgavtm1Blb/Itgavtm1Blb
Itgb1tm1Ref/Itgb1tm1Ref
Itgb2tm2Bay/Itgb2tm2Bay
Itgb7tm1Cgn/Itgb7tm1Cgn
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * CBA)
abnormal cellular extravasation J:134784
abnormal dendritic cell physiology J:134784
immune system phenotype J:134784
Itgavtm2Hyn/Itgavtm2.1Hyn
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * FVB)
colitis J:125508
impaired macrophage phagocytosis J:125508
increased autoantibody level J:125508
Itgavtm2Hyn/Itgavtm2.1Hyn
Tg(Nes-cre)1Kln/0

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB * SJL)
increased susceptibility to bacterial infection induced morbidity/mortality J:94376
Itgavtm2Hyn/Itgavtm2.1Hyn
Tg(Tek-cre)1Ywa/?

(involves: 129S2/SvPas * C57BL/6 * FVB * SJL)
abnormal dendritic cell differentiation J:125508
abnormal immune system morphology J:125508
abnormal immune system physiology J:125508
abnormal interferon level J:125508
abnormal interleukin level J:125508
abnormal leukocyte morphology J:125508
abnormal tumor necrosis factor level J:125508
colitis J:125508
decreased regulatory T cell number J:125508
enlarged mesenteric lymph nodes J:125508
enlarged Peyer's patches J:125508
impaired macrophage phagocytosis J:125508
increased autoantibody level J:125508
increased inflammatory response J:125508
increased regulatory T cell number J:125508
large intestinal inflammation J:125508
ItgaxM1Btlr/Itgax+
(C57BL/6J-ItgaxM1Btlr)
decreased dendritic cell number J:236684
increased plasmacytoid dendritic cell number J:236684
ItgaxM1Btlr/ItgaxM1Btlr
(C57BL/6J-ItgaxM1Btlr)
decreased dendritic cell number J:236684
increased plasmacytoid dendritic cell number J:236684
Itgaxtm1.1(HBEGF)Ktak/Itgax+
(involves: 129S4/SvJae * C57BL/6)
abnormal response to infection J:162397
Itgaxtm1Bll/Itgaxtm1Bll
(B6.129S7-Itgaxtm1Bll)
decreased interferon-gamma secretion J:122187
decreased interleukin-17 secretion J:122187
decreased susceptibility to experimental autoimmune encephalomyelitis J:122187
decreased tumor necrosis factor secretion J:122187
increased interleukin-2 secretion J:122187
increased interleukin-12 secretion J:122187
increased susceptibility to bacterial infection J:94855
increased T cell proliferation J:122187
Itgb1tm1Ref/Itgb1tm1Ref
Tg(KRT5-cre)5132Jlj/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J)
skin inflammation J:65038
Itgb2M1Btlr/Itgb2M1Btlr
(C57BL/6J-Itgb2M1Btlr)
abnormal NK cell differentiation J:139559
decreased interferon-gamma secretion J:139559
immune system phenotype J:139559
Itgb2m2Btlr/Itgb2m2Btlr
(C57BL/6J-Itgb2m2Btlr)
increased interferon-beta secretion J:265125
Itgb2m3Btlr/Itgb2m3Btlr
(C57BL/6J-Itgb2m3Btlr)
abnormal cytotoxic T cell cytolysis J:265126
decreased B cell number J:265126
decreased CD4-positive, alpha-beta T cell number J:265126
decreased CD8-positive, alpha-beta T cell number J:265126
decreased dendritic cell number J:265126
decreased IgG level J:265126
decreased macrophage cell number J:265126
decreased neutrophil cell number J:265126
decreased single-positive T cell number J:265126
impaired humoral immune response J:265126
impaired natural killer cell mediated cytotoxicity J:265126
increased dendritic cell number J:265126
increased effector memory CD4-positive, alpha-beta T cell number J:265126
increased IgE level J:265126
increased NK T cell number J:265126
Itgb2M4Btlr/Itgb2M4Btlr
(C57BL/6J-Itgb2M4Btlr)
abnormal T cell differentiation J:272843
increased effector memory CD4-positive, alpha-beta T cell number J:272843
Itgb2m5Btlr/Itgb2m5Btlr
(C57BL/6J-Itgb2m5Btlr)
increased B-1b cell number J:272844
Itgb2tm1.1Arte/Itgb2tm1.1Arte
(involves: C57BL/6NTac)
abnormal T cell physiology J:202261
decreased T cell proliferation J:202261
enlarged spleen J:202261
increased B cell number J:202261
increased dendritic cell number J:202261
increased neutrophil cell number J:202261
increased T cell number J:202261
lymph node hypoplasia J:202261
Itgb2tm1Bay/Itgb2tm1Bay
(involves: 129S7/SvEvBrd)
decreased inflammatory response J:13599
increased granulocyte number J:13599
increased leukocyte cell number J:13599, J:32126
increased lymphocyte cell number J:13599
Itgb2tm1Bay/Itgb2tm1Bay
(involves: 129S7/SvEvBrd * PL/J)
abnormal cytokine level J:109598
abnormal spleen morphology J:32126
abnormal T cell activation J:109598
dermatitis J:109598, J:32126
enlarged lymph nodes J:32126
increased basophil cell number J:32126
increased eosinophil cell number J:32126
increased interferon-gamma secretion J:109598
increased leukocyte cell number J:32126
increased lymphocyte cell number J:32126
increased monocyte cell number J:32126
increased neutrophil cell number J:32126
increased T cell number J:109598
increased T-helper 1 cell number J:109598
myeloid hyperplasia J:32126
Itgb2tm1Bay/Itgb2tm1Bay
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal spleen red pulp morphology J:13599
myeloid hyperplasia J:13599
Itgb2tm1Bay/Itgb2tm1Bay
(involves: 129S7/SvEvBrd * C57BL/6J * PL/J)
dermatitis J:84126
Itgb2tm1Bay/Itgb2tm1Bay
Psrs1PL/J/Psrs1PL/J

(B6.Cg-(D10Mit126-D10Mit38) Itgb2tm1Bay)
rheumatoid arthritis J:134251
Itgb2tm1Bay/Itgb2tm1Bay
Psrs1PL/J/Psrs1PL/J

(B6.Cg-(D10Mit75-D10Mit271) Itgb2tm1Bay)
rheumatoid arthritis J:134251
Itgb2tm1Bay/Itgb2tm2Bay
(PL.129S7-Itgb2tm1Bay Itgb2tm2Bay)
dermatitis J:84126
Itgb2tm1Bay/Itgb2tm2Bay
(involves: 129S7/SvEvBrd * C57BL/6J * PL/J)
dermatitis J:84126
Itgb2tm2Bay/Itgb2tm2Bay
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal immune system cell morphology J:48542
abnormal leukocyte physiology J:48542
abnormal lymph organ size J:48542
abnormal neutrophil morphology J:48542
abnormal neutrophil physiology J:48542
abnormal T cell proliferation J:48542
conjunctivitis J:48542
dermatitis J:48542
enlarged lymph nodes J:48542
enlarged spleen J:48542
increased circulating interleukin-3 level J:48542
increased circulating interleukin-6 level J:48542
increased IgA level J:48542
increased IgG level J:48542
increased IgM level J:48542
increased immunoglobulin level J:48542
increased inflammatory response J:48542
increased leukocyte cell number J:48542
increased lymphocyte cell number J:48542
increased monocyte cell number J:48542
increased neutrophil cell number J:48542
increased susceptibility to bacterial infection J:48542
myeloid hyperplasia J:48542
Itgb2tm2Bay/Itgb2tm2Bay
(involves: 129S7/SvEvBrd)
decreased T cell proliferation J:90954
Itgb2tm2Bay/Itgb2tm2Bay
(B6.129S7-Itgb2tm2Bay)
abnormal leukocyte adhesion J:83226
abnormal leukocyte migration J:83226
decreased susceptibility to bacterial infection J:94855
increased eosinophil cell number J:83226
increased leukocyte cell number J:83226
increased lymphocyte cell number J:83226
increased monocyte cell number J:83226
increased neutrophil cell number J:83226
Itgb2tm2Bay/Itgb2tm2Bay
(involves: 129S7/SvEvBrd * C57BL/6)
decreased acute inflammation J:112286
impaired neutrophil recruitment J:112286
increased neutrophil cell number J:112286
Itgb2tm2Bay/Itgb2tm2Bay
(PL.129S7-Itgb2tm2Bay)
decreased susceptibility to type IV hypersensitivity reaction J:109598
Itgb2ltm1Jhws/Itgb2ltm1Jhws
(involves: 129/Sv * C57BL/6)
immune system phenotype J:118477
Itgb3tm1Hyn/Itgb3tm1.1Wlbcr
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
abnormal osteoclast differentiation J:224675
abnormal osteoclast morphology J:224675
decreased osteoclast cell number J:224675
Itgb3tm1Hyn/Itgb3tm1.1Wlbcr
Tg(Pf4-icre)Q3Rsko/0

(involves: 129S2/SvPas * C57BL/6)
enlarged spleen J:224675
Itgb3tm1Hyn/Itgb3tm1Hyn
(involves: 129S2/SvPas * C57BL/6)
abnormal macrophage physiology J:119666
dermatitis J:52262
enlarged spleen J:52262
impaired macrophage chemotaxis J:119666
increased monocyte cell number J:119666
myositis J:119666
Itgb3tm1Hyn/Itgb3tm1Hyn
(involves: 129S2/SvPas)
abnormal osteoclast morphology J:60672
abnormal osteoclast physiology J:60672
decreased macrophage cell number J:96049
increased osteoclast cell number J:60672
Itgb3tm1Hyn/Itgb3tm1Hyn
(involves: 129S2/SvPas * BALB/c)
immune system phenotype J:131241
increased IgG level J:131241
Itgb4tm1Son/Itgb4tm1Son
(129P2/OlaHsd-Itgb4tm1Son)
immune system phenotype J:33713
Itgb4tm2Son/Itgb4tm2Son
Tg(KRT14-cre)8Brn/0

(involves: 129P2/OlaHsd * FVB/N)
ear inflammation J:96543
Itgb5tm1a(EUCOMM)Wtsi/Itgb5tm1a(EUCOMM)Wtsi
(C57BL/6N-Itgb5tm1a(EUCOMM)Wtsi/Ics)
increased leukocyte cell number J:165965
Itgb6em1(IMPC)Ccpcz/Itgb6em1(IMPC)Ccpcz
(C57BL/6NCrl-Itgb6em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Itgb6tm1Des/Itgb6tm1Des
(involves: 129S4/SvJae * C57BL/6J)
respiratory system inflammation J:33139
Itgb6tm1Des/Itgb6tm1Des
(involves: 129S4/SvJae)
abnormal immune system physiology J:120085
absent Langerhans cell J:120085
decreased Langerhans cell number J:120085
Itgb6tm1Des/Itgb6tm1Des
(involves: 129S4/SvJae * C57BL/6 * SJL)
respiratory system inflammation J:51592
Itgb6tm1Des/Itgb6tm1Des
Mmp12tm1Sds/Mmp12tm1Sds

(involves: 129/Sv * 129T2/SvEms)
lung inflammation J:89578
Itgb6tm1Des/Itgb6tm1Des
Tg(SFTPC-ITGB6)1Des/?

(involves: 129S4/SvJae * C57BL/6 * SJL)
respiratory system inflammation J:51592
Itgb7tm1Cgn/Itgb7tm1Cgn
(involves: C57BL/6)
abnormal gut-associated lymphoid tissue morphology J:34306
abnormal immune system morphology J:34306
abnormal immune system physiology J:34306
abnormal lymphocyte physiology J:34306
abnormal Peyer's patch follicle morphology J:34306
abnormal response to infection J:62733
abnormal uterine NK cell morphology J:44813
decreased B cell number J:34306
decreased CD4-positive, alpha-beta T cell number J:34306
decreased eosinophil cell number J:62733
decreased mast cell number J:62733
immune system phenotype J:111227
impaired leukocyte tethering or rolling J:34306
increased susceptibility to parasitic infection J:90262
increased uterine NK cell number J:44813
small Peyer's patches J:34306
Itgb7tm1Cgn/Itgb7tm1Cgn
(C57BL/6-Itgb7tm1Cgn/J)
abnormal leukocyte migration J:127413
colitis J:127413
Itgb7tm1Cgn/Itgb7tm1Cgn
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * C57BL/6)
abnormal inflammatory response J:136667
arthritis J:136667
Itgb7tm1Mshi/Itgb7tm1Mshi
(involves: C57BL/6)
abnormal leukocyte adhesion J:127413
abnormal leukocyte migration J:127413
colitis J:127413
small Peyer's patches J:127413
Itkem1(IMPC)Mbp/Itkem1(IMPC)Mbp
(C57BL/6N-Itkem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Itkm1Btlr/Itkm1Btlr
(C57BL/6J-Itkm1Btlr)
abnormal CD4-positive, alpha-beta T cell physiology J:236673
abnormal CD8-positive, alpha-beta T cell physiology J:236673
increased CD8-positive, alpha-beta memory T cell proliferation J:236673
increased IgE level J:236673
Itkm2Btlr/Itkm2Btlr
(C57BL/6J-Itkm2Btlr)
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254826
decreased CD8-positive, alpha-beta memory T cell number J:254826
decreased CD8-positive, naive alpha-beta T cell number J:254826
increased B cell number J:254826
increased central memory CD4-positive, alpha-beta T cell number J:254826
increased central memory CD8 positive, alpha-beta T cell number J:254826
increased effector memory CD4-positive, alpha-beta T cell number J:254826
Itktm1Lex/Itktm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased CD4-positive, alpha-beta T cell number J:103485
decreased CD8-positive, alpha-beta T cell number J:103485
increased B cell number J:103485
Itktm1Litt/Itktm1Litt
(involves: 129S4/SvJae * C57BL/6J)
decreased B cell number J:31230
decreased CD4-positive, alpha-beta T cell number J:31230
decreased T cell number J:31230
decreased T cell proliferation J:31230
immune system phenotype J:31230
Itktm1Litt/Itktm1Litt
(involves: 129S4/SvJae)
decreased T cell proliferation J:54449
increased susceptibility to parasitic infection J:54449
Itktm1Litt/Itktm1Litt
(involves: 129S4/SvJae * C57BL/6)
abnormal CD8-positive, alpha-beta T cell differentiation J:111786
abnormal thymus cell ratio J:111786
decreased CD8-positive, alpha-beta T cell number J:111786
Itktm1Litt/Itktm1Litt
(B6.129S4-Itktm1Litt)
abnormal positive T cell selection J:141390
abnormal T cell morphology J:141390
decreased interleukin-2 secretion J:141390
decreased T cell number J:141390
decreased T cell proliferation J:141390
increased double-negative T cell number J:141390
Itktm1Litt/Itktm1Litt
Tg(DO11.10)10Dlo/0

(involves: 129S4/SvJae * BALB/c * C3H * C57BL/6J)
abnormal T-helper 2 physiology J:129883
Itktm1Litt/Itktm1Litt
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129S4/SvJae * C57BL/6 * DBA/2J)
abnormal positive T cell selection J:31230
decreased CD4-positive, alpha-beta T cell number J:31230
increased double-positive T cell number J:31230
Itktm1Litt/Itktm1Litt
Tg(TcrAND)53Hed/0

(involves: 129S4/SvJae * C57BL/6 * SJL)
abnormal lymphocyte morphology J:31230
decreased CD4-positive, alpha-beta T cell number J:31230
increased double-negative T cell number J:31230
Itktm1Litt/Itktm1Litt
Txktm1Pls/Txktm1Pls

(involves: 129S4/SvJae * 129S6/SvEvTac)
decreased CD4-positive, alpha-beta T cell number J:54449
decreased single-positive T cell number J:54449
decreased T cell proliferation J:54449
increased susceptibility to parasitic infection J:54449
Itktm1Litt/Itktm1Litt
Vav1tm2Bbd/Vav1tm2Bbd

(B6.129-Itktm1Litt Vav1tm2Bbd)
abnormal CD4-positive T cell differentiation J:141390
abnormal CD8-positive, alpha-beta T cell differentiation J:141390
abnormal positive T cell selection J:141390
abnormal T cell morphology J:141390
abnormal T cell physiology J:141390
decreased CD4-positive, alpha-beta T cell number J:141390
decreased CD8-positive, alpha-beta T cell number J:141390
decreased double-positive T cell number J:141390
decreased T cell number J:141390
decreased thymocyte number J:141390
increased B cell number J:141390
increased T cell apoptosis J:141390
Itktm1Ljb/Itktm1Ljb
(B6.129-Itktm1Ljb)
abnormal NK T cell morphology J:120689
decreased NK T cell number J:120689
Itktm1Ljb/Itktm1Ljb
(involves: 129 * C57BL/6)
abnormal T cell activation J:48231
decreased CD4-positive, alpha-beta T cell number J:48231
decreased interleukin-2 secretion J:48231
Itktm1Ljb/Itktm1Ljb
(B10.129-Itktm1Ljb)
abnormal CD8-positive, alpha-beta T cell differentiation J:113408
abnormal CD8-positive, alpha-beta T cell physiology J:113408
abnormal gamma-delta T cell morphology J:148531
decreased CD4-positive, alpha-beta T cell number J:123795
decreased interferon-gamma secretion J:148531
increased CD8-positive, alpha-beta T cell number J:113408, J:123795
increased germinal center B cell number J:148531
increased IgE level J:148531
increased interferon-gamma secretion J:113408
increased interleukin-4 secretion J:148531
increased interleukin-10 secretion J:148531
increased interleukin-13 secretion J:148531
increased mature gamma-delta T cell number J:148531
increased memory T cell number J:113408
Itktm1Ljb/Itktm1Ljb
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra5CC7,Tcrb5CC7)IWep/?

(involves: 129 * C57BL/10)
abnormal CD4-positive T cell differentiation J:93606
decreased interferon-gamma secretion J:93606
decreased interleukin-4 secretion J:93606
decreased interleukin-5 secretion J:93606
decreased interleukin-10 secretion J:93606
Itktm1Ljb/Itktm1Ljb
Tcrdtm1Mom/Tcrdtm1Mom

(involves: 129 * C57BL/6 * C57BL/10)
immune system phenotype J:148531
Itktm1Ljb/Itktm1Ljb
Tg(Tcra2B4)1Mmd/?
Tg(Tcrb2B4)1Mmd/?

(involves: C3H/HeJ * C57BL/6 * C57BL/10)
decreased CD4-positive, alpha-beta T cell number J:123795
Itktm1Ljb/Itktm1Ljb
Tg(Tcra5CC7,Tcrb5CC7)IWep/?

(involves: 129 * C57BL/10)
decreased CD4-positive, alpha-beta T cell number J:123795
Itktm1Ljb/Itktm1Ljb
Tg(TcraTcrb)1100Mjb/?

(involves: 129 * C57BL/6 * C57BL/10)
immune system phenotype J:113408
Itktm1Ljb/Itktm1Ljb
Txktm1Pls/Txktm1Pls

(B6.129-Txktm1Pls Itktm1Ljb)
abnormal CD8-positive, alpha-beta T cell physiology J:113408
increased CD8-positive, alpha-beta T cell number J:113408
increased interferon-gamma secretion J:113408
increased memory T cell number J:113408
Itln1em1Cya/Itln1em1Cya
(involves: C57BL/6)
abnormal cytokine level J:282124
abnormal osteoclast physiology J:282124
increased circulating interleukin-1 alpha level J:282124
increased circulating interleukin-6 level J:282124
increased circulating interleukin-10 level J:282124
increased circulating tumor necrosis factor level J:282124
increased osteoclast cell number J:282124
Itm2cem1Nutt/Itm2cem1Nutt
Prdm1tm1Nutt/Prdm1+

(involves: C57BL/6 * C57BL/6J)
immune system phenotype J:265892
ItpkbT-less/ItpkbT-less
(C57BL/6-ItpkbT-less)
abnormal T cell physiology J:89286
arrested T cell differentiation J:89286
Itpkbtm1Ssch/Itpkbtm1Ssch
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal thymocyte activation J:86257
abnormal thymus involution J:86257
absent CD4-positive, alpha-beta T cells J:86257
absent CD8-positive, alpha-beta T cells J:86257
absent T cells J:86257
absent thymus medulla J:86257
arrested T cell differentiation J:86257
decreased IgG1 level J:86257
decreased IgG2a level J:86257
decreased IgG2b level J:86257
decreased IgG level J:86257
increased double-positive T cell number J:86257
increased susceptibility to parasitic infection J:86257
Itpkbtm1Ssch/Itpkbtm1Ssch
Itpkctm1Ssch/Itpkctm1Ssch

(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal thymocyte activation J:86257
absent CD4-positive, alpha-beta T cells J:86257
absent CD8-positive, alpha-beta T cells J:86257
arrested T cell differentiation J:86257
Itpr3em1(IMPC)Mbp/Itpr3em1(IMPC)Mbp
(C57BL/6N-Itpr3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Ity2C57BL/6J/Ity2MOLF/EiJ
(involves: C57BL/6J * MOLF/Ei)
decreased susceptibility to bacterial infection J:45962
Ity2MOLF/EiJ/Ity2MOLF/EiJ
(involves: C57BL/6J * MOLF/Ei)
decreased susceptibility to bacterial infection J:126552, J:45962
Ity2aMOLF/EiJ/Ity2aMOLF/EiJ
(involves: C57BL/6J * MOLF/Ei)
decreased susceptibility to bacterial infection J:126552
Ity2bMOLF/EiJ/Ity2bMOLF/EiJ
(involves: C57BL/6J * MOLF/Ei)
decreased susceptibility to bacterial infection J:126552
Ity3C57BL/6J/Ity3C57BL/6J
(involves: C57BL/6J * MOLF/Ei)
decreased susceptibility to bacterial infection J:45962
Ity3C57BL/6J/Ity3MOLF/EiJ
(involves: C57BL/6J * MOLF/Ei)
decreased susceptibility to bacterial infection J:45962
Ity3MOLF/EiJ/Ity3MOLF/EiJ
(involves: C57BL/6J * MOLF/Ei)
increased susceptibility to bacterial infection J:126552, J:45962
Ity3MOLF/EiJ/Ity3MOLF/EiJ
(B6.MOLF-Slc11a1r Ity3MOLF/EiJ)
abnormal cytokine secretion J:108692
Jade2em1(IMPC)Tcp/Jade2em1(IMPC)Tcp
(C57BL/6N-Jade2em1(IMPC)Tcp/Tcp)
small spleen J:211773
Jag2tm1Grid/Jag2tm1Grid
(involves: 129S1/Sv * C57BL/6J)
abnormal gamma-delta T cell differentiation J:46930
abnormal thymus medulla morphology J:46930
abnormal thymus morphology J:46930
decreased gamma-delta T cell number J:46930
Jagn1tm1c(EUCOMM)Hmgu/Jagn1tm1c(EUCOMM)Hmgu
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6N * C57BL/10 * CBA/Ca)
abnormal neutrophil morphology J:214828
abnormal neutrophil physiology J:214828
impaired neutrophil chemotaxis J:214828
impaired neutrophil recruitment J:214828
increased susceptibility to fungal infection J:214828
Jak1M1Mhda/Jak1+
(C3HeB/FeJ-Jak1M1Mhda)
abnormal plasma cell morphology J:199153
ear inflammation J:199153
enlarged spleen J:199153
increased anti-nuclear antigen antibody level J:199153
increased IgA level J:199153
increased IgG1 level J:199153
increased IgG2a level J:199153
increased IgM level J:199153
increased immunoglobulin level J:199153
increased plasma cell number J:199153
skin inflammation J:199153
Jak1tm1Rds/Jak1tm1Rds
(involves: 129)
abnormal B cell differentiation J:47300
abnormal lymphopoiesis J:47300
abnormal T cell differentiation J:47300
arrested B cell differentiation J:47300
decreased B cell number J:47300
decreased thymocyte number J:47300
increased double-negative T cell number J:47300
small thymus J:47300
Jak2tm1(JAK2)Argr/Jak2+
Dppa3tm1(cre)Peli/Dppa3+

(involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6)
increased leukocyte cell number J:233169
increased spleen weight J:233169
Jak2tm1(JAK2)Argr/Jak2+
Tg(Mx1-cre)1Cgn/0

(involves: 129S7/SvEvBrd * C57BL/6 * CBA)
decreased leukocyte cell number J:164539
enlarged spleen J:164539
increased leukocyte cell number J:164539
Jak2tm1.1Ble/Jak2+
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca)
abnormal cytokine level J:257910
enlarged spleen J:257910
increased granulocyte number J:257910
increased leukocyte cell number J:257910
increased neutrophil cell number J:257910
Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
(involves: 129S2/SvPas * C57BL/6)
abnormal spleen morphology J:163497
decreased spleen white pulp amount J:163497
enlarged spleen J:163497
increased granulocyte number J:163497
increased leukocyte cell number J:163497
increased lymphocyte cell number J:163497
increased monocyte cell number J:163497
increased spleen red pulp amount J:163497
Jak2tm1.2Ble/Jak2+
(involves: 129S6/SvEvTac * C57BL/6 * FVB/N)
abnormal spleen morphology J:160883
abnormal spleen red pulp morphology J:160883
enlarged spleen J:160883
increased leukocyte cell number J:160883
Jak2tm1.2Ble/Jak2+
Picalmtm1.1Tmae/Picalmtm1.1Tmae
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * CBA * SJL)
decreased CD4-positive, alpha-beta T cell number J:220728
decreased CD8-positive, alpha-beta T cell number J:220728
Jak2tm1Mohi/Jak2+
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal spleen red pulp morphology J:183821
abnormal spleen white pulp morphology J:183821
decreased B cell number J:183821
enlarged spleen J:183821
increased leukocyte cell number J:183821
increased neutrophil cell number J:183821
increased spleen red pulp amount J:183821
increased spleen weight J:183821
myeloid hyperplasia J:183821
spleen fibrosis J:183821
Jak2tm1Mohi/Jak2tm1Mohi
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal spleen red pulp morphology J:183821
abnormal spleen white pulp morphology J:183821
decreased B cell number J:183821
decreased spleen white pulp amount J:183821
enlarged spleen J:183821
increased leukocyte cell number J:183821
increased neutrophil cell number J:183821
increased spleen red pulp amount J:183821
increased spleen weight J:183821
myeloid hyperplasia J:183821
spleen fibrosis J:183821
Jak2tm2.1Jlvl/Jak2+
Tg(Vav1-cre)#Cgp/0

(involves: 129S2/SvPas * C57BL/6NTac)
abnormal myelopoiesis J:202234
decreased B cell number J:202234
enlarged spleen J:202234
increased granulocyte number J:202234
increased leukocyte cell number J:202234
increased spleen weight J:202234
myeloid hyperplasia J:202234
spleen fibrosis J:202234
Jak2tm2.2Jlvl/Jak2+
(involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac * SJL)
enlarged spleen J:202234
increased leukocyte cell number J:202234
Jak3bfy/Jak3bfy
(C57BL/6JSfdAnu-Jak3bfy/AnuApb)
abnormal lymphopoiesis J:104190
abnormal T cell subpopulation ratio J:104190
decreased B cell number J:104190
decreased lymphocyte cell number J:104190
decreased T cell number J:104190
decreased thymocyte number J:104190
small thymus J:104190
Jak3em1(IMPC)Mbp/Jak3+
(C57BL/6N-Jak3em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Jak3m1Btlr/Jak3m1Btlr
(C57BL/6J-Jak3m1Btlr)
abnormal T cell subpopulation ratio J:217795
decreased IgG level J:217795
decreased NK cell number J:217795
decreased response to antigen J:217795
decreased single-positive T cell number J:217795
decreased T cell number J:217795
impaired humoral immune response J:217795
increased effector memory CD4-positive, alpha-beta T cell number J:217795
increased effector memory CD8-positive, alpha-beta T cell number J:217795
increased IgE level J:217795
increased neutrophil cell number J:217795
increased single-positive T cell number J:217795
increased susceptibility to Herpesvirales infection J:217795
Jak3m1J/Jak3m1J
(B6.Cg-Crb1+ Jak3m1J/Boc)
decreased spleen weight J:265859
decreased thymus weight J:265859
small spleen J:265859
small thymus J:265859
Jak3M1Pgrs/Jak3+
(involves: C57BL/6J * C57BL/10J)
decreased susceptibility to parasitic infection induced morbidity/mortality J:185217
Jak3M1Pgrs/Jak3M1Pgrs
(involves: C57BL/6J * C57BL/10J)
absent B cells J:185217
decreased B cell number J:185217
decreased interferon-gamma secretion J:185217
decreased NK cell number J:185217
decreased susceptibility to parasitic infection induced morbidity/mortality J:185217
enlarged spleen J:185217
increased CD4-positive, alpha-beta T cell number J:185217
increased CD8-positive, alpha-beta T cell number J:185217
increased susceptibility to bacterial infection J:185217
increased susceptibility to bacterial infection induced morbidity/mortality J:185217
small thymus J:185217
Jak3M1Pgrs/Jak3tm1Ljb
(involves: 129S4/SvJae * C57BL/6J * C57BL/10J)
decreased susceptibility to parasitic infection induced morbidity/mortality J:185217
Jak3m2Btlr/Jak3m2Btlr
(C57BL/6J-Jak3m2Btlr)
increased B cell number J:217796
increased memory B cell number J:217796
Jak3m3Btlr/Jak3m3Btlr
(C57BL/6J-Jak3m3Btlr)
abnormal T cell subpopulation ratio J:225935
decreased B cell number J:225935
decreased B-1 B cell number J:225935
decreased IgG level J:225935
decreased immature B cell number J:225935
decreased mature B cell number J:225935
decreased memory B cell number J:225935
decreased NK cell number J:225935
decreased single-positive T cell number J:225935
decreased T cell number J:225935
impaired humoral immune response J:225935
increased effector memory CD8-positive, alpha-beta T cell number J:225935
increased macrophage cell number J:225935
increased myeloid dendritic cell number J:225935
Jak3m4Btlr/Jak3m4Btlr
(C57BL/6J-Jak3m4Btlr)
increased CD4-positive, alpha-beta T cell number J:272398
Jak3M5Btlr/Jak3M5Btlr
(C57BL/6J-Jak3M5Btlr)
decreased NK T cell number J:272399
Jak3m6Btlr/Jak3m6Btlr
(C57BL/6J-Jak3m6Btlr)
decreased CD8-positive, alpha-beta T cell number J:272400
decreased IgG level J:272400
impaired humoral immune response J:272400
increased CD4-positive, alpha-beta T cell number J:272400
Jak3M7Btlr/Jak3M7Btlr
(C57BL/6J-Jak3M7Btlr)
abnormal CD4-positive T cell differentiation J:272401
Jak3m8Btlr/Jak3m8Btlr
(C57BL/6J-Jak3m8Btlr)
decreased B cell number J:274939
decreased B-1 B cell number J:274939
decreased B-2 B cell number J:274939
decreased CD4-positive, alpha-beta T cell number J:274939
decreased CD8-positive, alpha-beta T cell number J:274939
decreased CD8-positive, naive alpha-beta T cell number J:274939
decreased dendritic cell number J:274939
decreased IgG level J:274939
decreased IgM level J:274939
decreased response to antigen J:274939
decreased T cell number J:274939
impaired humoral immune response J:274939
increased B-1b cell number J:274939
increased effector memory CD4-positive, alpha-beta T cell number J:274939
Jak3tm1Flv/Jak3tm1Flv
(involves: 129S1/Sv)
abnormal T cell proliferation J:95794
arrested B cell differentiation J:95794
decreased CD8-positive, alpha-beta T cell number J:95794
enlarged spleen J:95794
increased CD4-positive, alpha-beta T cell number J:95794
small lymph nodes J:95794
thymus hypoplasia J:95794
Jak3tm1Jni/Jak3tm1Jni
Crlf2tm1Jni/Crlf2tm1Jni

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:89031
decreased B cell number J:89031
Jak3tm1Ljb/Jak3+
(involves: 129S4/SvJae)
abnormal leukocyte morphology J:56629
decreased lymphocyte cell number J:56629
increased leukocyte cell number J:56629
increased monocyte cell number J:56629
increased neutrophil cell number J:56629
Jak3tm1Ljb/Jak3tm1Ljb
(involves: 129S4/SvJae * C57BL/6)
abnormal B cell morphology J:29722
abnormal immune system physiology J:29722
abnormal leukocyte physiology J:90510
abnormal lymphocyte physiology J:90510
abnormal response to infection J:29722
abnormal splenic cell ratio J:29722
abnormal T cell activation J:29722
arrested B cell differentiation J:29722
decreased IgG level J:29722
decreased immature B cell number J:29722
decreased mature B cell number J:29722
decreased T cell proliferation J:29722
lymph node hypoplasia J:29722
small lymph nodes J:29722
small Peyer's patches J:29722
small thymus J:29722
spleen hypoplasia J:29722
thymus hypoplasia J:29722
Jak3tm1Ljb/Jak3tm1Ljb
(involves: 129S4/SvJae)
abnormal leukocyte morphology J:56629
abnormal myelopoiesis J:56629
abnormal spleen morphology J:56629
abnormal spleen white pulp morphology J:56629
abnormal T cell activation J:128694, J:56629
abnormal T cell differentiation J:64861
abnormal T cell physiology J:128694
abnormal thymus cell ratio J:128694
absent B cells J:128694
absent lymph nodes J:128694
chronic inflammation J:56629
decreased lymphocyte cell number J:56629
decreased T cell proliferation J:128694
decreased thymocyte number J:64861
enlarged spleen J:56629
increased leukocyte cell number J:56629
increased monocyte cell number J:56629
increased neutrophil cell number J:56629
thymus hypoplasia J:128694
Jak3tm1Ljb/Jak3tm1Ljb
(B6;129S4-Jak3tm1Ljb/J)
abnormal dendritic cell differentiation J:123902
abnormal dendritic cell morphology J:123902
abnormal dendritic cell physiology J:123902
abnormal splenic cell ratio J:123902
decreased CD4-positive, alpha-beta T cell number J:123902
decreased CD8-positive, alpha-beta T cell number J:123902
decreased myeloid dendritic cell number J:123902
Jak3tm1Ljb/Jak3tm1Ljb
Rag1tm1Mom/Rag1tm1Mom

(involves: 129S4/SvJae * 129S7/SvEvBrd)
abnormal splenic cell ratio J:56629
immune system phenotype J:56629
Jak3tm1Ljb/Jak3tm1Ljb
Tg(Lck-Jak3)1Ljb/0

(involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/10)
absent B cells J:128694
absent lymph nodes J:128694
decreased T cell proliferation J:128694
immune system phenotype J:128694
Jak3tm1Ljb/Jak3tm1Ljb
Tg(Lck-Jak3)2Ljb/0

(involves: 129S4/SvJae * C3H * C57BL/6)
abnormal T cell activation J:56629
enlarged spleen J:56629
immune system phenotype J:56629
increased leukocyte cell number J:56629
Jak3tm1Ljb/Jak3tm1Ljb
Tg(Lck-Jak3)2Ljb/0

(involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/10)
abnormal T cell activation J:128694
abnormal T cell physiology J:128694
absent B cells J:128694
absent lymph nodes J:128694
decreased T cell proliferation J:128694
immune system phenotype J:128694
Jak3tm1Tks/Jak3+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal leukocyte physiology J:31231
Jak3tm1Tks/Jak3tm1Tks
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:31231
abnormal CD4-positive, alpha beta T cell morphology J:31231
abnormal lymphopoiesis J:31231
abnormal mesenteric lymph node morphology J:31231
abnormal spleen periarteriolar lymphoid sheath morphology J:31231
abnormal spleen white pulp morphology J:31231
abnormal T cell morphology J:31231
abnormal T cell number J:31231
abnormal T cell physiology J:31231
abnormal thymus cortex morphology J:31231
abnormal thymus corticomedullary boundary morphology J:31231
abnormal thymus medulla morphology J:31231
absent Hassall's corpuscle J:31231
absent lymph nodes J:31231
absent NK cells J:31231
decreased B cell number J:31231
decreased pre-B cell number J:31231
decreased thymocyte number J:31231
small spleen J:31231
small thymus medulla J:31231
spleen hypoplasia J:31231
thymus cortex hypoplasia J:31231
thymus hypoplasia J:31231
Jak3wil/Jak3wil
(C57BL/6JSfdAnu-Jak3wil/Anu)
arrested B cell differentiation J:104190
decreased CD8-positive, alpha-beta T cell number J:104190
decreased leukocyte cell number J:104190
large intestinal inflammation J:104190
Jak3X887Y/Jak3X887Y
(Not Specified)
abnormal immune system organ morphology J:112658
abnormal lymph node morphology J:112658
abnormal lymphocyte morphology J:112658
abnormal spleen morphology J:112658
abnormal thymus morphology J:112658
Jak3X887Y/Jak3X887Y
Trdctm1Mal/Trdctm1Mal

(involves: C57BL/6)
immune system phenotype J:112658
Jakmip2em1(IMPC)J/Jakmip2em1(IMPC)J
(C57BL/6NJ-Jakmip2em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Jam3tm1Lex/Jam3tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
decreased neutrophil cell number J:145994
increased granulocyte number J:145994
Jam3tm1Rha/Jam3tm1Rha
(involves: 129P2/OlaHsd * C57BL/6)
increased granulocyte number J:121841
increased susceptibility to bacterial infection J:121841
lung inflammation J:121841
Jam3tm1Rha/Jam3tm1Rha
Tg(Tek-Jam3)1Maal/?

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA)
immune system phenotype J:121841
Jarid2jumonji/Jarid2jumonji
(C.129P2-Jarid2jumonji)
abnormal splenic cell ratio J:42772
abnormal thymus cell ratio J:42772
spleen hypoplasia J:42772
thymus hypoplasia J:42772
Jarid2jumonji/Jarid2jumonji
(either: B6.129P2-Jarid2jumonji or D2.129P2-Jarid2jumonji)
spleen hypoplasia J:42772
thymus hypoplasia J:42772
JchainMat1/?
MijuC3HeB/FeJ/MijuC57BL/6J

(involves: C3HeB/FeJ * C57BL/6J)
increased IgA level J:91062
Jchaintm1Jse/Jchaintm1Jse
(involves: 129X1/SvJ)
abnormal B cell physiology J:75843
increased IgA level J:34042, J:75843
Jchaintm1Jse/Jchaintm1Jse
(C.129X1-Jchaintm1Jse)
decreased susceptibility to Herpesvirales infection J:62298
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:62298
increased susceptibility to parasitic infection J:140515
Jchaintm1Tl/Jchaintm1Tl
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal humoral immune response J:71355
decreased IgG level J:71355
decreased IgM level J:71355
increased IgA level J:71355
Jchaintm2(Myc)Tl/Jchaintm2(Myc)Tl
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal humoral immune response J:71355
Jchaintm3Tl/Jchain+
(involves: 129P2/OlaHsd)
abnormal B cell physiology J:56158
abnormal immune cell physiology J:49168
decreased IgM level J:49168, J:56158
decreased plasma cell number J:49168
impaired complement classical pathway J:49168
increased IgA level J:56158
increased susceptibility to bacterial infection J:56158
Jchaintm3Tl/Jchaintm3Tl
(involves: 129P2/OlaHsd)
abnormal B cell physiology J:56158
abnormal immune cell physiology J:49168
decreased IgG level J:49168
decreased IgM level J:49168, J:56158
decreased plasma cell number J:49168, J:56158
impaired complement classical pathway J:49168
increased IgA level J:49168, J:56158
increased susceptibility to bacterial infection J:56158
Jdp2tm1Aki/Jdp2tm1Aki
(Not Specified)
abnormal neutrophil physiology J:191061
abnormal osteoclast differentiation J:191061
abnormal osteoclast morphology J:191061
increased susceptibility to bacterial infection J:191061
increased susceptibility to fungal infection J:191061
Jmjd4em1(IMPC)Wtsi/Jmjd4em1(IMPC)Wtsi
(C57BL/6N-Jmjd4em1(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Jmjd6tm1Gbf/Jmjd6tm1Gbf
(C57BL/6-Ptdsrtm1Gbf)
abnormal macrophage activation involved in immune response J:98905
small thymus J:102098
thymus hypoplasia J:102098
Jmjd8em1Kaso/Jmjd8em1Kaso
(C57BL/6-Jmjd8em1Kaso)
decreased circulating interleukin-1 beta level J:319518
decreased inflammatory response J:319518
Jph4tm1Hta/Jph4tm1Hta
(involves: 129S4/SvJae * C57BL/6J)
abnormal interleukin level J:230995
abnormal T cell activation J:230995
Junem1(IMPC)Mbp/Jun+
(C57BL/6N-Junem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Juntm1Rsjo/Juntm1Rsjo
Tg(KRT14-cre)8Brn/0

(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
increased incidence of corneal inflammation J:84743
Juntm4Wag/Juntm4Wag
Junbtm3Wag/Junbtm3Wag
Tg(Krt1-5-cre/ERT)1Ipc/0

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
arthritis J:116380
increased inflammatory response J:116380
skin inflammation J:116380
Juntm4Wag/Juntm4Wag
Tg(Sftpc-cre)1Blh/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal cytokine level J:179883
abnormal tumor necrosis factor level J:179883
lung inflammation J:179883
Junbtm1b(EUCOMM)Hmgu/Junb+
(C57BL/6N-Junbtm1b(EUCOMM)Hmgu/Bay)
increased spleen weight J:211773
Junbtm3Wag/Junbtm3Wag
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast morphology J:88126
Junbtm3Wag/Junbtm3Wag
Meox2tm1(cre)Sor/Meox2+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6)
abnormal osteoclast differentiation J:88126
decreased osteoclast cell number J:88126
Junbtm3Wag/Junbtm3Wag
Tg(KRT5-cre)1Tak/0

(involves: 129/Sv * 129P2/OlaHsd * C3H * C57BL/6)
dermatitis J:155575
glomerulonephritis J:155575
increased anti-histone antibody level J:155575
increased circulating interleukin-6 level J:155575
increased IgE level J:155575
increased inflammatory response J:155575
increased interleukin-6 secretion J:155575
increased plasma cell number J:155575
increased susceptibility to systemic lupus erythematosus J:155575
tubulointerstitial nephritis J:155575
Jundtm1Mya/Jundtm1Mya
(either: 129S2/SvPas or (involves: 129S2/SvPas * C57BL/6))
abnormal T-helper 2 physiology J:89085
immune system phenotype J:53906
increased susceptibility to endotoxin shock J:65879
increased T cell proliferation J:89085
liver inflammation J:65879
Juptm1.1Glr/Juptm1.1Glr
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+

(involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL)
abnormal interleukin level J:170618
heart inflammation J:170618
Kash5em1(IMPC)J/Kash5em1(IMPC)J
(C57BL/6NJ-Kash5em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Kat5tm1Jwl/Kat5+
Tg(IghMyc)22Bri/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL * C57BL/6 * SJL)
abnormal B cell physiology J:125164
Kat6atm1.1Glac/Kat6atm1.1Glac
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:148955
decreased immature B cell number J:148955
decreased pre-B cell number J:148955
decreased pro-B cell number J:148955
decreased spleen weight J:148955
decreased thymus weight J:148955
spleen hypoplasia J:148955
thymus hypoplasia J:148955
Kat6atm1Avo/Kat6a+
(involves: 129 * BALB/c * FVB/N)
small thymus J:188772
Kat6atm1Avo/Kat6atm1Avo
(involves: 129/Sv * BALB/c * FVB/N)
abnormal thymus development J:108453
absent spleen J:108453
athymia J:188772
decreased double-negative T cell number J:108453
small thymus J:108453, J:188772
thymus hypoplasia J:108453
Kat6atm1Iki/Kat6atm1Iki
(Not Specified)
abnormal myelopoiesis J:108699
decreased B cell number J:108699
Kat6atm2.2Avo/Kat6a+
Tbx1tm1Bld/Tbx1+

(involves: 129S7/SvEvBrd * C57BL/6)
small thymus J:188772
Kat8em1(IMPC)Mbp/Kat8+
(C57BL/6N-Kat8em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Kat14tm1a(KOMP)Wtsi/Kat14tm1a(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
decreased susceptibility to bacterial infection J:213427
Katnal1em1(IMPC)Tcp/Katnal1+
(C57BL/6NCrl-Katnal1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Katnal1em1(IMPC)Tcp/Katnal1em1(IMPC)Tcp
(C57BL/6NCrl-Katnal1em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Katnal2em1(IMPC)Tcp/Katnal2em1(IMPC)Tcp
(C57BL/6N-Katnal2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased monocyte cell number J:211773
small spleen J:211773
Kbtbd3em1(IMPC)Ccpcz/Kbtbd3em1(IMPC)Ccpcz
(C57BL/6NCrl-Kbtbd3em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased neutrophil cell number J:211773
Kbtbd11em1(IMPC)Wtsi/Kbtbd11em1(IMPC)Wtsi
(C57BL/6N-Kbtbd11em1(IMPC)Wtsi/Wtsi)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Kcna1mceph/Kcna1mceph
(BALB/cByJ-Kcna1mceph/J)
ear inflammation J:119491
eye inflammation J:119491
Kcna1tm1Tem/Kcna1tm1Tem
(involves: 129S7/SvEvBrd * BALB/cByJ * C3HeB/FeJ)
ear inflammation J:119491
eye inflammation J:119491
Kcna2em1(IMPC)H/Kcna2+
(C57BL/6NTac-Kcna2em1(IMPC)H/H)
increased neutrophil cell number J:211773
Kcna5tm1Hket/Kcna5tm1Hket
(involves: 129S6/SvEvTac * 129S7/SvEvBrd)
abnormal microglial cell morphology J:116545
Kcna10em3(IMPC)Mbp/Kcna10+
(C57BL/6N-Kcna10em3(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Kcnab2em1(IMPC)Mbp/Kcnab2em1(IMPC)Mbp
(C57BL/6NCrl-Kcnab2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Kcnc1em4(IMPC)H/Kcnc1em4(IMPC)H
(C57BL/6NTac-Kcnc1em4(IMPC)H/H)
increased neutrophil cell number J:211773
Kcne1tm1b(EUCOMM)Hmgu/Kcne1tm1b(EUCOMM)Hmgu
(C57BL/6N-Kcne1tm1b(EUCOMM)Hmgu/Ics)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Kcne2tm1a(EUCOMM)Wtsi/Kcne2tm1a(EUCOMM)Wtsi
(C57BL/6N-Kcne2tm1a(EUCOMM)Wtsi)
decreased spleen iron level J:230226
stomach inflammation J:230226
Kcne3tm1Gwab/Kcne3tm1Gwab
(involves: C57BL/6)
increased inflammatory response J:210381
Kcng3em1(IMPC)Mbp/Kcng3em1(IMPC)Mbp
(C57BL/6NCrl-Kcng3em1(IMPC)Mbp/MbpMmucd)
increased monocyte cell number J:211773
Kcnh8em1(IMPC)Mbp/Kcnh8em1(IMPC)Mbp
(C57BL/6N-Kcnh8em1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Kcnip1em1(IMPC)H/Kcnip1em1(IMPC)H
(C57BL/6N-Kcnip1em1(IMPC)H/H)
increased eosinophil cell number J:211773
Kcnj8gnite/Kcnj8gnite
(involves: C57BL/6J)
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:126658, J:105543
Kcnj8mydy/Kcnj8mydy
(involves: C57BL/6J)
increased susceptibility to endotoxin shock J:126658
increased susceptibility to Herpesvirales infection J:126658
Kcnj8slmbr/Kcnj8slmbr
(involves: C57BL/6J)
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:126658, J:105543
Kcnj8sltr/Kcnj8sltr
(involves: C57BL/6J)
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:126658, J:105543
increased susceptibility to Riboviria infection J:105543
Kcnj8sos/Kcnj8sos
(C57BL/6J-Kcnj8sos)
increased susceptibility to endotoxin shock J:149353
Kcnj9tm1b(EUCOMM)Hmgu/Kcnj9tm1b(EUCOMM)Hmgu
(C57BL/6N-Kcnj9tm1b(EUCOMM)Hmgu/H)
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Kcnj10tm1b(KOMP)Wtsi/Kcnj10+
(C57BL/6N-Kcnj10tm1b(KOMP)Wtsi/H)
decreased basophil cell number J:211773
Kcnk13em1(IMPC)H/Kcnk13em1(IMPC)H
(involves: C57BL/6NTac)
abnormal microglial cell morphology J:256020
abnormal microglial cell physiology J:256020
Kcnk13em1(IMPC)H/Kcnk13em1(IMPC)H
(C57BL/6N-Kcnk13em1(IMPC)H/H)
increased basophil cell number J:211773
increased monocyte cell number J:211773
Kcnma1em1(IMPC)H/Kcnma1em1(IMPC)H
(C57BL/6N-Kcnma1em1(IMPC)H/H)
decreased spleen weight J:211773
Kcnmb4em1(IMPC)Mbp/Kcnmb4em1(IMPC)Mbp
(C57BL/6N-Kcnmb4em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Kcnn4em1(IMPC)Ccpcz/Kcnn4em1(IMPC)Ccpcz
(C57BL/6NCrl-Kcnn4em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased spleen weight J:211773
small thymus J:211773
Kcnn4tm1Jemn/Kcnn4tm1Jemn
(involves: 129S1/Sv * C57BL/6J)
abnormal T cell physiology J:94478
Kcnn4tm1Rklr/Kcnn4tm1Rklr
(involves: 129S/SvEv * C57BL/6)
enlarged spleen J:148910
increased spleen iron level J:148910
increased spleen weight J:148910
Kcnt1em1(IMPC)Mbp/Kcnt1em1(IMPC)Mbp
(C57BL/6N-Kcnt1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Kcnt2em1(IMPC)Mbp/Kcnt2em1(IMPC)Mbp
(C57BL/6N-Kcnt2em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Kctd1em1(IMPC)J/Kctd1em1(IMPC)J
(C57BL/6NJ-Kctd1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Kctd9em1Beij/Kctd9em1Beij
(BALB/c-Kctd9em1Beij)
abnormal immature NK cell morphology J:281803
abnormal NK cell differentiation J:281803
abnormal NK cell physiology J:281803
decreased mature NK cell number J:281803
decreased susceptibility to Coronaviridae infection J:281803
decreased susceptibility to Coronaviridae infection induced morbidity/mortality J:281803
impaired natural killer cell mediated cytotoxicity J:281803
increased immature NK cell number J:281803
increased NK cell number J:281803
Kdelr1em1Btlr/Kdelr1em1Btlr
(involves: C57BL/6J * C57BL/6JJcl)
decreased lymphocyte cell number J:224970
Kdelr1em1Btlr/Kdelr1em1Btlr
Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr/0

(C57BL/6J-Kdelr1em1Btlr Tg(Gt(ROSA)26Sor-Kdelr1)#Btlr)
abnormal lymphocyte morphology J:224970
Kdelr1m1Btlr/Kdelr1m1Btlr
(C57BL/6J-Kdelr1m1Btlr)
abnormal lymphocyte morphology J:224970
abnormal response to infection J:224970
abnormal T cell differentiation J:224970
absent NK T cells J:224970
decreased B cell number J:224970
decreased CD4-positive, alpha-beta T cell number J:224970, J:158794
decreased CD8-positive, alpha-beta T cell number J:224970, J:158794
decreased follicular B cell number J:224970
decreased lymphocyte cell number J:224970
decreased transitional stage T1 B cell number J:224970
decreased transitional stage T2 B cell number J:224970
immune system phenotype J:224970
increased marginal zone B cell number J:224970
increased susceptibility to Riboviria infection J:224970
thymus hypoplasia J:158794
Kdm1atm1(NCOM)Mfgc/Kdm1a+
(C57BL/6N-Kdm1atm1(NCOM)Mfgc/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
small spleen J:211773
Kdm1atm1.1Sho/Kdm1atm1.1Sho
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca)
decreased leukocyte cell number J:201572
Kdm1atm1.1Sho/Kdm1atm1.1Sho
Tg(Mx1-cre)1Cgn/?

(involves: 129 * C57BL/6 * CBA/Ca)
decreased granulocyte number J:201572
decreased neutrophil cell number J:201572
Kdm3aem1(IMPC)Mbp/Kdm3aem1(IMPC)Mbp
(C57BL/6N-Kdm3aem1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Kdm4ctm1a(KOMP)Wtsi/Kdm4c+
(C57BL/6N-Kdm4ctm1a(KOMP)Wtsi/Wtsi)
increased B cell number J:165965
Kdm5atm1.1Kael/Kdm5atm1.1Kael
(involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL)
increased neutrophil cell number J:137185
Kdm6atm1.1Afst/Kdm6atm1.1Afst
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6NTac)
abnormal granulocyte morphology J:196401
decreased leukocyte cell number J:196401
enlarged spleen J:196401
increased B cell number J:196401
increased spleen weight J:196401
Kdm6atm1Cdcn/Y
Tg(CAG-cre/Esr1*)5Amc/0

(involves: C57BL/6J * CBA)
enlarged spleen J:263565
increased granulocyte number J:263565
increased monocyte cell number J:263565
increased neutrophil cell number J:263565
Kdm6atm1Cdcn/Y
Tg(CAG-cre/Esr1*)5Amc/0
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129S2/SvPas * C57BL/6J * CBA * FVB/N)
enlarged spleen J:263565
increased monocyte cell number J:263565
increased neutrophil cell number J:263565
Kdm6atm1Cdcn/Kdm6atm1Cdcn
Tg(CAG-cre/Esr1*)5Amc/0

(involves: C57BL/6J * CBA)
enlarged spleen J:263565
increased granulocyte number J:263565
increased monocyte cell number J:263565
increased neutrophil cell number J:263565
Kdm6btm1Aki/Kdm6btm1Aki
(involves: 129X1/SvJ * C57BL/6)
abnormal response to infection J:164690
impaired eosinophil recruitment J:164690
Kdm8tm1a(EUCOMM)Wtsi/Kdm8+
(C57BL/6N-Kdm8tm1a(EUCOMM)Wtsi/Ics)
increased B cell number J:165965
Kdrtm1.1Jamb/Kdrtm1.1Jamb
(involves: 129S1/Sv * 129X1/SvJ * ICR)
abnormal lymphangiogenesis J:154336
lymphatic vessel hyperplasia J:154336
Kdrtm1.1Jamb/Kdrtm1.1Jamb
Tg(KRT14-cre)1Efu/0

(involves: 129S1/Sv * 129X1/SvJ * ICR)
lymphatic vessel hyperplasia J:154336
Kdrtm1.1Jamb/Kdrtm1.1Jamb
Tg(Pax6-cre,GFP)1Pgr/0

(involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR)
abnormal lymphatic vessel morphology J:154336
lymphatic vessel hyperplasia J:154336
Kdrtm1Jrt/Kdr+
Tmem204tm1.1Ali/Tmem204tm1.1Ali

(involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6)
abnormal lymphatic vessel smooth muscle morphology J:159519
enlarged lymphatic vessel J:159519
Kdrtm1Ykub/Kdrtm1Ykub
(Not Specified)
enlarged lymphatic vessel J:217533
lymphatic vessel hyperplasia J:217533
Keratm1Cyl/Keratm1Cyl
(involves: 129S6/SvEvTac)
abnormal inflammatory response J:128992
decreased neutrophil cell number J:128992
Khdrbs1tm1Rchd/Khdrbs1tm1Rchd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal bone marrow development J:115775
Khsrptm1.1Cyc/Khsrptm1.1Cyc
(B6.Cg-Khsrptm1.1Cyc)
decreased susceptibility to Herpesvirales infection J:175084
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:175084
increased interferon-beta secretion J:175084
Kif1cLtxs1-DBA/2NCr/Kif1cLtxs1-DBA/2NCr
(involves: BALB/cAnPt * DBA/2NCr)
decreased susceptibility to infection J:103336
Kif1cLtxs1-DBA/2NCr/Kif1cLtxs1-DBA/2NCr
Ltxs2DBA/2NCr/Ltxs2DBA/2NCr
Ltxs3DBA/2NCr/Ltxs3DBA/2NCr

(involves: BALB/cAnPt * DBA/2NCr)
decreased susceptibility to infection J:103336
Kif1cLtxs1/Kif1c+
(involves: C3H/HeJ * C57BL/6J)
increased susceptibility to bacterial infection J:49726
Kif1cLtxs1/Kif1cLtxs1
(involves: C3H/HeJ * C57BL/6J)
increased susceptibility to bacterial infection J:49726
Kif1cOrch3-BALB/cByJ/Kif1cOrch3-BALB/cByJ
(involves: BALB/cByJ * DBA/2)
testis inflammation J:35331
Kif1cOrch3-BALB/cByJ/Kif1cOrch3-DBA/2J
(involves: BALB/cByJ * DBA/2)
decreased inflammatory response J:35331
Kif1cOrch3-DBA/2J/Kif1cOrch3-DBA/2J
(involves: BALB/cByJ * DBA/2)
decreased inflammatory response J:35331
Kif5ctm1dIcs/Kif5c+
(C57BL/6N-Kif5ctm1dIcs/Ics)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Kif9em1(IMPC)Mbp/Kif9em1(IMPC)Mbp
(C57BL/6N-Kif9em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Kif13aem1(IMPC)Mbp/Kif13aem1(IMPC)Mbp
(C57BL/6N-Kif13aem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Kif13btm1b(EUCOMM)Wtsi/Kif13btm1b(EUCOMM)Wtsi
(C57BL/6N-Kif13btm1b(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Kif15em1Lium/Kif15em1Lium
(C57BL/6-Kif15em1Lium)
decreased spleen white pulp amount J:336767
increased CD8-positive, alpha-beta T cell number J:336767
increased spleen red pulp amount J:336767
increased spleen weight J:336767
intermingled spleen red and white pulp J:336767
Kif16bem1(IMPC)Ccpcz/Kif16bem1(IMPC)Ccpcz
(C57BL/6NCrl-Kif16bem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Kif27Gt(OST441915)Lex/Kif27Gt(OST441915)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased susceptibility to otitis media J:185566
maxillary sinus inflammation J:185566
Kifbptm1a(KOMP)Wtsi/Kifbptm1a(KOMP)Wtsi
(C57BL/6N-Kifbptm1a(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
(C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd)
increased spleen weight J:211773
Kiss1rtm1.1Lex/Kiss1r+
(involves: 129S4/SvJae)
decreased eosinophil cell number J:181650
decreased lymphocyte cell number J:181650
Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
(involves: 129S4/SvJae)
decreased basophil cell number J:181650
decreased lymphocyte cell number J:181650
decreased monocyte cell number J:181650
decreased neutrophil cell number J:181650
increased spleen weight J:181650
increased thymus weight J:181650
Kiss1rtm1Gstn/Kiss1rtm1Gstn
(involves: 129P2/OlaHsd)
increased thymus weight J:102113
Kittm1.1Bsm/Kittm1.1Bsm
(involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N)
abnormal mast cell physiology J:61141
decreased mast cell number J:61141
Kittm1.1Bsm/Kittm1.1Bsm
(B6.129S1-Kittm1.1Bsm)
immune system phenotype J:90485
Kittm1Ber/Kittm1Ber
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased mast cell number J:89602
immune system phenotype J:89602
Kittm1Bpr/Kittm1Bpr
(either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6))
decreased mast cell number J:100778
Kittm1Bsm/Kittm1Bsm
(involves: 129S1/Sv * C57BL/6J)
decreased mast cell number J:61141
Kittm2Ber/Kittm2Ber
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased mast cell number J:89602
immune system phenotype J:89602
Kittm2Bsm/Kit+
(involves: 129X1/SvJ * C57BL/6J)
increased mast cell degranulation J:83616
increased mast cell number J:83616
Kittm3.1Bsm/Kittm3.1Bsm
(involves: 129S1/Sv * C57BL/6)
abnormal B cell differentiation J:90485
abnormal mast cell physiology J:90485
abnormal T cell differentiation J:90485
decreased B cell number J:90485
decreased mast cell number J:90485
immune system phenotype J:90485
Kittm3.1Bsm/Kittm3.1Bsm
(B6.129S1-Kittm3.1Bsm)
spleen hypoplasia J:146561
Kittm3Ber/Kittm3Ber
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
arrested B cell differentiation J:89602
decreased mast cell number J:89602
enlarged spleen J:89602
increased B cell number J:89602
spleen hyperplasia J:89602
Kittm4.1Bsm/Kit+
(involves: 129S1/Sv * C57BL/6J * FVB/N)
enlarged spleen J:188434
increased mast cell number J:188434
spleen hyperplasia J:188434
KitW-37J/Kit+
(involves: C57BL/6 * C57BL/6J)
decreased mast cell number J:27513
KitW-37J/KitW
(involves: C57BL/6 * C57BL/6J * WB)
abnormal mast cell physiology J:27513
decreased mast cell number J:27513
KitW-42J/Kit+
(involves: C57BL/6 * C57BL/6J * WB)
decreased mast cell number J:27513
KitW-42J/KitW
(involves: C57BL/6 * C57BL/6J * WB)
abnormal mast cell physiology J:27513
decreased mast cell number J:27513
KitW-Btlr/KitW-Btlr
(C57BL/6J-KitW-Btlr)
decreased mast cell number J:133270
KitW-f/KitW-f
(involves: C3H/HePas)
decreased mast cell number J:27513
KitW-Jic/Kit+
(involves: C57BL/6)
decreased mast cell number J:27513
KitW-Jic/KitW
(involves: C57BL/6 * WB)
abnormal mast cell physiology J:27513
decreased mast cell number J:27513
KitW-n/KitW-n
(Not Specified)
decreased mast cell number J:12107
KitW-n/KitW
(involves: WB)
abnormal mast cell physiology J:27513
decreased mast cell number J:27513
KitW-sh/KitW-sh
(involves: 101/H * C3H/HeH)
decreased mast cell degranulation J:157470
decreased mast cell number J:145444
increased susceptibility to parasitic infection J:163761
KitW-sh/KitW-sh
(involves: C57BL/6J)
decreased susceptibility to type I hypersensitivity reaction J:197334
KitW-sh/KitW-sh
(B6.Cg-KitW-sh/HNihrJaeBsmGlliJ)
decreased susceptibility to type I hypersensitivity reaction J:275367
KitW-sh/KitW-sh
Lyntm1Ard/Lyntm1Ard

(involves: 101 * 129P2/OlaHsd * C3H/HeH)
abnormal circulating complement protein level J:161523
decreased B cell number J:161523
glomerulonephritis J:161523
increased anti-double stranded DNA antibody level J:161523
increased anti-nuclear antigen antibody level J:161523
increased basophil cell number J:161523
increased IgA level J:161523
increased IgE level J:161523
increased IgG2b level J:161523
increased IgM level J:161523
KitW-v/Kit+
(involves: C57BL * C57BL/6)
decreased mast cell number J:27513
KitW-vkd/KitW-vkd
(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * WB)
abnormal B cell differentiation J:79128
abnormal T cell differentiation J:79128
decreased B cell number J:79128
decreased thymocyte number J:79128
KitW/Kit+
Tg(PGK1-KITLG*220)441Daw/0

(involves: C3H/HeJ)
decreased mast cell number J:32600
KitW/KitW-v
(involves: C57BL/6 * WB)
abnormal response to transplant J:6084
KitW/KitW-v
((WB/ReJ x C57BL/6J-KitW-v/J)F1-KitW/KitW-v/J)
abnormal interferon level J:131785
abnormal interleukin level J:131785
decreased inflammatory response J:131785
immune system phenotype J:125656
impaired neutrophil recruitment J:123463
kidney inflammation J:113500
KitW/KitW-v
(involves: C57BL/6)
decreased basophil cell number J:178942
decreased mast cell number J:178942
immune system phenotype J:178942
KitW/KitW-v
((WB KitW x B6.Cg-KitW-v)F1)
decreased susceptibility to induced arthritis J:178942
decreased susceptibility to type I hypersensitivity reaction J:197334
KitW/KitW
Tg(PDGFB-EPO)321Zbz/?

(involves: C3H * C57BL/6)
abnormal B cell differentiation J:79128
abnormal T cell differentiation J:79128
decreased B cell number J:79128
decreased thymocyte number J:79128
KitWads/KitWads
(C57BL/6J-KitWads)
decreased mast cell number J:96391
KitlSl-con/KitlSl-con
(either: (involves: C3H/HeJ) or (involves: C3H/HeN))
increased mast cell number J:23593
KitlSl-d/Kitl+
(either: (involves: C57BL/6 * DBA/2J) or (involves: C3H * C57BL/6 * DBA/2J * WC))
decreased mast cell number J:6084
KitlSl/Kitl+
(either: (involves: C3H * WC) or (involves: C3H * C57BL/6 * DBA/2J * WC))
decreased mast cell number J:6084
KitlSl/Kitl+
Tg(PGK1-KITLG*220)441Daw/0

(involves: C3H)
decreased mast cell number J:32600
KitlSl/KitlSl-d
(involves: C57BL/6 * WC)
dermatitis J:5758
stomach inflammation J:2777
thymus atrophy J:5758
KitlSl/KitlSl-d
(involves: C3H * C57BL/6 * DBA/2J * WC)
abnormal response to transplant J:6084
decreased mast cell number J:6084
KitlSl/KitlSl-d
((WC/ReJ KitlSl x B6.D2-KitlSl-d/J)F1-KitlSl/KitlSl-d/J)
abnormal osteoclast morphology J:111273
Kitltm1.1Sjm/Kitltm2.1Sjm
Leprtm2(cre)Rck/Lepr+

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/Ka * SJL)
enlarged spleen J:180431
spleen hyperplasia J:180431
Kitltm1.1Sjm/Kitltm2.1Sjm
Leprtm2(cre)Rck/Lepr+
Tg(Tek-cre)12Flv/0

(involves: 129S6/SvEvTac * C3H * C57BL/6 * C57BL/Ka * SJL)
spleen hyperplasia J:180431
Kitltm1Pbes/Kitltm1Pbes
(involves: 129S1/Sv * C57BL/6J)
decreased mast cell number J:50150
Kitltm2.1Pbes/Kitltm2.1Pbes
(involves: 129S1/Sv * C57BL/6J * FVB/N)
increased mast cell number J:157170
Kitltm3.1Pbes/Kitltm3.1Pbes
(involves: 129S1/Sv * C57BL/6J * FVB/N)
decreased double-negative T cell number J:157170
decreased double-positive T cell number J:157170
decreased mast cell number J:157170
decreased T cell number J:157170
decreased thymocyte number J:157170
Klecalc1/Klecalc1
(involves: C3H/HeH * C57BL/6J)
lung inflammation J:229255
Klkl/Klkl
(either: C.Cg-Klkl or (involves: C3H/HeJ * C57BL/6J))
abnormal leukocyte cell number J:44109
decreased osteoclast cell number J:44109
thymus atrophy J:44109
Klkl/Klkl
(involves: C3H/HeJ * C57BL/6J)
decreased B cell number J:80503
decreased osteoclast cell number J:80503
Klkl/Klkl
(involves: C3H/J * C57BL/6J)
abnormal osteoclast morphology J:56666
Klkl/Klkl
Tnfrsf11btm1Khs/Tnfrsf11b+

(involves: 129P2/OlaHsd * C3H * C57BL/6)
decreased B cell number J:80503
Klm1Anu/Klm1Anu
(C57BL/6NCrlAnu-Klm1Anu)
abnormal spleen morphology J:104190
small spleen J:104190
Klf1Nan/Klf1+
(either: B6.Cg-Klf1Nan or WB.Cg-Klf1Nan)
increased spleen weight J:162530
Klf1Nan/Klf1+
(involves: 101/H * C3H/HeH * PT)
enlarged spleen J:13933
increased spleen iron level J:13933
Klf2tm1Ling/Klf2tm1Ling
(involves: 129P2/OlaHsd * C57BL/6J)
immune system phenotype J:51402
Klf2tm1Mlkn/Klf2tm1Mlkn
Tg(VAV1-cre)1Graf/0

(Not Specified)
absent T cells J:127228
Klf2tm2Ling/Klf2tm2Ling
Lyz2tm1(cre)Ifo/0

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
decreased Ly6C low monocyte number J:239509
Klf2tm2Ling/Klf2tm2Ling
Tg(Cd4-cre)1Cwi/?

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal T cell differentiation J:151604
decreased T cell number J:151604
increased IgE level J:151604
increased IgG1 level J:151604
increased interleukin-4 secretion J:151604
increased single-positive T cell number J:151604
Klf3Gt(CH0516)Wtsi/Klf3Gt(CH0516)Wtsi
(involves: 129P2/OlaHsd * C57BL/6)
increased leukocyte cell number J:206507
increased spleen weight J:206507
Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi
(involves: 129P2/OlaHsd * C57BL/6)
increased leukocyte cell number J:206507
increased spleen weight J:206507
Klf3m1Cmhd/Klf3+
(involves: C3H/HeJ * C57BL/6J)
increased spleen weight J:206507
Klf4tm1Khk/Klf4tm1Khk
Lyz2tm1(cre)Ifo/0

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
decreased Ly6C low monocyte number J:239509
Klf4tm1Khk/Klf4tm1Khk
Tg(Pax6-cre,GFP)1Pgr/0

(involves: 129S6/SvEvTac * FVB/N)
blepharitis J:117671
Klf5Gt(XB751)Byg/Klf5+
(B6.129P2-Klf5Gt(XB751)Byg)
abnormal response to infection J:136125
Klf5M1Btlr/Klf5M1Btlr
(C57BL/6J-Klf5M1Btlr)
increased susceptibility to induced colitis J:265229
Klf5tm1Jaw/Klf5tm1Jaw
Tg(Pax6-cre,GFP)1Pgr/0

(involves: FVB)
lacrimal gland inflammation J:175263
Klf13tm1Coll/Klf13tm1Coll
(involves: 129S/SvEv)
decreased leukocyte cell number J:136545
decreased lymphocyte cell number J:136545
enlarged spleen J:136545
spleen hyperplasia J:136545
Klf13tm1Kren/Klf13tm1Kren
(B6.129-Klf13tm1Kren)
abnormal immune system cell morphology J:145839
abnormal immune system organ morphology J:145839
abnormal spleen morphology J:145839
abnormal T cell number J:145839
decreased splenocyte apoptosis J:145839
decreased thymocyte apoptosis J:145839
decreased thymocyte number J:145839
increased double-positive T cell number J:145839
increased splenocyte number J:145839
increased thymocyte number J:145839
spleen hyperplasia J:145839
thymus hyperplasia J:145839
Klf15tm1Jain/Klf15tm1Jain
(involves: 129X1/SvJ)
blood vessel inflammation J:203920
increased macrophage cell number J:203920
Klf16em1(IMPC)J/Klf16+
(C57BL/6NJ-Klf16em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Klhdc2tm1b(EUCOMM)Hmgu/Klhdc2+
(C57BL/6N-Klhdc2tm1b(EUCOMM)Hmgu/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
small thymus J:211773
Klhdc7bem1(IMPC)H/Klhdc7bem1(IMPC)H
(C57BL/6N-Klhdc7bem1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Klhdc10tm1Hijo/Klhdc10tm1Hijo
(B6J.B6N-Klhdc10tm1Hijo)
decreased circulating interleukin-6 level J:251158
decreased inflammatory response J:251158
decreased interleukin-6 secretion J:251158
Klhl1em1(IMPC)Ccpcz/Klhl1em1(IMPC)Ccpcz
(C57BL/6N-Klhl1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
small spleen J:211773
Klhl6m1Anu/Klhl6m1Anu
(C57BL/6JAnu-Klhl6m1Anu)
decreased B cell number J:104190
decreased mature B cell number J:104190
increased immature B cell number J:104190
Klhl6m1Btlr/Klhl6m1Btlr
(C57BL/6J-Klhl6m1Btlr)
decreased B cell number J:265167
decreased central memory CD4-positive, alpha-beta T cell number J:265167
increased B-1b cell number J:265167
increased CD4-positive, alpha-beta T cell number J:265167
increased single-positive T cell number J:265167
increased T cell number J:265167
Klhl6m2Btlr/Klhl6m2Btlr
(C57BL/6J-Klhl6m2Btlr)
decreased CD8-positive, alpha-beta T cell number J:265168
increased CD4-positive, alpha-beta T cell number J:265168
increased single-positive T cell number J:265168
increased T cell number J:265168
Klhl6M3Btlr/Klhl6M3Btlr
(C57BL/6J-Klhl6M3Btlr)
increased alpha-beta T cell number J:267699
increased B-1a cell number J:267699
increased CD4-positive, alpha-beta T cell number J:267699
increased CD8-positive, alpha-beta T cell number J:267699
Klhl6m4Btlr/Klhl6m4Btlr
(C57BL/6J-Klhl6m4Btlr)
increased B-1 B cell number J:272394
Klhl6M5Btlr/Klhl6M5Btlr
(C57BL/6J-Klhl6M5Btlr)
increased B-1 B cell number J:272395
Klhl6m6Btlr/Klhl6m6Btlr
(C57BL/6J-Klhl6m6Btlr)
increased alpha-beta T cell number J:272396
increased CD4-positive, alpha-beta T cell number J:272396
Klhl6M7Btlr/Klhl6M7Btlr
(C57BL/6J-Klhl6M7Btlr)
abnormal B cell differentiation J:272397
Klhl6M8Btlr/Klhl6M8Btlr
(C57BL/6J-Klhl6M8Btlr)
decreased B cell number J:274963
increased CD4-positive, alpha-beta T cell number J:274963
increased T cell number J:274963
Klhl6tm1Sato/Klhl6tm1Sato
(either: (involves: 129T2/SvEms) or (involves: BALB/c) or (involves: CD-1))
abnormal adaptive immunity J:101363
abnormal B cell differentiation J:101363
abnormal lymph node germinal center morphology J:101363
abnormal spleen morphology J:101363
decreased B cell number J:101363
decreased follicular B cell number J:101363
decreased spleen weight J:101363
spleen hypoplasia J:101363
Klhl14tm1.1Jyw/Klhl14+
(involves: C57BL/6)
decreased B-1a cell number J:263511
immune system phenotype J:263511
increased B-1b cell number J:263511
Klhl22em1Cya/Klhl22em1Cya
(C57BL/6N-Klhl22em1Cya/Cya)
decreased interferon-gamma secretion J:297538
decreased tumor necrosis factor secretion J:297538
Klhl29tm1b(EUCOMM)Hmgu/Klhl29+
(C57BL/6N-Klhl29tm1b(EUCOMM)Hmgu/Ics)
increased large unstained cell number J:211773
Klk4tm1.1(KOMP)Vlcg/Klk4tm1.1(KOMP)Vlcg
(C57BL/6N-Klk4tm1.1(KOMP)Vlcg/Ucd)
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Klk5em1Mer/Klk5em1Mer
(BALB/c-Klk5em1Mer)
abnormal acute inflammation J:344772
Klk6tm1Gsot/Klk6+
(involves: C57BL/6)
decreased inflammatory response J:270051
decreased susceptibility to chemically induced skin inflammation J:270051
Klk6tm1Gsot/Klk6tm1Gsot
(involves: C57BL/6)
abnormal cytokine level J:270051
decreased inflammatory response J:270051
decreased susceptibility to chemically induced skin inflammation J:270051
Klk6tm1Gsot/Klk6tm1Gsot
Spink5tm1Drh/Spink5tm1Drh

(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine level J:289877
decreased inflammatory response J:289877
Klk8em1(IMPC)Ccpcz/Klk8em1(IMPC)Ccpcz
(C57BL/6N-Klk8em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
Klk11em1(IMPC)Ccpcz/Klk11em1(IMPC)Ccpcz
(C57BL/6N-Klk11em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Klra1tm1.1Wyok/Klra1tm1.1Wyok
(involves: BALB/cJ * C57BL/6NTac)
abnormal natural killer cell mediated cytotoxicity J:252851
Klra5tm1.1Cgbr/Klra5tm1.1Cgbr
(involves: C57BL/6 * SJL)
immune system phenotype J:169142
Klra5tm1.2Glec/Klra5tm1.2Glec
(involves: C57BL/6)
immune system phenotype J:201231
Klra8Cmv1-del/Klra8Cmv1-r
((BXD8/TyJ x C57BL/6)F1)
decreased susceptibility to Herpesvirales infection J:79093
Klra8Cmv1-del/Klra8Cmv1-s
((BXD8/TyJ x BALB/c)F1)
increased susceptibility to Herpesvirales infection J:79093
Klra8Cmv1-del/Klra8Cmv1-s
((BXD8/TyJ x DBA/2)F1)
increased susceptibility to Herpesvirales infection J:79093
Klra8Cmv1-r/Klra8Cmv1-r
(C.B6-Klra8Cmv1-r)
decreased IgG1 level J:97203
decreased IgG2a level J:97203
decreased IgG2b level J:97203
decreased IgG3 level J:97203
decreased IgG level J:97203
decreased interleukin-4 secretion J:97203
decreased susceptibility to Herpesvirales infection J:22486, J:79093
increased circulating interferon-gamma level J:97203
increased IgM level J:97203
increased susceptibility to infection induced morbidity/mortality J:97203
increased susceptibility to parasitic infection J:97203
Klra15tm1.1Apma/Klra15tm1.1Apma
(B6.129-Klra15tm1.1Apma)
impaired natural killer cell mediated cytotoxicity J:189106
Klra17tm1.1Apma/Klra17tm1.1Apma
(involves: 129S1/Sv * 129X1/SvJ)
abnormal plasmacytoid dendritic cell physiology J:152288
abnormal response to infection J:152288
decreased circulating interferon-alpha level J:152288
decreased circulating interleukin-12 level J:152288
decreased interferon-alpha secretion J:152288
decreased interleukin-12 secretion J:152288
increased plasmacytoid dendritic cell number J:152288
increased susceptibility to Herpesvirales infection J:152288
Klrb1tm1b(EUCOMM)Wtsi/Klrb1tm1b(EUCOMM)Wtsi
(C57BL/6N-Klrb1tm1b(EUCOMM)Wtsi/Ieg)
decreased leukocyte cell number J:211773
increased follicular B cell number J:211773
Klrb1btm1.1Apma/Klrb1btm1.1Apma
(B6.Cg-Klrb1btm1.1Apma)
abnormal NK cell physiology J:222057
Klrc1tm1Mmka/Klrc1tm1Mmka
(B6.129-Klrc1tm1Mmka)
decreased CD8-positive, alpha-beta T cell number J:222503
decreased tumor necrosis factor secretion J:222503
immune system phenotype J:222503
increased interferon-gamma secretion J:222503
increased interleukin-2 secretion J:222503
increased susceptibility to Adenoviridae infection J:222503
increased susceptibility to Orthomyxoviridae infection J:222503
increased tumor necrosis factor secretion J:222503
liver inflammation J:222503
lung inflammation J:222503
Klrd1tm1.1Lll/Klrd1tm1.1Lll
(B6.129X1-Klrd1tm1.1Lll)
immune system phenotype J:167730
Klre1tm1Tgi/Klre1tm1Tgi
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
impaired natural killer cell mediated cytotoxicity J:92262
Klrg2em1(IMPC)H/Klrg2em1(IMPC)H
(C57BL/6NTac-Klrg2em1(IMPC)H/H)
enlarged spleen J:211773
Klrk1em1(IMPC)Mbp/Klrk1em1(IMPC)Mbp
(C57BL/6NCrl-Klrk1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Klrk1tm1.1Bpol/Klrk1tm1.1Bpol
(C57BL/6-Klrk1tm1.1Bpol)
abnormal NK cell differentiation J:151878
abnormal NK cell physiology J:151878
decreased B cell number J:151878
decreased susceptibility to Herpesvirales infection J:151878
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:151878
decreased T cell number J:151878
impaired natural killer cell mediated cytotoxicity J:151878
increased interferon-gamma secretion J:151878
spleen hypoplasia J:151878
Klrk1tm1Dhr/Klrk1tm1Dhr
(involves: C57BL/6 * CD-1)
impaired natural killer cell mediated cytotoxicity J:134509
Klrk1tm1Dhr/Klrk1tm1Dhr
(B6.Cg-Klrk1tm1Dhr/J)
increased natural killer cell mediated cytotoxicity J:221188
Klrk1tm2.1Bpol/Klrk1tm2.1Bpol
(Not Specified)
abnormal NK cell differentiation J:215590
decreased susceptibility to Herpesvirales infection J:215590
Kmt2atm1(AFF1)Ksy/Kmt2a+
(involves: 129S1/Sv * C57BL/6 * FVB)
abnormal lymphocyte morphology J:110241
enlarged spleen J:110241
increased leukocyte cell number J:110241
increased monocyte cell number J:110241
increased neutrophil cell number J:110241
increased pro-B cell number J:110241
lymphoid hyperplasia J:110241
myeloid hyperplasia J:110241
Kmt2atm1(MLL1/ERT)Divo/?
(involves: 129S4/SvJae * C57BL/6)
enlarged spleen J:189329
myeloid hyperplasia J:189329
Kmt2atm1.1(Sh3gl1)Lcc/Kmt2a+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
enlarged lymph nodes J:205605
enlarged spleen J:205605
myeloid hyperplasia J:205605
Kmt2atm1.1Erns/Kmt2atm1.1Erns
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL)
immune system phenotype J:147265
Kmt2atm1.1Erns/Kmt2atm1.1Erns
Tg(Lck-cre)1Cwi/0

(involves: 129S2/SvPas * C57BL/6 * SJL)
immune system phenotype J:147265
Kmt2atm1Brad/Kmt2atm1Brad
Commd10Tg(Vav1-icre)A2Kio/?

(involves: 129S4/SvJae * C57BL/6 * C57BL/10 * CBA/Ca)
decreased pre-B cell number J:149811
Kmt2atm1Clgr/Kmt2a+
(B6.129-Kmt2atm1Clgr)
abnormal myelopoiesis J:115001
Kmt2atm1Sjk/Kmt2a+
(involves: 129S2/SvPas * C3H * C57BL/6)
decreased B cell number J:29958
Kmt2atm1Thr/Kmt2a+
Mllt3tm2Thr/Mllt3+
Tg(Lck-cre)1Thr/?

(involves: 129S/SvEv)
abnormal spleen red pulp morphology J:100794
abnormal spleen white pulp morphology J:100794
enlarged spleen J:100794
Kmt2atm2(MLLT3)Thr/Kmt2a+
(involves: 129P2/OlaHsd)
enlarged spleen J:56340
Kmt2atm2(MLLT3)Thr/Kmt2atm2(MLLT3)Thr
(involves: 129P2/OlaHsd * C57BL/6 * FVB)
increased leukocyte cell number J:110241
increased neutrophil cell number J:110241
increased pro-B cell number J:110241
Kmt2atm2Sjk/Kmt2a+
Tg(Mx1-cre)1Cgn/0

(involves: 129X1/SvJ * C57BL/6 * CBA)
abnormal spleen morphology J:95914
enlarged spleen J:95914
increased leukocyte cell number J:95914
increased spleen red pulp amount J:95914
myeloid hyperplasia J:95914
Kmt2dtm1.1Kaig/Kmt2d+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
increased germinal center B cell number J:228913
increased spleen germinal center size J:228913
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:228913
decreased B cell number J:228913
decreased follicular B cell number J:228913
decreased IgG1 level J:228913
decreased IgM level J:228913
decreased mature B cell number J:228913
immune system phenotype J:228913
increased B cell proliferation J:228913
increased germinal center B cell number J:228913
increased spleen germinal center number J:228913
increased spleen germinal center size J:228913
Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:228913
Kmt2etm1.1Hjf/Kmt2e+
(B6.129P2-Kmtetm1.1Hjf)
decreased thymocyte number J:145579
spleen hypoplasia J:145579
thymus hypoplasia J:145579
Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
(B6.129P2-Kmtetm1.1Hjf)
abnormal lymphopoiesis J:145579
decreased B cell number J:145579
decreased double-negative T cell number J:145579
decreased double-positive T cell number J:145579
decreased leukocyte cell number J:145579
decreased macrophage cell number J:145579
decreased pre-B cell number J:145579
decreased pro-B cell number J:145579
decreased T cell number J:145579
decreased thymocyte number J:145579
immune system phenotype J:145579
small lymph nodes J:145579
small spleen J:145579
small thymus J:145579
spleen hypoplasia J:145579
thymus hypoplasia J:145579
Kmt2etm1Apa/Kmt2etm1Apa
(129S6/SvEvTac-Kmt2etm1Apa)
abnormal granulocyte differentiation J:145445
abnormal neutrophil differentiation J:145445
abnormal neutrophil physiology J:145445
blepharitis J:145445
increased susceptibility to bacterial infection J:145445
Kmt2etm1Nik/Kmt2etm1Nik
(B6.Cg-Kmtetm1Nik)
decreased NK cell number J:145449
decreased NK T cell number J:145449
increased neutrophil cell number J:145449
Kmt5btm1Jnw/Kmt5btm1Jnw
Kmt5ctm1.1Jnw/Kmt5ctm1.1Jnw
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129/Sv * C57BL/6J * C57BL/10 * CBA/Ca)
abnormal class switch recombination J:139510
abnormal lymphopoiesis J:139510
decreased B cell number J:139510
decreased double-positive T cell number J:139510
immune system phenotype J:139510
Knl1tm1c(EUCOMM)Hmgu/Knl1tm1c(EUCOMM)Hmgu
Tg(GFAP-cre)25Mes/0

(involves: 129S4/SvJaeSor * C57BL/6N * FVB/N)
microgliosis J:278483
Knop1tm1b(EUCOMM)Wtsi/Knop1tm1b(EUCOMM)Wtsi
(C57BL/6N-Knop1tm1b(EUCOMM)Wtsi/Bay)
increased spleen weight J:211773
Kpna4tm1Bdr/Kpna4tm1Bdr
(B6.Cg-Kpna4tm1Bdr)
increased susceptibility to Orthomyxoviridae infection J:302003
Kprptm1Msug/Kprp+
(involves: C57BL/6)
increased IgE level J:286659
increased susceptibility to chemically induced skin inflammation J:286659
Kptntm1a(EUCOMM)Wtsi/Kptntm1a(EUCOMM)Wtsi
(involves: C57BL/6N)
increased susceptibility to bacterial infection J:200082
Krastm1.1Khai/Kras+
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA/J)
enlarged spleen J:276349
increased leukocyte cell number J:276349
Krastm1Mok/Kras+
Nrastm1Mok/Nras+

(involves: 129S/SvEv * C57BL/6 * DBA/2)
abnormal lymphatic vessel morphology J:159024
Krastm4.1Bbd/Kras+
(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N)
enlarged spleen J:223433
Krastm4.1Bbd/Krastm4.1Bbd
(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N)
decreased CD8-positive, alpha-beta T cell number J:223433
enlarged spleen J:223433
increased basophil cell number J:223433
increased eosinophil cell number J:223433
increased leukocyte cell number J:223433
increased neutrophil cell number J:223433
spleen vascular congestion J:223433
Krastm4Tyj/Kras+
(involves: 129S4/SvJae)
increased regulatory T cell number J:154046
Krastm4Tyj/Kras+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Tg(Flt3-cre)#Ccb/0

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6)
decreased B cell number J:247853
decreased double-negative T cell number J:247853
decreased double-positive T cell number J:247853
decreased T cell number J:247853
hepatosplenomegaly J:247853
increased dendritic cell number J:247853
increased leukocyte cell number J:247853
increased monocyte cell number J:247853
thymus atrophy J:247853
Krastm4Tyj/Kras+
Krt19tm1(cre/ERT)Ggu/Krt19+
Ptentm2Mak/Ptentm2Mak

(involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac)
lung inflammation J:254370
Krastm4Tyj/Kras+
Lrrc17tm1Nik/Lrrc17+
Srpk2tm1Nik/Srpk2+
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA)
increased leukocyte cell number J:161558
Krastm4Tyj/Kras+
Pggt1btm1Mbrg/Pggt1b+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:122107
decreased lymphocyte cell number J:122107
increased neutrophil cell number J:122107
Krastm4Tyj/Kras+
Ptentm1Hwu/Ptentm1Hwu
Scgb1a1tm1.1(cre)Fjd/Scgb1a1+

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
lung inflammation J:131721
Krastm4Tyj/Kras+
Stk11tm1.2Rdp/Stk11tm1.2Rdp

(involves: 129S4/SvJae * 129S6/SvEvTac)
increased macrophage cell number J:197037
Krastm4Tyj/Kras+
Tg(MUC1)79.24Gend/0

(involves: 129S4/SvJae * C57BL/6)
decreased interferon-gamma secretion J:154046
increased IgG level J:154046
increased IgM level J:154046
increased regulatory T cell number J:154046
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA)
abnormal myelopoiesis J:88163
enlarged spleen J:88163
increased granulocyte number J:88163
increased leukocyte cell number J:88163
increased spleen red pulp amount J:88163
lymphoid hyperplasia J:88163
myeloid hyperplasia J:88163
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
abnormal myelopoiesis J:87429
enlarged spleen J:87429, J:115071
increased leukocyte cell number J:87429
increased monocyte cell number J:87429
increased splenocyte proliferation J:87429
myeloid hyperplasia J:87429
Krastm4Tyj/Kras+
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * C57BL/6J * CBA/J)
enlarged spleen J:276349
Krastm4Tyj/Kras+
Tg(Scgb1a1-cre)1Kkw/?

(involves: 129 * C57BL/6 * FVB/N)
increased inflammatory response J:107260
Krastm4Tyj/Kras+
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm

(B6.129-Krastm4Tyj Tgfbr2tm1.2Hlm)
abnormal myeloid leukocyte morphology J:177379
increased B cell number J:177379
increased T cell number J:177379
Krastm4Tyj/Kras+
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Ptf1atm1.1(cre)Cvw/Ptf1a+

(involves: 129S/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
enlarged spleen J:116129
Krastm4Tyj/Kras+
Trp53tm2Tyj/Trp53+

(involves: 129S4/SvJae)
lung inflammation J:191425
Krastm4Tyj/Krastm4Tyj
Trim33tm1Los/Trim33tm1Los
Tg(Pdx1-cre)89.1Dam/0

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 * DBA/2)
pancreas inflammation J:151781
Krt1tm1Tmm/Krt1tm1Tmm
(involves: 129 * C57BL/6)
abnormal circulating interleukin level J:200244
abnormal interleukin secretion J:200244
increased circulating interleukin-18 level J:200244
Krt2tm1a(KOMP)Wtsi/Krt2tm1a(KOMP)Wtsi
(involves: C57BL/6N)
skin inflammation J:214772
Krt5tm1.1(KOMP)Vlcg/Krt5+
(C57BL/6N-Krt5tm1.1(KOMP)Vlcg/Tcp)
abnormal lymph node morphology J:211773
Krt8tm1b(EUCOMM)Hmgu/Krt8+
(C57BL/6N-Krt8tm1b(EUCOMM)Hmgu/Ics)
increased neutrophil cell number J:211773
Krt8tm1Rgo/Krt8tm1Rgo
(involves: 129S2/SvPas * C57BL/6 * FVB/N)
chronic inflammation J:86719, J:98058
enlarged spleen J:22116
Krt10tm1Tmm/Krt10+
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6))
increased susceptibility to infection J:31853
Krt18tm1Tmm/Krt18+
(involves: 129P2/OlaHsd)
liver inflammation J:309021
Krt18tm1Tmm/Krt18tm1Tmm
(involves: 129P2/OlaHsd)
liver inflammation J:309021
Krt27em1(IMPC)Ccpcz/Krt27em1(IMPC)Ccpcz
(C57BL/6N-Krt27em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
increased CD8-positive, alpha-beta T cell number J:211773
Krt28em1(IMPC)Ccpcz/Krt28em1(IMPC)Ccpcz
(C57BL/6N-Krt28em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Krt33aem1(IMPC)Ccpcz/Krt33aem1(IMPC)Ccpcz
(C57BL/6N-Krt33aem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Krt33aPlsh-3Btlr/Krt33a+
(C57BL/6J-Krt33aPlsh-3Btlr)
immune system phenotype J:145290
Krt33bem1(IMPC)Ccpcz/Krt33bem1(IMPC)Ccpcz
(C57BL/6N-Krt33bem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased eosinophil cell number J:211773
Krt34em1(IMPC)Ccpcz/Krt34em1(IMPC)Ccpcz
(C57BL/6NCrl-Krt34em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Krt72em1(IMPC)Ccpcz/Krt72em1(IMPC)Ccpcz
(C57BL/6N-Krt72em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Krt76tm1a(KOMP)Wtsi/Krt76tm1a(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
skin inflammation J:232539
Krtap7-1em1(IMPC)Ccpcz/Krtap7-1em1(IMPC)Ccpcz
(C57BL/6NCrl-Krtap7-1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small spleen J:211773
Krtap8-1em1(IMPC)Ccpcz/Krtap8-1em1(IMPC)Ccpcz
(C57BL/6N-Krtap8-1em1(IMPC)Ccpcz/Ccpcz)
decreased CD4-positive, alpha-beta T cell number J:211773
decreased T-helper cell number J:211773
immune system phenotype J:211773
Krtap9-5em1(IMPC)Ccpcz/Krtap9-5em1(IMPC)Ccpcz
(C57BL/6N-Krtap9-5em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Ksr1tm1Shaw/Ksr1tm1Shaw
(Not Specified)
decreased susceptibility to induced arthritis J:140520
decreased T cell proliferation J:75739
Ksr1tm1Shaw/Ksr1tm1Shaw
Tg(DO11.10)10Dlo/0

(involves: BALB/c * C3H * C57BL/6)
abnormal CD4-positive T cell differentiation J:75739
decreased interleukin-2 secretion J:75739
decreased T cell proliferation J:75739
Kyem1(IMPC)J/Ky+
(C57BL/6NJ-Kyem1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
L3mbtl1tm1.1Haho/L3mbtl1tm1.1Haho
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:166180
Lacc1em1Arkr/Lacc1em1Arkr
(C57BL/6NTac-Lacc1em1Arkr)
abnormal macrophage physiology J:244365
decreased circulating interleukin-1 beta level J:244365
decreased susceptibility to endotoxin shock J:244365
Lacc1em2Arkr/Lacc1em2Arkr
(C57BL/6NTac-Lacc1em2Arkr)
abnormal macrophage physiology J:244365
decreased circulating interleukin-1 beta level J:244365
decreased susceptibility to endotoxin shock J:244365
Lacc1em3Arkr/Lacc1em3Arkr
(C57BL/6NTac-Lacc1em3Arkr)
abnormal macrophage physiology J:244365
increased circulating interleukin-1 beta level J:244365
increased susceptibility to endotoxin shock J:244365
Lacc1em4Arkr/Lacc1em4Arkr
(C57BL/6NTac-Lacc1em4Arkr)
abnormal macrophage physiology J:244365
increased circulating interleukin-1 beta level J:244365
increased susceptibility to endotoxin shock J:244365
Lacc1tm1a(KOMP)Wtsi/Lacc1tm1a(KOMP)Wtsi
(involves: C57BL/6N * C57BL/6NTac)
abnormal macrophage morphology J:244365
abnormal macrophage physiology J:244365
decreased circulating tumor necrosis factor level J:244365
decreased interleukin-1 beta secretion J:244365
increased circulating interleukin-1 beta level J:244365
increased susceptibility to endotoxin shock J:244365
Lag3tm1Daav/Lag3+
Tg(Foxp3-EGFP/cre)1cJbs/0

(NOD.Cg-Lag3tm1Daav Tg(Foxp3-EGFP/cre)1cJbs)
decreased susceptibility to autoimmune diabetes J:260063
Lag3tm1Daav/Lag3tm1Daav
Tg(Foxp3-EGFP/cre)1cJbs/0

(NOD.Cg-Lag3tm1Daav Tg(Foxp3-EGFP/cre)1cJbs)
abnormal CD8-positive, alpha-beta T cell physiology J:260063
abnormal effector T cell number J:260063
abnormal interleukin level J:260063
abnormal tumor necrosis factor level J:260063
decreased susceptibility to autoimmune diabetes J:260063
Lag3tm1Doi/Lag3tm1Doi
(involves: 129S2/SvPas * C57BL/6)
abnormal NK cell physiology J:32509
abnormal T cell physiology J:89653
enlarged spleen J:89653
increased CD4-positive, alpha-beta T cell number J:89653
increased CD8-positive, alpha-beta T cell number J:89653
increased single-positive T cell number J:89653
Lage3em1(IMPC)Tcp/Lage3em1(IMPC)Tcp
(C57BL/6N-Lage3em1(IMPC)Tcp/Tcp)
increased neutrophil cell number J:211773
Lair1tm1.1Jco/Lair1tm1.1Jco
(involves: C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:180203
decreased CD8-positive, alpha-beta T cell number J:180203
decreased IgG1 level J:180203
decreased thymocyte number J:180203
increased activated T cell number J:180203
increased B cell number J:180203
increased CD4-positive, alpha-beta memory T cell number J:180203
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:180203
increased CD8-positive, alpha-beta memory T cell number J:180203
increased dendritic cell number J:180203
increased eosinophil cell number J:180203
increased marginal zone B cell number J:180203
Lair1tm1Jco/Lair1tm1Jco
Tg(Cd4-cre)1Cwi/?

(involves: C57BL/6 * DBA/2)
decreased IgG2a level J:180203
decreased IgG2b level J:180203
Lama2dy/Lama2dy
(involves: 129P1/ReJ)
increased IgG level J:102959
increased IgM level J:102959
Lama2tm1Eeng/Lama2tm1Eeng
(involves: 129S1/Sv)
myositis J:170192
Lama2tm1Stk/Lama2tm1Stk
(involves: 129P2/OlaHsd * BALB/c)
abnormal thymus corticomedullary boundary morphology J:61802
abnormal thymus physiology J:61802
decreased double-positive T cell number J:61802
decreased T cell number J:61802
thymus cortex hypoplasia J:61802
Lama3tm1.1Grsb/Lama3tm1.1Grsb
(involves: C57BL/6)
abnormal chemokine level J:235712
abnormal tumor necrosis factor level J:235712
increased alveolar macrophage number J:235712
lung inflammation J:235712
Lama3tm1Arte/Lama3tm1Arte
Tg(KRT14-cre/ERT)20Efu/0

(involves: C57BL/6 * CD-1)
skin inflammation J:240054
Lama4tm1.1(KOMP)Vlcg/Lama4tm1.1(KOMP)Vlcg
(C57BL/6N-Lama4tm1.1(KOMP)Vlcg/Ucd)
increased basophil cell number J:211773
Lama5b2b2966.1Clo/Lama5b2b2966.1Clo
(C57BL/6J-Lama5b2b2966.1Clo)
thymus hypoplasia J:175213
Lama5tm1Lsor/Lama5tm1Lsor
Tg(Tek-cre)1Ywa/0

(involves: C57BL/6 * SJL)
abnormal marginal zone B cell physiology J:198783
decreased marginal zone B cell number J:198783
decreased transitional stage T2 B cell number J:198783
increased B cell number J:198783
increased IgM level J:198783
increased transitional stage T1 B cell number J:198783
Lama5tm2Jhm/Lama5tm1Jhm
Tg(NPHS2-cre)295Lbh/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL)
tubulointerstitial nephritis J:185850
Lamb2tm1Jrs/Lamb2tm1Jrs
(involves: 129S1/Sv * 129X1/SvJ)
glomerulonephritis J:23783
Lamc2jeb/Lamc2jeb
(129X1/SvJ-Lamc2jeb)
ear inflammation J:158873
Lamp1em1(IMPC)Mbp/Lamp1em1(IMPC)Mbp
(C57BL/6N-Lamp1em1(IMPC)Mbp/MbpMmucd)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
small spleen J:211773
Lamp2tm1Psa/Lamp2tm1Psa
(either: (involves: 129P2/OlaHsd * 129/Sv * C57BL/6J) or (involves: 129P2/OlaHsd * 129/Sv))
abnormal thymus morphology J:64151
intermingled spleen red and white pulp J:64151
Lamp3em1(IMPC)Tcp/Lamp3em1(IMPC)Tcp
(C57BL/6N-Lamp3em1(IMPC)Tcp/Tcp)
abnormal lymph node morphology J:211773
Lamp3em1Damme/Lamp3em1Damme
(involves: C57BL/6N)
increased macrophage cell number J:324174
Lancl1tm1.1Pfw/Lancl1tm1.1Pfw
(involves: 129 * C57BL/6)
brain inflammation J:214805
Lancl2tm2a(KOMP)Wtsi/Lancl2tm2a(KOMP)Wtsi
(involves: C57BL/6N)
decreased macrophage cell number J:250673
decreased regulatory T cell number J:250673
decreased susceptibility to bacterial infection J:250673
Lancl2tm2c(KOMP)Wtsi/Lancl2tm2c(KOMP)Wtsi
Lyz2tm1(cre)Ifo/Lyz2+

(involves: C57BL/6N)
decreased macrophage cell number J:250673
decreased regulatory T cell number J:250673
decreased susceptibility to bacterial infection J:250673
Lao1tm1Oka/Lao1tm1Oka
(involves: 129S2/SvPas * C57BL/6J)
abnormal interleukin level J:260668
increased susceptibility to bacterial infection J:260668
increased susceptibility to bacterial infection induced morbidity/mortality J:260668
mastitis J:260668
Lap3tm1Klr/Lap3tm1Klr
(involves: 129 * C57BL/6)
immune system phenotype J:119392
Laptm5tm1Jow/Laptm5tm1Jow
(C57BL/6-Laptm5tm1Jow)
abnormal T cell activation J:137841
abnormal type IV hypersensitivity reaction J:137841
immune system phenotype J:137841
increased interleukin-2 secretion J:137841
increased T cell proliferation J:137841
Laq1MRL/Laq1MRL
(involves: C57BL/6 * MRL)
increased susceptibility to autoimmune disorder J:45708
LarSAMP1/?
(involves: C57BL/10 * SAMP1)
abnormal humoral immune response J:1953
Large1myd/Large1myd
(MYD/Le-Os +/+ Largemyd/J)
myositis J:5670
Large1myd/Large1myd
(B6C3Fe a/a-Large1myd/J)
myositis J:27793
Larp1em1(IMPC)Mbp/Larp1+
(C57BL/6N-Larp1em1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Lat2tm1Mal/Lat2tm1Mal
(involves: 129S2/SvPas)
abnormal mast cell physiology J:93950
Lat2tm1Mal/Lat2tm1Mal
(B6.129S2-Lat2tm1Mal)
increased anti-nuclear antigen antibody level J:126321
Lat2tm1Mal/Lat2tm1Mal
Lime1tm1.1Mal/Lime1tm1.1Mal

(involves: 129 * C57BL/6)
increased anti-nuclear antigen antibody level J:126321
Lat2tm1Wz/Lat2tm1Wz
(involves: C57BL/6)
abnormal mast cell physiology J:93951
Lat2tm1Wz/Lat2tm1Wz
(B6.Cg-Lat2tm1Wz)
abnormal CD8-positive, alpha-beta T cell physiology J:116157
abnormal cytokine secretion J:116157
abnormal T cell physiology J:116157
increased anti-double stranded DNA antibody level J:116157
increased autoantibody level J:116157
increased T cell proliferation J:116157
spleen hyperplasia J:116157
Lat2tm1Wz/Lat2tm1Wz
(Not Specified)
abnormal T cell physiology J:181866
decreased interleukin-12 secretion J:181866
increased circulating interleukin-6 level J:181866
increased circulating tumor necrosis factor level J:181866
increased interferon-gamma secretion J:181866
increased interleukin-10 secretion J:181866
increased mast cell degranulation J:181866
increased susceptibility to endotoxin shock J:181866
Lat2tm2Wz/Lat2tm2Wz
Tg(Lck-cre)548Jxm/0

(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:116157
enlarged spleen J:116157
increased activated T cell number J:116157
increased anti-double stranded DNA antibody level J:116157
Lat2tm3.1Wz/Lat2tm3.1Wz
(B6.Cg-Lat2tm3.1Wz)
abnormal T cell physiology J:181866
enlarged spleen J:181866
immune system phenotype J:181866
increased interferon-gamma secretion J:181866
increased mast cell degranulation J:181866
increased memory T cell number J:181866
increased susceptibility to endotoxin shock J:181866
Lattm1.1Lov/Lattm1.1Lov
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:116157, J:77099
abnormal CD8-positive, alpha beta T cell morphology J:77099
abnormal cytokine secretion J:77099
abnormal double-negative T cell morphology J:77099
abnormal immunoglobulin level J:77099
abnormal lymph organ size J:77099
abnormal T cell differentiation J:77099
abnormal T cell physiology J:77099
decreased double-positive T cell number J:77099
decreased T cell proliferation J:77099
decreased thymocyte number J:77099
enlarged lymph nodes J:116157, J:77099
enlarged spleen J:116157, J:77099
increased activated T cell number J:77099
increased anti-double stranded DNA antibody level J:116157
increased anti-nuclear antigen antibody level J:77099
increased autoantibody level J:77099
increased IgE level J:77099
increased IgG1 level J:77099
increased IgM level J:77099
increased T cell proliferation J:77099
small thymus J:77099
spleen hyperplasia J:116157
Lattm1.1Lov/Lattm1.1Lov
Lat2tm1Wz/Lat2tm1Wz

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:116157
enlarged lymph nodes J:116157
enlarged spleen J:116157
increased anti-double stranded DNA antibody level J:116157
spleen hyperplasia J:116157
Lattm1.1Mal/Lattm1.1Mal
(involves: 129S2/SvPas)
abnormal B cell activation J:77098
abnormal gamma-delta T cell differentiation J:77098
abnormal immune serum protein physiology J:77098
abnormal immune system organ morphology J:77098
abnormal lymph node germinal center morphology J:125722
abnormal lymph node secondary follicle morphology J:125722
abnormal lymphocyte morphology J:77098
abnormal spleen periarteriolar lymphoid sheath morphology J:125722
abnormal T cell selection J:77098
abnormal T cell subpopulation ratio J:77098
abnormal T-helper 2 physiology J:125722
chronic inflammation J:77098
decreased double-positive T cell number J:77098
enlarged lymph nodes J:77098
enlarged spleen J:77098
glomerulonephritis J:125722
increased anti-chromatin antibody level J:125722
increased anti-erythrocyte antigen antibody level J:125722
increased anti-nuclear antigen antibody level J:125722
increased B cell number J:77098
increased CD4-positive, alpha-beta T cell number J:125722, J:77098
increased eosinophil cell number J:77098
increased IgE level J:125722, J:77098
increased IgG1 level J:262891, J:125722, J:77098
increased IgM level J:125722
increased inflammatory response J:262891
increased interferon-gamma secretion J:77098
increased interleukin-4 secretion J:77098
increased memory T cell number J:77098
increased plasma cell number J:125722
increased spleen germinal center number J:125722
increased spleen weight J:262891
increased susceptibility to autoimmune hemolytic anemia J:125722
increased T cell proliferation J:77098
increased T-helper 2 cell number J:77098
kidney inflammation J:262891
liver inflammation J:125722
lung inflammation J:125722
pancreas inflammation J:262891
phlebitis J:262891
salivary gland inflammation J:262891
spleen hyperplasia J:77098
thymus hypoplasia J:77098
Lattm1.1Mal/Lattm1.1Mal
(involves: 129S2/SvPas * C57BL/6)
abnormal T cell proliferation J:131351
abnormal T-helper 2 physiology J:131351
Lattm1.1Mal/Lattm6.1(HBEGF/EGFP)Mal
(involves: 129S2/SvPas * C57BL/6)
abnormal T-helper 2 physiology J:151840
Lattm1Bpay/Lattm1Bpay
(involves: 129S2/SvPas)
abnormal T cell differentiation J:103904
arrested T cell differentiation J:103904
decreased double-negative T cell number J:103904
decreased T cell number J:103904
decreased thymocyte number J:103904
immune system phenotype J:103904
small thymus J:103904
Lattm1Les/Lattm1.1Wz
(involves: C57BL/6)
abnormal effector T cell morphology J:147946
Lattm1Les/Lattm1.1Wz
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal effector T cell morphology J:147946
abnormal T cell differentiation J:147946
abnormal T cell physiology J:147946
decreased CD4-positive, alpha-beta T cell number J:147946
decreased CD8-positive, alpha-beta T cell number J:147946
decreased regulatory T cell number J:147946
decreased thymocyte number J:147946
increased double-positive T cell number J:147946
increased gamma-delta T cell number J:147946
small thymus J:147946
Lattm1Les/Lattm1.2Wz
(involves: C57BL/6 * FVB/N)
absent T cells J:147946
arrested T cell differentiation J:147946
Lattm1Les/Lattm1Les
(Not Specified)
abnormal T cell morphology J:54059
arrested T cell differentiation J:116964, J:54059
decreased double-negative T cell number J:54059
decreased T cell number J:54059
decreased thymocyte number J:54059
small thymus J:54059
Lattm1Les/Lattm1Les
Lat2tm1Wz/Lat2tm1Wz

(involves: C57BL/6)
abnormal mast cell physiology J:93951
Lattm1Les/Lattm1Les
Lcp2tm5(Lat/Lcp2)Gak/Lcp2tm5(Lat/Lcp2)Gak

(involves: 129S1/Sv * 129X1/SvJ)
arrested T cell differentiation J:147721
decreased double-positive T cell number J:147721
Lattm1Les/Lattm1Les
Tg(CD2-LAT2)1Wz/0

(Not Specified)
abnormal B cell physiology J:116964
abnormal interferon secretion J:116964
abnormal interleukin secretion J:116964
abnormal leukocyte physiology J:116964
abnormal single-positive T cell number J:116964
abnormal spleen periarteriolar lymphoid sheath morphology J:116964
abnormal T cell differentiation J:116964
decreased double-positive T cell number J:116964
enlarged spleen J:116964
increased IgG1 level J:116964
increased IgM level J:116964
increased interleukin-4 secretion J:116964
increased interleukin-10 secretion J:116964
small thymus J:116964
spleen hyperplasia J:116964
Lattm2.1Lov/Lattm2.1Lov
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
abnormal T cell differentiation J:77695
decreased T cell number J:77695
small thymus J:77695
Lattm2.1Mal/Lattm2.1Mal
(involves: 129S2/SvPas)
abnormal B cell activation J:94074
abnormal B cell differentiation J:94074
abnormal gamma-delta T cell differentiation J:94074
abnormal immune system organ morphology J:94074
abnormal lymphocyte morphology J:94074
abnormal lymphopoiesis J:94074
abnormal mature gamma-delta T cell morphology J:94074
abnormal plasma cell morphology J:94074
abnormal spleen morphology J:94074
abnormal spleen periarteriolar lymphoid sheath morphology J:94074
abnormal spleen white pulp morphology J:94074
abnormal T cell activation J:94074
abnormal T-helper 2 cell morphology J:94074
abnormal thymocyte activation J:94074
absent CD4-positive, alpha-beta T cells J:94074
absent CD8-positive, alpha-beta T cells J:94074
arrested T cell differentiation J:94074
decreased double-positive T cell number J:94074
enlarged lymph nodes J:94074
enlarged spleen J:94074
increased B cell number J:94074
increased IgE level J:94074
increased IgG1 level J:94074
increased immunoglobulin level J:94074
increased interleukin-4 secretion J:94074
increased mature gamma-delta T cell number J:94074
thymus hypoplasia J:94074
Lattm2.1Mal/Lattm2.1Mal
Lat2tm1Mal/Lat2tm1Mal

(involves: 129S2/SvPas)
abnormal mast cell physiology J:93950
Lattm3.1Mal/Lattm3.1Mal
(involves: 129S2/SvPas)
abnormal gamma-delta T cell differentiation J:94074
abnormal lymph node cell ratio J:94074
abnormal splenic cell ratio J:94074
abnormal thymocyte activation J:94074
abnormal thymus cell ratio J:94074
absent CD4-positive, alpha-beta T cells J:94074
absent CD8-positive, alpha-beta T cells J:94074
absent mature gamma-delta T cells J:94074
arrested T cell differentiation J:94074
decreased double-positive T cell number J:94074
decreased T cell number J:94074
increased T cell number J:94074
Lattm4.1Mal/Lattm4.1Mal
(involves: 129P2/OlaHsd)
abnormal gamma-delta T cell differentiation J:94074
abnormal lymph node cell ratio J:94074
abnormal lymphocyte morphology J:94074
abnormal splenic cell ratio J:94074
abnormal thymocyte activation J:94074
abnormal thymus cell ratio J:94074
absent CD4-positive, alpha-beta T cells J:94074
absent CD8-positive, alpha-beta T cells J:94074
absent mature gamma-delta T cells J:94074
arrested T cell differentiation J:94074
decreased double-positive T cell number J:94074
decreased T cell number J:94074
Lattm4.1Mal/Lattm4.1Mal
Tg(Lck*F505)3073Rmp/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal T-helper 2 physiology J:151840
increased CD4-positive, alpha-beta T cell number J:151840
increased IgE level J:151840
increased IgG1 level J:151840
increased interleukin-4 secretion J:151840
spleen hyperplasia J:151840
Lattm4.1Mal/Lattm4.1Mal
Trdctm1Mal/Trdctm1Mal

(involves: 129P2/OlaHsd * C57BL/6)
abnormal double-negative T cell morphology J:112658
Lattm4.1Mal/Lattm6.1(HBEGF/EGFP)Mal
(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
abnormal T-helper 2 physiology J:151840
Lattm5.1Mal/Lattm5.1Mal
(involves: C57BL/6)
arrested T cell differentiation J:152363
Lattm6.1(HBEGF/EGFP)Mal/?
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6)
abnormal T cell physiology J:138401
Lattm6.1(HBEGF/EGFP)Mal/Lattm6.1(HBEGF/EGFP)Mal
(involves: 129S2/SvPas * C57BL/6)
abnormal T cell activation J:151840
abnormal T-helper 2 physiology J:151840
decreased interferon-gamma secretion J:151840
Lattm8.1(CD2,-ECFP)Mal/Lattm8.1(CD2,-ECFP)Mal
(involves: 129S2/SvPas * C57BL/6)
abnormal lymphocyte morphology J:152149
abnormal T cell receptor delta chain V(D)J recombination J:152149
abnormal T cell receptor gamma chain V-J recombination J:152149
arrested T cell differentiation J:152149
increased double-negative T cell number J:152149
Lattm9Mal/Lattm9Mal
(involves: C57BL/6)
abnormal B cell number J:205441
abnormal immune system morphology J:205441
abnormal immune system physiology J:205441
abnormal lymphopoiesis J:205441
increased T-helper 2 cell number J:205441
Lattm9Mal/Lattm9Mal
Carmil2bas/Carmil2bas

(involves: C3HeB/FeJ * C57BL/6)
immune system phenotype J:205441
Lats1em1(IMPC)H/Lats1em1(IMPC)H
(C57BL/6NTac-Lats1em1(IMPC)H/H)
increased neutrophil cell number J:211773
Lax1tm1Wz/Lax1tm1Wz
(involves: C57BL/6)
abnormal B cell physiology J:98403
abnormal spleen germinal center morphology J:98403
abnormal splenic cell ratio J:98403
abnormal T cell activation J:98403
abnormal T cell physiology J:98403
increased IgE level J:98403
increased IgG1 level J:98403
increased IgG2a level J:98403
Laynem1Romd/Laynem1Romd
Tg(Cd8a-cre,-GFP)1Yzo/0

(involves: C57BL/6)
abnormal CD8-positive, alpha-beta T cell physiology J:302853
immune system phenotype J:302853
Lbca1C57BL/6Igc/Lbca1C57BL/6Igc
(involves: BALB/cIgc * C57BL/6Igc)
abnormal B cell activation J:139348
increased B cell proliferation J:139348
Lbca2BALB/cIgc/Lbca2C57BL/6Igc
(involves: BALB/cIgc * C57BL/6Igc)
abnormal B cell activation J:139348
increased B cell proliferation J:139348
Lbca2C57BL/6Igc/Lbca2C57BL/6Igc
(involves: BALB/cIgc * C57BL/6Igc)
abnormal B cell activation J:139348
increased B cell proliferation J:139348
Lbptm1b(EUCOMM)Hmgu/Lbptm1b(EUCOMM)Hmgu
(C57BL/6N-Lbptm1b(EUCOMM)Hmgu/H)
increased spleen weight J:211773
Lbptm1Buru/Lbptm1Buru
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immune serum protein physiology J:44878
decreased tumor necrosis factor secretion J:44878
Lbptm1Buru/Lbptm1Buru
(involves: 129S1/Sv * 129X1/SvJ * BALB/c)
decreased susceptibility to type I hypersensitivity reaction J:67090
Lbptm1Buru/Lbptm1Buru
(B6.129-Lbptm1Buru)
abnormal acute inflammation J:129411
abnormal chemokine level J:129411
abnormal innate immunity J:129411
abnormal neutrophil physiology J:129411
abnormal tumor necrosis factor secretion J:129411
Lbptm1Jack/Lbptm1Jack
(involves: 129P2/OlaHsd * BALB/c)
increased susceptibility to bacterial infection J:43514
Lbrem1(IMPC)Tcp/Lbrem1(IMPC)Tcp
(C57BL/6N-Lbrem1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
LbrGt(XE569)Byg/LbrGt(XE569)Byg
(involves: 129P2/OlaHsd * C57BL/6Cr)
abnormal granulocyte differentiation J:138854
abnormal granulocyte morphology J:138854
abnormal lymphocyte morphology J:138854
abnormal neutrophil morphology J:138854
enlarged lymph nodes J:138854
Lbric-2J/Lbric-2J
(involves: A/J)
abnormal immune system cell morphology J:80915
Lbric-3J/Lbric-3J
(involves: A/J)
abnormal immune system cell morphology J:80915
Lbric-J/Lbr+
(C57BL/6J-Lbric-J)
abnormal granulocyte morphology J:80915
Lbric-J/Lbr+
((NZW/LacJ x C57BL/6J-Lbric-J/J)F1)
abnormal neutrophil morphology J:234168
enlarged spleen J:234168
increased anti-chromatin antibody level J:234168
increased anti-nuclear antigen antibody level J:234168
increased autoantibody level J:234168
increased susceptibility to systemic lupus erythematosus J:234168
Lbric-J/Lbr+
Tm7sf2tm1Fdp/Tm7sf2tm1Fdp

(involves: 129S4/SvJae * C57BL/6)
abnormal spleen morphology J:143838
Lbric-J/Lbric-J
(C57BL/6J-Lbric-J)
abnormal eosinophil morphology J:80915
abnormal lymphocyte morphology J:80915
abnormal neutrophil morphology J:80915
Lbric-J/Lbric-J
(involves: 129S4/SvJae * C57BL/6)
abnormal neutrophil differentiation J:143838
abnormal spleen morphology J:143838
Lbric-J/Lbrlym3
(C57BL/6-Lbric-J/Lbrlym3)
decreased leukocyte cell number J:180355
decreased lymphocyte cell number J:180355
Lbrlym3/Lbr+
(C57BL/6-Lbrlym3)
abnormal neutrophil morphology J:180355
Lbrlym3/Lbrlym3
(C57BL/6-Lbrlym3)
abnormal B cell physiology J:180355
abnormal lymphocyte cell number J:180355
abnormal lymphocyte morphology J:180355
abnormal neutrophil morphology J:180355
abnormal T cell physiology J:180355
decreased B cell number J:180355
decreased CD4-positive, alpha-beta T cell number J:180355
decreased CD8-positive, alpha-beta T cell number J:180355
decreased leukocyte cell number J:180355
decreased lymphocyte cell number J:180355
decreased T cell number J:180355
decreased T cell proliferation J:180355
lymph node hypoplasia J:180355
spleen hypoplasia J:180355
thymus hypoplasia J:180355
Lbw2NZB/BlScr/Lbw2NZB/BlScr
(involves: NZB * NZW)
glomerulonephritis J:45708
increased anti-chromatin antibody level J:98150
increased autoantibody level J:98150
increased spleen weight J:98150
Lbw2NZB/BlScr/Lbw2NZW/LacScr
(involves: NZB * NZW)
glomerulonephritis J:20991
increased anti-chromatin antibody level J:98150
increased autoantibody level J:98150
Lbw2NZW/LacScr/Lbw2NZW/LacScr
(involves: NZB * NZW)
decreased autoantibody level J:98150
decreased IgG level J:98150
decreased IgM level J:98150
Lbw4NZW/LacScr/?
(involves: C57BL/6J * NZM2410/Aeg)
decreased immunoglobulin level J:52863
Lbw5NZW/LacScr/Lbw5NZB/BlScr
(involves: NZB/BlScr * NZW/LacScr)
increased susceptibility to systemic lupus erythematosus J:20991
Lbw5NZW/LacScr/Lbw5NZW/LacScr
(involves: NZB/BlScr * NZW/LacScr)
increased susceptibility to systemic lupus erythematosus J:20991
Lbw6NZW/LacScr/Lbw6NZW/LacScr
(involves: NZB/BlScr * NZW/LacScr)
increased susceptibility to systemic lupus erythematosus J:20991
Lbw7NZB/BlScr/Lbw7NZB/BlScr
(involves: NZB/BlScr * NZW/LacScr)
increased susceptibility to systemic lupus erythematosus J:20991
Lbw7NZB/BlScr/Lbw7NZW/LacScr
(involves: NZB/BlScr * NZW/LacScr)
increased susceptibility to systemic lupus erythematosus J:20991
Lbw8NZB/BlScr/Lbw8NZB/BlScr
(involves: NZB/BlScr * NZW/LacScr)
increased susceptibility to autoimmune disorder J:20991
Lbw8NZB/BlScr/Lbw8NZW/LacScr
(involves: NZB/BlScr * NZW/LacScr)
increased susceptibility to autoimmune disorder J:20991
Lckm1Btlr/Lckm1Btlr
(C57BL/6J-Lckm1Btlr)
abnormal CD4-positive T cell differentiation J:144695
abnormal CD8-positive, alpha-beta T cell differentiation J:144695
decreased CD4-positive, alpha-beta T cell number J:144695
decreased CD8-positive, alpha-beta T cell number J:144695
decreased cytotoxic T cell cytolysis J:144695
thymus atrophy J:144695
thymus hypoplasia J:144695
Lckm2Btlr/Lckm2Btlr
(C57BL/6J-Lckm2Btlr)
decreased CD4-positive, alpha-beta T cell number J:203759
decreased CD8-positive, alpha-beta T cell number J:203759
decreased IgG level J:203759
Lckm3Btlr/Lckm3Btlr
(C57BL/6J-Lckm3Btlr)
abnormal T cell subpopulation ratio J:217863
decreased single-positive T cell number J:217863
increased activated T cell number J:217863
increased single-positive T cell number J:217863
Lcktm1.1Litt/Lcktm1.1Litt
(Not Specified)
abnormal immunoglobulin level J:152472
abnormal lymphocyte morphology J:152472
abnormal thymus morphology J:152472
Lcktm1Dbs/Lcktm1Dbs
(involves: C3H * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:114660
abnormal CD8-positive, alpha beta T cell morphology J:114660
abnormal double-negative T cell morphology J:114660
abnormal T cell differentiation J:114660
decreased T cell number J:114660
decreased T cell proliferation J:114660
decreased thymocyte number J:114660
Lcktm1Dbs/Lcktm1Dbs
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C3H * C57BL/6 * DBA/2J)
abnormal positive T cell selection J:114660
abnormal T cell differentiation J:114660
arrested T cell differentiation J:114660
Lcktm1Dbs/Lcktm1Dbs
Tg(TcraTcrb)425Cbn/0

(involves: C3H * C57BL/6)
abnormal positive T cell selection J:114660
arrested T cell differentiation J:114660
Lcktm1Dbs/Lcktm1Dbs
Tg(TcraTcrb)1100Mjb/0

(involves: C3H * C57BL/6)
abnormal positive T cell selection J:114660
decreased T cell proliferation J:114660
Lcktm1Litt/Lcktm1.1Litt
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129X1/SvJ)
abnormal regulatory T cell physiology J:152472
decreased regulatory T cell number J:152472
decreased T cell proliferation J:152472
enlarged lymph nodes J:152472
increased regulatory T cell number J:152472
increased T cell number J:152472
Lcktm1Mak/Lcktm1Mak
(involves: 129S2/SvPas)
abnormal alpha-beta intraepithelial T cell morphology J:112977
abnormal double-negative T cell morphology J:110847
abnormal lymphocyte morphology J:1119
abnormal single-positive T cell number J:37062
abnormal T cell morphology J:110847
abnormal thymocyte activation J:110847
decreased CD4-positive, alpha-beta T cell number J:37940
decreased CD8-positive, alpha-beta T cell number J:37940
decreased double-positive T cell number J:1119, J:110847
decreased gamma-delta intraepithelial T cell number J:112977, J:37940
decreased gamma-delta T cell number J:37062
decreased IgG1 level J:1119
decreased T cell number J:1119, J:37062
decreased thymocyte number J:1119
increased IgG2a level J:1119
increased IgG3 level J:1119
increased IgM level J:1119
thymus atrophy J:1119
thymus hypoplasia J:37062, J:37940
Lcktm1Mak/Lcktm1Mak
(B6.129S2-Lcktm1Mak)
abnormal intraepithelial T cell morphology J:111646
abnormal intraepithelial T cell number J:111646
abnormal T cell differentiation J:111646
decreased cytotoxic T cell cytolysis J:111646
decreased gamma-delta intraepithelial T cell number J:111646
Lcktm1Mak/Lcktm1Mak
Rag1tm1Mom/Rag1+
Tg(Lck-Fyn*Y528F)5525Cjg/0

(involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6)
abnormal T cell differentiation J:37062
decreased T cell number J:37062
Lcmt1em1(IMPC)Rbrc/Lcmt1+
(C57BL/6NJcl-Lcmt1em1(IMPC)Rbrc/Rbrc)
abnormal large unstained cell number J:211773
increased spleen weight J:211773
Lcn2tm1Aade/Lcn2tm1Aade
(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to bacterial infection J:95107
sepsis J:95107
Lcn2tm1Aade/Lcn2tm1Aade
(B6.129P2-Lcn2tm1Aade)
increased spleen weight J:169355
Lcn2tm1Mak/Lcn2tm1Mak
(involves: 129P2/OlaHsd * C57BL/6J)
increased susceptibility to bacterial infection J:106079
Lcn2tm1Mrgr/Lcn2tm1Mrgr
(129(B6)-Lcn2tm1Mrgr)
abnormal mast cell physiology J:173490
abnormal myelopoiesis J:173490
decreased thymocyte apoptosis J:173490
increased B cell number J:173490
increased leukocyte cell number J:173490
increased lymphocyte cell number J:173490
increased macrophage cell number J:173490
increased monocyte cell number J:173490
increased neutrophil cell number J:173490
increased splenocyte number J:173490
myeloid hyperplasia J:173490
spleen hyperplasia J:173490
thymus hyperplasia J:173490
Lcn2tm1Mrgr/Lcn2tm1Mrgr
(B6.129-Lcn2tm1Mrgr)
abnormal mast cell physiology J:173490
Lcn2tm1Mrgr/Lcn2tm1Mrgr
(involves: 129 * C57BL/6)
abnormal mast cell physiology J:173490
Lcp1tm1Erjb/Lcp1tm1Erjb
(involves: 129X1/SvJ)
abnormal macrophage physiology J:161042
abnormal neutrophil physiology J:161042
decreased interleukin-1 secretion J:161042
immune system phenotype J:161042
increased susceptibility to bacterial infection J:161042
Lcp2m1Khoe/Lcp2m1Khoe
(C57BL/6J-Lcp2m1Khoe)
abnormal NK cell physiology J:196519
impaired natural killer cell mediated cytotoxicity J:196519
Lcp2tm1.1Wz/Lcp2tm1.1Wz
(B6.Cg-Lcp2tm1.1Wz)
abnormal effector T cell morphology J:150304
abnormal T cell differentiation J:150304
abnormal T cell subpopulation ratio J:150304
decreased CD4-positive, alpha-beta T cell number J:150304
decreased CD8-positive, alpha-beta T cell number J:150304
decreased double-negative T cell number J:150304
decreased interleukin-2 secretion J:150304
decreased T cell number J:150304
decreased T cell proliferation J:150304
decreased thymocyte number J:150304
immune system phenotype J:150304
increased double-negative T cell number J:150304
lymph node hypoplasia J:150304
small thymus J:150304
Lcp2tm1.1Wz/Lcp2tm1.1Wz
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C57BL/6 * C57BL/6J * DBA/2J)
abnormal T cell differentiation J:150304
Lcp2tm1Gak/Lcp2tm2Gak
Tg(Pf4-icre)Q3Rsko/0
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal lymphatic vessel morphology J:162815
abnormal Peyer's patch morphology J:162815
Lcp2tm1Gak/Lcp2tm2Gak
Tg(VAV1-cre)1Graf/0
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+

(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymphatic vessel morphology J:162815
Lcp2tm1Geha/Lcp2tm1Geha
(involves: 129S4/SvJae)
decreased interferon-gamma secretion J:131621
impaired natural killer cell mediated cytotoxicity J:131621
increased NK cell number J:131621
Lcp2tm2Gak/Lcp2tm2Gak
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:107467
decreased T cell apoptosis J:107467
increased CD8-positive, alpha-beta T cell number J:107467
increased gamma-delta T cell number J:107467
thymus hypoplasia J:107467
Lcp2tm3Gak/Lcp2tm3Gak
(involves: 129S6/SvEvTac * C57BL/6)
abnormal double-negative T cell morphology J:132995
abnormal negative T cell selection J:132995
abnormal T cell activation J:132995
abnormal T cell subpopulation ratio J:132995
decreased NK T cell number J:132995
Lcp2tm3Gak/Lcp2tm3Gak
(involves: 129S6/SvEvTac * BALB/c * C57BL/6)
abnormal negative T cell selection J:132995
Lcp2tm3Gak/Lcp2tm3Gak
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2J)
abnormal negative T cell selection J:132995
immune system phenotype J:132995
increased CD8-positive, alpha-beta T cell number J:132995
increased double-positive T cell number J:132995
Lcp2tm3Gak/Lcp2tm3Gak
Tg(TcrAND)53Hed/?

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
abnormal positive T cell selection J:132995
abnormal thymocyte activation J:132995
Lcp2tm3Gak/Lcp2tm4Gak
(involves: 129S6/SvEvTac * C57BL/6 * FVB/N)
immune system phenotype J:132995
Lcp2tm4Gak/Lcp2tm4Gak
(involves: 129S6/SvEvTac * C57BL/6 * FVB/N)
abnormal double-negative T cell morphology J:132995
abnormal negative T cell selection J:132995
abnormal T cell activation J:132995
abnormal T cell subpopulation ratio J:132995
decreased NK T cell number J:132995
Lcp2tm4Gak/Lcp2tm4Gak
(involves: 129S6/SvEvTac * BALB/c * C57BL/6)
abnormal negative T cell selection J:132995
Lcp2tm4Gak/Lcp2tm4Gak
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129S6/SvEvTac * C57BL/6 * DBA * FVB/N)
abnormal negative T cell selection J:132995
increased double-positive T cell number J:132995
Lcp2tm4Gak/Lcp2tm4Gak
Tg(TcrAND)53Hed/?

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
abnormal positive T cell selection J:132995
abnormal thymocyte activation J:132995
Lcp2tm5(Lat/Lcp2)Gak/Lcp2tm5(Lat/Lcp2)Gak
(involves: 129S1/Sv * 129X1/SvJ)
abnormal thymocyte activation J:147721
arrested T cell differentiation J:147721
decreased double-positive T cell number J:147721
decreased single-positive T cell number J:147721
thymus hypoplasia J:147721
Lcp2twm/Lcp2twm
(C57BL/6JSfdAnu-Lcp2twm/Anu)
abnormal double-positive T cell morphology J:104190
abnormal negative T cell selection J:104190
abnormal positive T cell selection J:104190
abnormal T cell physiology J:104190
arrested T cell differentiation J:104190
autoimmune response J:104190
decreased T cell number J:104190
decreased thymocyte number J:104190
increased IgE level J:104190
increased IgG level J:104190
Lctlp1DBA/1J/Lctlp1DBA/1J
(involves: DBA/1J * FVB/NJ)
increased CD8-positive, alpha-beta T cell number J:122919
Lctlp1DBA/1J/Lctlp1FVB/NJ
(involves: DBA/1J * FVB/NJ)
increased CD8-positive, alpha-beta T cell number J:122919
Lctlp1FVB/NJ/Lctlp1FVB/NJ
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:122919
Lctlp2DBA/1J/Lctlp2DBA/1J
(involves: DBA/1J * FVB/NJ)
increased CD8-positive, alpha-beta T cell number J:122919
Lctlp2DBA/1J/Lctlp2FVB/NJ
(involves: DBA/1J * FVB/NJ)
increased CD8-positive, alpha-beta T cell number J:122919
Lctlp2FVB/NJ/Lctlp2FVB/NJ
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:122919
Ldb3tm2b(EUCOMM)Hmgu/Ldb3+
(C57BL/6N-Ldb3tm2b(EUCOMM)Hmgu/Bay)
increased basophil cell number J:211773
increased large unstained cell number J:211773
Ldhaa-m1Neu/Ldhaa-m1Neu
(involves: 101/El * C3H/El)
abnormal leukocyte morphology J:132674
increased neutrophil cell number J:132674
increased spleen weight J:132674
spleen hyperplasia J:132674
LdlrHlb301/Ldlr+
(C57BL/6J-LdlrHlb301/J)
increased macrophage derived foam cell number J:82961
LdlrHlb301/LdlrHlb301
(C57BL/6J-LdlrHlb301/J)
increased macrophage derived foam cell number J:82961
Ldlrtm1Her/Ldlrtm1Her
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal microglial cell morphology J:116493
liver inflammation J:175559
Ldlrtm1Her/Ldlrtm1Her
(B6.129S7-Ldlrtm1Her)
abnormal microglial cell morphology J:137264
decreased circulating interleukin-10 level J:130794
increased circulating interleukin-1 beta level J:137264
increased circulating interleukin-6 level J:137264
increased circulating tumor necrosis factor level J:137264
Ldlrtm1Her/Ldlrtm1Her
Lrp1tm2Her/Lrp1tm2Her
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S7/SvEvBrd)
impaired macrophage phagocytosis J:137404
Ldlrtm1Her/Ldlrtm1Her
Lrp1tm2Her/Lrp1tm2Her
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J)
abnormal microglial cell physiology J:144185
Ldlrtm1Her/Ldlrtm1Her
Mapkapk2tm1Mgl/Mapkapk2tm1Mgl

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
abnormal macrophage derived foam cell morphology J:142788
decreased macrophage cell number J:142788
Ldlrtm1Her/Ldlrtm1Her
Olr1tm1Meht/Olr1tm1Meht

(involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6)
increased circulating interleukin-10 level J:130794
Ldlrtm1Her/Ldlrtm1Her
Pfn1tm1Wit/Pfn1+

(B6.129S-Ldlrtm1Her Pfn1tm1Wit)
impaired macrophage chemotaxis J:140294
Ldlrtm1Her/Ldlrtm1Her
Soat1tm1Far/Soat1tm1Far

(involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J)
skin inflammation J:61147
Ldlrtm1Her/Ldlrtm1Her
Tbx21tm1Glm/Tbx21tm1Glm

(involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6)
abnormal interleukin secretion J:96110
decreased IgG level J:96110
decreased interferon-gamma secretion J:96110
increased IgM level J:96110
Ldlrtm1Her/Ldlrtm1Her
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi

(B6.129-Ldlrtm1Her Tcra-Jtm1Tgi)
decreased interferon-gamma secretion J:140276
Ldlrtm1Her/Ldlrtm1Her
Tg(H2-K-AKR1B1)1Tj/0

(involves: 129S7/SvEvBrd * C57BL/6 * DBA/2)
abnormal macrophage physiology J:100916
Ldlrtm1Her/Ldlrtm1Her
Tlr2tm1Kir/Tlr2tm1Kir

(B6.129-Tlr2tm1Kir Ldlrtm1Her)
abnormal cellular extravasation J:131783
decreased tumor necrosis factor secretion J:131783
Ldlrtm1Her/Ldlrtm1Her
Vwftm1Wgr/Vwftm1Wgr

(B6.129S-Vwftm1Wgr Ldlrtm1Her)
impaired leukocyte tethering or rolling J:106677
Ldlrad3em1Diam/Ldlrad3em1Diam
(C57BL/6-Ldlrad3em1Diam)
decreased susceptibility to Togaviridae infection J:300132
Ldlrad3em1Diam/Ldlrad3em2Diam
(C57BL/6-Ldlrad3em1Diam Ldlrad3em2Diam)
decreased susceptibility to Togaviridae infection J:300132
Ldlrad3em2Diam/Ldlrad3em2Diam
(C57BL/6-Ldlrad3em2Diam)
decreased susceptibility to Togaviridae infection J:300132
Ldlrad4tm1b(EUCOMM)Wtsi/Ldlrad4tm1b(EUCOMM)Wtsi
(C57BL/6N-Ldlrad4tm1b(EUCOMM)Wtsi/Wtsi)
decreased monocyte cell number J:211773
Lect2tm1Ymg/Lect2tm1Ymg
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal cytokine secretion J:90961
abnormal leukocyte physiology J:90961
increased T cell apoptosis J:90961
increased T cell number J:90961
liver inflammation J:90961
Lef1tm1.1(KOMP)Vlcg/Lef1+
(C57BL/6N-Lef1tm1.1(KOMP)Vlcg/Ucd)
increased monocyte cell number J:211773
Lef1tm1Hhx/Lef1tm1Hhx
Tcf7tm1Cle/Tcf7tm1Cle
Gt(ROSA)26Sortm2Sho/Gt(ROSA)26Sor+
Tg(GZMB-cre)1Jcb/0

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N)
abnormal memory T cell physiology J:189838
decreased CD8-positive, alpha-beta T cell number J:189838
decreased tumor necrosis factor secretion J:189838
Lef1tm1Rug/Lef1tm1Rug
(involves: 129S2/SvPas * C57BL/6)
immune system phenotype J:18378
Lefty2tm2Hmd/Lefty2tm2Hmd
(involves: 129P2/OlaHsd * C57BL/6)
accessory spleen J:70483
Lemd2em1(IMPC)Bay/Lemd2+
(C57BL/6N-Lemd2em1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Lepm1Yst/Lepm1Yst
(C57BL/6J-Lepm1Yst)
increased macrophage cell number J:167736
Lepob/Lepob
(involves: C57BL/6J)
abnormal osteoclast differentiation J:60001
Lepob/Lepob
(B6.Cg-Lepob/J)
decreased NK cell number J:117826
lung inflammation J:115772
Lepob/Lepob
(B6.Cg-Lepob/OlaHsd)
abnormal acute inflammation J:124815
abnormal chemokine secretion J:124815
increased interleukin-6 secretion J:124815
increased susceptibility to endotoxin shock J:124815
liver inflammation J:124815
Lepob/Lepob
(involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs)
abnormal microglial cell physiology J:115569
decreased circulating tumor necrosis factor level J:115569
Lepob/Lepob
(involves: C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:164339
decreased splenocyte number J:164339
decreased T cell proliferation J:164339
Lepob/Lepob
(B6.Cg-Lepob/JRj)
liver inflammation J:277927
Lepob/Lepob
Serpine1tm1Mlg/Serpine1tm1Mlg

(involves: 129S2/SvPas * C57BL/6)
abnormal tumor necrosis factor level J:70695
Leptm1b(EUCOMM)Hmgu/Leptm1b(EUCOMM)Hmgu
(C57BL/6N-Leptm1b(EUCOMM)Hmgu/Bay)
decreased spleen weight J:211773
Leprdb-5J/Leprdb-5J
(NOD/ShiLt-Leprdb-5J)
abnormal CD4-positive, alpha beta T cell morphology J:118304
abnormal CD8-positive, alpha beta T cell morphology J:118304
pancreas inflammation J:118305
periinsulitis J:118305
Leprdb-lb/Leprdb-lb
(C57BL/6NCrl-Leprdb-lb/Crl)
white adipose tissue inflammation J:171755
Leprdb-Pas/Leprdb-Pas
(involves: DW/Pas)
enlarged spleen J:174584
Leprdb/Leprdb
(involves: C57BLKS/J)
increased susceptibility to autoimmune diabetes J:7005
Leprdb/Leprdb
(B6.Cg-Dock7m +/+ Leprdb/J)
abnormal chemokine level J:115772
abnormal interleukin level J:115772
abnormal leukocyte morphology J:115772
decreased leukocyte cell number J:115772
increased circulating interleukin-6 level J:115772
increased neutrophil cell number J:115772
lung inflammation J:115772
Leprdb/Leprdb
(BKS.Cg-Dock7m +/+ Leprdb/OlaHsd)
abnormal acute inflammation J:124815
abnormal chemokine secretion J:124815
increased interleukin-6 secretion J:124815
increased susceptibility to endotoxin shock J:124815
liver inflammation J:124815
Leprdb/Leprdb
(involves: C57BL/6)
abnormal osteoclast differentiation J:60001
Leprdb/Leprdb
(B6.BKS(D)-Leprdb/JOrlRj)
liver inflammation J:277927
Leprdb/Leprdb
(BKS.Cg-Dock7m +/+ Leprdb)
kidney inflammation J:346348
Leprm7Btlr/Leprm7Btlr
(C57BL/6J-Leprm7Btlr)
decreased response to antigen J:236685
increased IgE level J:236685
Leprm8Btlr/Leprm8Btlr
(C57BL/6J-Leprm8Btlr)
decreased CD8-positive, naive alpha-beta T cell number J:267679
increased effector memory CD4-positive, alpha-beta T cell number J:267679
increased effector memory CD8-positive, alpha-beta T cell number J:267679
Leprtm1.1Rll/Lepr+
(129P3/J-Leprtm1.1Rll)
increased susceptibility to parasitic infection J:172012
Leprtm1.1Rll/Leprtm1.1Rll
(129P3/J-Leprtm1.1Rll)
increased susceptibility to parasitic infection J:172012
Leprtm1b(EUCOMM)Wtsi/Leprtm1b(EUCOMM)Wtsi
(C57BL/6N-Leprtm1b(EUCOMM)Wtsi/H)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased spleen weight J:211773
increased eosinophil cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Leprtm4Mgmj/Leprtm4Mgmj
(B6.Cg-Leprtm4Mgmj)
decreased CD4-positive, alpha-beta T cell number J:164339
decreased splenocyte number J:164339
decreased T cell proliferation J:164339
Lgals1tm1Rob/Lgals1tm1Rob
(involves: 129S/SvEv)
increased interferon-gamma secretion J:123416
increased interleukin-2 secretion J:123416
increased susceptibility to experimental autoimmune encephalomyelitis J:123416
Lgals1tm1Rob/Lgals1tm1Rob
(involves: 129S/SvEv * 129S1/SvImJ * DBA/2J)
abnormal cytokine secretion J:130208
Lgals2tm1.1Cfg/Lgals2tm1.1Cfg
(involves: C57BL/6)
abnormal immune system physiology J:217719
decreased neutrophil cell number J:217719
enhanced humoral immune response J:217719
increased CD4-positive, alpha-beta T cell number J:217719
increased CD8-positive, alpha-beta T cell number J:217719
increased IgG2b level J:217719
increased IgG3 level J:217719
increased leukocyte cell number J:217719
increased lymphocyte cell number J:217719
increased spleen red pulp amount J:217719
increased susceptibility to type IV hypersensitivity reaction J:217719
increased T cell number J:217719
Lgals3tm1Ftl/Lgals3tm1Ftl
(B6.129S2-Lgals3tm1Ftl)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:109126
abnormal dendritic cell physiology J:109126
abnormal interferon secretion J:109126
abnormal response to infection J:109126
brain inflammation J:109126
decreased macrophage cell number J:109126
increased IgG level J:109126
increased interleukin-12b secretion J:109126
increased susceptibility to parasitic infection J:109126
lung inflammation J:109126
small intestinal inflammation J:109126
Lgals3tm1Ftl/Lgals3tm1Ftl
(involves: 129S2/SvPas * C57BL/6)
abnormal leukocyte physiology J:60741
abnormal macrophage physiology J:60741
abnormal monocyte morphology J:60741
decreased lymphocyte cell number J:60741
decreased macrophage cell number J:313172, J:60741
decreased monocyte cell number J:60741
increased eosinophil cell number J:60741
increased macrophage apoptosis J:60741
peritoneal inflammation J:60741
Lgals3tm1Ftl/Lgals3tm1Ftl
(involves: 129S2/SvPas * CD-1)
liver inflammation J:221030
Lgals3tm1Poi/Lgals3tm1Poi
(involves: 129/Sv * C57BL/6 * SJL)
abnormal macrophage physiology J:131971
impaired macrophage chemotaxis J:131971
impaired macrophage phagocytosis J:131407
impaired neutrophil recruitment J:131407
increased interleukin-6 secretion J:131407
increased susceptibility to bacterial infection J:131407
increased tumor necrosis factor secretion J:131407
lung inflammation J:131407
sepsis J:131407
Lgals3tm1Poi/Lgals3tm1Poi
(involves: 129/Sv * C57BL/6 * MF1 * SJL)
decreased granulocyte number J:110422
Lgals3bptm1Megt/Lgals3bptm1Megt
(involves: 129P2/OlaHsd * C57BL/Ka)
increased circulating interferon-gamma level J:94936
increased circulating interleukin-12 level J:94936
increased susceptibility to endotoxin shock J:94936
increased tumor necrosis factor secretion J:94936
Lgals8tm1(KOMP)Vlcg/Lgals8tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal lymphangiogenesis J:235778
decreased susceptibility to Herpesvirales infection J:235778
Lgals9tm1.1Cfg/Lgals9tm1.1Cfg
(involves: C57BL/6)
abnormal lymph node germinal center morphology J:217719
abnormal Peyer's patch morphology J:217719
enhanced humoral immune response J:217719
increased B cell proliferation J:217719
increased lymphocyte cell number J:217719
increased neutrophil cell number J:217719
increased spleen germinal center size J:217719
lymph node hyperplasia J:217719
spleen hyperplasia J:217719
thymus hyperplasia J:217719
Lgals9tm1Glp/Lgals9tm1Glp
(B6.129S6-Lgals9tm1Glp)
decreased regulatory T cell number J:132889
increased susceptibility to induced arthritis J:132889
increased T-helper 1 cell number J:132889
Lgi3em1(IMPC)Mbp/Lgi3em1(IMPC)Mbp
(C57BL/6N-Lgi3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Lgmntm1Cptr/Lgmntm1Cptr
(B6.129S6-Lgmntm1Cptr)
abnormal adaptive immunity J:155339
decreased interleukin-6 secretion J:155339
decreased interleukin-12b secretion J:155339
decreased tumor necrosis factor secretion J:155339
enlarged spleen J:172774
Lgmntm1Ihn/Lgmntm1Ihn
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:143886
abnormal NK cell physiology J:143886
abnormal spleen morphology J:143886
immune system phenotype J:143886
increased circulating tumor necrosis factor level J:143886
increased lymphocyte cell number J:143886
increased spleen weight J:143886
lgr/lgr
(Not Specified)
eye inflammation J:13879
Lgr4Gt(LST020)Byg/Lgr4Gt(LST020)Byg
(involves: 129P2/OlaHsd * C57BL/6)
increased incidence of corneal inflammation J:134299
Lgr5em1(IMPC)Kmpc/Lgr5+
(C57BL/6NTac-Lgr5em1(IMPC)Kmpc/Kmpc)
increased CD4-negative, CD25-positive NK T cell number J:211773
increased CD8-positive, CD25-positive alpha-beta T cell number J:211773
increased CD11b-high dendritic cell number J:211773
Lgr6em1(IMPC)Ccpcz/Lgr6em1(IMPC)Ccpcz
(C57BL/6NCrl-Lgr6em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased lymphocyte cell number J:211773
Lhcgrtm1(KOMP)Vlcg/Lhcgrtm1(KOMP)Vlcg
(C57BL/6N-Lhcgrtm1(KOMP)Vlcg/Nju)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
small spleen J:211773
small thymus J:211773
Lhcgrtm1Hht/Lhcgrtm1Hht
(involves: 129S7/SvEvBrd * C57BL/6J)
enlarged spleen J:105533
epididymis inflammation J:105533
prostate gland inflammation J:105533
reproductive system inflammation J:105533
Lhx5em1(IMPC)Ccpcz/Lhx5+
(C57BL/6N-Lhx5em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased leukocyte cell number J:211773
Liftm1Cgre/Liftm1Cgre
(involves: MF1)
abnormal macrophage morphology J:96965
increased eosinophil cell number J:96965
increased uterine NK cell number J:96965
Liftm1Phb/Lif+
(involves: 129S2/SvPas * C57BL/6 * DBA/2)
decreased T cell proliferation J:77410
Liftm1Phb/Liftm1Phb
(involves: 129S2/SvPas * C57BL/6 * DBA/2)
decreased T cell proliferation J:77410
Liftm1Stw/Liftm1Stw
(involves: 129S1/Sv * C57BL/6)
increased acute inflammation J:119777
increased circulating interleukin-1 beta level J:119777
Liftm1Stw/Liftm1Stw
(involves: 129S1/Sv * BALB/c)
decreased interleukin-10 secretion J:136940
decreased leukocyte cell number J:136940
increased circulating interleukin-6 level J:136940
increased circulating serum amyloid protein level J:136940
increased circulating tumor necrosis factor level J:136940
increased susceptibility to bacterial infection induced morbidity/mortality J:136940
increased susceptibility to endotoxin shock J:136940
Liftm1Stw/Liftm1Stw
(involves: 129S1/Sv * MF1)
abnormal osteoclast differentiation J:137646
abnormal osteoclast morphology J:137646
abnormal osteoclast physiology J:137646
increased osteoclast cell number J:137646
Lifrtm1Imx/Lifrtm1Imx
(involves: 129P3/J * 129S7/SvEvBrd * C57BL/6)
increased osteoclast cell number J:25253
Lig1tm1Dwm/Lig1tm1Dwm
(involves: 129P2/OlaHsd)
enlarged spleen J:75962
Lig1tm3Dwm/Lig1tm3Dwm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen physiology J:77902
abnormal thymus physiology J:77902
enlarged spleen J:77902
Lig4m1Btlr/Lig4m1Btlr
(C57BL/6J-Lig4m1Btlr)
decreased B cell number J:267684
decreased CD4-positive, alpha-beta T cell number J:267684
decreased CD8-positive, naive alpha-beta T cell number J:267684
decreased IgD level J:267684
decreased IgG level J:267684
impaired humoral immune response J:267684
increased CD8-positive, alpha-beta T cell number J:267684
increased central memory CD8 positive, alpha-beta T cell number J:267684
increased effector memory CD4-positive, alpha-beta T cell number J:267684
increased NK cell number J:267684
Lig4m2Btlr/Lig4m2Btlr
(C57BL/6J-Lig4m2Btlr)
decreased CD4-positive, alpha-beta T cell number J:267692
increased effector memory CD4-positive, alpha-beta T cell number J:267692
Lig4tiny/Lig4tiny
(C57BL/6-Lig4tiny)
absent CD8-positive, alpha-beta T cells J:104190
decreased B cell number J:122725
decreased lymphocyte cell number J:122725
Lig4tm1Fwa/Lig4tm1Fwa
(involves: 129S6/SvEvTac * C57BL/6)
abnormal B cell differentiation J:50865
abnormal lymphopoiesis J:50865
abnormal T cell differentiation J:63078
arrested B cell differentiation J:63078
arrested T cell differentiation J:50865
decreased thymocyte number J:63078
small thymus J:50865
Lig4tm1Fwa/Lig4tm1Fwa
Tg(Cr2-cre)3Cgn/0
Xrcc4tm2Fwa/Xrcc4tm2Fwa

(involves: 129S6/SvEvTac)
abnormal class switch recombination J:126758
Lig4tm1Fwa/Lig4tm1Fwa
Trp53tm1Brd/Trp53tm1Brd

(involves: 129S6/SvEvTac * 129S7/SvEvBrd)
decreased thymocyte number J:63078
increased B cell number J:63078
Lig4tm2.1Fwa/Lig4tm2.1Fwa
(involves: 129S6/SvEvTac)
abnormal B cell activation J:157574
abnormal B cell differentiation J:157574
abnormal immune system cell morphology J:157574
abnormal immune system morphology J:157574
abnormal immune system organ morphology J:157574
abnormal immune system physiology J:157574
abnormal lymphocyte cell number J:157574
abnormal regulatory T cell morphology J:157574
abnormal T cell activation J:157574
abnormal T cell differentiation J:157574
abnormal T cell receptor beta chain V(D)J recombination J:157574
abnormal T cell receptor V(D)J recombination J:157574
abnormal thymus morphology J:157574
decreased B cell number J:157574
decreased CD4-positive, alpha-beta T cell number J:157574
decreased CD8-positive, alpha-beta T cell number J:157574
decreased double-negative T cell number J:157574
decreased double-positive T cell number J:157574
decreased IgA level J:157574
decreased IgG2b level J:157574
decreased IgG3 level J:157574
decreased IgG level J:157574
decreased IgM level J:157574
decreased immunoglobulin level J:157574
decreased interferon-gamma secretion J:157574
decreased interleukin-13 secretion J:157574
decreased spleen weight J:157574
decreased splenocyte number J:157574
decreased T cell proliferation J:157574
decreased thymocyte number J:157574
decreased thymus weight J:157574
increased anti-chromatin antibody level J:157574
increased anti-double stranded DNA antibody level J:157574
increased T cell apoptosis J:157574
intestinal inflammation J:157574
liver inflammation J:157574
small spleen J:157574
small thymus J:157574
Lig4tm3.1Fwa/Lig4tm3.1Fwa
Tg(Cr2-cre)3Cgn/0

(Not Specified)
abnormal class switch recombination J:157537
Lilrb4atm1Eol/Lilrb4atm1Eol
(B6.129P2-Lilrb4atm1Eol)
abnormal cellular extravasation J:129969
abnormal cytokine level J:129969
abnormal immune system cell morphology J:129969
abnormal immune system physiology J:129969
abnormal interferon level J:129969
abnormal interleukin level J:129969
abnormal leukocyte physiology J:129969
decreased IgE level J:129969
increased inflammatory response J:129969
increased macrophage cell number J:129969
increased mast cell degranulation J:129969
increased plasma cell number J:129969
Lilrb4atm1Hrk/Lilrb4atm1Hrk
(involves: 129/Sv * BALB/c)
abnormal mast cell physiology J:70491
increased mast cell degranulation J:70491
increased susceptibility to type I hypersensitivity reaction J:70491
Lilrb4atm1Ttk/Lilrb4atm1Ttk
(B6.129X1-Lilrb4atm1Ttk)
abnormal dendritic cell antigen presentation J:141234
increased susceptibility to graft versus host disease J:141234
Limd1em1(IMPC)H/Limd1em1(IMPC)H
(C57BL/6NTac-Limd1em1(IMPC)H/H)
increased basophil cell number J:211773
Limd1tm1Gdl/Limd1tm1Gdl
(involves: 129X1/SvJ)
abnormal macrophage physiology J:118130
abnormal osteoclast cell number J:118130
abnormal osteoclast physiology J:118130
Lime1tm1.1Mal/Lime1tm1.1Mal
(involves: 129S2/SvPas * C57BL/6)
immune system phenotype J:126321
Lime1tm1.1Mal/Lime1tm1.1Mal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?

(B6.Cg-Rag2tm1Fwa Lime1tm1.1Mal Tg(TcraH-Y,TcrbH-Y)1Pas)
abnormal CD4-positive T cell differentiation J:126321
increased CD4-positive, alpha-beta T cell number J:126321
Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
increased incidence of corneal inflammation J:192231
Limk2whe/Limk2whe
(B6.Cg-Lepob Limk2whe/GrsrJ)
increased incidence of corneal inflammation J:127016
Lipatm1c(EUCOMM)Hmgu/Lipatm1c(EUCOMM)Hmgu
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1Tg(Alb-cre)21Mgn

(involves: C57BL/6J * C57BL/6N * C57BL/6NTac)
liver inflammation J:270182
Lipatm1Ggb/Lipatm1Ggb
(involves: 129P2/OlaHsd * CF-1)
abnormal alveolar macrophage morphology J:101217
abnormal Kupffer cell morphology J:68812
abnormal spleen morphology J:49674, J:68812
chronic inflammation J:101217
enlarged mesenteric lymph nodes J:68812
enlarged spleen J:68812
hepatosplenomegaly J:68812
increased spleen weight J:49674, J:68812
lung inflammation J:101217
Lipt1em1(IMPC)Bay/Lipt1+
(C57BL/6N-Lipt1em1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Listr1BALB/cByJ/?
(involves: BALB/cByJ * C57BL/6ByJ)
decreased susceptibility to bacterial infection J:68879
Listr1BALB/cByJ/?
Listr2C57BL/6ByJ/?

(involves: BALB/cByJ * C57BL/6ByJ)
decreased susceptibility to bacterial infection J:68879
Listr2C57BL/6ByJ/?
(involves: BALB/cByJ * C57BL/6ByJ)
decreased susceptibility to bacterial infection J:68879
Litaftm1.1Ics/Litaftm1.1Ics
(Not Specified)
impaired macrophage chemotaxis J:186411
increased macrophage cell number J:186411
Litaftm1Samr/Litaftm1Samr
(involves: 129S4/SvJae)
abnormal cytokine secretion J:113750
decreased susceptibility to endotoxin shock J:113750
ll/ll
X/Yaa

(BXSB/MpJScr-ll)
abnormal monocyte morphology J:10973
decreased anti-nuclear antigen antibody level J:10973
decreased CD4-positive, alpha-beta T cell number J:10973
decreased IgG level J:10973
decreased susceptibility to autoimmune disorder J:10973
Lmb1C57BL/6Scr/Lmb1C57BL/6Scr
(involves: C57BL/6-Faslpr * MRL-Faslpr)
enlarged lymph nodes J:45708
enlarged spleen J:45708
increased anti-double stranded DNA antibody level J:45708
Lmb1C57BL/6Scr/Lmb1C57BL/6Scr
(MRL.Cg-Lmb1C57BL/6Scr Faslpr)
increased CD8-positive, alpha-beta T cell number J:125557
increased double-negative T cell number J:125557
increased spleen weight J:125557
Lmb1C57BL/6Scr/Lmb1MRL/MpScr
(involves: C57BL/6-Faslpr * MRL-Faslpr)
enlarged lymph nodes J:45708
enlarged spleen J:45708
increased anti-double stranded DNA antibody level J:45708
Lmb1MRL/MpScr/Lmb1MRL/MpScr
(B6.MRL-Lmb1MRL/MpScr Faslpr)
enlarged lymph nodes J:125557
Lmb2C57BL/6Scr/Lmb2MRL/MpScr
(involves: C57BL/6-Faslpr * MRL-Faslpr)
enlarged lymph nodes J:45708
enlarged spleen J:45708
increased anti-double stranded DNA antibody level J:45708
Lmb2MRL/MpScr/Lmb2MRL/MpScr
(involves: C57BL/6-Faslpr * MRL-Faslpr)
enlarged lymph nodes J:45708
enlarged spleen J:45708
increased anti-double stranded DNA antibody level J:45708
Lmb2MRL/MpScr/Lmb2MRL/MpScr
(B6.MRL-Lmb2MRL/MpScr Faslpr)
decreased double-negative T cell number J:125557
Lmb4MRL/MpScr/Lmb4MRL/MpScr
(involves: C57BL/6-Faslpr * MRL-Faslpr)
enlarged lymph nodes J:45708
enlarged spleen J:45708
Lmb4MRL/MpScr/Lmb4MRL/MpScr
(B6.MRL-Lmb4MRL/MpScr Faslpr)
enlarged lymph nodes J:125557
Lmbr1lem1Btlr/Lmbr1lem1Btlr
(C57BL/6J-Lmbr1lem1Btlr)
abnormal alpha-beta T cell morphology J:274568
abnormal B cell differentiation J:274568
abnormal cytotoxic T cell physiology J:274568
abnormal lymphocyte morphology J:274568
decreased CD4-positive, alpha-beta T cell number J:274568
decreased IgD level J:274568
decreased IgG level J:274568
decreased IgM level J:274568
decreased leukocyte cell number J:274568
decreased lymphocyte cell number J:274568
decreased monocyte cell number J:274568
decreased T cell number J:274568
impaired humoral immune response J:274568
impaired natural killer cell mediated cytotoxicity J:274568
increased IgM level J:274568
Lmbr1lm1Btlr/Lmbr1lm1Btlr
(C57BL/6J-Lmbr1lm1Btlr)
abnormal CD4-positive T cell differentiation J:274568
abnormal CD8-positive, alpha-beta T cell differentiation J:274568
abnormal cytotoxic T cell physiology J:274568
abnormal T cell differentiation J:274568
decreased CD4-positive, alpha-beta T cell number J:274568
decreased CD8-positive, alpha-beta T cell number J:274568
decreased CD8-positive, naive alpha-beta T cell number J:274568
decreased dendritic cell number J:274568
decreased IgE level J:274568
decreased IgG level J:274568
decreased IgM level J:274568
decreased NK cell number J:274568
decreased NK T cell number J:274568
decreased T cell number J:274568
impaired humoral immune response J:274568
impaired natural killer cell mediated cytotoxicity J:274568
increased B-1 B cell number J:274568
increased central memory CD8 positive, alpha-beta T cell number J:274568
increased effector memory CD4-positive, alpha-beta T cell number J:274568
increased macrophage cell number J:274568
increased neutrophil cell number J:274568
Lmbr1lm2Btlr/Lmbr1lm2Btlr
(C57BL/6J-Lmbr1lm2Btlr)
increased central memory CD4-positive, alpha-beta T cell number J:274857
LmnaDhe/Lmna+
(B6(D2)-LmnaDhe/TyGrsrJ)
abnormal peritoneal macrophage morphology J:188496
increased susceptibility to otitis media J:188496
Lmnatm1.1Otin/Lmnatm1.1Otin
(involves: 129P2/OlaHsd * C57BL/6)
small spleen J:177632
small thymus J:177632
Lmnatm1.1Otin/Lmnatm1.1Otin
(involves: 129P2/OlaHsd * C57BL/6NTac)
keratoconjunctivitis sicca J:261974
Lmnatm1Stw/Lmnatm1Stw
(involves: 129S1/Sv)
small spleen J:58702
thymus atrophy J:58702
Lmo2tm2(cre)Thr/Lmo2+
(involves: 129P2/OlaHsd * C57BL/6)
decreased granulocyte number J:155870
decreased monocyte cell number J:155870
Lmo2tm2(cre)Thr/Lmo2+
Kmt2atm1Thr/Kmt2a+
Mllt1tm1Thr/Mllt1+

(involves: 129S/SvEv)
abnormal spleen red pulp morphology J:100794
abnormal spleen white pulp morphology J:100794
enlarged spleen J:84518, J:100794
Lmo2tm3Thr/Lmo2tm4Thr
Cd19tm1(cre)Thr/Cd19+

(involves: 129S/SvEv)
immune system phenotype J:86869
Lmo2tm3Thr/Lmo2tm4Thr
Rag1tm1(cre)Thr/Rag1+

(involves: 129S/SvEv)
immune system phenotype J:86869
Lmo2tm3Thr/Lmo2tm4Thr
Tg(Lck-cre)1Thr/0

(involves: 129S/SvEv)
immune system phenotype J:86869
Lmo4tm1Slp/Lmo4tm1Slp
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S1/Sv * C57BL/6 * C57BL/10 * CBA/Ca)
abnormal acute inflammation J:282740
abnormal gut-associated lymphoid tissue morphology J:282740
abnormal lymphocyte physiology J:282740
abnormal lymphopoiesis J:282740
decreased Peyer's patch number J:282740
increased susceptibility to bacterial infection J:282740
Lmo4tm1Slp/Lmo4tm1Slp
Yeats4em1Zfa/Yeats4em1Zfa
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S1/Sv * C57BL/6 * C57BL/10 * CBA/Ca)
abnormal acute inflammation J:282740
abnormal lymphocyte physiology J:282740
abnormal lymphopoiesis J:282740
increased susceptibility to bacterial infection J:282740
Lmod3em1(IMPC)Mbp/Lmod3+
(C57BL/6N-Lmod3em1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Lmod3em1(IMPC)Mbp/Lmod3em1(IMPC)Mbp
(C57BL/6N-Lmod3em1(IMPC)Mbp/Ucd)
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased neutrophil cell number J:211773
Lmr1BALB/c/Lmr1BALB/c
(involves: BALB/c * C57BL/6J)
increased susceptibility to parasitic infection J:40874
Lmr1BALB/c/Lmr1BALB/c
Lmr30C57BL/6/Lmr30BALB/c

(involves: BALB/c * C57BL/6)
increased susceptibility to parasitic infection J:57691
Lmr1BALB/c/Lmr1BALB/c
Lmr30C57BL/6/Lmr30C57BL/6

(involves: BALB/c * C57BL/6)
increased susceptibility to parasitic infection J:57691
Lmr1BALB/c/Lmr1C57BL/6J
(involves: BALB/c * C57BL/6J)
decreased susceptibility to parasitic infection J:40874
Lmr1C57BL/6J/Lmr1C57BL/6J
(involves: BALB/c * C57BL/6J)
decreased susceptibility to parasitic infection J:40874
Lmr2BALB/c/Lmr2BALB/c
(involves: BALB/c * C57BL/6J)
increased susceptibility to parasitic infection J:40874
Lmr2BALB/c/Lmr2C57BL/6J
(involves: BALB/c * C57BL/6J)
decreased susceptibility to parasitic infection J:40874
Lmr2C57BL/6J/Lmr2C57BL/6J
(involves: BALB/c * C57BL/6J)
decreased susceptibility to parasitic infection J:40874
Lmr3BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
abnormal tumor necrosis factor level J:82715
enlarged spleen J:82715
increased IgE level J:82715
Lmr3BALB/cHeA/Lmr3BALB/cHeA
(involves: BALB/cHeA * STS/A)
spleen hyperplasia J:108764
Lmr3BALB/cHeA/Lmr3CcS5/Dem
(involves: BALB/cHeA * STS/A)
spleen hyperplasia J:108764
Lmr4BALB/cHeA/?
Lmr5BALB/cHeA/?

(involves: BALB/cHeA * STS/A)
abnormal tumor necrosis factor level J:82715
Lmr5BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
abnormal interleukin level J:82715
abnormal tumor necrosis factor level J:82715
increased IgE level J:82715
Lmr5CcS5/Dem/Lmr5CcS5/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interleukin-12 level J:108764
Lmr7BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
decreased splenocyte proliferation J:108764
Lmr7CcS5/Dem/?
(involves: BALB/cHeA * STS/A)
spleen hyperplasia J:82715
Lmr8BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
increased IgE level J:82717
Lmr8BALB/cHeA/Lmr8BALB/cHeA
(involves: BALB/cHeA * STS/A)
spleen hyperplasia J:108764
Lmr8BALB/cHeA/Lmr8CcS20/Dem
(involves: BALB/cHeA * STS/A)
spleen hyperplasia J:108764
Lmr9BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
increased IgE level J:82717
Lmr9BALB/cHeA/Lmr9CcS20/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interleukin-6 level J:108764
Lmr9CcS20/Dem/?
(involves: BALB/cHeA * STS/A)
decreased IgE level J:82717
Lmr9CcS20/Dem/Lmr9CcS20/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interleukin-6 level J:108764
Lmr10BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
increased IgE level J:82717
Lmr10CcS20/Dem/?
(involves: BALB/cHeA * STS/A)
decreased IgE level J:82717
Lmr11BALB/cHeA/Lmr11BALB/cHeA
Lmr8CcS20/Dem/Lmr8CcS20/Dem

(involves: BALB/cHeA * STS/A)
decreased IgE level J:82717
Lmr11BALB/cHeA/Lmr11CcS20/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interleukin-6 level J:108764
Lmr11CcS20/Dem/Lmr11CcS20/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interleukin-6 level J:108764
Lmr12BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
decreased IgE level J:82717
Lmr12BALB/cHeA/Lmr12BALB/cHeA
Lmr14BALB/cHeA/Lmr14BALB/cHeA

(involves: BALB/cHeA * STS/A)
increased circulating tumor necrosis factor level J:108764
Lmr12BALB/cHeA/Lmr12CcS16/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interleukin-4 level J:108764
Lmr12CcS16/Dem/?
(involves: BALB/cHeA * STS/A)
increased IgE level J:82717
Lmr12CcS16/Dem/Lmr12CcS16/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interleukin-4 level J:108764
Lmr12CcS16/Dem/Lmr12CcS16/Dem
Lmr19BALB/cHeA/Lmr19BALB/cHeA

(involves: BALB/cHeA * STS/A)
spleen hyperplasia J:108764
Lmr13BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
decreased IgE level J:82717
Lmr13CcS16/Dem/Lmr13CcS16/Dem
Lmr14CcS16/Dem/Lmr14CcS16/Dem

(involves: BALB/cHeA * STS/A)
decreased circulating tumor necrosis factor level J:108764
Lmr14BALB/cHeA/?
(involves: BALB/cHeA * STS/A)
spleen hyperplasia J:108764
Lmr14BALB/cHeA/Lmr14BALB/cHeA
Lmr5BALB/cHeA/?

(involves: BALB/cHeA * STS/A)
increased IgE level J:82715
Lmr14BALB/cHeA/Lmr14BALB/cHeA
Lmr5BALB/cHeA/Lmr5BALB/cHeA

(involves: BALB/cHeA * STS/A)
increased IgE level J:82717
Lmr14BALB/cHeA/Lmr14CcS16/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interferon-gamma level J:108764
Lmr14CcS16/Dem/?
(involves: BALB/cHeA * STS/A)
enlarged spleen J:82716
Lmr14CcS16/Dem/Lmr14CcS16/Dem
(involves: BALB/cHeA * STS/A)
increased circulating interferon-gamma level J:108764
Lmr14CcS16/Dem/Lmr14CcS16/Dem
Lmr5BALB/cHeA/?

(involves: BALB/cHeA * STS/A)
increased IgE level J:82715
Lmr14CcS16/Dem/Lmr14CcS16/Dem
Lmr5BALB/cHeA/Lmr5BALB/cHeA

(involves: BALB/cHeA * STS/A)
increased IgE level J:82717
Lmr14CcS16/Dem/Lmr14CcS16/Dem
Lmr5CcS5/Dem/Lmr5CcS5/Dem

(involves: BALB/cHeA * STS/A)
increased circulating interleukin-12 level J:108764
Lmr15BALB/cHeA/Lmr15CcS16/Dem
(involves: BALB/cHeA * STS/A)
decreased circulating interferon-gamma level J:108764
Lmr15CcS16/Dem/Lmr15CcS16/Dem
(involves: BALB/cHeA * STS/A)
decreased circulating interferon-gamma level J:108764
Lmr16STS/A/Lmr16STS/A
Lmr18BALB/cHeA/Lmr18BALB/cHeA

(involves: BALB/cHeA * STS/A)
spleen hyperplasia J:108764
Lmr17BALB/cHeA/Lmr17CcS20/Dem
(involves: BALB/cHeA * STS/A)
increased circulating tumor necrosis factor level J:108764
Lmr17CcS20/Dem/Lmr17CcS20/Dem
(involves: BALB/cHeA * STS/A)
increased circulating tumor necrosis factor level J:108764
Lmr17CcS20/Dem/Lmr17CcS20/Dem
Lmr3BALB/cHeA/Lmr3BALB/cHeA

(involves: BALB/cHeA * STS/A)
increased circulating interferon-gamma level J:108764
Lmr18BALB/cHeA/Lmr18BALB/cHeA
(involves: BALB/cHeA * STS/A)
decreased splenocyte proliferation J:108764
Lmr18BALB/cHeA/Lmr18CcS20/Dem
(involves: BALB/cHeA * STS/A)
decreased splenocyte proliferation J:108764
Lmrq1BALB/cAnSim/Lmrq1C57BL/10Sn
(involves: BALB/cAnNSim * C57BL/10J)
decreased susceptibility to parasitic infection J:40624
Lmrq2BALB/cAnSim/Lmrq2C57BL/10Sn
(involves: BALB/cAnNSim * C57BL/10J)
decreased susceptibility to parasitic infection J:40624
Lmrq3BALB/cAnSim/Lmrq3C57BL/10Sn
(involves: BALB/cAnNSim * C57BL/10J)
decreased susceptibility to parasitic infection J:40624
Lmrq4BALB/cAnSim/Lmrq4C57BL/10Sn
(involves: BALB/cAnNSim * C57BL/10J)
decreased susceptibility to parasitic infection J:40624
Lmrq4C57BL/10Sn/Lmrq4C57BL/10Sn
(C.B10-(D11Mit2-D11Mit29))
decreased susceptibility to parasitic infection J:40624
Lmrq5BALB/cAnNSim/Lmrq5C57BL/10Sn
(involves: BALB/cAnNSim * C57BL/10J)
decreased susceptibility to parasitic infection J:40624
Lmrq6BALB/cAnSim/Lmrq6C57BL/10Sn
(involves: BALB/cAnNSim * C57BL/10J)
decreased susceptibility to parasitic infection J:40624
Lncucc1em1Bwu/Lncucc1em1Bwu
(C57BL/6-Lncucc1em1Bwu)
abnormal susceptibility to colitis induced morbidity/mortality J:340220
increased susceptibility to induced colitis J:340220
Lnx1tm1Lex/Lnx1tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased B-1b cell number J:171883
Loricrintm1.1(KOMP)Vlcg/Loricrin+
(C57BL/6N-Loricrintm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Loricrintm1.1(KOMP)Vlcg/Loricrintm1.1(KOMP)Vlcg
(C57BL/6N-Loricrintm1.1(KOMP)Vlcg/Ucd)
increased spleen weight J:211773
Loricrintm1Der/Loricrintm1Der
(FVB.129S7-Loricrintm1Der)
erythroderma J:65187
Loxem1(IMPC)Mbp/Lox+
(C57BL/6N-Loxem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Loxtm1.1Khki/Loxtm1.1Khki
(involves: C57BL/6)
increased lymphocyte cell number J:264295
Loxl2tm1.2Acan/Loxl2tm1.2Acan
(Not Specified)
decreased inflammatory response J:220689
Lpar2tm1Dgen/Lpar2tm1Dgen
(B6.Cg-Lpar2tm1Dgen)
abnormal dendritic cell physiology J:184061
decreased interleukin-10 secretion J:184061
increased IgE level J:184061
increased interleukin-13 secretion J:184061
increased susceptibility to type I hypersensitivity reaction J:184061
increased tumor necrosis factor secretion J:184061
lung inflammation J:184061
Lpar4tm1Sati/Y
(involves: C57BL/6)
lymphangiectasis J:167262
Lpar4tm1Sati/Lpar4tm1Sati
(involves: C57BL/6)
lymphangiectasis J:167262
Lpin2tm1b(KOMP)Wtsi/Lpin2tm1b(KOMP)Wtsi
(C57BL/6N-Lpin2tm1b(KOMP)Wtsi/Tcp)
enlarged lymph nodes J:211773
Lpin2tm1Reue/Lpin2tm1Reue
(involves: C57BL/6J)
immune system phenotype J:189894
Lpin3tm1b(KOMP)Wtsi/Lpin3tm1b(KOMP)Wtsi
(C57BL/6N-Lpin3tm1b(KOMP)Wtsi/Ucd)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Lpn1NZB/Lpn1NZB
(involves: NZB * NZW)
kidney inflammation J:6026
Lpn1NZB/Lpn1NZW
(involves: NZB * NZW)
kidney inflammation J:6026
Lpn2NZB/Lpn2NZW
(involves: NZB * NZW)
kidney inflammation J:6026
Lpn2NZW/Lpn2NZW
(involves: NZB * NZW)
kidney inflammation J:6026
Lpoem1Zlu/Lpoem1Zlu
(involves: C57BL/6 * SJL)
aortitis J:307289
arteritis J:307289
blood vessel inflammation J:307289
cardiovalvulitis J:307289
gallbladder inflammation J:307289
glomerulonephritis J:307289
increased inflammatory response J:307289
intestinal inflammation J:307289
liver inflammation J:307289
lung inflammation J:307289
mastitis J:307289
myocarditis J:307289
myositis J:307289
pancreas inflammation J:307289
stomach inflammation J:307289
Lppl1C57BL/6J/?
(involves: C57BL/6J * DBA/2J)
abnormal leukocyte physiology J:90647
Lprm3MRL/MpJ/Lprm3MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
glomerulonephritis J:44625
Lprm4MRL/MpJ/Lprm4MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
enlarged spleen J:44625
Lprm5MRL/MpJ/Lprm5MRL/MpJ
(involves: C3H/HeJ-Faslpr * MRL/MpJ-Faslpr)
abnormal humoral immune response J:44625
Lptl1DBA/2J/?
(involves: C57BL/6J * DBA/2J)
abnormal tumor necrosis factor level J:90647
Lptl1DBA/2J/Lptl1DBA/2J
Lptl2DBA/2J/Lptl2DBA/2J

(involves: C57BL/6J * DBA/2J)
abnormal tumor necrosis factor level J:90647
Lptl2DBA/2J/?
(involves: C57BL/6J * DBA/2J)
abnormal tumor necrosis factor level J:90647
Lpxntm1b(EUCOMM)Hmgu/Lpxntm1b(EUCOMM)Hmgu
(C57BL/6N-Lpxntm1b(EUCOMM)Hmgu/Wtsi)
abnormal plasma cell differentiation J:305662
decreased IgM level J:305662
immune system phenotype J:305662
Lratd2em1(IMPC)Ccpcz/Lratd2em1(IMPC)Ccpcz
(C57BL/6N-Lratd2em1(IMPC)Ccpcz/Ccpcz)
decreased eosinophil cell number J:211773
increased B-2 B cell number J:211773
Lrbaem1Btlr/Lrbaem1Btlr
(C57BL/6J-Lrbaem1Btlr)
increased susceptibility to induced colitis J:274652
Lrbaem2Btlr/Lrbaem2Btlr
(C57BL/6J-Lrbaem2Btlr)
increased susceptibility to induced colitis J:274652
Lrbaem3Btlr/Lrbaem3Btlr
(C57BL/6J-Lrbaem3Btlr)
increased susceptibility to induced colitis J:274652
LrbaGt(OST69142)Lex/LrbaGt(OST69142)Lex
(involves: 129 * 129S5/SvEvBrd)
abnormal NK cell physiology J:237187
decreased susceptibility to graft versus host disease J:237187
impaired natural killer cell mediated cytotoxicity J:237187
increased length of allograft survival J:237187
increased regulatory T cell number J:237187
Lrbam1Btlr/Lrbam1Btlr
(C57BL/6J-Lrbam1Btlr)
increased susceptibility to induced colitis J:274652
Lrbam2Btlr/Lrbam2Btlr
(C57BL/6J-Lrbam2Btlr)
increased susceptibility to induced colitis J:274652
Lrch1em1Hwa/Lrch1em1Hwa
(Not Specified)
abnormal cellular extravasation J:238772
immune system phenotype J:238772
increased susceptibility to experimental autoimmune encephalomyelitis J:238772
Lrdm1MRL/MpJ/?
(involves: CAST/Ei * MRL/MpJ-Faslpr/J)
kidney inflammation J:3304
Lrdm2MRL/MpJ/?
(involves: CAST/Ei * MRL/MpJ-Faslpr/J)
kidney inflammation J:3304
Lrfn2Tg(CD2-Myb/en)5Kmw/Lrfn2+
(involves: C57BL/10 * CBA)
abnormal lymph node morphology J:125805
decreased T cell number J:126456
decreased T cell proliferation J:126456
Lrfn2Tg(CD2-Myb/en)5Kmw/Lrfn2+
Tg(H2-K-Myc)1Brn/?

(involves: C57BL/10 * CBA * FVB/N)
abnormal lymph node morphology J:125805
enlarged lymph nodes J:125805
enlarged spleen J:125805
lymph node hemorrhage J:125805
lymph node necrosis J:125805
spleen hyperplasia J:125805
Lrfn2Tg(CD2-Myb/en)5Kmw/Lrfn2Tg(CD2-Myb/en)5Kmw
(involves: C57BL/10 * CBA)
abnormal thymus cortex morphology J:126456
abnormal thymus medulla morphology J:126456
decreased CD8-positive, alpha-beta T cell number J:126456
decreased double-negative T cell number J:126456
decreased T cell number J:126456
decreased T cell proliferation J:126456
small spleen J:126456
small thymus J:126456
Lrfn2tm1.1Jaru/Lrfn2tm1.1Jaru
(B6.129P2(Cg)-Lrfn2tm1.1Jaru)
decreased granulocyte number J:301285
decreased leukocyte cell number J:301285
decreased lymphocyte cell number J:301285
Lrig1m1Anu/Lrig1m1Anu
(C57BL/NCrlAnu-Lrig1m1Anu)
immune system phenotype J:104190
Lrig1tm1a(EUCOMM)Wtsi/Lrig1tm1a(EUCOMM)Wtsi
(involves: C57BL/6 * C57BL/6N)
increased susceptibility to bacterial infection J:213427
Lrig2tm1.1Hhed/Lrig2tm1.1Hhed
(involves: 129 * C57BL/6 * FVB/N)
increased inflammatory response J:205929
Lrig3em1(IMPC)Ccpcz/Lrig3em1(IMPC)Ccpcz
(C57BL/6NCrl-Lrig3em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Lrp1tm2Her/Lrp1tm2Her
Tg(Camk2a-cre)T29-1Stl/0

(involves: 129S7/SvEvBrd * BALB/c * C57BL)
brain inflammation J:167724
Lrp2b2b2671Clo/Lrp2b2b2671Clo
(C57BL/6J-Lrp2b2b2671Clo)
thymus hypoplasia J:175213
Lrp5tm1Grw/Lrp5tm1Grw
(involves: 129S1/Sv * 129X1/SvJ)
decreased osteoclast cell number J:104382
Lrp6tm1Arma/Lrp6tm1Arma
(C57BL/6-Lrp6tm1Arma)
liver inflammation J:225450
Lrp12em1Gpt/Lrp12em1Gpt
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * C57BL/6JGpt * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:338432
enhanced leukocyte migration J:338432
immune system phenotype J:338432
increased susceptibility to induced colitis J:338432
increased T cell number J:338432
Lrrc3tm1b(EUCOMM)Hmgu/Lrrc3tm1b(EUCOMM)Hmgu
(C57BL/6N-Lrrc3tm1b(EUCOMM)Hmgu/Ics)
decreased lymphocyte cell number J:211773
Lrrc4ctm1Lex/Lrrc4ctm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased circulating interleukin-6 level J:171883
Lrrc8atm1.1Geha/Lrrc8atm1.1Geha
(B6.129S1(Cg)-Lrrc8atm1.1Geha)
abnormal B cell differentiation J:211308
abnormal T cell differentiation J:211308
abnormal T cell physiology J:211308
abnormal T cell selection J:211308
abnormal thymus apoptosis J:211308
abnormal thymus medulla morphology J:211308
abnormal thymus morphology J:211308
abnormal thymus physiology J:211308
absent thymus corticomedullary boundary J:211308
decreased B cell number J:211308
decreased CD4-positive, alpha-beta T cell number J:211308
decreased CD8-positive, alpha-beta T cell number J:211308
decreased DN2 thymocyte number J:211308
decreased DN3 thymocyte number J:211308
decreased DN4 thymocyte number J:211308
decreased double-negative T cell number J:211308
decreased double-positive T cell number J:211308
decreased immature B cell number J:211308
decreased marginal zone B cell number J:211308
decreased pre-B cell number J:211308
decreased T cell number J:211308
decreased T cell proliferation J:211308
decreased thymocyte number J:211308
decreased transitional stage B cell number J:211308
increased IgG2a level J:211308
increased pro-B cell number J:211308
increased regulatory T cell number J:211308
increased thymocyte apoptosis J:211308
small spleen J:211308
small thymus J:211308
small thymus cortex J:211308
thymus hypoplasia J:211308
Lrrc8bem1Bcgen/Lrrc8bem1Bcgen
(C57BL/6N-Lrrc8bem1Bcgen)
immune system phenotype J:288504
Lrrc8cem1(IMPC)Mbp/Lrrc8cem1(IMPC)Mbp
(C57BL/6N-Lrrc8cem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
Lrrc8dem1Bcgen/Lrrc8dem1Bcgen
(C57BL/6N-Lrrc8dem1Bcgen)
immune system phenotype J:288504
Lrrc8eem1Bcgen/Lrrc8eem1Bcgen
(C57BL/6N-Lrrc8eem1Bcgen)
abnormal circulating cytokine level J:288504
decreased circulating interferon-beta level J:288504
decreased circulating tumor necrosis factor level J:288504
decreased interferon-beta secretion J:288504
increased susceptibility to viral infection J:288504
increased susceptibility to viral infection induced morbidity/mortality J:288504
Lrrc17em1(IMPC)Ccpcz/Lrrc17em1(IMPC)Ccpcz
(C57BL/6N-Lrrc17em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Lrrc17tm1Nik/Lrrc17+
Nf1tm1Par/Nf1tm1Par
Srpk2tm1Nik/Srpk2+
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
increased leukocyte cell number J:161558
Lrrc19tm1Ryag/Lrrc19tm1Ryag
(involves: C57BL/6J * C57BL/6NTac)
decreased circulating interleukin-6 level J:271376
decreased circulating tumor necrosis factor level J:271376
increased susceptibility to bacterial infection J:271376
Lrrc25em1Cya/Lrrc25em1Cya
(C57BL/6J-Lrrc25em1Cya/Cya)
abnormal tumor necrosis factor level J:270157
heart inflammation J:270157
Lrrc30em1(IMPC)Rbrc/Lrrc30em1(IMPC)Rbrc
(C57BL/6NJcl-Lrrc30em1(IMPC)Rbrc/Rbrc)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Lrrc32tm1.1Hfuj/Lrrc32tm1.1Hfuj
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac * DBA/2)
abnormal regulatory T cell physiology J:204761
immune system phenotype J:204761
Lrrc55osem1Caox/Lrrc55osem1Caox
(C57BL/6-Lrrc55osem1Caox)
decreased circulating interferon-beta level J:293325
immune system phenotype J:293325
increased susceptibility to Riboviria infection J:293325
increased susceptibility to Riboviria infection induced morbidity/mortality J:293325
Lrrc56em1(IMPC)Tcp/Lrrc56em1(IMPC)Tcp
(C57BL/6N-Lrrc56em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Lrrk1tm1.1Smo/Lrrk1tm1.1Smo
(involves: 129S/Sv)
abnormal osteoclast physiology J:208677
increased osteoclast cell number J:208677
Lrrk1tm1b(KOMP)Wtsi/Lrrk1tm1b(KOMP)Wtsi
(C57BL/6N-Lrrk1tm1b(KOMP)Wtsi/H)
decreased eosinophil cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
small thymus J:211773
Lrrk2tm1.1Cai/Lrrk2+
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-SNCA*A53T)E2Cai/0

(involves: 129X1/SvJ * C57BL/6)
microgliosis J:156512
Lrrk2tm1.1Cai/Lrrk2tm1.1Cai
(involves: 129X1/SvJ * C57BL/6)
microgliosis J:156512
Lrrk2tm2.1Shn/Lrrk2tm2.1Shn
(involves: 129 * C57BL/6)
kidney inflammation J:160542
Lrrtm2em1(IMPC)Mbp/Lrrtm2em1(IMPC)Mbp
(C57BL/6N-Lrrtm2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Lsm3em1Caox/Lsm3em1Caox
(involves: C57BL/6J)
decreased susceptibility to Orthomyxoviridae infection J:262834
decreased susceptibility to Riboviria infection J:262834
decreased susceptibility to Riboviria infection induced morbidity/mortality J:262834
increased circulating interferon-alpha level J:262834
increased circulating interferon-beta level J:262834
increased circulating interleukin-6 level J:262834
Lsm8em1(IMPC)Mbp/Lsm8+
(C57BL/6N-Lsm8em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Lsm14atm1b(KOMP)Wtsi/Lsm14a+
(C57BL/6N-Lsm14atm1b(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
Lsp1tm1Jejb/Lsp1tm1Jejb
(involves: 129S1/Sv * 129X1/SvJ)
abnormal cellular extravasation J:96022
abnormal immune system morphology J:64219
abnormal leukocyte physiology J:68128
abnormal lymphopoiesis J:64219
impaired neutrophil chemotaxis J:68128
increased macrophage cell number J:64219
Lsr1A/J/?
(involves: A/J * C57BL/6J)
increased susceptibility to bacterial infection J:7345
Lsr1C57BL/6J/?
(involves: A/J * C57BL/6J)
decreased susceptibility to bacterial infection J:7345
Lsstm1b(KOMP)Wtsi/Lss+
(C57BL/6N-Lsstm1b(KOMP)Wtsi/Ieg)
increased leukocyte cell number J:211773
Lst1tm1(KOMP)Vlcg/Lst1tm1(KOMP)Vlcg
(C57BL/6N-Lst1tm1(KOMP)Vlcg)
immune system phenotype J:235700
increased susceptibility to Orthomyxoviridae infection J:235700
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:235700
Lta4htm1Bhk/Lta4htm1Bhk
(involves: 129P2/OlaHsd * 129S/SvEv)
decreased acute inflammation J:58985
decreased susceptibility to type I hypersensitivity reaction J:58985
Lta/Tnftm1Eug/Lta/Tnftm1Eug
(involves: 129)
abnormal humoral immune response J:31129
abnormal spleen marginal zone morphology J:31129
abnormal spleen morphology J:31129
absent lymph nodes J:31129
absent Peyer's patches J:31129
decreased IgA level J:31129
decreased T cell number J:31129
increased B cell number J:31129
increased leukocyte cell number J:31129
increased susceptibility to parasitic infection J:31129
increased susceptibility to Poxviridae infection J:31129
increased susceptibility to Riboviria infection J:31129
Lta/Tnftm1Eug/Lta/Tnftm1Eug
(involves: 129/Sv * C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:115225
decreased susceptibility to parasitic infection J:37696
Lta/Tnftm1Eug/Lta/Tnftm1Eug
(B6.129-Lta/Tnftm1Eug)
decreased circulating interferon-gamma level J:115034
decreased IgG1 level J:115034
decreased IgG2a level J:115034
decreased IgG3 level J:115034
decreased interferon-gamma secretion J:115034
decreased susceptibility to induced arthritis J:115034
impaired macrophage phagocytosis J:115034
increased IgM level J:115034
increased susceptibility to bacterial infection J:115034
increased susceptibility to bacterial infection induced morbidity/mortality J:115034
Lta/Tnftm1Eug/Lta/Tnftm1Eug
(involves: 129 * C57BL/6J)
increased spleen weight J:112797
Lta/Tnftm1Eug/Lta/Tnftm1Eug
(involves: 129)
abnormal humoral immune response J:31129
abnormal spleen marginal zone morphology J:31129
abnormal spleen morphology J:31129
absent lymph nodes J:31129
absent Peyer's patches J:31129
decreased IgA level J:31129
decreased T cell number J:31129
increased B cell number J:31129
increased leukocyte cell number J:31129
increased susceptibility to bacterial infection J:31129
increased susceptibility to Poxviridae infection J:31129
increased susceptibility to Riboviria infection J:31129
Lta/Tnftm1Eug/Lta/Tnftm1Eug
(involves: 129/Sv * C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:115225
decreased susceptibility to parasitic infection J:37696
Lta/Tnftm1Eug/Lta/Tnftm1Eug
(B6.129-Lta/Tnftm1Eug)
decreased circulating interferon-gamma level J:115034
decreased IgG1 level J:115034
decreased IgG2a level J:115034
decreased IgG3 level J:115034
decreased interferon-gamma secretion J:115034
decreased susceptibility to induced arthritis J:115034
impaired macrophage phagocytosis J:115034
increased IgM level J:115034
increased susceptibility to bacterial infection J:115034
increased susceptibility to bacterial infection induced morbidity/mortality J:115034
Lta/Tnftm1Eug/Lta/Tnftm1Eug
(involves: 129 * C57BL/6J)
increased spleen weight J:112797
Lta/Tnftm1Fda/Lta/Tnftm1Fda
(involves: 129S1/Sv * 129X1/SvJ)
decreased susceptibility to endotoxin shock J:39519
decreased tumor necrosis factor secretion J:39519
increased susceptibility to bacterial infection J:39519
Lta/Tnftm1Fda/Lta+
(involves: 129S1/Sv * 129X1/SvJ)
decreased susceptibility to endotoxin shock J:39519
decreased tumor necrosis factor secretion J:39519
increased susceptibility to bacterial infection J:39519
Lta/Tnftm1Fda/Lta/Tnftm1Fda
(involves: 129S1/Sv * 129X1/SvJ)
decreased susceptibility to endotoxin shock J:39519
decreased tumor necrosis factor secretion J:39519
increased susceptibility to bacterial infection J:39519
Lta/Tnftm1Fda/Tnf+
(involves: 129S1/Sv * 129X1/SvJ)
decreased susceptibility to endotoxin shock J:39519
decreased tumor necrosis factor secretion J:39519
increased susceptibility to bacterial infection J:39519
Lta/Tnftm1Jods/Lta/Tnftm1Jods
(C57BL/6J-Lta/Tnftm1Jods)
abnormal spleen morphology J:43602
abnormal spleen white pulp morphology J:43602
absent lymph nodes J:43602
absent Peyer's patches J:43602
decreased immunoglobulin level J:43602
enlarged spleen J:43602
increased leukocyte cell number J:43602
Lta/Tnftm1Jods/Lta/Tnftm1Jods
(C57BL/6-Lta/Tnftm1Jods)
abnormal spleen white pulp morphology J:78229
decreased susceptibility to experimental autoimmune encephalomyelitis J:47428
Lta/Tnftm1Jods/Lta/Tnftm1Jods
(involves: C57BL/6)
abnormal gamma-delta T cell morphology J:169863
Lta/Tnftm1Jods/Lta/Tnftm1Jods
(C57BL/6J-Lta/Tnftm1Jods)
abnormal spleen morphology J:43602
absent lymph nodes J:43602
absent Peyer's patches J:43602
decreased immunoglobulin level J:43602
enlarged spleen J:43602
increased leukocyte cell number J:43602
Lta/Tnftm1Jods/Lta/Tnftm1Jods
(C57BL/6-Lta/Tnftm1Jods)
abnormal spleen white pulp morphology J:78229
decreased susceptibility to experimental autoimmune encephalomyelitis J:47428
Lta/Tnftm1Jods/Lta/Tnftm1Jods
(involves: C57BL/6)
abnormal gamma-delta T cell morphology J:169863
Ltahlb382/Ltahlb382
(C57BL/6J-Ltahlb382/J)
abnormal immune system organ morphology J:134498
absent lymph nodes J:134498
absent marginal zone B cells J:134498
absent mesenteric lymph nodes J:134498
absent Peyer's patches J:134498
absent spleen germinal center J:134498
absent spleen marginal zone J:134498
decreased NK cell number J:134498
decreased transitional stage B cell number J:134498
increased B-1b cell number J:134498
increased leukocyte cell number J:82961
liver inflammation J:134498
lung inflammation J:134498
Ltatm1.1(KOMP)Vlcg/Ltatm1.1(KOMP)Vlcg
(C57BL/6N-Ltatm1.1(KOMP)Vlcg/Ucd)
decreased monocyte cell number J:211773
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Ltatm1.1Sned/Ltatm1.1Sned
(B6.129-Ltatm1.1Sned)
abnormal circulating tumor necrosis factor level J:109621
abnormal class switch recombination J:109621
abnormal humoral immune response J:109621
abnormal immune system morphology J:109621
abnormal lymphopoiesis J:109621
absent Peyer's patches J:109621
decreased spleen white pulp amount J:109621
enlarged spleen J:109621
increased susceptibility to bacterial infection induced morbidity/mortality J:109621
Ltatm1Dch/Ltatm1Dch
(B6.129S2-Ltatm1Dch)
abnormal class switch recombination J:80616
abnormal cytokine secretion J:95222
abnormal immune serum protein physiology J:80616
abnormal mucosa-associated lymphoid tissue morphology J:95222
abnormal spleen morphology J:80616
absent Peyer's patches J:80616
absent spleen germinal center J:80616
absent spleen marginal zone J:80616
decreased IgG level J:80616
decreased spleen B cell follicle number J:80616
decreased spleen white pulp amount J:80616
increased IgM level J:80616
increased leukocyte cell number J:80616
Ltatm1Dch/Ltatm1Dch
(involves: 129S2/SvPas * C57BL/6)
abnormal class switch recombination J:109621
abnormal humoral immune response J:39746
abnormal leukocyte cell number J:17976
abnormal lymph node morphology J:17976
abnormal lymph node primary follicle morphology J:109621
abnormal spleen morphology J:17976, J:39746
abnormal spleen periarteriolar lymphoid sheath morphology J:17976
absent axillary lymph nodes J:17976
absent cervical lymph nodes J:17976
absent inguinal lymph nodes J:17976
absent mesenteric lymph nodes J:17976, J:39746
absent Peyer's patches J:17976
absent popliteal lymph nodes J:17976
absent spleen marginal zone J:17976
decreased interferon-gamma secretion J:109621
decreased spleen white pulp amount J:109621
decreased T cell number J:17976
decreased tumor necrosis factor secretion J:109621
increased B cell number J:17976
increased leukocyte cell number J:17976
Ltatm1Dch/Ltatm1Dch
(B6.129S2-Ltatm1Dch/J)
abnormal lymph organ development J:73100
Ltatm1Dch/Ltatm1Dch
(involves: 129S2/SvPas)
abnormal lymphocyte morphology J:173115
abnormal thymus epithelium morphology J:173115
abnormal thymus medulla morphology J:173115
small thymus medulla J:173115
Ltatm1Dch/Ltatm1Dch
Rorctm2Litt/Rorc+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
abnormal gut-associated lymphoid tissue morphology J:91566
Ltatm1Dch/Ltatm1Dch
Tg(Igk-Lta/Ltb)4Cys/0

(involves: 129S2/SvPas * C57BL/6J * DBA/2J)
abnormal lymph organ development J:73100
abnormal spleen morphology J:73100
immune system phenotype J:73100
Ltatm1Dch/Ltatm1Dch
Tnfsf14tm1Lpc/Tnfsf14tm1Lpc

(involves: 129S2/SvPas * 129X1/SvJ)
abnormal lymphocyte morphology J:173115
abnormal thymus epithelium morphology J:173115
small thymus medulla J:173115
Ltatm1Jods/Ltatm1Jods
(C57BL/6-Ltatm1Jods)
abnormal immune system organ morphology J:47428
abnormal spleen morphology J:47428
abnormal spleen white pulp morphology J:78229
absent peripheral lymph nodes J:47428
absent Peyer's patches J:47428
increased lymphocyte cell number J:47428
Ltatm1Jods/Ltatm1Jods
(involves: C57BL/6)
abnormal thymus epithelium morphology J:125864
Ltatm1Tab/Ltatm1Tab
(either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * CF-1))
abnormal humoral immune response J:28061
absent lymph nodes J:28061
absent Peyer's patches J:28061
absent spleen marginal zone J:28061
decreased IgA level J:28061
decreased spleen white pulp amount J:28061
increased IgM level J:28061
increased leukocyte cell number J:28061
increased spleen weight J:28061
Ltatm1Tab/Ltatm1Tab
(involves: 129S2/SvPas * C57BL/6)
decreased tumor necrosis factor secretion J:109621
Ltatm1Tab/Ltatm1Tab
(B6.129S2-Ltatm1Tab)
decreased susceptibility to parasitic infection J:121070
Ltb4r1tm1Adl/Ltb4r1tm1Adl
(involves: 129S4/SvJae * C57BL/6)
abnormal leukocyte adhesion J:63873
abnormal leukocyte migration J:63873
abnormal macrophage physiology J:63873
abnormal neutrophil physiology J:63873
impaired eosinophil recruitment J:63873
impaired neutrophil chemotaxis J:63873
Ltb4r1tm1Bodd/Ltb4r1tm1Bodd
(involves: 129S4/SvJaeSor * C57BL/6)
decreased susceptibility to autoimmune disorder J:108446
Ltb4r1tm1Bodd/Ltb4r1tm1Bodd
(involves: 129S4/SvJaeSor)
decreased susceptibility to induced arthritis J:131779
Ltb4r1tm1Bodd/Ltb4r1tm1Bodd
(either: (involves: 129S4/SvJaeSor * BALB/c ) or (involves: 129S4/SvJaeSor * C57BL/6))
decreased susceptibility to induced arthritis J:163271
impaired neutrophil chemotaxis J:163271
Ltb4r1tm1Tksh/Ltb4r1tm1Tksh
(B6.Cg-Ltb4r1tm1Tksh)
abnormal cytokine secretion J:118995
decreased eosinophil cell number J:118995
decreased IgE level J:118995
decreased susceptibility to type I hypersensitivity reaction J:197334
lung inflammation J:118995
Ltb4r1tm1Tksh/Ltb4r1tm1Tksh
(C.Cg-Ltb4r1tm1Tksh)
abnormal mast cell physiology J:133998
Ltb4r1tm1Tksh/Ltb4r1tm1Tksh
(involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj)
abnormal granulocyte physiology J:118995
Ltb4r2tm1Bodd/Ltb4r2tm1Bodd
(involves: 129S4/SvJaeSor * C57BL/6)
decreased susceptibility to induced arthritis J:163271
immune system phenotype J:163271
Ltb4r2tm1Tksh/Ltb4r2tm1Tksh
(C.Cg-Ltb4r2tm1Tksh)
abnormal mast cell physiology J:133998
Ltb4r2tm1Tksh/Ltb4r2tm1Tksh
(B6.Cg-Ltb4r2tm1Tksh)
decreased susceptibility to type I hypersensitivity reaction J:197334
Ltb/Tnf/Ltatm1Dvk/Ltb/Tnf/Ltatm1Dvk
(involves: C57BL/6)
decreased spleen white pulp amount J:109621
Ltb/Tnf/Ltatm1Dvk/Ltb/Tnf/Ltatm1Dvk
(B6.Cg-Ltb/Tnf/Ltatm1Dvk)
abnormal class switch recombination J:80616
abnormal spleen morphology J:80616
absent axillary lymph nodes J:80616
absent brachial lymph nodes J:80616
absent inguinal lymph nodes J:80616
absent lymph nodes J:80616
absent mesenteric lymph nodes J:80616
absent Peyer's patches J:80616
absent popliteal lymph nodes J:80616
absent spleen germinal center J:80616
absent spleen marginal zone J:80616
decreased IgG level J:80616
decreased spleen B cell follicle number J:80616
decreased spleen white pulp amount J:80616
increased leukocyte cell number J:80616
increased susceptibility to bacterial infection J:80616
Ltb/Tnf/Ltatm1Dvk/Ltb/Tnf/Ltatm1Dvk
(involves: C57BL/6)
decreased spleen white pulp amount J:109621
Ltb/Tnf/Ltatm1Dvk/Ltb/Tnf/Ltatm1Dvk
(B6.Cg-Ltb/Tnf/Ltatm1Dvk)
abnormal class switch recombination J:80616
abnormal spleen morphology J:80616
absent axillary lymph nodes J:80616
absent brachial lymph nodes J:80616
absent inguinal lymph nodes J:80616
absent lymph nodes J:80616
absent mesenteric lymph nodes J:80616
absent Peyer's patches J:80616
absent popliteal lymph nodes J:80616
absent spleen germinal center J:80616
absent spleen marginal zone J:80616
decreased IgG level J:80616
decreased spleen B cell follicle number J:80616
decreased spleen white pulp amount J:80616
increased leukocyte cell number J:80616
increased susceptibility to bacterial infection J:80616
Ltb/Tnf/Ltatm1Dvk/Ltb/Tnf/Ltatm1Dvk
(involves: C57BL/6)
decreased spleen white pulp amount J:109621
Ltb/Tnf/Ltatm1Dvk/Ltb/Tnf/Ltatm1Dvk
(B6.Cg-Ltb/Tnf/Ltatm1Dvk)
abnormal class switch recombination J:80616
abnormal spleen morphology J:80616
absent axillary lymph nodes J:80616
absent brachial lymph nodes J:80616
absent inguinal lymph nodes J:80616
absent lymph nodes J:80616
absent mesenteric lymph nodes J:80616
absent Peyer's patches J:80616
absent popliteal lymph nodes J:80616
absent spleen germinal center J:80616
absent spleen marginal zone J:80616
decreased IgG level J:80616
decreased spleen B cell follicle number J:80616
decreased spleen white pulp amount J:80616
increased leukocyte cell number J:80616
increased susceptibility to bacterial infection J:80616
Ltb/Tnftm1.1Dvk/Ltb/Tnftm1.1Dvk
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal mesenteric lymph node morphology J:58981
abnormal spleen morphology J:58981
absent axillary lymph nodes J:58981
absent brachial lymph nodes J:58981
absent cervical lymph nodes J:58981
absent follicular dendritic cells J:58981
absent germinal center B cells J:58981
absent inguinal lymph nodes J:58981
absent peripheral lymph nodes J:58981
absent Peyer's patches J:58981
absent popliteal lymph nodes J:58981
absent spleen marginal zone J:58981
intermingled spleen red and white pulp J:58981
Ltb/Tnftm1.1Dvk/Ltb/Tnftm1.1Dvk
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal mesenteric lymph node morphology J:58981
abnormal spleen morphology J:58981
absent axillary lymph nodes J:58981
absent brachial lymph nodes J:58981
absent cervical lymph nodes J:58981
absent follicular dendritic cells J:58981
absent germinal center B cells J:58981
absent inguinal lymph nodes J:58981
absent peripheral lymph nodes J:58981
absent Peyer's patches J:58981
absent popliteal lymph nodes J:58981
absent spleen marginal zone J:58981
intermingled spleen red and white pulp J:58981
Ltbtm1Flv/Ltbtm1Flv
(involves: 129S1/Sv * C57BL/6J)
abnormal humoral immune response J:39746
abnormal mesenteric lymph node morphology J:39746
abnormal spleen morphology J:39746
abnormal spleen red pulp morphology J:39746
abnormal spleen white pulp morphology J:39746
absent peripheral lymph nodes J:39746
absent Peyer's patches J:39746
decreased IgA level J:39746
Ltbtm1Kpf/Ltbtm1Kpf
(B6.129P2-Ltbtm1Kpf)
abnormal class switch recombination J:80616
abnormal spleen morphology J:80616
absent spleen marginal zone J:80616
colitis J:158663
decreased IgG level J:80616
decreased spleen B cell follicle number J:80616
decreased spleen white pulp amount J:80616
increased IgM level J:80616
increased leukocyte cell number J:80616
increased susceptibility to bacterial infection J:80616, J:158663
increased susceptibility to bacterial infection induced morbidity/mortality J:158663
Ltbtm1Kpf/Ltbtm1Kpf
(involves: 129P2/OlaHsd * C57BL/6)
abnormal mesenteric lymph node morphology J:58981, J:42508
abnormal spleen follicular dendritic cell network J:42508
abnormal spleen germinal center morphology J:42508
abnormal spleen marginal zone morphology J:42508
abnormal spleen morphology J:58981, J:42508
abnormal spleen red pulp morphology J:42508
absent axillary lymph nodes J:42508
absent brachial lymph nodes J:42508
absent cervical lymph nodes J:58981
absent follicular dendritic cells J:58981
absent inguinal lymph nodes J:42508
absent Peyer's patches J:42508
absent popliteal lymph nodes J:42508
absent spleen marginal zone J:58981
decreased spleen white pulp amount J:109621
increased lymphocyte cell number J:42508
Ltbtm1Kpf/Ltbtm1Kpf
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mesenteric lymph node morphology J:77250
abnormal spleen morphology J:77250
absent axillary lymph nodes J:77250
absent brachial lymph nodes J:77250
absent inguinal lymph nodes J:77250
absent lymph nodes J:77250
absent Peyer's patches J:77250
absent popliteal lymph nodes J:77250
Ltbtm1Krn/Ltbtm1Krn
(C57BL/6-Ltbtm1Krn)
abnormal humoral immune response J:78229
abnormal mesenteric lymph node morphology J:78229
abnormal spleen morphology J:78229
absent cervical lymph nodes J:78229
absent peripheral lymph nodes J:78229
absent Peyer's patches J:78229
decreased IgG1 level J:78229
decreased IgG2a level J:78229
increased IgM level J:78229
increased susceptibility to parasitic infection J:78229
spleen hyperplasia J:78229
Ltbp1tm1a(EUCOMM)Wtsi/Ltbp1+
(B6JTyr;B6N-Ltbp1tm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:175295
Ltbp3tm1Bdvc/Ltbp3tm1Bdvc
(involves: 129S6/SvEvTac)
osteoarthritis J:76213, J:79920
Ltbp4em1(IMPC)Tcp/Ltbp4em1(IMPC)Tcp
(C57BL/6NCrl-Ltbp4em1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
Ltbp4Gt(U3Cre)1Vmel/Ltbp4Gt(U3Cre)1Vmel
(B6.129S2-Ltbp4Gt(U3Cre)1Vmel)
colitis J:78819
enlarged spleen J:78819
proctitis J:78819
Ltbrm1Btlr/Ltbrm1Btlr
(C57BL/6J-Ltbrm1Btlr)
abnormal B cell physiology J:212068
abnormal humoral immune response J:212068
Ltbrm2Btlr/Ltbrm2Btlr
(C57BL/6J-Ltbrm2Btlr)
abnormal humoral immune response J:254823
abnormal IgG level J:254823
Ltbrm3Btlr/Ltbrm3Btlr
(C57BL/6J-Ltbrm3Btlr)
impaired natural killer cell mediated cytotoxicity J:264642
increased NK T cell number J:264642
Ltbrm4Btlr/Ltbrm4Btlr
(C57BL/6J-Ltbrm4Btlr)
decreased alpha-beta T cell number J:264820
decreased CD4-positive, alpha-beta T cell number J:264820
decreased CD8-positive, alpha-beta T cell number J:264820
decreased NK cell number J:264820
decreased single-positive T cell number J:264820
increased B cell number J:264820
increased B-1 B cell number J:264820
Ltbrtm1.1Thhe/Ltbrtm1.1Thhe
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal macrophage physiology J:183109
Ltbrtm1Avt/Ltbrtm1Avt
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
increased susceptibility to bacterial infection J:158663
Ltbrtm1Avt/Ltbrtm1Avt
Tg(Lck-cre)I57Jxm/0

(Not Specified)
immune system phenotype J:158663
Ltbrtm1Avt/Ltbrtm1Avt
Tg(Rorc-cre)1Litt/0

(Not Specified)
abnormal chemokine level J:158663
decreased neutrophil cell number J:158663
increased susceptibility to bacterial infection J:158663
increased susceptibility to bacterial infection induced morbidity/mortality J:158663
Ltbrtm1Avt/Ltbrtm1Avt
Tg(Vil1-cre)997Gum/0

(involves: C57BL/6J * SJL)
decreased neutrophil cell number J:158663
increased susceptibility to bacterial infection J:158663
Ltbrtm1Kpf/Ltbrtm1Kpf
(involves: 129P2/OlaHsd)
abnormal gamma-delta T cell morphology J:169863
abnormal immune system morphology J:48837
abnormal immune system organ morphology J:48837
abnormal immune system physiology J:48837
abnormal spleen B cell follicle morphology J:48837
abnormal spleen morphology J:48837
abnormal spleen periarteriolar lymphoid sheath morphology J:48837
absent marginal zone B cells J:48837
absent peripheral lymph nodes J:48837
absent Peyer's patches J:48837
decreased IgE level J:86810
decreased interleukin-17 secretion J:169863
enlarged spleen J:48837
immune system phenotype J:169863
increased B cell number J:48837
increased lymphocyte cell number J:48837
increased T cell number J:48837
Ltbrtm1Kpf/Ltbrtm1Kpf
(involves: 129P2/OlaHsd * C57BL/6)
decreased spleen white pulp amount J:109621
Ltbrtm1Kpf/Ltbrtm1Kpf
(B6.129P2-Ltbrtm1Kpf)
decreased neutrophil cell number J:158663
Ltbrtm1Kpf/Ltbrtm1Kpf
Tg(Lck-Tnfsf14)24Yxf/?

(B6.Cg-Ltbrtm1Kpf Tg(Lck-Tnfsf14)24Yxf)
immune system phenotype J:128976
Ltbrtm1Mmat/Ltbrtm1Mmat
(involves: C57BL/6 * CBA)
abnormal lymphocyte morphology J:173115
abnormal spleen morphology J:173115
abnormal thymus epithelium morphology J:173115
abnormal thymus medulla morphology J:173115
absent follicular dendritic cells J:173115
absent mesenteric lymph nodes J:173115
absent spleen germinal center J:173115
small thymus medulla J:173115
Ltbrtm1Mmat/Ltbrtm1Mmat
Tnfsf11tm1Pngr/Tnfsf11tm1Pngr

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal thymus epithelium morphology J:173115
Ltc4stm1Blam/Ltc4stm1Blam
(involves: 129S7/SvEvBrd * C57BL/6)
immune system phenotype J:110309
respiratory system inflammation J:88647
Ltc4stm1Blam/Ltc4stm1Blam
(involves: 129S7/SvEvBrd * BALB/c)
abnormal hypersensitivity reaction J:87909
abnormal type I hypersensitivity reaction J:87909
Ltc4stm1Blam/Ltc4stm1Blam
(C.129S7-Ltc4stm1Blam)
autoimmune response J:182213
Ltc4stm1Blam/Ltc4stm1Blam
(B6.129S7-Ltc4stm1Blam)
decreased susceptibility to type I hypersensitivity reaction J:197334
Ltftm1Omc/Ltftm1Omc
(either: 129S/SvEv or (involves: 129S/SvEv * C57BL/6))
decreased spleen iron level J:81005
Ltn1tm1b(EUCOMM)Hmgu/Ltn1tm1b(EUCOMM)Hmgu
(C57BL/6N-Ltn1tm1b(EUCOMM)Hmgu/Ccpcz)
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
Ltv1em1(IMPC)J/Ltv1+
(C57BL/6NJ-Ltv1em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Ltxs2BALB/cAnPt/Ltxs2DBA/2NCr
(involves: BALB/cAnPt * DBA/2NCr)
decreased susceptibility to infection J:103336
Ltxs2DBA/2NCr/Ltxs2DBA/2NCr
(involves: BALB/cAnPt * DBA/2NCr)
decreased susceptibility to infection J:103336
Ltxs3BALB/cAnPt/Ltxs3DBA/2NCr
(involves: BALB/cAnPt * DBA/2NCr)
decreased susceptibility to infection J:103336
Ltxs3DBA/2NCr/Ltxs3DBA/2NCr
(involves: BALB/cAnPt * DBA/2NCr)
decreased susceptibility to infection J:103336
Luc7lem1(IMPC)Mbp/Luc7lem1(IMPC)Mbp
(C57BL/6N-Luc7lem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Lumtm1Wwk/Lumtm1Wwk
(involves: 129P2/OlaHsd)
abnormal inflammatory response J:128992
decreased neutrophil cell number J:128992
Lxw1BXSB/Scr/?
(involves: BXSB/Scr * NZW/LacScr)
increased anti-chromatin antibody level J:86924
Lxw2NZW/LacScr/Lxw2NZW/LacScr
(involves: BXSB/Scr * NZW/LacScr)
glomerulonephritis J:86924
Lxw3NZW/LacScr/?
(involves: BXSB/Scr * NZW/LacScr)
increased anti-chromatin antibody level J:86924
Lxw5BXSB/Scr/Lxw5BXSB/Scr
(involves: BXSB/Scr * NZW/LacScr)
enlarged spleen J:86924
Lxw5NZW/LacScr/Lxw5BXSB/Scr
(involves: BXSB/Scr * NZW/LacScr)
enlarged spleen J:86924
Lxw6NZW/LacScr/Lxw6NZW/LacScr
(involves: BXSB/Scr * NZW/LacScr)
enlarged spleen J:86924
Ly6atm1Pmf/Ly6atm1Pmf
(B6.129P2-Ly6atm1Pmf)
abnormal immunoglobulin level J:42594
abnormal myeloid leukocyte morphology J:81387
abnormal T cell proliferation J:42594
decreased granulocyte number J:81387
decreased monocyte cell number J:81387
increased lymphocyte cell number J:81387
Ly6atm1Pmf/Ly6atm1Pmf
(C.129P2-Ly6atm1Pmf)
abnormal osteoclast differentiation J:83409
decreased osteoclast cell number J:83409
Ly6atm2(RUNX1)Grau/Ly6a+
(involves: 129X1/SvJ * C57BL/6J)
abnormal spleen B cell follicle morphology J:93408
enlarged spleen J:93408
increased leukocyte cell number J:93408
increased neutrophil cell number J:93408
myeloid hyperplasia J:93408
Ly6etm1c(EUCOMM)Hmgu/Ly6etm1c(EUCOMM)Hmgu
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(B6.Cg-Ly6etm1c(EUCOMM)Hmgu Commd10Tg(Vav1-icre)A2Kio)
abnormal mononuclear cell morphology J:291868
decreased B cell number J:291868
decreased CD4-positive, alpha-beta T cell number J:291868
decreased dendritic cell number J:291868
decreased inflammatory response J:291868
decreased macrophage cell number J:291868
decreased neutrophil cell number J:291868
decreased NK cell number J:291868
increased susceptibility to Coronaviridae infection J:291868
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:291868
Ly6gtm2621(cre)Arte/Ly6gtm2621(cre)Arte
(involves: C57BL/6)
immune system phenotype J:227159
Ly9tm1Mckn/Ly9tm1Mckn
(involves: 129/Sv * C57BL/6)
abnormal cytokine secretion J:105482
abnormal T-helper 2 cell morphology J:105482
decreased T cell proliferation J:105482
Ly75tm1Mnz/Ly75tm1Mnz
(Not Specified)
abnormal CD8-positive, alpha beta T cell morphology J:97290
abnormal cytotoxic T cell physiology J:97289
Ly86tm1a(KOMP)Wtsi/Ly86+
(C57BL/6N-Ly86tm1a(KOMP)Wtsi/MbpMmucd)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Ly86tm1a(KOMP)Wtsi/Ly86tm1a(KOMP)Wtsi
(C57BL/6N-Ly86tm1a(KOMP)Wtsi/MbpMmucd)
increased lymphocyte cell number J:211773
Ly86tm1Kmiy/Ly86tm1Kmiy
(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell proliferation J:109720
decreased IgG2b level J:137066
decreased IgG3 level J:137066
increased IgG level J:109720
increased IgM level J:109720
Ly96m1Btlr/Ly96m1Btlr
(C57BL/6J-Ly96m1Btlr)
decreased interleukin-1 beta secretion J:265259
decreased macrophage apoptosis J:265259
decreased tumor necrosis factor secretion J:265259
Ly96tm1Kmiy/Ly96tm1Kmiy
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune cell physiology J:92494
abnormal macrophage physiology J:92494
decreased B cell proliferation J:92494
decreased interleukin-6 secretion J:92494
decreased susceptibility to endotoxin shock J:92494
decreased tumor necrosis factor secretion J:92494
impaired neutrophil recruitment J:92479
increased susceptibility to bacterial infection J:92494
Lyg1tm1(KOMP)Vlcg/Lyg1tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
decreased CD4-positive, alpha-beta T cell number J:256594
decreased CD8-positive, alpha-beta T cell number J:256594
decreased interferon-gamma secretion J:256594
Lyl1tm1Fsky/Lyl1tm1Fsky
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:116300
arrested B cell differentiation J:116300
decreased B cell number J:116300
decreased pro-B cell number J:116300
Lynm1Anu/Lynm1Anu
(C57BL/6JAnu-Lynm1Anu)
decreased B cell number J:195155
LynM1Btlr/Lyn+
(C57BL/6J-LynM1Btlr)
decreased B cell number J:214511
increased neutrophil cell number J:214511
LynM1Btlr/LynM1Btlr
(C57BL/6J-LynM1Btlr)
decreased B cell number J:214511
increased neutrophil cell number J:214511
Lynm2Anu/Lynm2Anu
(C57B/6JAnu-Lynm2Anu/AnuApb)
decreased mature B cell number J:104190
increased immature B cell number J:104190
LynM2Btlr/Lyn+
(C57BL/6J-LynM2Btlr)
decreased IgG level J:217146
decreased IgM level J:217146
impaired humoral immune response J:217146
LynM2Btlr/LynM2Btlr
(C57BL/6J-LynM2Btlr)
decreased IgG level J:217146
decreased IgM level J:217146
impaired humoral immune response J:217146
LynM3Btlr/Lyn+
(C57BL/6J-LynM3Btlr)
decreased T cell number J:236679
increased B-1 B cell number J:236679
increased dendritic cell number J:236679
increased macrophage cell number J:236679
LynM3Btlr/LynM3Btlr
(C57BL/6J-LynM3Btlr)
decreased T cell number J:236679
increased B-1 B cell number J:236679
increased dendritic cell number J:236679
increased macrophage cell number J:236679
Lynm4Btlr/Lynm4Btlr
(C57BL/6J-Lynm4Btlr)
decreased IgG level J:272816
impaired humoral immune response J:272816
Lynmld4/Lynmld4
(involves: C57BL/6)
abnormal B cell activation J:144799
abnormal B cell morphology J:144799
abnormal myelopoiesis J:144799
decreased follicular B cell number J:144799
decreased marginal zone B cell number J:144799
decreased transitional stage B cell number J:144799
glomerulonephritis J:144799
increased anti-double stranded DNA antibody level J:144799
increased IgE level J:144799
increased IgM level J:144799
increased macrophage cell number J:144799
increased neutrophil cell number J:144799
increased T cell number J:144799
peritoneal inflammation J:144799
spleen hypoplasia J:144799
Lynmld4/Lynmld4
Mpltm1Wsa/Mpltm1Wsa

(B6.129S1-Mpltm1Wsa)
decreased leukocyte cell number J:144799
Lyntm1.1Calo/Lyntm1.1Calo
Myd88tm1Defr/Myd88tm1Defr
Tg(Itgax-cre)1-1Reiz/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:200745
Lyntm1.1Calo/Lyntm1.1Calo
Tg(Itgax-cre)1-1Reiz/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal circulating chemokine level J:200745
abnormal circulating cytokine level J:200745
abnormal dendritic cell physiology J:200745
abnormal leukocyte physiology J:200745
abnormal T cell activation J:200745
enlarged lymph nodes J:200745
enlarged spleen J:200745
glomerulonephritis J:200745
increased activated T cell number J:200745
increased autoantibody level J:200745
increased circulating interferon-gamma level J:200745
increased circulating interleukin-1 beta level J:200745
increased circulating interleukin-6 level J:200745
increased circulating interleukin-12 level J:200745
increased circulating interleukin-17 level J:200745
increased circulating tumor necrosis factor level J:200745
increased dendritic cell number J:200745
increased granulocyte number J:200745
increased inflammatory response J:200745
increased leukocyte cell number J:200745
increased monocyte cell number J:200745
increased plasma cell number J:200745
increased T cell number J:200745
liver inflammation J:200745
lung inflammation J:200745
lymph node hyperplasia J:200745
myeloid hyperplasia J:200745
skin inflammation J:200745
Lyntm1Ard/Lyn+
Ptpn6me-v/Ptpn6+
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mature B cell morphology J:110531
Lyntm1Ard/Lyn+
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mature B cell morphology J:110531
Lyntm1Ard/Lyntm1Ard
(involves: 129P2/OlaHsd)
abnormal circulating complement protein level J:161523
abnormal level of surface class II molecules J:161523
decreased spleen red pulp amount J:72269
decreased spleen white pulp amount J:72269
enlarged spleen J:72269
glomerulonephritis J:161523
increased anti-double stranded DNA antibody level J:161523
increased anti-nuclear antigen antibody level J:161523
increased basophil cell number J:161523
increased IgA level J:161523
increased IgE level J:161523
increased IgG2b level J:161523
increased IgM level J:161523
increased mast cell number J:161523
increased neutrophil cell number J:72269
Lyntm1Ard/Lyntm1Ard
(B6.129P2-Lyntm1Ard)
abnormal B cell activation J:144799
abnormal B cell morphology J:144799
abnormal myelopoiesis J:144799
decreased follicular B cell number J:144799
decreased marginal zone B cell number J:144799
decreased transitional stage B cell number J:144799
glomerulonephritis J:144799
increased anti-double stranded DNA antibody level J:144799
increased anti-nuclear antigen antibody level J:144799
increased T cell number J:144799
peritoneal inflammation J:144799
spleen hypoplasia J:144799
Lyntm1Ard/Lyntm1Ard
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell activation J:110531
abnormal B cell negative selection J:110531
abnormal mature B cell morphology J:110531
absent B-1 B cells J:110531
increased IgM level J:110531
Lyntm1b(EUCOMM)Hmgu/Lyntm1b(EUCOMM)Hmgu
(C57BL/6N-Lyntm1b(EUCOMM)Hmgu/H)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased eosinophil cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
small thymus J:211773
Lyntm1Mhi/Lyntm1Mhi
(involves: 129S1/Sv)
decreased spleen weight J:72269
increased neutrophil cell number J:72269
Lyntm1Sor/Lyntm1Sor
(involves: 129S4/SvJae)
decreased B cell number J:42037
decreased mature B cell number J:42037
enlarged lymph nodes J:42037
enlarged spleen J:42037
increased anti-double stranded DNA antibody level J:42037
increased B cell proliferation J:42037
Lyntm1Sor/Lyntm1Sor
(B6.129S4-Lyntm1Sor)
abnormal inflammatory response J:113463
Lyntm1Sor/Lyntm1Sor
(involves: 129S4/SvJaeSor)
abnormal chemokine level J:80658
abnormal circulating chemokine level J:200745
abnormal circulating cytokine level J:200745
abnormal dendritic cell physiology J:200745
abnormal macrophage physiology J:80658
abnormal microglial cell physiology J:80658
decreased B cell number J:200745
decreased follicular B cell number J:146161
decreased marginal zone B cell number J:146161
decreased mature B cell number J:146161
decreased transitional stage B cell number J:146161
glomerulonephritis J:146161, J:200745
increased anti-double stranded DNA antibody level J:146161
increased autoantibody level J:200745
increased B cell proliferation J:146161
increased circulating interferon-gamma level J:200745
increased circulating interleukin-6 level J:200745
increased circulating interleukin-12 level J:200745
increased circulating interleukin-17 level J:200745
increased IgA level J:146161
increased IgM level J:146161
increased plasma cell number J:200745
liver inflammation J:146161
myeloid hyperplasia J:146161
spleen hyperplasia J:146161
Lyntm1Sor/Lyntm1Sor
(involves: 129S4/SvJaeSor * C57BL/6)
decreased B cell number J:71174
decreased B-1 B cell number J:71174
decreased mature B cell number J:71174
enlarged spleen J:71174
glomerulonephritis J:71174
increased anti-double stranded DNA antibody level J:71174
increased B cell proliferation J:71174
increased IgA level J:71174
increased IgG1 level J:71174
increased IgG2b level J:71174
increased IgG level J:71174
increased IgM level J:71174
increased susceptibility to systemic lupus erythematosus J:71174
Lyntm1Tya/Lyntm1Tya
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:29751
abnormal class switch recombination J:29751
abnormal spleen morphology J:29751
decreased B cell number J:29751
decreased B cell proliferation J:29751
decreased lymphocyte cell number J:29751
enlarged lymph nodes J:29751
enlarged spleen J:29751
glomerulonephritis J:29751
increased anti-double stranded DNA antibody level J:29751
increased IgA level J:29751
increased IgM level J:29751
increased immunoglobulin level J:29751
increased spleen white pulp amount J:29751
small Peyer's patches J:29751
Lynweeb/Lynweeb
(C57BL/6-Lynweeb)
decreased follicular B cell number J:146161
decreased marginal zone B cell number J:146161
decreased mature B cell number J:146161
decreased transitional stage B cell number J:146161
disorganized spleen B cell follicle J:146161
glomerulonephritis J:146161
increased anti-double stranded DNA antibody level J:146161
increased B cell proliferation J:146161
increased IgM level J:146161
liver inflammation J:146161
spleen hyperplasia J:146161
Lynf1C57BL/10J/Lynf1C57BL/10J
Lynf3C57BL/10J/Lynf3C57BL/10J

(involves: B10.O20 * O20/A)
abnormal acute inflammation J:128728
Lynf2C57BL/10J/Lynf2C57BL/10J
Lynf3C57BL/10J/Lynf3C57BL/10J

(involves: B10.O20 * O20/A)
abnormal acute inflammation J:128728
Lynf2O20/A/Lynf2O20/A
(involves: B10.O20 * O20/A)
abnormal acute inflammation J:128728
Lynf4C57BL/10J/Lynf4C57BL/10J
(involves: B10.O20 * O20/A)
abnormal acute inflammation J:128728
Lynf4C57BL/10J/Lynf4O20/A
(involves: B10.O20 * O20/A)
abnormal acute inflammation J:128728
Lypd8tm2Ktak/Lypd8tm2Ktak
(B6.Cg-Lypd8tm2Ktak)
increased susceptibility to colitis induced morbidity/mortality J:232706
increased susceptibility to induced colitis J:232706
Lysetem1Janc/Lysetem1Janc
(C57BL/6J-Tmem251em1Janc)
decreased susceptibility to viral infection J:330704
Lysetem1Janc/Lysetem2Janc
(C57BL/6J-Tmem251em1Janc Tmem251em2Janc)
decreased susceptibility to viral infection J:330704
Lysetem2Janc/Lysetem2Janc
(C57BL/6J-Tmem251em2Janc)
decreased susceptibility to viral infection J:330704
Lystbg-2Btlr/Lystbg-2Btlr
(C57BL/6J-Lystbg-2Btlr)
abnormal NK cell physiology J:133617
increased susceptibility to Herpesvirales infection J:133617
Lystbg-2J/Lystbg-2J
(C3.Cg-Lystbg-2J/J)
abnormal susceptibility to infection J:147940
decreased susceptibility to fungal infection J:147940
Lystbg-5Btlr/Lyst+
(C57BL/6J-Lystbg-5Btlr)
impaired macrophage phagocytosis J:217864
Lystbg-5Btlr/Lystbg-5Btlr
(C57BL/6J-Lystbg-5Btlr)
impaired macrophage phagocytosis J:217864
Lystbg-6Btlr/Lystbg-6Btlr
(C57BL/6J-Lystbg-6Btlr)
increased susceptibility to Herpesvirales infection J:220065
Lystbg-Btlr/Lystbg-Btlr
(C57BL/6J-Lystbg-Btlr)
abnormal NK cell physiology J:133616
increased susceptibility to bacterial infection J:133616
increased susceptibility to Herpesvirales infection J:133616
Lystbg-grey/Lystbg-grey
(C57BL/6-Lystbg-grey)
abnormal dermal mast cell morphology J:106442
Lystbg-J/Lystbg-J
(C57BL/6J-Lystbg-J/J)
abnormal granulocyte morphology J:34814
abnormal neutrophil morphology J:34814
decreased macrophage cell number J:34814
impaired natural killer cell mediated cytotoxicity J:34814
Lystbg-J/Lystbg-J
Prkdcscid/Prkdcscid

(B6.Cg-Lystbg-J Prkdcscid/Sz)
abnormal complement pathway J:34814
abnormal granulocyte morphology J:34814
abnormal level of surface class II molecules J:34814
abnormal lymph node morphology J:34814
abnormal neutrophil morphology J:34814
abnormal Peyer's patch morphology J:34814
abnormal spleen white pulp morphology J:34814
abnormal thymus morphology J:34814
decreased B cell number J:34814
decreased CD4-positive, alpha-beta T cell number J:34814
decreased CD8-positive, alpha-beta T cell number J:34814
decreased immunoglobulin level J:34814
decreased lymphocyte cell number J:34814
decreased pre-B cell number J:34814
decreased T cell number J:34814
impaired natural killer cell mediated cytotoxicity J:34814
increased eosinophil cell number J:34814
increased granulocyte number J:34814
increased macrophage cell number J:34814
increased monocyte cell number J:34814
increased neutrophil cell number J:34814
increased NK cell number J:34814
small Peyer's patches J:34814
small thymus J:34814
spleen hypoplasia J:34814
thymus cyst J:34814
Lystbg-Lac/Lystbg-Lac
(CBA/CaLac-Lystbg-Lac)
absent NK T cells J:29745
Lystbg/Lystbg
(B6.C3Rl-Lystbg)
abnormal eosinophil morphology J:5078
abnormal lymphocyte morphology J:5078
abnormal neutrophil morphology J:5078
alveolitis J:110157
decreased cytotoxic T cell cytolysis J:6692
impaired natural killer cell mediated cytotoxicity J:6302, J:6213
Lystbg/Lystbg
(B6.C3Rl-Lystbg/J)
abnormal NK cell physiology J:6801
increased susceptibility to parasitic infection J:6946
Lystbg/Lystbg
Prkdcscid/Prkdcscid

(Not Specified)
increased susceptibility to infection J:4752
Lyve1tm1.1(EGFP/cre)Cys/Lyve1+
Sphk1tm2Cgh/Sphk1tm2Cgh
Sphk2tm1.1Cgh/Sphk2tm1.1Cgh

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal leukocyte migration J:156826
abnormal lymph node morphology J:156826
abnormal lymphatic vessel morphology J:156826
abnormal lymphocyte cell number J:156826
abnormal Peyer's patch T cell area morphology J:156826
decreased B cell number J:156826
decreased splenocyte number J:156826
decreased T cell number J:156826
immune system phenotype J:156826
Lyve1tm1Dgjk/Lyve1tm1Dgjk
(involves: 129 * C57BL/6)
immune system phenotype J:117678
Lyve1tm1Lhua/Lyve1tm1Lhua
(B6.129S1-Lyve1tm1Lhua)
abnormal lymph circulation J:117713
lymphangiectasis J:117713
Lyz2tm1(cre)Ifo/0
Nup85tm1.1Yter/Nup85tm1.1Yter

(involves: 129P2/OlaHsd * C57BL/6)
decreased macrophage cell number J:292726
Lyz2tm1(cre)Ifo/Lyz2+
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:172024
Lyz2tm1(cre)Ifo/Lyz2+
Nfkbiztm1.1Muta/Nfkbiztm1.1Muta

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:194832
Lyz2tm1(cre)Ifo/Lyz2+
Pdcd10tm1Wami/Pdcd10tm1Wami

(involves: 129 * 129P2/OlaHsd * C57BL/6)
abnormal neutrophil morphology J:256076
abnormal neutrophil physiology J:256076
Lyz2tm1(cre)Ifo/Lyz2+
Pikfyvetm1b(EUCOMM)Hmgu/Pikfyvetm1b(EUCOMM)Hmgu

(involves: 129P2/OlaHsd * C57BL/6N)
abnormal alveolar macrophage morphology J:244776
decreased alveolar macrophage number J:244776
decreased regulatory T cell number J:244776
immune system phenotype J:244776
increased eosinophil cell number J:244776
increased interleukin-4 secretion J:244776
increased interleukin-13 secretion J:244776
increased susceptibility to type I hypersensitivity reaction J:244776
Lyz2tm1(cre)Ifo/Lyz2+
Selenowtm1c(EUCOMM)Wtsi/Selenowtm1c(EUCOMM)Wtsi

(B6.Cg-Selenowtm1c(EUCOMM)Wtsi Lyz2tm1(cre)Ifo)
abnormal osteoclast differentiation J:317012
Lyz2tm1(cre)Ifo/Lyz2+
St18tm1c(KOMP)Wtsi/St18tm1c(KOMP)Wtsi

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N)
immune system phenotype J:298828
increased circulating interleukin-1 beta level J:298828
increased inflammatory response J:298828
Lyz2tm1(cre)Ifo/Lyz2tm1(cre)Ifo
Nrrostm1Wouy/Nrrostm1Wouy

(involves: 129P2/OlaHsd)
abnormal cellular extravasation J:209569
increased susceptibility to experimental autoimmune encephalomyelitis J:209569
Lyz2tm1(HBEGF)Mtka/Lyz2+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal alveolar macrophage morphology J:145285
Lyz2tm1.1Graf/Lyz2tm1.1Graf
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
increased inflammatory response J:82642
m1Hefl/m1Hefl
(C3HeB/FeJ-m1Hefl)
decreased B cell number J:137446
X/m1Nish
(involves: BALB/c * C57BL/6N)
absent B cells J:204833
absent Peyer's patches J:204833
decreased NK cell number J:204833
X/m1Nish
(involves: C57BL/6N)
abnormal B cell differentiation J:204833
abnormal NK cell differentiation J:204833
absent B cells J:204833
absent B-1 B cells J:204833
absent B-2 B cells J:204833
absent Peyer's patches J:204833
decreased B cell number J:204833
decreased B-1 B cell number J:204833
decreased IgG level J:204833
decreased IgM level J:204833
decreased immature B cell number J:204833
decreased NK cell number J:204833
decreased T cell proliferation J:204833
immune system phenotype J:204833
small lymph nodes J:204833
m1Nish/m1Nish+
(involves: BALB/c * C57BL/6N)
immune system phenotype J:204833
m1Nish/m1Nish+
(involves: C57BL/6N)
immune system phenotype J:204833
m2Hefl/m2Hefl
(C3HeB/FeJ-m2Hefl)
absent B cells J:137446
absent T cells J:137446
m3Hefl/m3Hefl
(C3HeB/FeJ-m3Hefl)
decreased CD8-positive, alpha-beta T cell number J:137446
decreased NK cell number J:137446
m4Hefl/m4Hefl
(C3HeB/FeJ-m4Hefl)
decreased T cell number J:137446
m5Hefl/m5Hefl
(C3HeB/FeJ-m5Hefl)
decreased T cell number J:137446
M6prem1(IMPC)Mbp/M6prem1(IMPC)Mbp
(C57BL/6N-M6prem1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
M7321Wlst/M7321Wlst+
(involves: 129S1/SvImJ * C57BL/6J)
abnormal thrombopoiesis J:189491
M7324Wlst/M7324Wlst+
(involves: 129S1/SvImJ * C57BL/6J)
abnormal thrombopoiesis J:189491
M7325Wlst/M7325Wlst+
(involves: 129S1/SvImJ * C57BL/6J)
abnormal thrombopoiesis J:189491
m12137Asr/m12137Asr+
(C57BL/6J-m12137Asr)
decreased osteoclast cell number J:132290
Macroh2a1tm1.1Oxbo/Macroh2a1tm1.1Oxbo
(B6.Cg-Macroh2a1tm1.1Oxbo)
decreased B cell number J:293382
decreased neutrophil cell number J:293382
increased eosinophil cell number J:293382
increased lymphocyte cell number J:293382
Macroh2a1tm1Peh/Macroh2a1tm1Peh
Macroh2a2tm1.1Peh/Macroh2a2tm1.1Peh

(129S6.Cg-Macroh2a2tm1.1Peh Macroh2a1tm1Peh)
blepharitis J:220524
Mad2l1tm1Sorg/Mad2l1+
(involves: 129S2/SvPas * C57BL/6)
increased spleen germinal center number J:62829
Madcam1tm1.2Nwag/Madcam1tm1.2Nwag
(B6.129P2-Madcam1tm1.2Nwag)
abnormal B cell physiology J:169739
decreased B cell number J:169739
decreased IgA level J:169739
decreased plasma cell number J:169739
increased plasma cell number J:169739
small Peyer's patches J:169739
MaeaGt(XG702)Byg/MaeaGt(XG702)Byg
(involves: 129P2/OlaHsd * C57BL/6J)
decreased macrophage cell number J:114865
Mafem1(IMPC)Mbp/Maf+
(C57BL/6N-Mafem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
MafOfl/MafOfl
(either: 102/ElH or C3H/HeH)
tubular nephritis J:82475
Maftm1Glm/Maftm1Glm
(involves: 129/Sv * BALB/c)
decreased interleukin-4 secretion J:78382
Mafbtm1Jeng/Mafbtm1Jeng
(involves: 129P2/OlaHsd * C57BL/6J)
immune system phenotype J:111415
Mafgtm1Jeng/Mafgtm1Jeng
Mafktm1Jeng/Mafktm1Jeng

(involves: 129S1/Sv * 129X1/SvJ)
enlarged spleen J:61142
Magtm1.1(KOMP)Vlcg/Magtm1.1(KOMP)Vlcg
(C57BL/6N-Magtm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Magtm1Rod/Magtm1Rod
(involves: 129S1/Sv * 129X1/SvJ)
increased B cell proliferation J:217719
Maged1tm1.1Urfm/Maged1tm1.1Urfm
(involves: 129P2/OlaHsd)
abnormal tumor necrosis factor level J:157549
Magi2tm1Key/Magi2tm1Key
(involves: 129S4/SvJae)
tubulointerstitial nephritis J:213553
Magixem1(IMPC)Hmgu/Y
(C57BL/6NCrl-Magixem1(IMPC)Hmgu/Ieg)
decreased leukocyte cell number J:211773
Magt1Gt(IST13422E1)Tigm/Y
(involves: C57BL/6N)
abnormal B cell morphology J:260923
decreased plasma cell number J:260923
decreased T cell number J:260923
increased B cell number J:260923
increased B cell proliferation J:260923
increased marginal zone B cell number J:260923
Malat1tm1.2Dlsp/Malat1tm1.2Dlsp
(B6J.Cg-Malat1tm1.2Dlsp)
brain inflammation J:239375
Malrd1em1(IMPC)Mbp/Malrd1em1(IMPC)Mbp
(C57BL/6N-Malrd1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Malt1m1Btlr/Malt1+
(C57BL/6J-Malt1m1Btlr)
impaired humoral immune response J:221474
Malt1m1Btlr/Malt1m1Btlr
(C57BL/6J-Malt1m1Btlr)
impaired humoral immune response J:221474
Malt1m2Btlr/Malt1+
(C57BL/6J-Malt1m2Btlr)
decreased IgM level J:224671
impaired humoral immune response J:224671
Malt1m2Btlr/Malt1m2Btlr
(C57BL/6J-Malt1m2Btlr)
decreased IgG level J:224671
decreased IgM level J:224671
impaired humoral immune response J:224671
Malt1m3Btlr/Malt1+
(C57BL/6J-Malt1m3Btlr)
decreased IgM level J:224672
impaired humoral immune response J:224672
Malt1m3Btlr/Malt1m3Btlr
(C57BL/6J-Malt1m3Btlr)
decreased IgG level J:224672
decreased IgM level J:224672
impaired humoral immune response J:224672
Malt1tm1Mak/Malt1tm1Mak
(involves: 129P2/OlaHsd)
abnormal dendritic cell physiology J:111706
decreased IgG level J:109545
decreased IgM level J:109545
decreased T cell proliferation J:109545
Malt1tm1Vmd/Malt1tm1Vmd
(involves: C57BL/6N)
abnormal B cell differentiation J:86770
abnormal double-negative T cell morphology J:86770
abnormal immune system morphology J:86770
abnormal spleen marginal zone morphology J:86770
abnormal T cell differentiation J:86770
abnormal T cell proliferation J:86770
absent B-1a cells J:86770
decreased immunoglobulin level J:86770
decreased interleukin-2 secretion J:86770
Maml1tm1Mkit/Maml1tm1Mkit
(involves: 129P2/OlaHsd * C57BL/6)
decreased marginal zone B cell number J:122286
decreased thymocyte number J:122286
increased double-negative T cell number J:122286
Mamld1tm1.1(NCOM)Mfgc/Y
(C57BL/6N-Mamld1tm1.1(NCOM)Mfgc/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Man2a1tm1Jxm/Man2a1tm1Jxm
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immune serum protein physiology J:74579
abnormal immune system physiology J:74579
abnormal self tolerance J:74579
abnormal spleen morphology J:74579
enlarged spleen J:41621
glomerulonephritis J:74579
immune system phenotype J:74579
increased IgA level J:74579
increased IgG level J:74579
increased IgM level J:74579
increased memory T cell number J:74579
liver inflammation J:74579
lung inflammation J:74579
Man2a1tm1Jxm/Man2a1tm1Jxm
Rag1tm1Mom/Rag1tm1Mom

(B6.129-Rag1tm1Mom Man2a1tm1Jxm)
kidney inflammation J:124348
Man2b1tm1Psa/Man2b1tm1Psa
(involves: 129 * C57BL/6J)
abnormal Kupffer cell morphology J:56659
abnormal spleen red pulp morphology J:56659
Man2b2tm1b(KOMP)Wtsi/Man2b2tm1b(KOMP)Wtsi
(C57BL/6N-Man2b2tm1b(KOMP)Wtsi/Tcp)
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
Man2c1tm1.1Tbec/Man2c1tm1.1Tbec
(B6N.129P2-Man2c1tm1.1Tbec)
abnormal microglial cell activation J:205550
Manbatm1Khf/Manbatm1Khf
(B6.129-Manbatm1Khf)
abnormal Kupffer cell morphology J:105427
Map2k3tm1Flv/Map2k3tm1Flv
(involves: 129S1/Sv)
abnormal CD4-positive, alpha-beta T cell physiology J:85266
decreased T cell apoptosis J:85266
Map2k3tm1Flv/Map2k3tm1Flv
(B6.129S1-Map2k3tm1Flv)
increased susceptibility to bacterial infection J:124327
Map2k6tm1Flv/Map2k6tm1Flv
(involves: 129S1/Sv)
abnormal thymocyte apoptosis J:85266
Map2k6tm1Ina/Map2k6tm1Ina
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal thymus cell ratio J:100093
Map3k1tm1Glj/Map3k1tm1Glj
(involves: 129S/SvEv)
heart inflammation J:78068
immune system phenotype J:62909
Map3k2tm1Bisu/Map3k2tm1Bisu
(Not Specified)
abnormal cytokine secretion J:78072
abnormal T cell activation J:78072
increased T cell proliferation J:78072
Map3k3tm1Bisu/Map3k3tm2Bisu
Tg(Lck-cre)548Jxm/0

(involves: C57BL/6 * CBA)
abnormal T cell physiology J:145923
abnormal T cell proliferation J:145923
decreased CD4-positive, alpha-beta T cell number J:145923
decreased CD8-positive, alpha-beta T cell number J:145923
spleen hypoplasia J:145923
Map3k3tm1Kuro/Map3k3tm1Kuro
Tg(Lck-cre)1Jtak/0

(involves: C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:147103
decreased CD8-positive, alpha-beta T cell number J:147103
decreased double-positive T cell number J:147103
decreased interferon-gamma secretion J:147103
decreased interleukin-2 secretion J:147103
decreased single-positive T cell number J:147103
decreased T cell proliferation J:147103
decreased thymocyte number J:147103
increased double-negative T cell number J:147103
Map3k4tm1Flv/Map3k4tm1Flv
(involves: 129S6/SvEvTac * C57BL/6)
abnormal T-helper 1 physiology J:90112
decreased interferon-gamma secretion J:90112
Map3k5tm1Hijo/Map3k5tm1Hijo
(involves: 129S4/SvJae * C57BL/6J)
immune system phenotype J:251158
Map3k7tm1.1Gkl/Map3k7tm1.1Gkl
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating interleukin-10 level J:211916
decreased interleukin-10 secretion J:211916
increased circulating interleukin-1 beta level J:211916
increased circulating tumor necrosis factor level J:211916
increased inflammatory response J:211916
increased interleukin-1 beta secretion J:211916
increased interleukin-6 secretion J:211916
increased interleukin-10 secretion J:211916
increased susceptibility to endotoxin shock J:211916
increased tumor necrosis factor secretion J:211916
Map3k7tm1Aki/Map3k7tm1Aki
Tg(Alb1-cre)7Gsc/0

(involves: 129P2/OlaHsd * FVB/N)
liver inflammation J:160521
Map3k7tm1Aki/Map3k7tm1Aki
Tg(Lck-cre)1Jtak/0

(involves: 129P2/OlaHsd)
abnormal spleen morphology J:112837
abnormal T cell activation J:112837
absent regulatory T cells J:112837
colitis J:112837
decreased CD4-positive, alpha-beta T cell number J:112837
decreased CD8-positive, alpha-beta T cell number J:112837
decreased single-positive T cell number J:112837
decreased T cell number J:112837
decreased T cell proliferation J:112837
enlarged lymph nodes J:112837
enlarged spleen J:112837
increased memory T cell number J:112837
spleen hyperplasia J:112837
Map3k7tm1Aki/Map3k7tm1Aki
Tg(Lck-cre)1Jtak/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal alpha-beta intraepithelial T cell morphology J:238318
abnormal CD4-positive, alpha-beta T cell physiology J:238318
abnormal cytokine level J:238318
abnormal intraepithelial T cell number J:238318
abnormal regulatory T cell number J:238318
abnormal regulatory T cell physiology J:238318
abnormal T cell morphology J:238318
colitis J:238318
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:238318
decreased NK T cell number J:238318
increased CD4-positive, alpha-beta T cell number J:238318
increased gamma-delta intraepithelial T cell number J:238318
increased interferon-gamma secretion J:238318
increased interleukin-17 secretion J:238318
Map3k7tm1Zjc/Map3k7tm1Zjc
Tg(Lck-cre)548Jxm/0

(involves: 129S7/SvEvBrd * C57BL/6 * CBA)
decreased CD4-positive, alpha-beta T cell number J:111794
decreased CD8-positive, alpha-beta T cell number J:111794
decreased T cell number J:111794
increased thymocyte apoptosis J:111794
Map3k8M1Btlr/Map3k8+
(C57BL/6J-Map3k8M1Btlr)
abnormal tumor necrosis factor secretion J:140986
decreased tumor necrosis factor secretion J:140986
Map3k8M1Btlr/Map3k8M1Btlr
(C57BL/6J-Map3k8M1Btlr)
abnormal response to infection J:140986
decreased interferon-alpha secretion J:140986
decreased interferon-beta secretion J:140986
decreased interleukin-1 beta secretion J:140986
decreased interleukin-6 secretion J:140986
decreased tumor necrosis factor secretion J:140986
impaired natural killer cell mediated cytotoxicity J:140986
increased interleukin-12b secretion J:140986
Map3k8m2Btlr/Map3k8m2Btlr
(C57BL/6J-Map3k8m2Btlr)
abnormal response to infection J:212899
Map3k8m3Btlr/Map3k8+
(C57BL/6J-Map3k8m3Btlr)
decreased macrophage cytokine production J:224668
decreased tumor necrosis factor secretion J:224668
Map3k8m3Btlr/Map3k8m3Btlr
(C57BL/6J-Map3k8m3Btlr)
decreased macrophage cytokine production J:224668
decreased tumor necrosis factor secretion J:224668
Map3k8M4Btlr/Map3k8+
(C57BL/6J-Map3k8M4Btlr)
decreased tumor necrosis factor secretion J:254880
Map3k8M4Btlr/Map3k8M4Btlr
(C57BL/6J-Map3k8M4Btlr)
decreased tumor necrosis factor secretion J:254880
Map3k8tm1.2Gkl/Map3k8tm1.2Gkl
(involves: 129 * C57BL/6J * FVB/N)
decreased tumor necrosis factor secretion J:193546
Map3k8tm1Pnt/Map3k8tm1Pnt
(involves: 129S1/Sv * C57BL/6J)
decreased susceptibility to endotoxin shock J:66503
decreased tumor necrosis factor secretion J:66503
immune system phenotype J:66503
Map3k8tm1Pnt/Map3k8tm1Pnt
(involves: 129S1/Sv)
immune system phenotype J:142340, J:196528
Map3k8tm1Pnt/Map3k8tm1Pnt
Nfkb1tm1Sley/Nfkb1tm1Sley

(involves: 129S1/Sv * 129S4/SvJae)
decreased circulating interleukin-12b level J:196528
decreased interleukin-12b secretion J:196528
decreased tumor necrosis factor secretion J:196528
Map3k8tm1Pnt/Map3k8tm1Pnt
Tnftm2Gkl/Tnf+

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J)
increased CD8-positive, alpha-beta T cell number J:108572
increased single-positive T cell number J:108572
small intestinal inflammation J:108572
Map3k8tm1Sley/Map3k8tm1Sley
Nfkb1tm1Sley/Nfkb1tm1Sley

(involves: 129S4/SvJae)
decreased tumor necrosis factor secretion J:196528
Map3k8tm1Tmat/Map3k8tm1Tmat
(involves: 129S/SvEv * C57BL/6)
abnormal cytokine secretion J:92844
abnormal dendritic cell antigen presentation J:92844
decreased IgE level J:92844
decreased IgG1 level J:92844
increased IgG2a level J:92844
increased T cell proliferation J:92844
Map3k9em1(IMPC)Mbp/Map3k9em1(IMPC)Mbp
(C57BL/6N-Map3k9em1(IMPC)Mbp/MbpMmucd)
increased neutrophil cell number J:211773
Map3k10tm1Dsd/Map3k10tm1Dsd
Map3k11tm1Rjd/Map3k11tm1Rjd

(involves: 129 * 129S6/SvEvTac * C57BL/6J)
abnormal circulating chemokine level J:177426
abnormal circulating cytokine level J:177426
abnormal response to infection J:177426
Map3k10tm1Dsd/Map3k10tm1Dsd
Map3k11tm2.1Rjd/Map3k11tm2.1Rjd

(involves: 129 * C57BL/6J)
abnormal circulating chemokine level J:177426
abnormal circulating cytokine level J:177426
abnormal response to infection J:177426
Map3k14aly/Map3k14+
RelbTg(H2-K1/GH1)106Bri/Relb+

(involves: C57BL/6 * C57BL/6J)
decreased circulating interferon-gamma level J:120659
decreased NK T cell number J:120659
decreased Peyer's patch number J:120659
small Peyer's patches J:120659
Map3k14aly/Map3k14aly
(involves: C57BL/6J)
abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology J:87993, J:128211
abnormal dendritic cell antigen presentation J:128211
abnormal dendritic cell physiology J:128211
abnormal immune system morphology J:147681
abnormal immune system physiology J:147681
abnormal NK T cell morphology J:120659
abnormal T cell activation J:38580
abnormal thymus corticomedullary boundary morphology J:87993
abnormal thymus medulla morphology J:87993
absent Peyer's patches J:120659
bile duct inflammation J:48224
decreased circulating interferon-gamma level J:120659
decreased circulating interleukin-4 level J:120659
decreased dendritic cell number J:128211
decreased IgE level J:135748
decreased mast cell number J:135748
decreased NK T cell number J:120659
decreased regulatory T cell number J:128211
increased eosinophil cell number J:135748
increased inflammatory response J:38580, J:48224
increased susceptibility to parasitic infection J:135748
kidney inflammation J:38580
lacrimal gland inflammation J:38580
liver inflammation J:48224
lung inflammation J:48224
pancreas inflammation J:48224
small thymus J:147681
thymus cyst J:147681
Map3k14aly/Map3k14aly
(involves: AEJ/GnRk * C57BL/6J)
abnormal immune system morphology J:54529
abnormal lymphocyte morphology J:16865
abnormal lymphopoiesis J:16865
abnormal spleen primary B follicle morphology J:54529
absent follicular dendritic cells J:54529
absent lymph nodes J:16865, J:54529
absent Peyer's patches J:16865, J:54529
absent spleen marginal zone J:54529
absent thymus corticomedullary boundary J:16865, J:54529
decreased B cell number J:54529
decreased IgA level J:16865, J:54529
decreased IgG level J:16865, J:54529
decreased IgM level J:16865, J:54529
decreased spleen B cell follicle number J:16865
increased length of allograft survival J:16865
Map3k14aly/Map3k14aly
(C57BL/6J-Map3k14aly)
absent lymph nodes J:16865
increased susceptibility to infection J:16865
Map3k14m1Btlr/Map3k14m1Btlr
(C57BL/6J-Map3k14m1Btlr)
abnormal B cell activation J:152065
absent lymph nodes J:152065
arrested B cell differentiation J:152065
decreased B cell number J:152065
decreased IgG level J:152065
Map3k14m1Btlr/Map3k14m1Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
arrested B cell differentiation J:185495
decreased IgG level J:185495
Map3k14tm1.1Gne/Map3k14tm1.1Gne
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NTac)
decreased B cell number J:280549
Map3k14tm1.1Gne/Map3k14tm1.1Gne
Otub1tm1c(EUCOMM)Hmgu/Otub1tm1c(EUCOMM)Hmgu
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * C57BL/6NTac)
immune system phenotype J:280549
Map3k14tm1.2Gne/Map3k14tm1.2Gne
(B6(Cg)-Map3k14tm1.2Gne)
abnormal B cell physiology J:240453
abnormal spleen marginal zone morphology J:240453
abnormal thymus cell ratio J:240453
absent inguinal lymph nodes J:240453
absent Peyer's patches J:240453
absent popliteal lymph nodes J:240453
decreased B cell number J:240453
decreased B-2 B cell number J:240453
decreased follicular B cell number J:240453
decreased germinal center B cell number J:240453
decreased IgA level J:240453
decreased marginal zone B cell number J:240453
decreased transitional stage T1 B cell number J:240453
decreased transitional stage T2 B cell number J:240453
small axillary lymph nodes J:240453
small brachial lymph nodes J:240453
Map3k14tm1Rds/Map3k14tm1Rds
(involves: 129/Sv * C57BL/6)
abnormal spleen morphology J:68125
abnormal thymus morphology J:68125
absent axillary lymph nodes J:68125
absent cervical lymph nodes J:68125
absent inguinal lymph nodes J:68125
absent lymph nodes J:68125
absent mesenteric lymph nodes J:68125
absent Peyer's patches J:68125
absent popliteal lymph nodes J:68125
decreased IgA level J:68125
decreased IgG2b level J:68125
decreased immunoglobulin level J:68125
Map3k14tm1Rds/Map3k14tm1Rds
(involves: 129)
abnormal class switch recombination J:188560
Map4k1m1Anu/Map4k1m1Anu
(C57BL/6NCrlAnu-Map4k1m1Anu)
immune system phenotype J:104190
Map4k1tm1Ssaw/Map4k1tm1Ssaw
(B6.Cg-Map4k1tm1Ssaw)
abnormal dendritic cell antigen presentation J:150295
abnormal dendritic cell physiology J:150295
increased interleukin-1 beta secretion J:150295
increased interleukin-6 secretion J:150295
increased interleukin-12 secretion J:150295
increased tumor necrosis factor secretion J:150295
Map4k1tm1Tht/Map4k1tm1Tht
(B6.129S7-Map4k1tm1Tht)
increased susceptibility to experimental autoimmune encephalomyelitis J:116613
Map4k1tm1Tht/Map4k1tm1Tht
(involves: 129S7/SvEvBrd)
abnormal cytokine secretion J:116613
abnormal humoral immune response J:116613
increased T cell proliferation J:116613
Map4k3Gt(RRO270)Byg/Map4k3Gt(RRO270)Byg
(involves: 129P2/OlaHsd)
abnormal interleukin secretion J:177642
abnormal T-helper 1 cell differentiation J:177642
abnormal T-helper 2 cell differentiation J:177642
abnormal T-helper 17 cell differentiation J:177642
decreased IgG1 level J:177642
decreased IgG2a level J:177642
decreased IgG2b level J:177642
decreased IgG3 level J:177642
decreased IgM level J:177642
decreased immunoglobulin level J:177642
decreased interferon-gamma secretion J:177642
decreased interleukin-2 secretion J:177642
decreased interleukin-4 secretion J:177642
decreased interleukin-17 secretion J:177642
decreased susceptibility to experimental autoimmune encephalomyelitis J:177642
decreased T cell proliferation J:177642
immune system phenotype J:177642
Map4k5Gt(OST218153)Lex/Map4k5Gt(OST218153)Lex
(B6;129S5-Map4k5Gt(OST218153)Lex/Ieg)
increased CD4-positive, alpha-beta T cell number J:82809
increased IgG1 level J:82809
Map7mshi/Map7mshi
(involves: BALB/cBy)
decreased length of allograft survival J:37165
Mapk1tm1.1Hed/Mapk1tm1.1Hed
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal T cell subpopulation ratio J:113280
decreased CD4-positive, alpha-beta T cell number J:113280
decreased CD8-positive, alpha-beta T cell number J:113280
Mapk1tm1Gela/Mapk1tm1Gela
H2az2Tg(Wnt1-cre)11Rth/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J)
abnormal thymus morphology J:144862
Mapk1tm1Gela/Mapk1tm1Gela
Mapk3tm1Gela/Mapk3+
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J)
abnormal thymus morphology J:144862
Mapk1tm1Gela/Mapk1tm1Gela
Mapk3tm1Gela/Mapk3tm1Gela
H2az2Tg(Wnt1-cre)11Rth/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J)
athymia J:144862
Mapk1tm1Hed/Mapk1tm1Hed
Mapk3tm1Gpg/Mapk3tm1Gpg
Tg(Cd4-cre)1Cwi/0

(involves: 129/Sv * C57BL/6 * DBA/2)
abnormal positive T cell selection J:113280
Mapk1tm1Hed/Mapk1tm1Hed
Mapk3tm1Gpg/Mapk3tm1Gpg
Tg(Cd4-cre)1Cwi/0
Tg(TcrAND)53Hed/0

(involves: 129/Sv * C57BL/6 * DBA/2 * SJL)
abnormal positive T cell selection J:113280
abnormal T cell subpopulation ratio J:113280
Mapk1tm1Hed/Mapk1tm1Hed
Mapk3tm1Gpg/Mapk3tm1Gpg
Tg(Lck-cre)1Cwi/0

(involves: 129/Sv * C57BL/6 * DBA/2)
abnormal T cell proliferation J:113280
decreased thymocyte number J:113280
increased double-positive T cell number J:113280
small thymus J:113280
Mapk1tm1Hed/Mapk1tm1Hed
Mapk3tm1Gpg/Mapk3tm1Gpg
Tg(TcraTcrb)1100Mjb/0

(involves: 129/Sv * C57BL/6)
decreased thymocyte number J:113280
Mapk1tm1Hed/Mapk1tm1Hed
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal positive T cell selection J:113280
decreased CD4-positive, alpha-beta T cell number J:113280
decreased CD8-positive, alpha-beta T cell number J:113280
increased double-positive T cell number J:113280
Mapk1tm1Hed/Mapk1tm1Hed
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal T cell subpopulation ratio J:113280
decreased double-positive T cell number J:113280
decreased T cell proliferation J:113280
Mapk1tm1Hed/Mapk1tm1Hed
Tg(Lck-cre)1Cwi/0
Tg(TcrAND)53Hed/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal positive T cell selection J:113280
abnormal T cell subpopulation ratio J:113280
Mapk1tm1Hed/Mapk1tm1Hed
Tg(TcrAND)53Hed/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal double-positive T cell morphology J:113280
abnormal positive T cell selection J:113280
Mapk1tm1Hed/Mapk1tm1Hed
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6)
decreased thymocyte number J:113280
Mapk1tm2Moga/Mapk1tm2Moga
Mapk3tm1Gpg/Mapk3tm1Gpg
Tg(Mx1-cre)1Cgn/?

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * CBA)
abnormal pro-B cell differentiation J:134528
abnormal pro-B cell morphology J:134528
decreased pre-B cell number J:134528
Mapk3m1Btlr/Mapk3m1Btlr
(C57BL/6J-Mapk3m1Btlr)
decreased interleukin-1 beta secretion J:221481
Mapk3tm1Gela/Mapk3tm1Gela
(either: 129(Cg)-Mapk3tm1Gela or B6.129-Mapk3tm1Gela)
abnormal cytokine secretion J:107504
increased susceptibility to experimental autoimmune encephalomyelitis J:107504
Mapk3tm1Gpg/Mapk3tm1Gpg
(involves: 129)
decreased T cell number J:58468
decreased T cell proliferation J:58468
Mapk8tm1Flv/Mapk8tm1Flv
(involves: 129S1/Sv)
abnormal cytokine secretion J:51510
abnormal T-helper 1 cell differentiation J:51510
increased T cell proliferation J:51510
Mapk8tm1Rjd/Mapk8tm1Rjd
Mapk9tm2.1Rjd/Mapk9tm2.1Rjd
Lyz2tm1(cre)Ifo/Lyz2+

(B6J.Cg-Lyz2tm1(cre)Ifo Mapk9tm2.1Rjd Mapk8tm1Rjd)
abnormal chemokine level J:192551
abnormal circulating chemokine level J:192551
abnormal circulating cytokine level J:192551
abnormal macrophage differentiation J:192551
abnormal macrophage physiology J:192551
decreased inflammatory response J:192551
decreased macrophage cell number J:192551
decreased macrophage cytokine production J:192551
impaired macrophage chemotaxis J:192551
Mapk8tm1Wag/Mapk8+
Mapk9tm1Mka/Mapk9+

(involves: 129)
abnormal T cell activation J:78190
decreased T cell apoptosis J:78190
decreased T cell proliferation J:78190
Mapk8tm1Wag/Mapk8+
Mapk9tm1Mka/Mapk9tm1Mka

(involves: 129)
abnormal T cell activation J:78190
decreased T cell apoptosis J:78190
decreased T cell proliferation J:78190
Mapk8tm1Wag/Mapk8tm1Wag
(involves: 129P2/OlaHsd)
abnormal T cell activation J:78190
decreased T cell apoptosis J:78190
decreased T cell proliferation J:78190
Mapk8tm1Wag/Mapk8tm1Wag
Mapk9tm1Mka/Mapk9+

(involves: 129)
abnormal T cell activation J:78190
decreased T cell apoptosis J:78190
decreased T cell proliferation J:78190
Mapk9tm1Flv/Mapk9tm1Flv
(involves: 129S2/SvPas)
abnormal T-helper 1 cell differentiation J:50628
Mapk9tm1Flv/Mapk9tm1Flv
Tnftm2Gkl/Tnf+

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J)
immune system phenotype J:108572
small intestinal inflammation J:108572
Mapk9tm1Mka/Mapk9tm1Mka
(either: (involves: 129S2/SvPas) or (involves: 129S1/Sv * 129X1/SvJ))
abnormal T cell activation J:78129
decreased T cell apoptosis J:78129
decreased T cell proliferation J:78129
Mapk11tm1Jda/Mapk11tm1Jda
(B6.Cg-Mapk11tm1Jda)
immune system phenotype J:165966
Mapk11tm1Jda/Mapk11tm1Jda
Mapk14tm1Jda/Mapk14tm1Jda

(involves: 129 * C57BL/6)
abnormal T-helper 1 cell differentiation J:165966
abnormal T-helper 2 cell differentiation J:165966
abnormal T-helper 17 cell differentiation J:165966
decreased interferon-gamma secretion J:165966
decreased susceptibility to experimental autoimmune encephalomyelitis J:165966
decreased susceptibility to induced arthritis J:165966
decreased T cell proliferation J:165966
decreased tumor necrosis factor secretion J:165966
increased interleukin-10 secretion J:165966
Mapk11tm1Jsca/Mapk11tm1Jsca
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:107771
Mapk11tm1Jsca/Mapk11tm1Jsca
Tnftm2Gkl/Tnf+

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
arthritis J:107771
ileum inflammation J:107771
Mapk14tm1Jda/Mapk14tm1Jda
(B6.Cg-Mapk14tm1Jda)
abnormal T-helper 1 physiology J:146088
decreased interferon-alpha secretion J:146088
decreased interferon-gamma secretion J:146088
decreased T cell proliferation J:146088
increased double-negative T cell number J:146088
Mapkapk2tm1.2Gkl/Mapkapk2tm1.2Gkl
(involves: BALB/cJ * C57BL/6)
decreased circulating tumor necrosis factor level J:262876
decreased tumor necrosis factor secretion J:262876
Mapkapk2tm1b(EUCOMM)Hmgu/Mapkapk2tm1b(EUCOMM)Hmgu
(C57BL/6N-Mapkapk2tm1b(EUCOMM)Hmgu/H)
increased eosinophil cell number J:211773
increased large unstained cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Mapkapk2tm1Mgl/Mapkapk2tm1Mgl
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal cytokine level J:59678
abnormal macrophage derived foam cell morphology J:142788
decreased circulating tumor necrosis factor level J:59678
decreased susceptibility to endotoxin shock J:59678
increased spleen germinal center size J:59678
Mapkapk2tm1Mgl/Mapkapk2tm1Mgl
(involves: 129S * C57BL/6)
decreased interferon-gamma secretion J:76161
decreased tumor necrosis factor secretion J:76161
impaired macrophage phagocytosis J:76161
increased interleukin-1 beta secretion J:76161
increased susceptibility to bacterial infection J:76161
increased susceptibility to bacterial infection induced morbidity/mortality J:76161
Mapkapk2tm1Mgl/Mapkapk2tm1Mgl
(involves: 129P2/OlaHsd * 129S/SvEvBrd * C57BL/6)
abnormal cytokine secretion J:117668
Mapkapk2tm1Mgl/Mapkapk2tm1Mgl
Mapkapk3tm1.1Lex/Mapkapk3tm1.1Lex

(involves: 129P2/OlaHsd * 129S/SvEvBrd * C57BL/6)
abnormal cytokine secretion J:117668
Mapkapk2tm1Mgl/Mapkapk2tm1Mgl
Tnftm2Gkl/Tnf+

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J)
granulomatous inflammation J:108572
immune system phenotype J:108572
small intestinal inflammation J:108572
Mapkapk3em1(IMPC)Ccpcz/Mapkapk3em1(IMPC)Ccpcz
(C57BL/6N-Mapkapk3em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Mapkapk3tm1.1Lex/Mapkapk3tm1.1Lex
(involves: 129S/SvEvBrd * C57BL/6)
immune system phenotype J:117668
Mapkbp1tm1b(EUCOMM)Hmgu/Mapkbp1tm1b(EUCOMM)Hmgu
(C57BL/6N-Mapkbp1tm1b(EUCOMM)Hmgu/H)
increased spleen weight J:211773
Mapttm1(EGFP)Klt/Mapttm1(EGFP)Klt
Tg(MAPT)8cPdav/?

(involves: 129S4/SvJae * C57BL/6 * Swiss Webster)
abnormal spleen B cell follicle morphology J:174270
abnormal spleen B cell follicle shape J:174270
abnormal spleen red pulp morphology J:174270
increased spleen B cell follicle size J:174270
Mapttm2.1(FUS)Neas/Mapt+
(B6J.129P2(129S)-Mapttm2.1(FUS)Neas)
microgliosis J:232167
Mapttm3.1(FUS)Neas/Mapt+
(B6J.129P2(129S)-Mapttm3.1(FUS)Neas)
microgliosis J:232167
Mar1tm1Wtg/Mar1+
(involves: 129S6/SvEvTac * C57BL/6)
abnormal immune system physiology J:68024
abnormal somatic hypermutation frequency J:68024
Mar1tm1Wtg/Mar1tm1Wtg
(involves: 129S6/SvEvTac * C57BL/6)
abnormal somatic hypermutation frequency J:68024
Marchf1tm1.1Sish/Marchf1tm1.1Sish
(involves: 129S1/Sv * 129X1/SvJ)
abnormal B cell physiology J:119918
abnormal dendritic cell antigen presentation J:201198, J:157516
abnormal dendritic cell morphology J:119918
abnormal level of surface class II molecules J:119918
abnormal T cell differentiation J:201198
decreased interleukin-12 secretion J:157516
decreased regulatory T cell number J:201198
decreased tumor necrosis factor secretion J:157516
immune system phenotype J:201198
Marchf2em1Cnu/Marchf2em1Cnu
(C57BL/6-Marchf2em1Cnu)
decreased susceptibility to bacterial infection J:297482
decreased susceptibility to viral infection J:297482
increased circulating interferon-beta level J:297482
increased circulating interleukin-6 level J:297482
increased circulating interleukin-12 level J:297482
increased circulating tumor necrosis factor level J:297482
increased interleukin-6 secretion J:297482
increased interleukin-12 secretion J:297482
increased susceptibility to bacterial infection induced morbidity/mortality J:297482
increased susceptibility to endotoxin shock J:297482
Marchf3em1Hbsh/Marchf3em1Hbsh
(involves: C57BL/6J)
abnormal circulating cytokine level J:267641
increased susceptibility to infection induced morbidity/mortality J:267641
Marchf3tm1b(EUCOMM)Hmgu/Marchf3tm1b(EUCOMM)Hmgu
(C57BL/6N-Marchf3tm1b(EUCOMM)Hmgu/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Marchf5tm1.1Ygi/Marchf5tm1.1Ygi
Tg(Emx1-cre)#Ito/0

(involves: C57BL/6)
increased microglial cell activation J:284572
Marchf5tm1a(EUCOMM)Wtsi/Marchf5+
(C57BL/6-Marchf5tm1a(EUCOMM)Wtsi)
decreased susceptibility to Riboviria infection induced morbidity/mortality J:225000
increased circulating interferon-beta level J:225000
increased circulating interleukin-6 level J:225000
Marchf7Gt(ROSABetageo)1Summ/Marchf7+
(involves: BALB/c)
abnormal cytokine secretion J:96167
abnormal interleukin level J:96167
increased interleukin-10 secretion J:96167
increased T cell proliferation J:96167
Marchf7Gt(ROSABetageo)1Summ/Marchf7Gt(ROSABetageo)1Summ
(involves: BALB/c)
abnormal cytokine secretion J:96167
abnormal interleukin level J:96167
increased interleukin-10 secretion J:96167
increased T cell proliferation J:96167
Marchf8em2(IMPC)Ccpcz/Marchf8em2(IMPC)Ccpcz
(C57BL/6N-Marchf8em2(IMPC)Ccpcz/Ccpcz)
decreased eosinophil cell number J:211773
Marchf8tm1.1Lkle/Marchf8tm1.1Lkle
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:236611
Marchf9tm1a(EUCOMM)Wtsi/Marchf9tm1a(EUCOMM)Wtsi
(Not Specified)
decreased B cell number J:165965
Marcksl1tm1Fsh/Marcksl1tm1Fsh
(involves: 129S4/SvJae)
abnormal macrophage physiology J:115146
Marcotm1Ktry/Marcotm1Ktry
(B6.129S6-Marcotm1Ktry)
abnormal macrophage physiology J:115081
abnormal spleen marginal zone morphology J:122271
impaired macrophage phagocytosis J:115081
increased inflammatory response J:115081
increased susceptibility to bacterial infection J:115081, J:122271
Marcotm1Ktry/Marcotm1Ktry
Msr1tm1Csk/Msr1tm1Csk

(B6.129-Marcotm1Ktry Msr1tm1Csk)
abnormal macrophage physiology J:122271
abnormal spleen marginal zone morphology J:122271
increased IgM level J:122271
increased susceptibility to bacterial infection J:122271
Marcotm1Spt/Marcotm1Spt
(C57BL/6-Marcotm1Spt)
abnormal dendritic cell chemotaxis J:204315
abnormal dendritic cell physiology J:204315
increased interferon-gamma secretion J:204315
Marif1C57BL/10J/Marif1C57BL/10J
(involves: O20/A * NXT-10/Dem)
abnormal immune serum protein physiology J:90251
decreased interleukin-12 secretion J:90251
decreased tumor necrosis factor secretion J:90251
Marif2C57BL/10J/Marif2C57BL/10J
(involves: O20/A * NXT-10/Dem)
abnormal immune serum protein physiology J:90251
decreased interleukin-12 secretion J:90251
increased tumor necrosis factor secretion J:90251
Marif3C57BL/10J/Marif3C57BL/10J
(involves: O20/A * NXT-10/Dem)
increased interleukin-12 secretion J:90251
Mark2tm1Hpw/Mark2tm1Hpw
(involves: 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:68830
abnormal humoral immune response J:68830
abnormal immune system physiology J:68830
abnormal spleen B cell follicle morphology J:68830
decreased B cell proliferation J:68830
decreased IgG3 level J:68830
decreased IgM level J:68830
enlarged lymph nodes J:68830
enlarged spleen J:68830
glomerulonephritis J:68830
increased B cell number J:68830
increased B cell proliferation J:68830
increased interferon-gamma secretion J:68830
increased interleukin-4 secretion J:68830
increased spleen weight J:68830
kidney inflammation J:68830
lung inflammation J:68830
lymph node hyperplasia J:68830
salivary gland inflammation J:68830
spleen hyperplasia J:68830
Mark4em1(IMPC)Mbp/Mark4em1(IMPC)Mbp
(C57BL/6N-Mark4em1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Marveld2tm1.1Sria/Marveld2tm1.1Sria
(involves: 129X1/SvJ * C57BL/6J)
increased spleen weight J:201580
Marveld3em1(IMPC)Ccpcz/Marveld3em1(IMPC)Ccpcz
(C57BL/6NCrl-Marveld3em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Masp1tm1Tefu/Masp1tm1Tefu
(B6.129S4-Masp1tm1Tefu)
impaired complement alternative pathway J:177350
impaired lectin complement pathway J:134537
Masp2tm1Tefu/Masp2tm1Tefu
(involves: 129 * C57BL/6)
abnormal complement pathway J:140667
Masp2tm1Wjsc/Masp2tm1Wjsc
(B6.129P2-Masp2tm1Wjsc)
impaired lectin complement pathway J:172218
Mast4m1Anu/Mast4m1Anu
(C57BL/6NCrlAnu-Mast4m1Anu)
immune system phenotype J:104190
Mat1atm1Jmm/Mat1atm1Jmm
(involves: 129/Sv * C57BL/6)
liver inflammation J:69408
Matn1tm1Ref/Matn1tm1Ref
Matn2tm1Asz/Matn2tm1Asz
Matn3tm1Asz/Matn3tm1Asz
Matn4tm1.1Asz/Matn4tm1.1Asz

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased double-positive T cell number J:237230
increased granulocyte number J:237230
Matn3tm1Brd/Matn3tm1Brd
(involves: 129S7/SvEvBrd * C57BL/6)
osteoarthritis J:112002
Matr3em1Tcp/Matr3em1Tcp
(C57BL/6J-Matr3em1Tcp)
increased microglial cell activation J:298091
Mavstm1Aki/Mavstm1Aki
(Not Specified)
abnormal cytokine secretion J:124405
abnormal response to infection J:124405
decreased circulating interleukin-6 level J:124405
decreased interferon-alpha secretion J:124405
decreased interferon-beta secretion J:124405
decreased interleukin-6 secretion J:124405
increased susceptibility to Picornaviridae infection J:124405
Mavstm1Aki/Mavstm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:130954
decreased circulating interferon-alpha level J:130954
decreased circulating interferon-beta level J:130954
decreased circulating interferon-gamma level J:130954
decreased circulating interleukin-6 level J:130954
decreased IgG1 level J:130954
decreased IgG2a level J:130954
decreased IgG level J:130954
decreased interferon-beta secretion J:130954
decreased interleukin-12b secretion J:130954
Mavstm1Aki/Mavstm1Aki
(involves: C57BL/6)
immune system phenotype J:132662
Mavstm1Aki/Mavstm1Aki
(involves: 129S/SvEv * C57BL/6)
abnormal circulating interferon level J:162888
abnormal dendritic cell physiology J:162888
abnormal macrophage physiology J:162888
brain inflammation J:162888
CNS inflammation J:162888
decreased CD4-positive, alpha-beta T cell number J:162888
decreased CD8-positive, alpha-beta T cell number J:162888
decreased interferon-beta secretion J:162888
enlarged spleen J:162888
immune system phenotype J:162888
increased circulating interferon-gamma level J:162888
increased circulating interleukin-6 level J:162888
increased circulating tumor necrosis factor level J:162888
increased dendritic cell number J:162888
increased IgG2a level J:162888
increased IgG level J:162888
increased IgM level J:162888
increased susceptibility to Flaviviridae infection J:162888
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:162888
Mavstm1Aki/Mavstm1Aki
Ifna6tm1Aki/Ifna6+

(involves: 129P2/OlaHsd)
abnormal alveolar macrophage morphology J:124340
abnormal macrophage morphology J:124340
abnormal myeloid dendritic cell morphology J:124340
decreased interferon-alpha secretion J:124340
Mavstm1Aki/Mavstm1Aki
Ticam1tm1Aki/Ticam1tm1Aki

(involves: 129P2/OlaHsd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:130954
decreased circulating interferon-alpha level J:130954
decreased circulating interferon-beta level J:130954
decreased circulating interferon-gamma level J:130954
decreased circulating interleukin-6 level J:130954
decreased circulating interleukin-12b level J:130954
decreased cytotoxic T cell cytolysis J:130954
decreased IgG1 level J:130954
decreased IgG2a level J:130954
decreased IgG level J:130954
decreased interferon-beta secretion J:130954
decreased interleukin-12b secretion J:130954
Mavstm1Camb/Mavstm1Camb
(involves: 129S6/SvEvTac * C57BL/6)
abnormal B cell physiology J:180356
decreased B cell proliferation J:180356
decreased interleukin-12 secretion J:180356
decreased tumor necrosis factor secretion J:180356
Mavstm1Itl/Mavstm1Itl
Trex1tm1Tld/Trex1tm1Tld

(involves: 129P2/OlaHsd * C57BL/6)
increased inflammatory response J:181257
myocarditis J:181257
myositis J:181257
skin inflammation J:181257
stomach inflammation J:181257
Mavstm1Tsc/Mavstm1Tsc
(Not Specified)
decreased interferon-beta secretion J:136289
Mavstm1Tsse/Mavstm1Tsse
Tg(PVR)1Kkst/0

(involves: 129 * C57BL/6 * ICR)
abnormal interferon-alpha secretion J:179625
decreased susceptibility to Picornaviridae infection induced morbidity/mortality J:179625
Mavstm1Zjc/Mavs+
(involves: 129/Sv * C57BL/6)
abnormal innate immunity J:110905
increased susceptibility to Riboviria infection J:110905
Mavstm1Zjc/Mavstm1Zjc
(involves: 129/Sv * C57BL/6)
abnormal dendritic cell physiology J:110905
abnormal innate immunity J:110905
abnormal macrophage physiology J:110905
increased susceptibility to Riboviria infection J:110905
Mavstm1Zjc/Mavstm1Zjc
(B6.Cg-Mavstm1Zjc)
abnormal circulating interferon level J:243916
Mavstm1Zjc/Mavstm1Zjc
Rnaseh2atm1Crh/Rnaseh2atm1Crh

(Not Specified)
abnormal innate immunity J:232933
Mb21d2em1(IMPC)Mbp/Mb21d2em1(IMPC)Mbp
(C57BL/6N-Mb21d2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
Mbd2tm1Bh/Mbd2tm1Bh
(NOD.129P2(B6)-Mbd2tm1Bh)
abnormal CD4-positive, alpha-beta T cell physiology J:323838
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:323838
abnormal effector T cell morphology J:323838
enlarged lymph nodes J:323838
enlarged spleen J:323838
increased T cell proliferation J:323838
increased T-helper 1 cell number J:323838
increased T-helper 2 cell number J:323838
insulitis J:323838
salivary gland inflammation J:323838
Mbd3tm2Bh/Mbd3tm2Bh
Tg(Vil1-cre)20Syr/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
increased susceptibility to induced colitis J:167984
Mbd5tm1b(EUCOMM)Wtsi/Mbd5+
(C57BL/6N-Mbd5tm1b(EUCOMM)Wtsi/Ics)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
Mbipem1(IMPC)J/Mbip+
(C57BL/6NJ-Mbipem1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Mbis1NOD/ShiLt/Mbis1NOD/ShiLt
(involves: BALB/c * NOD/Lt)
increased susceptibility to bacterial infection J:75276
Mbis2BALB/c/Mbis2BALB/c
(involves: BALB/c * NOD/Lt)
increased susceptibility to bacterial infection J:75276
Mbis2BALB/c/Mbis2NOD/ShiLt
(involves: BALB/c * NOD/Lt)
increased susceptibility to bacterial infection J:75276
Mbis3BALB/c/?
(involves: BALB/c * NOD/Lt)
increased susceptibility to bacterial infection J:75276
Mbis4NOD/ShiLt/Mbis4NOD/ShiLt
(involves: BALB/c * NOD/Lt)
increased susceptibility to bacterial infection J:75276
Mbl1tm1.1Mnz/Mbl1tm1.1Mnz
(B6.129-Mbl1tm1.1Mnz)
immune system phenotype J:84540
Mbl1tm1Kata/Mbl1tm1Kata
(involves: 129S4/SvJae * C57BL/6J)
decreased circulating tumor necrosis factor level J:90437
Mbl1tm1Kata/Mbl1tm1Kata
Mbl2tm1Kata/Mbl2tm1Kata

(involves: 129 * C57BL/6)
abnormal B cell number J:97686
abnormal circulating interleukin-6 level J:98124
abnormal circulating tumor necrosis factor level J:98124
decreased germinal center B cell number J:97686
decreased macrophage cell number J:98124
decreased monocyte cell number J:98124
impaired macrophage phagocytosis J:97686, J:98124
increased B-1 B cell number J:97686
increased susceptibility to bacterial infection J:98124
Mbl1tm1Kata/Mbl1tm1Kata
Mbl2tm1Kata/Mbl2tm1Kata

(involves: 129 * C57BL/6J)
abnormal complement pathway J:106351
abnormal response to infection J:106352
increased susceptibility to bacterial infection J:106353
Mbl1tm1Rala/Mbl1tm1Rala
(involves: 129X1/SvJ * C57BL/6J)
abnormal immunoglobulin level J:145279
decreased IgG2b level J:145279
decreased IgM level J:145279
increased IgG1 level J:145279
increased IgG2a level J:145279
increased IgG3 level J:145279
increased susceptibility to parasitic infection J:145279
Mboat2em1(IMPC)Mbp/Mboat2em1(IMPC)Mbp
(C57BL/6N-Mboat2em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Mboat7tm1b(KOMP)Wtsi/Mboat7+
(C57BL/6N-Mboat7tm1b(KOMP)Wtsi/H)
increased lymphocyte cell number J:211773
Mbpshi/Mbpshi
(C3Fe.SWV-Mbpshi/J)
decreased susceptibility to Picornaviridae infection J:41447
immune system phenotype J:41447
Mbpshi/Mbpshi
(involves: BALB/c * C3HeB/Fe * SWV)
increased interferon-gamma secretion J:48412
increased interleukin-2 secretion J:48412
increased interleukin-4 secretion J:48412
increased susceptibility to experimental autoimmune encephalomyelitis J:48412
increased T cell proliferation J:48412
Mbtps1wrt/Mbtps1wrt
(C57BL/6J-Mbtps1wrt)
decreased cytotoxic T cell cytolysis J:94077
decreased susceptibility to bacterial infection J:123123
increased interleukin-1 beta secretion J:146454
increased interleukin-6 secretion J:146454
increased susceptibility to Herpesvirales infection J:94077, J:123123
increased susceptibility to induced colitis J:146454
Mc2rtm1Dchi/Mc2rtm1Dchi
(B6.129P2-Mc2rtm1Dchi)
increased spleen weight J:127445
increased thymus weight J:127445
Mc3rtm1Butl/Mc3rtm1Butl
(B6.Cg-Mc3rtm1Butl)
increased inflammatory response J:178147
Mc4rtm1Dhu/Mc4rtm1Dhu
(involves: 129S4/SvJae * C57BL/6J)
decreased osteoclast cell number J:97566
Mc4rtm1Lowl/Mc4rtm1Lowl
(involves: 129S4/SvJae * C57BL/6J)
increased circulating interleukin-6 level J:177386
liver inflammation J:177386
white adipose tissue inflammation J:177386
Mc4rtm1Matsu/Mc4rtm1Matsu
(C57BL/6J-Mc4rtm1Matsu)
liver inflammation J:285412
Mc5rem1(IMPC)Mbp/Mc5rem1(IMPC)Mbp
(C57BL/6NCrl-Mc5rem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Mcamtm1Lex/Mcamtm1Lex
(involves: 129S/SvEvBrd)
abnormal cytokine level J:193167
abnormal response to infection J:193167
decreased macrophage cytokine production J:193167
Mcattm1.1Ssmi/Mcattm1.1Ssmi
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA)
abnormal immune system organ morphology J:192213
abnormal myelopoiesis J:192213
decreased leukocyte cell number J:192213
decreased lymphocyte cell number J:192213
enlarged spleen J:192213
Mcemp1em1Jngj/Mcemp1em1Jngj
(C57BL/6-Mcemp1em1Jngj)
abnormal mast cell differentiation J:335318
abnormal type I hypersensitivity reaction J:335318
Mcidasem2(IMPC)Tcp/Mcidasem2(IMPC)Tcp
(C57BL/6NCrl-Mcidasem2(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
increased leukocyte cell number J:211773
Mcl1em1(IMPC)Mbp/Mcl1+
(C57BL/6N-Mcl1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
small spleen J:211773
Mcl1tm1Dmta/Mcl1+
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(B6.Cg-Mcl1tm1Dmta Gt(ROSA)26Sortm9(cre/ESR1)Arte)
decreased germinal center B cell number J:166069
decreased memory B cell number J:166069
Mcl1tm1Dmta/Mcl1+
Tg(Aicda-cre)9Mbu/0

(B6.Cg-Mcl1tm1Dmta Tg(Aicda-cre)9Mbu)
decreased germinal center B cell number J:166069
decreased memory B cell number J:166069
Mcl1tm1Dmta/Mcl1tm1Dmta
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(B6.Cg-Mcl1tm1Dmta Gt(ROSA)26Sortm9(cre/ESR1)Arte)
abnormal B cell differentiation J:166069
absent germinal center B cells J:166069
absent memory B cells J:166069
decreased naive B cell number J:166069
Mcl1tm1Dmta/Mcl1tm1Dmta
Tg(Aicda-cre)9Mbu/0

(B6.Cg-Mcl1tm1Dmta Tg(Aicda-cre)9Mbu)
absent germinal center B cells J:166069
absent memory B cells J:166069
decreased IgG1 level J:166069
immune system phenotype J:166069
Mcl1tm1Yen/Mcl1tm1Yen
(B6.129-Mcl1tm1Yen)
abnormal CD8-positive, alpha-beta T cell physiology J:146246
abnormal double-positive T cell morphology J:146246
decreased CD8-positive, alpha-beta T cell number J:146246
decreased double-negative T cell number J:146246
decreased single-positive T cell number J:146246
Mcl1tm1Yen/Mcl1tm1Yen
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal double-positive T cell morphology J:146246
decreased CD8-positive, alpha-beta T cell number J:146246
Mcl1tm1Yen/Mcl1tm1Yen
Tg(TcraTcrb)425Cbn/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal double-positive T cell morphology J:146246
decreased CD4-positive, alpha-beta T cell number J:146246
Mcl1tm1Ywh/Mcl1tm1Ywh
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
abnormal neutrophil physiology J:137502
decreased granulocyte number J:137502
decreased neutrophil cell number J:137502
immune system phenotype J:137502
impaired neutrophil recruitment J:137502
increased eosinophil cell number J:137502
Mcl1tm1Ywh/Mcl1tm1Ywh
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:137400
decreased CD8-positive, alpha-beta T cell number J:137400
decreased T cell number J:137400
increased double-positive T cell number J:137400
increased T cell apoptosis J:137400
Mcl1tm1Ywh/Mcl1tm1Ywh
Tg(Lck-cre)548Jxm/0

(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * CBA)
abnormal T cell differentiation J:137400
decreased CD4-positive, alpha-beta T cell number J:137400
decreased CD8-positive, alpha-beta T cell number J:137400
decreased double-negative T cell number J:137400
decreased double-positive T cell number J:137400
decreased T cell number J:137400
increased T cell apoptosis J:137400
thymus hypoplasia J:137400
Mcl1tm2Sjk/Mcl1tm3Sjk
Tg(Lck-cre)1Cwi/0

(involves: 129X1/SvJ * C57BL/6 * DBA/2)
arrested T cell differentiation J:86906
decreased double-negative T cell number J:86906
decreased double-positive T cell number J:86906
decreased T cell number J:86906
decreased thymocyte number J:86906
increased T cell apoptosis J:86906
Mcl1tm2Sjk/Mcl1tm3Sjk
Tg(Mx1-cre)1Cgn/0

(involves: 129X1/SvJ * C57BL/6 * CBA)
decreased B cell number J:86906
decreased T cell number J:86906
Mcl1tm3Sjk/Mcl1tm3Sjk
Tg(Cpa3-cre)3Glli/0

(involves: 129X1/Sv * C57BL/6)
decreased basophil cell number J:179080
decreased inflammatory response J:179080
decreased mast cell number J:179080
decreased susceptibility to type I hypersensitivity reaction J:179080
Mcm2tm1(cre/ERT2)Scpr/Mcm2tm1(cre/ERT2)Scpr
(involves: 129S6/SvEvTac)
enlarged spleen J:141493
Mcm3aptm1Imku/Mcm3aptm1Imku
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal germinal center B cell physiology J:88276
abnormal memory B cell number J:88276
abnormal spleen germinal center morphology J:88276
decreased B cell number J:88276
decreased B cell proliferation J:88276
decreased germinal center B cell number J:88276
decreased IgG level J:88276
Mcm4Sdla/Mcm4+
(involves: C57BL/6)
decreased DN1 thymic pro-T cell number J:194117
enlarged lymph nodes J:194117
enlarged spleen J:194117
Mcoln1tm1Sasl/Mcoln1tm1Sasl
(involves: 129S6/SvEvTac * C57BL/6)
abnormal macrophage physiology J:189070
Mcoln2tm1e.1(KOMP)Wtsi/Mcoln2tm1e.1(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
abnormal chemokine level J:239875
abnormal chemokine secretion J:239875
abnormal innate immunity J:239875
impaired macrophage chemotaxis J:239875
impaired neutrophil chemotaxis J:239875
Mcph1Tg(HLA-A2.1)1Enge/Mcph1+
(involves: C57BL/6)
abnormal immune tolerance J:52612
Mcph1Tg(HLA-A2.1)1Enge/Mcph1+
(NOD.B6-Mcph1Tg(HLA-A2.1)1Enge)
increased susceptibility to autoimmune diabetes J:109851
Mcph1Tg(HLA-A2.1)1Enge/Mcph1Tg(HLA-A2.1)1Enge
(NOD.B6-Mcph1Tg(HLA-A2.1)1Enge)
immune system phenotype J:109851
increased susceptibility to autoimmune diabetes J:109851
Mcph1tm1.2Kali/Mcph1tm1.2Kali
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal T cell physiology J:156371
Mcph1tm1a(EUCOMM)Wtsi/Mcph1tm1a(EUCOMM)Wtsi
(involves: C57BL/6 * C57BL/6N)
increased B cell number J:213427
Mcpt1tm1Hrpm/Mcpt1tm1Hrpm
(involves: 129P2/OlaHsd * MF1)
abnormal mast cell morphology J:93795
decreased circulating tumor necrosis factor level J:93616
increased susceptibility to parasitic infection J:93616, J:93795
Mcpt4tm1Mabr/Mcpt4tm1Mabr
(involves: 129X1/SvJ * C57BL/6J)
abnormal mast cell physiology J:84839
Mcpt8tm1.1(HBEGF)Hkar/Mcpt8tm1.1(HBEGF)Hkar
(B6.Cg-Mcpt8tm1.1(HBEGF)Hkar)
decreased basophil cell number J:163761
immune system phenotype J:163761
increased susceptibility to parasitic infection J:163761
McrC57BL/10J/McrNC
(involves: C57BL/10J * NC)
cutaneous mastocytosis J:8804
McrNC/McrNC
(involves: C57BL/10J * NC)
cutaneous mastocytosis J:8804
Mcts1em1(IMPC)Mbp/Y
(C57BL/6N-Mcts1em1(IMPC)Mbp/Ucd)
enlarged spleen J:211773
Mdc1Gt(OST441263)Lex/Mdc1Gt(OST441263)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal class switch recombination J:137341
small spleen J:137341
small thymus J:137341
Mdficem#Nlh/Mdficem#Nlh
(C57BL/6J-Mdficem#Nlh)
abnormal lymph circulation J:326462
abnormal lymphatic vessel morphology J:326462
Mdga2Tg(Prnp-PFN1*G118V)838Kiaei/Mdga2+
(involves: C57BL/6N)
microgliosis J:241428
Mdktm1Tmu/Mdktm1Tmu
(129S2-Mdktm1Tmu)
tubular nephritis J:93637
Mdktm1Tmu/Mdktm1Tmu
(B6.129S2-Mdktm1Tmu)
abnormal macrophage chemotaxis J:102069
decreased macrophage cell number J:102069
impaired neutrophil chemotaxis J:102069
Mdm2tm1.1Ypz/Mdm2tm1.1Ypz
Tg(IghMyc)22Bri/0

(B6.Cg-Mdm2tm1.1Ypz Tg(IghMyc)22Bri)
enlarged lymph nodes J:164200
enlarged Peyer's patches J:164200
enlarged thymus J:164200
spleen hyperplasia J:164200
Mdm2tm1Bay/Mdm2tm1Mep
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal B cell differentiation J:81065
decreased double-negative T cell number J:81065
decreased double-positive T cell number J:81065
decreased granulocyte number J:81065
decreased immature B cell number J:81065
decreased leukocyte cell number J:81065
decreased lymphocyte cell number J:81065
decreased neutrophil cell number J:81065
decreased spleen weight J:81065
decreased T cell number J:81065
decreased thymocyte number J:81065
decreased thymus weight J:81065
spleen hypoplasia J:81065
thymus hypoplasia J:81065
Mdm2tm1Glo/Mdm2+
Mdm4tm1Glo/Mdm4+

(involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6)
decreased leukocyte cell number J:123661
spleen atrophy J:123661
spleen hypoplasia J:123661
thymus atrophy J:123661
thymus hypoplasia J:123661
Mdm2tm1Glo/Mdm2+
Trp53tm2Wahl/Trp53tm2Wahl

(involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6)
decreased leukocyte cell number J:174375
small thymus J:174375
spleen atrophy J:174375
Mdm2tm1Mep/Mdm2tm1.1Mep
(involves: 129S7/SvEvBrd * C57BL/6 * FVB)
decreased spleen weight J:81065
decreased thymus weight J:81065
Mdm2tm2.1Snj/Mdm2tm2.1Snj
(involves: 129S4/SvJae * C57BL/6)
decreased thymocyte apoptosis J:189297
enlarged spleen J:189297
Mdm2tm3.1Snj/Mdm2tm3.1Snj
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:189297
Mdm4m1Btlr/Mdm4m1Btlr
(C57BL/6J-Mdm4m1Btlr)
decreased CD8-positive, alpha-beta T cell number J:265262
decreased single-positive T cell number J:265262
increased CD4-positive, alpha-beta T cell number J:265262
increased single-positive T cell number J:265262
Mdm4m2Btlr/Mdm4m2Btlr
(C57BL/6J-Mdm4m2Btlr)
decreased CD8-positive, alpha-beta T cell number J:272830
increased CD4-positive, alpha-beta T cell number J:272830
Mdm4tm1.1Wahl/Mdm4tm1.1Wahl
(involves: 129S/Sv * C57BL/6)
decreased thymocyte apoptosis J:150341
increased leukocyte cell number J:150341
Me1em1(IMPC)Tcp/Me1em1(IMPC)Tcp
(C57BL/6NCrl-Me1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
MecomJbo/Mecom+
(C3N.C-MecomJbo)
abnormal neutrophil differentiation J:113445
immune system phenotype J:113445
increased susceptibility to otitis media J:113445
respiratory system inflammation J:113445
MecomJbo/Mecom+
(involves: BALB/c)
increased susceptibility to otitis media J:250208
Mecomtm1Aspe/Mecomtm1Aspe
(involves: 129S6/SvEvTac * C57BL/6)
increased leukocyte cell number J:178429
Mecomtm2.2Aspe/Mecomtm2.2Aspe
(involves: 129 * C57BL/6J * FVB/N)
abnormal immune system organ morphology J:213829
decreased B cell number J:213829
decreased leukocyte cell number J:213829
Mecp2tm1.1Bird/Y
SqleSum3-Jus/Sqle+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J)
dermatitis J:198551
Mecp2tm1.1Bird/Y
Sum2M1Jus/Sum2+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J)
dermatitis J:198551
eye inflammation J:198551
Mecp2tm1.1Bird/Y
Sum4M1Jus/Sum4+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J)
dermatitis J:198551
eye inflammation J:198551
Mecp2tm1.1Bird/Y
Sum5M1Jus/Sum5+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J)
eye inflammation J:198551
Med18tm1a(EUCOMM)Wtsi/Med18+
(C57BL/6N-Med18tm1a(EUCOMM)Wtsi/H)
decreased leukocyte cell number J:165965
Med19tm1c(EUCOMM)Wtsi/Med19tm1c(EUCOMM)Wtsi
Tg(Adipoq-icre/ERT2)1Soff/0

(involves: C57BL/6J * C57BL/6N)
white adipose tissue inflammation J:298822
Med20em1(IMPC)J/Med20+
(C57BL/6NJ-Med20em1(IMPC)J/J)
decreased leukocyte cell number J:211773
Med28tm1.1(KOMP)Vlcg/Med28+
(C57BL/6N-Med28tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
small spleen J:211773
Mef2btm2Rdf/Mef2b+
Tg(Cr2-cre)3Cgn/0

(involves: C57BL/6)
abnormal mature B cell morphology J:265465
enlarged lymph nodes J:265465
enlarged mesenteric lymph nodes J:265465
enlarged spleen J:265465
increased germinal center B cell number J:265465
Mef2ctm1Jjs/Mef2ctm1Jjs
Mir223tm1Fcam/Mir223tm1Fcam
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * C57BL/6)
abnormal neutrophil differentiation J:140009
abnormal neutrophil physiology J:140009
increased neutrophil cell number J:140009
Mefvtm1Bhk/Mefvtm1Bhk
(129S6/SvEvTac-Mefvtm1Bhk)
immune system phenotype J:192443
increased interleukin-1 beta secretion J:192443
increased interleukin-18 secretion J:192443
Mefvtm1Chae/Mefvtm1Chae
(either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6))
decreased macrophage apoptosis J:82763
increased inflammatory response J:82763
increased susceptibility to endotoxin shock J:82763
Mefvtm3.1(MEFV)Chae/Mefvtm3.1(MEFV)Chae
(B6.129S6-Mefvtm3.1(MEFV)Chae)
arthritis J:172117
dermatitis J:172117
increased inflammatory response J:172117
increased leukocyte cell number J:172117
Mefvtm4.1(MEFV)Chae/Mefvtm4.1(MEFV)Chae
(B6.129S6-Mefvtm4.1(MEFV)Chae)
arthritis J:172117
dermatitis J:172117
increased inflammatory response J:172117
increased leukocyte cell number J:172117
Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae
(B6.129S6-Mefvtm5.1(MEFV)Chae)
abnormal cytokine secretion J:172117
abnormal spleen germinal center morphology J:172117
arthritis J:172117
decreased B cell number J:172117
decreased interleukin-3 secretion J:172117
decreased lymphocyte cell number J:172117
decreased T cell number J:172117
dermatitis J:172117
enlarged lymph nodes J:172117
enlarged spleen J:172117
increased circulating interleukin-1 beta level J:172117
increased circulating interleukin-6 level J:172117
increased circulating tumor necrosis factor level J:172117
increased granulocyte number J:172117
increased inflammatory response J:172117
increased interferon-gamma secretion J:172117
increased interleukin-1 alpha secretion J:172117
increased interleukin-1 beta secretion J:172117
increased interleukin-2 secretion J:172117
increased interleukin-4 secretion J:172117
increased interleukin-5 secretion J:172117
increased interleukin-9 secretion J:172117
increased interleukin-10 secretion J:172117
increased interleukin-12 secretion J:172117
increased interleukin-12b secretion J:172117
increased interleukin-13 secretion J:172117
increased interleukin-17 secretion J:172117
increased leukocyte cell number J:172117
increased macrophage cell number J:172117
increased monocyte cell number J:172117
increased neutrophil cell number J:172117
joint inflammation J:172117
liver inflammation J:172117
skin inflammation J:172117
Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae
Nlrp3tm1Tsc/Nlrp3tm1Tsc

(involves: 129S6/SvEvTac * C57BL/6)
increased inflammatory response J:172117
increased interleukin-1 beta secretion J:172117
Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae
Pycardtm1Tno/Pycardtm1Tno

(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
decreased interleukin-1 beta secretion J:172117
immune system phenotype J:172117
Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae
Rag1tm1Mom/Rag1tm1Mom

(involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6)
abnormal cytokine secretion J:172117
increased circulating interleukin-1 beta level J:172117
increased circulating interleukin-6 level J:172117
increased circulating tumor necrosis factor level J:172117
increased inflammatory response J:172117
increased interferon-gamma secretion J:172117
increased interleukin-1 beta secretion J:172117
increased interleukin-2 secretion J:172117
increased interleukin-4 secretion J:172117
increased interleukin-5 secretion J:172117
increased interleukin-9 secretion J:172117
increased interleukin-10 secretion J:172117
increased interleukin-12 secretion J:172117
increased interleukin-13 secretion J:172117
increased interleukin-17 secretion J:172117
Megf8b2b1702.2Clo/Megf8b2b1702.2Clo
(C57BL/6J-Megf8b2b1702.2Clo)
spleen hypoplasia J:175213
thymus hypoplasia J:175213
Megf8hlb611/Megf8hlb611
(involves: C57BL/6J)
absent spleen J:146805
accessory spleen J:146805
Megf8hlb611/Megf8hlb611
(involves: C57BL/6J * C3H/HeJ)
absent spleen J:146957
accessory spleen J:146957
Mei4em1(IMPC)Mbp/Mei4em1(IMPC)Mbp
(C57BL/6NCrl-Mei4em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Meis3tm1b(EUCOMM)Hmgu/Meis3tm1b(EUCOMM)Hmgu
(C57BL/6N-Meis3tm1b(EUCOMM)Hmgu/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Men1tm1.2Zqw/Men1tm1.2Zqw
Pgrtm2(cre)Lyd/Pgr+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased uterine NK cell number J:322043
Men1tm1Ctre/Men1+
(either: (involves: 129S6/SvEvTac * FVB/N) or (involves: 129S6/SvEvTac * Black Swiss * FVB/N))
pancreas inflammation J:67128
Meox2tm1(cre)Sor/Meox2+
Procrtm2Cte/Procrtm2Cte

(involves: 129S4/SvJaeSor * 129S7/SvEvBrd * Black Swiss * C57BL/6)
decreased circulating fibrinogen level J:119529
increased circulating C-reactive protein level J:119529
Meox2tm1(cre)Sor/Meox2+
Slc40a1tm2Nca/Slc40a1tm2Nca

(involves: 129S4/SvJae * 129S6/SvEvTac)
increased spleen iron level J:129846
Meox2tm1(cre)Sor/Meox2+
Tg(CAG-lacZ,-FUS*R521G,-EGFP)682Gyu/0

(involves: 129S4/SvJaeSor * C57BL/6)
microgliosis J:216672
Meox2tm1(cre)Sor/Meox2+
Tg(CAG-lacZ,-FUS,-EGFP)629Gyu/0

(involves: 129S4/SvJaeSor * C57BL/6)
microgliosis J:216672
Mep1atm1Bond/Mep1atm1Bond
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal chemokine level J:145685
abnormal circulating interleukin-1 beta level J:145037
abnormal cytokine level J:145037, J:145685
abnormal leukocyte physiology J:145037
abnormal tumor necrosis factor level J:145037
increased circulating interleukin-1 beta level J:145685
increased circulating interleukin-6 level J:145685
increased susceptibility to induced colitis J:145685
urinary bladder inflammation J:145037
Mep1btm1Bond/Mep1btm1Bond
(B6.129-Mep1btm1Bond)
immune system phenotype J:145037
Mep1btm1Bond/Mep1btm1Bond
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased inflammatory response J:132021
Mepetm1Tbrw/Mepetm1Tbrw
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast morphology J:81218
Mertknmf12/Mertknmf12
(involves: C57BL/6J)
abnormal tumor necrosis factor level J:175587
Mertktm1Gkm/Mertktm1Gkm
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
increased circulating tumor necrosis factor level J:53423
increased susceptibility to endotoxin shock J:53423
increased tumor necrosis factor secretion J:53423
Mertktm1Gkm/Mertktm1Gkm
(NOD.129P2-Mertktm1Gkm)
abnormal mononuclear cell morphology J:147153
decreased susceptibility to autoimmune diabetes J:147153
decreased T cell number J:147153
increased T cell apoptosis J:147153
insulitis J:147153
Mertktm1Gkm/Mertktm1Gkm
(B6.129P2-Mertktm1Gkm)
decreased autoantibody level J:136377
decreased susceptibility to graft versus host disease J:136377
Mertktm1Gkm/Mertktm1Gkm
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(NOD.Cg-Mertktm1Gkm Tg(TcraBDC2.5,TcrbBDC2.5)1Doi)
decreased double-positive T cell number J:147153
increased CD8-positive, alpha-beta T cell number J:147153
increased T cell apoptosis J:147153
Mertktm1Grl/Mertktm1Grl
(involves: 129P2/OlaHsd)
enlarged spleen J:54681
Mesp1tm2(cre)Ysa/Mesp1+
Tbx1tm1Bld/Tbx1tm3Bld

(involves: 129S7/SvEvBrd * C57BL/6 * CBA)
athymia J:112457
thymus hypoplasia J:112457
Mesp1tm2(cre)Ysa/Mesp1+
Tbx1tm1Bld/Tbx1tm5Bld

(involves: 129S7/SvEvBrd * C57BL/6 * CBA)
athymia J:112457
Mettm1Gvw/Met+
(involves: 129 * C57BL/6J)
glomerulonephritis J:94722
Mettm2Gvw/Met+
(involves: 129 * C57BL/6J)
glomerulonephritis J:94722
Mettm4Gvw/Met+
(involves: 129 * C57BL/6J)
glomerulonephritis J:94722
Metrnem1(IMPC)Mbp/Metrnem1(IMPC)Mbp
(C57BL/6NCrl-Metrnem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Metrnltm1d(KOMP)Wtsi/Metrnltm1d(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
decreased IgG level J:268270
increased IgM level J:268270
increased susceptibility to endotoxin shock J:268270
kidney inflammation J:268270
liver inflammation J:268270
uterus inflammation J:268270
Mettl4em1Dfel/Mettl4em1Dfel
(involves: 129/Sv * C57BL/6N)
decreased leukocyte cell number J:278437
enlarged spleen J:278437
Mettl5em1(IMPC)Hmgu/Mettl5em1(IMPC)Hmgu
(C57BL/6N-Mettl5em1(IMPC)Hmgu/Ieg)
increased spleen weight J:211773
Mettl14em1(IMPC)Tcp/Mettl14+
(C57BL/6NCrl-Mettl14em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
small spleen J:211773
Mettl23em1(IMPC)Hmgu/Mettl23em1(IMPC)Hmgu
(C57BL/6NCrl-Mettl23em1(IMPC)Hmgu/Ieg)
enlarged spleen J:211773
increased spleen weight J:211773
Mettl25em1(IMPC)Bay/Mettl25em1(IMPC)Bay
(C57BL/6N-Mettl25em1(IMPC)Bay/BayMmucd)
increased spleen weight J:211773
Mex3btm1.1Mbld/Mex3btm1.1Mbld
Plekha5Tg(AMH-cre)1Flor/Plekha5+

(involves: C57BL/6 * SJL)
increased anti-sperm antibody level J:213588
Mex3btm1.2Mbld/Mex3btm1.2Mbld
(involves: C57BL/6 * CBA)
impaired macrophage phagocytosis J:213588
Mex3ctm1Aki/Mex3ctm1Aki
(involves: 129X1/SvJ * C57BL/6)
abnormal cytokine secretion J:208870
decreased interferon-beta secretion J:208870
decreased interleukin-6 secretion J:208870
decreased interleukin-12 secretion J:208870
Mexistm1.1Pton/Mexistm1.1Pton
(involves: C57BL/6)
increased macrophage derived foam cell number J:264834
Mfap2tm1a(KOMP)Wtsi/Mfap2tm1a(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
decreased B cell number J:236092
decreased leukocyte cell number J:236092
decreased neutrophil cell number J:236092
increased B cell number J:236092
increased macrophage cell number J:236092
increased monocyte cell number J:236092
increased myeloid dendritic cell number J:236092
increased splenocyte number J:236092
Mfap2tm1Mech/Mfap2tm1Mech
(involves: 129X1/SvJ)
decreased macrophage cell number J:203960
decreased monocyte cell number J:203960
Mfap2tm1Mech/Mfap2tm1Mech
Mfap5tm1Mech/Mfap5tm1Mech

(involves: 129X1/SvJ)
decreased monocyte cell number J:203960
decreased neutrophil cell number J:203960
immune system phenotype J:203960
Mfap4tm1b(NCOM)Mfgc/Mfap4tm1b(NCOM)Mfgc
(C57BL/6N-Mfap4tm1b(NCOM)Mfgc/Tcp)
enlarged lymph nodes J:211773
Mfap5tm1Mech/Mfap5tm1Mech
(Not Specified)
decreased neutrophil cell number J:203960
immune system phenotype J:203960
Mfge8Gt(KST227)Byg/Mfge8Gt(KST227)Byg
(B6.129P2-Mfge8Gt(KST227)Byg)
enlarged spleen J:98314
impaired macrophage phagocytosis J:98314
Mfge8Gt(KST227)Byg/Mfge8Gt(KST227)Byg
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:107106
impaired macrophage phagocytosis J:107106
mastitis J:107106
Mfge8tm1Mcu/Mfge8tm1Mcu
(involves: 129X1/SvJ * C57BL/6NCr)
enlarged spleen J:123138
Mfge8tm1Mcu/Mfge8tm1Mcu
Tg(RIP1-Tag)2Dh/?

(involves: 129X1/SvJ * C57BL/6J * C57BL/6NCr * DBA/2J)
decreased Langerhans cell number J:123138
Mfge8tm1Osa/Mfge8tm1Osa
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal spleen morphology J:90633
enlarged spleen J:90633
impaired macrophage phagocytosis J:90633
increased anti-double stranded DNA antibody level J:225063
increased spleen B cell follicle size J:90633
increased spleen weight J:90633
increased spleen white pulp amount J:90633
spleen hyperplasia J:90633
Mfge8tm1Osa/Mfge8tm1Osa
(B6.129-Mfge8tm1Osa)
immune system phenotype J:187181
Mfge8tm1Osa/Mfge8tm1Osa
Timd4tm1Osa/Timd4tm1Osa

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
impaired macrophage phagocytosis J:187181
increased anti-double stranded DNA antibody level J:187181
increased anti-nuclear antigen antibody level J:187181
Mfge8tm1Shur/Mfge8tm1Shur
(B6.129-Mfge8tm1Shur)
spermatic granuloma J:145962
Mfngem1(IMPC)Ccpcz/Mfngem1(IMPC)Ccpcz
(C57BL/6NCrl-Mfngem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
decreased NK T cell number J:211773
enlarged thymus J:211773
Mfngtm1.1Cfg/Mfngtm1.1Cfg
(involves: C57BL/6)
decreased macrophage cell number J:217719
decreased mature B cell number J:217719
decreased neutrophil cell number J:217719
increased B cell number J:217719
increased B cell proliferation J:217719
increased lymphocyte cell number J:217719
Mfngtm1Cjg/Mfngtm1Cjg
(B6.Cg-Mfngtm1Cjg)
abnormal marginal zone B cell morphology J:146621
Mfsd1em1(IMPC)Tcp/Mfsd1+
(C57BL/6N-Mfsd1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Mfsd1em1(IMPC)Tcp/Mfsd1em1(IMPC)Tcp
(C57BL/6N-Mfsd1em1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Mfsd1tm1a(KOMP)Wtsi/Mfsd1tm1a(KOMP)Wtsi
(involves: C57BL/6N)
enlarged spleen J:280713
Mfsd2atm1Dls/Mfsd2atm1Dls
(B6.Cg-Mfsd2atm1Dls)
abnormal microglial cell activation J:234197
Mfsd2btm1a(KOMP)Wtsi/Mfsd2btm1a(KOMP)Wtsi
(C57BL/6-Mfsd2btm1a(KOMP)Wtsi)
decreased B cell number J:250123
decreased leukocyte cell number J:250123
decreased T cell number J:250123
enlarged spleen J:250123
increased susceptibility to type I hypersensitivity reaction J:250123
Mfsd8tm1a(EUCOMM)Hmgu/Mfsd8tm1a(EUCOMM)Hmgu
(involves: C57BL/6N)
abnormal spleen morphology J:211608
CNS inflammation J:211608
microgliosis J:211608
Mfsd10tm1.1(KOMP)Vlcg/Mfsd10tm1.1(KOMP)Vlcg
(C57BL/6N-Mfsd10tm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Mgat2tm1.1Jxm/Mgat2tm1.1Jxm
(involves: 129S1/Sv * 129X1/SvJ * ICR)
abnormal B cell differentiation J:80661
decreased T cell number J:80661
enlarged lymph nodes J:80661
enlarged spleen J:80661
glomerulonephritis J:80661
Mgat4btm1.1Jxm/Mgat4btm1.1Jxm
(B6.129-Mgat4btm1.1Jxm)
decreased neutrophil cell number J:212313
increased leukocyte cell number J:212313
Mgat4dtm1b(KOMP)Wtsi/Mgat4dtm1b(KOMP)Wtsi
(C57BL/6N-Mgat4dtm1b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Mgat5tm1Jwd/Mgat5tm1Jwd
(involves: 129S1/Sv * 129X1/SvJ)
abnormal inflammatory response J:60960
abnormal leukocyte physiology J:94864
abnormal T cell physiology J:60960
decreased interleukin-2 secretion J:94864
decreased interleukin-4 secretion J:94864
increased interleukin-10 secretion J:94864
increased tumor necrosis factor secretion J:94864
Mgat5btm1.1Cfg/Mgat5btm1.1Cfg
(involves: 129S6/SvEvTac)
decreased pre-B cell number J:217719
enhanced humoral immune response J:217719
increased IgG2b level J:217719
Mgat5btm1Nta/Mgat5btm1Nta
(Not Specified)
brain inflammation J:199165
Mgl2tm1.1(HBEGF/EGFP)Aiwsk/Mgl2+
(involves: C57BL/6 * FVB/N)
abnormal immune system physiology J:201044
abnormal lymph node size J:201044
abnormal T-helper 2 cell morphology J:201044
decreased B cell number J:201044
decreased CD4-positive, alpha-beta T cell number J:201044
decreased CD8-positive, alpha-beta T cell number J:201044
decreased dendritic cell number J:201044
decreased interleukin-4 secretion J:201044
decreased Langerhans cell number J:201044
increased susceptibility to parasitic infection J:201044
Mgrn1em1(IMPC)Tcp/Mgrn1+
(C57BL/6NCrl-Mgrn1em1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
increased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Mgrn1em1(IMPC)Tcp/Mgrn1em1(IMPC)Tcp
(C57BL/6NCrl-Mgrn1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Mgst2em1(IMPC)Mbp/Mgst2em1(IMPC)Mbp
(C57BL/6N-Mgst2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Mical2em1(IMPC)Tcp/Mical2em1(IMPC)Tcp
(C57BL/6NCrl-Mical2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Mical3em1(IMPC)J/Mical3em1(IMPC)J
(C57BL/6NJ-Mical3em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Micu1em#Fink/Micu1em#Fink
(C57BL/6N-Micu1em#Fink)
decreased B cell number J:238984
decreased follicular B cell number J:238984
increased B cell apoptosis J:238984
Micu1em#Fink/Micu1em#Fink
Smdt1em1Fink/Smdt1+

(involves: C57BL/6J * C57BL/6N * CBA)
decreased B cell number J:238984
Micu1tm1bNarl/Micu1tm1bNarl
(C57BL/6N-Micu1tm1bNarl/Narl)
enlarged spleen J:211773
Mid1em1(IMPC)Mbp/Mid1em1(IMPC)Mbp
(C57BL/6NCrl-Mid1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Mid2tm1b(KOMP)Wtsi/Y
(C57BL/6N-Mid2tm1b(KOMP)Wtsi/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Mideasem1Shmc/Mideasem1Shmc
(C57BL/6J-Mideasem1Shmc)
immune system phenotype J:291786
Miftm1Dvd/Miftm1Dvd
(involves: 129S4/SvJae * C57BL/6)
decreased circulating tumor necrosis factor level J:52300
decreased susceptibility to bacterial infection J:52300
decreased susceptibility to endotoxin shock J:52300
increased interleukin-4 secretion J:52300
increased susceptibility to parasitic infection J:52300
Miftm1Mky/Miftm1Mky
(C.129-Miftm1Mky)
abnormal cytokine secretion J:106380
abnormal inflammatory response J:106380
decreased eosinophil cell number J:106380
MijuC3HeB/FeJ/MijuC57BL/6J
(involves: C3HeB/FeJ * C57BL/6J)
increased IgA level J:91062
Milr1tm1Shib/Milr1tm1Shib
(involves: C57BL/6N)
decreased mast cell degranulation J:161854
increased susceptibility to type I hypersensitivity reaction J:161854
Minar1em1(IMPC)Tcp/Minar1em1(IMPC)Tcp
(C57BL/6NCrl-Minar1em1(IMPC)Tcp/Tcp)
abnormal thymus morphology J:211773
Mink1em1(IMPC)Tcp/Mink1em1(IMPC)Tcp
(C57BL/6N-Mink1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Mir10bem1Rosay/Mir10bem1Rosay
(C57BL/6J-Mir10bem1Rosay)
large intestinal inflammation J:342486
Mir21atm1.1Mer/Mir21atm1.1Mer
(involves: 129S1/Sv * C57BL/6 * FVB/N)
abnormal cytokine level J:179235
abnormal cytokine secretion J:179235
abnormal interferon level J:179235
abnormal interleukin level J:179235
decreased interleukin-4 secretion J:179235
increased interferon-gamma secretion J:179235
increased interleukin-12 secretion J:179235
increased susceptibility to type I hypersensitivity reaction J:179235
Mir21atm1.1Mer/Mir21atm1.1Mer
(B6.129S1-Mir21atm1.1Mer)
increased susceptibility to type IV hypersensitivity reaction J:179235
Mir33tm1.1Koho/Mir33tm1.1Koho
(involves: C57BL/6)
abnormal macrophage physiology J:165420
Mir34atm1.1Pisc/Mir34atm1.1Pisc
Mirc21tm1.1Pisc/Mirc21tm1.1Pisc
Mirc34tm1.1Pisc/Mirc34tm1.1Pisc

(involves: 129S4/SvJae * C57BL/6 * C57BL/6J)
increased susceptibility to bacterial infection induced morbidity/mortality J:256929
nasal inflammation J:256929
Mir34atm1.2Arte/Mir34atm1.2Arte
(involves: C57BL/6N)
abnormal immune system cell morphology J:221990
increased B cell number J:221990
Mir100em1Nju/Mir100em1Nju
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: C57BL/6 * DBA)
liver inflammation J:281439
Mir122tm1.1Apts/Mir122tm1.1Apts
(involves: 129 * C57BL/6)
increased circulating interleukin-6 level J:190066
increased macrophage cell number J:190066
increased monocyte cell number J:190066
liver inflammation J:190066
Mir122tm1.1Kgh/Mir122tm1.1Kgh
(involves: 129S1/Sv * 129X1/SvJ)
increased circulating interleukin-6 level J:190067
liver inflammation J:190067
Mir122tm1.2Kgh/Mir122tm1.2Kgh
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA)
increased circulating interleukin-6 level J:190067
increased interleukin-6 secretion J:190067
increased monocyte cell number J:190067
increased neutrophil cell number J:190067
increased tumor necrosis factor secretion J:190067
liver inflammation J:190067
Mir125atm1Smoc/Mir125atm1Smoc
(involves: C57BL/6)
abnormal regulatory T cell physiology J:224880
decreased regulatory T cell number J:224880
immune system phenotype J:224880
increased interferon-gamma secretion J:224880
increased interleukin-17 secretion J:224880
increased susceptibility to experimental autoimmune encephalomyelitis J:224880
Mir139em1Jwli/Mir139em1Jwli
(C57BL/6J-Mir139em1Jwli)
abnormal cytokine level J:248779
increased susceptibility to colitis induced morbidity/mortality J:280467, J:248779
increased susceptibility to induced colitis J:248779
Mir140tm1.1Asah/Mir140tm1.1Asah
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
increased susceptibility to induced arthritis J:160358
osteoarthritis J:160358
Mir142tm1.1Sbel/Mir142tm1.1Sbel
(involves: C57BL/6N)
decreased eosinophil cell number J:227228
decreased leukocyte cell number J:227228
decreased lymphocyte cell number J:227228
decreased monocyte cell number J:227228
Mir142tm1Teyo/Mir142tm1Teyo
(involves: C57BL/6)
decreased mast cell degranulation J:211850
Mir142hgGt(IST11580H2)Tigm/Mir142hgGt(IST11580H2)Tigm
(involves: C57BL/6N)
abnormal dendritic cell differentiation J:207516
abnormal dendritic cell morphology J:207516
decreased dendritic cell number J:207516
enlarged spleen J:207516
immune system phenotype J:207516
increased dendritic cell number J:207516
increased neutrophil cell number J:207516
Mir144/Mir451atm1.1Mjwe/Mir144/Mir451atm1.1Mjwe
(Not Specified)
increased spleen weight J:163250
spleen hyperplasia J:163250
Mir144/Mir451atm1.1Mjwe/Mir144/Mir451atm1.1Mjwe
(Not Specified)
increased spleen weight J:163250
spleen hyperplasia J:163250
Mir144/Mir451atm1.2Doca/Mir144/Mir451atm1.2Doca
(involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ)
enlarged spleen J:163418
Mir144/Mir451atm1.2Doca/Mir144/Mir451atm1.2Doca
(involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ)
enlarged spleen J:163418
Mir146tm1.1Bal/Mir146tm1.1Bal
(involves: C57BL/6)
abnormal lymphopoiesis J:167922
abnormal regulatory T cell physiology J:167922
decreased interferon-gamma secretion J:167922
decreased leukocyte cell number J:173230
decreased lymphocyte cell number J:173230
decreased monocyte cell number J:173230
enlarged spleen J:173230
increased regulatory T cell number J:167922
increased spleen weight J:173230
myeloid hyperplasia J:167922, J:173230
Mir146tm1.1Bal/Mir146tm1.1Bal
(involves: C57BL/6 * FVB/N)
abnormal immune system physiology J:173671
abnormal immune tolerance J:173671
abnormal macrophage physiology J:173671
abnormal T cell activation J:173671
increased circulating interleukin-1 beta level J:173671
increased circulating interleukin-6 level J:173671
increased circulating interleukin-10 level J:173671
increased circulating tumor necrosis factor level J:173671
increased interleukin-1 beta secretion J:173671
increased interleukin-6 secretion J:173671
increased macrophage nitric oxide production J:173671
increased susceptibility to bacterial infection induced morbidity/mortality J:173671
increased susceptibility to endotoxin shock J:173671
increased tumor necrosis factor secretion J:173671
myeloid hyperplasia J:173671
Mir146tm1.1Bal/Mir146tm1.1Bal
Tifabtm1.1Dsta/Tifabtm1.1Dsta

(involves: 129 * C57BL/6 * C57BL/6J)
decreased lymphocyte cell number J:229024
decreased neutrophil cell number J:229024
Mir146tm1.1Lfl/Mir146tm1.1Lfl
Ighg1tm1(cre)Cgn/Ighg1+

(involves: 129P2/OlaHsd * C57BL/6)
increased germinal center B cell number J:266124
increased T follicular helper cell number J:266124
Mir146tm1.1Lfl/Mir146tm1.1Lfl
Mir146btm1.1Lfl/Mir146btm1.1Lfl
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
increased germinal center B cell number J:266124
increased IgG level J:266124
increased T follicular helper cell number J:266124
Mir146tm1.1Lfl/Mir146tm1.1Lfl
Tg(CD2-icre)4Kio/0

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
increased germinal center B cell number J:266124
increased T follicular helper cell number J:266124
Mir146tm1.1Lfl/Mir146tm1.1Lfl
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
immune system phenotype J:266124
Mir146tm1.1Lfl/Mir146tm1.1Lfl
Tg(Cr2-cre)3Cgn/0

(involves: C57BL/6)
increased anti-double stranded DNA antibody level J:266124
increased germinal center B cell number J:266124
increased IgG1 level J:266124
increased IgG level J:266124
increased plasma cell number J:266124
increased T follicular helper cell number J:266124
Mir146tm2.1Bal/Mir146tm2.1Bal
(involves: 129S1/Sv * C57BL/6 * FVB/N)
abnormal immune system physiology J:173671
abnormal immune tolerance J:173671
abnormal macrophage physiology J:173671
abnormal spleen B cell follicle morphology J:173671
abnormal T cell activation J:173671
decreased lymphocyte cell number J:173671
decreased monocyte cell number J:173671
enlarged lymph nodes J:173671
enlarged spleen J:173671
immune system phenotype J:173671
increased acute inflammation J:173671
increased anti-double stranded DNA antibody level J:173671
increased circulating interleukin-1 beta level J:173671
increased circulating interleukin-6 level J:173671
increased circulating interleukin-10 level J:173671
increased circulating tumor necrosis factor level J:173671
increased interleukin-1 beta secretion J:173671
increased interleukin-6 secretion J:173671
increased macrophage nitric oxide production J:173671
increased spleen germinal center number J:173671
increased spleen germinal center size J:173671
increased spleen weight J:173671
increased susceptibility to bacterial infection induced morbidity/mortality J:173671
increased susceptibility to endotoxin shock J:173671
increased tumor necrosis factor secretion J:173671
myeloid hyperplasia J:173671
Mir146btm1.1Lfl/Mir146btm1.1Lfl
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
immune system phenotype J:266124
Mir147tm1.2Xyn/Mir147tm1.2Xyn
(involves: C57BL/6)
immune system phenotype J:332925
Mir148atm2942.1Arte/Mir148atm2942.1Arte
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal plasmablast number J:307366
decreased IgA level J:307366
decreased IgG level J:307366
decreased IgM level J:307366
decreased plasma cell number J:307366
impaired humoral immune response J:307366
increased memory B cell number J:307366
Mir148atm2942.1Arte/Mir148atm2942.1Arte
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NTac)
abnormal B cell physiology J:307366
abnormal plasmablast number J:307366
decreased plasma cell number J:307366
impaired humoral immune response J:307366
increased plasma cell number J:307366
Mir148atm2942.2Arte/Mir148atm2942.2Arte
(involves: C57BL/6 * FVB/N)
abnormal B cell physiology J:307366
decreased plasma cell number J:307366
Mir149em1Ydw/Mir149em1Ydw
(C57BL/6J-Mir149em1Ydw)
increased susceptibility to endotoxin shock J:294318
Mir150tm1Rsky/Mir150tm1Rsky
(involves: C57BL/6)
decreased B-2 B cell number J:127234
increased B-1 B cell number J:127234
increased IgA level J:127234
increased IgG1 level J:127234
increased IgG2b level J:127234
increased IgM level J:127234
Mir155tm1.1Brd/Mir155tm1.1Brd
(B6.Cg-Mir155tm1.1Brd Tyrc-Brd)
abnormal CD4-positive, alpha beta T cell morphology J:121095
abnormal CD4-positive, alpha-beta T cell physiology J:121095
abnormal dendritic cell physiology J:121095
abnormal T-helper 1 cell morphology J:121095
decreased IgG1 level J:121095
immune system phenotype J:121095
increased susceptibility to bacterial infection J:121095
increased T-helper 2 cell number J:121095
Mir155tm1.1Brd/Mir155tm1.1Brd
(B6.129S7-Mir155tm1.1Brd)
decreased regulatory T cell number J:146268
Mir155tm1.1Rsky/Mir155tm1.1Rsky
(involves: 129 * C57BL/6)
abnormal B cell physiology J:121084
abnormal cytokine secretion J:121084
abnormal germinal center B cell physiology J:121084
abnormal humoral immune response J:121084
abnormal T cell physiology J:121084
decreased germinal center B cell number J:121084
Mir155tm1.1Rsky/Mir155tm1.1Rsky
(B6.Cg-Mir155tm1Rsky/J)
abnormal T cell physiology J:226678
abnormal T-helper 17 cell differentiation J:226678
decreased effector memory T-helper cell number J:226678
decreased interleukin-6 secretion J:226678
decreased regulatory T cell number J:226678
decreased susceptibility to experimental autoimmune encephalomyelitis J:226678
decreased T-helper 17 cell number J:226678
Mir155tm1Brd/Mir155tm1Brd
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal B cell physiology J:121095
abnormal class switch recombination J:121095
abnormal cytokine secretion J:121095
decreased IgM level J:121095
immune system phenotype J:121095
intestinal inflammation J:121095
lung inflammation J:121095
Mir155tm1Rsky/Mir155tm1Rsky
(involves: 129/Sv * C57BL/6)
abnormal cytokine secretion J:121084
abnormal gut-associated lymphoid tissue morphology J:121084
abnormal humoral immune response J:121084
abnormal immune system morphology J:121084
abnormal immune system physiology J:121084
abnormal Peyer's patch germinal center morphology J:121084
decreased interferon-gamma secretion J:121084
decreased interleukin-4 secretion J:121084
decreased spleen germinal center number J:121084
decreased spleen germinal center size J:121084
decreased tumor necrosis factor secretion J:121084
increased interleukin-10 secretion J:121084
Mir155tm1Rsky/Mir155tm1Rsky
(involves: 129 * C57BL/6)
abnormal class switch recombination J:136224
Mir181dtm1.1Oers/Mir181dtm1.1Oers
(involves: C57BL/6)
immune system phenotype J:212571
increased T cell number J:212571
Mir205hgtm1.1Oers/Mir205hgtm1.1Oers
(B6(Cg)-Mir205hgtm1.1Oers)
small thymus J:278363
Mir210tm1.1Wtsi/Mir210tm1.1Wtsi
(involves: C57BL/6J * C57BL/6N)
decreased germinal center B cell number J:205868
immune system phenotype J:205868
increased anti-chromatin antibody level J:205868
increased anti-double stranded DNA antibody level J:205868
increased anti-nuclear antigen antibody level J:205868
Mir216aem1Uf/Mir216aem1Uf
(C57BL/6-Mir216aem1Uf)
increased susceptibility to induced pancreatitis J:278847
Mir216aem2Uf/Mir216aem2Uf
(C57BL/6-Mir216aem2Uf)
increased susceptibility to induced pancreatitis J:278847
Mir216bem1Uf/Mir216bem1Uf
(C57BL/6-Mir216bem1Uf)
increased susceptibility to induced pancreatitis J:278847
Mir217em1Uf/Mir217em1Uf
(C57BL/6-Mir217em1Uf)
increased susceptibility to induced pancreatitis J:278847
Mir217em2Uf/Mir217em2Uf
(C57BL/6-Mir217em2Uf)
increased susceptibility to induced pancreatitis J:278847
Mir223tm1Fcam/Mir223tm1Fcam
(involves: 129S4/SvJae * C57BL/6)
abnormal granulocyte physiology J:140009
abnormal neutrophil differentiation J:140009
abnormal neutrophil physiology J:140009
increased acute inflammation J:140009
increased granulocyte number J:140009
increased neutrophil cell number J:140009
lung inflammation J:140009
Mir301tm1Yoli/Mir301tm1Yoli
(involves: C57BL/6J)
abnormal response to transplant J:237900
Mir338em1Zchn/Mir338em1Zchn
(C57BL/6-Mir338em1Zchn)
decreased osteoclast cell number J:285968
Mir378bem#Yoo/Mir378bem#Yoo
(C57BL/6J-Mir378bem#Yoo)
abnormal chemokine secretion J:307588
abnormal susceptibility to bacterial infection J:307588
decreased interferon-gamma secretion J:307588
decreased interleukin-12 secretion J:307588
decreased tumor necrosis factor secretion J:307588
Mir425em1Nju/Mir425+
(involves: C57BL/6)
increased tumor necrosis factor secretion J:280159
Mir451atm1.2Doca/Mir451atm1.2Doca
(involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ)
enlarged spleen J:163418
Mir451atm1Eno/Mir451atm1Eno
(involves: C57BL/6)
enlarged spleen J:163251
Mir511em1Clib/Mir511em1Clib
(C57BL/6J-Mir511em1Clib)
abnormal macrophage physiology J:345580
decreased susceptibility to induced colitis J:345580
Mirc1tm1.1Aven/Mirc1tm1.1Aven
(involves: 129S4/SvJae * C57BL/6 * SJL/J)
decreased alpha-beta T cell number J:223213
decreased B cell number J:223213
decreased pre-B cell number J:223213
decreased pro-B cell number J:223213
increased B cell apoptosis J:223213
small spleen J:223213
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
(involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL)
abnormal B cell differentiation J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
Mirc1tm1.3Tyj/Mirc1tm1.3Tyj
(involves: 129S4/SvJae * C57BL/6 * FVB/N)
abnormal B cell differentiation J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
Mirc1tm1Tyj/Mirc1tm1Tyj
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA * SJL)
abnormal immunoglobulin heavy chain V(D)J recombination J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
Mirc1tm2.1Aven/Mirc1tm2.1Aven
(involves: 129S4/SvJae * C57BL/6 * SJL/J)
decreased B cell number J:223213
Mirc1tm2.1Aven/Mirc1tm2.1Aven
Tg(IghMyc)22Bri/?

(involves: 129S4/SvJae * C57BL/6 * SJL/J)
abnormal pre-B cell morphology J:223213
increased B cell apoptosis J:223213
Mirc1tm3.1Aven/Mirc1tm3.1Aven
(involves: 129S4/SvJae * C57BL/6 * SJL/J)
decreased alpha-beta T cell number J:223213
decreased B cell number J:223213
decreased pre-B cell number J:223213
decreased pro-B cell number J:223213
increased B cell apoptosis J:223213
small spleen J:223213
Mirc11tm1Rdhl/Mirc11tm1Rdhl
(B6.129-Mirc11tm1Rdhl)
abnormal B cell differentiation J:243248
immune system phenotype J:243248
impaired myelopoiesis J:243248
increased B cell number J:243248
increased follicular B cell number J:243248
increased immature B cell number J:243248
increased mature B cell number J:243248
increased plasma cell number J:243248
increased pre-pro B cell number J:243248
increased pro-B cell number J:243248
increased transitional stage T1 B cell number J:243248
Mirc13tm1.1Mtm/Mirc13tm1.1Mtm
(Not Specified)
abnormal macrophage activation involved in immune response J:256444
Mirc14tm1.1Ankr/Mirc14tm1.1Ankr
(involves: C57BL/6)
abnormal alpha-beta intraepithelial T cell morphology J:196134
abnormal NK T cell morphology J:196134
abnormal T cell differentiation J:196134
decreased double-positive T cell number J:196134
decreased interferon-gamma secretion J:196134
decreased interleukin-4 secretion J:196134
decreased interleukin-13 secretion J:196134
decreased NK T cell number J:196134
immune system phenotype J:196134
increased CD4-positive, alpha-beta T cell number J:196134
Mirc14tm1.1Czc/Mirc14tm1.1Czc
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+

(either: (involves: 129P2/OlaHsd * 129S4/SvJae * 129S4/SvJaeSor) or (involves: 129P2/OlaHsd * 129S4/SvJae * 129S4/SvJaeSor * C57BL/6))
decreased double-positive T cell number J:188125
thymus hypoplasia J:188125
Mirc14tm1.1Flv/Mirc14tm1.1Flv
Ptentm1Hwu/Ptentm1Hwu
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJae * C57BL/6 * C57BL/6N * DBA/2 * SJL)
immune system phenotype J:203157
Mirc14tm1.1Flv/Mirc14tm1.1Flv
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * C57BL/6N * DBA/2 * SJL)
decreased NK T cell number J:203157
Mirc14tm1.2Czc/Mirc14tm1.2Czc
(either: (involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor) or (involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6))
decreased B cell number J:188125
decreased DN3 thymocyte number J:188125
decreased double-positive T cell number J:188125
decreased germinal center B cell number J:188125
decreased thymocyte number J:188125
increased CD4-positive, alpha-beta T cell number J:188125
increased marginal zone B cell number J:188125
Mirc14tm1.2Flv/Mirc14tm1.2Flv
(involves: C57BL/6 * C57BL/6N * FVB/N * SJL)
abnormal T cell differentiation J:203157
abnormal T cell physiology J:203157
abnormal T cell receptor V(D)J recombination J:203157
decreased B cell number J:203157
decreased CD4-positive, alpha-beta T cell number J:203157
decreased CD8-positive, alpha-beta T cell number J:203157
decreased DN1 thymic pro-T cell number J:203157
decreased double-positive T cell number J:203157
decreased NK T cell number J:203157
decreased T cell proliferation J:203157
decreased thymocyte apoptosis J:203157
decreased thymocyte number J:203157
Mirc14tm1.2Flv/Mirc14tm1.2Flv
Mirc15tm1.2Flv/Mirc15tm1.2Flv

(involves: C57BL/6 * C57BL/6N * FVB/N * SJL)
decreased B cell number J:203157
decreased immature B cell number J:203157
decreased pre-B cell number J:203157
increased pro-B cell number J:203157
Mirc14tm1.2Flv/Mirc14tm1.2Flv
Tg(Cd4-TcraDN32D3)1Aben/0

(involves: C57BL/6 * C57BL/6N * FVB/N * SJL)
abnormal NK T cell physiology J:203157
decreased NK T cell number J:203157
Mirc14tm1.2Flv/Mirc14tm1.2Flv
Tg(LCKprBCL2L1)12Sjk/0

(involves: C57BL/6 * C57BL/6N * FVB/N * SJL)
decreased NK T cell number J:203157
Mirc15tm1.2Czc/Mirc15tm1.2Czc
(either: (involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor) or (involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6))
immune system phenotype J:188125
Mirc16tm1.2Czc/Mirc16tm1.2Czc
(either: (involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor) or (involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6))
immune system phenotype J:188125
increased CD8-positive, alpha-beta T cell number J:188125
Mirc19tm1.2Arte/Mirc19tm1.2Arte
(involves: C57BL/6N)
immune system phenotype J:200865
Mirc27em1Hhzg/Mirc27em1Hhzg
Tg(Vav1-cre)#Cgp/0

(involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj)
immune system phenotype J:320883
Mirc29tm1.1Cwh/Mirc29tm1.1Cwh
(involves: 129X1/SvJ)
immune system phenotype J:189763
Mirc30em1Hhzg/Mirc30em1Hhzg
Tg(Vav1-cre)#Cgp/0

(involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj)
abnormal NK cell morphology J:320883
increased B cell number J:320883
increased pre-B cell number J:320883
increased pro-B cell number J:320883
increased spleen weight J:320883
Mirc30tm1.2Rdf/Mirc30tm1.2Rdf
(involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
abnormal B cell proliferation J:156946
increased B cell number J:156946
increased B-1a cell number J:156946
increased spleen white pulp amount J:156946
Mirc32tm1.1Jtm/Mirc32tm1.1Jtm
Tg(Myh11-cre,-EGFP)2Mik/?

(B6.Cg-Mirc32tm1.1Jtm Tg(Myh11-cre,-EGFP)2Mik)
increased susceptibility to induced colitis J:214382
Mirc32tm1.1Jtm/Mirc32tm1.1Jtm
Twist2tm1(cre)Dor/Twist2+

(B6.129(Cg)-Twist2tm1.1(cre)Dor Mirc32tm1.1Jtm)
increased susceptibility to induced colitis J:214382
Mirc32tm1.2Jtm/Mirc32tm1.2Jtm
(B6.129(Cg)-Mirc32tm1.2Jtm)
increased susceptibility to induced colitis J:214382
Mirc33tm1.1Cwh/Mirc33tm1.1Cwh
(involves: 129X1/SvJ)
abnormal T cell morphology J:189763
decreased susceptibility to experimental autoimmune encephalomyelitis J:189763
increased interferon-gamma secretion J:189763
increased interleukin-17 secretion J:189763
increased T-helper 1 cell number J:189763
lymph node hypoplasia J:189763
lymphoid hypoplasia J:189763
spleen hypoplasia J:189763
thymus hypoplasia J:189763
Mirc33tm1Bdes/Mirc33tm1Bdes
(Not Specified)
abnormal thymus involution J:180783
Mirc40tm1Jzb/Mirc40tm1Jzb
(Not Specified)
increased microglial cell activation J:244554
Mispem1Nsas/Mispem1Nsas
(FVB/NJcl-Mispem1Nsas)
abnormal interleukin level J:333842
increased susceptibility to induced colitis J:333842
Mitfmi-di/Mitfmi-di
((PT x C3H/HeH)F1)
abnormal spleen germinal center morphology J:8196
abnormal spleen morphology J:8196
abnormal spleen red pulp morphology J:8196
abnormal spleen white pulp morphology J:8196
Mitfmi-ew/Mitfmi-ew
Tfe3tm1Est/Tfe3tm1Est

(either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW))
abnormal osteoclast morphology J:89821
MitfMi-Or/MitfMi-Or
(involves: 101/Rl * C3H/Rl)
abnormal osteoclast morphology J:30149
abnormal osteoclast physiology J:30149
decreased osteoclast cell number J:30149
increased osteoclast cell number J:30149
Mitfmi-tg/Mitfmi-tg
(B6.Cg-Mitfmi-tg)
abnormal mast cell physiology J:53161
Mitfmi-vga9/Mitfmi-vga9
Tfe3tm1Est/Tfe3tm1Est

(either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA))
abnormal osteoclast morphology J:89821
Mitfmi-vit/Mitfmi-vit
(C57BL/6J-Mitfmi-vit)
abnormal Langerhans cell physiology J:102101
MitfMi/MitfMi
(Not Specified)
abnormal osteoclast morphology J:5046
decreased mast cell number J:6889
increased osteoclast cell number J:5046
MitfMi/MitfMi
(B6.Cg-MitfMi)
abnormal mast cell physiology J:53161
MitfMi/MitfMi
(involves: C57BL/6J)
abnormal osteoclast morphology J:89821
MitfMi/MitfMi
Tfe3tm1Est/Tfe3tm1Est

(either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J))
abnormal osteoclast morphology J:89821
MitfTg(Tff3-Tmem207)2Tamo/Mitf+
(involves: C57BL/6)
kidney inflammation J:244533
Mki67em1Dfis/Mki67em1Dfis
(involves: C57BL/6J)
immune system phenotype J:304800
Mkrn2tm1b(KOMP)Wtsi/Mkrn2tm1b(KOMP)Wtsi
(C57BL/6N-Mkrn2tm1b(KOMP)Wtsi/Wtsi)
decreased dendritic epidermal T cell number J:211773
Mks1hlb614/Mks1hlb614
(involves: C3H * C57BL/6)
absent spleen J:167534
accessory spleen J:167534
Mlf1tm1Swm/Mlf1tm1Swm
(involves: 129 * C57BL/6)
decreased splenocyte apoptosis J:266833
increased B cell number J:266833
Mlh1m1Btlr/Mlh1m1Btlr
(C57BL/6J-Mlh1m1Btlr)
abnormal humoral immune response J:265206
increased IgM level J:265206
Mlh1m2Btlr/Mlh1m2Btlr
(C57BL/6J-Mlh1m2Btlr)
abnormal humoral immune response J:265207
decreased IgE level J:265207
increased IgM level J:265207
Mlh1m3Btlr/Mlh1m3Btlr
(C57BL/6J-Mlh1m3Btlr)
abnormal humoral immune response J:265208
decreased IgE level J:265208
increased IgM level J:265208
Mlh1tm1b(EUCOMM)Hmgu/Mlh1tm1b(EUCOMM)Hmgu
(C57BL/6N-Mlh1tm1b(EUCOMM)Hmgu/H)
increased spleen weight J:211773
Mlklem1Jhan/Mlklem1Jhan
(involves: C57BL/6)
abnormal macrophage physiology J:204622
immune system phenotype J:204622
Mlklm1Btlr/Mlkl+
(C57BL/6J-Mlklm1Btlr)
decreased inflammatory response J:225934
Mlklm1Btlr/Mlklm1Btlr
(C57BL/6J-Mlklm1Btlr)
decreased inflammatory response J:225934
Mlklm2Btlr/Mlkl+
(C57BL/6J-Mlklm2Btlr)
decreased inflammatory response J:234252
Mlklm2Btlr/Mlklm2Btlr
(C57BL/6J-Mlklm2Btlr)
decreased inflammatory response J:234252
Mlklm3Btlr/Mlkl+
(C57BL/6J-Mlklm3Btlr)
decreased inflammatory response J:234251
Mlklm3Btlr/Mlklm3Btlr
(C57BL/6J-Mlklm3Btlr)
decreased inflammatory response J:234251
Mlkltm1.1Wsa/Mlkltm1.1Wsa
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0

(involves: C57BL/6 * C57BL/6N * DBA/2)
dermatitis J:312394
Mllt6em1(IMPC)Tcp/Mllt6em1(IMPC)Tcp
(C57BL/6NCrl-Mllt6em1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Mllt10em1(IMPC)Mbp/Mllt10+
(C57BL/6N-Mllt10em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Mlphln-Btlr/Mlphln-Btlr
(C57BL/6J-Mlphln-Btlr)
immune system phenotype J:133625
MlrrqDBA/2/MlrrqDBA/2
(C.D2-Mtv7DBA/2)
decreased susceptibility to parasitic infection J:41574
Mmabem1(IMPC)Hmgu/Mmab+
(C57BL/6NCrl-Mmabem1(IMPC)Hmgu/Ieg)
abnormal spleen morphology J:211773
Mmachctm1.1(NCOM)Mfgc/Mmachc+
(C57BL/6N-Mmachctm1.1(NCOM)Mfgc/Tcp)
enlarged lymph nodes J:211773
Mmdtm1Beij/Mmdtm1Beij
(Not Specified)
abnormal macrophage differentiation J:304637
decreased susceptibility to induced arthritis J:304637
increased macrophage apoptosis J:304637
small inguinal lymph nodes J:304637
Mmetm1Cge/Mmetm1Cge
(B6.129S4-Mmetm1Cge)
dermatitis J:66854
increased susceptibility to type I hypersensitivity reaction J:66854
Mmgt2tm1b(EUCOMM)Wtsi/Mmgt2tm1b(EUCOMM)Wtsi
(C57BL/6N-Mmgt2tm1b(EUCOMM)Wtsi/Bay)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
Mmp1atm1Otin/Mmp1atm1Otin
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal interleukin secretion J:198586
decreased inflammatory response J:198586
increased interferon-gamma secretion J:198586
increased interleukin-1 alpha secretion J:198586
increased interleukin-2 secretion J:198586
increased interleukin-17 secretion J:198586
Mmp2em1(IMPC)Mbp/Mmp2em1(IMPC)Mbp
(C57BL/6N-Mmp2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Mmp2tm1Ito/Mmp2tm1Ito
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal inflammatory response J:46091
brain inflammation J:94099
decreased inflammatory response J:46091
increased susceptibility to experimental autoimmune encephalomyelitis J:94099
Mmp2tm1Ito/Mmp2tm1Ito
(involves: 129P2/OlaHsd)
arthritis J:121780
decreased osteoclast cell number J:121780
Mmp2tm1Ito/Mmp2tm1Ito
Timp1tm1Pds/Timp1tm1Pds

(either: (involves: 129S4/SvJae) or (involves: C57BL/6))
decreased susceptibility to bacterial infection J:94836
Mmp2tm1Ito/Mmp2tm1Ito
Timp3tm1Osya/Timp3tm1Osya

(involves: 129P2/OlaHsd * C57BL/6)
aortitis J:193744
Mmp3tm1Mrl/Mmp3tm1Mrl
(either: (129S7/SvEvBrd X B10.RIII)N2 or ((involves: 129S7/SvEvBrd * C57BL/6) X B10.RIII)N2)
arthritis J:46038
joint inflammation J:46038
osteoarthritis J:46038
Mmp3tm1Mrl/Mmp3tm1Mrl
(either: 129S7/SvEvBrd or (involves: 129S7/SvEvBrd * C57BL/6))
abnormal CD4-positive, alpha-beta T cell physiology J:93706
increased susceptibility to bacterial infection J:93706
Mmp3tm1Mrl/Mmp3tm1Mrl
(involves: 129S7/SvEvBrd * C57BL/10ScSn * RIII)
abnormal lymphocyte physiology J:55723
decreased susceptibility to type IV hypersensitivity reaction J:55723
Mmp3tm1Mrl/Mmp3tm1Mrl
(involves: 129S7/SvEvBrd)
immune system phenotype J:124841
Mmp3tm1Mrl/Mmp3tm1Mrl
Timp1tm1Pds/Timp1tm1Pds

(involves: C57BL/6)
decreased susceptibility to bacterial infection J:94836
Mmp7tm1Lmm/Mmp7tm1Lmm
(involves: 129S1/Sv * 129X1/SvJ)
decreased susceptibility to bacterial infection J:153651
immune system phenotype J:55723
Mmp7tm1Lmm/Mmp7tm1Lmm
(B6.129-Mmp7tm1Lmm)
increased interleukin-1 beta secretion J:149388
increased susceptibility to induced colitis J:149388
Mmp7tm1Lmm/Mmp7tm1Lmm
(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ)
abnormal macrophage physiology J:124841
decreased tumor necrosis factor secretion J:124841
impaired macrophage chemotaxis J:124841
Mmp7tm1Lmm/Mmp7tm1Lmm
Timp1tm1Pds/Timp1tm1Pds

(involves: 129S4/SvJae)
decreased susceptibility to bacterial infection J:94836
Mmp8tm1Otin/Mmp8tm1Otin
(involves: 129X1/SvJ * C57BL/6J)
abnormal inflammatory response J:86393
chronic inflammation J:86393
increased susceptibility to bacterial infection J:97118
Mmp8tm1Otin/Mmp8tm1Otin
(involves: 129X1/SvJ * C57BL/6)
immune system phenotype J:113463
Mmp8tm1Otin/Mmp8tm1Otin
(involves: 129X1/SvJ)
immune system phenotype J:148442
Mmp8tm1Otin/Mmp8tm1Otin
Mmp9tm1Tvu/Mmp9tm1Tvu

(involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6)
immune system phenotype J:113463
Mmp9tm1Arnd/Mmp9tm1Arnd
(involves: 129P2/OlaHsd)
decreased susceptibility to experimental autoimmune encephalomyelitis J:58833
Mmp9tm1Tvu/Mmp9tm1Tvu
(involves: 129S6/SvEvTac)
abnormal chemokine level J:84293
abnormal dendritic cell physiology J:84293
abnormal Langerhans cell physiology J:76157
decreased dendritic cell number J:84293
decreased IgE level J:84293
decreased inflammatory response J:84293
increased circulating interferon-beta level J:148442
increased circulating interferon-gamma level J:148442
increased susceptibility to Picornaviridae infection J:148442
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:148442
myocarditis J:148442
Mmp9tm1Tvu/Mmp9tm1Tvu
(FVB.129S6-Mmp9tm1Tvu)
abnormal neutrophil physiology J:104644
decreased susceptibility to induced colitis J:104644
immune system phenotype J:104644
Mmp9tm1Tvu/Mmp9tm1Tvu
(129S6/SvEvTac-Mmp9tm1Tvu)
immune system phenotype J:113463
Mmp9tm1Tvu/Mmp9tm1Tvu
(involves: 129/Sv * 129S6/SvEvTac)
decreased circulating interleukin-10 level J:55723
increased susceptibility to type IV hypersensitivity reaction J:55723
Mmp9tm1Tvu/Mmp9tm1Tvu
(involves: 129S6/SvEvTac * CD-1)
impaired myelopoiesis J:149957
Mmp9tm1Tvu/Mmp9tm1Tvu
(involves: 129S6/SvEvTac * C57BL/6)
abnormal chemokine level J:88065
abnormal cytokine secretion J:88065
abnormal leukocyte morphology J:88065
abnormal response to infection J:126519
decreased interferon-gamma secretion J:88065
increased eosinophil cell number J:88065
increased IgE level J:88065
increased interferon-gamma secretion J:88065
increased interleukin-4 secretion J:88065
increased interleukin-5 secretion J:88065
increased interleukin-13 secretion J:88065
increased lymphocyte cell number J:88065
increased macrophage cell number J:88065
increased monocyte cell number J:88065
increased T cell proliferation J:88065
increased T-helper 2 cell number J:88065
lung inflammation J:88065
Mmp9tm1Tvu/Mmp9tm1Tvu
(FVB.Cg-Mmp9tm1Tvu/J)
decreased susceptibility to Flaviviridae infection J:153406
decreased susceptibility to Flaviviridae infection induced morbidity/mortality J:153406
Mmp9tm1Tvu/Mmp9tm1Tvu
(C3N.129S6-Mmp9tm1Tvu)
decreased susceptibility to bacterial infection J:150311
decreased susceptibility to induced arthritis J:150311
joint inflammation J:150311
Mmp9tm1Tvu/Mmp9tm1Tvu
Tg(SOD1*G93A)1Gur/0

(involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL)
decreased tumor necrosis factor secretion J:141587
Mmp9tm1Tvu/Mmp9tm1Tvu
Timp1tm1Pds/Timp1tm1Pds

(involves: 129S4/SvJae * 129S6/SvEvTac)
immune system phenotype J:94836
Mmp10tm1Jkmg/Mmp10tm1Jkmg
(B6.129X1-Mmp10tm1Jkmg)
increased susceptibility to bacterial infection J:153651
lung inflammation J:153651
Mmp11tm1b(EUCOMM)Hmgu/Mmp11tm1b(EUCOMM)Hmgu
(C57BL/6N-Mmp11tm1b(EUCOMM)Hmgu/Ics)
increased monocyte cell number J:211773
Mmp12tm1Sds/Mmp12tm1Sds
(involves: 129X1/SvJ)
abnormal macrophage physiology J:32902
Mmp12tm1Sds/Mmp12tm1Sds
Timp1tm1Pds/Timp1tm1Pds

(either: (involves: 129S4/SvJae) or (involves: C57BL/6))
decreased susceptibility to bacterial infection J:94836
Mmp14tm1Hbh/Mmp14tm1Hbh
(involves: 129P2/OlaHsd * Black Swiss)
abnormal osteoclast physiology J:57969, J:86538
arthritis J:57969
Mmp14tm1Ktry/Mmp14tm1Ktry
(involves: 129X1/SvJ)
abnormal dendritic cell physiology J:138782
Mmp15tm1b(KOMP)Wtsi/Mmp15tm1b(KOMP)Wtsi
(C57BL/6N-Mmp15tm1b(KOMP)Wtsi/Bay)
absent lymph nodes J:211773
athymia J:211773
enlarged spleen J:211773
Mmp19tm1Rase/Mmp19tm1Rase
(B6.129P2-Mmp19tm1Rase)
abnormal cytokine level J:137128
abnormal T cell activation J:137128
abnormal T cell differentiation J:137128
decreased CD4-positive, alpha-beta T cell number J:137128
decreased CD8-positive, alpha-beta T cell number J:137128
decreased inflammatory response J:137128
decreased susceptibility to type IV hypersensitivity reaction J:137128
decreased T cell proliferation J:137128
increased double-positive T cell number J:137128
Mmp20em1(IMPC)Ccpcz/Mmp20em1(IMPC)Ccpcz
(C57BL/6NCrl-Mmp20em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
Mmp24tm1Otin/Mmp24tm1Otin
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal mast cell degranulation J:153230
increased mast cell degranulation J:153230
Mmp28tm1Mani/Mmp28tm1Mani
(B6.129X1-Mmp28tm1Mani)
abnormal chemokine secretion J:145912
abnormal cytokine secretion J:145912
abnormal macrophage chemotaxis J:145912
decreased susceptibility to bacterial infection J:145912
impaired neutrophil recruitment J:145912
increased interleukin-6 secretion J:145912
increased tumor necrosis factor secretion J:145912
Mmrn1tm1b(EUCOMM)Hmgu/Mmrn1tm1b(EUCOMM)Hmgu
(C57BL/6N-Mmrn1tm1b(EUCOMM)Hmgu/Cnrm)
increased large unstained cell number J:211773
Mmuttm1Cpv/Mmuttm1Cpv
(involves: 129S/SvEv * C57BL/6 * FVB/N)
tubulointerstitial nephritis J:147313
Mmuttm1Cpv/Mmuttm1Cpv
Tg(Alb-Mut)#Cpv/0

(involves: C57BL/6)
tubulointerstitial nephritis J:200689
Mnx1tm1Jhk/Mnx1tm1Jhk
(involves: 129P2/OlaHsd)
immune system phenotype J:57314
Mnx1tm4(cre)Tmj/Mnx1+
Tardbptm1.1Ckjs/Tardbptm1.2Cjks

(involves: 129S1/Sv * C57BL/6J)
increased microglial cell activation J:190254
Mocosem2(IMPC)Ics/Mocosem2(IMPC)Ics
(involves: C57BL/6N)
kidney inflammation J:336718
tubulointerstitial nephritis J:336718
Mogtm1(cre)Gkl/Mogtm1(cre)Gkl
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(C57BL/6-Mogtm1(cre)Gkl Tg(Tcra2D2,Tcrb2D2)1Kuch)
increased susceptibility to experimental autoimmune encephalomyelitis J:151335
Mogtm1Dpd/Mogtm1Dpd
(B6.129S2-Mogtm1Dpd)
decreased susceptibility to experimental autoimmune encephalomyelitis J:85155
immune system phenotype J:85155
Mogtm1Dpd/Mogtm1Dpd
Rag2tm1Cgn/Rag2tm1Cgn
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: 129S2/SvPas * C57BL/6)
increased susceptibility to experimental autoimmune encephalomyelitis J:151335
Mogtm1Dpd/Mogtm1Dpd
Tg(H2-Kb-Tcra,-Tcrb)1640Kurs/0

(SJL.Cg-Mogtm1Dpd Tg(H2-Kb-Tcra,-Tcrb)1640Kurs)
decreased susceptibility to experimental autoimmune encephalomyelitis J:149511
Mogtm1Dpd/Mogtm1Dpd
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: 129S2/SvPas * C57BL/6)
CNS inflammation J:151335
increased susceptibility to experimental autoimmune encephalomyelitis J:151335
Mogtm1Reid/Mogtm1Reid
(B6.129S1/Sv-Mogtm1Reid)
increased susceptibility to experimental autoimmune encephalomyelitis J:86663
Mogtm1Reid/Mogtm1Reid
(129/Sv-Mogtm1Reid)
abnormal cytokine secretion J:86663
abnormal T-helper 1 physiology J:86663
increased interleukin-2 secretion J:86663
increased interleukin-6 secretion J:86663
increased susceptibility to experimental autoimmune encephalomyelitis J:86663
increased T cell proliferation J:86663
Mogat2em1(IMPC)Mbp/Mogat2em1(IMPC)Mbp
(C57BL/6N-Mogat2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Mogstm1(KOMP)Vlcg/Mogs+
(C57BL/6N-Mogstm1(KOMP)Vlcg/Bay)
absent lymph nodes J:211773
enlarged thymus J:211773
Mol1BALB/cByJ/Mol1BALB/cByJ
(involves: BALB/cByJ * C57BL/6ByJ)
decreased B cell proliferation J:58921
Mol2DBA/2N/Mol2DBA/2N
(involves: BALB/cAnFcr * DBA/2N)
increased inflammatory response J:58921
Morc2aem1(IMPC)Wtsi/Morc2aem1(IMPC)Wtsi
(C57BL/6N-Morc2aem1(IMPC)Wtsi/WtsiOulu)
abnormal thymus topology J:239583
absent connection between subcutaneous lymph vessels and lymph sac J:239583
athymia J:239583
blood in lymph vessels J:239583
small thymus J:239583
Morc3tm1b(EUCOMM)Hmgu/Morc3+
(C57BL/6N-Morc3tm1b(EUCOMM)Hmgu/Ics)
decreased lymphocyte cell number J:211773
increased large unstained cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Morc4em1(IMPC)Mbp/Y
(C57BL/6N-Morc4em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Morc4em1(IMPC)Mbp/Morc4em1(IMPC)Mbp
(C57BL/6N-Morc4em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Morf4l1tm1Kto/Morf4l1tm1Kto
(involves: 129S7/SvEvBrd)
spleen vascular congestion J:97640
Morrbidem1Flv/Morrbid+
(C57BL/6N-Morrbidem1Flv)
decreased eosinophil cell number J:236609
decreased Ly6C high monocyte number J:236609
decreased neutrophil cell number J:236609
Morrbidem1Flv/Morrbidem1Flv
(C57BL/6N-Morrbidem1Flv)
abnormal eosinophil physiology J:236609
abnormal leukocyte physiology J:236609
abnormal myelopoiesis J:236609
abnormal neutrophil physiology J:236609
decreased eosinophil cell number J:236609
decreased Ly6C high monocyte number J:236609
decreased Ly6C low monocyte number J:236609
decreased neutrophil cell number J:236609
immune system phenotype J:236609
increased susceptibility to bacterial infection J:236609
increased susceptibility to bacterial infection induced morbidity/mortality J:236609
mpc253H/mpc253H
(involves: BALB/c * C3H/HeH * C57BL/6J)
colitis J:234901
Mpdk2C57BL/6J/Mpdk2CAST/Ei
(involves: C57BL/6J * CAST/Ei)
bile duct inflammation J:99468
Mpdk2CAST/Ei/Mpdk2CAST/Ei
(involves: C57BL/6J * CAST/Ei)
bile duct inflammation J:99468
Mpdk7C57BL/6J/Mpdk7CAST/Ei
(involves: C57BL/6J * CAST/Ei)
bile duct inflammation J:99468
Mpdk7CAST/Ei/Mpdk7CAST/Ei
(involves: C57BL/6J * CAST/Ei)
bile duct inflammation J:99468
Mpdk8C57BL/6J/Mpdk8CAST/Ei
(involves: C57BL/6J * CAST/Ei)
bile duct inflammation J:99468
Mpdk8CAST/Ei/Mpdk8CAST/Ei
(involves: C57BL/6J * CAST/Ei)
bile duct inflammation J:99468
Mpeg1tm1Pod/Mpeg1+
(involves: 129X1/SvJ * C57BL/6)
abnormal susceptibility to infection induced morbidity/mortality J:269474
Mpeg1tm1Pod/Mpeg1+
(129X1/SvJ-Mpeg1tm1Pod)
abnormal susceptibility to infection induced morbidity/mortality J:269474
Mpeg1tm1Pod/Mpeg1tm1Pod
(involves: 129X1/SvJ * C57BL/6)
abnormal susceptibility to infection induced morbidity/mortality J:269474
Mpeg1tm1Pod/Mpeg1tm1Pod
(129X1/SvJ-Mpeg1tm1Pod)
abnormal susceptibility to infection induced morbidity/mortality J:269474
Mpgtm1Lds/Mpgtm1Lds
(involves: 129P2/OlaHsd * C57BL/6)
autoimmune response J:118148
decreased susceptibility to autoimmune diabetes J:118148
Mpgtm1Lds/Mpgtm1Lds
(involves: 129P2/OlaHsd)
immune system phenotype J:47993
Mpgtm1Rhe/Mpgtm1Rhe
(involves: 129P2/OlaHsd * C57BL/6J)
increased CD4-positive, alpha-beta T cell number J:70603
Mpig6btm1.1(KOMP)Vlcg/Mpig6btm1.1(KOMP)Vlcg
(C57BL/6N-Mpig6btm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Mpig6btm1.1Arte/Mpig6btm1.1Arte
(involves: C57BL/6NTac)
abnormal spleen red pulp morphology J:201266
enlarged spleen J:201266
spleen fibrosis J:201266
Mplhlb219/Mplhlb219
(C57BL/6J-Mplhlb219/J)
abnormal circulating cytokine level J:146577
decreased leukocyte cell number J:146577
enlarged spleen J:146577
Mpltm1Mwm/Mpltm1Mwm
(B6;129S2)
immune system phenotype J:83264
Mpltm1Wsa/Mpltm1Wsa
(involves: 129S1/Sv * C57BL/6)
immune system phenotype J:32131
Mpltm1Wsa/Mpltm1Wsa
(involves: 129S1/Sv)
abnormal circulating chemokine level J:162629
Mpltm1Wsa/Mpltm1Wsa
MybPlt3/Myb+

(involves: 129S1/Sv * C57BL/6)
abnormal thrombopoiesis J:89601
Mpltm1Wsa/Mpltm1Wsa
MybPlt3/MybPlt3

(involves: 129S1/Sv * C57BL/6)
abnormal B cell differentiation J:89601
abnormal spleen morphology J:89601
abnormal thrombopoiesis J:89601
decreased spleen B cell follicle size J:89601
increased spleen red pulp amount J:89601
Mpltm1Wsa/Mpltm1Wsa
MybPlt4/Myb+

(involves: 129S1/Sv * C57BL/6)
abnormal thrombopoiesis J:89601
Mpltm1Wsa/Mpltm1Wsa
MybPlt4/MybPlt4

(involves: 129S1/Sv * C57BL/6)
abnormal spleen morphology J:89601
abnormal thrombopoiesis J:89601
decreased leukocyte cell number J:89601
decreased spleen B cell follicle size J:89601
increased spleen red pulp amount J:89601
Mpltm1Wsa/Mpltm1Wsa
Suz12Gt(Betageo)1Khe/Suz12+

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
abnormal thrombopoiesis J:136262
increased leukocyte cell number J:136262
increased lymphocyte cell number J:136262
Mpltm1Wsa/Mpltm1Wsa
Suz12Plt8/Suz12+

(B6.Cg-Mpltm1Wsa Suz12Plt8)
abnormal thrombopoiesis J:136262
increased leukocyte cell number J:136262
increased lymphocyte cell number J:136262
Mpltm2.1Wsa/Mpltm2.1Wsa
Tg(Pf4-icre)Q3Rsko/0

(involves: C57BL/6)
enlarged spleen J:208120
Mpotm1Lus/Mpotm1Lus
(involves: 129X1/SvJ * C57BL/6J)
abnormal neutrophil physiology J:67586
decreased inflammatory response J:102688
increased monocyte cell number J:67586
increased susceptibility to experimental autoimmune encephalomyelitis J:102965
increased susceptibility to fungal infection J:67586
sepsis J:126649
Mpotm1Lus/Mpotm1Lus
(B6.129X1-Mpotm1Lus)
abnormal neutrophil physiology J:112488
Mpotm1Mae/Mpotm1Mae
(involves: 129P2/OlaHsd * C57BL/6)
abnormal neutrophil physiology J:53993
increased susceptibility to fungal infection J:53993
Mpp1tm1Ahc/Mpp1tm1Ahc
(B6.129-Mpp1tm1Ahc)
abnormal neutrophil physiology J:154749
impaired neutrophil chemotaxis J:154749
Mpped2em1(IMPC)J/Mpped2em1(IMPC)J
(C57BL/6NJ-Mpped2em1(IMPC)J/J)
increased leukocyte cell number J:211773
Mptx2em1Yoxi/Mptx2em1Yoxi
(C57BL/6J-Mptx2em1Yoxi)
increased susceptibility to bacterial infection J:326562
Mpv17l2tm1.1(KOMP)Mbp/Mpv17l2tm1.1(KOMP)Mbp
(C57BL/6N-Mpv17l2tm1.1(KOMP)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Mpzem1(IMPC)Tcp/Mpzem1(IMPC)Tcp
(C57BL/6NCrl-Mpzem1(IMPC)Tcp/Tcp)
increased neutrophil cell number J:211773
Mpztm1Msch/Mpz+
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal cytokine secretion J:82432
abnormal macrophage chemotaxis J:67581
abnormal T-helper 1 physiology J:82432
increased monocyte cell number J:82432
Mpztm1Msch/Mpz+
(involves: 129S7/SvEvBrd)
increased macrophage cell number J:133028
Mpztm1Msch/Mpz+
(B6.129S7-Mpztm1Msch)
autoimmune response J:59319
Mpztm1Msch/Mpz+
Rag1tm1Mom/Rag1tm1Mom

(B6.129S7-Mpztm1Msch Rag1tm1Mom)
absent CD4-positive, alpha-beta T cells J:59319
absent CD8-positive, alpha-beta T cells J:59319
Mpztm1Msch/Mpz+
Tcratm1Mjo/Tcratm1Mjo

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * BALB/c * C57BL/6)
decreased T cell number J:59319
Mpzl2tm1Lex/Mpzl2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased B cell number J:171883
increased CD8-positive, alpha-beta T cell number J:171883
Mpzl3rc/Mpzl3rc
(C57BL/6J-Mpzl3rc/J)
abnormal spleen morphology J:93038
dermatitis J:93038
liver inflammation J:93038
Mpzl3tm1(KOMP)Mbp/Mpzl3tm1(KOMP)Mbp
(C57BL/6-Tyrc-Brd Mpzl3tm1(KOMP)Mbp)
seborrheic dermatitis J:210832
skin inflammation J:210832
Mr1tm1Gfn/Mr1tm1Gfn
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal B cell physiology J:113083
abnormal T cell number J:113083
Mr1tm1Gfn/Mr1tm1Gfn
(B6.129P2-Mr1tm1Gfn)
increased susceptibility to experimental autoimmune encephalomyelitis J:112657
Mr1tm1Gfn/Mr1tm1Gfn
(involves: 129P2/OlaHsd)
abnormal susceptibility to bacterial infection J:276912
MrasGt(OST108223)Lex/MrasGt(OST108223)Lex
(B6;129S5-MrasGt(OST108223)Lex/Ieg)
decreased B cell number J:82809
Mrc1tm1Mnz/Mrc1tm1Mnz
(involves: 129P2/OlaHsd)
abnormal macrophage physiology J:124290
Mrc1tm1Mnz/Mrc1tm1Mnz
(B6.129P2-Mrc1tm1Mnz)
decreased susceptibility to parasitic infection J:194065
decreased susceptibility to parasitic infection induced morbidity/mortality J:194065
decreased T cell number J:194065
increased granulocyte number J:194065
Mrc1tm1Mnz/Mrc1tm1Mnz
Mrc2tm1Cmi/Mrc2tm1Cmi

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ)
abnormal macrophage physiology J:124290
Mre11atm1.1Rchd/Mre11atm1.1Rchd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal class switch recombination J:184053
Mregtm1b(EUCOMM)Hmgu/Mregtm1b(EUCOMM)Hmgu
(C57BL/6N-Mregtm1b(EUCOMM)Hmgu/Kmpc)
abnormal lymph node morphology J:211773
Mrfap1tm1Kto/Mrfap1tm1Kto
(involves: 129S7/SvEvBrd * C57BL/6J)
immune system phenotype J:92967
Mrgprb2em1(IMPC)Tcp/Mrgprb2em1(IMPC)Tcp
(C57BL/6NCrl-Mrgprb2em1(IMPC)Tcp/Tcp)
small spleen J:211773
Mrgprb2em1Xzd/Mrgprb2em1Xzd
(C57BL/6-Mrgprb2em1Xzd)
decreased inflammatory response J:219209
decreased mast cell degranulation J:219209
immune system phenotype J:219209
Mri1em1(IMPC)Bay/Mri1em1(IMPC)Bay
(C57BL/6N-Mri1em1(IMPC)Bay/BayMmucd)
increased spleen weight J:211773
Mrpl12em1(IMPC)Tcp/Mrpl12+
(C57BL/6NCrl-Mrpl12em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Mrps22tm1.1(KOMP)Vlcg/Mrps22+
(C57BL/6N-Mrps22tm1.1(KOMP)Vlcg/J)
increased leukocyte cell number J:211773
Mrs2em1Muma/Mrs2em1Muma
(B6.Cg-Mrs2em1Muma)
decreased susceptibility to endotoxin shock J:298361
Ms4a1tm1Msn/Ms4a1tm1Msn
(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:48688
Ms4a1tm1Tft/Ms4a1tm1Tft
(involves: 129 * C57BL/6)
abnormal B cell number J:88933
abnormal B cell physiology J:88933
decreased B-1 B cell number J:88933
immune system phenotype J:88933
increased transitional stage B cell number J:88933
Ms4a2tm1Chr/Ms4a2tm1Chr
(involves: 129S1/Sv * 129X1/SvJ)
abnormal mast cell physiology J:53106
decreased susceptibility to type I hypersensitivity reaction J:53106
Ms4a2tm1Knt/Ms4a2tm1Knt
(involves: 129 * BALB/c)
abnormal cytokine secretion J:47138
abnormal mast cell physiology J:47138
decreased susceptibility to type I hypersensitivity reaction J:47138
Ms4a2tm1Knt/Ms4a2tm1Knt
Tg(SV40/HTLV-FCER1A)1Bhk/0

(involves: 129 * BALB/c)
abnormal cytokine secretion J:47138
abnormal mast cell physiology J:47138
decreased susceptibility to type I hypersensitivity reaction J:47138
Ms4a4aem1Wwz/Ms4a4aem1Wwz
(C57BL/6NCrl-Ms4a4aem1Wwz)
abnormal macrophage physiology J:296429
decreased eosinophil cell number J:296429
decreased interleukin-4 secretion J:296429
decreased interleukin-13 secretion J:296429
impaired eosinophil recruitment J:296429
Ms4a6dem1Cya/Ms4a6dem1Cya
(involves: C57BL/6)
decreased susceptibility to endotoxin shock J:342776
Ms4a6dem1Ywch/Ms4a6dem1Ywch
(C57BL/6-Ms4a6dem1Ywch)
decreased susceptibility to endotoxin shock J:342776
Ms4a6dem2Ywch/Ms4a6dem2Ywch
(C57BL/6-Ms4a6dem2Ywch)
decreased susceptibility to endotoxin shock J:342776
Ms4a12em1(IMPC)Mbp/Ms4a12em1(IMPC)Mbp
(C57BL/6N-Ms4a12em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Msantd3em1(IMPC)J/Msantd3em1(IMPC)J
(C57BL/6NJ-Msantd3em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Msh2tm1Htr/Msh2tm1Htr
(involves: 129P2/OlaHsd)
abnormal class switch recombination J:80893
abnormal inflammatory response J:80893
abnormal somatic hypermutation frequency J:155454
decreased IgG1 level J:80893
decreased IgG3 level J:80893
immune system phenotype J:47993
Msh2tm1Htr/Msh2tm1Htr
Pcnatm1Jcbs/Pcnatm1Jcbs

(involves: 129P2/OlaHsd)
abnormal somatic hypermutation frequency J:155454
Msh2tm1Mak/Msh2tm1Mak
(involves: 129P2/OlaHsd * C57BL/6J)
immune system phenotype J:28397
Msh2tm1Mak/Msh2tm1Mak
(C57BL/6NTac-Msh2tm1Mak)
abnormal class switch recombination J:326431
abnormal somatic hypermutation frequency J:326431
Msh2tm1Rak/Msh2tm1Rak
(involves: 129P2/OlaHsd)
abnormal class switch recombination J:56764
decreased mature B cell number J:56764
Msh2tm1Wed/Msh2tm1Wed
(involves: C57BL/6)
abnormal class switch recombination J:86278
decreased IgG level J:86278
Msh5tm1b(EUCOMM)Wtsi/Msh5tm1b(EUCOMM)Wtsi
(C57BL/6N-Msh5tm1b(EUCOMM)Wtsi/Ieg)
increased leukocyte cell number J:211773
Msh6m1Btlr/Msh6m1Btlr
(C57BL/6J-Msh6m1Btlr)
decreased IgE level J:255208
Msi2em1(IMPC)Mbp/Msi2em1(IMPC)Mbp
(C57BL/6N-Msi2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased neutrophil cell number J:211773
decreased spleen weight J:211773
small spleen J:211773
Msi2Gt(E035H03)Wrst/Msi2Gt(E035H03)Wrst
(B6.129P2-Msi2Gt(E035H03)Wrst)
abnormal myeloid leukocyte morphology J:174870
decreased B cell number J:174870
decreased CD4-positive, alpha-beta T cell number J:174870
decreased CD8-positive, alpha-beta T cell number J:174870
decreased DN2 thymocyte number J:174870
decreased DN3 thymocyte number J:174870
decreased double-negative T cell number J:174870
decreased double-positive T cell number J:174870
decreased granulocyte number J:174870
decreased immature B cell number J:174870
decreased leukocyte cell number J:174870
decreased macrophage cell number J:174870
decreased mature B cell number J:174870
decreased pre-B cell number J:174870
small spleen J:174870
small thymus J:174870
spleen hypoplasia J:174870
thymus hypoplasia J:174870
Msi2tm1.1Cjl/Msi2tm1.1Cjl
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
decreased spleen weight J:208349
immune system phenotype J:208349
spleen hypoplasia J:208349
Msmbtm1Xuan/Msmbtm1Xuan
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * CD-1))
enlarged lymph nodes J:96884
Msmpem1Jzx/Msmpem1Jzx
(C57BL/6-Msmpem1Jzx)
abnormal macrophage differentiation J:311042
decreased circulating interleukin-6 level J:311042
decreased circulating tumor necrosis factor level J:311042
liver inflammation J:311042
Msntm1b(EUCOMM)Hmgu/Msntm1b(EUCOMM)Hmgu
(C57BL/6N-Msntm1b(EUCOMM)Hmgu/J)
decreased leukocyte cell number J:211773
Msntm1Sts/Y
(involves: 129S4/SvJae * C57BL/6)
decreased B cell number J:189837
decreased CD4-positive, alpha-beta T cell number J:189837
decreased eosinophil cell number J:189837
decreased lymphocyte cell number J:189837
decreased neutrophil cell number J:189837
impaired leukocyte migration J:189837
Msr1tm1Csk/Msr1tm1Csk
(involves: 129X1/SvJ * ICR)
increased interleukin-12 secretion J:110433
increased susceptibility to bacterial infection induced morbidity/mortality J:39079
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:39079
Msr1tm1Csk/Msr1tm1Csk
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal macrophage physiology J:91911
Msr1tm1Csk/Msr1tm1Csk
(B6.129X1-Msr1tm1Csk)
decreased interferon-beta secretion J:251008
Msr1tm1Csk/Msr1tm1Csk
Scarf1tm1Ishi/Scarf1tm1Ishi

(involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J)
abnormal macrophage physiology J:91911
Mst1tm1Jab/Mst1tm1Jab
(involves: 129P2/OlaHsd * Black Swiss)
abnormal macrophage physiology J:46185
immune system phenotype J:46185
increased susceptibility to induced colitis J:46185
Mst1rFv2-s/Mst1rFv2-s
(B6.DDD-Mst1rFv2-s)
enlarged spleen J:5120
increased susceptibility to Retroviridae infection J:5120
Mst1rFv2-s/Mst1rFv2-s
(either: A/Crgl or C57BL/Crgl)
decreased susceptibility to Retroviridae infection J:167666
Mst1rFv2-s/Mst1rFv2-s
(either: BALB/cCrgl or DBA/2Crgl or Swiss)
enlarged spleen J:167666
increased susceptibility to Retroviridae infection J:167666
Mst1rFv2-s/Mst1rFv2-s
(C3H/Crgl)
increased susceptibility to Retroviridae infection J:167666
Mst1rtm1.1Sew/Mst1rtm1.1Sew
(involves: 129/Ola * CD-1 * NIH Black Swiss)
abnormal macrophage physiology J:75503
abnormal type IV hypersensitivity reaction J:75503
increased acute inflammation J:75503
increased susceptibility to endotoxin shock J:75503
Mst1rtm1Ber/Mst1rtm1Ber
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal macrophage physiology J:76451
abnormal type IV hypersensitivity reaction J:76451
immune system phenotype J:76451
increased inflammatory response J:76451
increased susceptibility to bacterial infection J:76451
Mst1rtm1Sjd/Mst1r+
(either: (involves: 129 * C57BL/6) or (involves: 129 * CD-1) or (involves: 129 * NIH Black Swiss))
abnormal macrophage physiology J:54903
increased susceptibility to bacterial infection J:54903
Mst1rtm2(Mst1r*)Sew/Mst1rtm2(Mst1r*)Sew
(involves: 129P2/OlaHsd * Black Swiss * FVB/N)
decreased spleen weight J:215969
increased susceptibility to Retroviridae infection J:215969
Mst1rtm2(Mst1r*)Sew/Mst1rtm2(Mst1r*)Sew
(FVB.129P2(Cg)-Mst1rtm2(Mst1r*)Sew)
increased circulating interferon-gamma level J:215969
increased interferon-gamma secretion J:215969
Mstnlean/Mstnlean
(C57BL/6J-Mstnlean)
abnormal circulating tumor necrosis factor level J:146513
decreased circulating tumor necrosis factor level J:146513
Msto1em1(IMPC)Tcp/Msto1+
(C57BL/6N-Msto1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
small spleen J:211773
Msx1tm1Rilm/Msx1+
Pax9tm1Rbal/Pax9tm1Rbal

(involves: 129 * CD-1)
ectopic thymus J:311535
thymus hypoplasia J:311535
Msx2tm1Rilm/Msx2tm1Rilm
(either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J))
decreased osteoclast cell number J:61509
Mt1tm1Bri/Mt1tm1Bri
Mt2tm1Bri/Mt2tm1Bri

(involves: 129S7/SvEvBrd)
abnormal microglial cell morphology J:103102, J:53929
abnormal microglial cell physiology J:53929
increased interleukin-1 beta secretion J:103102
increased interleukin-6 secretion J:103102
increased macrophage cell number J:53929
increased susceptibility to experimental autoimmune encephalomyelitis J:103102
increased tumor necrosis factor secretion J:103102
Mt1tm1Bri/Mt1tm1Bri
Mt2tm1Bri/Mt2tm1Bri

(129S7/SvEvBrd-Mt1tm1Bri Mt2tm1Bri/J)
abnormal humoral immune response J:110643
abnormal lymphocyte physiology J:110643
abnormal microglial cell morphology J:89429
decreased B cell number J:110643
decreased T cell number J:110643
enlarged spleen J:110643
increased CD4-positive, alpha-beta T cell number J:110643
increased CD8-positive, alpha-beta T cell number J:110643
increased IgG level J:110643
increased IgM level J:110643
increased lymphocyte cell number J:110643
increased neutrophil cell number J:120196
increased plasma cell number J:110643
increased spleen weight J:110643
increased thymocyte apoptosis J:57169
kidney inflammation J:126620
lung inflammation J:120196
spleen hyperplasia J:110643
mt-Co1m1Jiha
(involves: C57BL/6J * M. m. domesticus)
heart inflammation J:132659
mt-Nd2m1
(ALR/Lt)
decreased susceptibility to autoimmune diabetes J:117602, J:97969
Mta2tm1.1Yzha/Mta2tm1.1Yzha
(involves: 129S4/SvJae * C57BL/6 * FVB/N)
dermatitis J:137101
glomerulonephritis J:137101
increased anti-double stranded DNA antibody level J:137101
increased autoantibody level J:137101
increased circulating interferon-gamma level J:137101
increased circulating interleukin-2 level J:137101
increased circulating interleukin-4 level J:137101
increased susceptibility to systemic lupus erythematosus J:137101
increased T cell proliferation J:137101
liver inflammation J:137101
panniculitis J:137101
skin inflammation J:137101
Mta2tm1Yzha/Mta2tm1Yzha
Tg(Lck-cre)#Zhu/0

(involves: 129S4/SvJae * C57BL/6 * SJL)
immune system phenotype J:137101
increased T cell proliferation J:137101
Mtapem1(IMPC)Mbp/Mtap+
(C57BL/6N-Mtapem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
MtapGt(RRK081)Byg/Mtap+
(129P2/OlaHsd-MtapGt(RRK081)Byg)
arteritis J:123675
Mtarc1em1(IMPC)H/Mtarc1em1(IMPC)H
(C57BL/6NTac-Mtarc1em1(IMPC)H/H)
increased spleen weight J:211773
Mtbcq2NMRI8/Fbn/?
(involves: DBA/2OlaHsd * NMRI8/Fbn)
increased spleen weight J:122125
Mtch2tm1b(EUCOMM)Hmgu/Mtch2+
(C57BL/6N-Mtch2tm1b(EUCOMM)Hmgu/Cnrm)
increased monocyte cell number J:211773
Mtdhtm1.2Dsar/Mtdhtm1.2Dsar
(either: B6.129(FVB)-Mtdhtm1.2Dsar or (129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N))
decreased interleukin-1 beta secretion J:216688
decreased interleukin-6 secretion J:216688
decreased macrophage proliferation J:216688
Mtf1tm1Wsc/Mtf1tm1Wsc
Tg(Mx1-cre)1Cgn/0
Tg(UBC-Mtf1)1Wsc/0

(involves: 129/Sv * C57BL/6 * CBA)
decreased leukocyte cell number J:91119
decreased lymphocyte cell number J:91119
Mtgq4NMRI8/Fbn/?
(involves: DBA/2OlaHsd * NMRI8/Fbn)
increased spleen weight J:122125
Mthfd1tm1.1Rzn/Mthfd1+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N)
decreased leukocyte cell number J:199578
decreased neutrophil cell number J:199578
Mtmr4tm1a(EUCOMM)Wtsi/Mtmr4+
(Not Specified)
decreased IgE level J:165965
Mtmr11em1(IMPC)Tcp/Mtmr11em1(IMPC)Tcp
(C57BL/6NCrl-Mtmr11em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Mtorchino/Mtorchino
(involves: C57BL/6JAnu)
decreased CD4-positive, alpha-beta T cell number J:207898
decreased splenocyte number J:207898
immune system phenotype J:207898
Mtorchino/Mtorchino
Rasgrp1m1Anu/Rasgrp1m1Anu

(involves: C57BL/6JAnu * C57BL/6JSfdAnu * CBA/J)
immune system phenotype J:207898
Mtortm1.1Lgm/Mtortm1.1Lgm
(involves: 129S1/Sv * C57BL/6)
immune system phenotype J:168600
Mtortm1.2Koz/Mtortm1.2Koz
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJae * C57BL/6 * DBA/2)
abnormal T cell differentiation J:150108
abnormal T cell subpopulation ratio J:150108
abnormal thymus cell ratio J:150108
decreased interferon-gamma secretion J:150108
decreased interleukin-2 secretion J:150108
decreased interleukin-17 secretion J:150108
decreased T cell proliferation J:150108
decreased tumor necrosis factor secretion J:150108
increased regulatory T cell number J:150108
Mtortm1Lgm/Mtortm1Lgm
(involves: 129S1/Sv * C57BL/6)
abnormal B cell differentiation J:168600
abnormal B cell physiology J:168600
abnormal humoral immune response J:168600
abnormal T cell morphology J:168600
abnormal T cell physiology J:168600
decreased B cell number J:168600
decreased B cell proliferation J:168600
decreased double-positive T cell number J:168600
decreased follicular B cell number J:168600
decreased IgG level J:168600
decreased IgM level J:168600
decreased marginal zone B cell number J:168600
decreased monocyte cell number J:168600
decreased neutrophil cell number J:168600
decreased plasma cell number J:168600
decreased splenocyte apoptosis J:168600
decreased splenocyte proliferation J:168600
decreased thymocyte number J:168600
decreased transitional stage T1 B cell number J:168600
increased CD4-positive, alpha-beta T cell number J:168600
increased CD8-positive, alpha-beta T cell number J:168600
small spleen J:168600
Mtss1Gt(CSC156)Byg/Mtss1Gt(CSC156)Byg
(B6.129P2-Mtss1Gt(CSC156)Byg)
abnormal B cell differentiation J:186118
abnormal B cell number J:186118
abnormal B cell physiology J:186118
decreased immature B cell number J:186118
enlarged spleen J:186118
increased inflammatory response J:186118
increased leukocyte cell number J:186118
increased pre-B cell number J:186118
Mtus1Gt(RRA048)Byg/Mtus1Gt(RRA048)Byg
(involves: 129P2/OlaHsd * C57BL/6)
glomerulonephritis J:212144
increased leukocyte cell number J:212144
increased lymphocyte cell number J:212144
increased susceptibility to systemic lupus erythematosus J:212144
insulitis J:212144
lymphoid hyperplasia J:212144
salivary gland inflammation J:212144
Mtv7BALB/c/Mtv7BALB/c
(involves: B10.Q * BALB/c * DBA/2)
increased susceptibility to induced arthritis J:27701
Mtv7BALB/c/Mtv7DBA/2
(involves: B10.Q * BALB/c * DBA/2)
decreased susceptibility to induced arthritis J:27701
Mtv7DBA/2/Mtv7DBA/2
(C.D2-Mtv7DBA/2)
decreased susceptibility to induced arthritis J:27701
Mtx2em1(IMPC)J/Mtx2+
(C57BL/6NJ-Mtx2em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Muc2eey/Muc2eey
(C57BL/6-Muc2eey)
ileum inflammation J:194148
increased interferon-gamma secretion J:194148
increased interleukin-1 beta secretion J:194148
increased leukocyte cell number J:194148
increased susceptibility to induced colitis J:194148
increased tumor necrosis factor secretion J:194148
Muc2keny/Muc2keny
(C57BL/6JAnu-Muc2keny/AnuApb)
enlarged lymph nodes J:104190
Muc2M1Btlr/Muc2+
(C57BL/6J-Muc2M1Btlr)
increased susceptibility to induced colitis J:150326
Muc2M1Btlr/Muc2M1Btlr
(C57BL/6J-Muc2M1Btlr)
increased susceptibility to induced colitis J:150326
Muc2m2Btlr/?
(C57BL/6J-Muc2m2Btlr)
increased susceptibility to induced colitis J:159359
Muc2m3Btlr/Muc2m3Btlr
(C57BL/6J-Muc2m3Btlr)
increased susceptibility to induced colitis J:254906
Muc2tm1Avel/Muc2tm1Avel
(involves: 129P2/OlaHsd * C57BL/6)
colitis J:216831
large intestinal inflammation J:216831
Muc2wnn/Muc2+
(C57BL/6-Muc2wnn)
increased susceptibility to induced colitis J:194148
Muc2wnn/Muc2wnn
(C57BL/6-Muc2wnn)
colitis J:194148
ileum inflammation J:194148
increased interferon-gamma secretion J:194148
increased interleukin-1 beta secretion J:194148
increased interleukin-13 secretion J:194148
increased leukocyte cell number J:194148
increased lymphocyte cell number J:194148
increased susceptibility to induced colitis J:194148
increased tumor necrosis factor secretion J:194148
Muc4PWK/PhJ/Muc4PWK/PhJ
(PWK/PhJ)
abnormal susceptibility to viral infection J:287566
Muc4tm1Skb/Muc4tm1Skb
(involves: 129 * C57BL/6J)
decreased susceptibility to colitis induced morbidity/mortality J:234205
decreased susceptibility to induced colitis J:234205
Muc4tm1Unc/Muc4tm1Unc
(B6NTac.129(FVB)-Muc4tm1Unc/Rand)
increased susceptibility to Coronaviridae infection J:287566
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:287566
increased susceptibility to Togaviridae infection J:287566
Muc5actm1.1Evns/Muc5actm1.1Evns
(B6.129S1-Muc5actm1.1Evns)
increased circulating interferon-gamma level J:177306
increased susceptibility to parasitic infection J:177306
Muc5btm1.2Evns/Muc5btm1.2Evns
(B6.129S1-Muc5btm1.2Evns)
abnormal professional antigen presenting cell physiology J:207159
decreased interleukin-23 secretion J:207159
impaired macrophage phagocytosis J:207159
increased macrophage apoptosis J:207159
increased susceptibility to bacterial infection J:207159
increased susceptibility to bacterial infection induced morbidity/mortality J:207159
increased susceptibility to otitis media J:207159
respiratory system inflammation J:207159
sepsis J:207159
Muc13tm1.1Mamg/Muc13tm1.1Mamg
(involves: 129 * C57BL/6)
increased susceptibility to colitis induced morbidity/mortality J:313870
increased susceptibility to induced colitis J:313870
large intestinal inflammation J:313870
small intestinal inflammation J:313870
Muc19sld/Muc19sld
(NFS/N-Muc19sld)
increased susceptibility to autoimmune disorder J:216958, J:20364
Mug1tm1Vln/Mug1tm1Vln
(B.129P2-Mug1tm1Vln)
abnormal cytokine level J:57485
liver inflammation J:57485
Mug1tm2Vln/Mug1tm2Vln
Pzptm1Vln/Pzptm1Vln

(B.129P2-Pzptm1Vln Mug1tm2Vln)
abnormal cytokine level J:57485
abnormal uterine NK cell morphology J:117841
liver inflammation J:57485
Mul1em1(IMPC)H/Mul1em1(IMPC)H
(C57BL/6N-Mul1em1(IMPC)H/H)
decreased spleen weight J:211773
small thymus J:211773
Mus81tm1Esse/Mus81+
(involves: 129P2/OlaHsd * C57BL/6J)
increased inflammatory response J:222498
Mus81tm1Esse/Mus81tm1Esse
(involves: 129P2/OlaHsd * C57BL/6J)
increased interleukin-1 beta secretion J:222498
lung inflammation J:222498
Mus81tm1Raz/Mus81tm1Raz
(involves: 129P2/OlaHsd)
immune system phenotype J:91570
Mx1r/Mx1r
(B6.A2G-Mx1r)
abnormal susceptibility to infection J:120938
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:23752
Mx1r/Mx1r
(C.A2G-Mx1r)
decreased susceptibility to Orthomyxoviridae infection J:23752
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:23752
Mx1r/Mx1r
(A2G)
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:23752
Mx1s1/Mx1s1
(BALB/c)
increased susceptibility to Orthomyxoviridae infection J:23752
Mx1s1/Mx1s1
(C57BL/6)
abnormal peritoneal macrophage morphology J:23752
abnormal susceptibility to infection J:120938
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:23752
Mx1s1/Mx1s1
Tg(Hmgcr-MX1)LStae/?

(involves: C57BL/6 * SJL)
decreased susceptibility to Orthomyxoviridae infection J:128067
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:128067
decreased susceptibility to Riboviria infection J:128067
decreased susceptibility to Riboviria infection induced morbidity/mortality J:128067
Mx1s2/Mx1s2
(CBA/J)
increased susceptibility to Orthomyxoviridae infection J:23752
Mxd1tm1Rne/Mxd1tm1Rne
(involves: 129S4/SvJaeSor * C57BL/6)
abnormal B cell physiology J:45945
abnormal myeloid leukocyte morphology J:45945
immune system phenotype J:45945
increased granulocyte number J:45945
Mxi1tm1Rdp/Mxi1tm1Rdp
(involves: 129/Sv * C57BL/6J * SJL)
abnormal lymphocyte morphology J:48236
enlarged spleen J:48236
increased spleen white pulp amount J:48236
increased T cell proliferation J:48236
Mxra8em1Diam/Mxra8+
(C57BL/6J-Mxra8em1Diam)
decreased susceptibility to Togaviridae infection J:280585
Mxra8em1Diam/Mxra8em1Diam
(C57BL/6J-Mxra8em1Diam)
abnormal cytokine level J:280585
decreased inflammatory response J:280585
decreased susceptibility to Togaviridae infection J:280585
Mxra8em2Diam/Mxra8em2Diam
(C57BL/6J-Mxra8em2Diam)
decreased susceptibility to Togaviridae infection J:280585
Mybboo/Mybboo
(involves: C57BL/6)
abnormal B cell differentiation J:167270
abnormal leukocyte morphology J:167270
abnormal spleen morphology J:167270
decreased neutrophil cell number J:167270
decreased spleen white pulp amount J:167270
enlarged spleen J:167270
increased spleen red pulp amount J:167270
MybM303V/MybM303V
(involves: 129S1/SvlmJ * C57BL/6)
arrested B cell differentiation J:96507
arrested T cell differentiation J:96507
decreased B cell number J:96507
decreased eosinophil cell number J:96507
decreased single-positive T cell number J:96507
decreased thymocyte number J:96507
Mybtm1.1Cgn/Myb+
(involves: 129P2/OlaHsd * C57BL/6)
arrested B cell differentiation J:127234
decreased B-1 B cell number J:127234
decreased mature B cell number J:127234
decreased pre-B cell number J:127234
Mybtm1Cgn/Mybtm1.1Cgn
Tg(Lck-cre)548Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:91122
decreased double-positive T cell number J:91122
thymus hypoplasia J:91122
Mybtm1Cgn/Mybtm1Cgn
Tg(Lck-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
arrested T cell differentiation J:91122
decreased CD4-positive, alpha-beta T cell number J:91122
decreased CD8-positive, alpha-beta T cell number J:91122
decreased double-negative T cell number J:91122
decreased double-positive T cell number J:91122
decreased gamma-delta T cell number J:91122
thymus hypoplasia J:91122
Mybtm1Cgn/Mybtm1Cgn
Tg(Lck-cre)548Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:91122
decreased double-positive T cell number J:91122
thymus hypoplasia J:91122
Mybtm1Epr/Mybtm1Epr
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal T cell differentiation J:93481
decreased CD4-positive, alpha-beta T cell number J:93481
decreased double-positive T cell number J:93481
increased CD8-positive, alpha-beta T cell number J:93481
thymus hypoplasia J:93481
Mybtm1Epr/Mybtm1Epr
Tg(Lck-cre)548Jxm/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal double-negative T cell morphology J:93481
abnormal T cell differentiation J:93481
decreased double-positive T cell number J:93481
thymus hypoplasia J:93481
Mybtm1Jof/Mybtm1Jof
(involves: 129/Sv * C57BL/6)
abnormal B cell differentiation J:85344
abnormal double-negative T cell morphology J:85344
abnormal T cell differentiation J:85344
decreased thymocyte number J:85344
Mybtm1Jof/Mybtm1Ssp
(involves: 129/Sv * C57BL/6)
abnormal T cell differentiation J:85344
decreased thymocyte number J:85344
Mybtm2.2Epr/Mybtm2.2Epr
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:160189
Mybl1tm1Epr/Mybl1tm1Epr
(involves: 129 * C57BL/6)
abnormal humoral immune response J:67604
abnormal spleen B cell follicle morphology J:67604
abnormal spleen marginal zone morphology J:67604
decreased B cell number J:67604
decreased IgG1 level J:67604
decreased IgG2a level J:67604
decreased IgG3 level J:67604
decreased spleen germinal center number J:67604
increased spleen red pulp amount J:67604
small spleen J:67604
spleen hypoplasia J:67604
Mybl2tm1.1Epr/Mybl2tm1.1Epr
Tg(Mx1-cre)1Cgn/0

(involves: 129X1/SvJ * C57BL/6 * CBA * FVB/N)
abnormal myelopoiesis J:206816
decreased B cell number J:206816
decreased leukocyte cell number J:206816
decreased lymphocyte cell number J:206816
decreased neutrophil cell number J:206816
decreased splenocyte number J:206816
decreased T cell number J:206816
Mybl2tm1.1Jof/Mybl2+
Tg(Zp3-cre)3Mrt/0

(involves: 129S2/SvPas * C57BL/6 * FVB/N)
abnormal myelopoiesis J:196804
decreased leukocyte cell number J:196804
decreased neutrophil cell number J:196804
enlarged spleen J:196804
increased granulocyte number J:196804
increased leukocyte cell number J:196804
increased monocyte cell number J:196804
myeloid hyperplasia J:196804
Mybphltm1a(KOMP)Wtsi/Mybphltm1a(KOMP)Wtsi
(C57BL/6N-Mybphltm1a(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
Mybphltm1b(KOMP)Wtsi/Mybphltm1b(KOMP)Wtsi
(C57BL/6N-Mybphltm1b(KOMP)Wtsi/Wtsi)
abnormal thymus morphology J:239583
blood in lymph vessels J:239583
Myctm1.1(Nmyc1)Fwa/Myctm1.1(Nmyc1)Fwa
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:62573
Myctm1.1Cksn/Myctm1.1Cksn
(B6.129-Myctm1.1Cksn)
immune system phenotype J:170508
Myctm1Atp/Myc+
(involves: 129P2/OlaHsd * FVB/N)
decreased T cell proliferation J:73369
lymph node hypoplasia J:73369
lymphoid hypoplasia J:73369
small lymphoid organs J:73369
spleen hypoplasia J:73369
Myctm1Atp/Myc+
(B6.129P2-Myctm1Atp)
abnormal NK cell physiology J:132730
decreased memory T cell number J:132730
decreased T cell proliferation J:132730
immune system phenotype J:132730
Myctm1Atp/Myctm2.1Atp
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL)
decreased T cell proliferation J:73369
immune system phenotype J:73369
lymph node hypoplasia J:73369
spleen hypoplasia J:73369
Myctm1Atp/Myctm2.1Atp
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N * SJL)
immune system phenotype J:73369
Myctm1Lbox/Myc+
(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
enlarged lymph nodes J:97900
enlarged spleen J:97900
increased B cell number J:97900
increased spleen weight J:97900
Myctm1Lbox/Myctm1Lbox
(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
decreased T cell number J:97900
enlarged lymph nodes J:97900
enlarged spleen J:97900
increased B cell apoptosis J:97900
increased B cell number J:97900
increased B cell proliferation J:97900
increased spleen weight J:97900
Myctm2.1Atp/Myc+
(involves: 129P2/OlaHsd * C57BL/6 * SJL)
decreased T cell proliferation J:73369
Myctm2.1Atp/Myctm2.1Atp
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N * SJL)
immune system phenotype J:73369
Myctm2Fwa/Myctm2Fwa
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
decreased B cell proliferation J:67222
Myctm3(Tcrb)Fwa/Myc+
(involves: 129)
abnormal T cell receptor beta chain V(D)J recombination J:131995
Mycltm1.1Kmm/Mycltm1.1Kmm
(B6.129S6(C)-Mycltm1.1Kmm)
abnormal dendritic cell physiology J:206430
decreased dendritic cell number J:206430
decreased susceptibility to bacterial infection induced morbidity/mortality J:206430
Myct1em1(IMPC)Mbp/Myct1em1(IMPC)Mbp
(C57BL/6N-Myct1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Myct1em1Choi/Myct1em1Choi
(involves: C57BL/6)
abnormal macrophage cell number J:303692
decreased regulatory T cell number J:303692
increased CD8-positive, alpha-beta T cell number J:303692
Myd88lkd/Myd88lkd
(C57BL/6-Myd88lkd)
abnormal adaptive immunity J:110094
abnormal cell-mediated immunity J:110094
abnormal innate immunity J:110094
abnormal macrophage physiology J:110094
immune system phenotype J:110094
Myd88m3Btlr/Myd88m3Btlr
(C57BL/6J-Myd88m3Btlr)
immune system phenotype J:156848
Myd88M4Btlr/Myd88+
(C57BL/6J-Myd88M4Btlr)
decreased tumor necrosis factor secretion J:254917
Myd88M4Btlr/Myd88M4Btlr
(C57BL/6J-Myd88M4Btlr)
decreased tumor necrosis factor secretion J:254917
Myd88poc/Myd88+
(C57BL/6-Myd88poc)
immune system phenotype J:110094
Myd88poc/Myd88poc
(C57BL/6-Myd88poc)
abnormal immune system physiology J:110094
abnormal macrophage physiology J:110094
immune system phenotype J:110094
increased susceptibility to bacterial infection J:110094
increased susceptibility to Herpesvirales infection J:110094
Myd88poc/Myd88poc
Ptpn6m1Btlr/Ptpn6m1Btlr

(C57BL/6J-Ptpn6m1Btlr Myd88poc)
immune system phenotype J:142845
Myd88tm1.1Defr/Myd88tm1.1Defr
(B6.129P2(SJL)-Myd88tm1.1Defr)
abnormal CD4-positive, alpha-beta T cell physiology J:224849
abnormal macrophage physiology J:224849
abnormal microglial cell physiology J:224849
decreased effector memory CD4-positive, alpha-beta T cell number J:224849
decreased interferon-gamma secretion J:224849
decreased leukocyte cell number J:224849
decreased macrophage cell number J:224849
decreased monocyte cell number J:224849
decreased neutrophil cell number J:224849
increased susceptibility to Coronaviridae infection J:224849
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:224849
Myd88tm1.1Medz/Myd88tm1.1Medz
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:209373
Myd88tm1.1Medz/Myd88tm1.1Medz
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:209373
abnormal memory T cell physiology J:209373
abnormal T-helper 1 physiology J:209373
abnormal T-helper 17 cell physiology J:209373
Myd88tm1Aki/Myd88tm1Aki
(Not Specified)
abnormal cytokine secretion J:89257, J:88906
abnormal dendritic cell physiology J:96773
abnormal macrophage physiology J:96773
abnormal NK cell physiology J:88906
abnormal NK T cell physiology J:88906
abnormal T cell physiology J:96773
decreased B cell proliferation J:96773
increased susceptibility to Herpesvirales infection J:88906
Myd88tm1Aki/Myd88tm1Aki
(B6.129P2-Myd88tm1Aki)
abnormal chemokine secretion J:102879
abnormal cytokine secretion J:116670, J:162707
abnormal dendritic cell differentiation J:139001
abnormal dendritic cell physiology J:116670, J:118954
abnormal immune system physiology J:121070
abnormal innate immunity J:162707
abnormal macrophage physiology J:116670
abnormal NK cell physiology J:139001
abnormal response to infection J:121070
abnormal T cell physiology J:97662
bronchiolitis J:162707
decreased inflammatory response J:123946
decreased interferon-alpha secretion J:97662
decreased interferon-gamma secretion J:116763, J:118954
decreased interleukin-6 secretion J:118954, J:121070
decreased interleukin-12 secretion J:116670
decreased interleukin-12b secretion J:116763, J:118954
decreased susceptibility to parasitic infection J:116763
decreased tumor necrosis factor secretion J:116670, J:116763, J:121070
increased dendritic cell number J:116763
increased susceptibility to Coronaviridae infection J:162707
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:162707
increased susceptibility to Picornaviridae infection J:97662
Myd88tm1Aki/Myd88tm1Aki
(involves: 129P2/OlaHsd)
abnormal cytokine level J:174941
abnormal cytokine secretion J:167340
abnormal dendritic cell physiology J:174941, J:137522
abnormal interferon level J:137522
abnormal macrophage physiology J:174941
abnormal neutrophil physiology J:145345
abnormal tumor necrosis factor level J:103464, J:124334
decreased circulating tumor necrosis factor level J:139030
decreased interferon-alpha secretion J:144400
decreased interferon-gamma secretion J:210086
decreased interleukin-6 secretion J:167340
decreased susceptibility to experimental autoimmune encephalomyelitis J:105435
increased IgA level J:210086
increased IgE level J:115059
increased IgG1 level J:115059
increased susceptibility to bacterial infection J:210086
increased susceptibility to induced colitis J:167340
increased susceptibility to Picornaviridae infection J:137522
Myd88tm1Aki/Myd88tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal chemokine secretion J:141143
abnormal cytokine secretion J:117688
abnormal dendritic cell physiology J:122394
abnormal macrophage physiology J:141143, J:117688
decreased IgG2b level J:137066
decreased IgG3 level J:137066
decreased IgG level J:137066
decreased interleukin-1 beta secretion J:124226
decreased interleukin-6 secretion J:147023
immune system phenotype J:132662
Myd88tm1Aki/Myd88tm1Aki
(C.129P2-Myd88tm1Aki)
decreased susceptibility to induced arthritis J:178054
Myd88tm1Aki/Myd88tm1Aki
(B6.129-Myd88tm1Aki)
abnormal susceptibility to bacterial infection J:189854
decreased interleukin-6 secretion J:189854
decreased tumor necrosis factor secretion J:189854
Myd88tm1Aki/Myd88tm1Aki
Sh3bp2tm1.1Ics/Sh3bp2tm1.1Ics

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:221901
Myd88tm1Aki/Myd88tm1Aki
Tanktm1Aki/Tanktm1Aki

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
increased anti-double stranded DNA antibody level J:151757
Myd88tm1Aki/Myd88tm1Aki
Tg(IghelMD4)4Ccg/0
Tg(KLK4mHEL)6Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased mature B cell number J:115059
increased B-1 B cell number J:115059
Myd88tm1Aki/Myd88tm1Aki
Ticam1tm1Aki/Ticam1+

(B6.129P2-Myd88tm1Aki Ticam1tm1Aki)
decreased macrophage cytokine production J:140485
decreased macrophage nitric oxide production J:140485
increased susceptibility to parasitic infection J:140485
increased susceptibility to parasitic infection induced morbidity/mortality J:140485
Myd88tm1Aki/Myd88tm1Aki
Ticam1tm1Aki/Ticam1tm1Aki

(involves: 129P2/OlaHsd)
abnormal dendritic cell physiology J:174941
abnormal macrophage physiology J:174941
Myd88tm1Aki/Myd88tm1Aki
Ticam1tm1Aki/Ticam1tm1Aki

(B6.129P2-Myd88tm1Aki Ticam1tm1Aki)
decreased macrophage cytokine production J:140485
decreased macrophage nitric oxide production J:140485
increased susceptibility to parasitic infection J:140485
increased susceptibility to parasitic infection induced morbidity/mortality J:140485
Myd88tm1Aki/Myd88tm1Aki
Tnfaip3tm1.1Gvl/Tnfaip3tm1.1Gvl
Tg(Vil1-cre)997Gum/0

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
increased susceptibility to induced colitis J:163410
Myd88tm1Aki/Myd88tm1Aki
Tnip1tm1.1Pcoh/Tnip1tm1.1Pcoh

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:176826
Myd88tm1Aki/Myd88tm1Aki
Traddtm1.1Mpa/Traddtm1.1Mpa

(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
decreased circulating tumor necrosis factor level J:139030
Myd88tm1Defr/Myd88tm1Defr
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal NK cell physiology J:139001
Myd88tm1Defr/Myd88tm1Defr
Tg(Itgax-cre)1-1Reiz/0

(B6.Cg-Myd88tm1Defr Tg(Itgax-cre)1-1Reiz)
abnormal dendritic cell antigen presentation J:139001
abnormal dendritic cell differentiation J:139001
abnormal dendritic cell physiology J:139001
abnormal NK cell physiology J:139001
abnormal T-helper 1 cell differentiation J:139001
decreased circulating interleukin-6 level J:139001
decreased circulating interleukin-12b level J:139001
decreased IgG1 level J:139001
decreased IgG2b level J:139001
decreased IgG2c level J:139001
Myd88tm1Defr/Myd88tm1Defr
Tnip1tm1.2Ama/Tnip1tm1.2Ama
Tg(Itgax-cre)1-1Reiz/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA)
immune system phenotype J:205446
Myd88tm1Hlz/Myd88tm1Hlz
(B6.129P2-Myd88tm1Hlz)
abnormal chemokine level J:188968
decreased circulating interleukin-6 level J:188968
decreased circulating interleukin-10 level J:188968
decreased circulating interleukin-12b level J:188968
decreased interleukin-6 secretion J:188968
decreased interleukin-10 secretion J:188968
decreased neutrophil cell number J:188968
decreased tumor necrosis factor secretion J:188968
Myd88tm1Hlz/Myd88tm1Hlz
Lyz2tm1(cre)Ifo/Lyz2+

(B6.129P2-Myd88tm1Hlz Lyz2tm1(cre)Ifo)
abnormal circulating chemokine level J:188968
decreased CXCL10 level J:188968
immune system phenotype J:188968
increased circulating tumor necrosis factor level J:188968
Mydgftm1Kcw/Mydgftm1Kcw
(BALB/c-Mydgftm1Kcw)
decreased inflammatory response J:216795
Myh1tm1b(KOMP)Wtsi/Myh1tm1b(KOMP)Wtsi
(C57BL/6N-Myh1tm1b(KOMP)Wtsi/J)
decreased leukocyte cell number J:211773
Myh4arl/Myh4arl
(involves: C3H/HeH * C57BL/6J)
myositis J:181892
Myh6tm1Jse/Myh6+
Tg(Myh6-TNNI3*G203S)1Chs/0

(involves: 129X1/SvJ * C57BL/6)
liver inflammation J:153302
lung inflammation J:153302
Myh9tm1.1(MYH9*)Mjk/Myh9+
(B6.Cg-Myh9tm1.1(MYH9*)Mjk)
abnormal neutrophil morphology J:175367
increased incidence of corneal inflammation J:175367
Myh9tm1.1(MYH9*)Mjk/Myh9tm1.1(MYH9*)Mjk
(B6.129-Myh9tm1.1(MYH9*)Mjk)
abnormal neutrophil morphology J:175367
Myh9tm1.1Dash/Myh9+
(involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA)
abnormal thrombopoiesis J:204923
Myh9tm5Rsad/Myh9tm5Rsad
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal leukocyte migration J:164684
abnormal T cell physiology J:164684
Myh9tm5Rsad/Myh9tm5Rsad
Tg(Lck-cre)#Nik/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2)
abnormal CD8-positive, alpha-beta T cell physiology J:164684
abnormal leukocyte adhesion J:164684
abnormal leukocyte migration J:164684
abnormal lymph node cell ratio J:164684
abnormal T cell physiology J:164684
decreased CD8-positive, alpha-beta T cell number J:164684
Myh9tm6.1(EGFP/MYH9*)Rsad/Myh9+
(involves: 129S4/SvJae * BALB/cJ * C57BL/6)
abnormal neutrophil morphology J:175367
Myh9tm7.1Rsad/Myh9+
(involves: BALB/cJ)
abnormal neutrophil morphology J:175367
Myh9tm7.1Rsad/Myh9tm7.1Rsad
(involves: BALB/cJ)
abnormal neutrophil morphology J:175367
Myh10tm7Rsad/Myh10tm7Rsad
Tg(Myh6-cre)2182Mds/0

(involves: 129S6/SvEvTac * C57BL/6J * FVB/N)
heart inflammation J:170148
Myl3tm1a(EUCOMM)Hmgu/Myl3tm1a(EUCOMM)Hmgu
Tg(Col2a1-cre)1Xya/0

(involves: C57BL/6J * C57BL/6N)
osteoarthritis J:343166
Myl3tm1a(EUCOMM)Hmgu/Myl3tm1a(EUCOMM)Hmgu
Tg(Col2a1-cre/ERT)KA3Smac/0

(involves: C57BL/6J * C57BL/6N * FVB/N)
increased susceptibility to induced arthritis J:343166
Mylktm1Mzhu/Mylktm1Mzhu
Taglntm1(cre/ERT2)Feil/?

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6)
small intestinal inflammation J:141907
Myo1dem1Btlr/Myo1dem1Btlr
(C57BL/6J-Myo1dem1Btlr)
increased susceptibility to colitis induced morbidity/mortality J:267525
increased susceptibility to induced colitis J:267525
Myo1dm1Btlr/Myo1dm1Btlr
(C57BL/6J-Myo1dm1Btlr)
increased susceptibility to induced colitis J:267525
Myo1dm1Btlr/Myo1dm2Btlr
(C57BL/6J-Myo1dm1Btlr/Myo1dm2Btlr)
increased susceptibility to induced colitis J:267525
Myo1dm2Btlr/Myo1dm2Btlr
(C57BL/6J-Myo1dm2Btlr)
increased susceptibility to induced colitis J:267525
Myo1dm3Btlr/Myo1dm3Btlr
(C57BL/6J-Myo1dm3Btlr)
increased susceptibility to induced colitis J:267525
Myo1dm4Btlr/Myo1dm4Btlr
(C57BL/6J-Myo1dm4Btlr)
increased susceptibility to induced colitis J:267525
Myo1ftm1.1Flv/Myo1ftm1.1Flv
(involves: 129S6/SvEvTac)
impaired neutrophil chemotaxis J:113020
Myo1gtm1.2Mfk/Myo1gtm1.2Mfk
(Not Specified)
abnormal B cell physiology J:209304
decreased B cell number J:209304
decreased tumor necrosis factor secretion J:209304
immune system phenotype J:209304
increased B cell number J:209304
Myo1gtm1.2Mfk/Myo1gtm1.2Mfk
(involves: C57BL/6 * FVB/N * SJL)
abnormal T cell physiology J:212451
Myo1gtm1.2Mfk/Myo1gtm1.2Mfk
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6 * FVB/N * SJL)
abnormal T cell physiology J:212451
Myo3btm1b(EUCOMM)Hmgu/Myo3btm1b(EUCOMM)Hmgu
(C57BL/6N-Myo3btm1b(EUCOMM)Hmgu/J)
decreased leukocyte cell number J:211773
Myo5ad-2Btlr/Myo5ad-2Btlr
(C57BL/6J-Myo5ad-2Btlr)
immune system phenotype J:133118
Myo5ad-Btlr/Myo5ad-Btlr
(C57BL/6J-Myo5ad-Btlr)
immune system phenotype J:133117
Myo5ad-l20J/Myo5ad-l20J
(involves: C57BL/6J)
immune system phenotype J:111253
Myo6em1(IMPC)Tcp/Myo6em1(IMPC)Tcp
(C57BL/6N-Myo6em1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
Myo9atm1b(EUCOMM)Wtsi/Myo9atm1b(EUCOMM)Wtsi
(C57BL/6N-Myo9atm1b(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Myo9btm1.2Bah/Myo9btm1.2Bah
(B6.Cg-Myo9btm1.2Bah)
abnormal macrophage physiology J:162326
decreased leukocyte cell number J:162326
impaired macrophage chemotaxis J:162326
Myo18atm1c(KOMP)Wtsi/Myo18atm1c(KOMP)Wtsi
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N)
immune system phenotype J:277320
Myoz1tm1b(EUCOMM)Hmgu/Myoz1tm1b(EUCOMM)Hmgu
(C57BL/6N-Myoz1tm1b(EUCOMM)Hmgu/Ieg)
increased marginal zone B cell number J:211773
Mypnem1(IMPC)J/Mypnem1(IMPC)J
(C57BL/6NJ-Mypnem1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
mypy/mypy
(C57BL/6J-mypy)
abnormal macrophage physiology J:105543
increased susceptibility to Herpesvirales infection J:105543
increased susceptibility to Riboviria infection J:105543
Mysm1tm1a(KOMP)Wtsi/Mysm1tm1a(KOMP)Wtsi
(Not Specified)
decreased B cell number J:165965
decreased leukocyte cell number J:165965
decreased mature B cell number J:165965
increased granulocyte number J:165965
increased IgG2b level J:165965
increased T cell number J:165965
Mysm1tm1b(KOMP)Wtsi/Mysm1tm1b(KOMP)Wtsi
Tg(MMTV-cre)4Mam/0

(involves: 129 * C57BL/6N * FVB/N)
abnormal T cell differentiation J:179287
arrested B cell differentiation J:179287
decreased B cell number J:179287
decreased immature B cell number J:179287
decreased pre-B cell number J:179287
decreased pro-B cell number J:179287
Mzb1tm1.2Rug/Mzb1tm1.2Rug
(involves: 129S2/SvPas * BALB/cJ * C57BL/6 * SJL)
decreased pre-B cell number J:211639
immune system phenotype J:211639
impaired humoral immune response J:211639
increased pro-B cell number J:211639
Mzf1tm1Ppp/Mzf1tm1Ppp
(involves: 129)
abnormal bone marrow development J:70407
abnormal myelopoiesis J:70407
N4bp1em1Vmd/N4bp1em1Vmd
(C57BL/6N-N4bp1em1Vmd)
decreased interleukin-6 secretion J:297419
immune system phenotype J:297419
N4bp1tm1.2Vmd/N4bp1tm1.2Vmd
(involves: C57BL/6)
abnormal macrophage physiology J:297419
decreased susceptibility to bacterial infection induced morbidity/mortality J:297419
increased activated T cell number J:297419
increased circulating interleukin-6 level J:297419
increased circulating tumor necrosis factor level J:297419
increased germinal center B cell number J:297419
increased interleukin-6 secretion J:297419
increased Ly6C high monocyte number J:297419
increased tumor necrosis factor secretion J:297419
lung inflammation J:297419
Naa10em1(IMPC)Mbp/Y
(C57BL/6NCrl-Naa10em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
small spleen J:211773
Naa10em1(IMPC)Mbp/Naa10em1(IMPC)Mbp
(C57BL/6NCrl-Naa10em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Naa16em1(IMPC)J/Naa16em1(IMPC)J
(C57BL/6NJ-Naa16em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Naa25em1(IMPC)Tcp/Naa25+
(C57BL/6NCrl-Naa25em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged thymus J:211773
Naa35em1(IMPC)J/Naa35+
(C57BL/6NJ-Naa35em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Naa38em1(IMPC)Ccpcz/Naa38+
(C57BL/6N-Naa38em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Naa50em1(IMPC)Mbp/Naa50+
(C57BL/6N-Naa50em1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Nabp2tm1.1Kkha/Nabp2tm1.1Kkha
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:195140
Nabp2tm1.1Kkha/Nabp2tm1.1Kkha
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NTac)
increased thymocyte apoptosis J:195140
Nabp2tm1.1Nfel/Nabp2tm1.2Nfel
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL)
immune system phenotype J:190019
Nabp2tm1Schg/Nabp2tm1Schg
(involves: 129S7/SvEvBrd * C57BL/6)
increased spleen red pulp amount J:228558
nad/nad
(C(D2)-nad)
abnormal bronchus-associated lymphoid tissue morphology J:156089
Nadsyn1tm1b(KOMP)Wtsi/Nadsyn1tm1b(KOMP)Wtsi
(C57BL/6N-Nadsyn1tm1b(KOMP)Wtsi/Ucd)
enlarged spleen J:211773
Nagktm1b(EUCOMM)Hmgu/Nagktm1b(EUCOMM)Hmgu
(C57BL/6N-Nagktm1b(EUCOMM)Hmgu/H)
increased neutrophil cell number J:211773
Naglutm1Efn/Naglutm1Efn
(either: (involves: 129S/SvEv * C57BL/6) or (involves: C57BL/6))
abnormal Kupffer cell morphology J:58950
abnormal macrophage morphology J:58950
Naglutm1Efn/Naglutm1Efn
(involves: 129S/SvEv * C57BL/6J)
increased susceptibility to otitis media J:129390
Naip5Lgn1-s/Naip5Lgn1-s
(A/J)
increased susceptibility to bacterial infection J:20633
Naip5m1Btlr/Naip5m1Btlr
(C57BL/6J-Naip5m1Btlr)
decreased interleukin-1 beta secretion J:234250
Naip5m2Btlr/Naip5+
(C57BL/6J-Naip5m2Btlr)
decreased interleukin-1 beta secretion J:234248
Naip5m2Btlr/Naip5m2Btlr
(C57BL/6J-Naip5m2Btlr)
decreased interleukin-1 beta secretion J:234248
Naip5tm1Vnce/Naip5tm1Vnce
(C57BL/6-Naip5tm1Vnce)
decreased interleukin-1 beta secretion J:141008
Naipctm1.1Kmma/Naipctm1.1Kmma
(involves: BALB/cJ * C57BL/6)
decreased interleukin-1 beta secretion J:222114
decreased susceptibility to induced colitis J:222114
Naipctm1Kmma/Naipctm1Kmma
Lyz2tm1(cre)Ifo/Lyz2+

(B6.Cg-Lyz2tm1(cre)Ifo Naipctm1Kmma)
decreased susceptibility to induced colitis J:222114
Naipctm1Kmma/Naipctm1Kmma
Tg(Vil1-cre)997Gum/0

(B6.Cg-Naipctm1Kmma Tg(Vil1-cre)997Gum)
decreased susceptibility to induced colitis J:222114
Nalcnem1(IMPC)Mbp/Nalcn+
(C57BL/6N-Nalcnem1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
NamptGt(RRR084)Byg/Nampt+
(involves: 129P2/OlaHsd * C57BL/6)
decreased interleukin-6 secretion J:194883
decreased neutrophil cell number J:194883
Nampttm1Oleo/Nampttm1Oleo
Tg(CD2-icre)4Kio/0

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/10 * CBA/Ca)
decreased B cell number J:141448
decreased double-negative T cell number J:141448
decreased T cell number J:141448
thymus hypoplasia J:141448
Nat8f2tm1.1(KOMP)Vlcg/Nat8f2tm1.1(KOMP)Vlcg
(C57BL/6N-Nat8f2tm1.1(KOMP)Vlcg/J)
enlarged lymph nodes J:211773
Nav1em1(IMPC)Mbp/Nav1em1(IMPC)Mbp
(C57BL/6N-Nav1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Nav2em1(IMPC)Tcp/Nav2em1(IMPC)Tcp
(C57BL/6NCrl-Nav2em1(IMPC)Tcp/Tcp)
increased neutrophil cell number J:211773
Nba4NZB/Nba4NZB
(involves: NZB * SWR)
glomerulonephritis J:96060
increased anti-double stranded DNA antibody level J:96060
increased anti-histone antibody level J:96263
increased anti-single stranded DNA antibody level J:96060
increased IgG3 level J:96263
Nba4NZB/Nba4SWR
(involves: NZB * SWR)
increased anti-histone antibody level J:96263
increased IgG3 level J:96263
Nba5NZB/Nba5NZB
(C57BL/6-Nba5 Yaa)
glomerulonephritis J:95829
increased susceptibility to type III hypersensitivity reaction J:95829
Nba8NZB/Nba8NZB
(involves: NZB * SWR)
glomerulonephritis J:73097
Nba10NZB/?
(involves: C57BL/6 * NZB * SB/Le)
glomerulonephritis J:95829
increased anti-chromatin antibody level J:95829
increased anti-double stranded DNA antibody level J:95829
increased susceptibility to type III hypersensitivity reaction J:95829
Nba10NZB/Nba10NZB
Tg(Tnfsf13b)1Fma/0

(involves: C57BL/6 * DBA/2J * NZB)
glomerulonephritis J:134128
increased anti-chromatin antibody level J:134128
increased anti-double stranded DNA antibody level J:134128
increased B cell number J:134128
increased IgG level J:134128
increased IgM level J:134128
increased marginal zone B cell number J:134128
increased susceptibility to systemic lupus erythematosus J:134128
Nba10NZB/Nba10NZB
Tlr7tm1Aki/Y
X/Yaa

(B6.Cg-Nba10NZB Tlr7tm1Aki Yaa)
abnormal immune serum protein physiology J:137656
glomerulonephritis J:137656
increased anti-chromatin antibody level J:137656
increased monocyte cell number J:137656
Nba10NZB/Nba10NZB
X/Yaa

(C57BL/6-Nba2 Yaa)
abnormal immune serum protein physiology J:137656
glomerulonephritis J:95829, J:137656
increased anti-chromatin antibody level J:137656
increased anti-nuclear antigen antibody level J:95829
increased autoantibody level J:137656
increased monocyte cell number J:137656, J:129409
increased susceptibility to autoimmune disorder J:95829
increased susceptibility to type III hypersensitivity reaction J:95829
Nba11NZB/Nba11NZB
(involves: NZB * SWR)
glomerulonephritis J:96263
Nba11NZB/Nba11SWR
(involves: NZB * SWR)
glomerulonephritis J:96263
Nba12NZB/Nba12NZB
(involves: NZB * SWR)
increased anti-double stranded DNA antibody level J:96263
Nba12NZB/Nba12SWR
(involves: NZB * SWR)
increased anti-double stranded DNA antibody level J:96263
Nbeal2gps/Nbeal2gps
(129S1/SvImJ-Nbeal2gps)
decreased neutrophil cell number J:236370
Nbeal2tm1a(EUCOMM)Wtsi/Nbeal2tm1a(EUCOMM)Wtsi
(C57BL/6N-Nbeal2tm1a(EUCOMM)Wtsi/Wtsi)
enlarged spleen J:220801
increased inflammatory response J:220801
increased leukocyte cell number J:211773
Nbeal2tm1Lex/Nbeal2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
enlarged spleen J:201413
Nbnem7Jpt/Nbntm2Zqw
Tg(VAV1-cre)1Graf/0

(involves: 129P2/OlaHsd)
abnormal T cell morphology J:277750
absent mature B cells J:277750
decreased B cell number J:277750
decreased leukocyte cell number J:277750
decreased T cell number J:277750
decreased thymocyte number J:277750
increased CD8-positive, alpha-beta T cell number J:277750
increased pro-B cell number J:277750
Nbntm1Jpt/Nbntm1Jpt
(involves: 129S7/SvEvBrd)
immune system phenotype J:75956
Nbntm1Nus/Nbntm2Nus
Tg(CD19-cre/ERT2)1Cgn/0

(Not Specified)
abnormal B cell physiology J:96102
decreased B cell proliferation J:96102
decreased IgG1 level J:96102
decreased IgG2a level J:96102
decreased IgG2b level J:96102
decreased IgG3 level J:96102
decreased IgG level J:96102
Nbntm1Xu/Nbntm1Xu
(Not Specified)
abnormal cell-mediated immunity J:75272
decreased CD4-positive, alpha-beta T cell number J:75272
decreased mature B cell number J:75272
decreased pre-B cell number J:75272
decreased T cell number J:75272
thymus hypoplasia J:75272
Nbntm2Zqw/Nbntm2Zqw
Tg(VAV1-cre)1Graf/0

(involves: 129P2/OlaHsd)
abnormal bone marrow development J:251434
decreased leukocyte cell number J:251434
Nbr1tm1.1Jmos/Nbr1tm1.1Jmos
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129X1/SvJ * C57BL/6J)
abnormal T-helper 1 cell differentiation J:165438
abnormal T-helper 2 cell differentiation J:165438
decreased inflammatory response J:165438
decreased interferon-gamma secretion J:165438
decreased interleukin-4 secretion J:165438
decreased interleukin-5 secretion J:165438
decreased interleukin-13 secretion J:165438
Nbr1tm1Whca/Nbr1tm1Whca
(B6.129P2-Nbr1tm1Whca)
abnormal osteoclast physiology J:162412
Nbwa1NZB/?
(involves: BALB/c * NZB * NZW)
increased anti-chromatin antibody level J:88464
increased anti-double stranded DNA antibody level J:88464
increased anti-single stranded DNA antibody level J:88464
increased susceptibility to systemic lupus erythematosus J:88464
Nbwa2NZB/?
(involves: BALB/c * NZB * NZW)
glomerulonephritis J:88464
increased IgG level J:88464
increased IgM level J:88464
increased susceptibility to systemic lupus erythematosus J:88464
Nbwa2NZW/?
(involves: BALB/c * NZB * NZW)
increased anti-double stranded DNA antibody level J:88464
increased susceptibility to systemic lupus erythematosus J:88464
Ncam2tm1b(EUCOMM)Hmgu/Ncam2tm1b(EUCOMM)Hmgu
(C57BL/6N-Ncam2tm1b(EUCOMM)Hmgu/Orl)
increased eosinophil cell number J:211773
Ncapd2em1Cya/Ncapd2+
(C57BL/6N-Ncapd2em1Cya)
decreased susceptibility to induced colitis J:310248
Ncaph2nes/Ncaph2nes
(C57BL/6JSfdAnu-Ncaph2nes/Anu)
abnormal double-negative T cell morphology J:123300
abnormal splenic cell ratio J:123300
abnormal T cell morphology J:123300
abnormal thymus cell ratio J:123300
abnormal thymus cortex morphology J:123300
abnormal thymus corticomedullary boundary morphology J:123300
decreased CD8-positive, alpha-beta T cell number J:123300
decreased double-negative T cell number J:123300
decreased double-positive T cell number J:123300
decreased T cell number J:123300
decreased thymocyte number J:123300
thymus hypoplasia J:123300
Ncaph2nes/Ncaph2nes
Tg(TcrHEL3A9)1Mmd/0

(C57BL/6-Ncaph2nes Tg(TcrHEL3A9)1Mmd)
abnormal double-negative T cell morphology J:123300
abnormal thymus cell ratio J:123300
decreased double-positive T cell number J:123300
Nceh1tm1Ishi/Nceh1tm1Ishi
(B6.129S7-Nceh1tm1Ishi)
abnormal macrophage physiology J:152385
Ncf1em1(IMPC)Mbp/Ncf1em1(IMPC)Mbp
(C57BL/6N-Ncf1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Ncf1em1Nansh/Ncf1em1Nansh
(involves: C57BL/6J)
immune system phenotype J:329553
Ncf1m1J/Ncf1m1J
(B6.Cg-Dock7m +/+ Leprdb/J)
abnormal macrophage physiology J:83428
decreased susceptibility to Orthomyxoviridae infection J:145306
impaired granulocyte bactericidal activity J:83428
Ncf1tm1Hbd/Ncf1tm1Hbd
(involves: 129)
abnormal neutrophil physiology J:77597, J:74593
granulomatous inflammation J:74593
Ncf1tm1Hbd/Ncf1tm1Hbd
(involves: C57BL/6)
immune system phenotype J:118561
Ncf1tm1Shl/Ncf1tm1Shl
(involves: 129S2/SvPas * C57BL/6J)
abnormal response to infection J:28267
increased acute inflammation J:28267
increased susceptibility to infection J:28267
Ncf1tm1Shl/Ncf1tm1Shl
(B6.129S2-Ncf1tm1Shl)
abnormal inflammatory response J:142617
granulomatous inflammation J:111142
Ncf2tm1a(EUCOMM)Wtsi/Ncf2tm1a(EUCOMM)Wtsi
(C57BL/6N-Ncf2tm1a(EUCOMM)Wtsi/Wtsi)
decreased alpha-beta T cell number J:211773
decreased leukocyte cell number J:211773
decreased NK cell number J:211773
decreased NK T cell number J:211773
decreased regulatory T cell number J:211773
decreased T cell number J:211773
increased KLRG1-positive NK cell number J:211773
Ncf2tm1b(EUCOMM)Wtsi/Ncf2+
(NZM2328.B6(Cg)-Ncf2tm1b(EUCOMM)Wtsi)
abnormal spleen germinal center morphology J:260777
increased activated T cell number J:260777
increased anti-double stranded DNA antibody level J:260777
increased B cell number J:260777
increased CD4-positive, alpha-beta memory T cell number J:260777
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:260777
increased CD8-positive, alpha-beta T cell number J:260777
increased follicular B cell number J:260777
increased germinal center B cell number J:260777
increased susceptibility to systemic lupus erythematosus J:260777
increased T cell number J:260777
Ncf2tm1b(EUCOMM)Wtsi/Ncf2tm1b(EUCOMM)Wtsi
(B6(Cg)-Ncf2tm1b(EUCOMM)Wtsi)
decreased CD8-positive, alpha-beta T cell number J:260777
increased susceptibility to fungal infection J:260777
lung inflammation J:260777
Ncf2tm1b(EUCOMM)Wtsi/Ncf2tm1b(EUCOMM)Wtsi
(NZM2328.B6(Cg)-Ncf2tm1b(EUCOMM)Wtsi)
abnormal spleen germinal center morphology J:260777
increased activated T cell number J:260777
increased anti-double stranded DNA antibody level J:260777
increased B cell number J:260777
increased follicular B cell number J:260777
increased germinal center B cell number J:260777
increased susceptibility to systemic lupus erythematosus J:260777
increased T cell number J:260777
Ncf4tm1Pth/Ncf4tm2Pth
(involves: 129P2/OlaHsd * C57BL/6)
abnormal neutrophil physiology J:119217
immune system phenotype J:119217
increased susceptibility to bacterial infection J:119217
Ncf4tm2Pth/Ncf4tm2Pth
(involves: 129P2/OlaHsd * C57BL/6)
abnormal neutrophil physiology J:121820
increased susceptibility to bacterial infection J:121820
Nckap1lm1Btlr/Nckap1lm1Btlr
(C57BL/6J-Nckap1lm1Btlr)
decreased alpha-beta T cell number J:272079
decreased B cell number J:272079
decreased CD4-positive, alpha-beta T cell number J:272079
decreased CD8-positive, alpha-beta T cell number J:272079
decreased CD8-positive, naive alpha-beta T cell number J:272079
decreased central memory CD8 positive, alpha-beta T cell number J:272079
decreased NK cell number J:272079
increased alpha-beta T cell number J:272079
increased CD8-positive, alpha-beta T cell number J:272079
increased effector memory CD4-positive, alpha-beta T cell number J:272079
increased effector memory CD8-positive, alpha-beta T cell number J:272079
Nckap1lm1Iri/Nckap1lm1Iri
(involves: C57BL/6)
abnormal CD4-positive T cell differentiation J:141377
abnormal immune system organ morphology J:141377
abnormal lymphopoiesis J:141377
abnormal regulatory T cell number J:141377
abnormal thymus lobule morphology J:141377
decreased CD4-positive, alpha-beta T cell number J:141377
decreased CD8-positive, alpha-beta T cell number J:141377
decreased double-positive T cell number J:141377
decreased lymphocyte cell number J:141377
decreased mature B cell number J:141377
decreased mature gamma-delta T cell number J:141377
decreased T cell proliferation J:141377
heart inflammation J:141377
impaired macrophage phagocytosis J:141377
impaired neutrophil chemotaxis J:141377
impaired neutrophil phagocytosis J:141377
increased circulating interleukin-6 level J:141377
increased circulating interleukin-17 level J:141377
increased double-negative T cell number J:141377
increased interleukin-6 secretion J:141377
increased interleukin-17 secretion J:141377
increased leukocyte cell number J:141377
increased neutrophil cell number J:141377
increased tumor necrosis factor secretion J:141377
liver inflammation J:141377
lung inflammation J:141377
lymph node hypoplasia J:141377
spleen hyperplasia J:141377
thymus hypoplasia J:141377
Ncoa1tm1Bwo/Ncoa1tm1Bwo
(involves: 129 * C57BL/6J)
immune system phenotype J:109522
Ncoa2em1(IMPC)Mbp/Ncoa2+
(C57BL/6N-Ncoa2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Ncoa2tm1.2Ipc/Ncoa2tm1.2Ipc
(involves: 129S2/SvPas * C57BL/6J)
immune system phenotype J:109522
Ncoa3tm1Jxu/Ncoa3tm1Jxu
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal B cell morphology J:109522
abnormal lymphopoiesis J:109522
abnormal spleen red pulp morphology J:109522
decreased splenocyte apoptosis J:109522
enlarged spleen J:109522
increased B cell number J:109522
increased B cell proliferation J:109522
increased CD4-positive, alpha-beta T cell number J:109522
increased CD8-positive, alpha-beta T cell number J:109522
increased leukocyte cell number J:109522
increased lymphocyte cell number J:109522
increased spleen germinal center size J:109522
increased T cell proliferation J:109522
Ncoa3tm1Jxu/Ncoa3tm1Jxu
(involves: 129S6/SvEvTac * C57BL/6)
decreased interleukin-1 beta secretion J:120086
increased circulating interleukin-1 beta level J:120086
increased circulating interleukin-6 level J:120086
increased circulating tumor necrosis factor level J:120086
increased interleukin-6 secretion J:120086
increased susceptibility to bacterial infection induced morbidity/mortality J:120086
increased susceptibility to endotoxin shock J:120086
increased tumor necrosis factor secretion J:120086
Ncoa5tm1.1(KOMP)Mbp/Ncoa5+
(C57BL/6N-Ncoa5tm1.1(KOMP)Mbp/Tcp)
increased eosinophil cell number J:211773
Ncoa5tm1Hxia/Ncoa5+
(involves: 129 * C57BL/6)
chronic liver inflammation J:207622
Ncor1tm1Rsd/Ncor1tm1Rsd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
arrested T cell differentiation J:65417
small thymus J:65417
Ncor2tm1Rev/Ncor2tm1Rev
(involves: 129/Sv * C57BL/6)
abnormal spleen morphology J:202976
enlarged spleen J:202976
increased osteoclast cell number J:202976
Ncr1m1J/Ncr1m1J
Pepcb/Pepcb
Ptprca/Ptprca

(B6.SJL-Ptprca Pepcb/BoyJ)
abnormal interferon level J:257226
abnormal NK cell physiology J:257226
abnormal susceptibility to infection induced morbidity/mortality J:257226
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:257226
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:257226
Ncr1noe/Ncr1noe
(involves: C57BL/6J)
abnormal NK cell physiology J:179728
decreased CD4-positive, alpha-beta T cell number J:179728
decreased CD8-positive, alpha-beta memory T cell number J:179728
decreased CD8-positive, alpha-beta T cell number J:179728
decreased susceptibility to Herpesvirales infection J:179728
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:179728
increased NK cell number J:179728
increased susceptibility to bacterial infection J:179728
Ncr1tm1.1(icre)Viv/Ncr1tm1.1(icre)Viv
(involves: C57BL/6)
abnormal NK cell physiology J:179728
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:179728
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:179728
Ncr1tm1Oman/Ncr1tm1Oman
(involves: 129S1/Sv * 129X1/SvJ)
decreased NK cell number J:112394
impaired natural killer cell mediated cytotoxicity J:112394
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:112394
Ncr1tm2.1Viv/Ncr1+
(involves: C57BL/6)
immune system phenotype J:186000
Ncstntm1.1Akli/Ncstntm1.1Akli
Tet2tm1.1Iaai/Tet2tm1.1Iaai
Tg(VAV1-cre)1Graf/0

(involves: 129S/SvEv * C57BL/6)
enlarged spleen J:196407
increased leukocyte cell number J:196407
myeloid hyperplasia J:196407
Ncstntm1.1Akli/Ncstntm1.1Akli
Tg(Mx1-cre)1Cgn/0

(involves: 129 * C57BL/6 * CBA * SJL)
abnormal spleen morphology J:172442
enlarged spleen J:172442
increased leukocyte cell number J:172442
increased monocyte cell number J:172442
increased spleen red pulp amount J:172442
Ncstntm1.1Akli/Ncstntm1.1Akli
Tg(VAV1-cre)1Graf/0

(involves: 129 * C57BL/6 * SJL)
abnormal spleen morphology J:172442
enlarged spleen J:172442
increased leukocyte cell number J:172442
increased monocyte cell number J:172442
increased spleen red pulp amount J:172442
Ncstntm1.1Akli/Ncstntm1.1Akli
Tg(VAV1-cre)1Graf/0

(involves: 129)
abnormal splenocyte physiology J:196407
enlarged spleen J:196407
Ndfip1Gt(RRD002)Byg/Ndfip1Gt(RRD002)Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell physiology J:116617
abnormal T-helper 2 physiology J:116617
dermatitis J:116617
increased activated T cell number J:116617
increased inflammatory response J:116617
increased spleen weight J:116617
increased T cell proliferation J:116617
lung inflammation J:116617
Ndfip1Gt(RRD002)Byg/Ndfip1Gt(RRD002)Byg
(involves: 129P2/OlaHsd)
abnormal T cell physiology J:205692
increased activated T cell number J:205692
increased interleukin-2 secretion J:205692
increased T cell proliferation J:205692
Ndfip1Gt(RRD002)Byg/Ndfip1Gt(RRD002)Byg
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraTcrb)425Cbn/0

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * BALB/c * C57BL/6)
immune system phenotype J:205692
Ndfip1kru/Ndfip1kru
(involves: C57BL/6JSfdAnu)
immune system phenotype J:188722
increased T-helper 2 cell number J:188722
Ndfip1tm1.1Pmo/Ndfip1tm1.1Pmo
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
esophageal inflammation J:205692
increased activated T cell number J:205692
increased eosinophil cell number J:205692
skin inflammation J:205692
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
Rnpc3tm1c(EUCOMM)Wtsi/Rnpc3tm1c(EUCOMM)Wtsi

(involves: 129S/SvEv * C57BL/6 * C57BL/6N)
decreased leukocyte cell number J:267519
decreased lymphocyte cell number J:267519
decreased monocyte cell number J:267519
decreased thymus weight J:267519
esophageal inflammation J:267519
small intestinal inflammation J:267519
thymus atrophy J:267519
thymus cortex atrophy J:267519
thymus medulla atrophy J:267519
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
Rragatm2Dmsa/Rragatm2Dmsa

(involves: 129S/SvEv * 129S4/SvJae * C57BL/6)
decreased B cell number J:213516
enlarged spleen J:213516
increased monocyte cell number J:213516
myeloid hyperplasia J:213516
Ndrg2tm1.1Hori/Ndrg2tm1.1Hori
(B6.129-Ndrg2tm1.1Hori)
abnormal microglial cell chemotaxis J:214686
decreased inflammatory response J:214686
decreased interleukin-6 secretion J:214686
Ndrg3em1(IMPC)Mbp/Ndrg3+
(C57BL/6NCrl-Ndrg3em1(IMPC)Mbp/Mmucd)
enlarged spleen J:211773
Ndst1b2b2230Clo/Ndst1b2b2230Clo
(C57BL/6J-Ndst1b2b2230Clo)
thymus hypoplasia J:175213
Ndst1tm1Je/Ndst1tm1Je
Tg(Tek-cre)1Ywa/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
abnormal leukocyte adhesion J:100456
abnormal leukocyte migration J:100456
decreased inflammatory response J:100456
impaired leukocyte tethering or rolling J:100456
Ndst2tm1Lkj/Ndst2tm1Lkj
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal mast cell morphology J:57121
decreased mast cell degranulation J:57121
decreased mast cell histamine storage J:57121
decreased mast cell number J:57121
decreased mast cell protease storage J:57121
Ndst2tm1Rls/Ndst2tm1Rls
(Not Specified)
abnormal response to infection J:57120
decreased mast cell degranulation J:57120
decreased mast cell histamine storage J:57120
decreased mast cell protease storage J:57120
Ndst2tm1Rls/Ndst2tm1Rls
(B6.Cg-Ndst2tm1Rls)
abnormal mast cell differentiation J:142880
decreased susceptibility to induced arthritis J:142880
Ndst3tm1.1Grob/Ndst3tm1.1Grob
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
decreased CD8-positive, alpha-beta T cell number J:138557
decreased lymphocyte cell number J:138557
Ndufs4tm1.1Rpa/Ndufs4tm1.1Rpa
(involves: 129S4/SvJaeSor)
microgliosis J:161393
Ndufs4tm1.1Rpa/Ndufs4tm1.1Rpa
(B6.129S4-Ndufs4tm1.1Rpa)
microgliosis J:190475
Ndufs4tm1Rpa/Ndufs4tm1Rpa
(B6.129S4-Ndufs4tm1Rpa)
microgliosis J:190475
Ndufs4tm1Rpa/Ndufs4tm1Rpa
Tg(Nes-cre)1Kln/0

(involves: 129S4/SvJaeSor * C57BL/6 * SJL)
microgliosis J:161393
Ndufs4tm1Rpa/Ndufs4tm1Rpa
Tg(Nes-cre)1Kln/0

(B6.Cg-Tg(Nes-cre)1Kln Ndufs4tm1Rpa)
microgliosis J:190475
Nedd4Gt(XA209)Byg/Nedd4Gt(XA209)Byg
(involves: 129P2/OlaHsd)
abnormal T cell activation J:143560
decreased B cell number J:143560
decreased IgG1 level J:143560
decreased IgG2b level J:143560
decreased IgG3 level J:143560
decreased interleukin-2 secretion J:143560
decreased T cell proliferation J:143560
increased CD4-positive, alpha-beta T cell number J:143560
increased CD8-positive, alpha-beta T cell number J:143560
increased IgM level J:143560
increased T cell number J:143560
Nedd4Gt(XB398)Byg/Nedd4Gt(XB398)Byg
(involves: 129P2/OlaHsd)
decreased B cell number J:143560
decreased IgG1 level J:143560
decreased IgG2b level J:143560
decreased IgG3 level J:143560
decreased interleukin-2 secretion J:143560
decreased T cell proliferation J:143560
increased CD4-positive, alpha-beta T cell number J:143560
increased CD8-positive, alpha-beta T cell number J:143560
increased IgM level J:143560
increased T cell number J:143560
Nedd4tm2b(EUCOMM)Hmgu/Nedd4+
(C57BL/6N-Nedd4tm2b(EUCOMM)Hmgu/H)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Nedd4ltm1.1Hkb/Nedd4ltm1.1Hkb
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL)
lung inflammation J:169296
Nedd4ltm1Shkr/Nedd4ltm1Shkr
(involves: C57BL/6 * C57BL/6J)
increased neutrophil cell number J:205657
lung inflammation J:205657
Nedd4ltm1Shkr/Nedd4ltm1Shkr
(involves: 129 * C57BL/6 * C57BL/6J)
lung inflammation J:205657
Nedd9m1Btlr/Nedd9m1Btlr
(C57BL/6J-Nedd9m1Btlr)
decreased B-1a cell number J:267702
decreased B-1b cell number J:267702
increased susceptibility to Herpesvirales infection J:267702
Nedd9tm1Miku/Nedd9tm1Miku
(B6.CBA-Nedd9tm1Miku)
abnormal B cell number J:116716
abnormal follicular B cell physiology J:116716
abnormal leukocyte migration J:116716
abnormal T cell physiology J:116716
decreased lymphocyte cell number J:116716
decreased marginal zone B cell number J:116716
increased follicular B cell number J:116716
lymph node hypoplasia J:116716
spleen hypoplasia J:116716
Neil1tm1Rsld/Neil1tm1Rsld
(involves: 129S1/Sv * C57BL/6)
joint inflammation J:106077
Neil2tm1.1Tkhz/Neil2tm1.1Tkhz
(involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl)
increased neutrophil cell number J:225791
lung inflammation J:225791
Neil3tm1Bjor/Neil3tm1Bjor
(involves: 129 * C57BL/6)
decreased microglial cell activation J:180177
Nek2em1(IMPC)Tcp/Nek2em1(IMPC)Tcp
(C57BL/6NCrl-Nek2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Nek7M1Btlr/Nek7+
(C57BL/6J-Nek7M1Btlr)
abnormal macrophage physiology J:226677
decreased inflammatory response J:226677
decreased interleukin-1 beta secretion J:226677
decreased interleukin-18 secretion J:226677
immune system phenotype J:226677
Nek7M1Btlr/Nek7M1Btlr
(C57BL/6J-Nek7M1Btlr)
abnormal macrophage physiology J:226677
decreased inflammatory response J:226677
decreased interleukin-1 beta secretion J:226677
decreased interleukin-18 secretion J:226677
decreased susceptibility to experimental autoimmune encephalomyelitis J:226677
immune system phenotype J:226677
Nek8m1Btlr/Nek8m1Btlr
(C57BL/6J-Nek8m1Btlr)
decreased CD8-positive, alpha-beta T cell number J:267544
decreased effector memory CD4-positive, alpha-beta T cell number J:267544
decreased effector memory CD8-positive, alpha-beta T cell number J:267544
increased CD4-positive, alpha-beta T cell number J:267544
increased susceptibility to induced colitis J:267544
Nek9tm1a(EUCOMM)Wtsi/Nek9+
(C57BL/6N-Nek9tm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Nelfaem1(IMPC)Tcp/Nelfa+
(C57BL/6NCrl-Nelfaem1(IMPC)Tcp/Tcp)
increased spleen weight J:211773
Nemp1em1(IMPC)Mbp/Nemp1em1(IMPC)Mbp
(C57BL/6NCrl-Nemp1em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Nemp2em1(IMPC)Tcp/Nemp2em1(IMPC)Tcp
(C57BL/6N-Nemp2em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Neu1a/Neu1a
(SM/J)
abnormal Kupffer cell morphology J:147881
Neu1tm1Adz/Neu1tm1Adz
(either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * NMRI))
abnormal Kupffer cell morphology J:76937
abnormal microglial cell morphology J:76937
enlarged spleen J:76937
spleen hyperplasia J:76937
Neurl2tm1.1(KOMP)Vlcg/Neurl2tm1.1(KOMP)Vlcg
(C57BL/6N-Neurl2tm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Neurl4em1(IMPC)Mbp/Neurl4em1(IMPC)Mbp
(C57BL/6NCrl-Neurl4em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
decreased leukocyte cell number J:211773
decreased neutrophil cell number J:211773
enlarged spleen J:211773
small spleen J:211773
Nexmifem1(IMPC)Tcp/Y
(C57BL/6N-Nexmifem1(IMPC)Tcp/Tcp)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased monocyte cell number J:211773
small spleen J:211773
Nexmifem1(IMPC)Tcp/Nexmif+
(C57BL/6N-Nexmifem1(IMPC)Tcp/Tcp)
increased neutrophil cell number J:211773
Nf1tm1.1Kest/Nf1tm1c(KOMP)Wtsi
Tg(Dhh-cre)1Mejr/0

(involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * C57BL/6NTac * FVB/N)
dermatitis J:234172
Nf1tm1c(KOMP)Wtsi/Nf1tm1c(KOMP)Wtsi
Tg(Dhh-cre)1Mejr/0

(involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * FVB/N)
dermatitis J:234172
Nf1tm1Fcr/Nf1+
Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Tg(Mx1-cre)1Cgn Nf1tm1Fcr Ptentm1Hwu)
abnormal spleen morphology J:232645
decreased B cell number J:232645
decreased lymphocyte cell number J:232645
decreased T cell number J:232645
enlarged spleen J:232645
increased granulocyte number J:232645
increased leukocyte cell number J:232645
increased macrophage cell number J:232645
increased monocyte cell number J:232645
increased spleen weight J:232645
Nf1tm1Fcr/Nf1tm1Fcr
(either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6J))
abnormal lymphatic vessel morphology J:18048
Nf1tm1Fcr/Nf1tm1Par
Tg(Tek-cre)1Ywa/0

(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
abnormal spleen morphology J:114455
absent spleen germinal center J:114455
enlarged spleen J:114455
spleen fibrosis J:114455
Nf1tm1Par/Nf1tm1Fcr
Tg(GFAP-cre)#Gtm/0

(involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal microglial cell morphology J:165209
Nf1tm1Par/Nf1tm1Par
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal myeloid leukocyte morphology J:90973
abnormal myelopoiesis J:90973
abnormal spleen morphology J:90973
enlarged spleen J:90973
increased granulocyte number J:90973
increased leukocyte cell number J:90973
increased lymphocyte cell number J:90973
increased monocyte cell number J:90973
increased neutrophil cell number J:90973
Nf1tm1Par/Nf1tm1Par
Tg(Prrx1-cre)1Cjt/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * SJL/J)
increased osteoclast cell number J:193350
Nf1tm1Tyj/Nf1+
(involves: 129S2/SvPas)
abnormal mast cell physiology J:142439
increased mast cell degranulation J:142439
Nf1tm1Tyj/Nf1+
Pak1tm1Cher/Pak1tm1Cher

(involves: 129S2/SvPas * C57BL/6)
abnormal mast cell physiology J:142439
Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+

(involves: 129S2/SvPas * C57BL/6)
spleen hyperplasia J:228258
Nf2tm1Gth/Nf2tm2Gth
Tg(Mpz-cre)2Brn/0

(involves: 129P2/OlaHsd * FVB/N)
increased susceptibility to otitis media J:63264
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)1Brn/0

(involves: 129P2/OlaHsd * FVB/N)
increased susceptibility to otitis media J:63264
Nf2tm2Gth/Nf2tm2Gth
Tg(Mpz-cre)2Brn/0

(involves: 129P2/OlaHsd * FVB/N)
increased susceptibility to otitis media J:63264
Nfam1em1(IMPC)Ccpcz/Nfam1em1(IMPC)Ccpcz
(C57BL/6N-Nfam1em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Nfat5tm1.1Itl/Nfat5tm1.1Itl
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NTac * FVB/N)
abnormal lymphatic vessel morphology J:201429
Nfat5tm1.1Joar/Nfat5tm1.1Joar
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal T cell physiology J:148271
Nfat5tm1Rao/Nfat5tm1Rao
(B6.129-Nfat5tm1Rao)
tubulointerstitial nephritis J:88636
Nfat5tm1Snh/Nfat5+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immunoglobulin level J:91482
decreased IgG level J:91482
decreased T cell proliferation J:91482
spleen hypoplasia J:91482
thymus hypoplasia J:91482
Nfatc1tm1Glm/Nfatc1tm2Glm
(chimera involves: 129S2/SvPas)
abnormal B cell physiology J:78376
abnormal immune system physiology J:78376
abnormal immunoglobulin level J:78376
abnormal interferon-gamma secretion J:78376
abnormal interleukin-2 secretion J:78376
abnormal lymphocyte cell number J:78376
abnormal lymphocyte physiology J:78376
abnormal T cell physiology J:78376
abnormal T-helper 2 physiology J:78376
decreased double-positive T cell number J:78376
decreased IgE level J:78376
decreased IgG1 level J:78376
decreased IgG2b level J:78376
decreased IgG3 level J:78376
decreased immunoglobulin level J:78376
decreased interleukin-4 secretion J:78376
decreased lymphocyte cell number J:78376
increased double-negative T cell number J:78376
increased IgA level J:78376
increased IgG2a level J:78376
increased IgM level J:78376
increased immunoglobulin level J:78376
Nfatc1tm1Rao/Nfatc1tm1Rao
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c)
abnormal B cell physiology J:177319
abnormal class switch recombination J:177319
abnormal marginal zone B cell physiology J:177319
decreased B cell number J:177319
decreased B cell proliferation J:177319
decreased B-1a cell number J:177319
decreased susceptibility to experimental autoimmune encephalomyelitis J:177319
increased B cell apoptosis J:177319
Nfatc1tm1Rao/Nfatc1tm1Rao
Nfatc2tm1Rao/Nfatc2tm1Rao
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c)
abnormal B cell physiology J:177319
decreased interleukin-2 secretion J:177319
Nfatc1tm1Rao/Nfatc1tm1Rao
Tg(Fcer2a-cre)5Mbu/0

(involves: C57BL/6 * CBA)
abnormal B cell physiology J:177319
abnormal class switch recombination J:177319
decreased B cell proliferation J:177319
decreased IgG2a level J:177319
decreased IgG3 level J:177319
decreased IgM level J:177319
decreased interleukin-2 secretion J:177319
increased IgM level J:177319
increased interleukin-10 secretion J:177319
Nfatc1tm3Glm/Nfatc1tm3Glm
Sh3bp2tm1Bjro/Sh3bp2tm1Bjro
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
abnormal osteoclast differentiation J:144598
decreased osteoclast cell number J:144598
liver inflammation J:144598
lung inflammation J:144598
lymph node inflammation J:144598
stomach inflammation J:144598
Nfatc1tm3Glm/Nfatc1tm3Glm
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal osteoclast differentiation J:144598
decreased osteoclast cell number J:144598
Nfatc2m1Anu/Nfatc2m1Anu
(C57BL/6NCrlAnu-Nfatc2m1Anu)
immune system phenotype J:104190
Nfatc2tm1Glm/Nfatc2tm1Glm
Nfatc3tm1c(EUCOMM)Hmgu/Nfatc3tm1c(EUCOMM)Hmgu
Tg(Itgax-cre)1-1Reiz/0

(involves: C57BL/6 * C57BL/6N * CBA)
decreased interleukin-2 secretion J:346703
Nfatc2tm1Glm/Nfatc2tm1Glm
Nfatc3tm1Glm/Nfatc3tm1Glm

(involves: 129S2/SvPas)
abnormal lymph node morphology J:51339
abnormal lymphocyte cell number J:51339
blepharitis J:51339
decreased T cell number J:51339
enlarged spleen J:51339
increased B cell number J:51339
increased inflammatory response J:51339
increased T cell number J:51339
interstitial pneumonia J:51339
Nfatc2tm1Rao/Nfatc2tm1Rao
(B6.Cg-Nfatc2tm1Rao)
abnormal mast cell physiology J:78089
decreased interleukin-4 secretion J:78089
decreased interleukin-13 secretion J:78089
decreased tumor necrosis factor secretion J:78089
Nfatc2tm1Rao/Nfatc2tm1Rao
Nfatc3tm1Grc/Nfatc3tm1Grc
Tg(Lck-cre)I57Jxm/0

(involves: ICR)
abnormal double-negative T cell morphology J:141917
abnormal T cell differentiation J:141917
increased T cell apoptosis J:141917
Nfatc2tm1Srf/Nfatc2tm1Srf
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell number J:110686
abnormal B cell physiology J:110686
abnormal lymph node B cell domain morphology J:110686
abnormal lymphocyte physiology J:110686
abnormal spleen germinal center morphology J:110686
abnormal T cell physiology J:110686
abnormal thymus involution J:110686
enlarged spleen J:110686
enlarged thymus J:110686
increased activated T cell number J:110686
thymus hyperplasia J:110686
Nfatc2tm1Srf/Nfatc2tm1Srf
(involves: 129P2/OlaHsd)
abnormal immune system organ morphology J:45252
abnormal immune system physiology J:45252
abnormal interleukin secretion J:45252
abnormal lymph node morphology J:45252
abnormal T cell physiology J:45252
enlarged lymph nodes J:45252
enlarged spleen J:45252
increased B cell number J:45252
increased lymphocyte cell number J:45252
increased T cell number J:45252
lymph node hyperplasia J:45252
Nfatc2tm1Srf/Nfatc2tm1Srf
(B6.Cg-Nfatc2tm1Srf)
abnormal CD4-positive, alpha-beta T cell physiology J:86279
abnormal T-helper 1 physiology J:86279
abnormal T-helper 2 physiology J:86279
decreased interferon-gamma secretion J:86279
increased IgE level J:86279
increased IgG1 level J:86279
increased immunoglobulin level J:86279
increased interleukin-4 secretion J:86279
increased interleukin-5 secretion J:86279
Nfatc2ipem1(IMPC)Ics/Nfatc2ipem1(IMPC)Ics
(C57BL/6N-Nfatc2ipem1(IMPC)Ics/Ics)
increased eosinophil cell number J:211773
Nfatc2iptm1.1Glm/Nfatc2iptm1.1Glm
(either: B6.129-Nfatc2iptm1.1Glm or C.129-Nfatc2iptm1.1Glm)
abnormal interleukin secretion J:157559
abnormal leukocyte morphology J:157559
abnormal T-helper 2 physiology J:157559
decreased circulating interleukin-4 level J:157559
decreased interferon-gamma secretion J:157559
decreased interleukin-3 secretion J:157559
decreased interleukin-4 secretion J:157559
decreased interleukin-5 secretion J:157559
decreased interleukin-13 secretion J:157559
decreased mast cell number J:157559
decreased T-helper 2 cell number J:157559
increased susceptibility to parasitic infection J:157559
Nfatc3tm1.1Grc/Nfatc3tm1.1Grc
(involves: C57BL/6)
immune system phenotype J:141917
lymph node hypoplasia J:141917
Nfatc3tm1Glm/Nfatc3tm1Glm
Tg(DO11.10)10Dlo/?

(involves: 129S2/SvPas * BALB/c * C3H * C57BL/6)
decreased double-positive T cell number J:50124
increased double-negative T cell number J:50124
small thymus J:50124
Nfatc3tm1Grc/Nfatc3tm1Grc
Tg(Lck-cre)I57Jxm/0

(involves: ICR)
abnormal T cell differentiation J:141917
decreased CD4-positive, alpha-beta T cell number J:141917
decreased CD8-positive, alpha-beta T cell number J:141917
decreased thymocyte number J:141917
increased double-negative T cell number J:141917
increased T cell apoptosis J:141917
lymph node hypoplasia J:141917
thymus hypoplasia J:141917
Nfe2tm1Sho/Nfe2+
(C.129S4-Nfe2tm1Sho)
enlarged spleen J:125982
increased susceptibility to Retroviridae infection J:125982
Nfe2tm1Sho/Nfe2tm1Sho
(involves: 129/Sv * 129S4/SvJae)
increased osteoclast cell number J:111270
Nfe2l1tm1Jefc/Nfe2l1tm1Ywk
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129X1/SvJ * C57BL/6J)
liver inflammation J:97188
Nfe2l2em1(IMPC)Ccpcz/Nfe2l2em1(IMPC)Ccpcz
(C57BL/6NCrl-Nfe2l2em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Nfe2l2tm1.1Sred/Nfe2l2tm1.1Sred
Tg(Scgb1a1-cre)1Grau/0

(involves: C57BL/6 * C57BL/6J)
decreased interleukin-1 beta secretion J:191916
decreased tumor necrosis factor secretion J:191916
Nfe2l2tm1Mym/Nfe2l2tm1Mym
(involves: 129P2/OlaHsd * ICR)
abnormal macrophage physiology J:118068
decreased CD4-positive, alpha-beta T cell number J:104016
decreased T cell number J:104016
enlarged lymph nodes J:104016
glomerulonephritis J:104016
increased anti-double stranded DNA antibody level J:104016
increased anti-nuclear antigen antibody level J:104016
increased IgG level J:104016
increased IgM level J:104016
increased spleen weight J:104016
lung inflammation J:118068
Nfe2l2tm1Mym/Nfe2l2tm1Mym
(involves: 129P2/OlaHsd * C57BL/6J)
increased susceptibility to induced colitis J:116676
Nfe2l2tm1Mym/Nfe2l2tm1Mym
(involves: 129P2/OlaHsd * CD-1)
increased acute inflammation J:122813
Nfe2l2tm1Mym/Nfe2l2tm1Mym
(involves: 129P2/OlaHsd * C57BL/6)
abnormal leukocyte adhesion J:150597
increased circulating interleukin-6 level J:136120
increased circulating tumor necrosis factor level J:136120
increased susceptibility to experimental autoimmune uveoretinitis J:150597
liver inflammation J:136120
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk
(involves: 129X1/SvJ)
abnormal spleen physiology J:91407
abnormal splenocyte physiology J:91407
decreased circulating interleukin-1 beta level J:100106
enlarged spleen J:91407
increased circulating interleukin-1 beta level J:100106
increased macrophage cell number J:100106
increased spleen weight J:91407
increased splenocyte apoptosis J:91407
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk
(B6.129X1-Nfe2l2tm1Ywk/J)
abnormal neutrophil physiology J:233699
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk
(B6.129X1-Nfe2l2tm1Ywk)
increased anti-double stranded DNA antibody level J:165602
Nfil3tm1.1(KOMP)Vlcg/Nfil3tm1.1(KOMP)Vlcg
(C57BL/6N-Nfil3tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
small thymus J:211773
Nfil3tm1.1Brad/Nfil3+
(B6.Cg-Nfil3tm1.1Brad)
decreased NK cell number J:152774
Nfil3tm1.1Brad/Nfil3tm1.1Brad
(B6.Cg-Nfil3tm1.1Brad)
abnormal NK cell differentiation J:152774
decreased interferon-gamma secretion J:152774
decreased NK cell number J:152774
immune system phenotype J:152774
impaired natural killer cell mediated cytotoxicity J:152774
increased memory T cell number J:152774
increased NK T cell number J:152774
Nfil3tm1.1Kubo/Nfil3tm1.1Kubo
(B6.Cg-Nfil3tm1.1Kubo)
abnormal interleukin secretion J:184570
decreased interleukin-9 secretion J:184570
decreased interleukin-10 secretion J:172134, J:184570
decreased interleukin-13 secretion J:172134, J:184570
decreased interleukin-17 secretion J:184570
increased susceptibility to experimental autoimmune encephalomyelitis J:172134
increased susceptibility to induced colitis J:172134
Nfil3tm1.2Kubo/Nfil3tm1.2Kubo
Tg(Itgax-cre)1-1Reiz/0

(involves: 129 * C57BL/6 * CBA)
immune system phenotype J:334296
Nfil3tm1Look/Nfil3tm1Look
(B6.129X1-Nfil3tm1Look)
abnormal NK cell differentiation J:155677
decreased interferon-gamma secretion J:155677
decreased NK cell number J:155677
impaired natural killer cell mediated cytotoxicity J:155677
Nfil3tm1Look/Nfil3tm1Look
(involves: 129X1/SvJ)
immune system phenotype J:209365
Nfil3tm1Pbro/Nfil3tm1Pbro
(involves: 129S6/SvEvTac * C57BL/6)
abnormal class switch recombination J:156521
decreased IgE level J:156521
decreased IgG1 level J:156521
decreased interleukin-4 secretion J:156521
immune system phenotype J:156521
Nfil3tm1Pbro/Nfil3tm1Pbro
(B6.129S6-Nfil3tm1Pbro)
abnormal circulating cytokine level J:209365
abnormal cytokine secretion J:209365
abnormal leukocyte morphology J:209365
abnormal plasma cell morphology J:209365
colitis J:209365
decreased NK cell number J:209365
increased circulating interferon-gamma level J:209365
increased circulating interleukin-10 level J:209365
increased circulating interleukin-12b level J:209365
increased circulating interleukin-17 level J:209365
increased circulating tumor necrosis factor level J:209365
increased interferon-gamma secretion J:209365
increased interleukin-10 secretion J:209365
increased interleukin-12b secretion J:209365
increased interleukin-17 secretion J:209365
increased macrophage cytokine production J:209365
increased T-helper 17 cell number J:209365
increased tumor necrosis factor secretion J:209365
Nfil3tm1Pbro/Nfil3tm1Pbro
Rag1tm1Mom/Rag1tm1Mom

(involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6)
immune system phenotype J:209365
Nfkb1M1Btlr/Nfkb1+
(C57BL/6J-Nfkb1M1Btlr)
decreased IgG level J:216054
impaired humoral immune response J:216054
Nfkb1M1Btlr/Nfkb1M1Btlr
(C57BL/6J-Nfkb1M1Btlr)
decreased IgG level J:216054
impaired humoral immune response J:216054
Nfkb1m2Btlr/Nfkb1+
(C57BL/6J-Nfkb1m2Btlr)
abnormal humoral immune response J:254822
decreased central memory CD4-positive, alpha-beta T cell number J:254822
decreased effector memory CD4-positive, alpha-beta T cell number J:254822
decreased IgM level J:254822
Nfkb1m2Btlr/Nfkb1m2Btlr
(C57BL/6J-Nfkb1m2Btlr)
abnormal humoral immune response J:254822
decreased CD8-positive, naive alpha-beta T cell number J:254822
decreased central memory CD4-positive, alpha-beta T cell number J:254822
decreased effector memory CD4-positive, alpha-beta T cell number J:254822
decreased IgE level J:254822
decreased IgG level J:254822
decreased IgM level J:254822
increased central memory CD8 positive, alpha-beta T cell number J:254822
Nfkb1M3Btlr/Nfkb1+
(C57BL/6J-Nfkb1M3Btlr)
abnormal humoral immune response J:254821
decreased IgE level J:254821
decreased IgG level J:254821
increased central memory CD8 positive, alpha-beta T cell number J:254821
Nfkb1M3Btlr/Nfkb1M3Btlr
(C57BL/6J-Nfkb1M3Btlr)
abnormal humoral immune response J:254821
decreased IgE level J:254821
decreased IgG level J:254821
increased central memory CD8 positive, alpha-beta T cell number J:254821
increased susceptibility to induced colitis J:254821
Nfkb1M4Btlr/Nfkb1M4Btlr
(C57BL/6J-Nfkb1M4Btlr)
decreased B-1 B cell number J:265169
Nfkb1M5Btlr/Nfkb1M5Btlr
(C57BL/6J-Nfkb1M5Btlr)
decreased B-1a cell number J:272117
decreased IgE level J:272117
decreased interleukin-1 beta secretion J:272117
Nfkb1M6Btlr/Nfkb1M6Btlr
(C57BL/6J-Nfkb1M6Btlr)
decreased IgE level J:272148
Nfkb1tm1a(KOMP)Wtsi/Nfkb1tm1a(KOMP)Wtsi
(B6JTyr;B6N-Nfkb1tm1a(KOMP)Wtsi/Wtsi)
increased leukocyte cell number J:175295, J:165965
Nfkb1tm1a(KOMP)Wtsi/Nfkb1tm1a(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
decreased IgA level J:213427
decreased IgG1 level J:213427
decreased NK cell number J:213427
decreased regulatory T cell number J:213427
increased leukocyte cell number J:213427
increased susceptibility to bacterial infection J:213427
lymphoid hyperplasia J:213427
Nfkb1tm1Bal/Nfkb1tm1Bal
(B6;129P-Nfkb1tm1Bal/J)
abnormal CD4-positive, alpha-beta T cell physiology J:118907
abnormal cytokine secretion J:79107
abnormal dendritic cell physiology J:118907
abnormal macrophage physiology J:118907
abnormal professional antigen presenting cell physiology J:118907
decreased susceptibility to autoimmune diabetes J:118907
immune system phenotype J:118907
Nfkb1tm1Bal/Nfkb1tm1Bal
(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:30268
abnormal humoral immune response J:37184
abnormal Peyer's patch follicle morphology J:77049
abnormal Peyer's patch germinal center morphology J:77049
abnormal Peyer's patch T cell area morphology J:77049
cecum inflammation J:67107
decreased B cell proliferation J:37184, J:30268
decreased IgA level J:37184
decreased IgE level J:37184
decreased IgG1 level J:37184
decreased IgM level J:30268
decreased immunoglobulin level J:37184
decreased interleukin-6 secretion J:37184
decreased myeloid dendritic cell number J:77049
decreased Peyer's patch number J:77049
decreased susceptibility to Picornaviridae infection induced morbidity/mortality J:37184
increased susceptibility to bacterial infection J:37184, J:67107
increased susceptibility to bacterial infection induced morbidity/mortality J:37184
large intestinal inflammation J:67107
peritoneal inflammation J:67107
small Peyer's patches J:77049
Nfkb1tm1Bal/Nfkb1tm1Bal
(involves: 129P2/OlaHsd)
decreased marginal zone B cell number J:65246
immune system phenotype J:113514
Nfkb1tm1Bal/Nfkb1tm1Bal
(B6.Cg-Nfkb1tm1Bal/J)
abnormal B cell physiology J:113556
Nfkb1tm1Bal/Nfkb1tm1Bal
Nfkb2tm1Sbn/Nfkb2tm1Sbn

(involves: 129P2/OlaHsd * 129S4/SvJae)
abnormal immune system organ morphology J:45119
abnormal macrophage physiology J:45119
abnormal osteoclast differentiation J:45119
abnormal spleen morphology J:45119
abnormal thymus cortex morphology J:45119
abnormal thymus medulla morphology J:45119
absent lymph nodes J:45119
absent spleen white pulp J:45119
arrested B cell differentiation J:45119
decreased B cell number J:45119
decreased CD4-positive, alpha-beta T cell number J:45119
decreased CD8-positive, alpha-beta T cell number J:45119
decreased dendritic cell number J:45119
decreased double-positive T cell number J:45119
decreased mature B cell number J:45119
decreased osteoclast cell number J:45119
decreased single-positive T cell number J:45119
decreased T cell number J:45119
increased granulocyte number J:45119
increased macrophage cell number J:45119
thymus hypoplasia J:45119
Nfkb1tm1Bal/Nfkb1tm1Bal
Reltm1Grd/Reltm1Grd

(involves: 129P2/OlaHsd * 129S1/Sv)
abnormal immune system physiology J:113514
decreased interleukin-12 secretion J:113514
Nfkb1tm1Bal/Nfkb1tm1Bal
Relatm1Bal/Rela+

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
cecum inflammation J:67107
increased susceptibility to bacterial infection J:67107
large intestinal inflammation J:67107
peritoneal inflammation J:67107
Nfkb1tm1Bal/Nfkb1tm1Bal
Relatm1Bal/Relatm1Bal

(involves: 129P2/OlaHsd * 129S4/SvJae)
abnormal dendritic cell differentiation J:113514
decreased dendritic cell number J:113514
Nfkb1tm1Bal/Nfkb1tm1Bal
Tg(Tnfsf13b)1Fma/?

(B6.Cg-Nfkb1tm1Bal Tg(Tnfsf13b)1Fma)
abnormal B cell activation J:113556
abnormal class switch recombination J:113556
decreased marginal zone B cell number J:113556
immune system phenotype J:113556
increased transitional stage B cell number J:113556
Nfkb1tm1Brv/Nfkb1tm1Brv
(involves: 129S1/Sv)
abnormal cytokine secretion J:46912
abnormal humoral immune response J:46912
abnormal inflammatory response J:46912
abnormal lymph organ size J:46912
abnormal lymphocyte physiology J:46912
decreased IgG3 level J:46912
decreased interleukin-2 secretion J:46912
decreased interleukin-4 secretion J:46912
decreased single-positive T cell number J:46912
decreased T cell proliferation J:46912
decreased tumor necrosis factor secretion J:46912
enlarged lymph nodes J:46912
enlarged spleen J:46912
increased B cell proliferation J:46912
increased IgE level J:46912
increased IgG1 level J:46912
increased immunoglobulin level J:46912
increased susceptibility to bacterial infection J:46912
liver inflammation J:46912
lung inflammation J:46912
myeloid hyperplasia J:46912
Nfkb1tm1Brv/Nfkb1tm1Brv
(involves: 129S1/Sv * C57BL/6)
decreased osteoclast cell number J:44112
Nfkb1tm1Brv/Nfkb1tm1Brv
Nfkb2tm1Brv/Nfkb2+

(involves: 129S1/Sv * C57BL/6)
abnormal osteoclast differentiation J:44112
decreased osteoclast cell number J:44112
Nfkb1tm1Brv/Nfkb1tm1Brv
Nfkb2tm1Brv/Nfkb2tm1Brv

(involves: 129S1/Sv * C57BL/6)
abnormal cytokine secretion J:44112
abnormal osteoclast differentiation J:44112
decreased interleukin-6 secretion J:44112
decreased osteoclast cell number J:44112
increased macrophage cell number J:44112
Nfkb1tm1Sley/Nfkb1tm1Sley
(involves: 129S4/SvJae * 129S8/SvEv)
abnormal inguinal lymph node morphology J:142340
absent inguinal lymph nodes J:142340
decreased circulating interleukin-2 level J:142340
decreased memory T cell number J:142340
decreased regulatory T cell number J:142340
decreased T cell proliferation J:142340
small inguinal lymph nodes J:142340
Nfkb1tm1Sley/Nfkb1tm1Sley
(involves: 129S4/SvJae * 129S8/SvEv * C57BL/6)
decreased memory T cell number J:142340
decreased NK T cell number J:142340
decreased regulatory T cell number J:142340
Nfkb1tm1Sley/Nfkb1tm1Sley
(involves: 129S4/SvJae)
decreased tumor necrosis factor secretion J:196528
Nfkb2Lym1/Nfkb2+
(BALB/c-Nfkb2Lym1)
abnormal lymph node morphology J:154812
abnormal mesenteric lymph node morphology J:154812
abnormal spleen white pulp morphology J:154812
absent axillary lymph nodes J:154812
absent brachial lymph nodes J:154812
absent cervical lymph nodes J:154812
absent inguinal lymph nodes J:154812
absent Peyer's patches J:154812
decreased lymph node number J:154812
increased lymphocyte cell number J:154812
liver inflammation J:154812
lung inflammation J:154812
Nfkb2Lym1/Nfkb2+
(involves: BALB/c)
abnormal B cell differentiation J:188560
Nfkb2Lym1/Nfkb2+
Otub1tm1c(EUCOMM)Hmgu/Otub1tm1c(EUCOMM)Hmgu
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * C57BL/6N)
immune system phenotype J:280549
Nfkb2Lym1/Nfkb2Lym1
(involves: BALB/c)
abnormal class switch recombination J:154812
abnormal lymph node morphology J:154812
abnormal osteoclast differentiation J:154812
abnormal peripheral lymph node morphology J:154812
abnormal plasma cell differentiation J:154812
abnormal spleen follicular dendritic cell network J:154812
abnormal spleen periarteriolar lymphoid sheath morphology J:154812
abnormal spleen primary B follicle morphology J:154812
abnormal spleen white pulp morphology J:154812
abnormal T cell differentiation J:154812
abnormal thymus cell ratio J:154812
abnormal thymus physiology J:154812
abnormal thymus size J:154812
absent axillary lymph nodes J:154812
absent brachial lymph nodes J:154812
absent cervical lymph nodes J:154812
absent inguinal lymph nodes J:154812
absent mesenteric lymph nodes J:154812
absent Peyer's patches J:154812
autoimmune response J:154812
decreased B cell proliferation J:154812
decreased follicular B cell number J:154812
decreased IgA level J:154812
decreased IgG1 level J:154812
decreased IgG2b level J:154812
decreased IgM level J:154812
decreased immunoglobulin level J:154812
decreased lymph node number J:154812
decreased marginal zone B cell number J:154812
decreased mature B cell number J:154812
decreased transitional stage B cell number J:154812
enlarged spleen J:154812
increased CD4-positive, alpha-beta T cell number J:154812
increased CD8-positive, alpha-beta T cell number J:154812
increased double-negative T cell number J:154812
increased double-positive T cell number J:154812
increased spleen red pulp amount J:154812
increased spleen weight J:154812
increased transitional stage B cell number J:154812
liver inflammation J:154812
lung inflammation J:154812
Nfkb2m2Btlr/Nfkb2m2Btlr
(C57BL/6J-Nfkb2m2Btlr)
increased B-1a cell number J:221493
Nfkb2m3Btlr/Nfkb2m3Btlr
(C57BL/6J-Nfkb2m3Btlr)
abnormal B cell differentiation J:274960
abnormal CD4-positive T cell differentiation J:274960
abnormal CD8-positive, alpha-beta T cell differentiation J:274960
abnormal T cell differentiation J:274960
decreased B cell number J:274960
decreased CD4-positive, alpha-beta T cell number J:274960
decreased effector memory CD8-positive, alpha-beta T cell number J:274960
decreased NK cell number J:274960
increased B-1 B cell number J:274960
increased CD4-positive, alpha-beta T cell number J:274960
increased CD8-positive, alpha-beta T cell number J:274960
increased CD8-positive, naive alpha-beta T cell number J:274960
increased T cell number J:274960
Nfkb2M4Btlr/Nfkb2M4Btlr
(C57BL/6J-Nfkb2M4Btlr)
increased CD4-positive, alpha-beta T cell number J:274961
increased CD8-positive, alpha-beta T cell number J:274961
increased T cell number J:274961
Nfkb2m5Btlr/Nfkb2m5Btlr
(C57BL/6J-Nfkb2m5Btlr)
increased B-1 B cell number J:274962
Nfkb2tm1Brv/Nfkb2tm1Brv
(involves: 129S1/Sv * C57BL/6)
abnormal cytokine secretion J:43469
abnormal lymph node B cell domain morphology J:43469
abnormal lymph node cortex morphology J:43469
abnormal lymphocyte cell number J:43469
abnormal T cell number J:43469
abnormal T cell subpopulation ratio J:43469
abnormal thymus corticomedullary boundary morphology J:43469
decreased double-positive T cell number J:43469
decreased spleen weight J:43469
enlarged lymph nodes J:43469
increased B cell proliferation J:43469
increased granulocyte number J:43469
increased interleukin-2 secretion J:43469
increased interleukin-4 secretion J:43469
increased interleukin-10 secretion J:43469
increased T cell proliferation J:43469
increased tumor necrosis factor secretion J:43469
intermingled spleen red and white pulp J:43469
spleen atrophy J:43469
spleen hypoplasia J:43469
thymus atrophy J:43469
Nfkb2tm1Rsch/Nfkb2tm1Rsch
(involves: 129P2/OlaHsd)
abnormal myeloid dendritic cell morphology J:77049
abnormal Peyer's patch follicle morphology J:77049
abnormal Peyer's patch germinal center morphology J:77049
abnormal Peyer's patch morphology J:77049
abnormal Peyer's patch T cell area morphology J:77049
decreased B cell number J:77049
decreased dendritic cell number J:77049
decreased myeloid dendritic cell number J:77049
increased plasmacytoid dendritic cell number J:77049
small Peyer's patches J:77049
Nfkb2tm1Sbn/Nfkb2tm1Sbn
(involves: 129S4/SvJae * C57BL/6)
abnormal class switch recombination J:45437
abnormal immunoglobulin level J:45437
abnormal lymphocyte cell number J:45437
abnormal metallophilic macrophage morphology J:45437
abnormal spleen B cell follicle morphology J:45437
abnormal spleen marginal zone macrophage morphology J:45437
abnormal spleen marginal zone morphology J:45437
abnormal spleen white pulp morphology J:45437
absent spleen germinal center J:45437
decreased B cell number J:45437
decreased IgA level J:45437
decreased IgG1 level J:45437
decreased IgG2a level J:45437
decreased IgG2b level J:45437
increased IgM level J:45437
increased susceptibility to parasitic infection J:45437
increased T cell number J:45437
Nfkb2tm2Brv/Nfkb2tm2Brv
(involves: 129S1/Sv * C57BL/6)
abnormal lymph node morphology J:76380
abnormal metallophilic macrophage morphology J:76380
abnormal spleen morphology J:76380
absent lymph node germinal center J:76380
absent spleen germinal center J:76380
absent spleen marginal zone J:76380
decreased B cell number J:76380
decreased B cell proliferation J:76380
decreased IgA level J:76380
decreased IgG1 level J:76380
decreased IgG3 level J:76380
increased CD4-positive, alpha-beta T cell number J:76380
increased CD8-positive, alpha-beta T cell number J:76380
increased IgG2a level J:76380
increased IgM level J:76380
increased splenocyte apoptosis J:76380
Nfkb2tm2Brv/Nfkb2tm2Brv
(involves: 129S1/Sv)
abnormal gamma-delta T cell morphology J:169863
decreased gamma-delta T cell number J:169863
Nfkb2tm2Brv/Nfkb2tm2Brv
Tg(Tnfsf13b)1Fma/?

(B6.Cg-Nfkb2tm2Brv Tg(Tnfsf13b)1Fma)
abnormal B cell activation J:113556
absent spleen marginal zone J:113556
decreased marginal zone B cell number J:113556
immune system phenotype J:113556
Nfkb2tm2Brv/Nfkb2tm2Brv
Traf3tm1Bal/Traf3tm1Bal

(involves: 129S1/Sv * 129S4/SvJae * C57BL/6)
immune system phenotype J:124635
Nfkb2xdr/Nfkb2xdr
(C57BL/6JSfdAnu-Nfkb2xdr/Anu)
abnormal metallophilic macrophage morphology J:79725
abnormal peripheral lymph node morphology J:79725
abnormal spleen follicular dendritic cell network J:79725
abnormal spleen morphology J:79725
abnormal spleen secondary B follicle morphology J:79725
decreased B-2 B cell number J:79725
decreased follicular B cell number J:79725
decreased marginal zone B cell number J:79725
decreased mature B cell number J:79725
decreased transitional stage T2 B cell number J:79725
increased B-1 B cell number J:79725
Nfkb2xdr/Nfkb2xdr
(involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd * NOD)
decreased B cell number J:79725
Nfkbiatm1.1Kbp/Nfkbiatm1.1Kbp
(involves: 129P2/OlaHsd * C57BL/6)
abnormal granulocyte morphology J:97945
increased granulocyte number J:97945
Nfkbiatm1.1Pjc/Nfkbiatm1.1Pjc
(involves: C57BL/6)
abnormal circulating cytokine level J:163686
abnormal T cell activation J:163686
abnormal T cell number J:163686
autoimmune response J:163686
chronic inflammation J:163686
decreased CD4-positive, alpha-beta T cell number J:163686
decreased CD8-positive, alpha-beta T cell number J:163686
increased activated T cell number J:163686
increased anti-insulin autoantibody level J:163686
increased anti-nuclear antigen antibody level J:163686
increased circulating interleukin-1 alpha level J:163686
increased circulating interleukin-17 level J:163686
increased circulating tumor necrosis factor level J:163686
increased double-positive T cell number J:163686
increased memory T cell number J:163686
increased susceptibility to bacterial infection induced morbidity/mortality J:163686
increased T cell apoptosis J:163686
increased T cell proliferation J:163686
increased thymocyte number J:163686
Nfkbiatm1.1Smiy/Nfkbia+
(B6.129-Nfkbiatm1.1Smiy)
decreased B cell number J:168977
decreased follicular B cell number J:168977
decreased marginal zone B cell number J:168977
decreased transitional stage T2 B cell number J:168977
increased pro-B cell number J:168977
small Peyer's patches J:168977
Nfkbiatm1.1Smiy/Nfkbiatm1.1Smiy
(B6.129-Nfkbiatm1.1Smiy)
abnormal B cell differentiation J:168977
abnormal marginal zone B cell morphology J:168977
decreased B cell number J:168977
decreased B cell proliferation J:168977
decreased B-2 B cell number J:168977
decreased CD4-positive, alpha-beta memory T cell number J:168977
decreased follicular B cell number J:168977
decreased IgA level J:168977
decreased IgG1 level J:168977
decreased IgG2b level J:168977
decreased marginal zone B cell number J:168977
decreased mature B cell number J:168977
decreased Peyer's patch number J:168977
decreased regulatory T cell number J:168977
decreased transitional stage T2 B cell number J:168977
increased activation-induced B cell apoptosis J:168977
increased immature B cell number J:168977
increased pre-B cell number J:168977
increased pro-B cell number J:168977
small Peyer's patches J:168977
Nfkbiatm1Bal/Nfkbiatm1Bal
(involves: 129S4/SvJae * C57BL/6J)
abnormal granulocyte differentiation J:30058
decreased double-positive T cell number J:30058
increased leukocyte cell number J:30058
spleen atrophy J:30058
thymus atrophy J:30058
Nfkbiatm1Bal/Nfkbiatm1Bal
Nfkbietm1Syme/Nfkbietm1Syme

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2)
abnormal B cell differentiation J:88142
abnormal T cell differentiation J:88142
decreased immature B cell number J:88142
decreased pre-B cell number J:88142
increased B cell apoptosis J:88142
increased T cell apoptosis J:88142
Nfkbiatm1Fey/Nfkbiatm1Fey
(involves: 129S6/SvEvTac * C57BL/6)
abnormal B cell differentiation J:110817
abnormal humoral immune response J:110817
absent spleen germinal center J:110817
decreased double-negative T cell number J:110817
decreased T cell proliferation J:110817
decreased thymocyte number J:110817
increased B cell proliferation J:110817
increased IgA level J:110817
increased IgE level J:110817
increased IgG level J:110817
increased single-positive T cell number J:110817
small spleen J:110817
thymus atrophy J:110817
Nfkbiatm1Stw/Nfkbiatm1Stw
(involves: 129S1/Sv)
abnormal macrophage physiology J:32527
abnormal myelopoiesis J:32527
abnormal tumor necrosis factor level J:32527
dermatitis J:32527
increased macrophage cell number J:32527
increased monocyte cell number J:32527
Nfkbibtm1.2Rsch/Nfkbibtm1.2Rsch
(B6.129P2-Nfkbibtm1.2Rsch)
abnormal cytokine secretion J:176877
abnormal immune system morphology J:176877
abnormal immune system physiology J:176877
abnormal interleukin-1 beta secretion J:176877
abnormal interleukin-6 secretion J:176877
abnormal tumor necrosis factor secretion J:176877
decreased B cell number J:176877
decreased susceptibility to bacterial infection induced morbidity/mortality J:176877
increased macrophage cell number J:176877
increased marginal zone B cell number J:176877
increased memory T cell number J:176877
Nfkbibtm1Bal/Nfkbibtm1Bal
(B6.129S1-Nfkbibtm1Bal)
decreased circulating interleukin-1 beta level J:163302
decreased circulating interleukin-6 level J:163302
decreased circulating tumor necrosis factor level J:163302
decreased susceptibility to bacterial infection induced morbidity/mortality J:163302
decreased susceptibility to endotoxin shock J:163302
decreased susceptibility to induced arthritis J:163302
decreased tumor necrosis factor secretion J:163302
Nfkbidm1Btlr/Nfkbidm1Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
absent marginal zone B cells J:185495
decreased B cell proliferation J:185495
decreased B-1 B cell number J:185495
decreased B-1a cell number J:185495
decreased IgG1 level J:185495
decreased IgG3 level J:185495
decreased IgG level J:185495
decreased IgM level J:185495
immune system phenotype J:185495
increased B cell apoptosis J:185495
Nfkbidtm1a(EUCOMM)Wtsi/Nfkbid+
(C57BL/6N-Nfkbidtm1a(EUCOMM)Wtsi/Cnrm)
decreased B cell number J:165965
Nfkbidtm1a(EUCOMM)Wtsi/Nfkbidtm1a(EUCOMM)Wtsi
(involves: C57BL/6N)
abnormal class switch recombination J:185495
decreased IgG level J:185495
decreased IgM level J:185495
Nfkbidtm1Clay/Nfkbidtm1Clay
(involves: 129S6/SvEvTac * C57BL/6)
abnormal NK cell physiology J:132071
abnormal thymocyte activation J:132071
decreased interferon-gamma secretion J:132071
decreased interleukin-2 secretion J:132071
decreased T cell proliferation J:132071
Nfkbidtm1Ktak/Nfkbidtm1Ktak
(involves: 129P2/OlaHsd * C57BL/6)
increased interferon-gamma secretion J:113334
increased interleukin-6 secretion J:113334
increased interleukin-12 secretion J:113334
increased interleukin-12b secretion J:113334
increased susceptibility to endotoxin shock J:113334
increased susceptibility to induced colitis J:113334
Nfkbietm1Syme/Nfkbietm1Syme
(either: (involves: 129P2/OlaHsd * C57BL/6 * DBA/2) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal double-negative T cell morphology J:88538
increased IgG1 level J:88538
increased IgM level J:88538
Nfkbiztm1.1Muta/Nfkbiztm1.1Muta
Tg(CAG-cre)13Miya/?

(involves: C57BL/6)
dermatitis J:194832
Nfkbiztm1.1Muta/Nfkbiztm1.1Muta
Tg(KRT5-cre)1Tak/?

(involves: C3H * C57BL/6)
dermatitis J:194832
Nfkbiztm1.1Muta/Nfkbiztm1.1Muta
Tg(Lck-cre)1Jtak/?

(involves: C57BL/6)
immune system phenotype J:194832
Nfkbiztm1Aki/Nfkbiz+
Stat6tm1Aki/Stat6tm1Aki

(C.129P2-Stat6tm1Aki Nfkbiztm1Aki)
skin inflammation J:141704
Nfkbiztm1Aki/Nfkbiztm1Aki
(involves: 129P2/OlaHsd)
abnormal cytokine secretion J:91297
abnormal immune system organ morphology J:194832
abnormal immune system physiology J:194832
abnormal leukocyte physiology J:91297
abnormal lymph node cell ratio J:194832
abnormal lymphocyte morphology J:194832
abnormal T-helper 1 cell morphology J:194832
abnormal tumor necrosis factor secretion J:91297
blepharitis J:96363
conjunctivitis J:96363
corneal limbitis J:96363
decreased interleukin-6 secretion J:91297
decreased interleukin-12 secretion J:91297
dermatitis J:194832, J:91297
enlarged lymph nodes J:194832
enlarged spleen J:194832
eye inflammation J:96363
increased immunoglobulin level J:194832
interstitial pneumonia J:194832
lacrimal gland inflammation J:194832
periocular dermatitis J:194832
Nfkbiztm1Aki/Nfkbiztm1Aki
(C.129P2-Nfkbiztm1Aki)
blepharitis J:141704
conjunctivitis J:141704
dermatitis J:141704
eye inflammation J:141704
increased IgE level J:141704
perioral dermatitis J:141704
skin inflammation J:141704
Nfkbiztm1Aki/Nfkbiztm1Aki
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129P2/OlaHsd * 129S/SvEv)
immune system phenotype J:194832
Nfkbiztm1Aki/Nfkbiztm1Aki
Stat6tm1Aki/Stat6tm1Aki

(C.129P2-Stat6tm1Aki Nfkbiztm1Aki)
blepharitis J:141704
dermatitis J:141704
eye inflammation J:141704
skin inflammation J:141704
Nfkbiztm1Aki/Nfkbiztm1Aki
Tnftm1Sek/Tnftm1Sek

(involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj)
conjunctivitis J:194832
dermatitis J:194832
Nfkbiztm1Mamo/Nfkbiztm1Mamo
(involves: 129S7/SvEvBrd)
dermatitis J:95040
increased IgE level J:95040
Ngfrtm1Jae/Ngfrtm1Jae
(B6.129S4-Ngfrtm1Jae)
abnormal Kupffer cell morphology J:120368
increased susceptibility to experimental autoimmune encephalomyelitis J:112769
Ngfrtm1Jae/Ngfrtm1Jae
(involves: 129S4/SvJae)
abnormal tumor necrosis factor level J:157549
Ngptm1b(KOMP)Wtsi/Ngptm1b(KOMP)Wtsi
(C57BL/6N-Ngptm1b(KOMP)Wtsi/Bay)
increased spleen weight J:211773
Nhej1tm1.1Ics/Nhej1+
(involves: 129 * C57BL/6)
decreased thymocyte number J:194422
Nhej1tm1.1Ics/Nhej1tm1.1Ics
(involves: 129 * C57BL/6)
abnormal T cell receptor V(D)J recombination J:194422
decreased lymphocyte cell number J:194422
decreased NK T cell number J:194422
decreased thymocyte number J:194422
increased thymocyte apoptosis J:194422
Nhej1tm1.1Ics/Nhej1tm1.1Ics
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129S2/SvPas * C57BL/6)
abnormal T cell receptor V(D)J recombination J:194422
decreased NK T cell number J:194422
decreased thymocyte apoptosis J:194422
Nhej1tm1Fwa/Nhej1tm1Fwa
(involves: 129)
abnormal class switch recombination J:138774
decreased IgG1 level J:138774
decreased IgG3 level J:138774
increased IgM level J:138774
spleen hypoplasia J:138774
thymus hypoplasia J:138774
Nhej1tm1Fwa/Nhej1tm1Fwa
Xrcc5tm1Nus/Xrcc5tm1Nus

(involves: 129S6/SvEvTac * C57BL/6)
athymia J:236776
small spleen J:236776
Nherf1em1(IMPC)H/Nherf1em1(IMPC)H
(C57BL/6NTac-Nherf1em1(IMPC)H/H)
increased basophil cell number J:211773
increased leukocyte cell number J:211773
Nhlh1tm1b(KOMP)Wtsi/Nhlh1+
(C57BL/6N-Nhlh1tm1b(KOMP)Wtsi/Tcp)
enlarged lymph nodes J:211773
Nhlh2tm1b(KOMP)Mbp/Nhlh2tm1b(KOMP)Mbp
(C57BL/6N-Nhlh2tm1b(KOMP)Mbp/Tcp)
increased spleen weight J:211773
Nhsl2em1(IMPC)Tcp/Y
(C57BL/6N-Nhsl2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Nhsl2em1(IMPC)Tcp/Nhsl2em1(IMPC)Tcp
(C57BL/6N-Nhsl2em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
Niban1em1(IMPC)Ccpcz/Niban1em1(IMPC)Ccpcz
(C57BL/6N-Niban1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
Niban3em1(IMPC)Mbp/Niban3em1(IMPC)Mbp
(C57BL/6N-Niban3em1(IMPC)Mbp/MbpMmucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Niban3tm1Jyw/Niban3tm1Jyw
(B6.Cg-Niban3tm1Jyw)
abnormal B cell differentiation J:282961
abnormal B cell physiology J:282961
abnormal class switch recombination J:282961
abnormal transitional stage B cell morphology J:282961
decreased B-1a cell number J:282961
decreased IgA level J:282961
decreased IgG2c level J:282961
enhanced humoral immune response J:282961
increased B cell number J:282961
increased B cell proliferation J:282961
increased follicular B cell number J:282961
increased IgG1 level J:282961
increased IgG3 level J:282961
increased IgG level J:282961
increased IgM level J:282961
increased transitional stage T2 B cell number J:282961
Nid2Gt(GST011)Byg/Nid2Gt(GST011)Byg
(involves: 129P2/OlaHsd)
osteoarthritis J:229684
Ninj1tm1Gto/Ninj1+
(B6.129P2-Ninj1tm1Gto)
decreased susceptibility to experimental autoimmune encephalomyelitis J:209516
Ninj1tm1Gto/Ninj1tm1Gto
(B6.129P2-Ninj1tm1Gto)
abnormal leukocyte adhesion J:209516
abnormal leukocyte physiology J:209516
decreased susceptibility to experimental autoimmune encephalomyelitis J:209516
impaired macrophage chemotaxis J:209516
Nipal3tm1Pbfd/Nipal3tm1Pbfd
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J))
decreased IgM level J:152829
decreased NK cell number J:152829
increased IgA level J:152829
increased IgE level J:152829
increased IgG2a level J:152829
increased IgM level J:152829
NipblGt(RRS564)Byg/Nipbl+
(involves: 129P2/OlaHsd * CD-1)
abnormal inflammatory response J:154117
eye inflammation J:154117
NipblGt(RRS564)Byg/Nipbl+
(involves: 129P2/OlaHsd * C57BL/6J * CD-1)
abnormal chemokine level J:297059
Nipsnap3atm1b(KOMP)Wtsi/Nipsnap3atm1b(KOMP)Wtsi
(C57BL/6N-Nipsnap3atm1b(KOMP)Wtsi/Wtsi)
increased effector memory T-helper cell number J:211773
Nischedsn/Nischedsn
(C3H.B6-Nischedsn)
increased susceptibility to otitis media J:244907
Nischedsn/NischV33A
(involves: BALB/c * C3H/HeH * C57BL/6J)
increased susceptibility to otitis media J:244907
NischV33A/NischV33A
(involves: BALB/c * C57BL/6J)
increased susceptibility to otitis media J:244907
Nkaptm1.1Viss/Y
Tg(Lck-cre)1Cwi/0

(involves: 129S1/Sv * 129X1/SvJ)
arrested T cell differentiation J:165961
decreased CD4-positive, alpha-beta T cell number J:165961
decreased CD8-positive, alpha-beta T cell number J:165961
decreased DN4 thymocyte number J:165961
decreased double-positive T cell number J:165961
decreased thymocyte number J:165961
increased DN3 thymocyte number J:165961
thymus hypoplasia J:165961
Nkg7tm1.1(KOMP)Vlcg/Nkg7tm1.1(KOMP)Vlcg
(C57BL/6N-Nkg7tm1.1(KOMP)Vlcg/Ucd)
increased eosinophil cell number J:211773
Nkg7tm1.1(KOMP)Vlcg/Nkg7tm1.1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:301637
abnormal mononuclear cell morphology J:301637
decreased CD4-positive, alpha-beta T cell number J:301637
decreased circulating interferon-gamma level J:301637
decreased circulating tumor necrosis factor level J:301637
decreased susceptibility to parasitic infection induced morbidity/mortality J:301637
decreased T helper 1 cell number J:301637
increased susceptibility to parasitic infection induced morbidity/mortality J:301637
Nktcn1C57BL/6J/Nktcn1C57BL/6J
(involves: C57BL/6J * NOD.B6-(D6Mit105-D6Mit135))
increased NK T cell number J:85376
Nktcn1C57BL/6J/Nktcn1C57BL/6J
(NOD.B6-(D1Mit369-D1Mit155)(D6Mit105-D6Mit135))
abnormal T cell differentiation J:137521
increased NK T cell number J:137521
Nktcn1C57BL/6J/Nktcn1NOD/ShiLt
(involves: C57BL/6J * NOD.B6-(D6Mit105-D6Mit135))
increased NK T cell number J:85376
Nktcn2C57BL/6J/Nktcn2C57BL/6J
(involves: C57BL/6J * NOD.B6-(D6Mit105-D6Mit135))
increased NK T cell number J:85376
Nktcn2C57BL/6J/Nktcn2NOD/ShiLt
(involves: C57BL/6J * NOD.B6-(D6Mit105-D6Mit135))
increased NK T cell number J:85376
Nkx2-3tm1Hha/Nkx2-3tm1Hha
(involves: 129S4/SvJae * C57BL/6)
abnormal spleen primary B follicle morphology J:54198
abnormal splenic cell ratio J:54198
absent spleen J:54198
absent spleen marginal zone J:54198
decreased spleen white pulp amount J:54198
small spleen J:54198
Nkx2-3tm1Hha/Nkx2-3tm1Hha
(involves: 129S4/SvJae)
abnormal leukocyte migration J:62129
abnormal marginal zone B cell morphology J:62129
abnormal mesenteric lymph node morphology J:62129
abnormal metallophilic macrophage morphology J:62129
abnormal Peyer's patch follicle morphology J:62129
abnormal spleen marginal sinus morphology J:62129
abnormal spleen marginal zone macrophage morphology J:62129
abnormal spleen morphology J:62129
abnormal spleen periarteriolar lymphoid sheath morphology J:62129
absent marginal zone B cells J:62129
absent spleen marginal zone J:62129
decreased B cell number J:62129
decreased lymphocyte cell number J:62129
decreased Peyer's patch number J:62129
decreased spleen weight J:62129
decreased spleen white pulp amount J:62129
decreased T cell number J:62129
intermingled spleen red and white pulp J:62129
small Peyer's patches J:62129
small spleen J:62129
Nkx2-3tm1Rph/Nkx2-3tm1Rph
(involves: 129S1/Sv * C57BL/6)
abnormal gut-associated lymphoid tissue morphology J:64018
abnormal leukocyte migration J:64018
abnormal mesenteric lymph node morphology J:64018
abnormal metallophilic macrophage morphology J:64018
abnormal spleen B cell follicle morphology J:64018
abnormal spleen periarteriolar lymphoid sheath morphology J:64018
abnormal spleen red pulp morphology J:64018
absent spleen J:64018
absent spleen marginal zone J:64018
decreased CD4-positive, alpha-beta T cell number J:64018
decreased Peyer's patch number J:64018
decreased plasma cell number J:64018
increased leukocyte cell number J:64018
small Peyer's patches J:64018
small spleen J:64018
spleen atrophy J:64018
Nkx2-5tm1(cre)Rjs/Nkx2-5+
Tbx1tm1Bld/Tbx1tm3Bld

(involves: 129S7/SvEvBrd * C57BL/6)
small thymus J:91013
Nkx2-5tm1Wehi/Nkx2-5+
(involves: 129P2/OlaHsd)
spleen hypoplasia J:184521
Nkx2-5tm2(cre)Rph/Nkx2-5+
Pbx1tm1.1Koss/Pbx1tm1.1Koss

(involves: 129P2/OlaHsd * 129S1/Sv)
abnormal spleen morphology J:184521
spleen hypoplasia J:184521
Nkx2-5tm2(cre)Rph/Nkx2-5tm4Rph
(involves: 129S1/Sv)
spleen hypoplasia J:184521
Nkx3-2tm1.1Tlu/Nkx3-2tm1.1Tlu
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J))
absent spleen J:55583
Nkx3-2tm1Bobh/Nkx3-2tm1Bobh
(involves: 129P2/OlaHsd * C57BL/6)
absent spleen J:57112
Nkx3-2tm1Tlu/Nkx3-2tm1Tlu
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J))
absent spleen J:55583
Nkx3-2tm1Tno/Nkx3-2tm1Tno
(involves: 129S4/SvJae * C57BL/6J)
absent spleen J:77612
Nle1tm1Cba/Nle1tm1.1Cota
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S2/SvPas)
immune system phenotype J:204063
Nle1tm1Cba/Nle1tm1.1Cota
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal immune system organ morphology J:204063
decreased granulocyte number J:204063
decreased macrophage cell number J:204063
decreased NK cell number J:204063
decreased T cell number J:204063
spleen hypoplasia J:204063
thymus hypoplasia J:204063
Nlgn3em1(IMPC)Rbrc/Y
(C57BL/6NJcl-Nlgn3em1(IMPC)Rbrc/Rbrc)
abnormal eosinophil cell number J:211773
Nlgn3em1(IMPC)Rbrc/Nlgn3em1(IMPC)Rbrc
(C57BL/6NJcl-Nlgn3em1(IMPC)Rbrc/Rbrc)
abnormal neutrophil cell number J:211773
Nlktm1Tbo/Nlktm1Tbo
(129S1/Sv-Nlktm1Tbo)
abnormal bone marrow development J:73353
abnormal immune system organ morphology J:73353
decreased double-positive T cell number J:73353
decreased gamma-delta T cell number J:73353
decreased lymphocyte cell number J:73353
decreased NK cell number J:73353
decreased pro-B cell number J:73353
decreased thymocyte number J:73353
impaired myelopoiesis J:73353
small lymph nodes J:73353
spleen hypoplasia J:73353
thymus hypoplasia J:73353
Nlrc3tm1Bhk/Nlrc3tm1Bhk
(B6.129S6-Nlrc3tm1Bhk)
increased circulating interleukin-6 level J:187586
increased circulating tumor necrosis factor level J:187586
increased monocyte cell number J:187586
increased susceptibility to endotoxin shock J:187586
increased tumor necrosis factor secretion J:187586
Nlrc4em1Vnce/Nlrc4em1Vnce
(C57BL/6-Nlrc4em1Vnce)
decreased inflammatory response J:294930
increased susceptibility to bacterial infection induced morbidity/mortality J:294930
Nlrc4em1Vnce/Nlrc4em1Vnce
Nlrp3tm1Vmd/Nlrp3tm1Vmd

(involves: C57BL/6J * C57BL/6N)
decreased inflammatory response J:294930
Nlrc4em2Vnce/Nlrc4em2Vnce
(C57BL/6-Nlrc4em2Vnce)
decreased inflammatory response J:294930
Nlrc4em2Vnce/Nlrc4em2Vnce
Nlrp3tm1Vmd/Nlrp3tm1Vmd

(involves: C57BL/6J * C57BL/6N)
decreased inflammatory response J:294930
Nlrc4em3Vnce/Nlrc4em3Vnce
(C57BL/6-Nlrc4em3Vnce)
immune system phenotype J:294930
Nlrc4m1Btlr/Nlrc4+
(C57BL/6J-Nlrc4m1Btlr)
decreased interleukin-1 beta secretion J:225933
Nlrc4m1Btlr/Nlrc4m1Btlr
(C57BL/6J-Nlrc4m1Btlr)
decreased interleukin-1 beta secretion J:225933
Nlrc4tm1Gln/Nlrc4tm1Gln
(involves: 129S5/SvEvBrd)
immune system phenotype J:173245
Nlrc4tm1Gln/Nlrc4tm1Gln
Slc11a1s/Slc11a1s

(B6.129S5-Nlrc4tm1Gln)
increased susceptibility to bacterial infection J:124378
Nlrc4tm1Gne/Nlrc4tm1Gne
(involves: C57BL/6N)
immune system phenotype J:189256
Nlrc4tm1Nnz/Nlrc4tm1Nnz
(involves: 129 * C57BL/6J)
abnormal macrophage physiology J:112671, J:117251
increased susceptibility to bacterial infection J:117251
Nlrc4tm1Vmd/Nlrc4tm1Vmd
(C57BL/6N-Nlrc4tm1Vmd)
decreased interleukin-1 beta secretion J:91292
Nlrc4tm1Vmd/Nlrc4tm1Vmd
(involves: C57BL/6N)
abnormal cytokine secretion J:106976
abnormal response to infection J:106976
Nlrc4tm1Vmd/Nlrc4tm1Vmd
Nlrp3tm1Vmd/Nlrp3tm1Vmd

(C57BL/6-Nlrp3tm1Vmd Nlrc4tm1Vmd)
decreased interleukin-1 beta secretion J:160545
Nlrc5tm1.1Ggaur/Nlrc5tm1.1Ggaur
(involves: BALB/cJ)
abnormal T cell physiology J:184076
decreased CD8-positive, alpha-beta T cell number J:184076
enlarged spleen J:184076
immune system phenotype J:184076
Nlrc5tm1Aki/Nlrc5tm1Aki
(Not Specified)
immune system phenotype J:168788
Nlrc5tm1Itl/Nlrc5tm1Itl
(C57BL/6-Nlrc5tm1Itl)
decreased interferon-beta secretion J:188857
decreased interleukin-6 secretion J:188857
immune system phenotype J:188857
Nlrp1am1Btlr/Nlrp1am1Btlr
(C57BL/6J-Nlrp1am1Btlr)
decreased B cell number J:265173
decreased B-1 B cell number J:265173
decreased B-1b cell number J:265173
decreased B-2 B cell number J:265173
decreased CD8-positive, alpha-beta T cell number J:265173
decreased central memory CD8 positive, alpha-beta T cell number J:265173
decreased NK cell number J:265173
decreased single-positive T cell number J:265173
decreased T cell number J:265173
increased effector memory CD8-positive, alpha-beta T cell number J:265173
increased IgE level J:265173
increased macrophage apoptosis J:265173
increased tumor necrosis factor secretion J:265173
Nlrp1am2Btlr/Nlrp1am2Btlr
(C57BL/6J-Nlrp1am2Btlr)
decreased B cell number J:265174
decreased interleukin-1 beta secretion J:265174
decreased NK cell number J:265174
increased dendritic cell number J:265174
increased macrophage apoptosis J:265174
increased neutrophil cell number J:265174
Nlrp1aNeut1/Nlrp1a+
(C.B6-Nlrp1aNeut1)
increased inflammatory response J:191055
liver inflammation J:191055
lung inflammation J:191055
meningitis J:191055
myocarditis J:191055
pancreas inflammation J:191055
Nlrp1aNeut1/Nlrp1aNeut1
(C.B6-Nlrp1aNeut1)
decreased lymphocyte cell number J:191055
decreased macrophage cell number J:191055
enlarged spleen J:191055
increased inflammatory response J:191055
increased macrophage cytokine production J:191055
increased neutrophil cell number J:191055
liver inflammation J:191055
lung inflammation J:191055
meningitis J:191055
myocarditis J:191055
pancreas inflammation J:191055
Nlrp1aNeut1/Nlrp1aNeut1
Pycardtm1Vmd/Pycardtm1Vmd

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal inflammatory response J:191055
increased neutrophil cell number J:191055
Nlrp1btm1Bhk/Nlrp1btm1Bhk
(129S6/SvEvTac-Nlrp1btm1Bhk)
abnormal macrophage physiology J:189777
decreased interleukin-1 alpha secretion J:189777
decreased interleukin-1 beta secretion J:189777
Nlrp2tm1.2Itl/Nlrp2tm1.2Itl
(involves: C57BL/6)
immune system phenotype J:237496
Nlrp3m1Btlr/Nlrp3m1Btlr
(C57BL/6J-Nlrp3m1Btlr)
decreased interleukin-1 beta secretion J:159357
Nlrp3m2Btlr/?
(C57BL/6J-Nlrp3m2Btlr)
abnormal interleukin-1 beta secretion J:164865
Nlrp3m3Btlr/?
(C57BL/6J-Nlrp3m3Btlr)
abnormal interleukin-1 beta secretion J:164866
Nlrp3m4Btlr/Nlrp3m4Btlr
(involves: C57BL/6J)
decreased interleukin-1 beta secretion J:171739
Nlrp3m5Btlr/Nlrp3+
(C57BL/6J-Nlrp3m5Btlr)
decreased interleukin-1 beta secretion J:192651
Nlrp3m5Btlr/Nlrp3m5Btlr
(C57BL/6J-Nlrp3m5Btlr)
decreased interleukin-1 beta secretion J:192651
Nlrp3M6Btlr/Nlrp3+
(C57BL/6J-Nlrp3M6Btlr)
decreased interleukin-1 beta secretion J:216047
Nlrp3M6Btlr/Nlrp3M6Btlr
(C57BL/6J-Nlrp3M6Btlr)
decreased susceptibility to experimental autoimmune encephalomyelitis J:226677
Nlrp3M7Btlr/Nlrp3+
(C57BL/6J-Nlrp3M7Btlr)
abnormal macrophage cytokine production J:216048
decreased interleukin-1 beta secretion J:216048
Nlrp3M7Btlr/Nlrp3M7Btlr
(C57BL/6J-Nlrp3M7Btlr)
abnormal macrophage cytokine production J:216048
decreased interleukin-1 beta secretion J:216048
Nlrp3M8Btlr/Nlrp3+
(C57BL/6J-Nlrp3M8Btlr)
decreased interleukin-1 beta secretion J:217294
Nlrp3M8Btlr/Nlrp3M8Btlr
(C57BL/6J-Nlrp3M8Btlr)
decreased interleukin-1 beta secretion J:217294
Nlrp3M9Btlr/Nlrp3+
(C57BL/6J-Nlrp3M9Btlr)
decreased interleukin-1 beta secretion J:220071
Nlrp3M9Btlr/Nlrp3M9Btlr
(C57BL/6J-Nlrp3M9Btlr)
decreased interleukin-1 beta secretion J:220071
Nlrp3M10Btlr/Nlrp3+
(C57BL/6J-Nlrp3M10Btlr)
decreased interleukin-1 beta secretion J:234254
Nlrp3M10Btlr/Nlrp3M10Btlr
(C57BL/6J-Nlrp3M10Btlr)
decreased interleukin-1 beta secretion J:234254
Nlrp3M11Btlr/Nlrp3M11Btlr
(C57BL/6J-Nlrp3M11Btlr)
decreased interleukin-1 beta secretion J:255211
Nlrp3m12Btlr/Nlrp3m12Btlr
(C57BL/6J-Nlrp3m12Btlr)
decreased interleukin-1 beta secretion J:272150
Nlrp3tm1Bhk/Nlrp3tm1Bhk
(involves: 129S6/SvEvTac)
decreased interleukin-1 beta secretion J:189777
immune system phenotype J:189777
Nlrp3tm1Bhk/Nlrp3tm1Bhk
(B6.129S6-Nlrp3tm1Bhk/J)
decreased interleukin-1 beta secretion J:253629
white adipose tissue inflammation J:256504
Nlrp3tm1Flv/Nlrp3tm1Flv
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal macrophage physiology J:113333
decreased circulating interleukin-1 beta level J:113333
decreased circulating interleukin-18 level J:113333
decreased susceptibility to endotoxin shock J:113333
decreased susceptibility to type IV hypersensitivity reaction J:113333
Nlrp3tm1Flv/Nlrp3tm1Flv
(B6.129S5-Nlrp3tm1Flv)
decreased interleukin-1 beta secretion J:164725
Nlrp3tm1Flv/Nlrp3tm1Flv
(involves: 129S5/SvEvBrd)
decreased susceptibility to induced colitis J:173245
Nlrp3tm1Flv/Nlrp3tm1Flv
Slc11a1s/Slc11a1s

(B6.129S5-Nlrp3tm1Flv)
increased susceptibility to bacterial infection J:124378
Nlrp3tm1Flv/Nlrp3tm1Hhf
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * C57BL/6)
increased inflammatory response J:150054
Nlrp3tm1Hhf/Nlrp3+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal circulating chemokine level J:150054
abnormal circulating cytokine level J:150054
increased circulating interleukin-1 beta level J:150054
increased circulating interleukin-6 level J:150054
increased circulating interleukin-18 level J:150054
increased circulating tumor necrosis factor level J:150054
increased inflammatory response J:150054
increased leukocyte cell number J:150054
increased neutrophil cell number J:150054
Nlrp3tm1Hhf/Nlrp3+
Rag1tm1Mom/Rag1tm1Mom
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
absent B cells J:150054
absent T cells J:150054
Nlrp3tm1Hhf/Nlrp3+
Tg(CAG-cre/Esr1*)5Amc/?

(involves: 129/Sv * C57BL/6 * CBA)
skin inflammation J:150054
Nlrp3tm1Hhf/Nlrp3+
Tg(CAG-cre/Esr1*)5Amc/?

(involves: 129/Sv * C57BL/6 * CBA)
abnormal dendritic cell antigen presentation J:150054
abnormal dendritic cell physiology J:150054
abnormal macrophage physiology J:150054
Nlrp3tm1Hhf/Nlrp3+
Tg(Zp3-cre)3Mrt/?

(involves: 129/Sv * FVB/N)
increased inflammatory response J:150054
increased leukocyte cell number J:150054
increased neutrophil cell number J:150054
Nlrp3tm1Tsc/Nlrp3tm1Tsc
(C57BL/6-Nlrp3tm1Tsc)
decreased interleukin-1 beta secretion J:124226
Nlrp3tm1Tsc/Nlrp3tm1Tsc
(involves: C57BL/6)
decreased interleukin-1 beta secretion J:172117
Nlrp3tm1Vmd/Nlrp3tm1Vmd
(involves: C57BL/6N)
abnormal cytokine secretion J:106976
abnormal response to infection J:106976
decreased susceptibility to endotoxin shock J:106976
Nlrp3tm1Vmd/Nlrp3tm1Vmd
(B6.B6N-Nlrp3tm1Vmd)
decreased circulating interleukin-1 beta level J:193522
decreased circulating interleukin-18 level J:193522
decreased interleukin-1 beta secretion J:193522
decreased susceptibility to endotoxin shock J:193522
immune system phenotype J:294930
Nlrp3tm1Wstr/Nlrp3+
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell number J:150053
abnormal dendritic cell physiology J:150053
abnormal lymph node morphology J:150053
abnormal macrophage physiology J:150053
abnormal spleen red pulp morphology J:150053
chronic inflammation J:150053
dermatitis J:150053
enlarged lymph nodes J:150053
enlarged spleen J:150053
increased activated T cell number J:150053
increased anti-double stranded DNA antibody level J:150053
increased interleukin-1 beta secretion J:150053
increased interleukin-17 secretion J:150053
increased interleukin-18 secretion J:150053
increased leukocyte cell number J:150053
increased susceptibility to type IV hypersensitivity reaction J:150053
increased T-helper 1 cell number J:150053
Nlrp3tm2Hhf/Nlrp3+
Tg(CAG-cre/Esr1*)5Amc/?

(involves: 129/Sv * C57BL/6 * CBA)
skin inflammation J:150054
Nlrp3tm2Hhf/Nlrp3+
Tg(CAG-cre/Esr1*)5Amc/?

(involves: 129/Sv * C57BL/6 * CBA)
abnormal dendritic cell physiology J:150054
abnormal macrophage physiology J:150054
Nlrp3tm2Hhf/Nlrp3tm2Hhf
Vsig4tm1Gne/Vsig4tm1Gne

(B6.Cg-Nlrp3tm2Hhf Vsig4tm1Gne)
decreased susceptibility to experimental autoimmune encephalomyelitis J:281762
Nlrp3tm3.1Hhf/Nlrp3+
(involves: 129)
abnormal circulating chemokine level J:202147
abnormal osteoclast differentiation J:202147
decreased circulating interleukin-5 level J:202147
decreased circulating interleukin-12b level J:202147
decreased lymphocyte cell number J:202147
immune system phenotype J:202147
increased circulating interleukin-1 beta level J:202147
increased circulating interleukin-3 level J:202147
increased circulating interleukin-4 level J:202147
increased circulating interleukin-6 level J:202147
increased circulating interleukin-9 level J:202147
increased circulating interleukin-13 level J:202147
increased circulating interleukin-18 level J:202147
increased circulating tumor necrosis factor level J:202147
increased granulocyte number J:202147
increased inflammatory response J:202147
increased interferon-gamma secretion J:202147
increased interleukin-1 beta secretion J:202147
increased lymphocyte cell number J:202147
increased monocyte cell number J:202147
increased neutrophil cell number J:202147
increased osteoclast cell number J:202147
joint inflammation J:202147
meningitis J:202147
osteomyelitis J:202147
Nlrp6tm1Flv/Nlrp6tm1Flv
(B6.Cg-Nlrp6tm1Flv)
decreased circulating interleukin-18 level J:173245
decreased interleukin-18 secretion J:173245
enlarged Peyer's patches J:173245
increased B cell number J:173245
increased IgA level J:173245
increased IgG2c level J:173245
increased leukocyte cell number J:173245
increased susceptibility to induced colitis J:173245
increased susceptibility to Riboviria infection induced morbidity/mortality J:243487
Nlrp6tm1Macha/Nlrp6tm1Macha
(involves: 129S5/SvEvBrd * C57BL/6J)
increased susceptibility to induced colitis J:173352
Nlrp9bem1Flv/Nlrp9bem1Flv
(C57BL/6N-Nlrp9bem1Flv)
increased susceptibility to Riboviria infection induced morbidity/mortality J:243487
Nlrp9btm1b(KOMP)Wtsi/Nlrp9btm1b(KOMP)Wtsi
(C57BL/6N-Nlrp9btm1b(KOMP)Wtsi/H)
enlarged spleen J:211773
Nlrp10tm1Seis/Nlrp10tm1Seis
(involves: C57BL/6)
immune system phenotype J:173245
Nlrp10tm1Seis/Nlrp10tm1Seis
(B6.Cg-Nlrp10tm1Seis)
abnormal adaptive immunity J:183989
abnormal dendritic cell physiology J:183989
abnormal T-helper 2 physiology J:183989
decreased dendritic cell number J:183989
decreased IgG1 level J:183989
decreased interferon-gamma secretion J:183989
decreased interleukin-17 secretion J:183989
decreased susceptibility to endotoxin shock J:183989
decreased susceptibility to experimental autoimmune encephalomyelitis J:183989
Nlrp12tm1Jpyt/Nlrp12tm1Jpyt
(B6.Cg-Nlrp12tm1Jpyt)
abnormal leukocyte migration J:164725
decreased neutrophil cell number J:164725
decreased susceptibility to type IV hypersensitivity reaction J:164725
impaired neutrophil chemotaxis J:164725
Nlrp12tm1Jpyt/Nlrp12tm1Jpyt
(Not Specified)
immune system phenotype J:173245
Nlrp12tm1Tdk/Nlrp12tm1Tdk
(B6.Cg-Nlrp12tm1Tdk)
abnormal chemokine level J:178951
abnormal cytokine level J:178951
enlarged spleen J:178951
increased inflammatory response J:178951
increased susceptibility to induced colitis J:178951
Nlrx1em1(IMPC)Mbp/Nlrx1em1(IMPC)Mbp
(C57BL/6N-Nlrx1em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Nlrx1tm1Jpyt/Nlrx1tm1Jpyt
(involves: C57BL/6 * C57BL/6J)
abnormal macrophage physiology J:173995
abnormal neutrophil physiology J:173995
increased circulating interleukin-6 level J:173995
increased interferon-beta secretion J:173995
increased interleukin-1 beta secretion J:173995
increased interleukin-6 secretion J:173995
increased susceptibility to endotoxin shock J:173995
increased susceptibility to Orthomyxoviridae infection J:173995
Nme2Gt(69C10)Cmhd/Nme2Gt(69C10)Cmhd
(B6.129-Nme2Gt(69C10)Cmhd)
abnormal CD4-positive, alpha-beta T cell physiology J:167387
abnormal T-helper 1 physiology J:167387
abnormal T-helper 2 physiology J:167387
decreased interferon-gamma secretion J:167387
decreased interleukin-2 secretion J:167387
decreased interleukin-13 secretion J:167387
decreased tumor necrosis factor secretion J:167387
immune system phenotype J:167387
Nme5tm1Lex/Nme5tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
maxillary sinus inflammation J:185566
nasal inflammation J:185566
nmf4/nmf4
(C57BL/6J-nmf4/J)
small spleen J:78134
thymus cortex atrophy J:78134
nmf356/nmf356
(C57BL/6J-nmf356/J)
thymus atrophy J:87349
nmf370/nmf370
(C57BL/6J-nmf370/J)
ear inflammation J:87349
nmf391/nmf391
(C57BL/6J-nmf391/J)
ear inflammation J:87349
Nmiem1Hhl/Nmiem1Hhl
(C57BL/6-Nmiem1Hhl)
decreased circulating interleukin-6 level J:298909
decreased circulating tumor necrosis factor level J:298909
decreased susceptibility to bacterial infection induced morbidity/mortality J:298909
decreased susceptibility to endotoxin shock J:298909
Nmnat2em1(IMPC)Mbp/Nmnat2+
(C57BL/6N-Nmnat2em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Nmnat3Gt(3020)Tgen/Nmnat3Gt(3020)Tgen
(involves: C57BL/6NCrlj * CBA/JNCrlj)
enlarged spleen J:214107
increased spleen iron level J:214107
increased spleen red pulp amount J:214107
increased spleen weight J:214107
Nmt1tm1.1Poru/Nmt1tm1.1Poru
Nmt2tm1.1Poru/Nmt2tm1.1Poru
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal CD4-positive, alpha beta T cell morphology J:226234
abnormal CD8-positive, alpha beta T cell morphology J:226234
decreased circulating interferon-gamma level J:226234
decreased circulating interleukin-2 level J:226234
decreased circulating tumor necrosis factor level J:226234
decreased DN4 thymocyte number J:226234
decreased double-positive T cell number J:226234
decreased interferon-gamma secretion J:226234
decreased interleukin-2 secretion J:226234
decreased single-positive T cell number J:226234
decreased splenocyte proliferation J:226234
decreased susceptibility to endotoxin shock J:226234
decreased T cell number J:226234
decreased T cell proliferation J:226234
immune system phenotype J:226234
increased double-negative T cell number J:226234
increased gamma-delta T cell number J:226234
increased T cell apoptosis J:226234
small thymus medulla J:226234
Nmt1tm1.1Poru/Nmt1tm1.1Poru
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal CD4-positive, alpha beta T cell morphology J:226234
abnormal CD8-positive, alpha beta T cell morphology J:226234
decreased double-positive T cell number J:226234
decreased single-positive T cell number J:226234
decreased T cell number J:226234
Nmt2tm1.1Poru/Nmt2tm1.1Poru
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
decreased double-positive T cell number J:226234
decreased single-positive T cell number J:226234
decreased T cell number J:226234
Nmutm1Sjab/Nmutm1Sjab
(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating interleukin-6 level J:142907
Nnatem1(IMPC)Mbp/Nnatem1(IMPC)Mbp
(C57BL/6NCrl-Nnatem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Nnmtem1(IMPC)Mbp/Nnmtem1(IMPC)Mbp
(C57BL/6NCrl-Nnmtem1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Noa/Noa+
(NOA)
cutaneous mastocytosis J:43274
increased IgE level J:43274
Noc2ltm1.1Arte/Noc2ltm1.1Arte
Tg(CD2-icre)4Kio/0

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
abnormal B cell morphology J:216490
abnormal T cell morphology J:216490
abnormal T cell proliferation J:216490
abnormal thymus cell ratio J:216490
abnormal thymus involution J:216490
abnormal thymus morphology J:216490
absent T cells J:216490
arrested T cell differentiation J:216490
decreased alpha-beta T cell number J:216490
decreased DN3 thymocyte number J:216490
decreased DN4 thymocyte number J:216490
decreased double-positive T cell number J:216490
decreased immature B cell number J:216490
decreased mature B cell number J:216490
decreased pre-B cell number J:216490
decreased pro-B cell number J:216490
decreased single-positive T cell number J:216490
increased thymocyte apoptosis J:216490
small thymus J:216490
spleen hypoplasia J:216490
thymus hypoplasia J:216490
Noc2ltm1.1Arte/Noc2ltm1.1Arte
Trp53tm1Brn/Trp53tm1Brn
Tg(CD2-icre)4Kio/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * CBA/Ca)
decreased pre-B cell number J:216490
Nod1tm1Bert/Nod1tm1Bert
(involves: C57BL/6)
immune system phenotype J:117688
Nod1tm1Inoh/Nod1tm1Inoh
(involves: 129P2/OlaHsd * C57BL/6)
abnormal chemokine secretion J:118808
abnormal cytokine secretion J:118808
abnormal immune system physiology J:118808
abnormal macrophage physiology J:132126, J:118808
decreased interleukin-6 secretion J:132126
decreased tumor necrosis factor secretion J:132126
Nod1tm1Inoh/Nod1tm1Inoh
Nod2tm1Flv/Nod2tm1Flv

(involves: 129 * 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:132126
decreased interleukin-6 secretion J:132126
decreased tumor necrosis factor secretion J:132126
increased susceptibility to bacterial infection J:132126
Nod2em1(IMPC)Mbp/Nod2em1(IMPC)Mbp
(C57BL/6N-Nod2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Nod2tm1Daph/Nod2tm1Daph
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal macrophage physiology J:157879
Nod2tm1Flv/Nod2tm1Flv
(involves: 129S1/Sv * C57BL/6)
abnormal macrophage physiology J:132126, J:96035
abnormal susceptibility to infection J:96035
decreased IgG level J:96035
decreased interleukin-6 secretion J:132126
decreased susceptibility to endotoxin shock J:96035
decreased tumor necrosis factor secretion J:132126
Nod2tm1Flv/Nod2tm1Flv
(involves: 129S1/Sv)
abnormal response to infection J:147177
abnormal T-helper 1 physiology J:147177
impaired macrophage phagocytosis J:147177
impaired neutrophil phagocytosis J:147177
increased circulating interferon-gamma level J:147177
increased circulating interleukin-2 level J:147177
increased circulating tumor necrosis factor level J:147177
increased leukocyte cell number J:147177
increased neutrophil cell number J:147177
increased susceptibility to bacterial infection induced morbidity/mortality J:147177
Nod2tm1Flv/Nod2tm1Flv
(C.129S1-Nod2tm1Flv)
decreased susceptibility to induced arthritis J:178054
Nod2tm1Jhgt/Nod2tm1Jhgt
(B6.Cg-Nod2tm1Jhgt)
abnormal cytokine level J:124575
abnormal immune system morphology J:124575
abnormal immune system physiology J:124575
abnormal interferon level J:124575
abnormal interleukin level J:124575
abnormal lymph node B cell domain morphology J:124575
abnormal Peyer's patch morphology J:124575
abnormal response to infection J:124575
abnormal tumor necrosis factor level J:124575
enlarged Peyer's patches J:124575
increased CD4-positive, alpha-beta T cell number J:124575
increased double-negative T cell number J:124575
increased Peyer's patch number J:124575
increased susceptibility to induced colitis J:124575
Nod2tm1Mka/Nod2tm1Mka
(involves: C57BL/6)
abnormal cytokine level J:96128
abnormal macrophage morphology J:96128
increased interleukin-1 beta secretion J:96128
increased susceptibility to induced colitis J:96128
Nod2tm1Pmu/Nod2tm1Pmu
(involves: BALB/c * C57BL/6)
abnormal macrophage physiology J:86264
decreased susceptibility to endotoxin shock J:86264
Nod2tm1Vmd/Nod2tm1Vmd
(B6.129-Nod2tm1Vmd)
abnormal cytokine secretion J:106976
Nodaltm1.1Mku/Nodaltm2Mku
Tg(T-cre)1Lwd/0

(involves: 129S1/Sv * C3H * C57BL/6)
absent spleen J:142430
small spleen J:142430
Nodaltm1.2Rob/Nodaltm3Rob
(involves: 129S/SvEv * MF1)
small spleen J:79098
Nodaltm1b(EUCOMM)Wtsi/Nodal+
(C57BL/6N-Nodaltm1b(EUCOMM)Wtsi/H)
increased large unstained cell number J:211773
Nodaltm1Hmd/Nodal+
Tg(Rr443-Lefty1,-lacZ)36Hmd/0

(either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6N) or (involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ))
small spleen J:82703
Nodaltm1Hmd/Nodaltm1Hmd
(either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6N) or (involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ))
abnormal spleen morphology J:82703
spleen hypoplasia J:82703
Nol3em1(IMPC)Mbp/Nol3em1(IMPC)Mbp
(C57BL/6N-Nol3em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
small spleen J:211773
Nop53tm2.1Asuz/Nop53tm2.1Asuz
Tg(Lck-cre)#Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
decreased thymocyte number J:241062
Nop53tm2.1Asuz/Nop53tm2.1Asuz
Trp53tm1Tyj/Trp53tm1Tyj
Tg(Lck-cre)#Jxm/0

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * CBA)
decreased thymocyte number J:241062
Nos1tm1Plh/Nos1tm1Plh
(involves: 129S4/SvJae)
abnormal leukocyte adhesion J:55936
abnormal neutrophil physiology J:55936
enhanced leukocyte tethering or rolling J:55936
Nos1tm1Plh/Nos1tm1Plh
(B6;129S4-Nos1tm1Plh/J)
abnormal osteoclast differentiation J:105612
Nos1tm1Plh/Nos1tm1Plh
(B6.129S4-Nos1tm1Plh/J)
decreased inflammatory response J:103018
Nos1tm1Plh/Nos1tm1Plh
Nos2tm1Mrl/Nos2tm1Mrl
Nos3tm1Plh/Nos3tm1Plh

(involves: 129S4/SvJae * 129S7/SvEvBrd)
abnormal osteoclast physiology J:150159
increased osteoclast cell number J:150159
Nos2tm1Lau/Nos2tm1Lau
(involves: 129P2/OlaHsd * C57BL/6)
abnormal adaptive immunity J:90903
abnormal immune system morphology J:90903
enlarged inguinal lymph nodes J:90903
immune system phenotype J:64036, J:29677
increased single-positive T cell number J:90903
increased susceptibility to bacterial infection J:100513
increased T cell proliferation J:90903
skin inflammation J:64036
Nos2tm1Lau/Nos2tm1Lau
(B6.129P2-Nos2tm1Lau)
abnormal osteoclast morphology J:112399
decreased susceptibility to induced colitis J:87601
Nos2tm1Lau/Nos2tm1Lau
(B6.129P2-Nos2tm1Lau/J)
abnormal inflammatory response J:103018
decreased inflammatory response J:103018
Nos2tm1Lau/Nos2tm1Lau
(involves: 129P2/OlaHsd)
immune system phenotype J:55936
Nos2tm1Liew/Nos2tm1Liew
(involves: 129P2/Ola * MF1)
abnormal T-helper 1 physiology J:25755
decreased inflammatory response J:25755
decreased susceptibility to endotoxin shock J:25755
increased interferon-gamma secretion J:25755
increased susceptibility to parasitic infection J:25755
increased T cell proliferation J:25755
Nos2tm1Liew/Nos2tm1Liew
(involves: 129 * 129P2/OlaHsd)
immune system phenotype J:118561
Nos2tm1Mrl/Nos2tm1Mrl
(involves: 129S7/SvEvBrd)
abnormal eosinophil cell number J:51635
abnormal immune system physiology J:51635
abnormal macrophage physiology J:120499
decreased eosinophil cell number J:51635
decreased susceptibility to endotoxin shock J:25511
increased IgG2a level J:51635
increased inflammatory response J:51635
increased interferon-gamma secretion J:51635
increased susceptibility to bacterial infection J:25511
Nos2tm1Mrl/Nos2tm1Mrl
(involves: 129S7/SvEvBrd * C57BL/6)
increased length of allograft survival J:54764
pancreas inflammation J:65562
Nos2tm1Mrl/Nos2tm1Mrl
(B6.129S7-Nos2tm1Mrl)
abnormal osteoclast differentiation J:98070
abnormal osteoclast morphology J:98070
abnormal response to infection J:98070
decreased osteoclast cell number J:98070
Nos2tm1Mrl/Nos2tm1Mrl
(involves: 129S7/SvEvBrd * PL/J)
increased susceptibility to experimental autoimmune encephalomyelitis J:46192
Nos3em1(IMPC)Mbp/Nos3em1(IMPC)Mbp
(C57BL/6N-Nos3em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
Nos3m1Btlr/Nos3m1Btlr
(C57BL/6J-Nos3m1Btlr)
increased susceptibility to induced colitis J:225268
Nos3M2Btlr/Nos3M2Btlr
(C57BL/6J-Nos3M2Btlr)
increased susceptibility to induced colitis J:272392
Nos3tm1Plh/Nos3tm1Plh
(involves: 129S4/SvJae)
abnormal leukocyte adhesion J:55936
abnormal neutrophil physiology J:55936
enhanced leukocyte tethering or rolling J:55936
Nos3tm1Plh/Nos3tm1Plh
(involves: 129S4/SvJae * C57BL/6)
increased susceptibility to bacterial infection J:105005
increased susceptibility to bacterial infection induced morbidity/mortality J:105005
Nos3tm1Unc/Nos3tm1Unc
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:36559
Nos3tm1Unc/Nos3tm1Unc
(B6.129P2-Nos3tm1Unc/J)
abnormal osteoclast physiology J:129477
increased inflammatory response J:103018
kidney inflammation J:148626
Notch1tm1Agt/Notch1tm1Agt
Notch2tm1Frad/Notch2tm1Frad
Tg(Mx1-cre)1Cgn/0

(involves: 129 * BALB/c * C57BL/6 * CBA)
abnormal T cell differentiation J:125373
arrested T cell differentiation J:125373
Notch1tm1Agt/Notch1tm1Agt
Notch2tm3Grid/Notch2tm3Grid
Tg(TcrAND)53Hed/?

(involves: 129/Sv * 129S1/Sv * C57BL/6 * SJL)
abnormal humoral immune response J:123631
abnormal response to infection J:123631
decreased interleukin-4 secretion J:123631
Notch1tm1Agt/Notch1tm1Agt
Tg(Mx1-cre)1Cgn/0

(involves: 129 * C57BL/6 * CBA)
abnormal B cell differentiation J:125373
abnormal T cell differentiation J:125373, J:55400
abnormal thymus cell ratio J:55400, J:143472
abnormal thymus morphology J:55400
decreased CD4-positive, alpha-beta T cell number J:55400
decreased CD8-positive, alpha-beta T cell number J:55400
decreased double-negative T cell number J:55400
decreased double-positive T cell number J:55400
decreased single-positive T cell number J:55400
decreased thymocyte number J:55400
increased immature B cell number J:143472
small thymus J:55400
Notch1tm1Con/Notch1+
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
aortic valve inflammation J:187551
Notch1tm2Pst/Notch1tm2Pst
(B6.Cg-Notch1tm2Pst)
abnormal T cell differentiation J:131563
decreased double-negative T cell number J:131563
decreased T cell number J:131563
decreased thymocyte number J:131563
increased T cell apoptosis J:131563
Notch1tm2Rko/Notch1tm2Rko
Notch2tm1Rko/Notch2tm1Rko
Notch3Gt(PST033)Byg/Notch3+
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA)
abnormal spleen morphology J:172442
enlarged spleen J:172442
increased spleen red pulp amount J:172442
Notch1tm2Rko/Notch1tm2Rko
Notch2tm1Rko/Notch2tm1Rko
Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA)
abnormal spleen morphology J:172442
enlarged spleen J:172442
increased spleen red pulp amount J:172442
Notch1tm2Rko/Notch1tm3(cre)Rko
(involves: 129X1/SvJ * C57BL/6)
abnormal spleen morphology J:171829
chronic liver inflammation J:171829
enlarged spleen J:171829
Notch2Gt(betageo)1Byg/Notch2+
(B6.129P2-Notch2Gt(betageo)1Byg)
decreased marginal zone B cell number J:146621
Notch2tm1.1Ecan/Notch2+
(involves: 129 * 129S1/Sv * C57BL/6J)
abnormal osteoclast differentiation J:230045
abnormal osteoclast morphology J:230045
increased osteoclast cell number J:230045
Notch2tm1.1Hhi/Notch2tm1.1Hhi
Tg(Cd8a-cre)1Itan/0

(involves: C57BL/6 * CBA)
abnormal CD8-positive, alpha-beta T cell physiology J:141009
abnormal cytotoxic T cell physiology J:141009
increased susceptibility to parasitic infection J:141009
Notch2tm1.1Hhtg/Notch2+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal interleukin level J:311038
abnormal osteoclast differentiation J:311038
increased circulating interleukin-6 level J:311038
increased interleukin-6 secretion J:311038
increased osteoclast cell number J:311038
Notch2tm1Frad/Notch2tm1Frad
Tg(Mx1-cre)1Cgn/0

(involves: BALB/c * C57BL/6 * CBA)
abnormal B cell differentiation J:125373
absent marginal zone B cells J:125373
Notch2tm1Yha/Notch2+
(B6.129-Notch2tm1Yha)
abnormal spleen marginal zone morphology J:85379
decreased B-1 B cell number J:85379
decreased marginal zone B cell number J:85379
Notch2tm2.1Ecan/Notch2tm2.1Ecan
Tg(BGLAP-cre)1Clem/0

(involves: C57BL/6J * FVB/NJ)
increased osteoclast cell number J:246017
Notch2tm2Hhi/Notch2tm1.1Hhi
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
decreased marginal zone B cell number J:83476
immune system phenotype J:83476
Notch3em1Ecan/Notch3+
(C57BL/6J-Notch3em1Ecan)
abnormal osteoclast differentiation J:270682
increased osteoclast cell number J:270682
Notch3tm1.1(KOMP)Vlcg/Notch3tm1.1(KOMP)Vlcg
(C57BL/6N-Notch3tm1.1(KOMP)Vlcg/Ucd)
increased neutrophil cell number J:211773
increased spleen weight J:211773
Notch3tm1Khan/Notch3tm1Khan
(involves: C57BL/6 * CBA)
decreased thymocyte number J:98284
small thymus J:98284
Notumem1(IMPC)Tcp/Notum+
(C57BL/6NCrl-Notumem1(IMPC)Tcp/Tcp)
small spleen J:211773
NotumGt(OST172035)Lex/NotumGt(OST172035)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
chronic inflammation J:274615
increased leukocyte cell number J:274615
periodontium inflammation J:266040
Nox1tm1.1Anrt/Nox1tm1.1Anrt
Tg(Vil1-cre)997Gum/0

(involves: C57BL/6J * SJL)
colitis J:194294
Nox1tm1Cyn/Y
(involves: 129S1/Sv * 129X1/SvJ)
abnormal cytokine secretion J:218649
Nox4em1(IMPC)Mbp/Nox4em1(IMPC)Mbp
(C57BL/6N-Nox4em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Nox4tm1Syb/Nox4tm1Syb
(involves: 129S4/SvJae)
decreased interleukin-1 beta secretion J:298830
decreased susceptibility to endotoxin shock J:298830
decreased tumor necrosis factor secretion J:298830
Npas2em1(IMPC)Mbp/Npas2em1(IMPC)Mbp
(C57BL/6N-Npas2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased neutrophil cell number J:211773
Npas3tm1Mesu/Npas3tm1Mesu
(B6.129S6-Npas3tm1Mesu)
bronchiectasis J:150793
Npas4em1(IMPC)H/Npas4em1(IMPC)H
(C57BL/6NTac-Npas4em1(IMPC)H/H)
abnormal thymus morphology J:211773
Npattm1b(EUCOMM)Wtsi/Npattm1b(EUCOMM)Wtsi
(C57BL/6N-Npattm1b(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Npc1m1N/Npc1m1N
(involves: BALB/c)
abnormal alveolar macrophage morphology J:204311
enlarged spleen J:76733
Npc1m1N/Npc1m1N
(BALB/cNctr-Npc1m1N/J)
enlarged spleen J:179744
microgliosis J:209834
nasal inflammation J:209834
Npc1m1N/Npc1m1N
(involves: BALB/c * C57BL/6 * CBA)
abnormal microglial cell physiology J:144240
Npc1m1N/Npc1m1N
(B6.C-Npc1m1N)
microgliosis J:157113
Npc1m1N/Npc1m1N
(BALB/c-Npc1m1N)
abnormal macrophage morphology J:221855
abnormal microglial cell activation J:221855
increased macrophage derived foam cell number J:221855
increased microglial cell activation J:221855
Npc1m1N/Npc1m1N
(involves: BALB/c * C3H/HeJ * C57BL/6J)
microgliosis J:188345
Npc1m1N/Npc1m1N
Tg(PRNP-APPSweInd)8Dwst/0

(involves: BALB/c * C3H/HeJ * C57BL/6J)
microgliosis J:188345
Npc1m1N/Npc1m1N
Tlr4tm1Aki/Tlr4tm1Aki

(involves: 129P2/OlaHsd * BALB/c)
abnormal cytokine secretion J:118352
Npc1m1N/Npc1tm1.1Apl
Tg(CAG-cre/Esr1*)5Amc/0

(B6J.Cg-Npc1m1N/Npc1tm1.1Apl Tg(CAG-cre/Esr1*)5Amc)
microgliosis J:176888
Npc1m1N/Npc1tm1.1Apl
Tg(Syn1-cre)671Jxm/0

(B6J.Cg-Npc1m1N/Npc1tm1.1Apl Tg(Syn1-cre)671Jxm)
microgliosis J:176888
Npc1m1N/Npc1tm1.2Apl
(B6.Cg-Npc1m1N/Npc1tm1.2Apl)
microgliosis J:157113
Npc1nmf164/Npc1nmf164
(C57BL/6J-Npc1nmf164/J)
enlarged spleen J:179744
increased macrophage derived foam cell number J:179744
increased microglial cell activation J:179744
Npc1spm/Npc1spm
(C57BLKS/J-Npc1spm/J)
enlarged spleen J:7245
increased macrophage derived foam cell number J:7245
Npc1tm1.1Apl/Npc1tm1.2Apl
Tg(Pcp2-cre)2Mpin/0

(B6.Cg-Npc1tm1.1Apl/Npc1tm1.2Apl Tg(Pcp2-cre)2Mpin)
microgliosis J:157113
Npc1tm1.1Dso/Npc1tm1.1Dso
(B6.129-Npc1tm1.1Dso)
abnormal macrophage morphology J:221855
abnormal microglial cell activation J:221855
increased macrophage cell number J:221855
increased macrophage derived foam cell number J:221855
increased microglial cell activation J:221855
microgliosis J:221855
Npc2Gt(LST105)Byg/Npc2Gt(LST105)Byg
(B6.129P2-Npc2Gt(LST105)Byg)
abnormal immune system morphology J:125609
abnormal immune system physiology J:125609
Npc2tm1Plob/Npc2tm1Plob
(involves: 129S1/Sv * C57BL/6)
decreased NK cell number J:125609
Npc2tm1Plob/Npc2tm1Plob
(C.129S1-Npc2tm1Plob)
abnormal NK cell physiology J:125609
abnormal T cell physiology J:125609
decreased NK cell number J:125609
Npc2tm1Plob/Npc2tm1Plob
(involves: 129S1/Sv * BALB/c)
abnormal alveolar macrophage morphology J:204311
Npeppstm1Klr/Npeppstm1Klr
(involves: 129 * C57BL/6)
immune system phenotype J:131502
Npffr2tm1.2Ics/Npffr2tm1.2Ics
(involves: C57BL/6N)
abnormal macrophage activation involved in immune response J:245025
decreased macrophage cell number J:245025
decreased macrophage proliferation J:245025
Nphp3pcy/Nphp3pcy
(KK-Nphp3pcy)
kidney inflammation J:8302
Nphp3pcy/Nphp3pcy
(either: D2.KK-Nphp3pcy or (involves: DBA/2Fg * DBA/2J * KK))
kidney inflammation J:11399
Nphp3pol/Nphp3pol
(C57BL/6JSfdAnu-Nphp3pol/Anu)
kidney inflammation J:104190
NplGt(OST15553)Lex/NplGt(OST15553)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
immune system phenotype J:103485
Npm1tm1Gsva/Npm1+
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
decreased B cell number J:172071
enlarged spleen J:172071
increased granulocyte number J:172071
increased leukocyte cell number J:172071
increased spleen weight J:172071
Npm1tm1Hft/Npm1+
(involves: 129)
abnormal granulocyte differentiation J:194999
abnormal spleen B cell follicle morphology J:194999
enlarged spleen J:194999
increased granulocyte number J:194999
increased leukocyte cell number J:194999
increased monocyte cell number J:194999
increased spleen weight J:194999
myeloid hyperplasia J:194999
Npm1tm1Ppp/Npm1+
(involves: 129S1/Sv * C57BL/6)
abnormal thrombopoiesis J:101494
Npr1tm1Gar/Npr1tm1Gar
(B6.129S7-Npr1tm1Gar)
impaired neutrophil chemotaxis J:70496
Npr2cn/Npr2cn
(AKR/J)
small spleen J:5109
Npr3tm1Unc/Npr3tm1Unc
(involves: 129 * C57BL/6)
abnormal osteoclast morphology J:56058
Nprl3tm1.1Drhi/Nprl3tm1.1Drhi
(involves: 129P2/OlaHsd)
abnormal lymph organ development J:183988
Npsr1tm1b(KOMP)Wtsi/Npsr1tm1b(KOMP)Wtsi
(C57BL/6N-Npsr1tm1b(KOMP)Wtsi/Rbrc)
increased eosinophil cell number J:211773
Npsr1tm1Bhk/Npsr1tm1Bhk
(either: (involves: 129S6/SvEvTac * BALB/c) or (involves: 129S6/SvEvTac * C57BL/6))
immune system phenotype J:144688
Npsr1tm1Bhk/Npsr1tm1Bhk
(129S/SvEv-Npsr1tm1Bhk)
immune system phenotype J:144688
Npy1rtm1.1Wpg/Npy1rtm1.1Wpg
(involves: 129X1/SvJ * C57BL/6)
abnormal immune cell physiology J:118850
abnormal immune system organ morphology J:118850
abnormal immune system physiology J:118850
abnormal immunoglobulin level J:118850
abnormal inflammatory response J:118850
abnormal lymph node cell ratio J:118850
abnormal macrophage physiology J:118850
abnormal professional antigen presenting cell physiology J:118850
abnormal spleen morphology J:118850
abnormal splenic cell ratio J:118850
abnormal T cell activation J:118850
abnormal T cell number J:118850
abnormal T-helper 1 physiology J:118850
decreased B cell number J:118850
decreased CD8-positive, alpha-beta T cell number J:118850
decreased circulating interleukin-12 level J:118850
decreased circulating tumor necrosis factor level J:118850
decreased IgG2a level J:118850
decreased interferon-gamma secretion J:118850
decreased marginal zone B cell number J:118850
decreased mature B cell number J:118850
decreased susceptibility to type IV hypersensitivity reaction J:118850
decreased transitional stage B cell number J:118850
increased CD4-positive, alpha-beta T cell number J:118850
increased CD8-positive, alpha-beta T cell number J:118850
increased IgA level J:118850
increased IgG2b level J:118850
increased IgM level J:118850
increased immunoglobulin level J:118850
increased single-positive T cell number J:118850
small spleen J:118850
Npy2rem1(IMPC)H/Npy2rem1(IMPC)H
(C57BL/6N-Npy2rem1(IMPC)H/H)
enlarged spleen J:211773
increased spleen weight J:211773
Npy2rtm1.1Hhz/Npy2rtm1.1Hhz
(involves: 129X1/SvJ * BALB/cJ * C57BL/6)
decreased osteoclast cell number J:84570
Npy2rtm1Hhz/Npy2rtm1Hhz
(involves: 129X1/SvJ * C57BL/6)
decreased osteoclast cell number J:97455
Nqo2tm1Akj/Nqo2tm1Akj
(Not Specified)
abnormal lymphopoiesis J:80549
increased granulocyte number J:80549
Nr1d1tm1(KOMP)Vlcg/Nr1d1tm1(KOMP)Vlcg
(C57BL/6N-Nr1d1tm1(KOMP)Vlcg/Bay)
decreased NK cell number J:211773
Nr1h2tm1.1Gstr/Nr1h2tm1.1Gstr
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
increased microglial cell activation J:278794
Nr1h2tm1.1Gstr/Nr1h2tm1.1Gstr
Nr1h3tm1.1Gstr/Nr1h3tm1.1Gstr

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
increased macrophage derived foam cell number J:81790, J:234268
lung inflammation J:234268
Nr1h2tm1Djm/Nr1h2tm1Djm
(involves: 129S6/SvEvTac * C57BL/6)
increased susceptibility to bacterial infection J:81696
Nr1h2tm1Djm/Nr1h2tm1Djm
Nr1h3tm1Djm/Nr1h3tm1Djm

(involves: 129S6/SvEvTac * C57BL/6)
abnormal macrophage morphology J:125452
increased susceptibility to bacterial infection J:81696
Nr1h3tm1Djm/Nr1h3tm1Djm
(involves: 129S6/SvEvTac * C57BL/6)
increased inflammatory response J:158168
increased susceptibility to bacterial infection J:81696
Nr1h3tm1Wexi/Nr1h3tm1Wexi
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
decreased susceptibility to endotoxin shock J:155709
Nr1h4tm1.1Mbj/Nr1h4tm1.1Mbj
(B6N.B6-Nr1h4tm1.1Mbj)
increased spleen weight J:200842
liver inflammation J:200842
Nr1h4tm1Gonz/Nr1h4tm1Gonz
(involves: 129X1/SvJ * C57BL/6)
liver inflammation J:118204
Nr2c2tm1Amj/Nr2c2tm1Amj
(B6.129-Nr2c2tm1Amj)
decreased inflammatory response J:169333
Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa
Rbpjtm1Hon/Rbpjtm1Hon
Tg(Tek-cre)1Ywa/0

(involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * SJL)
decreased lymphatic vessel endothelial cell number J:158959
Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa
Tg(Tek-cre)1Ywa/0

(involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * SJL)
decreased lymphatic vessel endothelial cell number J:158959
Nr3c1tm1.1Jaci/Nr3c1tm1.1Jaci
Tg(Myh6-cre)2182Mds/0

(involves: C57BL/6 * FVB/N)
heart inflammation J:201995
Nr3c1tm1.1Jda/Nr3c1+
Tg(Lck-cre)548Jxm/0

(B6.Cg-Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm)
decreased thymocyte apoptosis J:189951
Nr3c1tm1.1Jda/Nr3c1tm1.1Jda
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Tg(Lck-cre)548Jxm/0
Tg(TcrAND)53Hed/0

(B6.Cg-Rag2tm1.1Cgn Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm Tg(TcrAND)53Hed)
decreased double-positive T cell number J:189951
Nr3c1tm1.1Jda/Nr3c1tm1.1Jda
Tcratm1Mom/Tcratm1Mom
Tg(Lck-cre)548Jxm/0

(B6.Cg-Tcratm1Mom Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm)
decreased double-positive T cell number J:189951
Nr3c1tm1.1Jda/Nr3c1tm1.1Jda
Tg(Lck-cre)548Jxm/0

(B6.Cg-Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm)
abnormal humoral immune response J:189951
decreased CD4-positive, alpha-beta T cell number J:189951
decreased CD8-positive, alpha-beta T cell number J:189951
decreased double-positive T cell number J:189951
decreased single-positive T cell number J:189951
decreased thymocyte apoptosis J:189951
thymus hypoplasia J:189951
Nr3c1tm1Dage/Nr3c1+
(involves: 129P1/ReJ * C57BL/6 * C57BL/6J * SJL)
decreased B cell number J:147914
Nr3c1tm1Dage/Nr3c1tm1Dage
(involves: 129P1/ReJ * C57BL/6 * C57BL/6J * SJL)
decreased B cell number J:147914
decreased CD4-positive, alpha-beta T cell number J:147914
decreased CD8-positive, alpha-beta T cell number J:147914
decreased macrophage cell number J:147914
Nr3c1tm1Ljm/Nr3c1tm1Ljm
(involves: 129S6/SvEvTac * C57BL/6)
abnormal thymocyte apoptosis J:82174
Nr3c1tm2.1Gsc/Nr3c1+
(B6.129P2-Nr3c1tm2.1Gsc)
decreased T cell apoptosis J:126427
increased susceptibility to experimental autoimmune encephalomyelitis J:137157
Nr3c1tm2.1Ljm/Nr3c1tm2.1Ljm
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
abnormal interleukin-6 secretion J:197150
abnormal monocyte cell number J:197150
increased interleukin-1 beta secretion J:197150
Nr3c1tm2Gsc/Nr3c1tm2Gsc
Lyz2tm1(cre)Ifo/Lyz2+

(B6.129P2-Lyz2tm1(cre)Ifo Nr3c1tm2Gsc)
immune system phenotype J:137157
Nr3c1tm2Gsc/Nr3c1tm2Gsc
Tg(Lck-cre)I57Jxm/0

(B6.Cg-Nr3c1tm2Gsc Tg(Lck-cre)I57Jxm)
decreased T cell apoptosis J:137157
increased susceptibility to experimental autoimmune encephalomyelitis J:137157
Nr3c1tm2Ljm/Nr3c1tm2Ljm
Tg(Lck-cre)548Jxm/?

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
abnormal interferon level J:97484
abnormal interleukin level J:97484
abnormal tumor necrosis factor level J:97484
cecum inflammation J:97484
increased susceptibility to endotoxin shock J:97484
Nr4a1tm1Jmi/Nr4a1tm1Jmi
(involves: 129S2/SvPas)
decreased B cell apoptosis J:306652
immune system phenotype J:77686
increased B cell proliferation J:306652
Nr4a1tm1Jmi/Nr4a1tm1Jmi
(involves: 129S2/SvPas * C57BL/6)
decreased Ly6C low monocyte number J:239509
increased susceptibility to endotoxin shock J:239509
Nr4a1tm1Jmi/Nr4a1tm1Jmi
Nr4a3tm1Omc/Nr4a3tm1Omc

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6)
abnormal leukopoiesis J:121903
abnormal myelopoiesis J:121903
abnormal spleen morphology J:121903
abnormal thymus morphology J:121903
decreased lymphocyte cell number J:121903
enlarged lymph nodes J:121903
enlarged spleen J:121903
increased eosinophil cell number J:121903
increased granulocyte number J:121903
increased leukocyte cell number J:121903
increased neutrophil cell number J:121903
Nr4a1tm1Pcn/Nr4a1tm1Pcn
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:205658
Nr4a1tm1Pcn/Nr4a1tm1Pcn
Tg(Cr2-cre)3Cgn/0

(involves: 129)
increased B cell proliferation J:306652
Nr4a2tm1.1Pcn/Nr4a2+
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129X1/SvJ)
abnormal regulatory T cell morphology J:205658
Nr4a2tm1.1Pcn/Nr4a2tm1.1Pcn
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NTac)
abnormal regulatory T cell morphology J:205658
abnormal T-helper 1 cell differentiation J:205658
abnormal T-helper 17 cell differentiation J:205658
Nr4a2tm1.1Pcn/Nr4a2tm1.1Pcn
Tg(Lck-cre)1Jtak/0

(Not Specified)
abnormal regulatory T cell morphology J:205658
abnormal T-helper 1 cell differentiation J:205658
abnormal T-helper 17 cell differentiation J:205658
decreased regulatory T cell number J:205658
immune system phenotype J:205658
increased CD4-positive, alpha-beta T cell number J:205658
increased susceptibility to induced colitis J:205658
increased T-helper 1 cell number J:205658
Nr5a2tm1Auw/Nr5a2+
(involves: 129P2/OlaHsd)
increased susceptibility to induced colitis J:123697
Nr5a2tm1Sjns/Nr5a2tm1Sjns
Tg(Vil1-cre/ERT2)23Syr/?

(involves: 129/Sv * C57BL/6 * DBA/2 * SJL)
increased susceptibility to induced colitis J:123697
Nrastm1.1Emfu/Nrastm1.1Emfu
(involves: 129S1/Sv * FVB/N)
abnormal granulocyte differentiation J:189834
abnormal leukocyte cell number J:189834
abnormal thymus morphology J:189834
decreased monocyte cell number J:189834
decreased spleen weight J:189834
increased granulocyte number J:189834
increased T cell number J:189834
Nrastm1Tyj/Nrastm1Tyj
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal myelopoiesis J:174880
enlarged spleen J:204263, J:174880
increased leukocyte cell number J:204263
increased monocyte cell number J:204263
increased neutrophil cell number J:204263
myeloid hyperplasia J:204263
Nrbp1tm3b(EUCOMM)Wtsi/Nrbp1+
(C57BL/6N-Nrbp1tm3b(EUCOMM)Wtsi/Wtsi)
decreased CD4-positive, alpha-beta T cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
Nrp1tm1Ddg/Nrp1tm1Ddg
(involves: 129P2/OlaHsd)
abnormal dendritic cell physiology J:161856
abnormal T cell physiology J:161856
Nrp2tm1.2Mom/Nrp2+
Sema3ftm1.2Ddg/Sema3f+

(involves: 129P2/OlaHsd)
abnormal lymphatic vessel endothelial cell morphology J:226501
Nrp2tm1.2Mom/Nrp2tm1.2Mom
(involves: 129P2/OlaHsd)
abnormal lymphatic system physiology J:226501
abnormal lymphatic vessel endothelial cell morphology J:226501
abnormal lymphatic vessel morphology J:226501
lymphatic vessel hyperplasia J:226501
Nrp2tm1Ddg/Nrp2tm1Ddg
(involves: C57BL/6)
abnormal lymphangiogenesis J:156869
Nrrostm1Lex/Nrrostm1Lex
(B6.129S5-Nrrostm1Lex)
decreased susceptibility to infection J:209569
increased susceptibility to experimental autoimmune encephalomyelitis J:209569
Nrsn2em1(IMPC)Kmpc/Nrsn2em1(IMPC)Kmpc
(C57BL/6NTac-Nrsn2em1(IMPC)Kmpc/Kmpc)
abnormal lymph node morphology J:211773
Nrtntm1Jmi/Nrtntm1Jmi
(involves: 129X1/SvJ * C57BL/6)
increased incidence of corneal inflammation J:85753
keratoconjunctivitis sicca J:85753
Nrxn1tm1b(KOMP)Wtsi/Nrxn1+
(C57BL/6N-Nrxn1tm1b(KOMP)Wtsi/H)
small thymus J:211773
Nsa2em1(IMPC)Mbp/Nsa2+
(C57BL/6N-Nsa2em1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
(C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H)
small spleen J:211773
Nsg1tm1.1(KOMP)Vlcg/Nsg1tm1.1(KOMP)Vlcg
(C57BL/6N-Nsg1tm1.1(KOMP)Vlcg/Ucd)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Nsl1em1(IMPC)J/Nsl1+
(C57BL/6NJ-Nsl1em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Nsmaftm1Mkr/Nsmaftm1Mkr
(involves: 129P2/OlaHsd)
abnormal T cell physiology J:54972
immune system phenotype J:54972
Nsmaftm1Mkr/Nsmaftm1Mkr
(B6.129P2-Nsmaftm1Mkr)
decreased susceptibility to endotoxin shock J:89524
Nsmce1em1(IMPC)Wtsi/Nsmce1+
(C57BL/6N-Nsmce1em1(IMPC)Wtsi/Wtsi)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Nsmce2tm2.1Ofc/Nsmce2tm2.1Ofc
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129S/SvEv * C57BL/6 * SJL)
abnormal thymus physiology J:227197
Nsrp1tm1.1Cdj/Nsrp1tm1.1Cdj
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal T cell number J:306261
decreased CD4-positive, alpha-beta T cell number J:306261
decreased CD8-positive, alpha-beta T cell number J:306261
immune system phenotype J:306261
increased memory T cell number J:306261
increased T cell apoptosis J:306261
increased T cell proliferation J:306261
Nss1NOD/ShiLtJ/Nss1NOD/ShiLtJ
(involves: C57BL/10 * NOD)
salivary gland inflammation J:73932
Nsun2tm1a(EUCOMM)Wtsi/Nsun2tm1a(EUCOMM)Wtsi
(B6JTyr;B6N-Nsun2tm1a(EUCOMM)Wtsi/Wtsi)
abnormal thymus capsule morphology J:239583
Nsun5tm2b(EUCOMM)Wtsi/Nsun5tm2b(EUCOMM)Wtsi
(C57BL/6N-Nsun5tm2b(EUCOMM)Wtsi/J)
decreased lymphocyte cell number J:211773
decreased spleen weight J:211773
increased neutrophil cell number J:211773
Nsv1C57BL/6J/?
(involves: BALB/cBy * C57BL/6J)
increased susceptibility to viral infection J:71216
Nt5c3em1(IMPC)Tcp/Nt5c3em1(IMPC)Tcp
(C57BL/6NCrl-Nt5c3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Nt5eem1(IMPC)Mbp/Nt5eem1(IMPC)Mbp
(C57BL/6NCrl-Nt5eem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Ntan1tm1Avar/Ntan1tm1Avar
(involves: 129)
abnormal T cell physiology J:62140
decreased splenocyte proliferation J:62140
increased acute inflammation J:62140
Ntaq1tm1.1(KOMP)Vlcg/Ntaq1tm1.1(KOMP)Vlcg
(C57BL/6N-Ntaq1tm1.1(KOMP)Vlcg/J)
increased leukocyte cell number J:211773
Nthl1em1(IMPC)Mbp/Nthl1em1(IMPC)Mbp
(C57BL/6NCrl-Nthl1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Ntn4tm1b(KOMP)Wtsi/Ntn4tm1b(KOMP)Wtsi
(C57BL/6N-Ntn4tm1b(KOMP)Wtsi/Wtsi)
abnormal spleen morphology J:211773
Ntrk1tm1b(EUCOMM)Wtsi/Ntrk1+
(C57BL/6N-Ntrk1tm1b(EUCOMM)Wtsi/H)
increased basophil cell number J:211773
Ntrk1tm1Tes/Ntrk1tm1Tes
Tg(Tuba1-cre)1Tes/0

(involves: 129S1/Sv)
abnormal mast cell physiology J:93578
increased B-1 B cell number J:93578
increased IgG1 level J:93578
increased IgG2a level J:93578
increased IgM level J:93578
increased immunoglobulin level J:93578
Nub1tm1b(EUCOMM)Hmgu/Nub1tm1b(EUCOMM)Hmgu
(C57BL/6N-Nub1tm1b(EUCOMM)Hmgu/Ccpcz)
abnormal spleen morphology J:211773
decreased CD4-negative NK T cell number J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased CD5-positive Ly6C-positive T cell number J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased CD11b-high dendritic cell number J:211773
decreased Ly6C-positive NK T cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
decreased NK cell number J:211773
decreased NK T cell number J:211773
enlarged spleen J:211773
immune system phenotype J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased Ly6C-positive NK T cell number J:211773
Nucb1em1(IMPC)Mbp/Nucb1em1(IMPC)Mbp
(C57BL/6NCrl-Nucb1em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Nucb2tm1.2Vdix/Nucb2tm1.2Vdix
(involves: C57BL/6)
increased interleukin-1 beta secretion J:270674
increased tumor necrosis factor secretion J:270674
Nudctm1c(KOMP)Mbp/Nudctm1c(KOMP)Mbp
Tg(Rho-icre)1Ck/0

(involves: C57BL/6 * C57BL/6N * SJL)
increased microglial cell activation J:346299
Nudt1tm1Tts/Nudt1tm1Tts
Ogg1tm1Yun/Ogg1tm1Yun

(involves: 129S/SvEv * C57BL/6JJcl)
microgliosis J:193978
Nudt2tm1a(EUCOMM)Wtsi/Nudt2tm1a(EUCOMM)Wtsi
(C57BL/6-Nudt2tm1a(EUCOMM)Wtsi)
immune system phenotype J:315167
Nudt7em1Ejj/Nudt7em1Ejj
(involves: C57BL/6N)
increased susceptibility to induced arthritis J:266261
osteoarthritis J:266261
Nudt15em1Maska/Nudt15+
(C57BL/6-Nudt15em1Maska)
decreased neutrophil cell number J:285800
Nudt15em1Maska/Nudt15em1Maska
(C57BL/6-Nudt15em1Maska)
decreased neutrophil cell number J:285800
Nudt21tm1.1Ejwpj/Nudt21tm1.1Ejwpj
Tg(Col1a1-cre/ERT2)1Crm/0

(involves: C57BL/6J * CBA/J)
increased acute inflammation J:283035
Nuggcem1(IMPC)Ccpcz/Nuggcem1(IMPC)Ccpcz
(C57BL/6NCrl-Nuggcem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Nuggctm1Diaz/Nuggctm1Diaz
Edil3Tg(Sox2-cre)1Amc/Edil3+

(involves: C57BL/6 * C57BL/6J * CBA)
abnormal somatic hypermutation frequency J:190402
immune system phenotype J:190402
Nup35m1Apb/Nup35m1Apb
(involves: C57BL/6N)
abnormal macrophage morphology J:235141
Nup85tm1.1Yter/Nup85tm1.1Yter
Tg(CAG-cre/Esr1*)5Amc/0

(involves: C57BL/6 * CBA)
decreased Ly6C high monocyte number J:292726
decreased Ly6C low monocyte number J:292726
decreased macrophage cell number J:292726
Nup98tm1Bmaf/Nup98+
(involves: 129S6/SvEvTac * C57BL/6)
abnormal level of surface class I molecules J:110907
abnormal level of surface class II molecules J:110907
abnormal MHC II cell surface expression on macrophages J:110907
decreased B cell number J:110907
decreased CD4-positive, alpha-beta T cell number J:110907
decreased IgG1 level J:110907
decreased IgG level J:110907
decreased T cell proliferation J:110907
increased T cell proliferation J:110907
Nup155em1(IMPC)Mbp/Nup155+
(C57BL/6N-Nup155em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Nup210enuI476T/Nup210enuI476T
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal alpha-beta T cell morphology J:266693
decreased CD4-positive, alpha-beta T cell number J:266693
Nup210enuI476T/Nup210tm1a(EUCOMM)Hmgu
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N)
decreased CD4-positive, alpha-beta T cell number J:266693
Nup210tm1.1Mdan/Nup210tm1.1Mdan
(B6.Cg-Nup210tm1.1Mdan)
abnormal CD4-positive, alpha-beta T cell number J:282451
abnormal CD4-positive, alpha-beta T cell physiology J:282451
abnormal lymphocyte morphology J:282451
abnormal T cell activation J:282451
decreased CD4-positive, alpha-beta T cell number J:282451
decreased leukocyte cell number J:282451
increased effector memory T-helper cell number J:282451
Nup210tm1b(EUCOMM)Hmgu/Nup210tm1b(EUCOMM)Hmgu
(involves: C57BL/6N)
decreased alpha-beta T cell number J:266693
decreased CD4-positive, alpha-beta T cell number J:266693
decreased CD8-positive, alpha-beta T cell number J:266693
decreased T cell number J:266693
immune system phenotype J:266693
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:266693
increased CD8-positive, alpha-beta T cell number J:266693
increased central memory CD8 positive, alpha-beta T cell number J:266693
increased T-helper 1 cell number J:266693
Nup210tm1Mdan/Nup210tm1Mdan
Tg(Cd4-cre/ERT2)11Gnri/0

(involves: 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:282451
Nus1tm1Wcsa/Nus1tm1Wcsa
Tg(Cdh5-cre/ERT2)1Rha/0

(Not Specified)
abnormal jugular lymph sac morphology J:230506
Nwa2NZW/LacJ/Nwa2NZW/LacJ
(involves: BALB/cJ * NZW/LacJ)
increased anti-histone antibody level J:35434
increased anti-single stranded DNA antibody level J:35434
Nwd2em1(IMPC)Ccpcz/Nwd2em1(IMPC)Ccpcz
(C57BL/6N-Nwd2em1(IMPC)Ccpcz/Ccpcz)
decreased CD8-positive, naive alpha-beta T cell number J:211773
Nxntm1b(EUCOMM)Wtsi/Nxn+
(C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Ccpcz)
increased effector memory CD8-positive, alpha-beta T cell number J:211773
Nxnl1tm1.2Tlev/Nxnl1tm1.2Tlev
(involves: BALB/c * BALB/cJ * C57BL/6)
microgliosis J:186370
Nxnl2em1(IMPC)Ccpcz/Nxnl2+
(C57BL/6NCrl-Nxnl2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Nxnl2em1(IMPC)Ccpcz/Nxnl2em1(IMPC)Ccpcz
(C57BL/6NCrl-Nxnl2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Oas1bFlv-mr/Oas1bFlv-mr
(MOLD/RkJ)
decreased susceptibility to Flaviviridae infection J:3674
Oas1bFlv-r/Oas1bFlv-r
(multiple strains)
decreased susceptibility to Flaviviridae infection J:15009
Oas1bFlv-r/Oas1bFlv-r
(C3.PRI-Oas1bFlv-r)
decreased susceptibility to Flaviviridae infection J:175365
Oas1bFlv-s/Oas1bFlv-s
(multiple strains)
increased susceptibility to Flaviviridae infection J:15009
Oas1btm1.1Brin/Oas1btm1.1Brin
(involves: 129X1/SvJ * C57BL/6J)
decreased susceptibility to Flaviviridae infection J:175365
Oas1cem1(IMPC)Ccpcz/Oas1cem1(IMPC)Ccpcz
(C57BL/6N-Oas1cem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small spleen J:211773
Oasl1tm1Yjk/Oasl1tm1Yjk
(B6.129P2-Oasl1tm1Yjk)
abnormal circulating interferon level J:194467
decreased susceptibility to Picornaviridae infection J:194467
decreased susceptibility to Picornaviridae infection induced morbidity/mortality J:194467
Oca2p-3Btlr/Oca2p-3Btlr
(C57BL/6J-Oca2p-3Btlr)
abnormal NK cell physiology J:133623
increased susceptibility to bacterial infection J:133623
Oca2p-4Btlr/Oca2p-4Btlr
(C57BL/6J-Oca2p-4Btlr)
immune system phenotype J:133624
increased susceptibility to bacterial infection J:133624
Oca2p-8Btlr/Oca2p-8Btlr
(C57BL/6J-Oca2p-8Btlr)
increased susceptibility to induced colitis J:264643
Oca2p-23DFiOD/Oca2p-x
(Not Specified)
increased spleen weight J:66645
Oca2p-30PUb/Oca2p-x
(Not Specified)
increased spleen weight J:89922
Oca2p-Btlr/Oca2p-Btlr
(C57BL/6J-Oca2p-Btlr)
immune system phenotype J:133621
Ociad1em1(IMPC)J/Ociad1em1(IMPC)J
(C57BL/6NJ-Ociad1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ociad1tm1.1Msin/Ociad1tm1.1Msin
(involves: BALB/cJ * C57BL/6NCrlj * CBA/JNCrlj)
decreased B cell number J:279239
decreased T cell number J:279239
enlarged spleen J:279239
increased granulocyte number J:279239
increased macrophage cell number J:279239
increased monocyte cell number J:279239
increased neutrophil cell number J:279239
increased spleen germinal center size J:279239
OclnGt(ROSA)39Tshi/OclnGt(ROSA)39Tshi
(involves: DBA/2)
stomach inflammation J:110222
Oclntm1Sts/Oclntm1Sts
(involves: 129S4/SvJae * C57BL/6)
stomach inflammation J:99467
Oclntm1Tshi/Oclntm1Tshi
(involves: C57BL/6 * DBA/2)
stomach inflammation J:110222
Oclntm2Sts/Oclntm2Sts
(involves: 129S4/SvJae * C57BL/6)
stomach inflammation J:99467
Ocstamptm2a(KOMP)Wtsi/Ocstamptm2a(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
abnormal osteoclast morphology J:233553
Odad2b2b227.1Clo/Odad2b2b227.1Clo
(C57BL/6J-Odad2b2b227.1Clo)
spleen hypoplasia J:175213
Odad2em1(IMPC)Mbp/Odad2em1(IMPC)Mbp
(C57BL/6N-Odad2em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Odad3b2b1885Clo/Odad3b2b1885Clo
(C57BL/6J-Odad3b2b1885Clo)
spleen hypoplasia J:175213
Odad3tm1b(EUCOMM)Hmgu/Odad3tm1b(EUCOMM)Hmgu
(C57BL/6N-Odad3tm1b(EUCOMM)Hmgu/Cnrm)
abnormal spleen morphology J:278798
absent spleen J:278798
enlarged spleen J:278798
Odaphem1(IMPC)Ccpcz/Odaphem1(IMPC)Ccpcz
(C57BL/6NCrl-Odaphem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Odf2tm1.1Sats/Odf2tm1.2Sats
Tg(CAG-cre)13Miya/0

(involves: C57BL/6 * C57BL/6J)
immune system phenotype J:181294
increased susceptibility to otitis media J:181294
sinus inflammation J:181294
oed/oed
(STOCK pc-oed)
increased granulocyte number J:5609
increased leukocyte cell number J:5609
Ogdhtm1e(KOMP)Wtsi/Ogdh+
(C57BL/6N-Ogdhtm1e(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
Ogg1tm1Yun/Ogg1tm1Yun
(involves: 129S/SvEv * C57BL/6JJcl)
microgliosis J:193978
Ogntm1b(KOMP)Wtsi/Ogntm1b(KOMP)Wtsi
(C57BL/6N-Ogntm1b(KOMP)Wtsi/J)
decreased leukocyte cell number J:211773
Ogttm1Gwh/Y
Tg(Lck-cre)548Jxm/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
decreased CD4-positive, alpha-beta T cell number J:93112
decreased CD8-positive, alpha-beta T cell number J:93112
decreased double-positive T cell number J:93112
decreased T cell number J:93112
decreased thymocyte number J:93112
increased T cell apoptosis J:93112
oh/oh
(Not Specified)
increased macrophage cell number J:5300
Olfm4tm1Gpro/Olfm4tm1Gpro
(involves: 129X1/SvJ * Black Swiss)
abnormal cytokine level J:161279
increased circulating interleukin-3 level J:161279
increased circulating interleukin-12 level J:161279
increased susceptibility to bacterial infection J:161279
stomach inflammation J:161279
Olr1tm1Meht/Olr1tm1Meht
(B6.129X1-Olr1tm1Meht/Meht)
increased circulating interleukin-10 level J:130794
Oma1tm1Otin/Oma1tm1Otin
(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr)
granulomatous inflammation J:184716
Onecut1tm1.1Mga/Onecut1tm1.1Mga
Tg(Pdx1-cre)89.1Dam/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL)
pancreas inflammation J:155058
Opn3em1(IMPC)Mbp/Opn3em1(IMPC)Mbp
(C57BL/6NCrl-Opn3em1(IMPC)Mbp/Mmucd)
increased basophil cell number J:211773
Oprl1em1(IMPC)Mbp/Oprl1em1(IMPC)Mbp
(C57BL/6N-Oprl1em1(IMPC)Mbp/MbpMmucd)
enlarged spleen J:211773
Oprm1tm1Lyu/Oprm1+
(involves: Black Swiss)
increased splenocyte proliferation J:39864
Oprm1tm1Lyu/Oprm1tm1Lyu
(involves: Black Swiss)
increased splenocyte proliferation J:39864
Optntm1.2Jda/Optntm1.2Jda
(involves: 129S4/SvJae * C57BL/6J)
immune system phenotype J:207113
Optntm1.2Jda/Optntm1.2Jda
(B6.Cg-Optntm1.2Jda)
immune system phenotype J:207113
Or1e32em1(IMPC)Mbp/Or1e32em1(IMPC)Mbp
(C57BL/6NCrl-Or1e32em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Or9g4em1(IMPC)Mbp/Or9g4em1(IMPC)Mbp
(C57BL/6N-Or9g4em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Orai1Gt(XL922)Byg/Orai1+
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal mast cell physiology J:130479
decreased interferon-gamma secretion J:130479
Orai1Gt(XL922)Byg/Orai1Gt(XL922)Byg
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal mast cell physiology J:130479
decreased interferon-gamma secretion J:130479
decreased interleukin-2 secretion J:130479
decreased susceptibility to type I hypersensitivity reaction J:130479
Orai1tm1.1Hjm/Orai1tm1.1Hjm
Orai2tm1.1(KOMP)Vlcg/Orai2tm1.1(KOMP)Vlcg
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Tg(Cd4-cre)1Cwi Orai1tm1.1Hjm Orai2tm1.1(KOMP)Vlcg)
abnormal CD4-positive helper T cell morphology J:241365
abnormal T cell physiology J:241365
decreased germinal center B cell number J:241365
decreased IgG level J:241365
decreased regulatory T cell number J:241365
decreased single-positive T cell number J:241365
immune system phenotype J:241365
lymph node hyperplasia J:241365
spleen hyperplasia J:241365
Orai1tm1.1Hjm/Orai1tm1.1Hjm
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Orai1tm1.1Hjm Tg(Cd4-cre)1Cwi)
abnormal T cell physiology J:241365
Orai1tm1Rao/Orai1+
(C57BL/6-Orai1tm1Rao)
abnormal B cell activation J:139730
abnormal T cell activation J:139730
Orai1tm1Rao/Orai1tm1Rao
(involves: C57BL/6NTac * ICR)
abnormal B cell activation J:139730
abnormal cell-mediated immunity J:139730
abnormal cytokine secretion J:139730
abnormal mast cell physiology J:139730
abnormal T cell activation J:139730
abnormal thymocyte activation J:139730
blepharitis J:139730
decreased interferon-gamma secretion J:139730
decreased interleukin-2 secretion J:139730
decreased interleukin-4 secretion J:139730
decreased interleukin-10 secretion J:139730
Orai2tm1.1(KOMP)Vlcg/Orai2tm1.1(KOMP)Vlcg
(B6.Cg-Orai2tm1.1(KOMP)Vlcg)
abnormal macrophage physiology J:241365
abnormal T cell physiology J:241365
Orai2tm1.1Itl/Orai2tm1.1Itl
Tg(Cma1-cre)#Roer/0

(involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N)
increased susceptibility to type I hypersensitivity reaction J:278536
Orai2tm1.2Itl/Orai2tm1.2Itl
(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6N)
abnormal mast cell physiology J:278536
increased mast cell degranulation J:278536
Orch4BALB/cByJ/Orch4BALB/cByJ
(involves: BALB/cByJ * DBA/2)
testis inflammation J:35331
Orch4BALB/cByJ/Orch4DBA/2J
(involves: BALB/cByJ * DBA/2)
decreased inflammatory response J:35331
Orch4DBA/2J/Orch4DBA/2J
(involves: BALB/cByJ * DBA/2)
decreased inflammatory response J:35331
Orch5BALB/cByJ/Orch5BALB/cByJ
(involves: BALB/cByJ * DBA/2)
testis inflammation J:35331
Orch5BALB/cByJ/Orch5DBA/2J
(involves: BALB/cByJ * DBA/2)
decreased inflammatory response J:35331
Orch5DBA/2J/Orch5DBA/2J
(involves: BALB/cByJ * DBA/2)
decreased inflammatory response J:35331
Orgwq1M16i/?
(involves: CAST/Ei * M16i)
increased spleen weight J:78471
Orgwq2M16i/?
(involves: CAST/Ei * M16i)
increased spleen weight J:78471
Orgwq6M16i/?
(involves: CAST/Ei * M16i)
increased spleen weight J:78471
Orgwq7M16i/?
(involves: CAST/Ei * M16i)
increased spleen weight J:78471
Orgwq8M16i/?
(involves: CAST/Ei * M16i)
increased spleen weight J:78471
Orm2em1Bcgen/Orm2em1Bcgen
(involves: C57BL/6J)
liver inflammation J:333118
Orm2tm1(KOMP)Vlcg/Orm2tm1(KOMP)Vlcg
(C57BL/6N-Orm2tm1(KOMP)Vlcg/Mmucd)
kidney inflammation J:292194
Ormdl2em1Pdra/Ormdl2em1Pdra
(C57BL/6-Ormdl2em1Pdra)
immune system phenotype J:328837
Ormdl2em1Pdra/Ormdl2em1Pdra
Ormdl3em1Pdra/Ormdl3em1Pdra

(C57BL/6-Ormdl2em1Pdra Ormdl3em1Pdra)
abnormal mast cell physiology J:328837
abnormal type I hypersensitivity reaction J:328837
increased interleukin-4 secretion J:328837
increased interleukin-6 secretion J:328837
increased mast cell degranulation J:328837
increased tumor necrosis factor secretion J:328837
Ormdl3em1Pdra/Ormdl3em1Pdra
(C57BL/6-Ormdl3em1Pdra)
abnormal mast cell physiology J:328837
abnormal type I hypersensitivity reaction J:328837
increased mast cell degranulation J:328837
Ormdl3em1Quli/Ormdl3em1Quli
(Not Specified)
abnormal spleen morphology J:251260
abnormal splenic cell ratio J:251260
small spleen J:251260
Os/Os+
(ROP/GnLeJ)
glomerulonephritis J:28323
Osbpem1(IMPC)Tcp/Osbp+
(C57BL/6NCrl-Osbpem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Oscartm1Ywc/Oscartm1Ywc
(involves: 129P2/OlaHsd)
abnormal osteoclast differentiation J:178250
Oscartm1Ywc/Oscartm1Ywc
Tyrobptm1Ttk/Tyrobptm1Ttk

(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:178250
abnormal osteoclast morphology J:178250
abnormal osteoclast physiology J:178250
decreased osteoclast cell number J:178250
Osmrtm1Mtan/Osmrtm1Mtan
(B6.129S-Osmrtm1Mtan)
increased circulating interleukin-10 level J:214124
increased circulating tumor necrosis factor level J:214124
increased inflammatory response J:214124
white adipose tissue inflammation J:214124
Ostm1gl/Ostm1gl
(GL/Le Edardl-J +/+ Ostm1gl/J)
eye inflammation J:13053
Otcem1(IMPC)Tcp/Otc+
(C57BL/6NCrl-Otcem1(IMPC)Tcp/Tcp)
enlarged thymus J:211773
Otcspf-ash/Y
(involves: C57BL/6)
increased susceptibility to parasitic infection J:23205
Otcspf-ash/Y
(B6EiC3Sn a/A-Otcspf-ash/J)
increased susceptibility to endotoxin shock J:108979
Otop1em1(IMPC)Ccpcz/Otop1em1(IMPC)Ccpcz
(C57BL/6NCrl-Otop1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Otub1tm1c(EUCOMM)Hmgu/Otub1tm1c(EUCOMM)Hmgu
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N)
abnormal B cell activation J:280549
abnormal follicular B cell morphology J:280549
decreased B-1 B cell number J:280549
decreased immature B cell number J:280549
decreased T cell number J:280549
enlarged spleen J:280549
increased anti-double stranded DNA antibody level J:280549
increased anti-nuclear antigen antibody level J:280549
increased B cell number J:280549
increased B-2 B cell number J:280549
increased circulating interleukin-6 level J:280549
increased IgA level J:280549
increased IgG2a level J:280549
increased IgG2b level J:280549
increased IgM level J:280549
increased immunoglobulin level J:280549
increased marginal zone B cell number J:280549
increased mature B cell number J:280549
increased susceptibility to autoimmune disorder J:280549
increased susceptibility to systemic lupus erythematosus J:280549
Otud1em2Gpt/Otud1em2Gpt
(C57BL/6-Otud1em2Gpt)
abnormal innate immunity J:287309
decreased susceptibility to Herpesvirales infection J:287309
decreased susceptibility to Riboviria infection J:287309
increased circulating interferon-beta level J:287309
increased susceptibility to endotoxin shock J:287309
Otud3em1Nju/Otud3em1Nju
(involves: C57BL/6N)
abnormal chemokine secretion J:294274
decreased susceptibility to Riboviria infection J:294274
decreased susceptibility to Riboviria infection induced morbidity/mortality J:294274
increased interferon-beta secretion J:294274
Otud5tm1Vmd/Otud5tm1Vmd
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal T-helper 17 cell differentiation J:219495
decreased regulatory T cell number J:219495
decreased thymocyte number J:219495
immune system phenotype J:219495
increased circulating interleukin-17 level J:219495
increased interleukin-9 secretion J:219495
increased interleukin-17 secretion J:219495
increased interleukin-21 secretion J:219495
intestinal inflammation J:219495
Otud5tm1Vmd/Otud5tm1Vmd
Tg(Vav1-cre)#Cgp/0

(involves: C57BL/6)
abnormal T-helper 17 cell differentiation J:219495
Otud6aem1Smoc/Otud6aem1Smoc
(C57BL/6J-Otud6aem1Smoc)
abnormal innate immunity J:345141
decreased susceptibility to Herpesvirales infection J:345141
decreased susceptibility to Riboviria infection J:345141
Otud6atm1(KOMP)Vlcg/Otud6atm1(KOMP)Vlcg
(C57BL/6N-Otud6atm1(KOMP)Vlcg/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Otud6btm1b(EUCOMM)Wtsi/Otud6b+
(C57BL/6N-Otud6btm1b(EUCOMM)Wtsi/Wtsi)
increased basophil cell number J:211773
Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
(involves: C57BL/6N)
abnormal granulocyte physiology J:209709
Otud7btm1Dgen/Otud7btm1Dgen
(involves: 129 * C57BL/6)
decreased activation-induced B cell apoptosis J:194553
decreased susceptibility to bacterial infection J:194553
decreased susceptibility to bacterial infection induced morbidity/mortality J:194553
increased B cell number J:194553
increased B cell proliferation J:194553
increased IgA level J:194553
lymphoid hyperplasia J:194553
Otulinem1(IMPC)Bay/Otulin+
(C57BL/6N-Otulinem1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Otulinem1Gvl/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0

(involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA/2)
dermatitis J:312394
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0

(involves: C57BL/6 * C57BL/6N * DBA/2)
dermatitis J:312394
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak

(involves: 129S2/SvPas * C57BL/6 * C57BL/6N * DBA/2)
immune system phenotype J:312394
Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg
(involves: BALB/c * C57BL/6NTac)
abnormal immune system physiology J:198383
Oxsr1tm1.1Arte/Oxsr1+
(involves: 129S/SvEvBrd)
abnormal dendritic cell morphology J:191351
abnormal dendritic cell physiology J:191351
P2rx2tm1Ckn/P2rx2tm1Ckn
P2rx3tm1Ckn/P2rx3tm1Ckn

(involves: 129P2/OlaHsd * C57BL/6)
lung inflammation J:86890
P2rx4tm1Dgen/P2rx4tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:145232
P2rx5tm1Lex/P2rx5tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased CD8-positive, alpha-beta T cell number J:82809
increased NK cell number J:82809
P2rx7tm1Gab/P2rx7tm1Gab
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * DBA/2))
abnormal interleukin-6 secretion J:66835
decreased interleukin-1 beta secretion J:66835
increased osteoclast cell number J:84145
P2rx7tm1Gab/P2rx7tm1Gab
(B6.129P2-P2rx7tm1Gab/J)
abnormal mast cell physiology J:190651
P2rx7tm1Ipch/P2rx7tm1Ipch
(B6.Cg-P2rx7tm1Ipch)
abnormal inflammatory response J:101945
P2rx7tm1Ipch/P2rx7tm1Ipch
(involves: 129)
immune system phenotype J:97422
P2rx7tm1Ipch/P2rx7tm1Ipch
(involves: 129 * C57BL/6)
abnormal macrophage physiology J:118561
P2rx7tm1Lex/P2rx7tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal macrophage physiology J:145020
P2ry6tm1.1Brob/P2ry6tm1.1Brob
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal macrophage physiology J:169742
P2ry6tm1Jabo/P2ry6tm1Jabo
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: 129 * C57BL/6 * C57BL/6NTac)
decreased IgE level J:179177
decreased T cell apoptosis J:179177
increased eosinophil cell number J:179177
increased interferon-gamma secretion J:179177
increased interleukin-4 secretion J:179177
increased interleukin-5 secretion J:179177
increased interleukin-13 secretion J:179177
increased neutrophil cell number J:179177
increased T cell proliferation J:179177
lung inflammation J:179177
P2ry6tm1Jabo/P2ry6tm1Jabo
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(B6.Cg-Gt(ROSA)26Sortm9(cre/ESR1)Arte P2ry6tm1Jabo)
increased eosinophil cell number J:179177
increased interferon-gamma secretion J:179177
increased interleukin-4 secretion J:179177
increased interleukin-5 secretion J:179177
increased interleukin-13 secretion J:179177
increased neutrophil cell number J:179177
lung inflammation J:179177
P2ry14tm1.1Shbg/P2ry14tm1.1Shbg
(involves: 129S6/SvEvTac * C57BL/6)
increased spleen weight J:223427
P4hbtm1.1Geno/P4hbtm1.2Geno
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
decreased neutrophil cell number J:197556
impaired neutrophil recruitment J:197556
p23-ST1/p23-ST1
(C57BL/6J-p23-ST1)
microgliosis J:158278
Paam1MRL/MpJ/Paam1MRL/MpJ
(involves: C3H/HeJ * MRL/MpJ)
increased susceptibility to autoimmune disorder J:76107
Paam2MRL/MpJ/Paam2MRL/MpJ
(involves: C3H/HeJ * MRL/MpJ)
increased susceptibility to autoimmune disorder J:76107
Pabir2em1(IMPC)Ccpcz/Y
(C57BL/6NCrl-Pabir2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small spleen J:211773
Pabir2em1(IMPC)Ccpcz/Pabir2em1(IMPC)Ccpcz
(C57BL/6NCrl-Pabir2em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Pabpc5em1(IMPC)Mbp/Y
(C57BL/6N-Pabpc5em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Pacsin1Gt(OST287788)Lex/Pacsin1Gt(OST287788)Lex
(B6.129S5-Pacsin1Gt(OST287788)Lex)
abnormal plasmacytoid dendritic cell physiology J:187784
decreased circulating interferon-alpha level J:187784
decreased interferon-alpha secretion J:187784
immune system phenotype J:187784
Padi2tm1Lex/Padi2tm1Lex
(B6.129S5-Padi2tm1Lex)
abnormal mast cell physiology J:190651
Padi2tm1Lex/Padi2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
autoimmune response J:190651
Padi4em1(IMPC)Mbp/Padi4em1(IMPC)Mbp
(C57BL/6N-Padi4em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Padi4tm1.1Kmow/Padi4tm1.1Kmow
(involves: BALB/cJ * C57BL/6)
abnormal neutrophil physiology J:174934
decreased susceptibility to Orthomyxoviridae infection J:174934
Padi4tm1.1Kmow/Padi4tm1.1Kmow
Tg(CMV-cre)1Cgn/0

(involves: BALB/cJ * C57BL/6)
immune system phenotype J:190651
Padi4tm1.1Ywan/Padi4tm1.1Ywan
(involves: 129S4/SvJae)
abnormal neutrophil physiology J:165718
impaired neutrophil phagocytosis J:165718
increased susceptibility to bacterial infection J:165718
Pag1tm1.1Tara/Pag1tm1.1Tara
(C57BL/6-Pag1tm1.1Tara)
immune system phenotype J:159011
Pag1tm1Kplm/Pag1tm1Kplm
(involves: 129P2/OlaHsd * C57BL/6)
increased thymocyte number J:101365
Pag1tm1Tara/Pag1tm1Tara
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
immune system phenotype J:159011
Pahem1(IMPC)Tcp/Pah+
(C57BL/6NCrl-Pahem1(IMPC)Tcp/Tcp)
small spleen J:211773
Paip1em1(IMPC)Tcp/Paip1em1(IMPC)Tcp
(C57BL/6NCrl-Paip1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Pak1tm1Cher/Pak1tm1Cher
(B6.129S2-Pak1tm1Cher)
abnormal mast cell physiology J:142439
decreased mast cell degranulation J:145444
Pak5em1(IMPC)Mbp/Pak5em1(IMPC)Mbp
(C57BL/6N-Pak5em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Palmtm1.2Kili/Palmtm1.2Kili
Tg(Ins2-VEGFC)#Pepr/0

(involves: C57BL/6N)
abnormal lymphangiogenesis J:237034
Palmtm1.2Kili/Palmtm1.2Kili
Tg(RIP1-Tag)2Dh/0
Tg(Ins2-VEGFC)#Pepr/0

(involves: C57BL/6J * C57BL/6N * DBA/2J)
abnormal lymphangiogenesis J:237034
Pals1tm1Caw/Pals1tm1Caw
Tg(rx3-icre)1Mjam/0

(Not Specified)
microgliosis J:184469
Pals2em1(IMPC)Rbrc/Pals2em1(IMPC)Rbrc
(C57BL/6NJcl-Pals2em1(IMPC)Rbrc/Rbrc)
abnormal spleen morphology J:211773
Pan2tm1b(KOMP)Wtsi/Pan2tm1b(KOMP)Wtsi
(C57BL/6N-Pan2tm1b(KOMP)Wtsi/Mhzh)
increased eosinophil cell number J:211773
Pan3em1(IMPC)Tcp/Pan3+
(C57BL/6N-Pan3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Pank1tm1.1Suja/Pank1tm1.1Suja
Pank2tm1.1Suja/Pank2tm1.1Suja

(involves: 129S/SvEv * C57BL/6J * FVB/N)
decreased spleen weight J:189609
small spleen J:189609
Pank2em1(IMPC)Ccpcz/Pank2em1(IMPC)Ccpcz
(C57BL/6NCrl-Pank2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
immune system phenotype J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
Pank3tm1b(KOMP)Mbp/Pank3tm1b(KOMP)Mbp
(C57BL/6N-Pank3tm1b(KOMP)Mbp/Bay)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Panx1tm1.2Vmd/Panx1tm1.2Vmd
(C57BL/6N-Panx1tm1.2Vmd)
abnormal T cell physiology J:173213
immune system phenotype J:173213
Panx2tm1b(KOMP)Wtsi/Panx2tm1b(KOMP)Wtsi
(C57BL/6N-Panx2tm1b(KOMP)Wtsi/Ucd)
increased spleen weight J:211773
Panx3tm1c(KOMP)Wtsi/Panx3tm1c(KOMP)Wtsi
Tg(Col2a1-cre)1Star/0

(involves: C3H * C57BL/6 * C57BL/6J * C57BL/6N)
decreased susceptibility to induced arthritis J:233542
Panx3tm1d(KOMP)Wtsi/Panx3tm1d(KOMP)Wtsi
(involves: BALB/cJ * C3H * C57BL/6 * C57BL/6N)
decreased susceptibility to induced arthritis J:233542
Pappa2tm1Lex/Pappa2tm1Lex
(C57BL/6-Pappa2tm1Lex)
increased spleen weight J:174887
Papss2bm/Papss2bm
(involves: C57BL/6J * LDJ/Le)
arthritis J:166514
Pard3tm1b(KOMP)Wtsi/Pard3+
(C57BL/6N-Pard3tm1b(KOMP)Wtsi/H)
decreased basophil cell number J:211773
decreased spleen weight J:211773
Pargtm1Zqw/Pargtm1Zqw
(involves: 129P2/OlaHsd * C57BL/6)
increased circulating tumor necrosis factor level J:92244
increased susceptibility to endotoxin shock J:92244
Pargtm2b(KOMP)Mbp/Parg+
(C57BL/6N-Pargtm2b(KOMP)Mbp/J)
decreased leukocyte cell number J:211773
Parltm1.1Bdes/Parltm1.1Bdes
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell morphology J:116017
decreased B cell number J:116017
decreased double-positive T cell number J:116017
decreased lymphocyte cell number J:116017
increased T cell apoptosis J:116017
spleen atrophy J:116017
thymus atrophy J:116017
Parltm1.1Bdes/Parltm1.1Bdes
(involves: 129P2/OlaHsd)
abnormal thymus apoptosis J:269785
microgliosis J:269785
spleen atrophy J:269785
thymus atrophy J:269785
Parltm1Bdes/Parltm1Bdes
Tg(Nes-cre)1Kln/0

(involves: 129P2/OlaHsd * C57BL/6 * SJL)
abnormal thymus apoptosis J:269785
spleen atrophy J:269785
thymus atrophy J:269785
Parp1tm1b(EUCOMM)Hmgu/Parp1tm1b(EUCOMM)Hmgu
(C57BL/6N-Parp1tm1b(EUCOMM)Hmgu/Ics)
decreased NK cell number J:211773
immune system phenotype J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
Parp1tm1Jmdm/Parp1tm1Jmdm
(involves: 129S2/SvPas * C57BL/6)
abnormal inflammatory response J:117701
abnormal leukocyte migration J:117701
Parp1tm1Jmdm/Parp1tm1Jmdm
(involves: 129S2/SvPas)
immune system phenotype J:47993
Parp1tm1Zqw/Parp1tm1Zqw
(involves: 129/Sv * C57BL/6)
decreased inflammatory response J:94497
Parp1tm1Zqw/Parp1tm1Zqw
(129S-Parp1tm1Zqw/J)
abnormal microglial cell physiology J:96548
decreased inflammatory response J:95418
Parp1tm1Zqw/Parp1tm1Zqw
(involves: 129S2/SvPas)
immune system phenotype J:146533
Parp1tm2Zqw/Parp1tm2Zqw
(either: (involves: 129P2/OlaHsd * 129/Sv) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal inflammatory response J:93479
abnormal macrophage physiology J:93479
decreased circulating interleukin-1 beta level J:93479
decreased circulating tumor necrosis factor level J:93479
decreased inflammatory response J:93479
decreased susceptibility to endotoxin shock J:93479
Parp9tm1.2Arte/Parp9tm1.2Arte
(involves: C57BL/6N * FVB/N)
abnormal circulating interferon level J:306337
abnormal interferon secretion J:306337
abnormal response to infection J:306337
Parp12tm1.1(KOMP)Vlcg/Parp12tm1.1(KOMP)Vlcg
(C57BL/6N-Parp12tm1.1(KOMP)Vlcg/Ucd)
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Parp14Gt(OST415485)Lex/Parp14Gt(OST415485)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
decreased B cell proliferation J:146533
decreased IgA level J:146533
decreased marginal zone B cell number J:146533
increased B cell apoptosis J:146533
increased B cell proliferation J:146533
increased follicular B cell number J:146533
Parvaem1(IMPC)Ccpcz/Parva+
(C57BL/6NCrl-Parvaem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Parvbtm1a(EUCOMM)Wtsi/Parvbtm1a(EUCOMM)Wtsi
(C57BL/6N-Parvbtm1a(EUCOMM)Wtsi/Cnrm)
decreased mature B cell number J:165965
decreased NK cell number J:165965
decreased T cell number J:165965
Patz1tm1.1Welm/Patz1tm1.1Welm
(involves: 129P2/OlaHsd)
abnormal T cell subpopulation ratio J:158947
decreased splenocyte number J:158947
decreased thymocyte number J:158947
Patz1tm1.1Welm/Patz1tm1.1Welm
Tg(TcraTcrb)425Cbn/0

(involves: C57BL/6)
abnormal T cell subpopulation ratio J:158947
decreased CD8-positive, alpha-beta T cell number J:158947
increased CD4-positive, alpha-beta T cell number J:158947
Patz1tm1.1Welm/Patz1tm1.1Welm
Tg(TcraTcrb)1100Mjb/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell subpopulation ratio J:158947
decreased CD8-positive, alpha-beta T cell number J:158947
increased CD4-positive, alpha-beta T cell number J:158947
Patz1tm1.2Welm/Patz1tm1.2Welm
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(B6.Cg-Patz1tm1.2Welm Commd10Tg(Vav1-icre)A2Kio)
abnormal mast cell differentiation J:209168
decreased interleukin-6 secretion J:209168
immune system phenotype J:209168
Patz1tm1.2Welm/Patz1tm1.2Welm
Tg(Cma1-cre)#Roer/0

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:209168
Pawrtm1Jmos/Pawrtm1Jmos
(involves: 129/Sv * CD-1)
abnormal T-helper 2 physiology J:85495
enlarged spleen J:85495
increased B cell proliferation J:85495
increased lymphocyte cell number J:85495
increased T cell proliferation J:85495
spleen hyperplasia J:85495
Pax1un-i/Pax1+
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J))
decreased CD4-positive, alpha-beta T cell number J:100951
decreased CD8-positive, alpha-beta T cell number J:100951
decreased thymocyte number J:100951
Pax1un-i/Pax1un-i
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J))
decreased CD4-positive, alpha-beta T cell number J:100951
decreased CD8-positive, alpha-beta T cell number J:100951
decreased double-negative T cell number J:100951
decreased double-positive T cell number J:100951
decreased thymocyte number J:100951
increased double-negative T cell number J:100951
Pax1un/Pax1+
Tcf3tm1Cmu/Tcf3tm1Cmu

(involves: 129P2/OlaHsd * C3H * C57BL/6)
abnormal T cell differentiation J:103567
abnormal T cell subpopulation ratio J:103567
Pax3Sp-1H/Pax3Sp-1H
(involves: 101/H * C3H/HeH * C57BL/6)
abnormal thymus morphology J:88412
Pax3tm1(FOXO1A)Gcg/Pax3+
(either: (involves: 129X1/SvJ * C57BL/6) or (involves: 129X1/SvJ * NMRI))
abnormal thymus lobule morphology J:79365
ectopic thymus J:79365
Pax5m1Btlr/Pax5m1Btlr
(C57BL/6J-Pax5m1Btlr)
decreased B cell number J:220072
decreased IgA level J:220072
decreased IgG1 level J:220072
decreased IgG2a level J:220072
decreased IgG2b level J:220072
decreased IgG level J:220072
decreased IgM level J:220072
impaired humoral immune response J:220072
increased macrophage cell number J:220072
increased monocyte cell number J:220072
increased single-positive T cell number J:220072
increased T cell number J:220072
Pax5m2Btlr/Pax5+
(C57BL/6J-Pax5m2Btlr)
decreased B-1b cell number J:254824
Pax5m2Btlr/Pax5m2Btlr
(C57BL/6J-Pax5m2Btlr)
decreased B-1b cell number J:254824
increased B-1 B cell number J:254824
Pax5m3Btlr/Pax5+
(C57BL/6J-Pax5m3Btlr)
decreased B cell number J:254825
Pax5m3Btlr/Pax5m3Btlr
(C57BL/6J-Pax5m3Btlr)
abnormal humoral immune response J:254825
decreased B cell number J:254825
decreased B-1 B cell number J:254825
decreased IgG level J:254825
decreased IgM level J:254825
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254825
increased CD8-positive, alpha-beta memory T cell number J:254825
Pax5m4Btlr/Pax5m4Btlr
(C57BL/6J-Pax5m4Btlr)
decreased IgD level J:265140
Pax5M5Btlr/Pax5M5Btlr
(C57BL/6J-Pax5M5Btlr)
decreased IgD level J:265141
Pax5tm1b(EUCOMM)Wtsi/Pax5+
(C57BL/6N-Pax5tm1b(EUCOMM)Wtsi/Ieg)
decreased leukocyte cell number J:211773
immune system phenotype J:211773
increased CD4-positive NK T cell number J:211773
increased memory-marker CD4-positive NK T cell number J:211773
Pax5tm1Mbu/Pax5tm1Mbu
(involves: 129S2/SvPas * C57BL/6)
abnormal B cell differentiation J:38813
abnormal lymphopoiesis J:38813
absent B-2 B cells J:113076
absent mature B cells J:113076
arrested B cell differentiation J:113076
decreased B cell number J:113076
decreased B-1 B cell number J:113076
decreased immature B cell number J:113076
decreased immunoglobulin level J:113076
increased T cell number J:113076
Pax5tm1Mbu/Pax5tm1Mbu
(involves: 129S2/SvPas)
abnormal B cell physiology J:123629
abnormal immunoglobulin heavy chain V(D)J recombination J:139510
arrested B cell differentiation J:75504
Pax5tm1Mbu/Pax5tm1Mbu
(either: 129 or (involves: 129S2/SvPas * C57BL/6J))
abnormal late pro-B cell J:21935
abnormal lymphopoiesis J:21935
absent late pro-B cells J:21935
arrested B cell differentiation J:21935
Pax5tm1Mbu/Pax5tm3Mbu
Tg(Mx1-cre)1Cgn/?

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * CBA)
decreased mature B cell number J:75504
Pax5tm3.1Mbu/Pax5tm3.1Mbu
(involves: 129P2/OlaHsd * C57BL/6)
arrested B cell differentiation J:75504
Pax5tm3Mbu/Pax5+
Tcf3tm1(PBX1)Mlc/Tcf3+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal pro-B cell morphology J:226241
arrested B cell differentiation J:226241
decreased immature B cell number J:226241
Pax5tm4(CD2*)Mbu/Pax5tm4(CD2*)Mbu
(B6.129P2-Pax5tm4(CD2*)Mbu)
immune system phenotype J:144100
Pax5tm5Mbu/Pax5tm5Mbu
(B6.129P2-Pax5tm5Mbu)
immune system phenotype J:144100
Pax5tm6.1Mbu/Pax5tm6.1Mbu
(B6.129P2-Pax5tm6.1Mbu)
immune system phenotype J:173158
Pax6Sey-4H/Pax6+
(involves: 101/H * C3H/HeCrj * C3H/HeH)
increased susceptibility to induced pancreatitis J:124276
Pax7tm1.1(HBEGF,-EYFP)Mal/Pax7+
(involves: C57BL/6)
myositis J:180899
Pax9tm1.1Hpt/Pax9tm1.1Hpt
Tg(Pgk1-cre)1Lni/?

(involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL)
abnormal thymus lobule morphology J:125026
Pax9tm1Rbal/Pax9tm1Rbal
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
athymia J:49857
Pax9tm1Rbal/Pax9tm1Rbal
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
ectopic thymus J:311535
thymus hypoplasia J:311535
Paxxem1(IMPC)Mbp/Paxxem1(IMPC)Mbp
(C57BL/6NCrl-Paxxem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Paxxem1Spj/Paxxem1Spj
(C57BL/6NTac-Paxxem1Spj)
decreased B cell number J:236776
decreased CD4-positive, alpha-beta T cell number J:236776
decreased CD8-positive, alpha-beta T cell number J:236776
decreased follicular B cell number J:236776
decreased splenocyte number J:236776
decreased T cell number J:236776
decreased transitional stage B cell number J:236776
immune system phenotype J:236776
increased mature B cell number J:236776
Paxxem1Spj/Paxxem1Spj
Nhej1tm1Fwa/Nhej1tm1Fwa

(involves: 129S6/SvEvTac * C57BL/6NTac)
abnormal thymus involution J:236776
absent lymphocyte J:236776
athymia J:236776
decreased spleen weight J:236776
decreased splenocyte number J:236776
small spleen J:236776
Pbat1BXSB/Slc/Pbat1BXSB/Slc
(involves: BXSB/Slc * NZW/Slc)
increased autoantibody level J:49899
Pbat1BXSB/Slc/Pbat1NZW/Slc
(involves: BXSB/Slc * NZW/Slc)
increased autoantibody level J:49899
Pbat2BXSB/Slc/Pbat2BXSB/Slc
(involves: BXSB/Slc * NZW/Slc)
increased autoantibody level J:49899
Pbat2BXSB/Slc/Pbat2NZW/Slc
(involves: BXSB/Slc * NZW/Slc)
increased autoantibody level J:49899
Pbbcp1C57BL/6J/?
(involves: C57BL/6J * DBA/2J)
increased B cell number J:74270
Pbktm1Zgdo/Pbktm1Zgdo
(Not Specified)
decreased interleukin-6 secretion J:176985
increased interleukin-6 secretion J:176985
increased tumor necrosis factor secretion J:176985
Pbrm1tm1Zhwa/Pbrm1tm1Zhwa
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal T-helper 2 cell differentiation J:236906
decreased T cell proliferation J:236906
immune system phenotype J:236906
increased interleukin-4 secretion J:236906
increased interleukin-10 secretion J:236906
Pbwg1.9M. m. castaneus/?
(involves: C57BL/6J * M. m. castaneus)
increased spleen weight J:121981
Pbx1em1Dunw/Pbx1em1Dunw
(C57BL/6J-Pbx1em1Dunw)
ectopic thymus J:320934
spleen hypoplasia J:320934
thymus hypoplasia J:320934
Pbx1tm1.1Koss/Pbx1tm1.1Koss
Tg(WT1-cre)AG11Dbdr/0

(involves: 129P2/OlaHsd * C57BL/6)
spleen hypoplasia J:184521
Pbx1tm1.1Koss/Pbx1tm1.2Koss
Tmem163Tg(ACTB-cre)2Mrt/0

(involves: 129P2/OlaHsd * FVB/N)
absent spleen J:184521
Pbx1tm1Koss/Pbx1tm1Koss
Nkx2-5tm2(cre)Rph/Nkx2-5+

(involves: 129P2/OlaHsd * 129S1/Sv)
abnormal spleen mesenchyme morphology J:184521
abnormal spleen morphology J:184521
spleen hypoplasia J:184521
Pbx1tm1Koss/Pbx1tm1Koss
Pbx2tm1Mlc/Pbx2+
Nkx2-5tm2(cre)Rph/Nkx2-5+

(involves: 129P2/OlaHsd * 129S/Sv * 129S1/Sv)
abnormal spleen morphology J:184521
spleen hypoplasia J:184521
Pbx1tm1Mlc/Pbx1tm1Mlc
(involves: 129S6/SvEvTac * C57BL/6)
absent spleen J:71996, J:70684
ectopic thymus J:71996
Pbx1tm1Mlc/Pbx1tm2.1Mlc
(involves: 129S6/SvEvTac)
abnormal lymph node primary follicle morphology J:132963
decreased CD4-positive, alpha-beta T cell number J:132963
decreased CD8-positive, alpha-beta T cell number J:132963
decreased mature B cell number J:132963
Pbx1tm1Mlc/Pbx1tm3.1Mlc
Tg(Tek-cre)1Ywa/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
abnormal spleen morphology J:149799
abnormal thymus morphology J:149799
decreased B cell number J:149799
decreased double-negative T cell number J:149799
decreased pre-B cell number J:149799
decreased pro-B cell number J:149799
decreased T cell number J:149799
small spleen J:149799
small thymus J:149799
spleen hypoplasia J:149799
thymus hypoplasia J:149799
Pbx2tm1Mlc/Pbx2tm1Mlc
(either: 129S/Sv or (involves: 129S/Sv * C57BL/6))
immune system phenotype J:91079
Pbxip1tm1Cya/Pbxip1tm1Cya
Tg(Col2a1-cre/ERT)KA3Smac/0

(involves: FVB/N)
osteoarthritis J:270267
Pcaretm1Kpal/Pcaretm1Kpal
(involves: C57BL/6J * C57BL/6NTac)
increased microglial cell activation J:220866
Pcd4ts1DBA/2/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Pcd4ts2BALB/c/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Pcd4ts3BALB/c/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:83220
Pcd8ts1C57BL/6/?
(involves: BALB/c * C3H * C57BL/6 * DBA/2)
increased CD8-positive, alpha-beta T cell number J:83220
Pcdh7em1Ywc/Pcdh7em1Ywc
(Not Specified)
decreased osteoclast cell number J:298915
Pcdha2em1(IMPC)Tcp/Pcdha2em1(IMPC)Tcp
(C57BL/6N-Pcdha2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Pcdhb13em1(IMPC)Tcp/Pcdhb13em1(IMPC)Tcp
(C57BL/6N-Pcdhb13em1(IMPC)Tcp/Tcp)
decreased basophil cell number J:211773
enlarged lymph nodes J:211773
Pcdhgem5Rwb/Pcdhgem5Rwb
(C57BL/6J-Pcdhgem5Rwb/Rwb)
microgliosis J:285314
Pcdhgem41Rwb/Pcdhgem41Rwb
(C57BL/6J-Pcdhgem41Rwb/Rwb)
microgliosis J:285314
Pcdhgtm1.1Tman/Pcdhgtm1.1Tman
(involves: 129S4/SvJae * C57BL/6)
microgliosis J:188341
Pcgf2tm1b(KOMP)Mbp/Pcgf2+
(C57BL/6N-Pcgf2tm1b(KOMP)Mbp/Tcp)
abnormal spleen morphology J:211773
small spleen J:211773
Pcgf2tm1Hko/Pcgf2tm1Hko
(involves: BALB/c * C57BL/6)
abnormal T-helper 2 physiology J:71268
decreased lymphocyte cell number J:71268
decreased thymocyte number J:71268
Pcgf3TgTn(sb-cHS4,Tyr)2349AOve/Pcgf3TgTn(sb-cHS4,Tyr)2349AOve
(FVB/N-Pcgf3TgTn(sb-cHS4,Tyr)2349AOve)
absent spleen J:175597
Pcid2tm1Imku/Pcid2tm1Imku
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal spleen B cell follicle morphology J:166080
decreased follicular B cell number J:166080
decreased marginal zone B cell number J:166080
decreased mature B cell number J:166080
Pck2em1(IMPC)Tcp/Pck2em1(IMPC)Tcp
(C57BL/6N-Pck2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Pclaftm1.1Lkd/Pclaftm1.1Lkd
(involves: C57BL/6)
decreased leukocyte cell number J:177782
spleen hypoplasia J:177782
thymus hypoplasia J:177782
Pclaftm1a(EUCOMM)Wtsi/Pclaftm1a(EUCOMM)Wtsi
(C57BL/6N-Pclaftm1a(EUCOMM)Wtsi/Wtsi)
decreased CD11b-high dendritic cell number J:211773
decreased dendritic cell number J:211773
decreased immature NK cell number J:211773
decreased plasmacytoid dendritic cell number J:211773
decreased regulatory T cell number J:211773
decreased T cell number J:211773
increased CD11b-low dendritic cell number J:211773
increased dendritic cell number J:211773
increased mature NK cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased pro-B cell number J:211773
Pcm1em1(IMPC)Tcp/Pcm1em1(IMPC)Tcp
(C57BL/6NCrl-Pcm1em1(IMPC)Tcp/Tcp)
decreased spleen weight J:211773
small spleen J:211773
Pcmt1tm1Shs/Pcmt1tm1Shs
(involves: 129P2/OlaHsd * C57BL/6)
small spleen J:46228
Pcnatm1.1Mdsc/Pcnatm1.1Mdsc
Tg(Pcna*K164R)1Mdsc/0

(involves: FVB/N)
abnormal class switch recombination J:141098
abnormal somatic hypermutation frequency J:141098
Pcnatm1Jcbs/Pcnatm1Jcbs
(involves: 129P2/OlaHsd * C57BL/6)
abnormal somatic hypermutation frequency J:125916
Pcnatm1Jcbs/Pcnatm1Jcbs
(involves: 129P2/OlaHsd)
abnormal somatic hypermutation frequency J:155454, J:177630
Pcnatm1Jcbs/Pcnatm1Jcbs
Ungtm1Tld/Ungtm1Tld

(involves: 129P2/OlaHsd)
abnormal somatic hypermutation frequency J:155454
Pcolce2tm1Ccb/Pcolce2tm1Ccb
Ppp1r16btm1Ccb/Ppp1r16btm1Ccb

(involves: 129S1/Sv * 129X1/SvJ)
immune system phenotype J:124347
Pcsk1tm1Dfs/Pcsk1tm1Dfs
(involves: 129 * C57BL/6J)
abnormal peritoneal macrophage morphology J:184882
abnormal spleen marginal zone morphology J:184882
abnormal spleen white pulp morphology J:184882
abnormal T-helper 1 cell differentiation J:184882
decreased follicular dendritic cell number J:184882
decreased NK T cell number J:184882
decreased T cell number J:184882
enlarged spleen J:184882
increased circulating interferon-gamma level J:184882
increased circulating interleukin-1 beta level J:184882
increased circulating interleukin-6 level J:184882
increased circulating interleukin-10 level J:184882
increased circulating interleukin-12 level J:184882
increased circulating tumor necrosis factor level J:184882
increased interleukin-1 beta secretion J:184882
increased lymphocyte cell number J:184882
increased susceptibility to endotoxin shock J:184882
intermingled spleen red and white pulp J:184882
Pcsk5vcc/Pcsk5vcc
(involves: C57BL/6J)
abnormal thymus lobule morphology J:136243
small thymus J:136243
Pctptm1Bor/Pctptm1Bor
(B6.129P2-Pctptm1Bor)
abnormal macrophage physiology J:115284
increased macrophage apoptosis J:115284
Pcyt1atm1Irt/Pcyt1atm1Irt
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * C57BL/6J)
abnormal immune cell physiology J:65639
abnormal macrophage physiology J:65639
Pdap1em1Rkuhn/Pdap1em1Rkuhn
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N)
abnormal B cell physiology J:298705
abnormal class switch recombination J:298705
abnormal somatic hypermutation frequency J:298705
decreased germinal center B cell number J:298705
decreased mature B cell number J:298705
increased B cell apoptosis J:298705
Pdcd1tm1.1Liux/Pdcd1tm1.1Liux
(involves: C57BL/6)
decreased regulatory T cell number J:190150
increased T-helper 1 cell number J:190150
Pdcd1tm1.1Liux/Pdcd1tm1.1Liux
Tg(MMTV-PyVT)634Mul/0

(involves: C57BL/6 * FVB/N)
decreased interleukin-17 secretion J:190150
decreased regulatory T cell number J:190150
decreased T-helper 2 cell number J:190150
decreased T-helper 17 cell number J:190150
increased interferon-gamma secretion J:190150
increased interleukin-2 secretion J:190150
increased T-helper 1 cell number J:190150
increased tumor necrosis factor secretion J:190150
Pdcd1tm1.1Shr/Pdcd1tm1.1Shr
(involves: C57BL/6)
decreased B-1 B cell number J:153040
increased regulatory T cell number J:153040
Pdcd1tm1.1Shr/Pdcd1tm1.1Shr
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6)
abnormal immune tolerance J:153040
decreased T cell proliferation J:153040
increased susceptibility to autoimmune diabetes J:153040
increased T cell proliferation J:153040
insulitis J:153040
pancreas inflammation J:153040
Pdcd1tm1Hon/Pdcd1tm1Hon
(involves: 129S2/SvPas * C57BL/6)
abnormal immunoglobulin level J:50688
abnormal leukopoiesis J:50688
abnormal myelopoiesis J:50688
enlarged spleen J:50688
increased B cell number J:50688
increased B cell proliferation J:50688
increased B-1 B cell number J:50688
increased IgA level J:50688
increased IgG2b level J:50688
increased IgG3 level J:50688
increased lymphocyte cell number J:50688
Pdcd1tm1Hon/Pdcd1tm1Hon
(B6.129S2-Pdcd1tm1Hon)
abnormal response to transplant J:119356
arthritis J:78802
glomerulonephritis J:78802
Pdcd1tm1Hon/Pdcd1tm1Hon
(C.129S2(B6)-Pdcd1tm1Hon)
increased autoantibody level J:66979
Pdcd1tm1Hon/Pdcd1tm1Hon
(involves: 129S2/SvPas)
abnormal T cell activation J:222944
increased IgA level J:222944
increased IgM level J:222944
increased inflammatory response J:222944
increased interferon-gamma secretion J:222944
Pdcd1tm1Hon/Pdcd1tm1Hon
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: 129S2/SvPas)
decreased susceptibility to experimental autoimmune encephalomyelitis J:140751
Pdcd1tm1Hon/Pdcd1tm1Hon
Vsirtm1Lex/Vsirtm1Lex

(involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6)
abnormal T cell activation J:222944
immune system phenotype J:222944
increased IgA level J:222944
increased IgM level J:222944
increased inflammatory response J:222944
increased interferon-gamma secretion J:222944
increased interleukin-17 secretion J:222944
increased tumor necrosis factor secretion J:222944
Pdcd1tm1Hon/Pdcd1tm1Hon
Vsirtm1Lex/Vsirtm1Lex
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6)
increased susceptibility to experimental autoimmune encephalomyelitis J:222944
Pdcd1tm1Llc/Pdcd1tm1Llc
(involves: 129S5/SvEvBrd)
abnormal cytokine secretion J:126829
decreased CD8-positive, alpha-beta T cell number J:126829
increased susceptibility to experimental autoimmune encephalomyelitis J:126829
Pdcd1lg2tm1.1Lex/Pdcd1lg2tm1.1Lex
(involves: 129S5/SvEvBrd)
decreased CD8-positive, alpha-beta T cell number J:126829
Pdcd1lg2tm1Dmp/Pdcd1lg2tm1Dmp
(involves: 129X1/SvJ * 129S1/Sv * C57BL/6)
abnormal dendritic cell antigen presentation J:84457
Pdcd1lg2tm1Dmp/Pdcd1lg2tm1Dmp
(C.129-Pdcd1lg2tm1Dmp)
abnormal cytokine secretion J:99212
abnormal cytotoxic T cell physiology J:99212
decreased IgG2a level J:99212
decreased T cell proliferation J:99212
Pdcd1lg2tm1Shr/Pdcd1lg2tm1Shr
(involves: 129/Sv * 129S4/SvJae)
increased IgG2a level J:113851
increased IgM level J:113851
increased susceptibility to parasitic infection J:113851
Pdcd1lg2tm2Shr/Pdcd1lg2tm2Shr
(C.B6-Pdcd1lg2tm2Shr)
abnormal dendritic cell physiology J:123785
increased interferon-gamma secretion J:123785
increased interleukin-2 secretion J:123785
Pdcd1lg2tm3Shr/Pdcd1lg2tm3Shr
(involves: C57BL/6 * NOD/MrkTac)
abnormal CD8-positive, alpha-beta T cell physiology J:123785
increased CD4-positive, alpha-beta T cell number J:123785
increased CD8-positive, alpha-beta T cell number J:123785
increased susceptibility to autoimmune diabetes J:123785
insulitis J:123785
lymph node hyperplasia J:123785
Pdcd4tm1Yhcn/Pdcd4tm1Yhcn
(B6.129S6-Pdcd4tm1Yhcn)
abnormal cytokine secretion J:120583
decreased susceptibility to autoimmune diabetes J:120583
decreased susceptibility to experimental autoimmune encephalomyelitis J:120583
Pdcd6ipem1(IMPC)Hmgu/Pdcd6ipem1(IMPC)Hmgu
(C57BL/6N-Pdcd6ipem1(IMPC)Hmgu/Ieg)
enlarged lymph nodes J:211773
Pdcd6ipem1(IMPC)Mbp/Pdcd6ipem1(IMPC)Mbp
(C57BL/6NCrl-Pdcd6ipem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Pdcd7em1(IMPC)Mbp/Pdcd7+
(C57BL/6N-Pdcd7em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Pdcd10tm1Kwhi/Pdcd10tm1.1Kwhi
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?

(involves: C57BL/6 * CBA)
CNS inflammation J:173947
Pde2aem1(IMPC)H/Pde2a+
(C57BL/6NTac-Pde2aem1(IMPC)H/H)
increased neutrophil cell number J:211773
Pde4atm1Mct/Pde4atm1Mct
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:106828
Pde4btm1Mct/Pde4b+
Pde4dtm1Mct/Pde4dtm1Mct

(involves: 129P2/OlaHsd * C57BL/6)
impaired neutrophil recruitment J:94853
Pde4btm1Mct/Pde4btm1Mct
(involves: 129X1/SvJ * C57BL/6)
decreased tumor necrosis factor secretion J:76862
Pde4btm1Mct/Pde4btm1Mct
(involves: 129P2/OlaHsd * C57BL/6)
decreased tumor necrosis factor secretion J:106828
impaired neutrophil chemotaxis J:94853
impaired neutrophil recruitment J:94853
Pde4btm1Mct/Pde4btm1Mct
Pde4dtm1Mct/Pde4d+

(involves: 129P2/OlaHsd * C57BL/6)
impaired neutrophil recruitment J:94853
Pde4dtm1Mct/Pde4dtm1Mct
(involves: 129P2/OlaHsd * C57BL/6)
abnormal tumor necrosis factor level J:94853
immune system phenotype J:106828
impaired neutrophil chemotaxis J:94853
impaired neutrophil recruitment J:94853
Pde5aem1(IMPC)Mbp/Pde5a+
(C57BL/6N-Pde5aem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Pde7aGt(Betageo-puro)1Yang/Pde7aGt(Betageo-puro)1Yang
(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:86923
Pde7btm1Pfi/Pde7btm1Pfi
(involves: 129 * C57BL/6)
immune system phenotype J:322967
Pdgfbtm1Cbet/Pdgfbtm2Cbet
Tg(Tie1-cre)9Ref/0

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal microglial cell morphology J:89186
Pdgfctm1b(EUCOMM)Hmgu/Pdgfc+
(C57BL/6N-Pdgfctm1b(EUCOMM)Hmgu/Ieg)
enlarged spleen J:211773
increased granulocyte number J:211773
increased monocyte cell number J:211773
Pdgfratm8Sor/Pdgfratm8Sor
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(Not Specified)
small thymus J:81153
Pdgfratm8Sor/Pdgfratm8Sor
Pdgfrbtm1Mdt/Pdgfrbtm1Mdt
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: C57BL/6 * CBA)
abnormal thymus development J:122584
thymus hypoplasia J:122584
Pdgfratm12.1Sor/Pdgfra+
(involves: 129 * C57BL/6)
abnormal immune system organ morphology J:146617
Pdgfrbb2b2903Clo/Pdgfrbb2b2903Clo
(C57BL/6J-Pdgfrbb2b2903Clo)
thymus hypoplasia J:175213
Pdha2em1(IMPC)Bay/Pdha2em1(IMPC)Bay
(C57BL/6N-Pdha2em1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Pdia6em1Btlr/Pdia6m1Btlr
(involves: C57BL/6J)
abnormal circulating cytokine level J:288824
abnormal T cell physiology J:288824
decreased B cell number J:288824
decreased double-negative T cell number J:288824
decreased double-positive T cell number J:288824
decreased follicular B cell number J:288824
decreased leukocyte cell number J:288824
decreased lymphocyte cell number J:288824
decreased monocyte cell number J:288824
decreased NK T cell number J:288824
decreased pre-B cell number J:288824
decreased transitional stage B cell number J:288824
increased marginal zone B cell number J:288824
increased marginal zone precursor B cell number J:288824
increased mature B cell number J:288824
spleen hypoplasia J:288824
thymus hypoplasia J:288824
Pdia6m1Btlr/Pdia6m1Btlr
(C57BL/6J-Pdia6m1Btlr)
immune system phenotype J:288824
Pdia6tm1b(EUCOMM)Hmgu/Pdia6+
(C57BL/6N-Pdia6tm1b(EUCOMM)Hmgu/Ieg)
decreased CD4-positive NK T cell number J:211773
enlarged lymph nodes J:211773
Pdik1lem1(IMPC)Mbp/Pdik1lem1(IMPC)Mbp
(C57BL/6NCrl-Pdik1lem1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Pdk2em1(IMPC)Mbp/Pdk2em1(IMPC)Mbp
(C57BL/6N-Pdk2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Pdk4tm1Tok/Pdk4tm1Tok
(B6.129P2-Pdk4tm1Tok)
abnormal osteoclast cell number J:179789
abnormal osteoclast differentiation J:179789
abnormal osteoclast morphology J:179789
Pdlim2tm1Gru/Pdlim2tm1Gru
(Not Specified)
abnormal T-helper 1 physiology J:99108
increased interferon-gamma secretion J:99108
increased susceptibility to bacterial infection J:99108
Pdlim7em1(IMPC)Mbp/Pdlim7em1(IMPC)Mbp
(C57BL/6N-Pdlim7em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Pdlim7Gt(OST445990)Lex/Pdlim7Gt(OST445990)Lex
(B6.129S5-Pdlim7Gt(OST445990)Lex)
increased lymphocyte cell number J:209780
increased monocyte cell number J:209780
Pdpk1tm1.1Mlw/Pdpk1tm1.1Mlw
Rag2tm1Fwa/Rag2tm1Fwa
Tnfrsf4tm2(cre)Nik/Tnfrsf4+
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+

(involves: 129S/SvEv * 129X1/SvJ * C57BL/6)
dermatitis J:226194
Pdpk1tm1.1Mlw/Pdpk1tm1.1Mlw
Tnfrsf4tm2(cre)Nik/Tnfrsf4+
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+

(involves: 129X1/SvJ * C57BL/6)
abnormal regulatory T cell number J:226194
abnormal T cell physiology J:226194
dermatitis J:226194
enlarged lymph nodes J:226194
enlarged spleen J:226194
Pdpk1tm1Dral/Pdpk1tm1Dral
(B6.129P2-Pdpk1tm1Dral)
small spleen J:136089
Pdpk1tm1Mlw/Pdpk1tm1.1Daca
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * BALB/c * C57BL/6 * DBA/2)
abnormal CD8-positive, alpha beta T cell morphology J:165626
decreased NK T cell number J:165626
decreased T cell number J:165626
Pdpk1tm1Mlw/Pdpk1tm1Mlw
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal CD8-positive, alpha beta T cell morphology J:165626
abnormal NK T cell morphology J:165626
abnormal T cell differentiation J:165626
absent NK T cells J:165626
decreased NK T cell number J:165626
decreased T cell number J:165626
decreased T cell proliferation J:165626
immune system phenotype J:165626
Pdpntm1(cre)Mlkn/Pdpntm1(cre)Mlkn
(involves: 129S4/SvJae * C57BL/6)
abnormal lymphatic vessel morphology J:162815
Pdpntm1Mcws/Pdpn+
(involves: 129S6/SvEvTac)
abnormal lymphatic vessel morphology J:94978
lymphangiectasis J:94978
Pdpntm1Mcws/Pdpntm1Mcws
(involves: 129S6/SvEvTac)
abnormal lymph circulation J:94978
abnormal lymphatic vessel morphology J:94978
lymphangiectasis J:94978
Pdpntm2.1Mlkn/Pdpntm2.1Mlkn
Rag1tm1Mom/Rag1tm1Mom
Tg(Pdgfrb-cre)9Rha/0

(involves: 129S7/SvEvBrd * C57BL/6)
absent lymphocyte J:205423
Pdpntm2.1Mlkn/Pdpntm2.1Mlkn
Tg(CAG-cre/Esr1*)5Amc/0

(involves: C57BL/6 * CBA)
abnormal lymph node morphology J:205423
absent peripheral lymph nodes J:205423
Pdpntm2.1Mlkn/Pdpntm2.1Mlkn
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129 * C57BL/6)
abnormal lymphangiogenesis J:235778
Pdpntm2.1Mlkn/Pdpntm2.1Mlkn
Tg(Pdgfrb-cre)9Rha/0

(involves: C57BL/6)
lymph node hemorrhage J:205423
Pdprtm1b(EUCOMM)Wtsi/Pdprtm1b(EUCOMM)Wtsi
(C57BL/6N-Pdprtm1b(EUCOMM)Wtsi/Ics)
decreased large unstained cell number J:211773
Pdss2kd/Pdss2kd
(CBA/H-Pdss2kd)
tubulointerstitial nephritis J:197578
Pdss2kd/Pdss2kd
(B6.CBACaH(CAST)-Pdss2kd)
tubulointerstitial nephritis J:101779
Pdss2tm1Dalg/Pdss2tm1Dalg
Tg(NPHS2-cre)295Lbh/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
tubulointerstitial nephritis J:136670
Pdx1tm1Ted/Pdx1+
(involves: 129P2/OlaHsd)
pancreas inflammation J:82969
Pdx1tm1Ted/Pdx1tm1Ted
(involves: 129P2/OlaHsd)
immune system phenotype J:20779
Pdxpem1(IMPC)J/Pdxpem1(IMPC)J
(C57BL/6NJ-Pdxpem1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Pdzd8tm1b(EUCOMM)Wtsi/Pdzd8+
(C57BL/6N-Pdzd8tm1b(EUCOMM)Wtsi/Wtsi)
increased large unstained cell number J:211773
Pdzk1tm2b(EUCOMM)Wtsi/Pdzk1tm2b(EUCOMM)Wtsi
(C57BL/6N-Pdzk1tm2b(EUCOMM)Wtsi/Wtsi)
abnormal lymphatic vessel morphology J:239583
absent connection between subcutaneous lymph vessels and lymph sac J:239583
blood in lymph vessels J:239583
Pebp1em1(IMPC)Tcp/Pebp1em1(IMPC)Tcp
(C57BL/6NCrl-Pebp1em1(IMPC)Tcp/Tcp)
decreased eosinophil cell number J:211773
enlarged lymph nodes J:211773
small spleen J:211773
Pecam1tm1Mak/Pecam1+
(D1.129P2-Pecam1tm1Mak)
increased susceptibility to induced arthritis J:106275
Pecam1tm1Mak/Pecam1tm1Mak
(D1.129P2-Pecam1tm1Mak)
abnormal leukocyte physiology J:106275
increased interferon-gamma secretion J:106275
increased susceptibility to induced arthritis J:106275
joint inflammation J:106275
Pecam1tm1Mak/Pecam1tm1Mak
(B6.129P2-Pecam1tm1Mak)
abnormal cytokine secretion J:95226
liver inflammation J:95226
spleen vascular congestion J:95226
Pecam1tm1Mak/Pecam1tm1Mak
PitgpC57BL/6/PitgpC57BL/6

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
peritoneal inflammation J:144817
Peli1tm1.1Arte/Peli1tm1.1Arte
(involves: C57BL/6N)
abnormal cytokine secretion J:191578
abnormal peripheral lymph node morphology J:191578
decreased interferon-alpha secretion J:191578
decreased interferon-beta secretion J:191578
decreased interleukin-6 secretion J:191578
decreased interleukin-10 secretion J:191578
decreased interleukin-12 secretion J:191578
decreased tumor necrosis factor secretion J:191578
enlarged lymph nodes J:191578
immune system phenotype J:191578
lymphoid hyperplasia J:191578
Peli1tm1b(EUCOMM)Wtsi/Peli1tm1b(EUCOMM)Wtsi
(C57BL/6N-Peli1tm1b(EUCOMM)Wtsi/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Peli1tm1Tigm/Peli1tm1Tigm
(involves: 129/Sv * C57BL/6)
decreased B cell proliferation J:152781
decreased circulating interferon-beta level J:152781
decreased circulating interleukin-6 level J:152781
decreased circulating interleukin-12b level J:152781
decreased circulating tumor necrosis factor level J:152781
decreased interleukin-12 secretion J:152781
decreased susceptibility to endotoxin shock J:152781
increased B cell apoptosis J:152781
Peli2tm1.1Arte/Peli2tm1.1Arte
(involves: C57BL/6)
abnormal circulating cytokine level J:265431
abnormal cytokine secretion J:265431
decreased circulating interleukin-1 beta level J:265431
decreased interleukin-1 beta secretion J:265431
decreased interleukin-18 secretion J:265431
increased macrophage apoptosis J:265431
Peli3tm1.1Arte/Peli3tm1.1Arte
(involves: C57BL/6NTac)
abnormal dendritic cell physiology J:188556
abnormal macrophage cytokine production J:188556
decreased susceptibility to Picornaviridae infection J:188556
decreased susceptibility to Picornaviridae infection induced morbidity/mortality J:188556
Penk-rstm1Pig/Penk-rstm1Pig
(B6.129-Penk-rstm1Pig)
abnormal T-helper 2 physiology J:62435
decreased T-helper 2 cell number J:62435
lung inflammation J:62435
Pepdtm1a(KOMP)Wtsi/Pepdtm1a(KOMP)Wtsi
(C57BL/6N-Pepdtm1a(KOMP)Wtsi/Ucd)
decreased immature B cell number J:211773
decreased Ly6C-positive NK T cell number J:211773
decreased transitional stage T1 B cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased leukocyte cell number J:211773
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased memory-marker CD4-negative NK T cell number J:211773
increased memory-marker NK cell number J:211773
Pepdtm1b(KOMP)Wtsi/Pepdtm1b(KOMP)Wtsi
(C57BL/6N-Pepdtm1b(KOMP)Wtsi/Ieg)
decreased B cell number J:211773
decreased B-2 B cell number J:211773
decreased CD5-positive Ly6C-positive T cell number J:211773
decreased follicular B cell number J:211773
enlarged lymph nodes J:211773
Perptm1Att/Perptm1Att
(involves: 129S4/SvJae)
decreased thymocyte apoptosis J:86549
Perptm2Att/Perptm2Att
Tg(KRT14-cre/ERT2)1Ipc/0

(involves: 129S4/SvJae)
skin inflammation J:167545
Pex1tm1.1Hrw/Pex1tm1.1Hrw
(involves: C57BL/6NTac)
liver inflammation J:278655
phlebitis J:278655
Pex5tm1Pec/Pex5tm1Pec
Cnptm1(cre)Kan/Cnp+

(involves: 129S1/Sv * 129X1/SvJ)
abnormal inflammatory response J:123503
microgliosis J:123503
Pex7tm1Nbra/Pex7tm1Nbra
(involves: 129S/SvEv * C57BL/6)
liver inflammation J:158845
Pex7tm1Rjaw/Pex7tm1Rjaw
(Swiss)
abnormal osteoclast morphology J:92346
Pex26tm1.1(KOMP)Vlcg/Pex26+
(C57BL/6N-Pex26tm1.1(KOMP)Vlcg/Ucd)
enlarged spleen J:211773
PfasSofa-2J/Pfas+
(B6(Cg)-PfasSofa-2J/GrsrJ)
abnormal transitional stage B cell morphology J:223062
Pfdn1Gt(GTR1.3)1Rul/Pfdn1Gt(GTR1.3)1Rul
(involves: 129)
abnormal B cell activation J:137415
abnormal B cell differentiation J:137415
abnormal B cell morphology J:137415
abnormal neutrophil morphology J:137415
abnormal spleen morphology J:137415
abnormal spleen red pulp morphology J:137415
abnormal spleen white pulp morphology J:137415
abnormal splenic cell ratio J:137415
abnormal T cell activation J:137415
abnormal thymus cell ratio J:137415
abnormal thymus morphology J:137415
decreased B-1 B cell number J:137415
decreased B-2 B cell number J:137415
decreased pre-B cell number J:137415
decreased thymus weight J:137415
sinus inflammation J:137415
small spleen J:137415
spleen hypoplasia J:137415
thymus hypoplasia J:137415
Pfkfb2tm1b(KOMP)Wtsi/Pfkfb2tm1b(KOMP)Wtsi
(C57BL/6N-Pfkfb2tm1b(KOMP)Wtsi/Nju)
decreased neutrophil cell number J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased lymphocyte cell number J:211773
Pfkfb3tm1.1Pec/Pfkfb3tm1.1Pec
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * CBA)
abnormal macrophage morphology J:296552
abnormal macrophage physiology J:296552
Pfkmtm1Fbos/Pfkmtm1Fbos
(involves: 129S6/SvEvTac * C57BL/6J)
enlarged spleen J:152153
increased spleen weight J:152153
Pgam1tm1.1Hiko/Pgam1tm1.1Hiko
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal CD4-positive T cell differentiation J:293746
abnormal CD8-positive, alpha-beta T cell differentiation J:293746
abnormal effector T cell number J:293746
decreased acute inflammation J:293746
decreased CD4-positive, alpha-beta T cell number J:293746
decreased CD8-positive, alpha-beta T cell number J:293746
decreased interleukin-2 secretion J:293746
decreased NK T cell number J:293746
decreased susceptibility to experimental autoimmune encephalomyelitis J:293746
decreased T-helper 2 cell number J:293746
decreased T-helper 17 cell number J:293746
Pgam5tm1d(EUCOMM)Wtsi/Pgam5tm1d(EUCOMM)Wtsi
(involves: C57BL/6N)
abnormal interleukin-1 beta secretion J:240016
abnormal macrophage activation involved in immune response J:240016
decreased interleukin-1 beta secretion J:240016
Pgap3tm1.1Ymra/Pgap3tm1.1Ymra
(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:181221
abnormal T cell morphology J:181221
decreased T cell proliferation J:181221
immune system phenotype J:181221
increased susceptibility to experimental autoimmune encephalomyelitis J:181221
increased T cell proliferation J:181221
Pgap3tm1.1Ymra/Pgap3tm1.1Ymra
(B6.Cg-Pgap3tm1.1Ymra)
abnormal T-helper 2 cell differentiation J:203443
decreased B cell proliferation J:203443
immune system phenotype J:203443
impaired macrophage phagocytosis J:203443
increased anti-double stranded DNA antibody level J:203443
increased anti-single stranded DNA antibody level J:203443
increased spleen germinal center number J:203443
Pgap3tm1Ymra/Pgap3tm1Ymra
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd)
immune system phenotype J:203443
Pgap3tm1Ymra/Pgap3tm1Ymra
Tg(Lck-cre)#Jxm/0

(involves: C57BL/6 * CBA)
immune system phenotype J:203443
Pgap4em1Osbir/Pgap4em1Osbir
(involves: C57BL/6NSlc)
increased Ly6C-positive immature NK cell number J:333707
increased susceptibility to infection induced morbidity/mortality J:333707
increased susceptibility to prion infection J:333707
Pgbd1em1(IMPC)Tcp/Pgbd1em1(IMPC)Tcp
(C57BL/6NCrl-Pgbd1em1(IMPC)Tcp/Tcp)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Pgdtm1.1Pse/Pgdtm1.1Pse
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal alpha-beta T cell morphology J:306553
abnormal CD8-positive, alpha beta T cell morphology J:306553
abnormal CD8-positive, alpha-beta T cell physiology J:306553
abnormal T cell differentiation J:306553
decreased CD4-positive, alpha-beta T cell number J:306553
decreased CD8-positive, alpha-beta T cell number J:306553
Pgdtm1.1Pse/Pgdtm1.1Pse
Tg(Cd4-cre)1Cwi/0
Tg(TcraTcrb)8Rest/0

(involves: C57BL/6 * DBA/2)
abnormal CD8-positive, alpha-beta T cell physiology J:306553
Pgdtm1.1Pse/Pgdtm1.1Pse
Tg(Cd4-cre)1Cwi/0
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6 * DBA/2)
abnormal cytotoxic T cell physiology J:306553
Pgftm1Pec/Pgftm1Pec
(involves: 129)
decreased susceptibility to type IV hypersensitivity reaction J:81388
Pgia1BALB/cCrl/Pgia1DBA/2Crl
(involves: BALB/cCrl * DBA/2Crl)
increased autoantibody level J:66460
increased susceptibility to autoimmune disorder J:66460
Pgia2BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased autoantibody level J:66460
Pgia3DBA/2Crl/?
(involves: BALB/cCrl * DBA/2Crl)
increased autoantibody level J:66460
increased inflammatory response J:66460
Pgia4BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased autoantibody level J:66460
Pgia5BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased inflammatory response J:66460
Pgia6BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased autoantibody level J:66460
Pgia7BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased autoantibody level J:66460
Pgia8DBA/2/Pgia8DBA/2
(C.D2-(D15Mit12-D15Mit267))
decreased susceptibility to induced arthritis J:137478
Pgia8DBA/2/Pgia8DBA/2
(involves: BALB/c * DBA/2)
decreased interleukin-6 secretion J:137478
decreased susceptibility to induced arthritis J:137478
increased tumor necrosis factor secretion J:137478
Pgia8DBA/2Crl/?
(involves: BALB/cCrl * DBA/2Crl)
increased inflammatory response J:66460
Pgia9BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased inflammatory response J:66460
Pgia9DBA/2/Pgia9DBA/2
(C.D2-(D15Mit267-D15Mit41))
decreased susceptibility to induced arthritis J:137478
Pgia9DBA/2/Pgia9DBA/2
(involves: BALB/c * DBA/2)
decreased susceptibility to induced arthritis J:137478
increased interleukin-6 secretion J:137478
increased tumor necrosis factor secretion J:137478
Pgia10BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased autoantibody level J:66460
increased inflammatory response J:66460
Pgia11BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased autoantibody level J:66460
Pgia12BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased inflammatory response J:66460
Pgia13C3H/HeJCr/Pgia13C3H/HeJCr
(involves: C3H/HeJCr * C57BL/6)
increased susceptibility to induced arthritis J:65424
Pgia14C3H/HeJCr/Pgia14C3H/HeJCr
(involves: C3H/HeJCr * C57BL/6)
increased susceptibility to induced arthritis J:65424
Pgia15C3H/HeJCr/Pgia15C3H/HeJCr
(involves: C3H/HeJCr * C57BL/6)
increased susceptibility to induced arthritis J:65424
Pgia16C3H/HeJCr/Pgia16C3H/HeJCr
(involves: C3H/HeJCr * C57BL/6)
increased susceptibility to autoimmune disorder J:65424
Pgia26BALB/cCrl/?
(involves: BALB/cCrl * DBA/2Crl)
increased inflammatory response J:84150
Pgia26DBA/2Crl/?
(involves: BALB/cCrl * DBA/2Crl)
abnormal inflammatory response J:84150
Pgia39DBA/2Crl/?
Pgia6BALB/cCrl/Pgia6DBA/2Crl

(involves: BALB/cCrl * DBA/2Crl)
decreased inflammatory response J:84150
Pgia39DBA/2Crl/Pgia39DBA/2Crl
Pgia6DBA/2Crl/Pgia6DBA/2Crl

(involves: BALB/cCrl * DBA/2Crl)
increased susceptibility to induced arthritis J:84150
Pgia39DBA/2Crl/Pgia39DBA/2Crl
Pgia26BALB/cCrl/Pgia26BALB/cCrl

(involves: BALB/cCrl * DBA/2Crl)
increased susceptibility to induced arthritis J:84150
Pgis1DBA/2/Pgis1DBA/2
(involves: BALB/c * DBA/2)
increased susceptibility to induced arthritis J:107496
Pgis1DBA/2/Pgis1DBA/2
Pgis2BALB/c/Pgis2BALB/c

(involves: BALB/c * DBA/2)
increased susceptibility to induced arthritis J:107496
Pgis1DBA/2/Pgis1DBA/2
Pgis2BALB/c/Pgis2DBA/2

(involves: BALB/c * DBA/2)
increased susceptibility to induced arthritis J:107496
Pgis2BALB/c/Pgis2BALB/c
(involves: BALB/c * DBA/2)
increased susceptibility to induced arthritis J:107496
Pgis2BALB/c/Pgis2DBA/2
(involves: BALB/c * DBA/2)
increased susceptibility to induced arthritis J:107496
Pglyrp1tm1.1Lky/Pglyrp1tm1.1Lky
(B6.129S4-Pglyrp1tm1.1Lky)
abnormal neutrophil physiology J:171412
increased susceptibility to bacterial infection J:171412
Pglyrp1tm1Rdz/Pglyrp1tm1Rdz
(involves: 129S5/SvEvBrd)
abnormal neutrophil physiology J:84680
impaired granulocyte bactericidal activity J:84680
increased susceptibility to bacterial infection J:84680
increased susceptibility to bacterial infection induced morbidity/mortality J:84680
Pglyrp1tm1Rdz/Pglyrp1tm1Rdz
(C.129S-Pglyrp1tm1Rdz)
increased susceptibility to induced arthritis J:178054
Pglyrp1tm1Rdz/Pglyrp1tm1Rdz
(involves: 129S5/SvEvBrd * BALB/c)
abnormal chemokine secretion J:178053
increased interleukin-6 secretion J:178053
increased susceptibility to induced colitis J:178053
Pglyrp1tm1Rdz/Pglyrp1tm1Rdz
Pglyrp2tm1Rdz/Pglyrp2tm1Rdz

(C.129S-Pglyrp1tm1Rdz Pglyrp2tm1Rdz)
decreased susceptibility to induced arthritis J:178054
Pglyrp2tm1Lky/Pglyrp2tm1Lky
(involves: 129S4/SvJae * C57BL/6)
abnormal macrophage physiology J:159600
abnormal tumor necrosis factor level J:159600
decreased circulating interleukin-6 level J:159600
decreased susceptibility to bacterial infection induced morbidity/mortality J:159600
Pglyrp2tm1Rdz/Pglyrp2tm1Rdz
(C.129S-Pglyrp2tm1Rdz)
abnormal circulating chemokine level J:178054
decreased susceptibility to induced arthritis J:178054
Pglyrp2tm1Rdz/Pglyrp2tm1Rdz
(involves: 129S/SvEv * BALB/c)
abnormal chemokine secretion J:178053
increased interleukin-6 secretion J:178053
increased susceptibility to induced colitis J:178053
Pglyrp3tm1Rdz/Pglyrp3tm1Rdz
(C.129S-Pglyrp3tm1Rdz)
immune system phenotype J:178054
Pglyrp3tm1Rdz/Pglyrp3tm1Rdz
(involves: 129S6/SvEvTac * BALB/c)
abnormal chemokine secretion J:178053
increased interleukin-6 secretion J:178053
increased susceptibility to induced colitis J:178053
Pglyrp4em1(IMPC)Ccpcz/Pglyrp4em1(IMPC)Ccpcz
(C57BL/6NCrl-Pglyrp4em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
small thymus J:211773
Pglyrp4tm1Rdz/Pglyrp4tm1Rdz
(C.129S-Pglyrp4tm1Rdz)
immune system phenotype J:178054
Pglyrp4tm1Rdz/Pglyrp4tm1Rdz
(involves: 129S6/SvEvTac * BALB/c)
abnormal chemokine secretion J:178053
increased interleukin-6 secretion J:178053
increased susceptibility to induced colitis J:178053
Pgm3Gt(W037B08)Wrst/Pgm3mld1
(involves: 129S1/Sv * C57BL/6)
abnormal T cell differentiation J:125094
absent follicular B cells J:125094
decreased B cell number J:125094
decreased leukocyte cell number J:125094
decreased T cell number J:125094
glomerulonephritis J:125094
increased pro-B cell number J:125094
increased spleen red pulp amount J:125094
Pgm3mld1/Pgm3mld1
(C57BL/6-Pgm3mld1)
abnormal thrombopoiesis J:125094
absent follicular B cells J:125094
decreased B cell number J:125094
decreased leukocyte cell number J:125094
increased pro-B cell number J:125094
increased spleen red pulp amount J:125094
increased spleen weight J:125094
Pgrtm1Bwo/Pgrtm1Bwo
(either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6))
uterus inflammation J:28980
Pgrtm1Bwo/Pgrtm1Bwo
(involves: 129S7/SvEvBrd)
abnormal osteoclast morphology J:145383
Pgrtm1Lyd/Pgrtm1Lyd
(involves: 129S7/SvEvBrd)
abnormal cytokine secretion J:130208
Pgrtm2(cre)Lyd/Pgr+
Criptotm2.2Mms/Criptotm2.2Mms

(involves: 129/Sv * C57BL/6N * CD-1)
endometrium inflammation J:324146
Pgrmc1em1Ejho/Pgrmc1em1Ejho
(involves: C57BL/6N)
liver inflammation J:268130
Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp
Pgrtm2(cre)Lyd/Pgr+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
decreased uterine NK cell number J:247103
Phactr1em1(IMPC)Mbp/Phactr1em1(IMPC)Mbp
(C57BL/6NCrl-Phactr1em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased leukocyte cell number J:211773
enlarged lymph nodes J:211773
Phb1em1(IMPC)H/Phb1+
(C57BL/6NTac-Phb1em1(IMPC)H/H)
increased large unstained cell number J:211773
Phc1tm1Os/Phc1tm1Os
(involves: 129S2/SvPas * C57BL/6)
abnormal B cell differentiation J:75707
decreased spleen weight J:43764
decreased thymus weight J:43764
Phc2tm1Hko/Phc2tm1Hko
(B6.129-Phc2tm1Hko)
immune system phenotype J:100027
Phc3tm2b(KOMP)Wtsi/Phc3tm2b(KOMP)Wtsi
(C57BL/6N-Phc3tm2b(KOMP)Wtsi/Ucd)
decreased thymus weight J:211773
PhexHyp-Duk/Y
(involves: BALB/cAnBomUrd)
ear inflammation J:132678
increased susceptibility to otitis media J:132678
PhexHyp/?
(involves: C57BL/6J)
enthesitis J:192371
PhexMhdabap024/Y
(C3HeB/FeJ-PhexMhdabap024)
decreased circulating C-reactive protein level J:264682
PhexSka1/PhexSka1
(C57BL/6-PhexSka1)
abnormal osteoclast physiology J:79953
Phf6em1Wencc/Y
Tg(Vav1-cre)#Cgp/0

(Not Specified)
abnormal effector T cell number J:278804
abnormal splenic cell ratio J:278804
abnormal thymus cell ratio J:278804
decreased CD4-positive, alpha-beta T cell number J:278804
decreased CD8-positive, alpha-beta T cell number J:278804
decreased double-negative T cell number J:278804
decreased lymphocyte cell number J:278804
enlarged spleen J:278804
immune system phenotype J:278804
increased B cell number J:278804
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:278804
increased pro-B cell number J:278804
Phf6em1Wencc/Phf6em1Wencc
Tg(Vav1-cre)#Cgp/0

(Not Specified)
abnormal effector T cell number J:278804
abnormal splenic cell ratio J:278804
abnormal thymus cell ratio J:278804
decreased CD4-positive, alpha-beta T cell number J:278804
decreased CD8-positive, alpha-beta T cell number J:278804
decreased double-negative T cell number J:278804
decreased lymphocyte cell number J:278804
enlarged spleen J:278804
immune system phenotype J:278804
increased B cell number J:278804
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:278804
increased leukocyte cell number J:278804
increased pro-B cell number J:278804
Phf6tm1.1Avo/Y
Tg(Tek-cre)1Ywa/0

(involves: C57BL/6 * SJL)
abnormal T cell differentiation J:276228
decreased DN2 thymocyte number J:276228
increased circulating interferon-alpha level J:276228
increased plasmacytoid dendritic cell number J:276228
Phf8tm1dIcs/Phf8tm1dIcs
(C57BL/6N-Phf8tm1dIcs/Ics)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Phf11dm1H/Phf11dm1H
(C3H.CAnNCrl(C3)-Phf11dm1H)
abnormal inflammatory response J:217094
Phf19tm1.1Ldc/Phf19tm1.1Ldc
(Not Specified)
enlarged spleen J:313068
Phf20Gt(XN131)Byg/Phf20Gt(XN131)Byg
(involves: 129P2/OlaHsd)
abnormal T cell differentiation J:228714
decreased double-positive T cell number J:228714
decreased thymocyte number J:228714
increased double-negative T cell number J:228714
intermingled spleen red and white pulp J:228714
small spleen J:228714
small thymus J:228714
thymus hypoplasia J:228714
Phf20l1em1(IMPC)Tcp/Phf20l1em1(IMPC)Tcp
(C57BL/6N-Phf20l1em1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased spleen weight J:211773
Phipem1(IMPC)Wtsi/Phip+
(C57BL/6N-Phipem1(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Phka1em1(IMPC)Tcp/Y
(C57BL/6N-Phka1em1(IMPC)Tcp/Tcp)
small spleen J:211773
Phlda1tm1Ywc/Phlda1tm1Ywc
(involves: 129S1/Sv * C57BL/6J)
immune system phenotype J:72947
Phldb2em1(IMPC)H/Phldb2em1(IMPC)H
(C57BL/6NTac-Phldb2em1(IMPC)H/H)
increased basophil cell number J:211773
Phlpp1tm1.1Saco/Phlpp1tm1.1Saco
(involves: 129 * C57BL/6)
immune system phenotype J:231241
Phlpp1tm1.1Saco/Phlpp1tm1.1Saco
Phlpp2tm1d(EUCOMM)Hmgu/Phlpp2tm1d(EUCOMM)Hmgu

(involves: 129 * C57BL/6N)
decreased susceptibility to induced colitis J:231241
Phlpp2tm1d(EUCOMM)Hmgu/Phlpp2tm1d(EUCOMM)Hmgu
(involves: C57BL/6N)
immune system phenotype J:231241
Phrf1em1(IMPC)Tcp/Phrf1em1(IMPC)Tcp
(C57BL/6N-Phrf1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
small spleen J:211773
Phyhtm1b(EUCOMM)Wtsi/Phyhtm1b(EUCOMM)Wtsi
(C57BL/6N-Phyhtm1b(EUCOMM)Wtsi/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Phyhtm1Safe/Phyhtm1Safe
(involves: 129P2/OlaHsd * 129X1/SvJ * Black Swiss * FVB/N)
liver inflammation J:142512
Pi4kam1Btlr/Pi4kam1Btlr
(C57BL/6J-Pi4kam1Btlr)
decreased macrophage apoptosis J:265261
decreased tumor necrosis factor secretion J:265261
increased interleukin-1 beta secretion J:265261
Pi4kam2Btlr/Pi4kam2Btlr
(C57BL/6J-Pi4kam2Btlr)
increased alpha-beta T cell number J:272852
increased CD4-positive, alpha-beta T cell number J:272852
increased central memory CD4-positive, alpha-beta T cell number J:272852
Pi4katm1b(EUCOMM)Wtsi/Pi4ka+
(C57BL/6N-Pi4katm1b(EUCOMM)Wtsi/Tcp)
increased monocyte cell number J:211773
Pi4katm2.1Arte/Pi4ka+
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6NTac)
abnormal spleen morphology J:188779
Pi16em1(IMPC)Mbp/Pi16em1(IMPC)Mbp
(C57BL/6NCrl-Pi16em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Pi16Gt(OST292194)Lex/Pi16Gt(OST292194)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal lymph node B cell domain morphology J:94077
abnormal spleen germinal center morphology J:94077
increased regulatory T cell number J:94077
Pi16tm1.2Engl/Pi16tm1.2Engl
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * SJL)
abnormal immune system physiology J:244259
Pias1tm1Kes/Pias1tm1Kes
(involves: 129S/Sv * C57BL/6)
decreased susceptibility to Riboviria infection induced morbidity/mortality J:92167
increased susceptibility to bacterial infection induced morbidity/mortality J:92167
increased susceptibility to endotoxin shock J:92167
Pias4tm1Rug/Pias4tm1Rug
(involves: 129S2/SvPas * C57BL/6)
abnormal myelopoiesis J:94291
Picalmtm1.1Tmae/Picalmtm1.1Tmae
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * CBA * SJL)
decreased CD4-positive, alpha-beta T cell number J:220728
decreased CD8-positive, alpha-beta T cell number J:220728
Picalmtm1.1Tmae/Picalmtm1.1Tmae
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA * SJL)
decreased CD4-positive, alpha-beta T cell number J:220728
decreased CD8-positive, alpha-beta T cell number J:220728
enlarged spleen J:220728
Picalmtm1Towa/Picalmtm1Towa
(involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj)
abnormal B cell differentiation J:185312
decreased spleen B cell follicle number J:185312
enlarged spleen J:185312
Pierce1Gt(OST3440)Lex/Pierce1Gt(OST3440)Lex
(either: (involves: 129S5/SvEvBrd * C57BL/6J) or (involves: 129S5/SvEvBrd * C57BL/6J * FVB/N))
abnormal spleen morphology J:252050
Pierce1tm2b(EUCOMM)Wtsi/Pierce1tm2b(EUCOMM)Wtsi
(C57BL/6N-Pierce1tm2b(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Piezo1tm2.1Apat/Piezo1tm2.1Apat
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA)
abnormal spleen morphology J:229436
abnormal splenic cell ratio J:229436
Pigatm1Tak/Pigatm1Tak
Tg(FES-cre)31Bsl/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/Ca)
abnormal T cell activation J:162065
abnormal T cell morphology J:162065
abnormal T cell physiology J:162065
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:162065
Pignem1(IMPC)Mbp/Pign+
(C57BL/6N-Pignem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Pigrtm1Fejo/Pigrtm1Fejo
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immunoglobulin level J:57987
abnormal immunoglobulin transcytosis J:57987
decreased IgA level J:57987
increased IgA level J:57987
increased IgG level J:57987
Pigrtm1Fejo/Pigrtm1Fejo
(involves: 129 * C57BL/6)
increased IgA level J:140515
increased susceptibility to parasitic infection J:140515
Pigrtm1Ohw/Pigrtm1Ohw
(involves: 129X1/SvJ * C57BL/6J)
decreased IgA level J:58454
increased IgA level J:58454
increased IgE level J:58454
increased IgG level J:58454
Pigrtm1Ohw/Pigrtm1Ohw
(B6.129X1-Pigrtm1Ohw)
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:97824
abnormal intraepithelial T cell number J:97824
abnormal lymphocyte physiology J:97824
decreased IgA level J:108538
decreased interferon-gamma secretion J:108538
decreased tumor necrosis factor secretion J:108538
increased IgA level J:108538, J:97824
increased susceptibility to bacterial infection J:108538
Pigrtm1Ohw/Pigrtm1Ohw
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J)
decreased lymphocyte cell number J:97824
immune system phenotype J:97824
increased IgA level J:97824
Pigrtm1Rast/Pigrtm1Rast
(C57BL/6-Pigrtm1Rast)
abnormal immune system cell morphology J:81984
abnormal immunoglobulin level J:81984
abnormal immunoglobulin transcytosis J:81984
decreased IgA level J:81984
increased IgA level J:81984
increased IgG level J:81984
Pigvb2b2859Clo/Pigvb2b2859Clo
(C57BL/6J-Pigvb2b2859Clo)
thymus hypoplasia J:175213
Pik3ap1m1Btlr/Pik3ap1m1Btlr
(involves: C57BL/6J)
arrested B cell differentiation J:185495
decreased IgM level J:185495
immune system phenotype J:185495
Pik3ap1m2Btlr/Pik3ap1m2Btlr
(C57BL/6J-Pik3ap1m2Btlr)
decreased B-1a cell number J:255271
impaired humoral immune response J:255271
increased B-1b cell number J:255271
increased IgM level J:255271
Pik3ap1M3Btlr/Pik3ap1M3Btlr
(C57BL/6J-Pik3ap1M3Btlr)
decreased B-1 B cell number J:272019
Pik3ap1tm1b(KOMP)Wtsi/Pik3ap1tm1b(KOMP)Wtsi
(C57BL/6N-Pik3ap1tm1b(KOMP)Wtsi/Orl)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Pik3ap1tm1Kuro/Pik3ap1tm1Kuro
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:75075
absent B-1a cells J:84669
decreased B cell number J:84669
decreased B cell proliferation J:84669
decreased follicular B cell number J:84669
decreased IgG2b level J:75075
decreased IgG3 level J:75075
decreased IgM level J:75075
decreased immunoglobulin level J:75075
decreased pre-B cell number J:75075
spleen hypoplasia J:75075
Pik3c2aGt(OST288105)Lex/Pik3c2aGt(OST288105)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
enlarged spleen J:169710
glomerulonephritis J:169710
immune system phenotype J:169710
increased anti-double stranded DNA antibody level J:169710
increased B cell number J:169710
increased CD4-positive, alpha-beta T cell number J:169710
increased CD8-positive, alpha-beta T cell number J:169710
increased granulocyte number J:169710
increased IgA level J:169710
increased IgG level J:169710
increased IgM level J:169710
increased leukocyte cell number J:169710
increased monocyte cell number J:169710
increased neutrophil cell number J:169710
Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
(C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp)
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased neutrophil cell number J:211773
Pik3c2atm1Bvan/Pik3c2a+
(involves: C57BL/6)
abnormal thrombopoiesis J:226344
Pik3c3tm1.1Flv/Pik3c3tm1.1Flv
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * C57BL/6N * DBA/2)
abnormal T cell number J:184753
decreased CD4-positive, alpha-beta T cell number J:184753
decreased CD8-positive, alpha-beta T cell number J:184753
Pik3c3tm1.1Flv/Pik3c3tm1.1Flv
Tg(Cd8a-cre)1Itan/0

(involves: C57BL/6 * C57BL/6N)
abnormal CD4-positive, alpha beta T cell morphology J:184753
abnormal CD8-positive, alpha beta T cell morphology J:184753
decreased CD4-positive, alpha-beta T cell number J:184753
decreased CD8-positive, alpha-beta T cell number J:184753
decreased lymphocyte cell number J:184753
immune system phenotype J:184753
increased T cell apoptosis J:184753
Pik3catm1Jdo/Pik3catm1Jdo
(B6.129S7(Cg)-Pik3catm1Jdo)
abnormal lymphangiogenesis J:122866
abnormal lymphatic vessel morphology J:122866
Pik3cdGt(OST451938)Lex/Pik3cdGt(OST451938)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased IgG1 level J:103485
increased leukocyte cell number J:103485
increased lymphocyte cell number J:103485
Pik3cdm1Btlr/Pik3cdm1Btlr
(C57BL/6J-Pik3cdm1Btlr)
abnormal humoral immune response J:213049
Pik3cdm2Btlr/Pik3cd+
(C57BL/6J-Pik3cdm2Btlr)
decreased B-1 B cell number J:236693
decreased IgG level J:236693
decreased IgM level J:236693
decreased response to antigen J:236693
Pik3cdm2Btlr/Pik3cdm2Btlr
(C57BL/6J-Pik3cdm2Btlr)
decreased B-1 B cell number J:236693
decreased B-1a cell number J:236693
decreased IgG level J:236693
decreased IgM level J:236693
decreased response to antigen J:236693
increased circulating interferon-alpha level J:236693
increased IgE level J:236693
increased response to antigen J:236693
increased susceptibility to Herpesvirales infection J:236693
Pik3cdtm1.1Bvan/Pik3cdtm1.1Bvan
(involves: 129P2/OlaHsd * BALB/c)
abnormal B cell differentiation J:78412
abnormal Peyer's patch germinal center morphology J:78412
absent spleen germinal center J:78412
decreased B-1 B cell number J:78412
decreased IgA level J:78412
decreased IgM level J:78412
decreased immunoglobulin level J:78412
increased neutrophil cell number J:78412
intestinal inflammation J:78412
spleen hypoplasia J:78412
Pik3cdtm1Jni/Pik3cdtm1Jni
(involves: 129P2/OlaHsd)
abnormal B cell physiology J:80614
abnormal humoral immune response J:80614
absent B-1 B cells J:80614
absent spleen germinal center J:80614
decreased B cell number J:80614
decreased B cell proliferation J:80614
decreased immunoglobulin level J:80614
decreased mature B cell number J:80614
small lymph nodes J:80614
small spleen J:80614
Pik3cdtm1Jni/Pik3cdtm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:124330
Pik3cdtm1Jni/Pik3cdtm1Jni
Pik3cgtm1Pngr/Pik3cgtm1Pngr

(involves: 129P2/OlaHsd * C57BL/6)
abnormal NK cell differentiation J:124330
decreased cytotoxic T cell cytolysis J:124330
decreased interferon-gamma secretion J:124330
decreased NK cell number J:124330
decreased T cell number J:124330
spleen hypoplasia J:124330
Pik3cdtm1Tnr/Pik3cdtm1Tnr
(involves: 129S4/SvJae)
abnormal B cell physiology J:113491
abnormal humoral immune response J:79133
decreased B cell number J:79133
decreased B cell proliferation J:113491, J:79133
decreased B-1 B cell number J:79133
decreased B-2 B cell number J:79133
decreased IgG1 level J:79133
decreased IgG2a level J:79133
decreased IgG2b level J:79133
decreased IgG3 level J:79133
decreased IgM level J:79133
decreased marginal zone B cell number J:79133
Pik3cdtm1Tnr/Pik3cdtm1Tnr
(B6.129S4-Pik3cdtm1Tnr)
decreased inflammatory response J:134324
decreased susceptibility to induced arthritis J:134324
Pik3cdtm1Tnr/Pik3cdtm1Tnr
Pik3cgtm1Pngr/Pik3cgtm1Pngr

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal T cell differentiation J:125791
abnormal T cell physiology J:125791
abnormal thymus lobule morphology J:125791
decreased CD4-positive, alpha-beta T cell number J:125791
decreased CD8-positive, alpha-beta T cell number J:125791
decreased double-positive T cell number J:125791
decreased lymphocyte cell number J:125791
decreased T cell number J:125791
small thymus J:125791
thymus hypoplasia J:125791
Pik3cdtm1Tnr/Pik3cdtm1Tnr
Pik3cgtm1Pngr/Pik3cgtm1Pngr

(B6.129-Pik3cdtm1Tnr Pik3cgtm1Pngr)
decreased inflammatory response J:134324
decreased susceptibility to induced arthritis J:134324
impaired neutrophil chemotaxis J:134324
impaired neutrophil recruitment J:134324
Pik3cdtm1Tnr/Pik3cdtm1Tnr
Ptentm2.1Ppp/Ptentm2.1Ppp
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJae * C57BL/6)
abnormal class switch recombination J:130950
immune system phenotype J:130950
increased marginal zone B cell number J:130950
Pik3cdtm1Tnr/Pik3cdtm1Tnr
Tg(BCL2)36Wehi/0

(involves: 129S4/SvJae * C57BL/6JWehi * SJL/JWehi)
decreased follicular B cell number J:130950
Pik3cdtm2.1Tnr/Pik3cdtm2.1Tnr
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:164283
increased IgE level J:164283
Pik3cdtm2.1Tnr/Pik3cdtm2.1Tnr
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal adaptive immunity J:164283
abnormal humoral immune response J:164283
decreased CD4-positive, alpha-beta T cell number J:164283
decreased CD8-positive, alpha-beta T cell number J:164283
decreased germinal center B cell number J:164283
decreased IgG1 level J:164283
decreased spleen germinal center number J:164283
decreased spleen germinal center size J:164283
decreased T cell number J:164283
decreased T follicular helper cell number J:164283
Pik3cdtm2.1Tnr/Pik3cdtm2.1Tnr
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6)
abnormal humoral immune response J:164283
decreased germinal center B cell number J:164283
decreased IgG1 level J:164283
decreased spleen germinal center number J:164283
decreased T follicular helper cell number J:164283
Pik3cgtm1Dwu/Pik3cgtm1Dwu
(Not Specified)
decreased immunoglobulin level J:60348
impaired neutrophil chemotaxis J:60348
Pik3cgtm1Dwu/Pik3cgtm1Dwu
(B6.Cg-Pik3cgtm1Dwu)
abnormal CD8-positive, alpha-beta T cell physiology J:131923
abnormal response to infection J:131923
decreased CD8-positive, alpha-beta T cell number J:131923
immune system phenotype J:131923
increased susceptibility to Poxviridae infection J:131923
Pik3cgtm1Dwu/Pik3cgtm1Dwu
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6)
abnormal CD8-positive, alpha-beta T cell physiology J:131923
abnormal response to infection J:131923
immune system phenotype J:131923
Pik3cgtm1Ehi/Pik3cgtm1Ehi
(Not Specified)
impaired macrophage chemotaxis J:91945
impaired neutrophil recruitment J:91945
Pik3cgtm1Lste/Pik3cgtm1Lste
(involves: 129P2/OlaHsd * C57BL/6)
abnormal neutrophil physiology J:147259
impaired neutrophil chemotaxis J:147259
impaired neutrophil recruitment J:147259
Pik3cgtm1Lste/Pik3cgtm1Lste
(involves: 129P2/OlaHsd)
impaired neutrophil chemotaxis J:238900
Pik3cgtm1Pngr/Pik3cgtm1Pngr
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune cell physiology J:60347
abnormal neutrophil physiology J:60347
abnormal NK cell differentiation J:124330
abnormal T cell activation J:60347
abnormal T cell differentiation J:60347
abnormal T cell physiology J:60347
abnormal T-helper 2 physiology J:60347
decreased CD4-positive, alpha-beta T cell number J:60347
decreased cytotoxic T cell cytolysis J:124330
decreased interferon-gamma secretion J:60347, J:124330
decreased interleukin-2 secretion J:60347
decreased T cell proliferation J:60347
decreased thymocyte number J:60347
impaired neutrophil chemotaxis J:60347
impaired neutrophil recruitment J:60347
increased eosinophil cell number J:60347
increased monocyte cell number J:60347
increased neutrophil cell number J:60347
thymus hypoplasia J:60347
Pik3cgtm1Pngr/Pik3cgtm1Pngr
(B6.129P2-Pik3cgtm1Pngr)
decreased inflammatory response J:134324
decreased susceptibility to induced arthritis J:134324
impaired neutrophil chemotaxis J:134324
Pik3cgtm1Wym/Pik3cgtm1Wym
(either: 129/Sv-Pik3cgtm1Wym or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
abnormal leukocyte physiology J:60349
abnormal neutrophil physiology J:60349
impaired macrophage chemotaxis J:60349
impaired neutrophil chemotaxis J:60349
impaired neutrophil recruitment J:60349
increased neutrophil cell number J:60349
increased susceptibility to bacterial infection J:60349
Pik3cgtm1Wym/Pik3cgtm1Wym
(involves: 129S1/Sv * 129X1/SvJ)
abnormal neutrophil physiology J:147259
impaired neutrophil chemotaxis J:238900
impaired neutrophil recruitment J:147259
Pik3cgtm2Ehi/Pik3cgtm2Ehi
(Not Specified)
abnormal inflammatory response J:124856
abnormal macrophage physiology J:124856
decreased macrophage cell number J:124856
decreased neutrophil cell number J:124856
impaired macrophage chemotaxis J:124856
impaired neutrophil chemotaxis J:124856
increased interleukin-1 beta secretion J:124856
increased interleukin-6 secretion J:124856
increased leukocyte cell number J:124856
increased tumor necrosis factor secretion J:124856
Pik3ip1m1Anu/Pik3ip1m1Anu
(C57BL/6NCrlAnu-Pik3ip1m1Anu)
immune system phenotype J:104190
Pik3r1m1Btlr/Pik3r1m1Btlr
(C57BL/6J-Pik3r1m1Btlr)
decreased B cell number J:254890
decreased B-1a cell number J:254890
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254890
increased CD8-positive, alpha-beta memory T cell number J:254890
Pik3r1M2Btlr/Pik3r1+
(C57BL/6J-Pik3r1M2Btlr)
decreased B-1 B cell number J:254892
decreased B-1a cell number J:254892
decreased B-1b cell number J:254892
decreased B-2 B cell number J:254892
decreased NK T cell number J:254892
increased B-1b cell number J:254892
Pik3r1m3Btlr/Pik3r1m3Btlr
(C57BL/6J-Pik3r1m3Btlr)
increased B-1b cell number J:272853
Pik3r1tm1Dfr/Pik3r1tm1Dfr
(involves: 129S6/SvEvTac * C57BL/6)
arrested B cell differentiation J:52229
decreased B cell proliferation J:52229
decreased mature B cell number J:52229
Pik3r1tm1Dfr/Pik3r1tm1Dfr
(involves: 129S6/SvEvTac)
abnormal B cell differentiation J:104166
decreased immature B cell number J:104166
decreased mature B cell number J:104166
decreased pre-B cell number J:104166
increased pro-B cell number J:104166
Pik3r1tm1Dfr/Pik3r1tm1Dfr
Plcg2tm1Jni/Plcg2tm1Jni

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
abnormal B cell differentiation J:104166
arrested B cell differentiation J:104166
decreased immature B cell number J:104166
decreased mature B cell number J:104166
decreased pre-B cell number J:104166
immune system phenotype J:104166
increased B cell apoptosis J:104166
Pik3r1tm1Tka/Pik3r1tm1Tka
(involves: C57BL/6 * CBA)
abnormal B cell physiology J:113491
abnormal humoral immune response J:52228
decreased B cell number J:52228
decreased B cell proliferation J:113491, J:52228
decreased mature B cell number J:52228
decreased pre-B cell number J:52228
decreased pro-B cell number J:52228
increased susceptibility to bacterial infection J:52228
Pik3r1tm2Dfr/Pik3r1tm2Dfr
(either: C.129S6-Pik3r1tm2Dfr or (involves: 129S6/SvEvTac * BALB/c * C57BL/6))
abnormal B cell differentiation J:94077
Pik3r4tm1.1Mpnd/Pik3r4tm1.1Mpnd
Tg(ACTA1-cre)79Jme/0

(involves: 129S2/SvPas * C57BL/6J * C57BL/6N * SJL)
myositis J:198770
Pik3r5tm1Lste/Pik3r5tm1Lste
(involves: 129P2/OlaHsd * C57BL/6)
impaired neutrophil chemotaxis J:147259
impaired neutrophil recruitment J:147259
Pik3r5tm1Lste/Pik3r5tm1Lste
(involves: 129P2/OlaHsd)
impaired neutrophil chemotaxis J:238900
increased neutrophil cell number J:238900
Pik3r6tm1.1Lste/Pik3r6tm1.1Lste
(Not Specified)
abnormal neutrophil physiology J:238900
decreased granulocyte number J:238900
decreased lymphocyte cell number J:238900
immune system phenotype J:238900
increased neutrophil cell number J:238900
PikfyveGt(AT0926)Wtsi/PikfyveGt(AT0926)Wtsi
(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:190368
abnormal thymus morphology J:190368
spleen hypoplasia J:190368
thymus hypoplasia J:190368
Pikfyvetm2.1Tssk/Pikfyvetm2.1Tssk
Tg(Vil1-cre)20Syr/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
intestinal inflammation J:193689
Pilratm1Osb/Pilratm1Osb
(B6.129-Pilratm1Osb)
abnormal leukocyte adhesion J:191085
abnormal neutrophil physiology J:191085
increased neutrophil cell number J:191085
increased susceptibility to bacterial infection induced morbidity/mortality J:191085
increased susceptibility to endotoxin shock J:191085
Pilrb1tm1Pgh/Pilrb1tm1Pgh
(involves: C57BL/6)
abnormal chemokine level J:157763
abnormal cytokine level J:157763
abnormal cytokine secretion J:157763
decreased circulating interleukin-1 beta level J:157763
decreased circulating interleukin-6 level J:157763
decreased circulating tumor necrosis factor level J:157763
decreased interleukin-1 beta secretion J:157763
decreased susceptibility to bacterial infection J:157763
decreased susceptibility to bacterial infection induced morbidity/mortality J:157763
decreased tumor necrosis factor secretion J:157763
increased circulating interferon-gamma level J:157763
increased circulating interleukin-12 level J:157763
increased interferon-gamma secretion J:157763
increased interleukin-10 secretion J:157763
increased interleukin-12 secretion J:157763
Pim1tm1Pwl/Pim1tm1Pwl
(involves: 129P2/OlaHsd * BALB/c)
abnormal mast cell physiology J:15259, J:14715
Pim1tm1Pwl/Pim1tm1Pwl
Pim2tm1Brn/Pim2tm1Brn
Pim3tm1Brn/Pim3tm1Brn

(involves: 129P/Ola * FVB/N)
decreased B cell number J:91592
decreased B cell proliferation J:91592
decreased pre-B cell number J:91592
decreased pro-B cell number J:91592
decreased T cell proliferation J:91592
increased early pro-B cell number J:91592
Pim2tm1.1Lex/Pim2tm1.1Lex
(involves: 129S/SvEvBrd * C57BL/6)
decreased interleukin-6 secretion J:166403
Pim2tm1Brn/Pim2tm1Brn
(involves: 129P/Ola * FVB/N)
decreased T cell proliferation J:91592
Pink1tm1Hbu/Pink1tm1Hbu
(involves: 129S7/SvEvBrd * C57BL/6)
increased interleukin-1 beta secretion J:169471
increased interleukin-10 secretion J:169471
increased interleukin-12 secretion J:169471
Pip4k2ctm1b(KOMP)Wtsi/Pip4k2ctm1b(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
abnormal circulating chemokine level J:234283
abnormal T cell activation J:234283
chronic inflammation J:234283
chronic liver inflammation J:234283
decreased regulatory T cell number J:234283
increased CD4-positive, alpha-beta T cell number J:234283
increased CD8-positive, alpha-beta T cell number J:234283
increased circulating interferon-gamma level J:234283
increased circulating interleukin-2 level J:234283
increased circulating interleukin-4 level J:234283
increased circulating interleukin-10 level J:234283
increased circulating interleukin-12 level J:234283
increased circulating interleukin-12b level J:234283
increased IgG3 level J:234283
increased inflammatory response J:234283
increased interferon-gamma secretion J:234283
increased interleukin-17 secretion J:234283
increased T cell proliferation J:234283
increased T-helper cell number J:234283
intestinal inflammation J:234283
kidney inflammation J:234283
lung inflammation J:234283
salivary gland inflammation J:234283
Pip4p1em1(IMPC)Ccpcz/Pip4p1em1(IMPC)Ccpcz
(C57BL/6N-Pip4p1em1(IMPC)Ccpcz/Ccpcz)
increased CD4-negative, CD25-positive NK T cell number J:211773
Pip5k1btm1Tssk/Pip5k1btm1Tssk
(involves: 129P2/OlaHsd * C57BL/6)
abnormal mast cell physiology J:97991
increased susceptibility to type I hypersensitivity reaction J:97991
Pip5k1ctm1.2Ref/Pip5k1ctm1.2Ref
Tg(TcraTcrb)425Cbn/0

(involves: BALB/c * C57BL/6)
abnormal T cell physiology J:164732
decreased B cell number J:164732
decreased dendritic cell number J:164732
increased interferon-gamma secretion J:164732
increased interleukin-2 secretion J:164732
increased T cell proliferation J:164732
Piptm1Myal/Piptm1Myal
(involves: 129S/SvEv * C57BL/6)
abnormal thymus corticomedullary boundary morphology J:202016
arteritis J:202016
colitis J:202016
enlarged submandibular lymph nodes J:202016
enlarged thymus J:202016
enlarged thymus medulla J:202016
Pirbem1Fgla/Pirbem1Fgla
(C57BL/6-Pirbem1Fgla)
decreased length of allograft survival J:290663
Pirbtm1Ttk/Pirbtm1Ttk
(involves: 129X1/SvJ)
abnormal B cell physiology J:76770
abnormal dendritic cell differentiation J:76770
abnormal immune system cell morphology J:76770
abnormal leukocyte physiology J:76770
abnormal T cell physiology J:76770
abnormal T-helper 2 physiology J:76770
increased B cell proliferation J:76770
increased B-1 B cell number J:76770
Pitm1C57BL/FaDk/Pitm1C57BL/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:70033
Pitm1C57BL/FaDk/Pitm1RIII/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:70033
Pitm2C57BL/FaDk/Pitm2C57BL/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:70033
Pitm2C57BL/FaDk/Pitm2RIII/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:70033
Pitm3C57BL/FaDk/Pitm3C57BL/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:70033
Pitm3C57BL/FaDk/Pitm3RIII/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:70033
Pitm4C57BL/FaDk/Pitm4C57BL/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:70033
Pitm4C57BL/FaDk/Pitm4RIII/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:70033
Pitpnm1tm1a(EUCOMM)Wtsi/Pitpnm1tm1a(EUCOMM)Wtsi
(involves: C57BL/6N)
decreased leukocyte cell number J:207051
Pitx2tm1Hmd/Pitx2tm1Hmd
(involves: C3H * C57BL/6 * C57BL/6J)
small spleen J:128475
Pitx2tm1Jfm/Pitx2tm1Jfm
(involves: 129S4/SvJaeSor)
spleen hypoplasia J:57674
Pitx2tm1Rsd/Pitx2tm1Rsd
(involves: 129S1/Sv * 129X1/SvJ)
abnormal spleen morphology J:57673
Pitx2tm3.1Jfm/Pitx2tm3.1Jfm
(involves: 129S4/SvJaeSor)
small spleen J:92872
Pitx3eyl/Pitx3eyl
(involves: C3H/He * C57BL/6)
abnormal immunoglobulin level J:156878
decreased IgG3 level J:156878
decreased IgM level J:156878
decreased leukocyte cell number J:156878
increased CD4-positive, alpha-beta T cell number J:156878
increased CD8-positive, alpha-beta T cell number J:156878
increased granulocyte number J:156878
Pitx3tm1.1Cai/Pitx3+
Tg(tetO-SNCA*A53T)E2Cai/0

(involves: 129 * C57BL/6J * FVB/N)
microgliosis J:185958
Pja2tm1.2Afel/Pja2tm1.2Afel
(involves: 129S6/SvEvTac * C57BL/6J)
kidney inflammation J:345592
Pja2tm1b(EUCOMM)Wtsi/Pja2+
(C57BL/6N-Pja2tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Pja2tm1b(EUCOMM)Wtsi/Pja2tm1b(EUCOMM)Wtsi
(C57BL/6N-Pja2tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Pkd1tm1b(EUCOMM)Hmgu/Pkd1+
(C57BL/6N-Pkd1tm1b(EUCOMM)Hmgu/Bay)
increased neutrophil cell number J:211773
Pkd1tm1Djmp/Pkd1tm1Djmp
(involves: 129P2/OlaHsd * C57BL/6)
kidney inflammation J:94582
Pkd1tm1Jzh/Pkd1+
(either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129S4/SvJae * BALB/c))
bile duct inflammation J:52573
kidney inflammation J:52573
Pkd1l2tm1b(KOMP)Mbp/Pkd1l2tm1b(KOMP)Mbp
(C57BL/6N-Pkd1l2tm1b(KOMP)Mbp/H)
increased large unstained cell number J:211773
Pkd2tm1Dwo/Pkd2tm1Dwo
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
absent spleen J:77401
Pkhd1tm1.1Ggg/Pkhd1tm1.1Ggg
(involves: 129S/SvEv * 129S4/SvJae * C57BL/6)
bile duct inflammation J:125113
Pkhd1tm1Som/Pkhd1tm1Som
(involves: 129S/SvEv * C57BL/6)
enlarged spleen J:131370
Pklrchar4/Pklrchar4
(involves: A/J * C57BL/6)
decreased susceptibility to parasitic infection J:141722, J:86735
decreased susceptibility to parasitic infection induced morbidity/mortality J:141722
enlarged spleen J:86735
Pklrslc/Pklrslc
(CBA/NSlc-Pklrslc)
decreased susceptibility to parasitic infection J:141722
decreased susceptibility to parasitic infection induced morbidity/mortality J:141722
enlarged spleen J:30035
increased susceptibility to bacterial infection induced morbidity/mortality J:128518
Pkn1tm1b(KOMP)Wtsi/Pkn1tm1b(KOMP)Wtsi
(C57BL/6N-Pkn1tm1b(KOMP)Wtsi/H)
decreased large unstained cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
Pkn1tm1Kik/Pkn1tm1Kik
(B6.129P2-Pkn1tm1Kik)
abnormal germinal center B cell physiology J:193187
abnormal somatic hypermutation frequency J:193187
decreased activation-induced B cell apoptosis J:193187
glomerulonephritis J:193187
immune system phenotype J:193187
increased anti-double stranded DNA antibody level J:193187
increased B cell proliferation J:193187
increased germinal center B cell number J:193187
increased IgG1 level J:193187
increased IgG2a level J:193187
increased IgG2b level J:193187
increased IgM level J:193187
increased spleen germinal center size J:193187
increased splenocyte number J:193187
Pkn3tm1.1Mrl/Pkn3+
Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA/J)
enlarged spleen J:216983
enlarged thymus J:216983
Pkn3tm1.1Mrl/Pkn3tm1.1Mrl
Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA/J)
enlarged spleen J:216983
enlarged thymus J:216983
Pknox1Gt(OST71835)Lex/Pknox1Gt(OST71835)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
decreased single-positive T cell number J:103769
increased double-negative T cell number J:103769
increased T cell apoptosis J:103769
thymus hypoplasia J:103769
Pknox1tm1Ngc/Pknox1+
Tg(IghMyc)22Bri/0

(involves: C57BL * SJL)
decreased B cell apoptosis J:192251
increased B cell proliferation J:192251
Pknox1tm2.1Fbla/Pknox1tm2.1Fbla
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd)
decreased pre-B cell number J:192251
increased pro-B cell number J:192251
Pknox2em1(IMPC)Ccpcz/Pknox2em1(IMPC)Ccpcz
(C57BL/6N-Pknox2em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
small spleen J:211773
Pkp3tm1.1Fvr/Pkp3tm1.1Fvr
(involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL)
dermatitis J:136451
enlarged lymph nodes J:136451
Pla1aem1Appsc/Pla1aem1Appsc
(C57BL/6J-Pla1aem1Appsc)
abnormal interleukin level J:333902
decreased susceptibility to chemically induced skin inflammation J:333902
decreased susceptibility to induced arthritis J:333902
increased lymphocyte cell number J:333902
Pla2g2dtm1.1(KOMP)Vlcg/Pla2g2dtm1.1(KOMP)Vlcg
(C57BL/6N-Pla2g2dtm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Pla2g2dtm1.1Mhg/Pla2g2dtm1.1Mhg
(B6.Cg-Pla2g2dtm1.1Mhg)
immune system phenotype J:197334
Pla2g2dtm1.1Mhg/Pla2g2dtm1.1Mhg
(B6NCrSlc.Cg-Pla2g2dtm1.1Mhg)
abnormal cytotoxic T cell physiology J:229035
abnormal dendritic cell migration J:229035
abnormal dendritic cell physiology J:201008
abnormal effector T cell morphology J:201008
decreased interleukin-6 secretion J:201008
decreased susceptibility to Coronaviridae infection J:229035
decreased susceptibility to Coronaviridae infection induced morbidity/mortality J:229035
decreased tumor necrosis factor secretion J:201008
immune system phenotype J:201008
increased CD4-positive, alpha-beta T cell number J:229035, J:201008
increased CD8-positive, alpha-beta T cell number J:229035
increased dendritic cell number J:201008
increased interferon-gamma secretion J:229035
increased susceptibility to type IV hypersensitivity reaction J:201008
Pla2g2etm1Mhg/Pla2g2etm1Mhg
(B6.Cg-Pla2g2etm1Mhg)
immune system phenotype J:197334
Pla2g2ftm1Mhg/Pla2g2ftm1Mhg
(B6.Cg-Pla2g2ftm1Mhg)
immune system phenotype J:197334
Pla2g3tm1Murm/Pla2g3tm1Murm
(involves: 129S/SvEv * C57BL/6)
abnormal mast cell differentiation J:197334
abnormal mast cell morphology J:197334
decreased mast cell degranulation J:197334
decreased susceptibility to type I hypersensitivity reaction J:197334
ear inflammation J:197334
Pla2g4atm1Jvb/Pla2g4atm1Jvb
(involves: 129S4/SvJae)
abnormal mast cell differentiation J:54619
increased mast cell degranulation J:54619
Pla2g4atm1Jvb/Pla2g4atm1Jvb
(involves: 129S4/SvJae * BALB/c)
immune system phenotype J:110309
Pla2g4atm1Tksh/Pla2g4atm1Tksh
(involves: 129P2/OlaHsd * C57BL/6J)
increased susceptibility to type I hypersensitivity reaction J:39254
Pla2g4atm1Tksh/Pla2g4atm1Tksh
(NOD.129P2(B6)-Pla2g4atm1Tksh)
abnormal macrophage physiology J:99775
insulitis J:99775
Pla2g4atm1Tksh/Pla2g4atm1Tksh
(B6.129P2-Pla2g4atm1Tksh)
abnormal cytokine level J:107430
decreased interferon-gamma secretion J:107430
decreased susceptibility to experimental autoimmune encephalomyelitis J:107430
decreased tumor necrosis factor secretion J:107430
immune system phenotype J:197334
Pla2g4eem1Murm/Pla2g4eem1Murm
(C57BL/6NSlc-Pla2g4eem1Murm)
increased susceptibility to chemically induced skin inflammation J:333700
Pla2g5tm1Jarm/Pla2g5tm1Jarm
(involves: 129 * C57BL/6J)
abnormal macrophage physiology J:89490
decreased acute inflammation J:89490
Pla2g5tm1Jarm/Pla2g5tm1Jarm
(involves: 129 * BALB/c)
impaired macrophage phagocytosis J:110309
Pla2g5tm1Jarm/Pla2g5tm1Jarm
(C.129-Pla2g5tm1Jarm)
impaired macrophage phagocytosis J:110309
Pla2g5tm1Jarm/Pla2g5tm1Jarm
(involves: 129 * C57BL/6)
impaired macrophage phagocytosis J:110309
Pla2g5tm1Jarm/Pla2g5tm1Jarm
(B6.129-Pla2g5tm1Jarm)
immune system phenotype J:197334
impaired macrophage phagocytosis J:110309
Pla2g6m1Sein/Pla2g6m1Sein
(C57BL/6JJcl-Pla2g6m1Sein)
decreased double-positive T cell number J:155328
Pla2g7tm1.1Mcap/Pla2g7tm1.1Mcap
(B6.Cg-Pla2g7tm1.1Mcap)
decreased susceptibility to bacterial infection induced morbidity/mortality J:228564
increased susceptibility to bacterial infection J:228564
Pla2g10Gt712Lex/Pla2g10Gt712Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal interleukin level J:125607
decreased CD4-positive, alpha-beta T cell number J:125607
decreased CD8-positive, alpha-beta T cell number J:125607
decreased eosinophil cell number J:125607
decreased IgE level J:125607
decreased inflammatory response J:125607
decreased T cell number J:125607
Pla2g10tm1Kiku/Pla2g10tm1Kiku
(B6.129P2-Pla2g10tm1Kiku)
abnormal neutrophil physiology J:155082
decreased neutrophil cell number J:155082
immune system phenotype J:197334
impaired neutrophil chemotaxis J:155082
Pla2g15tm1.1Jash/Pla2g15tm1.1Jash
(involves: 129S1/Sv * C57BL/6)
abnormal macrophage morphology J:111561
abnormal macrophage physiology J:111561
abnormal spleen morphology J:111561
increased macrophage cell number J:111561
increased macrophage derived foam cell number J:111561
increased spleen weight J:111561
Pla2r1tm1Itoh/Pla2r1tm1Itoh
(involves: 129P2/OlaHsd * C57BL/6)
decreased susceptibility to endotoxin shock J:44868
Plaat3em1(IMPC)Tcp/Plaat3em1(IMPC)Tcp
(C57BL/6NCrl-Plaat3em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Plaat5em1(IMPC)Tcp/Plaat5em1(IMPC)Tcp
(C57BL/6N-Plaat5em1(IMPC)Tcp/Tcp)
increased eosinophil cell number J:211773
Plac8tm1Bhk/Plac8tm1Bhk
(involves: 129S6/SvEvTac * C57BL/6)
abnormal neutrophil physiology J:145277
Plac8tm1Bhk/Plac8tm1Bhk
(129S/SvEv-Plac8tm1Bhk)
abnormal neutrophil physiology J:145277
increased leukocyte cell number J:145277
increased neutrophil cell number J:145277
increased susceptibility to bacterial infection J:145277
Plac9tm1b(EUCOMM)Hmgu/Plac9tm1b(EUCOMM)Hmgu
(C57BL/6N-Plac9tm1b(EUCOMM)Hmgu/H)
decreased neutrophil cell number J:211773
Plag1em1(IMPC)Hmgu/Plag1em1(IMPC)Hmgu
(C57BL/6N-Plag1em1(IMPC)Hmgu/Ieg)
decreased CD8-positive, naive alpha-beta T cell number J:211773
Plattm1Mlg/Plattm1Mlg
(involves: 129S2/SvPas * C57BL/6)
abnormal acute phase protein level J:63134, J:82604
immune system phenotype J:17427
increased macrophage cell number J:63134
Plattm1Mlg/Plattm1Mlg
(B6.Cg-Plattm1Mlg)
abnormal acute phase protein level J:75303
abnormal cytokine level J:75303
arthritis J:75303
chronic joint inflammation J:75303
Plattm1Mlg/Plattm1Mlg
(involves: 129S2/SvPas)
abnormal microglial cell physiology J:144185
Plattm1Mlg/Plattm1Mlg
(B6.129S2-Plattm1Mlg/J)
abnormal susceptibility to Coronaviridae infection J:288556
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:288556
Plautm1.1Bug/Plautm1.1Bug
(involves: C57BL/6)
chronic inflammation J:164542
liver inflammation J:164542
trachea inflammation J:164542
Plautm1b(EUCOMM)Wtsi/Plautm1b(EUCOMM)Wtsi
(C57BL/6N-Plautm1b(EUCOMM)Wtsi/H)
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Plautm1Mlg/Plautm1Mlg
(involves: 129S2/SvPas * C57BL/6)
abnormal acute phase protein level J:63134, J:82604
abnormal cell-mediated immunity J:87817, J:95638
abnormal macrophage physiology J:17427
abnormal neutrophil physiology J:75573, J:91980
impaired granulocyte bactericidal activity J:91980
impaired macrophage chemotaxis J:63134
impaired neutrophil phagocytosis J:91980
increased lymphocyte cell number J:63134
increased susceptibility to fungal infection J:95637
increased susceptibility to parasitic infection J:87817
Plautm1Mlg/Plautm1Mlg
(B6.Cg-Plautm1Mlg)
abnormal acute phase protein level J:68083
abnormal cytokine level J:75303
decreased inflammatory response J:68083
decreased susceptibility to induced arthritis J:75303
decreased T cell proliferation J:75303
impaired macrophage chemotaxis J:68083
Plautm1Mlg/Plautm1Mlg
(B6.129S2-Plautm1Mlg)
chronic inflammation J:164542
increased inflammatory response J:164542
liver inflammation J:164542
trachea inflammation J:164542
Plaurtm1Jld/Plaurtm1Jld
(involves: 129P2/OlaHsd * Black Swiss)
abnormal macrophage physiology J:26874
Plaurtm1Jld/Plaurtm1Jld
(B6.129P2-Plaurtm1Jld)
chronic inflammation J:164542
increased inflammatory response J:164542
liver inflammation J:164542
trachea inflammation J:164542
Plaurtm1Jld/Plaurtm1Jld
Tg(MSR1-Plau)1Ddi/0

(B6.Cg-Plaurtm1Jld Tg(MSR1-Plau)1Ddi)
heart inflammation J:113474
Plaurtm1Mlg/Plaurtm1Mlg
(involves: 129S2/SvPas * C57BL/6)
abnormal cytokine level J:75573
abnormal macrophage physiology J:31253
abnormal neutrophil physiology J:75573, J:91980
impaired neutrophil phagocytosis J:91980
increased susceptibility to bacterial infection J:75573
Plcb1em1(IMPC)Mbp/Plcb1+
(C57BL/6N-Plcb1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Plcb2tm1b(KOMP)Wtsi/Plcb2tm1b(KOMP)Wtsi
(C57BL/6N-Plcb2tm1b(KOMP)Wtsi/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Plcb2tm1Dwu/Plcb2tm1Dwu
(involves: 129)
abnormal leukocyte physiology J:41948
decreased susceptibility to bacterial infection J:41948
decreased susceptibility to infection J:41948
decreased susceptibility to viral infection J:41948
Plcb2tm1Dwu/Plcb2tm1Dwu
Plcb3tm1Dwu/Plcb3tm1Dwu

(involves: 129S1/Sv)
abnormal neutrophil physiology J:60348
increased immunoglobulin level J:60348
Plcd1tm1.1Kfu/Plcd1tm1.1Kfu
Tg(KRT14-cre)1Amc/0

(involves: C57BL/6 * C57BL/6JJcl * CBA)
decreased B cell number J:205633
enlarged inguinal lymph nodes J:205633
increased circulating interleukin-17 level J:205633
increased granulocyte number J:205633
increased interleukin-17 secretion J:205633
increased NK T cell number J:205633
increased susceptibility to type IV hypersensitivity reaction J:205633
Plcd1tm1Tta/Plcd1tm1Tta
(involves: 129P2/OlaHsd)
abnormal granulocyte differentiation J:205633
decreased B cell number J:205633
enlarged axillary lymph nodes J:205633
enlarged inguinal lymph nodes J:205633
enlarged lymph nodes J:205633
enlarged spleen J:205633
increased circulating interleukin-17 level J:205633
increased granulocyte number J:205633
increased interleukin-17 secretion J:205633
increased leukocyte cell number J:205633
Plce1em1(IMPC)Mbp/Plce1em1(IMPC)Mbp
(C57BL/6N-Plce1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Plcg1tm1Gcrp/Plcg1tm1Rwen
Tg(Cd4-cre)1Cwi/0

(either: B6.Cg-Plcg1tm1Gcrp/Plcg1tm1Rwen Tg(Cd4-cre)1Cwi or (involves: 129X1/SvJ * C57BL/6 * DBA/2))
abnormal T cell activation J:157757
decreased regulatory T cell number J:157757
decreased T cell number J:157757
dermatitis J:157757
ear inflammation J:157757
increased anti-double stranded DNA antibody level J:157757
increased CD4-positive, alpha-beta T cell number J:157757
increased T cell proliferation J:157757
skin inflammation J:157757
Plcg1tm1Gcrp/Plcg1tm1Rwen
Tg(Cd4-cre)1Cwi/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129X1/SvJ * C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:157757
decreased double-negative T cell number J:157757
increased CD8-positive, alpha-beta T cell number J:157757
increased double-positive T cell number J:157757
thymus hyperplasia J:157757
Plcg2al/Plcg2al
(involves: 129 * C57BL/6)
abnormal lymphatic vessel morphology J:143529
Plcg2Ali5/Plcg2+
(C3HeB/FeJ-Plcg2Ali5)
abnormal B cell physiology J:97930
chronic inflammation J:97930
decreased B-2 B cell number J:97930
dermatitis J:97930
osteoarthritis J:97930
Plcg2Ali5/Plcg2+
(involves: C57BL/6J * C3HeB/FeJ-Plcg2Ali5)
abnormal B cell physiology J:97930
glomerulonephritis J:97930
immune system phenotype J:97930
Plcg2Ali5/Plcg2+
Rag1tm1Mom/Rag1tm1Mom

(involves: 129S7/SvEvBrd * C3HeB/FeJ * C3HeB/FeJ-Plcg2Ali5)
chronic inflammation J:97930
dermatitis J:97930
osteoarthritis J:97930
Plcg2Ali5/Plcg2Ali5
(involves: C57BL/6J * C3HeB/FeJ-Plcg2Ali5)
abnormal B cell physiology J:97930
chronic inflammation J:97930
decreased mature B cell number J:97930
decreased transitional stage B cell number J:97930
glomerulonephritis J:97930
Plcg2Ali14/Plcg2+
(C3HeB/FeJ-Plcg2Ali14)
abnormal inflammatory response J:166106
Plcg2em1Msasn/Plcg2em1Msasn
(B6.Cg-Plcg2em1Msasn/J)
impaired macrophage phagocytosis J:308279
Plcg2m1Btlr/Plcg2m1Btlr
(C57BL/6J-Plcg2m1Btlr)
decreased IgM level J:165702
Plcg2m1Btlr/Plcg2m1Btlr
(involves: C57BL/6J)
abnormal B cell differentiation J:185495
decreased IgM level J:185495
immune system phenotype J:185495
Plcg2M2Btlr/Plcg2+
(C57BL/6J-Plcg2M2Btlr)
decreased tumor necrosis factor secretion J:218966
Plcg2M2Btlr/Plcg2M2Btlr
(C57BL/6J-Plcg2M2Btlr)
decreased tumor necrosis factor secretion J:218966
Plcg2M3Btlr/Plcg2M3Btlr
(C57BL/6J-Plcg2M3Btlr)
abnormal humoral immune response J:265101
decreased B-1a cell number J:265101
decreased IgM level J:265101
Plcg2m4Btlr/Plcg2m4Btlr
(C57BL/6J-Plcg2m4Btlr)
decreased CD8-positive, naive alpha-beta T cell number J:272862
increased effector memory CD8-positive, alpha-beta T cell number J:272862
Plcg2tm1.1Kuro/Plcg2tm1.1Kuro
(B6.Cg-Plcg2tm1.1Kuro)
decreased interferon-gamma secretion J:131621
impaired natural killer cell mediated cytotoxicity J:131621
Plcg2tm1.1Kuro/Plcg2tm1.1Kuro
(Not Specified)
abnormal B cell differentiation J:131161
abnormal NK cell physiology J:187430
increased pro-B cell number J:131161
spleen hyperplasia J:131161
Plcg2tm1Ichi/Plcg2tm1Ichi
(involves: 129 * C57BL/6)
abnormal lymphatic vessel morphology J:143529
Plcg2tm1Jni/Plcg2tm1Jni
(involves: 129P2/OlaHsd)
abnormal B cell physiology J:80614
abnormal dendritic cell chemotaxis J:157619
abnormal dendritic cell morphology J:157619
abnormal dendritic cell physiology J:157619
arrested B cell differentiation J:86373
decreased B cell proliferation J:80614
decreased follicular B cell number J:86373
decreased mature B cell number J:104166
decreased susceptibility to induced arthritis J:157619
increased B cell apoptosis J:86373
increased pro-B cell number J:104166
increased transitional stage T2 B cell number J:86373
Plcg2tm1Jni/Plcg2tm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:117023
abnormal B cell physiology J:117023
abnormal osteoclast differentiation J:114607
decreased interferon-gamma secretion J:100716
decreased osteoclast cell number J:114607
impaired natural killer cell mediated cytotoxicity J:100716
increased B cell proliferation J:117023
increased pre-B cell number J:117023
increased susceptibility to Herpesvirales infection J:100716
Plcg2tm1Jni/Plcg2tm1Jni
Tg(IghMyc)22Bri/0

(involves: 129P2/OlaHsd * C57BL * C57BL/6 * SJL)
enlarged lymph nodes J:117023
Plcg2tm1Kuro/Plcg2tm1Kuro
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal humoral immune response J:63744
decreased B cell proliferation J:63744
decreased mature B cell number J:63744
decreased pre-B cell number J:63744
immune system phenotype J:63744
increased B-1a cell number J:63744
increased immature B cell number J:63744
increased pro-B cell number J:63744
Plcl2tm1Tta/Plcl2tm1Tta
(involves: 129P2/OlaHsd)
abnormal adaptive immunity J:85960
abnormal B cell physiology J:85960
decreased B-1a cell number J:85960
decreased mature B cell number J:85960
increased anti-nuclear antigen antibody level J:85960
increased B cell proliferation J:85960
increased IgM level J:85960
Pld2tm1.1Mjow/Pld2tm1.1Mjow
(Not Specified)
abnormal neutrophil physiology J:183062
Pld3em1Nemz/Pld3em1Nemz
(C57BL/6J-Pld3em1Nemz)
immune system phenotype J:281205
increased interleukin-6 secretion J:281205
Pld3em1Nemz/Pld3em1Nemz
Pld4tm1.2Nemz/Pld4tm1.2Nemz

(B6.Cg-Pld3em1Nemz Pld4tm1.1Nemz)
abnormal circulating chemokine level J:281205
hemophagocytosis J:281205
increased circulating CXCL10 level J:281205
increased circulating interferon-gamma level J:281205
increased circulating tumor necrosis factor level J:281205
liver inflammation J:281205
Pld4em1(IMPC)Mbp/Pld4em1(IMPC)Mbp
(C57BL/6N-Pld4em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased leukocyte cell number J:211773
increased monocyte cell number J:211773
increased spleen weight J:211773
Pld4thss/Pld4thss
(BALB/cJ-Pld4thss/GrsrJ)
abnormal alpha-beta T cell morphology J:278304
abnormal immunoglobulin level J:278304
enlarged lymph nodes J:278304
enlarged spleen J:278304
increased anti-nuclear antigen antibody level J:278304
increased IgA level J:278304
increased IgE level J:278304
increased IgG2b level J:278304
increased IgG3 level J:278304
increased IgG level J:278304
increased IgM level J:278304
increased macrophage cell number J:278304
increased marginal zone B cell number J:278304
increased plasma cell number J:278304
increased plasmacytoid dendritic cell number J:278304
increased spleen germinal center number J:278304
lymph node hyperplasia J:278304
spleen hyperplasia J:278304
Pld4tm1.1Nemz/Pld4tm1.1Nemz
Tg(Itgax-cre)1-1Reiz/0

(involves: 129 * C57BL/6 * C57BL/6J * CBA)
abnormal peritoneal macrophage morphology J:281205
Pld4tm1.2Nemz/Pld4tm1.2Nemz
(B6.129(Cg)-Pld4tm1.1Nemz)
abnormal leukocyte cell number J:281205
abnormal peritoneal macrophage morphology J:281205
decreased B-1 B cell number J:281205
decreased NK T cell number J:281205
enlarged spleen J:281205
immune system phenotype J:281205
increased circulating CXCL10 level J:281205
increased circulating interferon-gamma level J:281205
increased marginal zone B cell number J:281205
increased monocyte cell number J:281205
Pld4tm1.2Nemz/Pld4tm1.2Nemz
Rag1tm1Mom/Rag1tm1Mom

(involves: 129 * 129S7/SvEvBrd * C57BL/6J * FVB/N)
abnormal peritoneal macrophage morphology J:281205
decreased NK T cell number J:281205
Pld4tm1.2Nemz/Pld4tm1.2Nemz
Tlr9M7Btlr/Tlr9M7Btlr

(involves: 129 * C57BL/6J * FVB/N)
immune system phenotype J:281205
Plectm3Gwi/Plectm3Gwi
(involves: 129P2/OlaHsd)
abnormal T cell physiology J:104701
impaired macrophage chemotaxis J:104701
Plek2tm1Pji/Plek2tm1Pji
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal granulocyte differentiation J:257910
enlarged spleen J:257910
Plek2tm1Pji/Plek2tm1Pji
Jak2tm1.1Ble/Jak2+
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca)
abnormal granulocyte differentiation J:257910
immune system phenotype J:257910
Plekha5em1(IMPC)Tcp/Plekha5em1(IMPC)Tcp
(C57BL/6NCrl-Plekha5em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
increased spleen weight J:211773
Plekha7tm1.1Janc/Plekha7tm1.1Janc
(involves: C57BL/6)
decreased susceptibility to bacterial infection J:227858
decreased susceptibility to bacterial infection induced morbidity/mortality J:227858
Plekhf1tm1.1Caox/Plekhf1tm1.1Caox
Lyz2tm1(cre)Ifo/Lyz2+

(B6.Cg-Plekhf1tm1.1Caox Lyz2tm1(cre)Ifo)
abnormal cytokine secretion J:277440
abnormal macrophage physiology J:277440
decreased circulating interferon-beta level J:277440
decreased circulating interleukin-6 level J:277440
decreased circulating tumor necrosis factor level J:277440
increased susceptibility to bacterial infection J:277440
increased susceptibility to bacterial infection induced morbidity/mortality J:277440
Plekhg2em1(IMPC)J/Plekhg2em1(IMPC)J
(C57BL/6NJ-Plekhg2em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Plekhm1tm1.2Hzhao/Plekhm1tm1.2Hzhao
(involves: 129S1/Sv * C57BL/6J)
abnormal osteoclast morphology J:236517
abnormal osteoclast physiology J:236517
Plekhm2tm1a(EUCOMM)Wtsi/Plekhm2tm1a(EUCOMM)Wtsi
(B6JTyr;B6N-Plekhm2tm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:165965
Plekhm2tm1a(EUCOMM)Wtsi/Plekhm2tm1a(EUCOMM)Wtsi
(involves: C57BL/6J * C57BL/6N)
decreased susceptibility to bacterial infection J:233985
decreased susceptibility to bacterial infection induced morbidity/mortality J:233985
increased leukocyte cell number J:233985
Plekho2em1Lzhn/Plekho2em1Lzhn
(C57BL/6-Plekho2em1Lzhn)
decreased macrophage cell number J:270531
immune system phenotype J:270531
increased macrophage apoptosis J:270531
Plet1tm1Cupe/Plet1tm1Cupe
(Not Specified)
abnormal dendritic cell migration J:271548
abnormal dendritic cell number J:271548
increased dendritic cell number J:271548
Plgtm1.1Fjc/Plgtm1.1Fjc
(involves: C57BL/6 * C57BL/6JJcl)
enlarged lymph nodes J:210802
increased circulating fibrinogen level J:210802
Plgtm1Dco/Plg+
(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6)
abnormal inflammatory response J:80114
Plgtm1Dco/Plgtm1Dco
(involves: 129S2/SvPas * C57BL/6)
abnormal acute phase protein level J:82604
Plgtm1Dco/Plgtm1Dco
(involves: 129S2/SvPas * 129X1/SvJ * C57BL/6)
abnormal inflammatory response J:80114
Plgtm1Dco/Plgtm1Dco
(involves: 129S2/SvPas)
enlarged lymph nodes J:210802
increased circulating fibrinogen level J:210802
Plgtm1Jld/Plgtm1Jld
(involves: 129P2/OlaHsd * NIH Black Swiss)
proctitis J:39419
Plgtm1Jld/Plgtm1Jld
(B6.129P2-Plgtm1Jld)
conjunctivitis J:46096
eye inflammation J:46096
Plgtm1Jld/Plgtm1Jld
(involves: 129P2/OlaHsd * Black Swiss)
colitis J:36591
Plgtm1Jld/Plgtm1Jld
(B6.129P2-Plgtm1Jld/J)
abnormal microglial cell physiology J:141739
Plgr1BALB/cJ/Plgr1BALB/cJ
(involves: BALB/cJ * C57BL/6J)
decreased susceptibility to bacterial infection J:138895
Plgr1BALB/cJ/Plgr1BALB/cJ
(B6.C-Plgr1BALB/cJ)
decreased susceptibility to bacterial infection J:138895
Plgr1BALB/cJ/Plgr1C57BL/6J
(involves: BALB/cJ * C57BL/6J)
decreased susceptibility to bacterial infection J:138895
Plgr1BALB/cJ/Plgr1C57BL/6J
(B6.C-Plgr1BALB/cJ)
decreased susceptibility to bacterial infection J:138895
Plgrkttm1Rjpr/Plgrkt+
(B6.Cg-Plgrkttm1Rjpr)
dermatitis J:282437
Plgrkttm1Rjpr/Plgrkttm1Rjpr
(B6.Cg-Plgrkttm1Rjpr)
abnormal macrophage physiology J:282437
dermatitis J:282437
impaired leukocyte migration J:282437
impaired macrophage chemotaxis J:282437
Plin2tm1.1Asg/Plin2tm1.1Asg
(B6.129S2(Cg)-Plin2tm1.1Asg)
decreased inflammatory response J:196302
Plp1jp-rsh/Plp1+
(either: STOCK Rb(1.3)1Bnr or (involves: BALB/c * DBA/2 * STOCK Rb(1.3)1Bnr))
abnormal microglial cell morphology J:604
Plp1jp-rsh/Plp1jp-rsh
(involves: 101/H * C3H)
decreased susceptibility to Picornaviridae infection J:41447
Plp1tm1c(EUCOMM)Wtsi/Y
Cnptm1(cre)Kan/Cnp+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N)
increased T cell number J:245100
microgliosis J:245100
Plp1tm1Kan/Y
(involves: 129S1/Sv * 129X1/SvJ)
abnormal microglial cell morphology J:48031
microgliosis J:245100
Plp1tm1Kan/Y
(B6.129-Plp1tm1Kan)
microgliosis J:201143
Plp1tm1Kan/Y
Cnptm1(cre)Kan/Cnp+

(involves: 129S1/Sv * 129X1/SvJ)
increased T cell number J:245100
microgliosis J:245100
Plp1tm1Kan/Y
Tspan2tm1Hbw/Tspan2tm1Hbw

(B6.Cg-Tspan2tm1Hbw Plp1tm1Kan)
brain inflammation J:201143
microgliosis J:201143
Plpp5tm1(KOMP)Mbp/Plpp5tm1(KOMP)Mbp
Prdm1tm1Nutt/Prdm1+

(involves: C57BL/6 * C57BL/6N)
immune system phenotype J:265892
Plppr5em1(IMPC)Ccpcz/Plppr5em1(IMPC)Ccpcz
(C57BL/6NCrl-Plppr5em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Plppr5em1(IMPC)H/Plppr5em1(IMPC)H
(C57BL/6NTac-Plppr5em1(IMPC)H/H)
increased neutrophil cell number J:211773
Pls1tm1Fri/Pls1tm1Fri
(B6.129-Pls1tm1Fri)
increased susceptibility to colitis induced morbidity/mortality J:216723
increased susceptibility to induced colitis J:216723
Plscr1tm1Lex/Plscr1tm1Lex
(129S/SvEvBrd-Plscr1tm1Lex)
abnormal granulocyte differentiation J:76790
abnormal myelopoiesis J:76790
abnormal neutrophil differentiation J:76790
decreased granulocyte number J:76790
decreased neutrophil cell number J:76790
Plscr1tm1Lex/Plscr1tm1Lex
Plscr3tm1Sims/Plscr3tm1Sims

(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal myelopoiesis J:92404
plt/plt
(involves: DDD/1)
abnormal immune system organ morphology J:47819
abnormal immune system physiology J:47819
abnormal leukocyte cell number J:47819
abnormal leukocyte migration J:47819, J:47460
abnormal lymph node T cell domain morphology J:47819, J:47460
abnormal peripheral lymph node morphology J:47819
abnormal spleen red pulp morphology J:47460
abnormal spleen white pulp morphology J:47460
decreased single-positive T cell number J:15290
decreased T cell number J:47819
increased memory T cell number J:47460
increased T cell number J:47819
lymph node hypoplasia J:15290, J:47460
small Peyer's patches J:47460
plt/plt
(C.DDD-plt)
abnormal T cell activation J:119345
decreased single-positive T cell number J:119345
increased length of allograft survival J:119345
plt/plt
(B6.DDD-plt)
abnormal leukocyte migration J:93960
abnormal thymus cortex morphology J:93960
immune system phenotype J:93960
small thymus medulla J:93960
plt/plt
(either: B6.DDD-plt or C.DDD-plt)
abnormal leukocyte migration J:110910
increased inflammatory response J:110910
increased susceptibility to autoimmune disorder J:110910
lacrimal gland inflammation J:110910
parotid gland inflammation J:110910
salivary gland inflammation J:110910
submandibular gland inflammation J:110910
Plvaptm1e(EUCOMM)Hmgu/Plvaptm1e(EUCOMM)Hmgu
Tg(TIE2GFP)287Sato/0

(involves: C57BL/6N * FVB/N)
small spleen J:203907
Plxna1tm1Kik/Plxna1tm1Kik
(either: B6.Cg-Plxna1tm1Kik or C.Cg-Plxna1tm1Kik)
abnormal CD4-positive, alpha-beta T cell physiology J:110786
abnormal dendritic cell physiology J:110786
Plxna1tm1Kik/Plxna1tm1Kik
(Not Specified)
abnormal dendritic cell physiology J:161856
Plxna1tm1Kik/Plxna1tm1Kik
Tg(TcraTcrb)425Cbn/?

(involves: BALB/c * C57BL/6)
decreased T cell proliferation J:161856
Plxna1tm1Tmj/Plxna1tm1Tmj
(involves: 129S/SvEv)
abnormal lymphatic vessel endothelial cell morphology J:226501
abnormal lymphatic vessel morphology J:226501
Plxna2tm1Hfu/Plxna2tm1Hfu
(involves: C57BL/6NCrlj * CBA/JNCrlj)
abnormal lymphatic vessel morphology J:226501
Plxna4em1(IMPC)Mbp/Plxna4em1(IMPC)Mbp
(C57BL/6NCrl-Plxna4em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Plxnc1em1(IMPC)Mbp/Plxnc1em1(IMPC)Mbp
(C57BL/6N-Plxnc1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Plxnd1b2b1863Clo/Plxnd1b2b1863Clo
(C57BL/6J-Plxnd1b2b1863Clo)
thymus hypoplasia J:175213
Plxnd1b2b3150Clo/Plxnd1b2b3150Clo
(C57BL/6J-Plxnd1b2b3150Clo)
thymus hypoplasia J:175213
PlyidHIGA/Nsc/PlyidHIGA/Nsc
(involves: BALB/cA * HIGA/Nsc)
abnormal humoral immune response J:91769
increased IgA level J:91769
Pmaip1tm1Ast/Pmaip1tm1Ast
(C57BL/6-Pmaip1tm1Ast)
abnormal NK cell morphology J:123409
Pmaip1tm1Ast/Pmaip1tm1Ast
(involves: C57BL/6)
immune system phenotype J:132819
Pmepa1em1Akt/Pmepa1em1Akt
(C57BL/6N-Pmepa1em1Akt)
abnormal osteoclast differentiation J:329578
abnormal osteoclast physiology J:329578
decreased osteoclast cell number J:329578
Pmltm1(PML/RARA)Ley/Pml+
Tg(CAG-cre/Esr1*)5Amc/0

(involves: BALB/cJ * C57BL/6 * CBA)
enlarged spleen J:172024
Pmltm1.1Ews/Pmltm1.1Ews
Tg(PML-RARA)556Kog/0

(FVB.Cg-Pmltm1.1Ews Tg(PML-RARA)556Kog)
enlarged spleen J:262172
increased leukocyte cell number J:262172
Pmltm1Ppp/Pml+
Trp53tm3.1Glo/Trp53+

(B6.129S7(Cg)-Pmltm1Ppp Trp53tm3.1Glo)
hepatosplenomegaly J:317504
Pmltm1Ppp/Pmltm1Ppp
(involves: 129S7/SvEvBrd)
abnormal immune system cell morphology J:46381
abnormal myelopoiesis J:46381
decreased granulocyte number J:46381
decreased leukocyte cell number J:46381
increased susceptibility to bacterial infection J:46381
Pmltm1Ppp/Pmltm1Ppp
Trp53tm3.1Glo/Trp53+

(B6.129S7(Cg)-Pmltm1Ppp Trp53tm3.1Glo)
hepatosplenomegaly J:317504
Pmm2tm1b(EUCOMM)Hmgu/Pmm2+
(C57BL/6N-Pmm2tm1b(EUCOMM)Hmgu/Tcp)
enlarged lymph nodes J:211773
Pms2tm1.1Wed/Pms2tm1.1Wed
(involves: 129S6/SvEvTac * C57BL/6NCr)
abnormal class switch recombination J:162378
Pms2tm1Lisk/Pms2tm1Lisk
(involves: 129S2/SvPas)
abnormal class switch recombination J:162378
Pnliprp2tm1Gru/Pnliprp2tm1Gru
(involves: 129S2/SvPas * BALB/c)
decreased cytotoxic T cell cytolysis J:51627
Pno1tm1Jwu/Pno1+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:191966
Pnpbata/Pnpbata
(C57BL/6JSfdAnu-Pnpbata)
decreased B cell proliferation J:104190
decreased marginal zone B cell number J:104190
increased T follicular helper cell number J:104190
Pnpe/Pnpe
(C57BL/6J-Pnpe)
abnormal leukocyte physiology J:39328
thymus hypoplasia J:39328
Pnpf/Pnpf
(involves: C3H/HeHa * C57BL/6J)
increased double-negative T cell number J:522
Pnpf/Pnpf
(C57BL/6J-Pnpf)
abnormal leukocyte cell number J:39328
abnormal leukocyte physiology J:39328
decreased CD8-positive, alpha-beta T cell number J:39328
decreased double-positive T cell number J:39328
thymus hypoplasia J:39328
Pnpg/Pnpg
(involves: C57BL/6 * DBA/2J)
abnormal leukocyte cell number J:39328
abnormal leukocyte physiology J:39328
decreased CD8-positive, alpha-beta T cell number J:39328
decreased double-positive T cell number J:39328
increased double-negative T cell number J:39328
thymus hypoplasia J:39328
PnpM1Btlr/PnpM1Btlr
(C57BL/6J-PnpM1Btlr)
impaired humoral immune response J:265147
increased IgM level J:265147
Pnpm2Btlr/Pnpm2Btlr
(C57BL/6J-Pnpm2Btlr)
decreased B-1a cell number J:265150
decreased B-2 B cell number J:265150
decreased CD4-positive, alpha-beta T cell number J:265150
decreased CD8-positive, naive alpha-beta T cell number J:265150
decreased T cell number J:265150
increased B-1b cell number J:265150
increased CD8-positive, alpha-beta memory T cell number J:265150
increased central memory CD4-positive, alpha-beta T cell number J:265150
increased central memory CD8 positive, alpha-beta T cell number J:265150
increased effector memory CD4-positive, alpha-beta T cell number J:265150
increased effector memory CD8-positive, alpha-beta T cell number J:265150
Pnptm1Cmr/Pnptm1Cmr
(involves: 129)
abnormal myelopoiesis J:62870
decreased CD4-positive, alpha-beta T cell number J:62870
decreased CD8-positive, alpha-beta T cell number J:62870
decreased cytotoxic T cell cytolysis J:62870
decreased double-positive T cell number J:62870
decreased single-positive T cell number J:62870
increased double-negative T cell number J:62870
increased pre-B cell number J:62870
increased thymocyte apoptosis J:62870
Pnpla5em1(IMPC)Mbp/Pnpla5em1(IMPC)Mbp
(C57BL/6N-Pnpla5em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Podxl2tm1.1(KOMP)Vlcg/Podxl2tm1.1(KOMP)Vlcg
(C57BL/6N-Podxl2tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Pofut1tm2Pst/Pofut1tm1Pst
Shhtm2(cre/ERT2)Cjt/Shh+

(involves: 129/Sv * 129S6/SvEvTac * C57BL/6J * SJL)
lung inflammation J:150051
Polbtm1.1Jbsw/Polb+
(involves: 129/Sv * C57BL/6)
dermatitis J:206872
enlarged cervical lymph nodes J:206872
glomerulonephritis J:206872
increased anti-nuclear antigen antibody level J:206872
increased IgG level J:206872
lymph node inflammation J:206872
salivary gland inflammation J:206872
Polbtm1.1Jbsw/Polbtm1.1Jbsw
(involves: 129/Sv * C57BL/6)
abnormal immunoglobulin heavy chain V(D)J recombination J:206872
abnormal somatic hypermutation frequency J:206872
abnormal spleen germinal center morphology J:206872
dermatitis J:206872
enlarged cervical lymph nodes J:206872
glomerulonephritis J:206872
increased anti-nuclear antigen antibody level J:206872
increased germinal center B cell number J:206872
increased IgG level J:206872
increased spleen germinal center number J:206872
increased splenocyte apoptosis J:183837, J:206872
increased susceptibility to systemic lupus erythematosus J:206872
increased T-helper 2 cell number J:206872
lymph node inflammation J:206872
salivary gland inflammation J:206872
Polbtm1a(KOMP)Wtsi/Polbtm1a(KOMP)Wtsi
(C57BL/6N-Polbtm1a(KOMP)Wtsi/Wtsi)
abnormal lymphatic vessel topology J:239583
Polbtm1Rsky/Polbtm1Rsky
Tg(Lck-cre)I57Jxm/0

(involves: 129P2/OlaHsd * ICR)
immune system phenotype J:67942
Pold1tm1.1Uchi/Pold1tm1.1Uchi
(C57BL/6-Pold1tm1.1Uchi)
enlarged thymus J:144992
Pold1tm1Uchi/Pold1tm1.1Uchi
(C57BL/6-Pold1tm1Uchi/Pold1tm1.1Uchi)
enlarged thymus J:144992
Pold4em1(IMPC)J/Pold4em1(IMPC)J
(C57BL/6NJ-Pold4em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Pole2em1(IMPC)Mbp/Pole2+
(C57BL/6NCrl-Pole2em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Pole3em1Tbo/Pole3em1Tbo
(FVB-Pole3em1Tbo)
decreased B cell number J:298827
decreased lymphocyte cell number J:298827
decreased splenocyte number J:298827
decreased thymocyte number J:298827
Pole3em2Tbo/Pole3em2Tbo
(FVB-Pole3em2Tbo)
decreased B cell number J:298827
decreased lymphocyte cell number J:298827
decreased splenocyte number J:298827
decreased thymocyte number J:298827
Pole3em3Tbo/Pole3em3Tbo
(FVB-Pole3em3Tbo)
abnormal thymus apoptosis J:298827
decreased B cell number J:298827
decreased DN4 thymocyte number J:298827
decreased double-positive T cell number J:298827
decreased gamma-delta T cell number J:298827
decreased immature B cell number J:298827
decreased lymphocyte cell number J:298827
decreased pre-B cell number J:298827
decreased splenocyte number J:298827
decreased thymocyte number J:298827
increased DN3 thymocyte number J:298827
increased thymocyte apoptosis J:298827
small spleen J:298827
small thymus J:298827
Pole3em4Tbo/Pole3em4Tbo
(FVB-Pole3em4Tbo)
abnormal thymus apoptosis J:298827
decreased B cell number J:298827
decreased DN4 thymocyte number J:298827
decreased immature B cell number J:298827
decreased lymphocyte cell number J:298827
decreased pre-B cell number J:298827
decreased splenocyte number J:298827
decreased thymocyte number J:298827
increased DN3 thymocyte number J:298827
increased thymocyte apoptosis J:298827
Pole3tm1(KOMP)Vlcg/Pole3tm1(KOMP)Vlcg
(involves: C57BL/6NTac * FVB)
decreased DN4 thymocyte number J:298827
increased DN3 thymocyte number J:298827
Pole4tm1(KOMP)Vlcg/Pole4tm1(KOMP)Vlcg
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac * FVB/N)
abnormal B cell differentiation J:261973
abnormal mesenteric lymph node morphology J:261973
abnormal spleen B cell follicle morphology J:261973
abnormal T cell differentiation J:261973
abnormal thymus morphology J:261973
absent thymus cortex J:261973
arrested B cell differentiation J:261973
athymia J:261973
decreased B cell number J:261973
decreased leukocyte cell number J:261973
decreased lymphocyte cell number J:261973
decreased single-positive T cell number J:261973
decreased spleen weight J:261973
increased double-negative T cell number J:261973
increased granulocyte number J:261973
increased monocyte cell number J:261973
small spleen J:261973
Pole4tm1(KOMP)Vlcg/Pole4tm1(KOMP)Vlcg
Trp53tm1Brd/Trp53+

(involves: C57BL/6J * C57BL/6NTac)
decreased leukocyte cell number J:261973
decreased lymphocyte cell number J:261973
increased granulocyte number J:261973
increased monocyte cell number J:261973
Pole4tm1(KOMP)Vlcg/Pole4tm1(KOMP)Vlcg
Trp53tm1Brd/Trp53tm1Brd

(involves: C57BL/6J * C57BL/6NTac)
immune system phenotype J:261973
Poletm1.1Bdp/Poletm1.1Bdp
(B6.129-Poletm1.1Bdp)
enlarged spleen J:153684
Polgtm1Prol/Polgtm1Prol
(involves: 129S7/SvEvBrd * C57BL/6J * ICR)
abnormal thymus involution J:99764
Polgtm1Prol/Polgtm1Prol
(B6J.129S7-Polgtm1Prol)
abnormal lymphopoiesis J:154187
decreased double-positive T cell number J:154187
decreased immature B cell number J:154187
decreased lymphocyte cell number J:154187
decreased mature B cell number J:154187
decreased pre-B cell number J:154187
decreased pro-B cell number J:154187
decreased thymocyte number J:154187
Polhtm1Crey/Polhtm1Crey
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:98037
Polhtm1Crey/Polhtm1Crey
Polid/Polid

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:98037
Polhtm1Fmh/Polhtm1Fmh
(involves: C57BL/6)
abnormal B cell physiology J:99721
Polid/Polid
Polktm1Hohm/Polktm1Hohm

(involves: 129X1/SvJ * C57BL/6 * CBA)
immune system phenotype J:105111
Polktm1.1Rsky/Polktm1.1Rsky
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
immune system phenotype J:80212
Polktm1Hohm/Polktm1Hohm
(involves: 129X1/SvJ * C57BL/6 * CBA)
immune system phenotype J:105111
Polktm1Hohm/Polktm1Hohm
(involves: C57BL/6 * CBA)
immune system phenotype J:83202
Polltm1Crey/Polltm1Crey
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:75927
Polltm1Crey/Polltm1Crey
(involves: 129P2/OlaHsd)
abnormal immunoglobulin heavy chain V(D)J recombination J:113406
immune system phenotype J:113406
Polltm1Crey/Polltm1Crey
Polmtm1Crey/Polmtm1Crey

(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:113406
abnormal immunoglobulin heavy chain V(D)J recombination J:113406
abnormal immunoglobulin light chain V-J recombination J:113406
decreased B cell number J:113406
Polmm1Btlr/Polmm1Btlr
(C57BL/6J-Polmm1Btlr)
decreased B cell number J:272866
Polmm2Btlr/Polmm2Btlr
(C57BL/6J-Polmm2Btlr)
abnormal lymphocyte morphology J:272867
decreased B cell number J:272867
Polmtm1Abnd/Polmtm1Abnd
(involves: 129/Sv * BALB/c)
abnormal B cell number J:97782
Polmtm1Crey/Polmtm1Crey
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell proliferation J:85190
abnormal Peyer's patch morphology J:85190
decreased B cell number J:75927, J:85190
immune system phenotype J:75927
lymphoid hypoplasia J:85190
Polmtm1Crey/Polmtm1Crey
(involves: 129P2/OlaHsd)
abnormal immunoglobulin light chain V-J recombination J:113406
Polqem1(IMPC)Mbp/Polqem1(IMPC)Mbp
(C57BL/6N-Polqem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Polqtm1Jcs/Polqtm1Jcs
(involves: 129S4/SvJae * C57BL/6J)
abnormal somatic hypermutation frequency J:103365
Polqtm1Jow/Polqtm1Jow
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N)
abnormal B cell physiology J:101409
abnormal somatic hypermutation frequency J:101409
decreased IgG1 level J:101409
decreased IgG level J:101409
decreased IgM level J:101409
decreased immunoglobulin level J:101409
Polqtm2Jow/Polqtm2Jow
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal somatic hypermutation frequency J:115989
Polr1bem1(IMPC)Tcp/Polr1b+
(C57BL/6NCrl-Polr1bem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged thymus J:211773
Polr2atm1(cre/ERT2)Bbd/Polr2a+
Rnf2tm1Mvi/Rnf2tm1Mvi

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10 * SJL)
decreased B cell number J:130397
Polr3aem2(IMPC)Tcp/Polr3a+
(C57BL/6NCrl-Polr3aem2(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Polrmtem1(IMPC)Mbp/Polrmt+
(C57BL/6N-Polrmtem1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Pomcem1(IMPC)Rbrc/Pomc+
(C57BL/6NJcl-Pomcem1(IMPC)Rbrc/Rbrc)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Pomctm1Low/Pomctm1Low
(involves: 129S2/SvPas * C57BL/6)
increased circulating interleukin-6 level J:102955
increased interleukin-6 secretion J:102955
increased splenocyte proliferation J:102955
increased tumor necrosis factor secretion J:102955
Pomkem1(IMPC)Hmgu/Pomk+
(C57BL/6NCrl-Pomkem1(IMPC)Hmgu/Ieg)
increased spleen weight J:211773
Pomt1Gt(OST194127)Lex/Pomt1+
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased IgG level J:103485
increased neutrophil cell number J:103485
Pon2Gt(XE661)Byg/Pon2Gt(XE661)Byg
(B6.129P2-Pon2Gt(XE661)Byg)
abnormal macrophage chemotaxis J:116935
abnormal macrophage physiology J:116935
increased susceptibility to bacterial infection J:116935
Pon2tm1b(EUCOMM)Hmgu/Pon2tm1b(EUCOMM)Hmgu
(C57BL/6N-Pon2tm1b(EUCOMM)Hmgu/H)
decreased neutrophil cell number J:211773
Pon3tm1Dmsh/Pon3tm1Dmsh
(B6J.129X1-Pon3tm1Dmsh)
liver inflammation J:234615
Postntm1Sjc/Postntm1Sjc
(involves: C57BL/6)
periodontium inflammation J:103753
Postntm1Sjc/Postntm1Sjc
(B6.Cg-Postntm1Sjc)
increased osteoclast cell number J:200192
Pot1btm1.1Schg/Pot1btm1.1Schg
Terctm1Rdp/Terc+

(involves: 129/Sv * 129S6/SvEvTac * C57BL/6 * SJL)
abnormal granulocyte morphology J:144553
decreased granulocyte number J:144553
decreased leukocyte cell number J:144553
Pot1btm1.1Schg/Pot1btm1.1Schg
Terctm1Rdp/Terctm1Rdp

(involves: 129/Sv * 129S6/SvEvTac * C57BL/6 * SJL)
abnormal granulocyte morphology J:144553
Pou1f1dw/Pou1f1dw
(DW/J Pou1f1dw)
decreased B cell number J:110683
Pou2af1tm1b(KOMP)Wtsi/Pou2af1tm1b(KOMP)Wtsi
(C57BL/6N-Pou2af1tm1b(KOMP)Wtsi/Ucd)
decreased lymphocyte cell number J:211773
decreased spleen weight J:211773
increased neutrophil cell number J:211773
Pou2af1tm1Pjln/Pou2af1tm1Pjln
(C57BL/6-Pou2af1tm1Pjln)
absent spleen germinal center J:37085
decreased B cell number J:37085
decreased IgA level J:37085
decreased IgG1 level J:37085
decreased IgG2a level J:37085
decreased IgG2b level J:37085
decreased IgG3 level J:37085
spleen hypoplasia J:37085
Pou2af1tm1Pjln/Pou2af1tm1Pjln
(involves: C57BL/6)
abnormal B cell differentiation J:67362
abnormal T-helper 1 physiology J:123039
abnormal T-helper 2 physiology J:123039
decreased B cell number J:123039, J:67362
decreased immature B cell number J:67362
decreased interferon-gamma secretion J:123039
decreased interleukin-2 secretion J:123039
decreased mature B cell number J:67362
decreased T cell number J:123039
increased B cell apoptosis J:67362
increased interleukin-4 secretion J:123039
increased interleukin-13 secretion J:123039
increased susceptibility to parasitic infection J:123039
Pou2af1tm1Pjln/Pou2af1tm1Pjln
Tg(tetO-Pou2af1)1Pjln/0
Tg(tTA)1Pjln/0

(involves: C57BL/6)
decreased B cell number J:67362
decreased immunoglobulin level J:67362
decreased mature B cell number J:67362
immune system phenotype J:67362
Pou2af1tm1Pmt/Pou2af1tm1Pmt
(involves: 129P2/OlaHsd * C57BL/6)
decreased immunoglobulin level J:125114
Pou2af1tm1Pmt/Pou2af1tm1Pmt
Ikzf3tm1Kge/Ikzf3tm1Kge

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
absent spleen germinal center J:81805
arrested B cell differentiation J:81805
decreased IgA level J:81805
decreased IgD level J:81805
decreased IgE level J:81805
decreased IgG level J:81805
decreased IgM level J:81805
decreased immunoglobulin level J:81805
Pou2af1tm1Rgr/Pou2af1tm1Rgr
(either: (involves: 129P2/OlaHsd) or (involves: 129S1/Sv))
abnormal B cell differentiation J:114816, J:35785
abnormal Peyer's patch germinal center morphology J:35785
abnormal pre-B cell morphology J:114816
absent lymph node germinal center J:35785
absent spleen germinal center J:35785
arrested B cell differentiation J:114816
decreased B cell number J:114816
decreased B cell proliferation J:35785
decreased IgA level J:35785
decreased IgE level J:35785
decreased IgG1 level J:35785
decreased IgG2a level J:35785
decreased IgG2b level J:35785
decreased IgG3 level J:35785
decreased IgG level J:35785
decreased immunoglobulin level J:35785
increased B cell proliferation J:114816
increased IgM level J:35785
Pou2af3tm1b(NCOM)Mfgc/Pou2af3tm1b(NCOM)Mfgc
(C57BL/6N-Pou2af3tm1b(NCOM)Mfgc/Tcp)
decreased lymphocyte cell number J:211773
increased leukocyte cell number J:211773
increased neutrophil cell number J:211773
Pou2f2tm1Bal/Pou2f2+
(involves: 129S2/SvPas)
decreased IgG1 level J:4555
decreased IgM level J:4555
decreased mature B cell number J:4555
Pou2f2tm1Bal/Pou2f2tm1Bal
(involves: 129S2/SvPas * C57BL/6)
arrested B cell differentiation J:88240
decreased B cell number J:88240
decreased immunoglobulin level J:88240
Pou2f2tm1Bal/Pou2f2tm1Bal
(involves: 129S2/SvPas)
decreased IgG1 level J:4555
decreased IgM level J:4555
decreased mature B cell number J:4555
Pou2f2tm1Lmc/Pou2f2tm1Lmc
(involves: C57BL/6)
arrested B cell differentiation J:88240
decreased B cell number J:88240
decreased B-1 B cell number J:88240
decreased immunoglobulin level J:88240
Pparatm1Gonz/Pparatm1Gonz
(involves: 129S4/SvJae)
heart inflammation J:63801
Ppardtm1Dsvg/Ppardtm1Dsvg
(involves: 129S2/SvPas * C57BL/6)
increased osteoclast cell number J:219677
Ppardtm1Jps/Ppardtm1Jps
(involves: 129/Sv * C57BL/6N)
skin inflammation J:63040
Ppargtm1.1Gonz/Ppargtm1.1Gonz
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6)
abnormal macrophage activation involved in immune response J:168799
abnormal peritoneal macrophage morphology J:168799
glomerulonephritis J:168799
impaired macrophage phagocytosis J:168799
increased anti-double stranded DNA antibody level J:168799
increased anti-nuclear antigen antibody level J:168799
increased anti-single stranded DNA antibody level J:168799
increased autoantibody level J:168799
increased IgG level J:168799
increased IgM level J:168799
Ppargtm1.1Gonz/Ppargtm1.1Gonz
Tg(Mx1-cre)1Cgn/?

(involves: 129X1/SvJ * C57BL/6 * CBA * FVB/N)
abnormal macrophage physiology J:75777
Ppargtm1Tka/Pparg+
(involves: C57BL/6 * CBA)
abnormal bone marrow development J:89250
leukostasis J:116269
Ppargtm1Tka/Pparg+
(involves: C57BL/6 * CBA * ICR)
abnormal B cell physiology J:58222
abnormal humoral immune response J:58222
immune system phenotype J:58222
increased B cell proliferation J:58222
increased IgG level J:58222
increased IgM level J:58222
increased interferon-gamma secretion J:58222
increased interleukin-2 secretion J:58222
increased susceptibility to induced arthritis J:58222
Ppargtm1Wwah/Pparg+
(Not Specified)
immune system phenotype J:71272
Ppargtm2Rev/Ppargtm2Rev
Tg(Cd4-cre)1Cwi/?

(involves: 129S4/SvJae * C57BL/6 * DBA/2)
abnormal T-helper 17 cell differentiation J:153358
increased susceptibility to experimental autoimmune encephalomyelitis J:153358
Ppargtm2Rev/Ppargtm2Rev
Tg(Krt1-15-cre/PGR*)22Cot/?

(involves: 129S4/SvJae * C57BL/6 * SJL)
skin inflammation J:150977
Ppargtm2Rev/Ppargtm2Rev
Tg(Tek-cre)1Ywa/?

(involves: 129S4/SvJae * C57BL/6 * SJL)
abnormal osteoclast differentiation J:160910
abnormal osteoclast morphology J:130475
abnormal spleen morphology J:130475
abnormal splenocyte morphology J:130475
decreased osteoclast cell number J:130475
enlarged spleen J:130475
increased splenocyte number J:130475
skin inflammation J:123403
Ppargtm2Rev/Ppargtm2Rev
Tg(Tek-cre)12Flv/?

(B6.Cg-Ppargtm2Rev Tg(Tek-cre)12Flv)
enlarged spleen J:154216
Ppargc1atm1Aztc/Ppargc1a+
(C57BL/6-Ppargc1atm1Aztc)
increased thymus weight J:82809
Ppargc1atm1Brsp/Ppargc1a+
(involves: 129 * FVB/N)
immune system phenotype J:127403
Ppargc1atm1Brsp/Ppargc1a+
(involves: 129S4/SvJae * C57BL/6)
increased inflammatory response J:264271
Ppargc1atm1Brsp/Ppargc1atm1Brsp
(involves: 129 * FVB/N)
increased interleukin-6 secretion J:127403
Ppargc1atm1Brsp/Ppargc1atm2Brsp
Tg(Myog-cre)1Eno/0

(involves: 129 * C57BL/6 * FVB/N)
increased circulating interleukin-6 level J:127403
Ppargc1atm2Brsp/Ppargc1a+
Tg(Myog-cre)1Eno/0

(involves: 129 * C57BL/6)
increased circulating interleukin-6 level J:127403
Ppargc1btm1.2Rev/Ppargc1btm1.2Rev
Tg(Tek-cre)1Ywa/0

(involves: 129/Sv * C57BL/6 * C57BL/6J * SJL)
abnormal osteoclast differentiation J:160910
Ppbptm1(KOMP)Vlcg/Ppbptm1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal leukocyte migration J:198197
abnormal leukocyte physiology J:198197
immune system phenotype J:198197
Ppbptm1.1(KOMP)Vlcg/Ppbptm1.1(KOMP)Vlcg
(C57BL/6N-Ppbptm1.1(KOMP)Vlcg/Ucd)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Ppfibp2em1(IMPC)Tcp/Ppfibp2em1(IMPC)Tcp
(C57BL/6NCrl-Ppfibp2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Ppiaem1(IMPC)Mbp/Ppiaem1(IMPC)Mbp
(C57BL/6NCrl-Ppiaem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Ppiatm1Lubn/Ppiatm1Lubn
(129S6.129P2-Ppiatm1Lubn)
abnormal CD4-positive, alpha-beta T cell physiology J:93591
blepharitis J:93591
heart inflammation J:93591
increased circulating interleukin-4 level J:93591
increased IgE level J:93591
increased IgG1 level J:93591
increased immunoglobulin level J:93591
increased inflammatory response J:93591
increased interleukin-2 secretion J:93591
increased interleukin-4 secretion J:93591
increased susceptibility to type I hypersensitivity reaction J:93591
increased T cell number J:93591
liver inflammation J:93591
pancreas inflammation J:93591
spleen hyperplasia J:93591
Ppicem1Igc/Ppicem1Igc
(C57BL/6-Ppicem1Igc)
decreased NK cell number J:321155
increased transitional stage T1 B cell number J:321155
increased transitional stage T2 B cell number J:321155
Ppil1em1(IMPC)Mbp/Ppil1+
(C57BL/6N-Ppil1em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Ppltm1b(KOMP)Wtsi/Ppltm1b(KOMP)Wtsi
(C57BL/6N-Ppltm1b(KOMP)Wtsi/Tcp)
enlarged lymph nodes J:211773
Ppm1atm1.2Lavi/Ppm1atm1.2Lavi
(B.129(Cg)-Ppm1atm1.2Lavi)
increased acute inflammation J:216372
Ppm1dtm1Lad/Ppm1dtm1Lad
(involves: 129S7/SvEvBrd * C57BL/6)
chronic inflammation J:74284
decreased B cell proliferation J:74284
decreased CD8-positive, alpha-beta T cell number J:74284
decreased T cell proliferation J:74284
enlarged spleen J:74284
increased CD4-positive, alpha-beta T cell number J:74284
increased susceptibility to Orthomyxoviridae infection J:74284
lymphoid hyperplasia J:74284
myeloid hyperplasia J:74284
small thymus J:74284
spleen hyperplasia J:74284
Ppm1mtm2b(EUCOMM)Hmgu/Ppm1mtm2b(EUCOMM)Hmgu
(C57BL/6N-Ppm1mtm2b(EUCOMM)Hmgu/Bay)
decreased large unstained cell number J:211773
Ppm1nem1(IMPC)Mbp/Ppm1nem1(IMPC)Mbp
(C57BL/6N-Ppm1nem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Ppp1r8tm1.1Itl/Ppp1r8tm1Ave
Tg(Alb1-cre)7Gsc/0

(involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NTac * FVB/N)
liver inflammation J:238108
Ppp1r12atm1Mzhu/Ppp1r12atm1Mzhu
Tg(Acta2-cre)#Xya/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
small intestinal inflammation J:207752
Ppp1r13btm1Suda/Ppp1r13btm1Suda
(involves: 129S1/Sv * 129X1/SvJ * ICR)
abnormal lymph circulation J:135686
abnormal lymphatic vessel morphology J:135686
Ppp1r13btm1Suda/Ppp1r13btm1Suda
Trp53tm1Sia/Trp53tm1Sia

(involves: various)
abnormal lymphatic vessel morphology J:135686
Ppp1r13lwa3-J/Ppp1r13lwa3-J
(BALB/cJ-Ppp1r13lwa3-J/J)
heart inflammation J:264272
Ppp1r14ctm1Uhl/Ppp1r14ctm1Uhl
(B6;129S6-Ppp1r14ctm1Uhl/J)
increased susceptibility to Coronaviridae infection J:288523
Ppp1r15atm1.1Ajf/Ppp1r15atm1.1Ajf
(involves: 129 * C57BL/6)
abnormal splenic cell ratio J:106905
increased spleen weight J:106905
Ppp1r17em1(IMPC)H/Ppp1r17em1(IMPC)H
(C57BL/6NTac-Ppp1r17em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Ppp1r18em1Mgin/Ppp1r18em1Mgin
(B6J.B6N-Ppp1r18em1Mgin)
abnormal T cell physiology J:331428
decreased B cell number J:331428
decreased T cell number J:331428
immune system phenotype J:331428
impaired leukocyte migration J:331428
increased leukocyte cell number J:331428
increased neutrophil cell number J:331428
small spleen J:331428
spleen hypoplasia J:331428
Ppp1r18em2Mgin/Ppp1r18em2Mgin
(B6J.B6NHsd-Ppp1r18em2Mgin)
immune system phenotype J:331428
Ppp1r18em3Mgin/Ppp1r18em3Mgin
(B6J.B6N-Ppp1r18em3Mgin)
abnormal T cell physiology J:331428
decreased B cell number J:331428
decreased T cell number J:331428
immune system phenotype J:331428
impaired leukocyte migration J:331428
increased leukocyte cell number J:331428
increased neutrophil cell number J:331428
small spleen J:331428
spleen hypoplasia J:331428
Ppp2r2btm1b(KOMP)Wtsi/Ppp2r2btm1b(KOMP)Wtsi
(C57BL/6N-Ppp2r2btm1b(KOMP)Wtsi/Tcp)
increased leukocyte cell number J:211773
increased monocyte cell number J:211773
Ppp2r2dem1(IMPC)Mbp/Ppp2r2dem1(IMPC)Mbp
(C57BL/6N-Ppp2r2dem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Ppp2r2dem1Gct/Ppp2r2dem1Gct
Tg(Lck-icre)3779Nik/0

(involves: C57BL/6 * DBA/2)
abnormal regulatory T cell physiology J:308373
increased interleukin-2 secretion J:308373
Ppp2r3ctm1Imku/Ppp2r3ctm1Imku
Tg(CD19-cre/ERT2)1Cgn/?

(involves: C57BL/6)
abnormal B cell activation J:100706
abnormal humoral immune response J:100706
decreased B cell number J:100706
decreased B cell proliferation J:100706
decreased B-1a cell number J:100706
decreased follicular B cell number J:100706
decreased immature B cell number J:100706
decreased mature B cell number J:100706
decreased pre-B cell number J:100706
decreased spleen germinal center size J:100706
decreased transitional stage B cell number J:100706
increased pro-B cell number J:100706
increased T cell number J:100706
increased transitional stage B cell number J:100706
small spleen J:100706
Ppp2r5aem1(IMPC)Mbp/Ppp2r5aem1(IMPC)Mbp
(C57BL/6N-Ppp2r5aem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Ppp2r5aGt(IST13127C10)Tigm/Ppp2r5aGt(IST13127C10)Tigm
(C57BL/6N-Ppp2r5aGt(IST13127C10)Tigm)
enlarged mesenteric lymph nodes J:254808
enlarged spleen J:254808
Ppp2r5cem1(IMPC)Mbp/Ppp2r5cem1(IMPC)Mbp
(C57BL/6N-Ppp2r5cem1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Ppp3catm1Jse/Ppp3catm1Jse
(either: (involves: 129S4/SvJae * Black Swiss) or (involves: 129S4/SvJae * C57BL/6))
decreased interferon-gamma secretion J:71750
decreased interleukin-2 secretion J:71750
decreased interleukin-4 secretion J:71750
decreased T cell proliferation J:71750
Ppp3cbM1Btlr/Ppp3cb+
(C57BL/6J-Ppp3cbM1Btlr)
abnormal CD4-positive, alpha-beta T cell physiology J:236670
abnormal CD8-positive, alpha-beta T cell physiology J:236670
abnormal NK cell physiology J:236670
increased CD8-positive, alpha-beta memory T cell proliferation J:236670
Ppp3cbM1Btlr/Ppp3cbM1Btlr
(C57BL/6J-Ppp3cbM1Btlr)
abnormal CD4-positive, alpha-beta T cell physiology J:236670
abnormal CD8-positive, alpha-beta T cell physiology J:236670
abnormal NK cell physiology J:236670
increased CD8-positive, alpha-beta memory T cell proliferation J:236670
Ppp3cbm2Btlr/Ppp3cb+
(C57BL/6J-Ppp3cbm2Btlr)
abnormal CD4-positive, alpha-beta T cell physiology J:236671
abnormal CD8-positive, alpha-beta T cell physiology J:236671
increased CD8-positive, alpha-beta memory T cell proliferation J:236671
Ppp3cbm2Btlr/Ppp3cbm2Btlr
(C57BL/6J-Ppp3cbm2Btlr)
abnormal CD4-positive, alpha-beta T cell physiology J:236671
abnormal CD8-positive, alpha-beta T cell physiology J:236671
abnormal NK cell physiology J:236671
decreased response to antigen J:236671
increased CD8-positive, alpha-beta memory T cell proliferation J:236671
Ppp3cbM3Btlr/Ppp3cb+
(C57BL/6J-Ppp3cbM3Btlr)
decreased CD8-positive, alpha-beta memory T cell number J:254889
increased central memory CD4-positive, alpha-beta T cell number J:254889
Ppp3cbM3Btlr/Ppp3cbM3Btlr
(C57BL/6J-Ppp3cbM3Btlr)
decreased CD8-positive, alpha-beta memory T cell number J:254889
decreased CD8-positive, naive alpha-beta T cell number J:254889
increased central memory CD4-positive, alpha-beta T cell number J:254889
increased central memory CD8 positive, alpha-beta T cell number J:254889
Ppp3cbM4Btlr/Ppp3cb+
(C57BL/6J-Ppp3cbM4Btlr)
decreased CD8-positive, alpha-beta memory T cell number J:254905
increased central memory CD8 positive, alpha-beta T cell number J:254905
Ppp3cbM4Btlr/Ppp3cbM4Btlr
(C57BL/6J-Ppp3cbM4Btlr)
decreased CD8-positive, alpha-beta memory T cell number J:254905
increased central memory CD8 positive, alpha-beta T cell number J:254905
Ppp3cbm5Btlr/Ppp3cbm5Btlr
(C57BL/6J-Ppp3cbm5Btlr)
abnormal T cell morphology J:272839
decreased CD8-positive, alpha-beta T cell number J:272839
Ppp3cbM6Btlr/Ppp3cbM6Btlr
(C57BL/6J-Ppp3cbM6Btlr)
abnormal lymphocyte morphology J:272840
decreased alpha-beta T cell number J:272840
decreased CD4-positive, alpha-beta T cell number J:272840
decreased CD8-positive, alpha-beta T cell number J:272840
Ppp3cbtm1Jmk/Ppp3cbtm1Jmk
(involves: 129S6/SvEvTac * C57BL/6)
abnormal T cell differentiation J:77729
decreased single-positive T cell number J:77729
decreased T cell number J:77729
decreased T cell proliferation J:77729
decreased thymus weight J:75775
thymus hypoplasia J:77729
Ppp3cbtm1Jmk/Ppp3cbtm1Jmk
(involves: 129S6/SvEvTac)
abnormal cytokine secretion J:109586
decreased T cell proliferation J:109586
Ppp3r1tm2Grc/Ppp3r1tm2.1Grc
Tg(Lck-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal lymph node cell ratio J:89771
abnormal positive T cell selection J:89771
abnormal splenic cell ratio J:89771
Ppp3r1tm2Grc/Ppp3r1tm2Grc
Tg(Lck-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
decreased thymocyte number J:89771
thymus hypoplasia J:89771
Ppp4ctm1Tht/Ppp4ctm1Tht
Tg(Lck-cre)548Jxm/0

(involves: C57BL/6 * CBA)
abnormal positive T cell selection J:117684
abnormal T cell activation J:117684
abnormal T cell differentiation J:117684
decreased CD4-positive, alpha-beta T cell number J:117684
decreased CD8-positive, alpha-beta T cell number J:117684
decreased double-positive T cell number J:117684
decreased single-positive T cell number J:117684
increased double-negative T cell number J:117684
Ppp4ctm1Tht/Ppp4ctm1Tht
Tg(Lck-cre)548Jxm/0
Tg(TcraTcrb)425Cbn/0

(involves: BALB/c * C57BL/6 * CBA)
abnormal positive T cell selection J:117684
decreased double-positive T cell number J:117684
decreased single-positive T cell number J:117684
Ppp4r3btm1b(EUCOMM)Hmgu/Ppp4r3btm1b(EUCOMM)Hmgu
(C57BL/6N-Ppp4r3btm1b(EUCOMM)Hmgu/Ieg)
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Ppp5ctm1.2Rhon/Ppp5ctm1.2Rhon
(B6.129X1-Ppp5ctm1.2Rhon)
enlarged spleen J:178164
Ppp5ctm1a(EUCOMM)Wtsi/Ppp5ctm1a(EUCOMM)Wtsi
(involves: C57BL/6 * C57BL/6N)
increased CD4-positive, alpha-beta T cell number J:213427
increased CD8-positive, alpha-beta T cell number J:213427
increased T cell number J:213427
lymphoid hyperplasia J:213427
Ppp6ctm1Shma/Ppp6ctm1Shma
Tg(KRT14-cre/ERT)20Efu/0

(involves: C57BL/6 * CBA * CD-1)
increased susceptibility to chemically induced skin inflammation J:231809
Ppt1tm1.1Dprc/Ppt1tm1.1Dprc
(involves: 129S6/SvEvTac * BALB/cJ * C57BL/6)
abnormal microglial cell activation J:213552
Ppt1tm1Aj/Ppt1tm1Aj
(involves: 129S4/SvJae * C57BL/6)
abnormal spleen morphology J:95522
brain inflammation J:95522
Ppt1tm1Hof/Ppt1tm1Hof
(involves: 129S6/SvEvTac * C57BL/6J)
microgliosis J:280337
Ppt1tm1Hof/Ppt1tm1Hof
(involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac * C57BL/6)
abnormal cytokine level J:177265
brain inflammation J:177265
Ppt2tm1Hof/Ppt2tm1Hof
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal spleen morphology J:86202
decreased spleen B cell follicle number J:86202
enlarged spleen J:86202
increased macrophage cell number J:86202
increased spleen weight J:86202
Pram1tm1Gak/Pram1tm1Gak
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal neutrophil physiology J:95253
Pramel1em1(IMPC)Tcp/Pramel1em1(IMPC)Tcp
(C57BL/6NCrl-Pramel1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Pramel12em1(IMPC)Mbp/Pramel12em1(IMPC)Mbp
(C57BL/6N-Pramel12em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Prap1tm1Lex/Prap1tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal humoral immune response J:171883
increased immunoglobulin level J:171883
Prap1tm1Lex/Prap1tm1Lex
(B6.129S5-Prap1tm1Lex)
increased circulating interleukin-2 level J:304152
increased circulating interleukin-4 level J:304152
increased circulating interleukin-12 level J:304152
increased inflammatory response J:304152
increased interleukin-12b secretion J:304152
Prcdtm1Vya/Prcdtm1Vya
(B6.Cg-Prcdtm1Vya)
increased microglial cell activation J:276708
Prdm1tm1.1Liz/Prdm1tm1.1Liz
(involves: 129S/SvEv)
abnormal splenocyte physiology J:163979
absent plasma cells J:196531
Prdm1tm1Clme/Prdm1tm1Clme
Tg(Itgax-cre)1-1Reiz/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
abnormal CD4-positive, alpha-beta T cell physiology J:178876
abnormal germinal center B cell physiology J:178876
abnormal immune system physiology J:178876
abnormal T follicular helper cell differentiation J:178876
increased anti-double stranded DNA antibody level J:178876
increased anti-nuclear antigen antibody level J:178876
increased autoantibody level J:178876
increased germinal center B cell number J:178876
increased IgG level J:178876
increased immunoglobulin level J:178876
increased interleukin-6 secretion J:178876
increased spleen germinal center number J:178876
increased splenocyte number J:178876
increased T follicular helper cell number J:178876
kidney inflammation J:178876
Prdm1tm2.1Liz/Prdm1tm2.1Liz
(involves: 129S/SvEv)
immune system phenotype J:153979
Prdm1tm2.1Nutt/Prdm1tm2.1Nutt
Tg(Lck-cre)1Cwi/?

(involves: C57BL/6)
increased susceptibility to Orthomyxoviridae infection J:151858
Prdm1tm3.1Liz/Prdm1tm3.1Liz
(involves: 129S/SvEv)
immune system phenotype J:196531
Prdm4tm1b(EUCOMM)Hmgu/Prdm4tm1b(EUCOMM)Hmgu
(C57BL/6N-Prdm4tm1b(EUCOMM)Hmgu/H)
absent spleen J:211773
Prdm8em1(IMPC)Wtsi/Prdm8+
(C57BL/6N-Prdm8em1(IMPC)Wtsi/Wtsi)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small spleen J:211773
Prdm8em1(IMPC)Wtsi/Prdm8em1(IMPC)Wtsi
(C57BL/6N-Prdm8em1(IMPC)Wtsi/Wtsi)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Prdm11tm1.1Ahl/Prdm11tm1.1Ahl
(B6.129(C)-Prdm11tm1.1Ahl)
abnormal humoral immune response J:233986
decreased CD4-positive, alpha-beta T cell number J:233986
decreased neutrophil cell number J:233986
increased B cell number J:233986
increased interferon-gamma secretion J:233986
increased interleukin-2 secretion J:233986
Prdm13em1(IMPC)Tcp/Prdm13em1(IMPC)Tcp
(C57BL/6NCrl-Prdm13em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
increased spleen weight J:211773
Prdm14tm1a(EUCOMM)Wtsi/Prdm14tm1a(EUCOMM)Wtsi
(C57BL/6N-Prdm14tm1a(EUCOMM)Wtsi/Bay)
increased effector memory T-helper cell number J:211773
Prdm16Gt(OST67423)Lex/Prdm16+
(involves: 129S5/SvEvBrd * C57BL/6J)
increased leukocyte cell number J:103485
Prdm16tm1.1Brsp/Prdm16tm1.1Brsp
Tg(Adipoq-cre)1Evdr/0

(involves: 129/Sv * C57BL/6 * FVB/N)
increased macrophage cell number J:208683
Prdt1CAST/EiJH/Prdt1CAST/EiJH
(involves: CAST/Ei * NZW/OlaHsd)
decreased susceptibility to prion infection J:80787
Prdt1NZW/OlaHsd/Prdt1NZW/OlaHsd
(involves: CAST/Ei * NZW/OlaHsd)
increased susceptibility to prion infection J:80787
Prdt3CAST/EiJH/Prdt3CAST/EiJH
(involves: CAST/Ei * NZW/OlaHsd)
decreased susceptibility to prion infection J:80787
Prdt3NZW/OlaHsd/Prdt3NZW/OlaHsd
(involves: CAST/Ei * NZW/OlaHsd)
increased susceptibility to prion infection J:80787
Prdx1flro/Prdx1flro
(C57BL/10JAnu-Prdx1flro/AnuApb)
abnormal lymphocyte morphology J:104190
Prdx1tm1Rave/Prdx1tm1Rave
(involves: 129S6/SvEvTac * C57BL/6)
abnormal NK T cell number J:84677
abnormal spleen morphology J:84677
enlarged spleen J:84677
impaired natural killer cell mediated cytotoxicity J:84677
increased spleen weight J:84677
Prdx2tm1Yu/Prdx2tm1Yu
(involves: 129S4/SvJae)
enlarged spleen J:84271
increased spleen red pulp amount J:84271
increased spleen weight J:84271
Prdx3Gt(Betageo-puro)711Lex/Prdx3Gt(Betageo-puro)711Lex
(involves: 129S5/SvEvBrd * C57BL/6)
lung inflammation J:118595
Prdx5tm1.1(KOMP)Vlcg/Prdx5tm1.1(KOMP)Vlcg
(involves: C57BL/6J * C57BL/6NTac)
immune system phenotype J:271141
increased circulating interleukin-12b level J:271141
increased circulating tumor necrosis factor level J:271141
increased interleukin-6 secretion J:271141
increased interleukin-12b secretion J:271141
increased tumor necrosis factor secretion J:271141
PrepGt(RRM213)Byg/Prep+
(B6.129P2-PrepGt(RRM213)Byg)
increased spleen weight J:151643
Prex1tm1Dwu/Prex1tm1Dwu
(Not Specified)
impaired neutrophil chemotaxis J:102213
Prex1tm1Hcew/Prex1tm1Hcew
(involves: 129P2/OlaHsd * C57BL/6)
impaired neutrophil chemotaxis J:102214
impaired neutrophil recruitment J:102214
increased neutrophil cell number J:102214
Prf1m1Btlr/Prf1m1Btlr
(C57BL/6J-Prf1m1Btlr)
increased susceptibility to Herpesvirales infection J:216044
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:216044
Prf1tm1Clrk/Prf1tm1Clrk
(involves: 129S7/SvEvBrd * C57BL/6)
decreased cytotoxic T cell cytolysis J:21531
immune system phenotype J:21531
increased susceptibility to Riboviria infection J:21531
Prf1tm1Clrk/Prf1tm1Clrk
(C.129S7(B6)-Prf1tm1Clrk)
abnormal cytokine secretion J:71576
immune system phenotype J:71576
increased activated T cell number J:71576
increased interferon-gamma secretion J:71576
increased susceptibility to Riboviria infection J:71576
increased tumor necrosis factor secretion J:71576
Prf1tm1Clrk/Prf1tm1Clrk
(involves: 129S7/SvEvBrd * BALB/c * NOD)
decreased susceptibility to autoimmune diabetes J:64051
Prf1tm1Clrk/Prf1tm1Clrk
Tg(INS-Il10)#Sar/0

(involves: 129S7/SvEvBrd * BALB/c * NOD)
decreased susceptibility to autoimmune diabetes J:64051
Prf1tm1Sdz/Prf1+
(NOD.B6-Prf1tm1Sdz)
decreased susceptibility to autoimmune diabetes J:43468
insulitis J:43468
periinsulitis J:43468
Prf1tm1Sdz/Prf1+
(A.B6-Prf1tm1Sdz)
impaired natural killer cell mediated cytotoxicity J:211842
Prf1tm1Sdz/Prf1tm1Sdz
(C57BL/6-Prf1tm1Sdz)
abnormal inflammatory response J:17986
abnormal leukocyte physiology J:17986
abnormal NK cell physiology J:113213
decreased cytotoxic T cell cytolysis J:17986
impaired natural killer cell mediated cytotoxicity J:17986
increased interleukin-10 secretion J:123934
increased susceptibility to bacterial infection J:123934
increased susceptibility to infection J:17986
increased susceptibility to parasitic infection J:81397
increased susceptibility to Riboviria infection J:17986
Prf1tm1Sdz/Prf1tm1Sdz
(NOD.B6-Prf1tm1Sdz)
decreased susceptibility to autoimmune diabetes J:43468
insulitis J:43468
periinsulitis J:43468
Prf1tm1Sdz/Prf1tm1Sdz
(C57BL/6-Prf1tm1Sdz/J)
abnormal circulating cytokine level J:92260
abnormal cytotoxic T cell physiology J:193137
abnormal lymph node morphology J:92260
abnormal lymphocyte physiology J:120427
abnormal macrophage activation involved in immune response J:92260
abnormal spleen white pulp morphology J:92260
abnormal T cell activation J:92260
brain inflammation J:92260, J:120427
CNS inflammation J:120427
decreased circulating fibrinogen level J:92260
decreased cytotoxic T cell cytolysis J:193137
decreased interferon-gamma secretion J:92260
decreased leukocyte cell number J:193137
decreased neutrophil cell number J:193137
decreased NK cell degranulation J:193137
immune system phenotype J:120427
increased circulating interferon-alpha level J:92260
increased circulating interferon-gamma level J:92260, J:193137
increased circulating interleukin-1 beta level J:193137
increased circulating interleukin-6 level J:92260, J:193137
increased circulating interleukin-10 level J:92260
increased circulating interleukin-18 level J:92260
increased circulating tumor necrosis factor level J:92260, J:193137
increased spleen red pulp amount J:92260
increased susceptibility to Picornaviridae infection J:120427
increased susceptibility to Riboviria infection J:92260, J:193137
increased susceptibility to Riboviria infection induced morbidity/mortality J:92260
increased susceptibility to viral infection induced morbidity/mortality J:193137
liver inflammation J:92260
lymph node inflammation J:92260
lymph node necrosis J:92260
Prf1tm1Sdz/Prf1tm1Sdz
(involves: BALB/c * C57BL/6)
impaired natural killer cell mediated cytotoxicity J:73948
Prf1tm1Sdz/Prf1tm1Sdz
(A.B6-Prf1tm1Sdz)
impaired natural killer cell mediated cytotoxicity J:211842
Prf1tm1Sdz/Prf1tm1Sdz
Rag1tm1Mom/Rag1tm1Mom

(NOD.Cg-Rag1tm1Mom Prf1tm1Sdz/SzJ)
abnormal response to transplant J:91764
Prf1tm1Sdz/Prf1tm1Sdz
X/Yaa

(BXSB.B6-Prf1tm1Sdz/Dcr)
autoimmune response J:179430
Prf1tm1Tsc/Prf1+
(involves: 129S2/SvPas)
decreased cytotoxic T cell cytolysis J:21731
impaired natural killer cell mediated cytotoxicity J:21731
Prf1tm1Tsc/Prf1tm1Tsc
(involves: 129S2/SvPas)
decreased cytotoxic T cell cytolysis J:21731
decreased susceptibility to bacterial infection J:50903
impaired natural killer cell mediated cytotoxicity J:21731
Prf1tm1Tsc/Prf1tm1Tsc
(129X1.129S2-Prf1tm1Tsc)
abnormal NK cell physiology J:126114
decreased T cell apoptosis J:126114
Prg2tm1Nal/Prg2tm1Nal
(involves: 129P2/OlaHsd * 129X1/SvJ)
abnormal eosinophil morphology J:65655
abnormal inflammatory response J:65655
respiratory system inflammation J:65655
Primpolem1Nki/Primpolem1Nki
(C57BL/6-Primpolem1Nki)
abnormal somatic hypermutation frequency J:242620
immune system phenotype J:242620
Prkaa1tm1Sbj/Prkaa1tm1Sbj
(involves: 129)
increased spleen weight J:147215
Prkaa2tm1b(EUCOMM)Hmgu/Prkaa2tm1b(EUCOMM)Hmgu
(C57BL/6N-Prkaa2tm1b(EUCOMM)Hmgu/H)
enlarged spleen J:211773
Prkab1em1(IMPC)Bay/Prkab1em1(IMPC)Bay
(C57BL/6N-Prkab1em1(IMPC)Bay/Bay)
increased spleen weight J:211773
Prkab1em2(IMPC)Mbp/Prkab1em2(IMPC)Mbp
(C57BL/6N-Prkab1em2(IMPC)Mbp/Ucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Prkab1tm1b(KOMP)Wtsi/Prkab1+
(C57BL/6N-Prkab1tm1b(KOMP)Wtsi/Ccpcz)
decreased Ly6C-positive mature NK cell number J:211773
decreased lymphocyte cell number J:211773
Prkab1tm1b(KOMP)Wtsi/Prkab1tm1b(KOMP)Wtsi
(C57BL/6N-Prkab1tm1b(KOMP)Wtsi/Wtsi)
increased memory-marker CD4-negative NK T cell number J:211773
increased memory-marker gamma-delta T cell number J:211773
Prkab1tm1b(KOMP)Wtsi/Prkab1tm1b(KOMP)Wtsi
(C57BL/6N-Prkab1tm1b(KOMP)Wtsi/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Prkab1tm1b(KOMP)Wtsi/Prkab1tm1b(KOMP)Wtsi
(C57BL/6N-Prkab1tm1b(KOMP)Wtsi/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Prkab1tm1b(KOMP)Wtsi/Prkab1tm1b(KOMP)Wtsi
(C57BL/6N-Prkab1tm1b(KOMP)Wtsi/Bay)
increased spleen weight J:211773
Prkab1tm1b(KOMP)Wtsi/Prkab1tm1b(KOMP)Wtsi
(involves: C57BL/6N)
enlarged spleen J:236972
increased spleen iron level J:236972
increased spleen red pulp amount J:236972
increased spleen weight J:236972
Prkab1tm1b(KOMP)Wtsi/Prkab1tm1b(KOMP)Wtsi
(C57BL/6N-Prkab1tm1b(KOMP)Wtsi/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Prkab1tm1Eihl/Prkab1tm1Eihl
(involves: C57BL/6)
decreased circulating interleukin-6 level J:158295
Prkab2tm1b(EUCOMM)Hmgu/Prkab2+
(C57BL/6N-Prkab2tm1b(EUCOMM)Hmgu/H)
increased eosinophil cell number J:211773
Prkag1tm1.2Mfor/Prkag1tm1.2Mfor
(involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac * FVB/N)
abnormal Kupffer cell morphology J:167779
enlarged spleen J:167779
increased spleen iron level J:167779
increased spleen red pulp amount J:167779
Prkag2tm1.1Geno/Prkag2tm1.1Geno
(B6J.129S(Cg)-Prkag2tm1.1Geno)
abnormal inflammatory response J:235379
white adipose tissue inflammation J:235379
Prkar1atm2Gsm/Prkar1atm2Gsm
Tg(Cr2-cre)3Cgn/0

(involves: 129X1/SvJ * C57BL/6)
abnormal class switch recombination J:147785
Prkar1btm1Gsm/Prkar1btm1Gsm
(Not Specified)
decreased inflammatory response J:43080
PrkcbM1Btlr/Prkcb+
(C57BL/6J-PrkcbM1Btlr)
decreased IgM level J:164864
PrkcbM1Btlr/PrkcbM1Btlr
(C57BL/6J-PrkcbM1Btlr)
decreased IgM level J:164864
PrkcbM1Btlr/PrkcbM1Btlr
(involves: C57BL/6J)
decreased IgM level J:185495
immune system phenotype J:185495
PrkcbM2Btlr/Prkcb+
(C57BL/6J-PrkcbM2Btlr)
decreased IgM level J:217791
decreased response to antigen J:217791
impaired humoral immune response J:217791
PrkcbM2Btlr/PrkcbM2Btlr
(C57BL/6J-PrkcbM2Btlr)
decreased IgM level J:217791
decreased response to antigen J:217791
impaired humoral immune response J:217791
PrkcbM3Btlr/Prkcb+
(C57BL/6J-PrkcbM3Btlr)
decreased IgM level J:217793
decreased response to antigen J:217793
impaired humoral immune response J:217793
PrkcbM3Btlr/PrkcbM3Btlr
(C57BL/6J-PrkcbM3Btlr)
decreased IgM level J:217793
decreased response to antigen J:217793
impaired humoral immune response J:217793
PrkcbM4Btlr/PrkcbM4Btlr
(C57BL/6J-PrkcbM4Btlr)
decreased B-1 B cell number J:274860
increased CD4-positive, alpha-beta T cell number J:274860
increased CD8-positive, alpha-beta T cell number J:274860
increased T cell number J:274860
PrkcbM5Btlr/PrkcbM5Btlr
(C57BL/6J-PrkcbM5Btlr)
decreased IgM level J:274861
impaired humoral immune response J:274861
PrkcbM6Btlr/PrkcbM6Btlr
(C57BL/6J-PrkcbM6Btlr)
decreased B-1 B cell number J:274862
Prkcbtilc/Prkcb+
(involves: C57BL/6JSfdAnu)
abnormal humoral immune response J:221236
decreased IgG3 level J:221236
decreased IgM level J:221236
Prkcbtilc/Prkcbtilc
(C57BL/6JSfdAnu-Prkcbtilc/AnuApb)
decreased IgM level J:104190
Prkcbtilc/Prkcbtilc
(involves: C57BL/6JSfdAnu)
abnormal humoral immune response J:221236
decreased B cell proliferation J:221236
decreased B-1a cell number J:221236
decreased IgG3 level J:221236
decreased IgM level J:221236
immune system phenotype J:221236
Prkcbtm1Tara/Prkcb+
(involves: 129)
abnormal humoral immune response J:34818
decreased IgG3 level J:34818
decreased IgM level J:34818
Prkcbtm1Tara/Prkcbtm1Tara
(involves: 129)
abnormal humoral immune response J:34818
decreased B cell number J:34818
decreased B cell proliferation J:34818
decreased B-1 B cell number J:34818
decreased B-1a cell number J:34818
decreased IgG3 level J:34818
decreased IgM level J:34818
immune system phenotype J:34818
PrkcdM1Btlr/PrkcdM1Btlr
(C57BL/6J-PrkcdM1Btlr)
increased susceptibility to induced colitis J:265145
Prkcdm2Btlr/Prkcdm2Btlr
(C57BL/6J-Prkcdm2Btlr)
enhanced humoral immune response J:265146
increased IgM level J:265146
increased NK cell number J:265146
increased susceptibility to induced colitis J:265146
Prkcdtm1.1Chou/Prkcdtm1.1Chou
(involves: C57BL/6 * C57BL/6NTac)
abnormal neutrophil physiology J:217880
Prkcdtm1Kin/Prkcdtm1Kin
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immunoglobulin level J:143854
abnormal lymph node germinal center morphology J:76135
abnormal Peyer's patch germinal center morphology J:76135
abnormal plasma cell differentiation J:143854
enlarged lymph nodes J:76135
enlarged spleen J:76135
glomerulonephritis J:76135
increased acute inflammation J:76135
increased anti-chromatin antibody level J:76135
increased B cell number J:76135
increased B cell proliferation J:76135, J:143854
increased follicular B cell number J:143854
increased IgA level J:76135, J:143854
increased IgG1 level J:76135, J:143854
increased IgM level J:143854
increased interleukin-6 secretion J:76135
increased marginal zone B cell number J:143854
increased spleen germinal center number J:76135
increased transitional stage B cell number J:143854
Prkcdtm1Msg/Prkcdtm1Msg
(involves: 129X1/SvJ * C57BL/6J)
abnormal neutrophil physiology J:91377
decreased neutrophil cell number J:91377
Prkcdtm1Qxu/Prkcdtm1Qxu
(involves: 129P2/OlaHsd)
abnormal response to transplant J:78680
Prkcdtm1Qxu/Prkcdtm1Qxu
(involves: 129P2/OlaHsd * C57BL/6)
enlarged lymph nodes J:76134
enlarged spleen J:76134
immune system phenotype J:76134
increased anti-nuclear antigen antibody level J:76134
increased B cell apoptosis J:76134
increased B cell number J:76134
increased IgA level J:76134
increased IgG1 level J:76134
increased IgM level J:76134
Prkcdtm1Qxu/Prkcdtm1Qxu
Tg(IghelMD4)4Ccg/0
Tg(KLK4mHEL)6Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:76134
Prkcdtm1Qxu/Prkcdtm1Qxu
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:76134
abnormal B cell proliferation J:76134
abnormal self tolerance J:76134
abnormal spleen primary B follicle morphology J:76134
autoimmune response J:76134
decreased B cell number J:76134
immune system phenotype J:76134
increased spleen germinal center number J:76134
Prkcem1Btlr/Prkcem1Btlr
(C57BL/6J-Prkcem1Btlr)
decreased dendritic cell number J:267703
decreased NK cell number J:267703
Prkcetm1Bai/Prkcetm1Bai
(Not Specified)
immune system phenotype J:94663
Prkcetm1Bsca/Prkcetm1Bsca
(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating interleukin-1 beta level J:103337
decreased circulating tumor necrosis factor level J:103337
decreased macrophage apoptosis J:103337
decreased macrophage nitric oxide production J:103337
decreased T cell proliferation J:103337
increased susceptibility to bacterial infection J:103337
Prkcetm1Ltg/Prkcetm1Ltg
(involves: 129P2/OlaHsd * FVB/N)
decreased tumor necrosis factor secretion J:86056
Prkcgtm1Stl/Prkcgtm1Stl
(Not Specified)
decreased inflammatory response J:25061
Prkchtm1.2Gasc/Prkchtm1.2Gasc
(involves: C57BL/6 * FVB/N * SJL)
abnormal brachial lymph node morphology J:186080
abnormal cervical lymph node morphology J:186080
abnormal effector T cell morphology J:186080
abnormal lymph node morphology J:186080
decreased B cell number J:186080
decreased CD4-positive, alpha-beta T cell number J:186080
decreased CD8-positive, alpha-beta T cell number J:186080
decreased DN1 thymic pro-T cell number J:186080
decreased DN4 thymocyte number J:186080
decreased double-positive T cell number J:186080
decreased lymphocyte cell number J:186080
decreased T cell number J:186080
decreased T cell proliferation J:186080
enlarged axillary lymph nodes J:186080
enlarged cervical lymph nodes J:186080
enlarged inguinal lymph nodes J:186080
enlarged lymph nodes J:186080
increased B cell number J:186080
increased CD4-positive, alpha-beta T cell number J:186080
increased CD8-positive, alpha-beta T cell number J:186080
increased memory T cell number J:186080
increased T cell number J:186080
thymus hypoplasia J:186080
Prkchtm1.2Gasc/Prkchtm1.2Gasc
Prkcqtm1Litt/Prkcqtm1Litt

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL)
abnormal positive T cell selection J:186080
decreased CD4-positive, alpha-beta T cell number J:186080
decreased CD8-positive, alpha-beta T cell number J:186080
decreased DN1 thymic pro-T cell number J:186080
decreased DN4 thymocyte number J:186080
decreased double-negative T cell number J:186080
decreased double-positive T cell number J:186080
decreased T cell proliferation J:186080
immune system phenotype J:186080
Prkcitm1Rfar/Prkci+
Tg(Ckmm-cre)5Khn/?

(involves: 129P2/OlaHsd * C57BL/6 * FVB)
increased susceptibility to autoimmune diabetes J:123964
Prkcqm1Btlr/Prkcqm1Btlr
(C57BL/6J-Prkcqm1Btlr)
decreased IgG level J:255214
impaired humoral immune response J:255214
Prkcqm2Btlr/Prkcqm2Btlr
(C57BL/6J-Prkcqm2Btlr)
decreased IgG level J:255216
impaired humoral immune response J:255216
Prkcqtm1.1Bai/Prkcqtm1.1Bai
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal T cell physiology J:83733
decreased interleukin-2 secretion J:83733
decreased T cell proliferation J:83733
Prkcqtm1Litt/Prkcqtm1Litt
(involves: 129P2/OlaHsd)
abnormal T cell activation J:83922
decreased interleukin-2 secretion J:83922
decreased T cell proliferation J:83922, J:123989
immune system phenotype J:123989
Prkcqtm1Litt/Prkcqtm1Litt
(B6.129P2-Prkcqtm1Litt)
abnormal CD4-positive, alpha-beta T cell physiology J:94285
abnormal T-helper 1 cell differentiation J:94285
abnormal T-helper 2 physiology J:94285
decreased interferon-gamma secretion J:129421, J:94285
decreased interleukin-2 secretion J:129421, J:94285
decreased interleukin-4 secretion J:129421, J:94285
decreased interleukin-5 secretion J:94285
decreased interleukin-13 secretion J:94285
decreased interleukin-17 secretion J:129421
decreased splenocyte proliferation J:129421
decreased susceptibility to experimental autoimmune encephalomyelitis J:129421
decreased T cell proliferation J:94285
immune system phenotype J:94285
Prkcqtm1Litt/Prkcqtm1Litt
(involves: 129P2/OlaHsd * C57BL/6)
abnormal effector T cell morphology J:186080
abnormal positive T cell selection J:186080
decreased CD4-positive, alpha-beta T cell number J:186080
decreased CD8-positive, alpha-beta T cell number J:186080
decreased DN1 thymic pro-T cell number J:186080
decreased NK T cell number J:141128
decreased T cell proliferation J:186080
immune system phenotype J:141128
increased T cell apoptosis J:141128
Prkcqtm1Litt/Prkcqtm1Litt
(either: (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal response to infection J:141930
decreased T cell apoptosis J:141930
decreased T cell proliferation J:141930
Prkcqtm1Litt/Prkcqtm1Litt
Tcratm1Mom/Tcratm1Mom

(involves: 129P2/OlaHsd * 129S2/SvPas)
decreased interleukin-4 secretion J:135589
decreased T cell proliferation J:135589
immune system phenotype J:135589
Prkcqtm1Litt/Prkcqtm1Litt
Tg(DO11.10)10Dlo/0

(involves: 129 * BALB/c * C3H * C57BL/6)
decreased T cell apoptosis J:141930
Prkcqtm1Litt/Prkcqtm1Litt
Tg(Lck-Notch3)#Issc/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
enlarged spleen J:96010
increased spleen weight J:96010
Prkcqtm1Litt/Prkcqtm1Litt
Tg(LCKprBCL2L1)12Sjk/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased NK T cell number J:141128
immune system phenotype J:141128
Prkcqtm1Litt/Prkcqtm1Litt
Tg(TcrLCMV)327Sdz/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal T cell anergy J:123989
decreased cytotoxic T cell cytolysis J:123989
decreased splenocyte proliferation J:123989
decreased T cell proliferation J:123989
Prkcztm1Jmos/Prkcztm1Jmos
(involves: 129P2/OlaHsd * 129/Sv)
abnormal Peyer's patch follicle morphology J:72720
abnormal Peyer's patch morphology J:72720
abnormal spleen marginal zone morphology J:72720
decreased B cell number J:72720
decreased spleen B cell follicle size J:72720
immune system phenotype J:72720
small Peyer's patches J:72720
Prkd1em2(IMPC)Wtsi/Prkd1+
(C57BL/6N-Prkd1em2(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Prkd2Gt(RRJ380)Byg/Prkd2Gt(RRJ380)Byg
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:166867
Prkd2tm1.1Daca/Prkd2tm1.1Daca
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:166867
abnormal CD8-positive, alpha-beta T cell physiology J:166867
decreased IgG1 level J:166867
decreased IgM level J:166867
decreased interferon-gamma secretion J:166867
decreased interleukin-2 secretion J:166867
immune system phenotype J:166867
Prkd2tm1.1Shoy/Prkd2tm1.1Shoy
Prkd3tm1.1Shoy/Prkd3tm1.1Shoy
Tg(BCL2)25Wehi/0
Tg(Lck-cre)1Jtak/0

(involves: 129 * C57BL/6 * C57BL/6JWehi * SJL/JWehi)
decreased thymocyte number J:236298
Prkd2tm1.1Shoy/Prkd2tm1.1Shoy
Prkd3tm1.1Shoy/Prkd3tm1.1Shoy
Tg(Lck-cre)1Jtak/0

(involves: 129 * C57BL/6)
decreased thymocyte number J:236298
small thymus medulla J:236298
Prkd2tm1.1Shoy/Prkd2tm1.1Shoy
Prkd3tm1.1Shoy/Prkd3tm1.1Shoy
Tg(Lck-cre)1Jtak/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129 * C57BL/6 * C57BL/6J * DBA/2J)
decreased thymocyte number J:236298
increased double-positive T cell number J:236298
Prkd2tm1.1Shoy/Prkd2tm1.1Shoy
Prkd3tm1.1Shoy/Prkd3tm1.1Shoy
Tg(Lck-cre)1Jtak/0
Tg(TcraTcrb)425Cbn/0

(involves: 129 * BALB/c * C57BL/6)
decreased thymocyte number J:236298
Prkd2tm1.1Shoy/Prkd2tm1.1Shoy
Prkd3tm1.1Shoy/Prkd3tm1.1Shoy
Tg(Lck-cre)1Jtak/0
Tg(TcraTcrb)1100Mjb/0

(involves: 129 * C57BL/6)
decreased thymocyte number J:236298
Prkd2tm1.1Shoy/Prkd2tm1.1Shoy
Tg(Lck-cre)1Jtak/0

(involves: 129 * C57BL/6)
immune system phenotype J:236298
Prkdcberty/Prkdcberty
(C57BL/6JAnu-Prkdcberty)
absent B cells J:104190
absent T cells J:104190
Prkdcem2(IMPC)Ics/Prkdcem2(IMPC)Ics
(C57BL/6N-Prkdcem2(IMPC)Ics/Ics)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Prkdchanky/Prkdchanky
(either: C57BL/6JAnu or (involves: C57BL/6JAnu * CBA/CaJ))
cecum inflammation J:104190
colitis J:104190
decreased lymphocyte cell number J:104190
enlarged mesenteric lymph nodes J:104190
increased plasma cell number J:104190
interstitial pneumonia J:104190
liver inflammation J:104190
lymph node hyperplasia J:104190
myeloid hyperplasia J:104190
Prkdcm1Anu/Prkdcm1Anu
(C57BL/6JAnu-Prkdcm1Anu)
abnormal lymphocyte morphology J:104190
Prkdcm1Btlr/Prkdcm1Btlr
(C57BL/6J-Prkdcm1Btlr)
abnormal immune system physiology J:178522
Prkdcm1Btlr/Prkdcm1Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
decreased B cell number J:185495
decreased IgG level J:185495
decreased IgM level J:185495
Prkdcm2Btlr/Prkdcm2Btlr
(C57BL/6J-Prkdcm2Btlr)
abnormal B cell physiology J:204502
decreased B cell number J:204502
decreased CD4-positive, alpha-beta T cell number J:204502
decreased CD8-positive, alpha-beta T cell number J:204502
decreased IgG level J:204502
decreased IgM level J:204502
Prkdcm3Btlr/Prkdcm3Btlr
(C57BL/6J-Prkdcm3Btlr)
decreased IgG level J:224665
impaired humoral immune response J:224665
Prkdcm4Btlr/Prkdcm4Btlr
(C57BL/6J-Prkdcm4Btlr)
decreased B cell number J:255217
increased B-1b cell number J:255217
increased neutrophil cell number J:255217
Prkdcm5Btlr/Prkdcm5Btlr
(C57BL/6J-Prkdcm5Btlr)
increased alpha-beta T cell number J:255220
increased CD4-positive, alpha-beta T cell number J:255220
Prkdcm6Btlr/Prkdcm6Btlr
(C57BL/6J-Prkdcm6Btlr)
decreased CD8-positive, naive alpha-beta T cell number J:255221
increased alpha-beta T cell number J:255221
increased CD4-positive, alpha-beta T cell number J:255221
increased CD8-positive, alpha-beta T cell number J:255221
Prkdcm7Btlr/Prkdcm7Btlr
(C57BL/6J-Prkdcm7Btlr)
abnormal humoral immune response J:255223
decreased IgG level J:255223
increased effector memory CD4-positive, alpha-beta T cell number J:255223
PrkdcM8Btlr/Prkdc+
(C57BL/6J-PrkdcM8Btlr)
decreased CD8-positive, alpha-beta T cell number J:255224
PrkdcM8Btlr/PrkdcM8Btlr
(C57BL/6J-PrkdcM8Btlr)
decreased CD8-positive, alpha-beta T cell number J:255224
increased CD4-positive, alpha-beta T cell number J:255224
increased plasmacytoid dendritic cell number J:255224
PrkdcM9Btlr/Prkdc+
(C57BL/6J-PrkdcM9Btlr)
decreased B-1a cell number J:255268
decreased effector memory CD4-positive, alpha-beta T cell number J:255268
increased B cell number J:255268
increased B-1b cell number J:255268
PrkdcM9Btlr/PrkdcM9Btlr
(C57BL/6J-PrkdcM9Btlr)
decreased B-1a cell number J:255268
decreased effector memory CD4-positive, alpha-beta T cell number J:255268
increased B cell number J:255268
increased B-1b cell number J:255268
PrkdcM10Btlr/Prkdc+
(C57BL/6J-PrkdcM10Btlr)
decreased CD8-positive, alpha-beta T cell number J:255269
PrkdcM10Btlr/PrkdcM10Btlr
(C57BL/6J-PrkdcM10Btlr)
decreased CD8-positive, alpha-beta T cell number J:255269
PrkdcM11Btlr/Prkdc+
(C57BL/6J-PrkdcM11Btlr)
enhanced humoral immune response J:255270
increased IgM level J:255270
PrkdcM11Btlr/PrkdcM11Btlr
(C57BL/6J-PrkdcM11Btlr)
enhanced humoral immune response J:255270
increased IgM level J:255270
Prkdcm12Btlr/Prkdcm12Btlr
(C57BL/6J-Prkdcm12Btlr)
decreased B cell number J:264708
decreased B-1 B cell number J:264708
decreased CD4-positive, alpha-beta T cell number J:264708
decreased CD8-positive, alpha-beta T cell number J:264708
decreased CD8-positive, naive alpha-beta T cell number J:264708
decreased NK T cell number J:264708
decreased single-positive T cell number J:264708
decreased T cell number J:264708
increased central memory CD4-positive, alpha-beta T cell number J:264708
increased central memory CD8 positive, alpha-beta T cell number J:264708
increased effector memory CD4-positive, alpha-beta T cell number J:264708
increased NK cell number J:264708
Prkdcm13Btlr/Prkdcm13Btlr
(C57BL/6J-Prkdcm13Btlr)
increased effector memory CD4-positive, alpha-beta T cell number J:272441
Prkdcm14Btlr/Prkdcm14Btlr
(C57BL/6J-Prkdcm14Btlr)
abnormal CD4-positive T cell differentiation J:272442
PrkdcM15Btlr/PrkdcM15Btlr
(C57BL/6J-PrkdcM15Btlr)
decreased B-1 B cell number J:272445
PrkdcM16Btlr/PrkdcM16Btlr
(C57BL/6J-PrkdcM16Btlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:272520
Prkdcm17Btlr/Prkdcm17Btlr
(C57BL/6J-Prkdcm17Btlr)
increased plasmacytoid dendritic cell number J:272521
Prkdcm18Btlr/Prkdcm18Btlr
(C57BL/6J-Prkdcm18Btlr)
abnormal B cell differentiation J:274730
abnormal CD4-positive T cell differentiation J:274730
abnormal CD8-positive, alpha-beta T cell differentiation J:274730
abnormal T cell differentiation J:274730
decreased alpha-beta T cell number J:274730
decreased B cell number J:274730
decreased B-1 B cell number J:274730
decreased CD4-positive, alpha-beta T cell number J:274730
decreased CD8-positive, alpha-beta T cell number J:274730
decreased CD8-positive, naive alpha-beta T cell number J:274730
increased CD4-positive, alpha-beta T cell number J:274730
increased CD8-positive, alpha-beta T cell number J:274730
increased central memory CD4-positive, alpha-beta T cell number J:274730
increased central memory CD8 positive, alpha-beta T cell number J:274730
increased effector memory CD4-positive, alpha-beta T cell number J:274730
increased effector memory CD8-positive, alpha-beta T cell number J:274730
increased T cell number J:274730
Prkdcm19Btlr/Prkdcm19Btlr
(C57BL/6J-Prkdcm19Btlr)
abnormal B cell differentiation J:274763
abnormal CD4-positive T cell differentiation J:274763
abnormal CD8-positive, alpha-beta T cell differentiation J:274763
abnormal T cell differentiation J:274763
decreased B cell number J:274763
decreased B-1 B cell number J:274763
decreased CD4-positive, alpha-beta T cell number J:274763
decreased CD8-positive, alpha-beta T cell number J:274763
decreased CD8-positive, naive alpha-beta T cell number J:274763
decreased T cell number J:274763
increased central memory CD4-positive, alpha-beta T cell number J:274763
increased central memory CD8 positive, alpha-beta T cell number J:274763
increased effector memory CD4-positive, alpha-beta T cell number J:274763
increased effector memory CD8-positive, alpha-beta T cell number J:274763
increased NK cell number J:274763
Prkdcscid/Prkdcscid
(C.BKa-Prkdcscid)
abnormal humoral immune response J:6958
abnormal response to transplant J:22026
abnormal spleen white pulp morphology J:6958
abnormal thymus morphology J:6958
absent B cells J:6958
absent Peyer's patches J:6958
absent pre-B cells J:6958
absent thymus cortex J:6958
decreased B cell proliferation J:6958
decreased IgG level J:6958
decreased immunoglobulin level J:6958, J:22026
decreased leukocyte cell number J:6958
decreased T cell proliferation J:6958
immune system phenotype J:22026
increased length of allograft survival J:6958, J:22026
lymph node hypoplasia J:6958
lymphoid hypoplasia J:6958
salivary gland inflammation J:21965
small lymphoid organs J:6958
small thymus J:6958
thymus cyst J:6958
Prkdcscid/Prkdcscid
(NOD.Cg-Prkdcscid)
abnormal lymph node morphology J:109833, J:22026
abnormal response to transplant J:109833, J:22026
abnormal spleen white pulp morphology J:109833, J:22026
abnormal thymus corticomedullary boundary morphology J:22026
abnormal thymus lobule morphology J:22026
decreased B cell number J:22026
decreased CD4-positive, alpha-beta T cell number J:109833, J:22026
decreased CD8-positive, alpha-beta T cell number J:109833, J:22026
decreased immunoglobulin level J:22026
decreased level of surface class I molecules J:22026
decreased lymphocyte cell number J:22026
decreased mature B cell number J:109833
decreased NK cell number J:22026
decreased pre-B cell number J:22026
decreased T cell number J:22026
impaired complement classical pathway J:22026
impaired natural killer cell mediated cytotoxicity J:22026
increased granulocyte number J:22026
increased length of allograft survival J:22026
increased macrophage cell number J:22026
spleen hypoplasia J:109833, J:22026
thymus cyst J:22026
Prkdcscid/Prkdcscid
(B6.Cg-Prkdcscid/Sz)
abnormal complement pathway J:34814, J:22026
abnormal level of surface class II molecules J:34814
abnormal lymph node B cell domain morphology J:34814
abnormal NK cell physiology J:34814
abnormal Peyer's patch morphology J:34814
abnormal spleen white pulp morphology J:34814
abnormal thymus morphology J:34814
decreased B cell number J:34814
decreased CD4-positive, alpha-beta T cell number J:34814
decreased CD8-positive, alpha-beta T cell number J:34814
decreased immunoglobulin level J:34814
decreased lymphocyte cell number J:34814
decreased pre-B cell number J:34814
decreased T cell number J:34814
increased eosinophil cell number J:34814
increased granulocyte number J:34814
increased macrophage cell number J:34814
increased monocyte cell number J:34814
increased neutrophil cell number J:34814
increased NK cell number J:34814
small Peyer's patches J:34814
small thymus J:34814
spleen hypoplasia J:34814
stomach inflammation J:120556
thymus cyst J:34814
Prkdcscid/Prkdcscid
(NOD.Cg-Prkdcscid/J)
abnormal response to transplant J:91764
Prkdcscid/Prkdcscid
(involves: BALB/c * C57BL/6 * C57BL/Ka)
abnormal NK cell physiology J:115033
Prkdcscid/Prkdcscid
Mcph1Tg(HLA-A2.1)1Enge/Mcph1+

(NOD.Cg-Mcph1Tg(HLA-A2.1)1Enge Prkdcscid/Dvs)
abnormal splenocyte morphology J:91764
Prkdcscid/Prkdcscid
Rasa3scat/Rasa3scat

(involves: BALB/c * BALB/cBy * C57BL)
abnormal immune system morphology J:186485
Prkdcscid/Prkdcscid
Sst1C57BL/6J/Sst1C57BL/6J

(involves: C3HeB/FeJ * C57BL/6J)
decreased susceptibility to bacterial infection J:93705
Prkdcscid/Prkdcscid
Tg(B2M)55Hpl/0
Mcph1Tg(HLA-A2.1)1Enge/Mcph1+

(NOD.Cg-Mcph1Tg(HLA-A2.1)1Enge Prkdcscid Tg(B2M)55Hpl/Sz)
abnormal response to transplant J:91764
Prkdcscid/Prkdcscid
Tg(CSF2)2Ygy/0
Tg(IL3)1Ygy/0

(CB17.Cg-Prkdcscid Tg(CSF2)2Ygy Tg(IL3)1Ygy)
abnormal response to transplant J:94302
Prkdcscid/Prkdcscid
Tg(CSF2)2Ygy/0
Tg(IL3)1Ygy/0
Tg(KITLG)3Ygy/0

(CB17.Cg-Prkdcscid Tg(CSF2)2Ygy Tg(IL3)1Ygy Tg(KITLG)3Ygy)
abnormal response to transplant J:106416, J:94302
Prkdcscid/Prkdcscid
Tg(CSF2)2Ygy/0
Tg(IL3)1Ygy/0
Tg(KITLG)3Ygy/0

(NOD.Cg-Prkdcscid Tg(CSF2)2Ygy Tg(IL3)1Ygy Tg(KITLG)3Ygy)
abnormal response to transplant J:107052
decreased susceptibility to graft versus host disease J:107052
Prkdcscid/Prkdcscid
Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz/Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz

(NOD.Cg-Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz Prkdcscid/Gck)
abnormal professional antigen presenting cell morphology J:126700
absent T cells J:126700
Prkdcscid/Prkdcscid
Tg(Ins2-Fasl)24Ach/0

(NOD.Cg-Prkdcscid Tg(Ins2-Fasl)24Ach)
decreased susceptibility to autoimmune diabetes J:81416
increased susceptibility to autoimmune diabetes J:81416
Prkdcscid/Prkdcscid
Tg(INS-Il10)#Sar/0

(NOD.Cg-Prkdcscid Tg(INS-Il10)#Sar)
increased susceptibility to autoimmune diabetes J:66103
Prkdcscid/Prkdcscid
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0

(NOD.Cg-Prkdcscid Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs)
abnormal CD4-positive, alpha beta T cell morphology J:93553
increased susceptibility to autoimmune diabetes J:93553
Prkdcscid/Prkdcscid
Tg(Tcrb)93Vbo/0

(involves: Balb/c * C57BL/Ka * C57BL/Lia * CBA/BrA)
abnormal CD4-positive, alpha beta T cell morphology J:111476
abnormal CD8-positive, alpha beta T cell morphology J:111476
abnormal double-positive T cell morphology J:111476
abnormal single-positive T cell number J:111476
abnormal T cell differentiation J:111476
Prkdcscid/Prkdcscid
Tg(TcrLCMV)327Sdz/?

(NOD.Cg-Emv30b Prkdcscid Tg(TcrLCMV)327Sdz/DvsJ)
immune system phenotype J:71050
Prkdcscid/Prkdcscid
Tgfb1tm1Doe/Tgfb1tm1Doe

(involves: 129 * C3H * CF-1)
decreased spleen weight J:129629
PrkdcTg(INS-PDE2)5-1Lmb/?
(involves: FVB/N)
abnormal thymus morphology J:108405
Prkdctm1.1Bpcc/Prkdctm1.1Bpcc
(involves: 129 * C57BL/6)
abnormal immunoglobulin V(D)J recombination J:171351
arrested B cell differentiation J:171351
decreased CD4-positive, alpha-beta T cell number J:171351
decreased CD8-positive, alpha-beta T cell number J:171351
decreased double-negative T cell number J:171351
decreased double-positive T cell number J:171351
decreased gamma-delta T cell number J:171351
decreased granulocyte number J:171351
decreased leukocyte cell number J:171351
decreased lymphocyte cell number J:171351
decreased macrophage cell number J:171351
decreased mature B cell number J:171351
decreased T cell number J:171351
small lymphoid organs J:171351
Prkdctm1Fwa/Prkdctm1Fwa
(involves: 129S6/SvEvTac * C57BL/6)
abnormal T cell receptor beta chain V(D)J recombination J:50221
abnormal T cell receptor V(D)J recombination J:50221
absent pre-B cells J:50221
arrested B cell differentiation J:50221
arrested T cell differentiation J:50221
decreased double-positive T cell number J:50221
decreased thymocyte number J:50221
Prkdctm1Fwa/Prkdctm1Fwa
(involves: 129S6/SvEvTac)
decreased splenocyte number J:306598
Prkdctm1Gcl/Prkdctm1Gcl
(involves: 129S1/Sv * C57BL/6)
abnormal immunoglobulin heavy chain V(D)J recombination J:53765
abnormal lymph node morphology J:53765
abnormal spleen morphology J:53765
abnormal T cell receptor beta chain V(D)J recombination J:53765
abnormal T cell receptor delta chain V(D)J recombination J:53765
absent mature B cells J:53765
absent Peyer's patches J:53765
absent thymus corticomedullary boundary J:53765
arrested B cell differentiation J:53765
small lymph nodes J:53765
small Peyer's patches J:53765
small spleen J:53765
small thymus J:53765
thymus hypoplasia J:53765
Prkdctm1Gcl/Prkdctm1Gcl
(involves: 129S1/Sv)
decreased thymocyte apoptosis J:126920
Prkdctm1Get/Prkdctm1Get
(involves: 129S4/SvJae * Black Swiss)
abnormal B cell differentiation J:50222
abnormal immunoglobulin heavy chain V(D)J recombination J:50222
abnormal immunoglobulin light chain V-J recombination J:50222
abnormal T cell differentiation J:50222
abnormal T cell number J:50222
abnormal T cell receptor alpha chain V-J recombination J:50222
abnormal T cell receptor beta chain V(D)J recombination J:50222
abnormal T cell receptor delta chain V(D)J recombination J:50222
abnormal thymus corticomedullary boundary morphology J:50222
arrested B cell differentiation J:50222
arrested T cell differentiation J:50222
decreased IgM level J:50222
decreased single-positive T cell number J:50222
decreased spleen white pulp amount J:50222
increased double-negative T cell number J:50222
increased double-positive T cell number J:50222
increased NK cell number J:50222
small lymph nodes J:50222
spleen hypoplasia J:50222
thymus hypoplasia J:50222
Prkg1tm1b(KOMP)Wtsi/Prkg1tm1b(KOMP)Wtsi
(C57BL/6N-Prkg1tm1b(KOMP)Wtsi/H)
enlarged spleen J:211773
Prkg1tm2.1Naw/Prkg1tm2.1Naw
(involves: 129S1/Sv * 129X1/SvJ)
enlarged spleen J:134639
Prl7d1em1(IMPC)Tcp/Prl7d1em1(IMPC)Tcp
(C57BL/6NCrl-Prl7d1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Prl7d1em1Liga/Prl7d1em1Liga
(involves: C57BL/6)
increased uterine NK cell number J:288761
Prltm1Hmn/Prltm1Hmn
(involves: 129S2/SvPas)
immune system phenotype J:45243
Prmt3tm1a(EUCOMM)Wtsi/Prmt3tm1a(EUCOMM)Wtsi
(involves: C57BL/6 * C57BL/6N)
increased CD4-positive, alpha-beta T cell number J:213427
increased CD8-positive, alpha-beta T cell number J:213427
increased incidence of corneal inflammation J:213427
increased T cell number J:213427
Prmt7tm1a(EUCOMM)Wtsi/Prmt7tm1a(EUCOMM)Wtsi
(B6JTyr;B6N-Prmt7tm1a(EUCOMM)Wtsi/Wtsi)
abnormal thymus topology J:239583
blood in lymph vessels J:239583
Prmt9em1Cya/Prmt9em1Cya
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6N)
decreased susceptibility to viral infection J:328263
increased circulating interferon-beta level J:328263
increased interferon-beta secretion J:328263
Prnp/Prndtm1Aag/Prnp/Prndtm1Aag
(Not Specified)
immune system phenotype J:89232
Prnp/Prndtm1Aag/Prnp/Prndtm1Aag
(Not Specified)
immune system phenotype J:89232
Prnpa/Prnpa
(NZW)
increased susceptibility to prion infection J:8918
Prnpb/Prnpb
(I/LnJ)
decreased susceptibility to prion infection J:8918
Prnpc/Prnpc
(MAI/Pas)
decreased susceptibility to prion infection J:90099
Prnptm1(PRNP)Tkit/Prnptm1(PRNP)Tkit
(Not Specified)
decreased susceptibility to prion infection J:86603
increased susceptibility to prion infection J:86603
Prnptm1Cwe/Prnptm1Cwe
Tg(Lck-Prnp)33Cwe/0

(involves: 129S7/SvEvBrd * C57BL/6)
increased CD8-positive, alpha-beta T cell number J:129512
increased gamma-delta T cell number J:129512
thymus hypoplasia J:129512
Prnptm1Cwe/Prnptm1Cwe
Tg(Nefh-cre)22Jcol/?
Tg(Prnp)37Jcol/?

(involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB)
decreased susceptibility to prion infection J:126424
Prnptm1Cwe/Prnptm1Cwe
Tg(Nefh-cre)22Jcol/?
Tg(Prnp)46Jcol/?

(involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB)
decreased susceptibility to prion infection J:74652
Prnptm1Cwe/Prnptm1Cwe
Tg(PRNP)35Jcol/Tg(PRNP)35Jcol

(involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N)
increased susceptibility to prion infection J:131494
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp)37Jcol/?

(involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB)
increased susceptibility to prion infection J:74652, J:126424
Prnptm1Cwe/Prnptm1Cwe
Tg(PRNP)45Jcol/Tg(PRNP)45Jcol

(involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N)
increased susceptibility to prion infection J:131494
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp)46Jcol/?

(involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB)
immune system phenotype J:74652
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp)4053Sbp/0

(involves: 129S7/SvEvBrd * FVB/N)
increased susceptibility to prion infection J:136434
Prnptm1Cwe/Prnptm1Cwe
Tg(PRNP)23454Sbp/0

(involves: 129S7/SvEvBrd * FVB/N)
increased susceptibility to prion infection J:236012
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp)a19Cwe/0

(Not Specified)
increased susceptibility to prion infection J:32214
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp)a20Cwe/0

(Not Specified)
increased susceptibility to prion infection J:32214
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp)a20Cwe/0

(involves: 129S7/SvEvBrd * C57BL/6)
abnormal B cell morphology J:129512
abnormal T cell differentiation J:129512
decreased CD4-positive, alpha-beta T cell number J:129512
decreased CD8-positive, alpha-beta T cell number J:129512
decreased DN2 thymocyte number J:129512
decreased DN4 thymocyte number J:129512
decreased double-positive T cell number J:129512
decreased thymocyte number J:129512
increased DN3 thymocyte number J:129512
increased double-negative T cell number J:129512
increased gamma-delta T cell number J:129512
thymus atrophy J:129512
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp)c35Cwe/0

(Not Specified)
increased susceptibility to prion infection J:32214
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp*S170N*N174T)1020Aag/0

(involves: 129S7/SvEvBrd * C57BL/6)
decreased susceptibility to prion infection J:143528
microgliosis J:143528
Prnptm1Edin/Prnptm1Edin
(129P2/OlaHsd-Prnptm1Edin/EdinH)
abnormal susceptibility to prion infection J:58820
Prnptm1Lnq/Prnptm1Lnq
(involves: 129P2/OlaHsd * C57BL/6N)
decreased susceptibility to prion infection J:154937
Prnptm1Miy/Prnptm1Miy
(involves: 129S4/SvJae * C57BL/6)
decreased susceptibility to prion infection J:69186
Prnptm1Rcm/Prnptm1Rcm
(129P2/OlaHsd-Prnptm1Rcm)
abnormal susceptibility to prion infection J:45908
Prnptm1Tuzi/Prnp+
(involves: 129P2/OlaHsd)
decreased susceptibility to prion infection J:92302
Prnptm1Tuzi/Prnp+
Tg(CMV-cre)1Cgn/?

(involves: 129P2/OlaHsd * BALB/cJ)
immune system phenotype J:92302
Prnptm1Tuzi/Prnptm2Edin
(involves: 129P2/OlaHsd)
decreased susceptibility to prion infection J:92302
Prnptm1Tuzi/Prnptm2Edin
Tg(CMV-cre)1Cgn/?

(involves: 129P2/OlaHsd * BALB/cJ)
decreased susceptibility to prion infection J:92302
Prnptm2(PRNP*129M)Tkit/Prnptm2(PRNP*129M)Tkit
(Not Specified)
decreased susceptibility to prion infection J:126777, J:105882
increased susceptibility to prion infection J:126777, J:105882
Prnptm2(PRNP*129M)Tkit/Prnptm2(PRNP*129M)Tkit
Tg(Prnp-PRNP*129M)1Tkit/?

(Not Specified)
decreased susceptibility to prion infection J:126777
increased susceptibility to prion infection J:126777
Prnptm2(PRNP*129M)Tkit/Prnptm3(PRNP*129V)Tkit
(Not Specified)
decreased susceptibility to prion infection J:105882
Prnptm2Lnq/Prnptm2Lnq
(involves: 129P2/OlaHsd * C57BL/6N)
immune system phenotype J:154937
Prnptm2Tuzi/Prnp+
(involves: 129P2/OlaHsd)
immune system phenotype J:92302
Prnptm2Tuzi/Prnp+
Tg(CMV-cre)1Cgn/?

(involves: 129P2/OlaHsd * BALB/cJ)
decreased susceptibility to prion infection J:92302
Prnptm2Tuzi/Prnptm2Edin
(involves: 129P2/OlaHsd)
decreased susceptibility to prion infection J:92302
Prnptm2Tuzi/Prnptm2Edin
Tg(CMV-cre)1Cgn/?

(involves: 129P2/OlaHsd * BALB/cJ)
decreased susceptibility to prion infection J:92302
Prnptm3(PRNP*129V)Tkit/Prnptm3(PRNP*129V)Tkit
(Not Specified)
abnormal spleen morphology J:126777
decreased susceptibility to prion infection J:126777, J:105882
increased susceptibility to prion infection J:126777
Prnptm3(PRNP*129V)Tkit/Prnptm3(PRNP*129V)Tkit
Tg(Prnp-PRNP*129V)139Tkit/?

(Not Specified)
abnormal susceptibility to infection J:126777
decreased susceptibility to prion infection J:105882
Prnptm3(PRNP*129V)Tkit/Prnptm3(PRNP*129V)Tkit
Tg(Prnp-PRNP*129V)144Tkit/?

(Not Specified)
decreased susceptibility to prion infection J:105882
Prnptm4(PRNP)Tkit/Prnptm4(PRNP)Tkit
(Not Specified)
increased susceptibility to prion infection J:105882
Prnptm4(PRNP)Tkit/Prnptm4(PRNP)Tkit
Tg(Prnp-PRNP)32Tkit/?

(Not Specified)
increased susceptibility to prion infection J:105882
Prnptm5(PRNP*)TKit/Prnptm5(PRNP*)TKit
(Not Specified)
immune system phenotype J:126777
Prnptm5(PRNP*)TKit/Prnptm5(PRNP*)TKit
Tg(Prnp-PRNP*)1Tkit/?

(Not Specified)
decreased susceptibility to prion infection J:126777
increased susceptibility to prion infection J:126777
Prnr1RIII/FaDk/Prnr1RIII/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:89558
Prnr2C57BL/FaDk/Prnr2C57BL/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:89558
Prnr2C57BL/FaDk/Prnr2RIII/FaDk
(involves: C57BL/FaDk * RIII/FaDk)
decreased susceptibility to prion infection J:89558
Proctm1Fjc/Proctm1Fjc
(involves: 129S1/Sv * 129X1/SvJ * Swiss)
abnormal innate immunity J:50527
liver inflammation J:50527
Procrtm1.1Pcl/Procrtm1.1Pcl
(involves: 129S2/SvPas * C57BL/6)
bone marrow failure J:225914
enlarged spleen J:225914
increased circulating interleukin-6 level J:225914
increased spleen red pulp amount J:225914
increased spleen weight J:225914
increased splenocyte number J:225914
increased susceptibility to endotoxin shock J:225914
Proser2em1(IMPC)Ccpcz/Proser2em1(IMPC)Ccpcz
(C57BL/6NCrl-Proser2em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Prox1tm1Gco/Prox1+
(involves: 129S1/Sv * 129X1/SvJ * NMRI)
abnormal lymph circulation J:102652, J:57646
abnormal lymphatic vessel morphology J:102652
increased inflammatory response J:102652
increased macrophage cell number J:102652
Prox1tm1Gco/Prox1+
(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymph circulation J:57646
Prox1tm1Gco/Prox1tm1Gco
(involves: 129S1/Sv * 129X1/SvJ * NMRI)
abnormal lymph organ development J:57646
Prox1tm1Gco/Prox1tm2Gco
Tg(Tek-cre)1Ywa/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
absent lymphatic vessels J:125507
Prox1tm1Gco/Prox1tm5(GFP/cre)Gco
(involves: 129S1/Sv * 129X1/SvJ * NMRI)
decreased lymphatic vessel endothelial cell number J:158959
Prox1tm2Gco/Prox1+
Tg(Tek-cre)1Ywa/0

(involves: 129S1/Sv * C57BL/6 * NMRI * SJL)
abnormal lymph circulation J:102652
abnormal lymphatic vessel morphology J:102652
Prox1tm4.1Gco/Prox1tm4.1Gco
(involves: 129S1/Sv * C57BL/10 * CBA/Ca)
decreased lymphatic vessel endothelial cell number J:158959
Prpf3tm1b(KOMP)Wtsi/Prpf3+
(C57BL/6N-Prpf3tm1b(KOMP)Wtsi/Bay)
increased neutrophil cell number J:211773
Prph2em1Sal/Prph2+
(C57BL/6J-Prph2em1Sal)
eye inflammation J:342243
Prph2em1Sal/Prph2em1Sal
(C57BL/6J-Prph2em1Sal)
eye inflammation J:342243
increased microglial cell activation J:342243
Prph2Rd2/Prph2Rd2
(O20/A-Prph2Rd2)
abnormal macrophage morphology J:6432
Prps2tm1a(KOMP)Wtsi/Y
(involves: C57BL/6N)
abnormal B cell physiology J:214383
Prps2tm1a(KOMP)Wtsi/Y
Tg(IghMyc)22Bri/0

(involves: C57BL/6N * SJL)
abnormal B cell physiology J:214383
increased B cell apoptosis J:214383
Prr7tm1(KOMP)Vlcg/Prr7tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
decreased CD4-positive, alpha-beta T cell number J:237776
immune system phenotype J:237776
Prrg4em1(IMPC)Mbp/Prrg4em1(IMPC)Mbp
(C57BL/6NCrl-Prrg4em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Prss3btm1.1Satom/Prss3b+
(B6(FVB)-Prss3btm1.1Satom)
acute pancreas inflammation J:267764
chronic pancreas inflammation J:267764
Prss8tm1.1Hum/Prss8tm1.2Hum
Tg(KRT14-cre)1Ipc/0

(involves: 129/Sv * C57BL/6 * FVB/N * SJL)
thymus medulla hypoplasia J:100139
Prss12em1(IMPC)Ccpcz/Prss12em1(IMPC)Ccpcz
(C57BL/6N-Prss12em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Prss16tm1.1Mal/Prss16+
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6)
abnormal positive T cell selection J:148034
decreased CD4-positive, alpha-beta T cell number J:148034
decreased single-positive T cell number J:148034
lymph node hypoplasia J:148034
Prss16tm1.1Mal/Prss16tm1.1Mal
(involves: 129S2/SvPas * C57BL/6)
abnormal professional antigen presenting cell morphology J:148034
abnormal thymus cortex morphology J:148034
Prss16tm1.1Mal/Prss16tm1.1Mal
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)1Pas/?

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6)
abnormal positive T cell selection J:148034
decreased CD4-positive, alpha-beta T cell number J:148034
decreased double-positive T cell number J:148034
decreased single-positive T cell number J:148034
lymph node hypoplasia J:148034
spleen hypoplasia J:148034
thymus hypoplasia J:148034
Prss16tm1Cbo/Prss16tm1Cbo
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:94751
Prss21em1(IMPC)Ccpcz/Prss21+
(C57BL/6N-Prss21em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Prss27tm1.1(NCOM)Mfgc/Prss27tm1.1(NCOM)Mfgc
(C57BL/6N-Prss27tm1.1(NCOM)Mfgc/Tcp)
decreased monocyte cell number J:211773
Prss33em1(IMPC)Ccpcz/Prss33em1(IMPC)Ccpcz
(C57BL/6N-Prss33em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
small spleen J:211773
Prss34tm1.1Hkar/Prss34tm1.1Hkar
(involves: C57BL/6)
decreased inflammatory response J:238924
immune system phenotype J:238924
Prss35em1(IMPC)Ccpcz/Prss35em1(IMPC)Ccpcz
(C57BL/6N-Prss35em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Prss47em1(IMPC)Ccpcz/Prss47em1(IMPC)Ccpcz
(C57BL/6N-Prss47em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Prss48em1(IMPC)Ccpcz/Prss48em1(IMPC)Ccpcz
(C57BL/6NCrl-Prss48em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Prss50tm1a(EUCOMM)Hmgu/Prss50tm1a(EUCOMM)Hmgu
(C57BL/6N-Prss50tm1a(EUCOMM)Hmgu/H)
decreased CD8-positive, alpha-beta T cell number J:165965
decreased T cell number J:165965
Prss53em3(IMPC)Wtsi/Prss53em3(IMPC)Wtsi
(C57BL/6N-Prss53em3(IMPC)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Prss54em1(IMPC)Ccpcz/Prss54em1(IMPC)Ccpcz
(C57BL/6N-Prss54em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Prss55em1(IMPC)Ccpcz/Prss55em1(IMPC)Ccpcz
(C57BL/6NCrl-Prss55em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Prss56em1(IMPC)J/Prss56em1(IMPC)J
(C57BL/6NJ-Prss56em1(IMPC)J/J)
decreased leukocyte cell number J:211773
Prss57em1(IMPC)Ccpcz/Prss57em1(IMPC)Ccpcz
(C57BL/6N-Prss57em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
decreased NK T cell number J:211773
enlarged thymus J:211773
Prss57tm1.1Gne/Prss57tm1.1Gne
(C57BL/6N-Prss57tm1.1Gne)
abnormal mast cell morphology J:301479
abnormal mast cell physiology J:301479
decreased mast cell histamine storage J:301479
Prss57tm1Lex/Prss57tm1Lex
(involves: 129S5/SvEvBrd)
abnormal mast cell physiology J:301479
Prtn3tm1.1Hrlu/Prtn3tm1.1Hrlu
(involves: C57BL/6)
abnormal neutrophil physiology J:217636
increased neutrophil cell number J:217636
Prxl2atm1(KOMP)Vlcg/Prxl2atm1(KOMP)Vlcg
(C57BL/6N-Prxl2atm1(KOMP)Vlcg)
white adipose tissue inflammation J:234040
Psaptm1Ggb/Psaptm1Ggb
(involves: 129S/SvEv * C57BL/6J)
abnormal microglial cell physiology J:121761
abnormal spleen morphology J:121761
Psaptm1Juma/Psaptm1Juma
(FVB.129S-Psaptm1Juma)
abnormal microglial cell physiology J:121761
Psaptm1Suz/Psaptm1Suz
(involves: 129P2/OlaHsd)
abnormal macrophage morphology J:113052
decreased spleen weight J:106511
Psaptm2Ggb/Psaptm2Ggb
(involves: 129S/SvEv * C57BL/6J)
CNS inflammation J:137650
kidney inflammation J:137650
microgliosis J:198242
Psaptm2Suz/Psaptm2Suz
(involves: 129S/SvEv * C57BL/6J)
abnormal macrophage morphology J:78223
CNS inflammation J:78223
microgliosis J:198242
Psaptm4.1Ggb/Psaptm4.1Ggb
(involves: 129S/SvEv * C57BL/6J)
microgliosis J:198242
Pscatm1b(EUCOMM)Hmgu/Pscatm1b(EUCOMM)Hmgu
(C57BL/6N-Pscatm1b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
Pscr1DBA/2/Pscr1DBA/2
(involves: BALB/c * DBA/2)
decreased susceptibility to bacterial infection J:8914
Pscr1DBA/2/Pscr1DBA/2
Pscr2DBA/2/Pscr2DBA/2
Pscr3DBA/2/Pscr3DBA/2

(involves: C57BL/6 * DBA/2)
decreased susceptibility to bacterial infection J:8914
Pscr2DBA/2/Pscr2DBA/2
(involves: BALB/c * DBA/2)
decreased susceptibility to bacterial infection J:8914
Pscr3DBA/2/Pscr3DBA/2
(involves: BALB/c * DBA/2)
decreased susceptibility to bacterial infection J:8914
Psdem1(IMPC)Mbp/Psdem1(IMPC)Mbp
(C57BL/6NCrl-Psdem1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Psen1tm1.1Ruvi/Psen1tm1.1Ruvi
Tg(APP)8.9Btla/0

(involves: 129S2/SvPas * C57BL/6J)
microgliosis J:187475
Psen1tm1Bdes/Psen1+
Psen2tm1Bdes/Psen2tm1Bdes

(involves: 129P2/OlaHsd)
abnormal T cell subpopulation ratio J:91235
arteritis J:91235
autoimmune response J:91235
chronic inflammation J:91235
dermatitis J:91235
enlarged lymph nodes J:91235
enlarged spleen J:91235
glomerulonephritis J:91235
increased anti-single stranded DNA antibody level J:91235
increased immunoglobulin level J:91235
increased incidence of corneal inflammation J:91235
increased inflammatory response J:91235
increased leukocyte cell number J:91235
increased susceptibility to autoimmune disorder J:91235
kidney inflammation J:91235
skin inflammation J:91235
Psen1tm2Shn/Psen1tm4.1Shn
Psen2tm1Haa/Psen2tm1Haa
Tg(Camk2a-cre)1Shn/0

(involves: 129 * 129S4/SvJae * C57BL/6 * C57BL/6J * CBA)
microgliosis J:219929
Psen2em1(IMPC)Ccpcz/Psen2em1(IMPC)Ccpcz
(C57BL/6NCrl-Psen2em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Psip1Gt(betageo)1Hgs/Psip1Gt(betageo)1Hgs
(B6.129P2-Psip1Gt(betageo)1Hgs)
blepharitis J:112975
spleen atrophy J:112975
Psip1Gt(betageo)1Hgs/Psip1Gt(betageo)1Hgs
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * MF1))
blepharitis J:112975
spleen atrophy J:112975
Psma8em1(IMPC)Tcp/Psma8em1(IMPC)Tcp
(C57BL/6N-Psma8em1(IMPC)Tcp/Tcp)
increased monocyte cell number J:211773
small thymus J:211773
Psmb8tm1Hjf/Psmb8tm1Hjf
(either: 129P2/OlaHsd or (involves: 129P2/OlaHsd * C57BL/6))
decreased level of surface class I molecules J:20012
defective intracellular transport of class I molecules J:20012
Psmb8tm1Hjf/Psmb8tm1Hjf
(involves: 129P2/OlaHsd)
abnormal dendritic cell antigen presentation J:180765
decreased level of surface class I molecules J:180765
Psmb8tm1Hjf/Psmb8tm1Hjf
Tg(TcraTcrb)1100Mjb/?

(involves: 129P2/OlaHsd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:107657
Psmb9tm1Stl/Psmb9tm1Stl
(involves: 129P2/OlaHsd * C57BL/6)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:21549
abnormal immune system physiology J:21549
decreased CD8-positive, alpha-beta T cell number J:21549
increased susceptibility to Orthomyxoviridae infection J:21549
Psmb10tm1Mgro/Psmb10tm1Mgro
(involves: 129S2/SvPas * C57BL/6)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:125058
abnormal cytotoxic T cell physiology J:125058
decreased CD8-positive, alpha-beta T cell number J:125058
decreased T cell proliferation J:125058
Psmb10tm1Mgro/Psmb10tm1Mgro
Psmb9/Psmb8tm1Klr/Psmb9/Psmb8tm1Klr

(B6.129-Psmb10tm1Mgro Psmb9/Psmb8tm1Klr)
abnormal antigen presentation via MHC class I J:180765
abnormal B lymphocyte antigen presentation J:180765
abnormal dendritic cell antigen presentation J:180765
decreased CD8-positive, alpha-beta T cell number J:180765
decreased level of surface class I molecules J:180765
Psmb10tm1Mgro/Psmb10tm1Mgro
Psmb9/Psmb8tm1Klr/Psmb9/Psmb8tm1Klr

(B6.129-Psmb10tm1Mgro Psmb9/Psmb8tm1Klr)
abnormal antigen presentation via MHC class I J:180765
abnormal B lymphocyte antigen presentation J:180765
abnormal dendritic cell antigen presentation J:180765
decreased CD8-positive, alpha-beta T cell number J:180765
decreased level of surface class I molecules J:180765
Psmb10tm1Mgro/Psmb10Tub6
(involves: 129S2/SvPas * C3HeB/FeJ)
decreased NK cell number J:261081
decreased T cell number J:261081
increased granulocyte number J:261081
Psmb10Tub6/Psmb10+
(C3HeB/FeJ-Psmb10Tub6)
abnormal T cell activation J:261081
decreased CD4-positive, alpha-beta T cell number J:261081
decreased CD8-positive, alpha-beta T cell number J:261081
decreased interferon-gamma secretion J:261081
decreased T cell number J:261081
increased susceptibility to bacterial infection induced morbidity/mortality J:261081
Psmb10Tub6/Psmb10Tub6
(C3HeB/FeJ-Psmb10Tub6)
absent lymph nodes J:261081
absent spleen white pulp J:261081
athymia J:261081
decreased B cell number J:261081
decreased immunoglobulin level J:261081
decreased leukocyte cell number J:261081
decreased NK cell number J:261081
decreased spleen red pulp amount J:261081
decreased T cell number J:261081
increased circulating interleukin-1 level J:261081
increased circulating interleukin-6 level J:261081
increased circulating tumor necrosis factor level J:261081
increased granulocyte number J:261081
increased inflammatory response J:261081
skin inflammation J:261081
Psmb10Tub6/Psmb10Tub6
(B6.C3Fe-Psmb10Tub6)
increased granulocyte number J:261081
Psmb10Tub6/Psmb10Tub6
(C.C3Fe-Psmb10Tub6)
increased granulocyte number J:261081
Psmb11em1(IMPC)Ccpcz/Psmb11em1(IMPC)Ccpcz
(C57BL/6NCrl-Psmb11em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
decreased effector memory T-helper cell number J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased CD4-positive NK T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased memory-marker CD4-positive NK T cell number J:211773
increased NK T cell number J:211773
increased T-helper cell number J:211773
Psmb11tm1(Psmb8)Khog/Psmb11+
(involves: C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:196156
Psmb11tm1(Psmb8)Khog/Psmb11tm1(Psmb8)Khog
(involves: C57BL/6)
abnormal CD8-positive, alpha beta T cell morphology J:196156
abnormal self tolerance J:196156
abnormal T cell differentiation J:196156
abnormal T cell receptor V(D)J recombination J:196156
decreased CD8-positive, alpha-beta T cell number J:196156
decreased memory T cell number J:196156
increased T cell proliferation J:196156
Psmb11tm1(Psmb8)Khog/Psmb11tm1(Psmb8)Khog
Psmb8tm1Hjf/Psmb8tm1Hjf

(involves: 129P2/OlaHsd * C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:196156
Psmb11tm1.1(Psmb8)Khog/Psmb11tm1.1(Psmb8)Khog
Psmb8tm1Hjf/Psmb8tm1Hjf

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NTac)
abnormal T cell receptor V(D)J recombination J:196156
decreased CD8-positive, alpha-beta T cell number J:196156
Psmb11tm1Smta/Psmb11tm1Smta
(involves: C57BL/6 * CBA)
decreased CD8-positive, alpha-beta T cell number J:121869
Psmc4tm1.1Ryot/Psmc4tm1.2Ryot
Tg(SLC18A3-cre)KMisa/0

(involves: C57BL/6 * C57BL/6N)
microgliosis J:193770
Psme2tm1Yya/Psme2tm1Yya
(involves: 129P2/OlaHsd)
abnormal CD8-positive, alpha-beta T cell physiology J:58875
decreased cytotoxic T cell cytolysis J:58875
defective assembly of class I molecules J:58875
Psme3tm1Jjm/Psme3tm1Jjm
(B6.129X1-Psme3tm1Jjm)
decreased double-positive T cell number J:88626
increased susceptibility to fungal infection J:88626
Psme4b2b1508Clo/Psme4b2b1508Clo
(C57BL/6J-Psme4b2b1508Clo)
thymus hypoplasia J:175213
Psmf1tm1c(EUCOMM)Hmgu/Psmf1tm1c(EUCOMM)Hmgu
Tg(Pcp2-cre)GN135Gsat/0

(involves: C57BL/6J * C57BL/6N * FVB/N)
microgliosis J:282431
Pspc1em1(IMPC)Mbp/Pspc1em1(IMPC)Mbp
(C57BL/6N-Pspc1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Psphtm1a(EUCOMM)Hmgu/Psphtm1a(EUCOMM)Hmgu
(C57BL/6N-Psphtm1a(EUCOMM)Hmgu/Wtsi)
abnormal thymus morphology J:239583
abnormal thymus topology J:239583
absent connection between subcutaneous lymph vessels and lymph sac J:239583
athymia J:239583
blood in lymph vessels J:239583
spleen hypoplasia J:239583
Pstpip1em1(IMPC)Ccpcz/Pstpip1em1(IMPC)Ccpcz
(C57BL/6N-Pstpip1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased T-helper cell number J:211773
Pstpip1tm1.1Dtg/Pstpip1tm1.1Dtg
(involves: BALB/cJ * C57BL/6)
immune system phenotype J:196002
Pstpip1tm1Spg/Pstpip1tm1Spg
(involves: 129S/SvEv * C57BL/6)
abnormal immune system cell morphology J:101977
abnormal T cell physiology J:101977
Pstpip2cmo/Pstpip2cmo
(C.D2-Qa2)
chronic inflammation J:1534
Pstpip2cmo/Pstpip2cmo
(C.Cg-Pstpip2cmo/J)
abnormal lymph node morphology J:104476
ear inflammation J:104476
enlarged spleen J:104476
osteomyelitis J:104476, J:105410
Pstpip2em1(IMPC)Tcp/Pstpip2em1(IMPC)Tcp
(C57BL/6NCrl-Pstpip2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Pstpip2Lupo/Pstpip2Lupo
(either: (involves: C3HeB/FeJ) or (involves: C3HeB/FeJ * C57BL/6J))
abnormal cytokine secretion J:125785
increased autoantibody level J:125785
increased IgE level J:125785
increased IgG1 level J:125785
increased IgG2a level J:125785
increased IgG level J:125785
skin inflammation J:125785
Pstpip2Lupo/Pstpip2Lupo
Rag1tm1Mom/Rag1tm1Mom

(involves: 129S7/SvEvBrd * C3HeB/FeJ * C57BL/6J)
skin inflammation J:125785
Pstpip2m1Bcs/Pstpip2m1Bcs
(involves: C57BL/6)
abnormal inflammatory response J:196534
abnormal microglial cell morphology J:196534
autoimmune response J:196534
ear inflammation J:196534
skin inflammation J:196534
pta/pta
(C57BL/6J-pta)
thymus hypoplasia J:94456
Ptafrtm1Tksh/Ptafrtm1Tksh
(involves: 129P2/OlaHsd * C57BL/6)
decreased inflammatory response J:87866
increased susceptibility to parasitic infection J:87866
increased susceptibility to type I hypersensitivity reaction J:88505
Ptafrtm1Tksh/Ptafrtm1Tksh
(C57BL/6-Ptafrtm1Tksh)
decreased susceptibility to bacterial infection J:88589
Ptch1tm1Bjw/Ptch1tm1Bjw
Tg(KRT14-cre)8Brn/0

(involves: 129T2/SvEms * FVB/N)
thymus hypoplasia J:231264
Ptch1tm1Hahn/Ptch1tm1Hahn
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal double-negative T cell morphology J:127207
abnormal thymus lobule morphology J:127207
decreased B cell number J:127207
decreased double-positive T cell number J:127207
decreased immature B cell number J:127207
decreased lymphocyte cell number J:127207
decreased pre-B cell number J:127207
decreased transitional stage B cell number J:127207
increased B cell number J:127207
increased double-negative T cell number J:127207
increased mature B cell number J:127207
increased neutrophil cell number J:127207
increased single-positive T cell number J:127207
thymus hypoplasia J:127207
Ptch2tm1Dgen/Ptch2tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:101679
increased neutrophil cell number J:101679
Ptch2tm3b(EUCOMM)Hmgu/Ptch2tm3b(EUCOMM)Hmgu
(C57BL/6N-Ptch2tm3b(EUCOMM)Hmgu/Bay)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Ptchd1tm1b(KOMP)IcsOrl/Y
(C57BL/6N-Ptchd1tm1b(KOMP)IcsOrl/Ics)
abnormal spleen morphology J:211773
Ptcratm1(icre)Hjf/Ptcratm1(icre)Hjf
(B6.129P2-Ptcratm1(icre)Hjf)
decreased DN4 thymocyte number J:197923
decreased double-positive T cell number J:197923
decreased thymocyte number J:197923
Ptcratm1.1Shoy/Ptcratm1.1Shoy
(involves: C57BL/6)
decreased double-positive T cell number J:166147
decreased T cell number J:166147
decreased thymocyte number J:166147
increased DN3 thymocyte number J:166147
increased gamma-delta T cell number J:166147
increased T cell number J:166147
Ptcratm1Bjf/Ptcra+
(involves: 129X1/SvJ)
abnormal T cell differentiation J:94338
decreased double-negative T cell number J:94338
decreased single-positive T cell number J:94338
Ptcratm1Vbo/Ptcratm1Vbo
(involves: 129P2/OlaHsd * C57BL/6)
arrested T cell differentiation J:91542
increased double-negative T cell number J:91542
Ptcratm1Vbo/Ptcratm1Vbo
(involves: 129P2/OlaHsd)
abnormal double-positive T cell morphology J:123569
decreased DN4 thymocyte number J:123569
increased DN3 thymocyte number J:123569
thymus hypoplasia J:123569
Ptdss1tm1b(EUCOMM)Hmgu/Ptdss1tm1b(EUCOMM)Hmgu
(C57BL/6N-Ptdss1tm1b(EUCOMM)Hmgu/Ics)
decreased large unstained cell number J:211773
Ptentm1.1Hwu/Pten+
(involves: 129S4/SvJae * BALB/c)
lymphoid hyperplasia J:110567
Ptentm1Engc/Ptentm1Engc
(involves: CD-1)
abnormal microglial cell physiology J:210487
Ptentm1Hwu/Ptentm1Hwu
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJae)
abnormal alveolar macrophage morphology J:148947
abnormal cytokine level J:148947
abnormal macrophage chemotaxis J:148947
abnormal neutrophil physiology J:148947, J:114699, J:145331
decreased susceptibility to bacterial infection J:148947
decreased susceptibility to bacterial infection induced morbidity/mortality J:148947
impaired neutrophil recruitment J:148947
increased susceptibility to bacterial infection J:148947
increased susceptibility to bacterial infection induced morbidity/mortality J:148947
lung inflammation J:148947
Ptentm1Hwu/Ptentm1Hwu
Rps6kb1tm1Gtho/Rps6kb1tm1Gtho
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA)
enlarged spleen J:169097
enlarged thymus J:169097
Ptentm1Hwu/Ptentm1Hwu
Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/0
Tg(TPO-cre)1Shk/0

(involves: 129S4/SvJae * FVB/NCr * FVB/NJ)
abnormal thymus physiology J:177181
Ptentm1Hwu/Ptentm1Hwu
Tg(CD2-icre)4Kio/0

(involves: 129S4/SvJae * C57BL/6 * C57BL/10 * CBA/Ca)
enlarged thymus J:216983
Ptentm1Hwu/Ptentm1Hwu
Tg(Cdh5-cre)7Mlia/0

(involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N)
enlarged lymph nodes J:135172
enlarged spleen J:135172
enlarged thymus J:135172
increased leukocyte cell number J:135172
increased neutrophil cell number J:135172
Ptentm1Hwu/Ptentm1Hwu
Tg(Fabp4-cre)1Abel/0

(involves: 129S4/SvJae)
abnormal cytokine level J:97588
Ptentm1Hwu/Ptentm1Hwu
Tg(GZMB-cre)1Jcb/0

(involves: 129S4/SvJae * FVB/N)
abnormal CD8-positive, alpha-beta T cell physiology J:164425
decreased interleukin-2 secretion J:164425
Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
enlarged spleen J:169097
enlarged thymus J:169097
Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0

(BKS.Cg-Ptprcb Thy1a Tg(Mx1-cre)1Cgn Ptentm1Hwu)
enlarged thymus J:109085
spleen hyperplasia J:109085
Ptentm1Hwu/Ptentm1Hwu
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Tg(Mx1-cre)1Cgn Ptentm1Hwu)
decreased B cell number J:232645
decreased lymphocyte cell number J:232645
decreased T cell number J:232645
enlarged spleen J:232645
increased granulocyte number J:232645
increased macrophage cell number J:232645
increased monocyte cell number J:232645
increased spleen weight J:232645
Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0

(involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2)
prostate gland inflammation J:93902
pyelonephritis J:124208
Ptentm1Mak/Pten+
(involves: 129P2/OlaHsd * C57BL/6J)
enlarged Peyer's patches J:63478
Ptentm1Rps/Pten+
(involves: 129S1/Sv * C57BL/6J)
abnormal lymph node B cell domain morphology J:53065
enlarged spleen J:53065
enlarged thymus J:53065
lymph node hyperplasia J:53065
Ptentm2.1Ppp/Ptentm2.1Ppp
Tnfrsf4tm2(cre)Nik/Tnfrsf4+

(involves: 129S1/Sv * 129X1/SvJ)
increased germinal center B cell number J:164283
increased IgG1 level J:164283
increased T follicular helper cell number J:164283
Ptentm2Mak/Ptentm2Mak
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129P2/OlaHsd * C57BL/6 * DBA)
liver inflammation J:138099
Ptf1atm1Pkwe/Ptf1atm1Pkwe
(involves: 129P2/OlaHsd * C57BL/6)
abnormal spleen morphology J:51571
Ptgdr2tm1Byl/Ptgdr2tm1Byl
(involves: C57BL/6J)
abnormal cytokine secretion J:107519
increased eosinophil cell number J:107519
Ptgdr2tm1Tasa/Ptgdr2tm1Tasa
(involves: 129/Sv * BALB/c)
impaired eosinophil recruitment J:130892
Ptgdr2tm1Tasa/Ptgdr2tm1Tasa
(C.129-Ptgdr2tm1Tasa)
abnormal chemokine level J:131146
abnormal inflammatory response J:131146
decreased IgE level J:131146
decreased inflammatory response J:131146
decreased susceptibility to type IV hypersensitivity reaction J:131146
Ptgdr2tm1Tasa/Ptgdr2tm1Tasa
(B6.129-Ptgdr2tm1Tasa)
increased susceptibility to type I hypersensitivity reaction J:197334
Ptgdrtm1Sna/Ptgdrtm1Sna
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage activation involved in immune response J:243958
brain inflammation J:243958
decreased microglial cell activation J:243958
increased CD4-positive, alpha-beta T cell number J:243958
increased interleukin-1 beta secretion J:243958
increased regulatory T cell number J:243958
increased susceptibility to Coronaviridae infection J:243958
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:243958
respiratory system inflammation J:61023
Ptgdrtm1Sna/Ptgdrtm1Sna
(B6.129P2-Ptgdrtm1Sna/Sna)
abnormal dermal mast cell morphology J:197334
abnormal mast cell physiology J:197334
decreased mast cell degranulation J:197334
decreased mast cell histamine storage J:197334
decreased susceptibility to type I hypersensitivity reaction J:197334
Ptgdstm1Mfg/Ptgdstm1Mfg
(involves: C57BL/6)
immune system phenotype J:98963
Ptgdstm1Ohy/Ptgdstm1Ohy
(B6.129P2-Ptgdstm1Ohy)
abnormal dermal mast cell morphology J:197334
decreased mast cell degranulation J:197334
decreased mast cell histamine storage J:197334
decreased susceptibility to type I hypersensitivity reaction J:197334
immune system phenotype J:197334
Ptger1tm1Jdm/Ptger1tm1Jdm
(DBA/1LacJ-Ptger1tm1Jdm)
immune system phenotype J:72198, J:78964
Ptger1tm1Sna/Ptger1tm1Sna
(B6CrSlc.129P2-Ptger1tm1Sna/Sna)
abnormal CD8-positive, alpha-beta T cell differentiation J:128435
abnormal cervical lymph node morphology J:128435
abnormal interferon-gamma secretion J:128435
abnormal lymph node morphology J:128435
abnormal response to infection J:82750
abnormal T-helper 1 cell differentiation J:128435
decreased susceptibility to type IV hypersensitivity reaction J:128435
immune system phenotype J:128435, J:197334
Ptger2tm1.1Kand/Ptger2tm1.1Kand
Tg(ITGAM-cre)2781Gkl/0

(involves: C57BL/6 * CBA)
abnormal microglial cell physiology J:202677
decreased susceptibility to endotoxin shock J:202677
Ptger2tm1Brey/Ptger2tm1Brey
(involves: 129S6/SvEvTac * C57BL/6)
abnormal response to infection J:120725
Ptger2tm1Brey/Ptger2tm1Brey
(C.129S6-Ptger2tm1Brey)
abnormal microglial cell physiology J:97062
Ptger2tm1Brey/Ptger2tm1Brey
(involves: 129S6/SvEvTac * BALB/c)
abnormal response to infection J:164638
Ptger2tm1Rsz/Ptger2tm1Rsz
(involves: 129S6/SvEvTac * C57BL/6)
abnormal osteoclast differentiation J:77408
Ptger2tm1Sna/Ptger2tm1Sna
(B6.129P2-Ptger2tm1Sna/Sna)
immune system phenotype J:197334
Ptger2tm2Bhk/Ptger2tm2Bhk
(involves: 129P2/OlaHsd * 129S/SvEv)
immune system phenotype J:78964
Ptger3tm1Cof/Ptger3tm1Cof
(involves: 129P2/OlaHsd * 129S/SvEv)
immune system phenotype J:78964
Ptger3tm1Sna/Ptger3tm1Sna
(B6.129P2-Ptger3tm1Sna/Sna)
abnormal response to infection J:82750
increased susceptibility to type I hypersensitivity reaction J:197334
Ptger4tm1.1Matb/Ptger4tm1.1Matb
Tg(Myh6-cre)2182Mds/0

(involves: 129S6/SvEvTac * FVB/N)
heart inflammation J:158439
Ptger4tm1Bhk/Ptger4tm1Bhk
(involves: 129P2/OlaHsd * 129S/SvEv)
lymphangiectasis J:44108
Ptger4tm1Bhk/Ptger4tm1Bhk
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal circulating interleukin-6 level J:78964
abnormal circulating serum amyloid protein level J:78964
abnormal cytokine level J:78964
abnormal macrophage physiology J:78964
decreased susceptibility to induced arthritis J:78964
immune system phenotype J:78964
rheumatoid arthritis J:78964
Ptger4tm1Sna/Ptger4tm1Sna
(involves: 129P2/OlaHsd * C57BL/6)
abnormal Langerhans cell physiology J:83725
abnormal osteoclast differentiation J:63070
abnormal osteoclast physiology J:63070
abnormal T cell activation J:83725
decreased interferon-gamma secretion J:83725
decreased susceptibility to type IV hypersensitivity reaction J:83725
decreased T cell proliferation J:83725
immune system phenotype J:83725, J:197334
Ptges2tm1Kymm/Ptges2tm1Kymm
(B6.Cg-Ptges2tm1Kymm)
increased susceptibility to type I hypersensitivity reaction J:197334
Ptgestm1.1Gaf/Ptgestm1.1Gaf
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * C57BL/6)
abnormal leukocyte physiology J:210141
increased leukocyte cell number J:210141
Ptgestm1Aki/Ptgestm1Aki
(involves: 129X1/SvJ * C57BL/6)
abnormal inflammatory response J:91821
chronic inflammation J:91821
impaired macrophage chemotaxis J:91821
Ptgestm1Aki/Ptgestm1Aki
(B6.129P2-Ptgestm1Aki)
increased susceptibility to type I hypersensitivity reaction J:197334
Ptgestm1Lpa/Ptgestm1Lpa
(DBA/1LacJ-Ptgestm1Lpa)
decreased inflammatory response J:89960, J:90980
Ptgfrtm1Sna/Ptgfrtm1Sna
(B6.129P2-Ptgfrtm1Sna)
immune system phenotype J:197334
Ptgirtm1Sna/Ptgirtm1Sna
(involves: 129P2/OlaHsd * C57BL/6)
decreased acute inflammation J:42275
Ptgirtm1Sna/Ptgirtm1Sna
(B6.129P2-Ptgirtm1Sna/Sna)
immune system phenotype J:197334
Ptgisem1(IMPC)Mbp/Ptgisem1(IMPC)Mbp
(C57BL/6N-Ptgisem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Ptgs1tm1Fun/Ptgs1tm1Fun
(involves: 129S6/SvEvTac * C57BL/6)
decreased inflammatory response J:97351
Ptgs1tm1Unc/Ptgs1tm1Unc
(involves: 129P2/OlaHsd * C57BL/6)
decreased inflammatory response J:29511
enlarged spleen J:60668
increased susceptibility to endotoxin shock J:75611
increased susceptibility to induced colitis J:158426, J:60668
Ptgs1tm1Unc/Ptgs1tm1Unc
(B6.129P2-Ptgs1tm1Unc)
decreased susceptibility to induced arthritis J:110716
Ptgs2tm1.1Fun/Ptgs2tm1.1Fun
(involves: 129S6/SvEvTac)
kidney inflammation J:148699
Ptgs2tm1.1Wls/Ptgs2tm1.1Wls
(B6.129-Ptgs2tm1.1Wls)
increased susceptibility to endotoxin shock J:156331
Ptgs2tm1Jed/Ptgs2tm1Jed
(involves: 129S7/SvEvBrd)
immune system phenotype J:29974
pyelonephritis J:29974
Ptgs2tm1Jed/Ptgs2tm1Jed
(involves: 129S7/SvEvBrd * C57BL/6)
peritoneal inflammation J:118171
Ptgs2tm1Jed/Ptgs2tm1Jed
(involves: 129S7/SvEvBrd * CD-1)
abnormal response to infection J:120725
Ptgs2tm1Unc/Ptgs2+
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:124756
Ptgs2tm1Unc/Ptgs2tm1Unc
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal macrophage physiology J:29510
abnormal mesenteric lymph node morphology J:29510
immune system phenotype J:29510
peritoneal inflammation J:29510
spleen hyperplasia J:29510
tubulointerstitial nephritis J:29510
Ptgs2tm1Unc/Ptgs2tm1Unc
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:124756
Ptgs2tm1Unc/Ptgs2tm1Unc
(involves: 129P2/OlaHsd * C57BL/6)
decreased susceptibility to endotoxin shock J:75611
enlarged spleen J:60668
increased leukocyte cell number J:60668
increased susceptibility to induced colitis J:158426, J:60668
increased tumor necrosis factor secretion J:108054
peritoneal inflammation J:60668
Ptgs2tm1Unc/Ptgs2tm1Unc
(B6.129P2-Ptgs2tm1Unc)
abnormal class switch recombination J:140698
abnormal memory B cell differentiation J:140698
abnormal response to infection J:140698
decreased IgG1 level J:140698
decreased IgG2a level J:140698
decreased IgG3 level J:140698
decreased susceptibility to induced arthritis J:110716
increased IgM level J:140698
Ptgs2tm1Unc/Ptgs2tm2.1Hahe
(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
increased susceptibility to induced colitis J:158426
Ptgs2tm2(Ptgs1)Fun/Ptgs2tm2(Ptgs1)Fun
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal macrophage physiology J:118171
Ptgs2tm2.1(Ptgs1)Fun/Ptgs2tm2.1(Ptgs1)Fun
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB)
abnormal macrophage physiology J:118171
kidney inflammation J:118171
peritoneal inflammation J:118171
Ptgs2ostm1Scrp/Ptgs2ostm1Scrp
(Not Specified)
abnormal chemokine level J:325487
decreased CCL3 level J:325487
decreased circulating CCL3 level J:325487
decreased circulating interleukin-6 level J:325487
decreased neutrophil cell number J:325487
increased interferon-beta secretion J:325487
Pth1rtm1a(EUCOMM)Hmgu/Pth1rtm1a(EUCOMM)Hmgu
(C57BL/6N-Pth1rtm1a(EUCOMM)Hmgu/Wtsi)
abnormal thymus morphology J:239583
blood in lymph vessels J:239583
enlarged lymphatic vessel J:239583
Pthtm1Dgo/Pthtm1Dgo
(involves: 129S2/SvPas * C57BL/6J)
abnormal osteoclast morphology J:76407
decreased osteoclast cell number J:76407
Pthtm1Dgo/Pthtm1Dgo
Pthlhtm1Hmk/Pthlhtm1Hmk

(involves: 129S2/SvPas * C57BL/6J)
abnormal osteoclast morphology J:76407
decreased osteoclast cell number J:76407
Pthlhtm1Ack/Pthlhtm1Ack
Tg(Col1a1-cre)1Ack/0

(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
abnormal osteoclast morphology J:100918
decreased osteoclast cell number J:100918
Pthlhtm1Ack/Pthlhtm1Hmk
Tg(LGB-cre)74Acl/0

(involves: 129 * C57BL/6 * CBA)
abnormal osteoclast morphology J:86536
Pthlhtm1Hmk/Pthlh+
(involves: 129S2/SvPas)
abnormal osteoclast morphology J:100918
Pthlhtm1Hmk/Pthlhtm1Hmk
(involves: 129S2/SvPas * C57BL/6J)
abnormal osteoclast morphology J:76407
decreased osteoclast cell number J:76407
Pthlhtm1Hmk/Pthlhtm1Hmk
Pth1rtm1Hmk/Pth1rtm2Hmk
Tg(Col2a1-PTHLH)1Ecw/0

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 * SJL)
abnormal bone marrow development J:99641
Pthlhtm2Ack/Pthlhtm2Ack
(involves: 129S2/SvPas * C57BL/6)
decreased osteoclast cell number J:142669
Ptk2btm1Schl/Ptk2btm1Schl
(involves: 129S1/Sv * 129X1/SvJ)
abnormal macrophage physiology J:99741
decreased acute inflammation J:99741
impaired macrophage chemotaxis J:99741
Ptntm1Tmu/Ptntm1Tmu
(B6.Cg-Ptntm1Tmu)
decreased macrophage cell number J:102069
impaired macrophage chemotaxis J:102069
impaired neutrophil recruitment J:102069
Ptp4a1em2(IMPC)Tcp/Ptp4a1em2(IMPC)Tcp
(C57BL/6NCrl-Ptp4a1em2(IMPC)Tcp/Tcp)
small spleen J:211773
Ptp4a2em1(IMPC)Tcp/Ptp4a2em1(IMPC)Tcp
(C57BL/6N-Ptp4a2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Ptp4a2Gt(AQ0673)Wtsi/Ptp4a2Gt(AQ0673)Wtsi
(involves: 129P2/OlaHsd * C57BL/6)
decreased spleen weight J:190411
Ptp4a3em1(IMPC)Mbp/Ptp4a3em1(IMPC)Mbp
(C57BL/6N-Ptp4a3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL)
immune system phenotype J:194929
Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL)
immune system phenotype J:194929
Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq
Tg(Lck-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL)
immune system phenotype J:194929
Ptpmt1tm2.1Ckq/Ptpmt1tm2.1Ckq
Tg(VAV1-cre)1Graf/0

(involves: 129S6/SvEvTac * C57BL/6J * SJL)
small spleen J:194929
small thymus J:194929
Ptpn2tm1.1Kry/Ptpn2tm1.1Kry
Tg(Col1a1-cre)1Kry/0

(involves: 129 * C57BL/6J * FVB)
abnormal osteoclast differentiation J:183709
abnormal osteoclast physiology J:183709
Ptpn2tm1Mtr/Ptpn2tm1Mtr
(involves: 129S4/SvJae * BALB/c)
abnormal B cell number J:42595
abnormal inflammatory response J:90541
abnormal spleen morphology J:42595
abnormal thymus involution J:42595
decreased B cell number J:42595
decreased double-positive T cell number J:42595
enlarged lymph nodes J:42595
enlarged spleen J:42595
increased B cell number J:42595
increased inflammatory response J:90541
increased interferon-gamma secretion J:90541
increased interleukin-12 secretion J:90541
increased macrophage cell number J:42595
increased mature B cell number J:42595
increased pre-B cell number J:42595
increased spleen red pulp amount J:42595
increased tumor necrosis factor secretion J:90541
lymph node hyperplasia J:42595
spleen hyperplasia J:42595
Ptpn2tm1Mtr/Ptpn2tm1Mtr
(C.129S4-Ptpn2tm1Mtr)
abnormal lymph node morphology J:186843
abnormal negative T cell selection J:186843
abnormal positive T cell selection J:186843
abnormal T cell differentiation J:186843
abnormal T cell subpopulation ratio J:186843
decreased B cell number J:186843
decreased B-1 B cell number J:186843
decreased CD4-positive, alpha-beta T cell number J:186843
decreased double-positive T cell number J:186843
decreased follicular B cell number J:186843
decreased immature B cell number J:186843
decreased marginal zone B cell number J:186843
decreased mature B cell number J:186843
decreased single-positive T cell number J:186843
decreased T cell number J:186843
decreased thymocyte number J:186843
enlarged spleen J:186843
increased splenocyte number J:186843
thymus atrophy J:186843
Ptpn2tm1Mtr/Ptpn2tm1Mtr
(B6.129S4(C)-Ptpn2tm1Mtr)
abnormal lymph node morphology J:186843
decreased B cell number J:186843
decreased B-1 B cell number J:186843
decreased CD4-positive, alpha-beta T cell number J:186843
decreased double-positive T cell number J:186843
decreased follicular B cell number J:186843
decreased immature B cell number J:186843
decreased marginal zone B cell number J:186843
decreased mature B cell number J:186843
decreased single-positive T cell number J:186843
decreased T cell number J:186843
decreased thymocyte number J:186843
thymus atrophy J:186843
Ptpn2tm2.1Ttig/Ptpn2tm2.1Ttig
(B6.Cg-Ptpn2tm2.1Ttig)
abnormal negative T cell selection J:186843
abnormal positive T cell selection J:186843
abnormal T cell differentiation J:186843
abnormal T cell subpopulation ratio J:186843
decreased B cell number J:186843
decreased B-1 B cell number J:186843
decreased CD4-positive, alpha-beta T cell number J:186843
decreased double-positive T cell number J:186843
decreased follicular B cell number J:186843
decreased immature B cell number J:186843
decreased marginal zone B cell number J:186843
decreased mature B cell number J:186843
decreased single-positive T cell number J:186843
decreased thymocyte number J:186843
enlarged lymph nodes J:186843
thymus atrophy J:186843
Ptpn3tm1Pdk/Ptpn3tm1Pdk
Ptpn4Gt(OST146128)Lex/Ptpn4Gt(OST146128)Lex

(involves: 129S5/SvEvBrd * C57BL/6)
immune system phenotype J:144351
Ptpn4Gt(OST146128)Lex/Ptpn4Gt(OST146128)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
immune system phenotype J:144351
Ptpn4tm1.1Oers/Ptpn4tm1.1Oers
(B6.129S6-Ptpn4tm1.1Oers)
immune system phenotype J:138871
Ptpn6em1.1Shoy/Ptpn6em1.1Shoy
(involves: C57BL/6)
decreased thymocyte number J:236298
Ptpn6m1Amgn/Ptpn6m1Amgn
(involves: C3H/HeSnJ * C57BL/6J * Swiss)
increased circulating interleukin-17 level J:168664
Ptpn6m1Anu/Ptpn6m1Anu
(C57BL/6JAnu-Ptpn6m1Anu)
decreased IgM level J:225105
Ptpn6m1Btlr/Ptpn6m1Btlr
(C57BL/6J-Ptpn6m1Btlr/Mmucd)
abnormal myeloid leukocyte morphology J:142845
decreased mature B cell number J:142845
decreased susceptibility to bacterial infection J:142845
decreased susceptibility to bacterial infection induced morbidity/mortality J:142845
enlarged spleen J:94077, J:142845
increased anti-chromatin antibody level J:142845
increased IgM level J:142845
increased inflammatory response J:94077
increased neutrophil cell number J:142845
lung inflammation J:142845
salivary gland inflammation J:142845
Ptpn6m3Btlr/Ptpn6+
(C57BL/6J-Ptpn6m3Btlr)
abnormal CD8-positive, alpha beta T cell morphology J:234259
decreased B cell number J:234259
decreased B-2 B cell number J:234259
decreased immature B cell number J:234259
decreased mature B cell number J:234259
increased B-1 B cell number J:234259
increased B-1a cell number J:234259
increased dendritic cell number J:234259
increased macrophage cell number J:234259
Ptpn6m3Btlr/Ptpn6m3Btlr
(C57BL/6J-Ptpn6m3Btlr)
abnormal CD8-positive, alpha beta T cell morphology J:234259
decreased B cell number J:234259
decreased B-2 B cell number J:234259
decreased immature B cell number J:234259
decreased mature B cell number J:234259
increased B-1 B cell number J:234259
increased B-1b cell number J:234259
increased dendritic cell number J:234259
increased macrophage cell number J:234259
Ptpn6m4Btlr/Ptpn6m4Btlr
(C57BL/6J-Ptpn6m4Btlr)
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:264807
decreased CD8-positive, naive alpha-beta T cell number J:264807
increased B-1 B cell number J:264807
increased CD8-positive, alpha-beta memory T cell number J:264807
increased central memory CD8 positive, alpha-beta T cell number J:264807
increased effector memory CD4-positive, alpha-beta T cell number J:264807
increased effector memory CD8-positive, alpha-beta T cell number J:264807
Ptpn6M5Btlr/Ptpn6M5Btlr
(C57BL/6J-Ptpn6M5Btlr)
decreased B cell number J:265075
decreased B-1 B cell number J:265075
decreased CD8-positive, naive alpha-beta T cell number J:265075
decreased IgD level J:265075
decreased IgM level J:265075
increased central memory CD8 positive, alpha-beta T cell number J:265075
Ptpn6m6Btlr/Ptpn6m6Btlr
(C57BL/6J-Ptpn6m6Btlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:272439
abnormal T cell differentiation J:272439
Ptpn6m7Btlr/Ptpn6m7Btlr
(C57BL/6J-Ptpn6m7Btlr)
abnormal T cell differentiation J:272440
Ptpn6me-B2/Ptpn6me-B2
(involves: BALB/c)
abnormal circulating chemokine level J:169850
increased circulating interferon-gamma level J:169850
increased circulating interleukin-1 beta level J:169850
increased circulating interleukin-6 level J:169850
increased circulating interleukin-10 level J:169850
increased circulating serum amyloid protein level J:169850
increased IgG level J:169850
increased IgM level J:169850
increased neutrophil cell number J:169850
interstitial pneumonia J:169850
skin inflammation J:169850
small thymus J:169850
Ptpn6me-v/Ptpn6+
Tg(IghelMD4)4Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mature B cell morphology J:110531
Ptpn6me-v/Ptpn6me-v
(C57BL/6J-Ptpn6me-v)
abnormal immunoglobulin level J:7665
abnormal inflammatory response J:20845
abnormal plasma cell morphology J:14936
abnormal T cell physiology J:1661
abnormal thymus development J:16613
chronic inflammation J:20845
decreased B cell number J:113218
decreased mature B cell number J:7905
increased plasma cell number J:7905
interstitial pneumonia J:7531
rheumatoid arthritis J:20845
Ptpn6me/Ptpn6me
(C57BL/6J-Ptpn6me/J)
abnormal granulocyte morphology J:5579
abnormal humoral immune response J:5579
abnormal immune system cell morphology J:5579
abnormal leukocyte cell number J:5579
abnormal Peyer's patch morphology J:5579
abnormal thymus morphology J:5579
autoimmune response J:5579
enlarged spleen J:5579
increased granulocyte number J:5579
increased IgA level J:5579
increased IgG level J:5579
increased IgM level J:5579
increased immunoglobulin level J:5579
increased leukocyte cell number J:5579
increased monocyte cell number J:5579
small thymus J:5579
Ptpn6me/Ptpn6me
(involves: C3H/HeN * C57BL/6J * NFS)
increased autoantibody level J:30994
increased IgM level J:30994
increased splenocyte proliferation J:30994
Ptpn6me/Ptpn6me
(involves: C3HeB/FeJ * C57BL/6)
abnormal microglial cell morphology J:72655
Ptpn6me/Ptpn6me
(C3FeLe.B6 a/a-Ptpn6me/J)
increased microglial cell activation J:88807
Ptpn6me/Ptpn6me
(either: (involves: C3H * C57BL/6J) or (involves: C57BL/6J * C57BL/6N))
lung inflammation J:5999
thymus atrophy J:5999
Ptpn9tm1Dny/Ptpn9tm1Dny
(B6.129-Ptpn9tm1Dny)
abnormal T cell differentiation J:118880
decreased T cell proliferation J:118880
Ptpn11tm1.1Ics/Ptpn11+
(involves: 129S2/SvPas * C57BL/6 * FVB/N)
enlarged spleen J:216593
Ptpn11tm1Bgn/Ptpn11+
(involves: 129S4/SvJae * C57BL/6J)
enlarged spleen J:91609
increased leukocyte cell number J:91609
increased lymphocyte cell number J:91609
increased neutrophil cell number J:91609
myeloid hyperplasia J:91609
Ptpn11tm1Ckq/Ptpn11+
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J)
myeloid hyperplasia J:177285
Ptpn11tm1Ckq/Ptpn11+
Tg(Lck-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6J)
immune system phenotype J:177285
Ptpn11tm1Ckq/Ptpn11+
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA)
arrested B cell differentiation J:177285
enlarged spleen J:177285
increased leukocyte cell number J:177285
increased neutrophil cell number J:177285
increased spleen weight J:177285
myeloid hyperplasia J:177285
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA)
increased acute inflammation J:172422
increased circulating interleukin-6 level J:172422
liver inflammation J:172422
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Stat3tm1Vpo/Stat3tm1Vpo
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA)
liver inflammation J:172422
Ptpn11tm6Bgn/Ptpn11+
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
abnormal leukopoiesis J:148430
Ptpn11tm6Bgn/Ptpn11+
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
abnormal leukopoiesis J:148430
abnormal splenic cell ratio J:148430
enlarged spleen J:148430
increased granulocyte number J:148430
increased leukocyte cell number J:148430
increased monocyte cell number J:148430
intermingled spleen red and white pulp J:148430
Ptpn12tm1Vei/Ptpn12tm1Vei
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Tg(Cd4-cre)1Cwi Ptpn12tm1Vei)
abnormal cytokine secretion J:163910
abnormal T cell physiology J:163910
decreased T cell proliferation J:163910
Ptpn12tm1Vei/Ptpn12tm1Vei
Tg(Lck-cre)1Cwi/0

(B6.Cg-Ptpn12tm1Vei Tg(Lck-cre)1Cwi)
decreased susceptibility to experimental autoimmune encephalomyelitis J:163910
Ptpn13tm1Gru/Ptpn13tm1Gru
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:118426
abnormal cytokine secretion J:118426
decreased susceptibility to bacterial infection J:118426
Ptpn13tm1Wjh/Ptpn13tm1Wjh
(involves: 129P2/OlaHsd * C57BL/6)
increased T-helper 2 cell number J:144351
Ptpn13tm1Wjh/Ptpn13tm1Wjh
Ptpn3tm1Pdk/Ptpn3tm1Pdk
Ptpn4Gt(OST146128)Lex/Ptpn4Gt(OST146128)Lex

(involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6)
immune system phenotype J:144351
Ptpn14Gt(RRR484)Byg/Ptpn14Gt(RRR484)Byg
(involves: 129P2/OlaHsd)
lymphatic vessel hyperplasia J:169186
Ptpn22tm1.1Draw/Ptpn22+
(involves: 129 * C57BL/6)
abnormal B cell differentiation J:201448
abnormal B cell morphology J:201448
abnormal B cell number J:201448
abnormal B cell physiology J:201448
abnormal T cell morphology J:201448
abnormal T cell number J:201448
abnormal T cell physiology J:201448
abnormal thymus morphology J:201448
autoimmune response J:201448
decreased B cell apoptosis J:201448
decreased follicular B cell number J:201448
decreased mature B cell number J:201448
enlarged spleen J:201448
increased anti-double stranded DNA antibody level J:201448
increased B cell number J:201448
increased B cell proliferation J:201448
increased CD4-positive, alpha-beta memory T cell number J:201448
increased double-positive T cell number J:201448
increased germinal center B cell number J:201448
increased IgG1 level J:201448
increased interleukin-2 secretion J:201448
increased regulatory T cell number J:201448
increased spleen germinal center size J:201448
increased T cell proliferation J:201448
increased transitional stage T1 B cell number J:201448
spleen hyperplasia J:201448
thymus hyperplasia J:201448
Ptpn22tm1.1Draw/Ptpn22tm1.1Draw
(involves: 129 * C57BL/6)
abnormal B cell activation J:201448
abnormal B cell differentiation J:201448
abnormal B cell morphology J:201448
abnormal B cell physiology J:201448
abnormal T cell differentiation J:201448
abnormal T cell morphology J:201448
abnormal T cell physiology J:201448
abnormal thymus morphology J:201448
autoimmune response J:201448
decreased B cell apoptosis J:201448
decreased follicular B cell number J:201448
decreased mature B cell number J:201448
enlarged spleen J:201448
glomerulonephritis J:201448
immune system phenotype J:201448
increased anti-double stranded DNA antibody level J:201448
increased anti-insulin autoantibody level J:201448
increased B cell number J:201448
increased B cell proliferation J:201448
increased double-positive T cell number J:201448
increased effector memory CD4-positive, alpha-beta T cell number J:201448
increased effector memory CD8-positive, alpha-beta T cell number J:201448
increased germinal center B cell number J:201448
increased IgE level J:201448
increased IgG1 level J:201448
increased IgG3 level J:201448
increased IgM level J:201448
increased inflammatory response J:201448
increased interleukin-2 secretion J:201448
increased regulatory T cell number J:201448
increased spleen germinal center size J:201448
increased T cell proliferation J:201448
increased transitional stage T1 B cell number J:201448
spleen hyperplasia J:201448
thymus hyperplasia J:201448
Ptpn22tm1.1Kas/Ptpn22tm1.1Kas
(involves: C57BL/6)
abnormal dendritic cell physiology J:176519
enlarged spleen J:176519
enlarged thymus J:176519
immune system phenotype J:176519
increased B cell proliferation J:176519
increased CD4-positive, alpha-beta T cell number J:176519
increased CD8-positive, alpha-beta T cell number J:176519
increased dendritic cell number J:176519
increased IgG2a level J:176519
increased IgG3 level J:176519
increased IgM level J:176519
increased interleukin-12 secretion J:176519
increased spleen germinal center number J:176519
increased spleen germinal center size J:176519
increased T cell number J:176519
increased T cell proliferation J:176519
Ptpn22tm1.1Kas/Ptpn22tm1.1Kas
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C57BL/6 * C57BL/6J * DBA/2J)
immune system phenotype J:176519
Ptpn22tm1.1Kas/Ptpn22tm1.1Kas
Tg(TcraTcrb)425Cbn/0

(involves: BALB/c * C57BL/6)
increased CD4-positive, alpha-beta T cell number J:176519
increased T cell proliferation J:176519
Ptpn22tm1Achn/Ptpn22tm1Achn
(involves: C57BL/6)
abnormal Peyer's patch germinal center morphology J:90029
abnormal T cell physiology J:90029
enlarged lymph nodes J:90029
enlarged spleen J:90029
increased B cell number J:90029
increased follicular B cell number J:90029
increased IgE level J:90029
increased IgG1 level J:90029
increased IgG2a level J:90029
increased spleen germinal center number J:90029
Ptpn22tm2Achn/Ptpn22tm2Achn
(involves: C57BL/6)
abnormal Peyer's patch germinal center morphology J:90029
abnormal T cell physiology J:90029
enlarged lymph nodes J:90029
enlarged spleen J:90029
increased B cell number J:90029
increased follicular B cell number J:90029
increased IgE level J:90029
increased IgG1 level J:90029
increased IgG2a level J:90029
increased spleen germinal center number J:90029
Ptpn22tm2Achn/Ptpn22tm2Achn
(B6.Cg-Ptpn22tm2Achn)
abnormal double-positive T cell morphology J:147129
abnormal T cell activation J:147129
abnormal T cell subpopulation ratio J:147129
abnormal thymocyte activation J:147129
enlarged lymph nodes J:147129
increased memory T cell number J:147129
Ptpn22tm2Achn/Ptpn22tm2Achn
Ptprctm1Weis/Ptprctm1Weis

(B6.Cg-Ptprctm1Weis Ptpn22tm2Achn)
abnormal B cell activation J:147129
abnormal double-positive T cell morphology J:147129
abnormal follicular B cell physiology J:147129
abnormal lymphocyte cell number J:147129
abnormal T cell activation J:147129
abnormal T cell subpopulation ratio J:147129
abnormal thymocyte activation J:147129
decreased follicular B cell number J:147129
enlarged lymph nodes J:147129
glomerulonephritis J:147129
increased autoantibody level J:147129
increased memory T cell number J:147129
increased plasma cell number J:147129
increased transitional stage B cell number J:147129
liver inflammation J:147129
lung inflammation J:147129
Ptprcloc/Ptprcloc
(C57BL/6JSfdAnu-Ptprcloc/AnuApb)
abnormal B cell number J:104190
abnormal double-positive T cell morphology J:104190
abnormal memory T cell number J:104190
abnormal T cell morphology J:104190
abnormal T cell selection J:104190
abnormal thymocyte activation J:104190
arrested T cell differentiation J:104190
decreased CD4-positive, alpha-beta T cell number J:104190
decreased CD8-positive, alpha-beta T cell number J:104190
decreased double-positive T cell number J:104190
decreased T cell number J:104190
Ptprcltng/Ptprcltng
(C57BL/6-Ptprcltng)
abnormal T cell differentiation J:158876
decreased CD4-positive, alpha-beta T cell number J:158876
decreased double-positive T cell number J:158876
thymus hypoplasia J:158876
Ptprcltng/Ptprctm1Mak
(involves: 129/Sv * C57BL/6)
abnormal T cell differentiation J:158876
decreased CD4-positive, alpha-beta T cell number J:158876
decreased double-positive T cell number J:158876
thymus hypoplasia J:158876
Ptprcltng/Ptprctm1Mak
Tg(TcraTcrb)425Cbn/0

(involves: 129/Sv * BALB/c * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:158876
thymus hypoplasia J:158876
Ptprcm1Btlr/Ptprcm1Btlr
(involves: C57BL/6J)
absent T cells J:152064
Ptprcm1Smv/Ptprcm1Smv
(involves: C57BL/6J * C57BL/10J)
abnormal CD4-positive T cell differentiation J:214487
abnormal CD8-positive, alpha-beta T cell differentiation J:214487
abnormal immune system cell morphology J:214487
abnormal immune system physiology J:214487
CNS inflammation J:214487
decreased DN4 thymocyte number J:214487
increased DN3 thymocyte number J:214487
increased double-negative T cell number J:214487
increased susceptibility to Herpesvirales infection J:214487
Ptprcm2Btlr/Ptprcm2Btlr
(C57BL/6J-Ptprcm2Btlr)
abnormal humoral immune response J:216796
decreased B-1a cell number J:216796
decreased B-2 B cell number J:216796
decreased CD4-positive, alpha-beta memory T cell number J:216796
decreased CD8-positive, alpha-beta memory T cell number J:216796
decreased mature B cell number J:216796
decreased memory B cell number J:216796
decreased memory T cell number J:216796
decreased single-positive T cell number J:216796
increased B-1 B cell number J:216796
increased B-1b cell number J:216796
increased dendritic cell number J:216796
increased neutrophil cell number J:216796
increased single-positive T cell number J:216796
Ptprcm3Btlr/Ptprcm3Btlr
(C57BL/6J-Ptprcm3Btlr)
decreased B cell number J:254899
decreased B-1a cell number J:254899
decreased B-2 B cell number J:254899
decreased CD8-positive, alpha-beta T cell number J:254899
increased B-1b cell number J:254899
Ptprcm4Btlr/Ptprcm4Btlr
(C57BL/6J-Ptprcm4Btlr)
decreased B cell number J:264808
decreased CD4-positive, alpha-beta T cell number J:264808
decreased CD8-positive, alpha-beta T cell number J:264808
decreased CD8-positive, naive alpha-beta T cell number J:264808
decreased single-positive T cell number J:264808
decreased T cell number J:264808
increased B-1 B cell number J:264808
increased central memory CD4-positive, alpha-beta T cell number J:264808
increased central memory CD8 positive, alpha-beta T cell number J:264808
increased effector memory CD4-positive, alpha-beta T cell number J:264808
increased effector memory CD8-positive, alpha-beta T cell number J:264808
PtprcM5Btlr/PtprcM5Btlr
(C57BL/6J-PtprcM5Btlr)
increased alpha-beta T cell number J:265143
PtprcM6Btlr/PtprcM6Btlr
(C57BL/6J-PtprcM6Btlr)
decreased B-1a cell number J:265186
decreased B-1b cell number J:265186
decreased CD8-positive, naive alpha-beta T cell number J:265186
increased B-1 B cell number J:265186
Ptprcm7Btlr/Ptprcm7Btlr
(C57BL/6J-Ptprcm7Btlr)
decreased alpha-beta T cell number J:267486
decreased B cell number J:267486
decreased CD4-positive, alpha-beta T cell number J:267486
decreased CD8-positive, alpha-beta T cell number J:267486
decreased CD8-positive, naive alpha-beta T cell number J:267486
decreased NK T cell number J:267486
increased B-1 B cell number J:267486
increased central memory CD4-positive, alpha-beta T cell number J:267486
increased central memory CD8 positive, alpha-beta T cell number J:267486
increased effector memory CD4-positive, alpha-beta T cell number J:267486
increased effector memory CD8-positive, alpha-beta T cell number J:267486
PtprcM8Btlr/PtprcM8Btlr
(C57BL/6J-PtprcM8Btlr)
increased B-1 B cell number J:267487
increased central memory CD8 positive, alpha-beta T cell number J:267487
PtprcM9Btlr/PtprcM9Btlr
(C57BL/6J-PtprcM9Btlr)
abnormal B cell differentiation J:272745
abnormal CD8-positive, alpha beta T cell morphology J:272745
abnormal lymphocyte morphology J:272745
decreased B cell number J:272745
decreased NK cell number J:272745
increased CD8-positive, alpha-beta T cell number J:272745
increased effector memory CD4-positive, alpha-beta T cell number J:272745
PtprcM10Btlr/PtprcM10Btlr
(C57BL/6J-PtprcM10Btlr)
decreased B-1b cell number J:272777
decreased IgE level J:272777
PtprcM11Btlr/PtprcM11Btlr
(C57BL/6J-PtprcM11Btlr)
abnormal B cell differentiation J:274863
abnormal CD8-positive, alpha-beta T cell differentiation J:274863
increased B-1 B cell number J:274863
Ptprcm12Btlr/Ptprcm12Btlr
(C57BL/6J-Ptprcm12Btlr)
decreased B cell number J:274972
decreased CD4-positive, alpha-beta T cell number J:274972
decreased CD8-positive, alpha-beta T cell number J:274972
decreased CD8-positive, naive alpha-beta T cell number J:274972
decreased central memory CD8 positive, alpha-beta T cell number J:274972
decreased effector memory CD4-positive, alpha-beta T cell number J:274972
decreased T cell number J:274972
increased B-1 B cell number J:274972
Ptprcnim/Ptprcnim
(C57BL/6JAnu-Ptprcnim)
decreased B cell number J:225105
decreased leukocyte cell number J:225105
decreased T cell number J:225105
Ptprcrain/Ptprcrain
(C57BL/6JAnu-Ptprcrain/AnuApb)
abnormal leukocyte morphology J:104190
Ptprcstrm/Ptprcstrm
(C57BL/6JAnu-Ptprcstrm/AnuApb)
decreased B cell number J:104190
decreased T cell number J:104190
Ptprctm1Holm/Ptprctm1Holm
(involves: 129/Sv * C57BL/6)
abnormal B cell number J:33466
abnormal lymphopoiesis J:33466
abnormal T cell differentiation J:33466
decreased CD4-positive, alpha-beta T cell number J:33466
decreased CD8-positive, alpha-beta T cell number J:33466
decreased double-positive T cell number J:33466
decreased T cell number J:33466
decreased thymocyte number J:33466
increased double-negative T cell number J:33466
spleen hyperplasia J:33466
Ptprctm1Holm/Ptprctm1Holm
Tg(Lck*F505)2964Rmp/?

(involves: 129/Sv * C57BL/6 * DBA/2)
thymus hyperplasia J:64671
Ptprctm1Holm/Ptprctm1Holm
Tg(Lck*F505)3073Rmp/?

(involves: 129/Sv * C57BL/6 * DBA/2)
thymus hyperplasia J:64671
Ptprctm1Mak/Ptprctm1Mak
(involves: 129/Sv * C57BL/6)
abnormal response to infection J:13163
abnormal T cell subpopulation ratio J:13163
arrested T cell differentiation J:158876
decreased B cell proliferation J:13163
decreased CD4-positive, alpha-beta T cell number J:13163
decreased CD8-positive, alpha-beta T cell number J:13163
decreased cytotoxic T cell cytolysis J:13163
decreased T cell number J:13163
decreased T cell proliferation J:13163
decreased thymocyte number J:13163
increased double-negative T cell number J:13163
Ptprctm1Mak/Ptprctm1Mak
(involves: 129)
abnormal osteoclast morphology J:141275
abnormal osteoclast physiology J:141275
decreased mast cell degranulation J:110782
decreased susceptibility to type I hypersensitivity reaction J:110782
Ptprctm1Mak/Ptprctm1Mak
(B6.Cg-Ptprctm1Mak)
abnormal CD4-positive, alpha-beta intraepithelial T cell morphology J:111646
abnormal intraepithelial T cell morphology J:111646
abnormal intraepithelial T cell number J:111646
abnormal NK cell physiology J:109462
abnormal T cell differentiation J:111646
decreased cytotoxic T cell cytolysis J:111646
decreased gamma-delta intraepithelial T cell number J:111646
increased T cell apoptosis J:111646
Ptprctm1Mak/Ptprctm1Mak
Ptprjtm1.2Weis/Ptprjtm1.2Weis

(involves: 129/Sv * 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal B cell physiology J:131736
abnormal cytokine secretion J:131736
abnormal follicular B cell morphology J:131736
abnormal myelopoiesis J:131736
decreased B cell number J:131736
impaired macrophage phagocytosis J:131736
Ptprctm1Mak/Ptprctm1Mak
Ptprjtm1.2Weis/Ptprjtm1.2Weis

(B6.Cg-Ptprctm1Mak Ptprjtm1.2Weis)
abnormal B cell differentiation J:131736
abnormal follicular B cell morphology J:131736
abnormal myelopoiesis J:131736
abnormal spleen morphology J:131736
abnormal transitional stage B cell morphology J:131736
decreased B cell number J:131736
decreased immature B cell number J:131736
decreased mature B cell number J:131736
liver inflammation J:131736
lung inflammation J:131736
Ptprctm1Mak/Ptprctm1Mak
Tg(TcraTcrb)425Cbn/0

(involves: 129/Sv * BALB/c * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:158876
Ptprctm1Tyb/Ptprctm1Tyb
(C.129S2-Ptprctm1Tyb)
abnormal positive T cell selection J:57681
abnormal T cell differentiation J:57681
abnormal T cell physiology J:57681
decreased CD4-positive, alpha-beta T cell number J:57681
decreased CD8-positive, alpha-beta T cell number J:57681
decreased double-positive T cell number J:57681
enlarged spleen J:57681
immune system phenotype J:57681
increased double-negative T cell number J:57681
thymus hypoplasia J:57681
Ptprctm1Tyb/Ptprctm1Tyb
(B6.129S2-Ptprctm1Tyb)
abnormal chemokine secretion J:98190
abnormal cytokine secretion J:98190
abnormal NK cell physiology J:98190
increased NK cell number J:98190
Ptprctm1Weis/Ptprc+
(involves: 129X1/SvJ * C57BL/6)
increased anti-double stranded DNA antibody level J:66501
increased IgG2a level J:66501
increased susceptibility to autoimmune disorder J:66501
Ptprctm1Weis/Ptprctm1Weis
(involves: 129X1/SvJ * C57BL/6)
abnormal B cell activation J:66501
abnormal granulocyte differentiation J:66501
abnormal immune system organ morphology J:66501
abnormal leukocyte cell number J:66501
abnormal T cell activation J:66501
enlarged lymph nodes J:66501
enlarged spleen J:66501
glomerulonephritis J:66501
increased anti-double stranded DNA antibody level J:66501
increased B cell number J:66501
increased IgA level J:66501
increased IgG2a level J:66501
increased plasmacytoid dendritic cell number J:66501
increased spleen red pulp amount J:66501
increased spleen white pulp amount J:66501
increased susceptibility to autoimmune disorder J:66501
increased T cell number J:66501
lymph node hyperplasia J:66501
Ptprctm1Weis/Ptprctm1Weis
(B6.129X1-Ptprctm1Weis)
abnormal B cell activation J:147129
abnormal double-positive T cell morphology J:147129
abnormal follicular B cell physiology J:147129
abnormal T cell activation J:147129
abnormal T cell subpopulation ratio J:147129
abnormal thymocyte activation J:147129
decreased follicular B cell number J:147129
enlarged lymph nodes J:147129
immune system phenotype J:109462
increased memory T cell number J:147129
increased plasma cell number J:147129
increased transitional stage B cell number J:147129
liver inflammation J:147129
lung inflammation J:147129
Ptprcaptm1Svn/Ptprcaptm1Svn
(involves: C57BL/6)
enlarged lymph nodes J:58712
lymphoid hyperplasia J:58712
Ptprcaptm1Tho/Ptprcaptm1Tho
(involves: 129X1/SvJ)
immune system phenotype J:58711
Ptprcaptm1Tkda/Ptprcaptm1Tkda
(involves: 129X1/SvJ)
abnormal cytotoxic T cell physiology J:48387
decreased B cell proliferation J:48387
decreased T cell proliferation J:48387
immune system phenotype J:48387
Ptprdtm2a(KOMP)Wtsi/Ptprdtm2a(KOMP)Wtsi
(C57BL/6N-Ptprdtm2a(KOMP)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Ptpretm1Ael/Ptpretm1Ael
(involves: 129S6/SvEvTac * C57BL/6)
abnormal osteoclast differentiation J:90031
abnormal osteoclast physiology J:90031
Ptprftm1Wjh/Ptprftm1Wjh
(involves: 129P2/OlaHsd)
immune system phenotype J:119456
Ptprjtm1.2Weis/Ptprjtm1.2Weis
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
abnormal B cell differentiation J:131736
abnormal splenic cell ratio J:131736
increased B-2 B cell number J:131736
increased marginal zone B cell number J:131736
Ptprntm1Aln/Ptprntm1Aln
(NOD.129S4-Ptprntm1Aln)
increased susceptibility to autoimmune diabetes J:107161
insulitis J:107161
Ptprz1tm1Mno/Ptprz1tm1Mno
(B6.129-Ptprz1tm1Mno)
decreased susceptibility to bacterial infection J:85826
Ptprz1tm1Schl/Ptprz1tm1Schl
(involves: 129 * Swiss Webster)
increased susceptibility to experimental autoimmune encephalomyelitis J:79860
Ptrh2tm1.1Eruo/Ptrh2tm1.1Eruo
(C57BL/6-Ptrh2tm1.1Eruo)
decreased neutrophil cell number J:131853
Ptstm1b(EUCOMM)Wtsi/Pts+
(C57BL/6N-Ptstm1b(EUCOMM)Wtsi/H)
increased large unstained cell number J:211773
Pttg1tm1b(EUCOMM)Wtsi/Pttg1tm1b(EUCOMM)Wtsi
(C57BL/6N-Pttg1tm1b(EUCOMM)Wtsi/Tcp)
small spleen J:211773
Pttg1tm1Sme/Pttg1tm1Sme
(involves: 129S4/SvJae * C57BL/6)
abnormal immune system organ morphology J:72267
decreased IgG level J:72267
decreased IgM level J:72267
decreased immunoglobulin level J:72267
decreased spleen weight J:72267
increased T cell number J:72267
thymus hyperplasia J:72267
Ptx3tm1Mant/Ptx3tm1Mant
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
abnormal dendritic cell physiology J:85080
abnormal macrophage physiology J:85080
abnormal professional antigen presenting cell physiology J:85080
abnormal T-helper 1 physiology J:85080
impaired macrophage phagocytosis J:85080
increased susceptibility to bacterial infection J:85080
increased susceptibility to fungal infection J:85080
lung inflammation J:85080
Ptx3tm1Zuk/Ptx3tm1Zuk
(involves: 129S7/SvEvBrd * C57BL/6J)
increased susceptibility to Coronaviridae infection J:188421
Puf60tm1.1Kmtsu/Puf60+
Trp53tm1Sia/Trp53tm1Sia

(involves: C57BL/6NCrlj * C57BL/6NCrSlc * CBA/JNCrlj)
increased leukocyte cell number J:233347
increased spleen weight J:233347
increased thymus weight J:233347
Pum1em1(IMPC)Mbp/Pum1em1(IMPC)Mbp
(C57BL/6NCrl-Pum1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Puratm1Kkh/Puratm1Kkh
(involves: 129)
abnormal spleen morphology J:85759
abnormal thymus morphology J:85759
decreased spleen weight J:85759
small spleen J:85759
Pvrtm1Gbn/Pvrtm1Gbn
(either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * BALB/c))
abnormal response to infection J:123540
decreased IgA level J:123540
decreased IgG1 level J:123540
decreased IgG2a level J:123540
decreased IgG2b level J:123540
decreased IgG level J:123540
Pvrigem1(IMPC)Mbp/Pvrigem1(IMPC)Mbp
(C57BL/6N-Pvrigem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Pvrigtm1.2Sgng/Pvrigtm1.2Sgng
(B6(Cg)-Pvrigtm1.1Sgng)
abnormal CD8-positive, alpha-beta T cell physiology J:324171
abnormal T cell physiology J:324171
Pwwp3aem1(IMPC)Tcp/Pwwp3aem1(IMPC)Tcp
(C57BL/6NCrl-Pwwp3aem1(IMPC)Tcp/Tcp)
small thymus J:211773
Pxdnmhdakta048/Pxdnmhdakta048
(involves: C3HeB/FeJ * C57BL/6J)
eye inflammation J:213336
Pycardtm1Ayaz/Pycardtm1Ayaz
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6J)
decreased interleukin-1 alpha secretion J:191239
decreased interleukin-1 beta secretion J:191239
decreased interleukin-6 secretion J:191239
decreased tumor necrosis factor secretion J:191239
Pycardtm1Flv/Pycardtm1Flv
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal macrophage physiology J:113333
decreased circulating interleukin-1 beta level J:113333
decreased circulating interleukin-18 level J:113333, J:158969
decreased interleukin-1 alpha secretion J:113333
decreased interleukin-1 beta secretion J:113333
decreased NK cell number J:158969
decreased susceptibility to endotoxin shock J:113333
decreased susceptibility to type IV hypersensitivity reaction J:113333
increased susceptibility to Herpesvirales infection J:158969
Pycardtm1Flv/Pycardtm1Flv
(B6.129S5-Pycardtm1Flv)
enlarged Peyer's patches J:173245
increased IgA level J:173245
increased IgG2c level J:173245
increased susceptibility to induced colitis J:173245
Pycardtm1Flv/Pycardtm1Flv
Slc11a1s/Slc11a1s

(B6.129S5-Pycardtm1Flv)
increased susceptibility to bacterial infection J:124378
Pycardtm1Nnz/Pycardtm1Nnz
(involves: 129 * C57BL/6)
decreased interleukin-1 beta secretion J:129871
decreased interleukin-18 secretion J:129871
Pycardtm1Tno/Pycardtm1Tno
(involves: 129S4/SvJae * C57BL/6)
decreased interferon-gamma secretion J:100807
decreased interleukin-1 beta secretion J:100807
decreased interleukin-18 secretion J:100807
decreased susceptibility to endotoxin shock J:100807
Pycardtm1Vmd/Pycardtm1Vmd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N)
decreased inflammatory response J:91292
decreased interleukin-1 alpha secretion J:91292
decreased interleukin-1 beta secretion J:91292
decreased interleukin-18 secretion J:91292
Pycardtm1Vmd/Pycardtm1Vmd
(involves: 129S1/Sv * 129X1/SvJ)
abnormal response to infection J:106976
decreased interleukin-1 beta secretion J:124226, J:106976
decreased interleukin-18 secretion J:106976
Pycardtm1Vmd/Pycardtm1Vmd
(B6.129-Pycardtm1Vmd)
abnormal macrophage physiology J:160545
decreased circulating interleukin-1 beta level J:193522
decreased circulating interleukin-18 level J:193522
decreased interleukin-1 beta secretion J:193522, J:160545
decreased susceptibility to endotoxin shock J:193522
increased interferon-beta secretion J:160545
increased tumor necrosis factor secretion J:160545
Pycr2m1J/Pycr2m1J
(involves: C3H/HeJ * C57BL/6J)
decreased basophil cell number J:308336
decreased leukocyte cell number J:308336
decreased lymphocyte cell number J:308336
Pycr2tm1a(EUCOMM)Wtsi/Pycr2tm1a(EUCOMM)Wtsi
(C57BL/6N-Pycr2tm1a(EUCOMM)Wtsi/Wtsi)
decreased Ly6C low monocyte number J:211773
decreased monocyte cell number J:211773
Pygltm1a(KOMP)Wtsi/Pygltm1a(KOMP)Wtsi
(C57BL/6N-Pygltm1a(KOMP)Wtsi)
liver inflammation J:284765
Pymr129X1/SvJMs/PymrNC/JicJcl
(involves: 129X1/SvJMs * NC/JicJcl)
decreased susceptibility to parasitic infection J:92924
PymrNC/JicJcl/PymrNC/JicJcl
(involves: 129X1/SvJMs * NC/JicJcl)
increased susceptibility to parasitic infection J:92924
Pzptm1Vln/Pzptm1Vln
(involves: 129P2/OlaHsd * C57BL)
increased susceptibility to induced pancreatitis J:28328
pancreas inflammation J:28328
Pzptm1Vln/Pzptm1Vln
(B.129P2-Pzptm1Vln)
abnormal cytokine level J:57485
liver inflammation J:57485
Pzptm1Vln/Pzptm1Vln
(B6.129P2-Pzptm1Vln)
abnormal cytokine secretion J:113532
Qpcttm1.1Gne/Qpcttm1.1Gne
(C57BL/6N-Qpcttm1.1Gne)
immune system phenotype J:324112
Qpcttm1.1Gne/Qpcttm1.1Gne
Qpctltm1.1Gne/Qpctltm1.1Gne

(C57BL/6N-Qpctltm1.1Gne Qpcttm1.1Gne)
decreased monocyte cell number J:324112
Qpctltm1.1Gne/Qpctltm1.1Gne
(C57BL/6N-Qpctltm1.1Gne)
decreased monocyte cell number J:324112
increased monocyte cell number J:324112
QprtGt(OST337946)Lex/QprtGt(OST337946)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal cytokine level J:282516
abnormal macrophage morphology J:282516
abnormal macrophage physiology J:282516
Qrich1b2b2404Clo/Qrich1b2b2404Clo
(C57BL/6J-Qrich1b2b2404Clo)
thymus hypoplasia J:175213
Qsox1b2b2673Clo/Qsox1b2b2673Clo
(C57BL/6J-Qsox1b2b2673Clo)
spleen hypoplasia J:175213
Rab2aem2(IMPC)Tcp/Rab2a+
(C57BL/6NCrl-Rab2aem2(IMPC)Tcp/Tcp)
increased spleen weight J:211773
Rab6bGt(OST68543)Lex/Rab6bGt(OST68543)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
immune system phenotype J:103485
Rab7tm1.1Ale/Rab7tm1.1Ale
Tg(Cd4-cre)1Cwi/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
abnormal T cell morphology J:211733
abnormal T cell physiology J:211733
abnormal T cell subpopulation ratio J:211733
decreased CD4-positive, alpha-beta T cell number J:211733
decreased CD8-positive, alpha-beta T cell number J:211733
decreased T cell number J:211733
decreased T cell proliferation J:211733
Rab7btm1Ciphe/Rab7btm1Ciphe
Tg(Itgax-cre)1-1Reiz/0

(involves: C57BL/6N * CBA)
abnormal dendritic cell migration J:321707
Rab11atm1.1Ngao/Rab11atm1.1Ngao
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6J * SJL)
abnormal cytokine secretion J:215917
increased interleukin-1 beta secretion J:215917
increased interleukin-6 secretion J:215917
intestinal inflammation J:215917
Rab11atm1.1Ngao/Rab11atm1.1Ngao
Tg(Vil1-cre/ERT2)23Syr/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
increased interleukin-6 secretion J:215917
Rab11fip2em1(IMPC)Mbp/Rab11fip2em1(IMPC)Mbp
(C57BL/6NCrl-Rab11fip2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Rab13tm1.1Ktg/Rab13tm1.1Ktg
(involves: C57BL/6)
abnormal leukocyte adhesion J:259093
abnormal T cell physiology J:259093
decreased lymphocyte cell number J:259093
decreased lymphocyte chemotaxis J:259093
immune system phenotype J:259093
impaired leukocyte migration J:259093
lymphoid hypoplasia J:259093
small inguinal lymph nodes J:259093
small spleen J:259093
Rab19tm1b(EUCOMM)Hmgu/Rab19tm1b(EUCOMM)Hmgu
(C57BL/6N-Rab19tm1b(EUCOMM)Hmgu/Ics)
decreased large unstained cell number J:211773
increased eosinophil cell number J:211773
Rab20tm1a(EUCOMM)Hmgu/Rab20tm1a(EUCOMM)Hmgu
(involves: C57BL/6N)
abnormal macrophage physiology J:243883
Rab26em1Guwa/Rab26em1Guwa
(Not Specified)
increased susceptibility to endotoxin shock J:306921
Rab27aash/Rab27aash
(involves: C3H/HeDiSn)
abnormal NK cell degranulation J:111253
decreased cytotoxic T cell cytolysis J:111253, J:67600
immune system phenotype J:111253
impaired natural killer cell mediated cytotoxicity J:111253
Rab27aash/Rab27aash
(B6.C3Sn-Rab27aash)
abnormal cytotoxic T cell physiology J:193137
decreased cytotoxic T cell cytolysis J:193137
decreased leukocyte cell number J:193137
decreased neutrophil cell number J:193137
decreased NK cell degranulation J:193137
increased circulating interferon-gamma level J:193137
increased circulating interleukin-1 beta level J:193137
increased circulating interleukin-6 level J:193137
increased circulating tumor necrosis factor level J:193137
increased susceptibility to Riboviria infection J:193137
Rab27acct/Rab27acct
(C57BL/6-Rab27acct)
abnormal neutrophil physiology J:114299
immune system phenotype J:114299
Rab32tm1c(KOMP)Wtsi/Rab32tm1c(KOMP)Wtsi
Tg(Itgax-cre)1-1Reiz/0

(involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * CBA)
abnormal cytokine secretion J:267497
increased neutrophil cell number J:267497
increased susceptibility to bacterial infection J:231298, J:267497
increased susceptibility to colitis induced morbidity/mortality J:267497
increased susceptibility to induced colitis J:267497
Rab33bem1Rmr/Rab33b+
(involves: C57BL/6)
abnormal osteoclast differentiation J:338833
abnormal osteoclast morphology J:338833
increased osteoclast cell number J:338833
Rab33bem1Rmr/Rab33bem1Rmr
(involves: C57BL/6)
abnormal osteoclast morphology J:338833
increased osteoclast cell number J:338833
Rab39bem1(IMPC)Tcp/Y
(C57BL/6NCrl-Rab39bem1(IMPC)Tcp/Tcp)
decreased spleen weight J:211773
Rab43tm1.2Kmm/Rab43tm1.2Kmm
(B6.129S(C)-Rab43tm1.2Kmm)
abnormal dendritic cell antigen presentation J:101977
Rab44em1Rbrc/Rab44em1Rbrc
(Not Specified)
abnormal mast cell physiology J:304506
increased susceptibility to type I hypersensitivity reaction J:304506
Rabgap1tm1b(EUCOMM)Hmgu/Rabgap1tm1b(EUCOMM)Hmgu
(C57BL/6N-Rabgap1tm1b(EUCOMM)Hmgu/Ieg)
enlarged spleen J:211773
small spleen J:211773
Rabgef1tm1Glli/Rabgef1tm1Glli
(either: (involves: 129P2/OlaHsd * 129S/SvEv) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal inflammatory response J:91790
abnormal mast cell morphology J:91790
chronic inflammation J:91790
cutaneous mastocytosis J:91790
increased IgE level J:91790
increased interleukin-6 secretion J:91790
increased tumor necrosis factor secretion J:91790
Rabgef1tm2Glli/Rabgef1tm2Glli
(WBB6F1)
increased interleukin-6 secretion J:91790
increased tumor necrosis factor secretion J:91790
Rabggtagm/Rabggta+
(C57BL/6J-Rabggtagm)
decreased cytotoxic T cell cytolysis J:67600
Rabggtagm/Rabggtagm
(C57BL/6J-Rabggtagm)
decreased cytotoxic T cell cytolysis J:67600
Rabggtatm1.1(KOMP)Vlcg/Rabggta+
(C57BL/6N-Rabggtatm1.1(KOMP)Vlcg/Nju)
decreased neutrophil cell number J:211773
Rabl3xm/Rabl3em1Btlr
(C57BL/6J-Rabl3xm Rabl3em1Btlr)
decreased leukocyte cell number J:287198
decreased lymphocyte cell number J:287198
spleen hypoplasia J:287198
thymus hypoplasia J:287198
Rabl3xm/Rabl3xm
(C57BL/6J-Rabl3xm)
abnormal T cell morphology J:287198
abnormal T cell number J:287198
Rac1em1(IMPC)Mbp/Rac1+
(C57BL/6N-Rac1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Rac1tm1Djk/Rac1tm1.1Djk
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
decreased acute inflammation J:83457
decreased leukocyte cell number J:83457
decreased neutrophil cell number J:83457
impaired neutrophil chemotaxis J:83457
impaired neutrophil recruitment J:83457
Rac2em1Shl/Rac2+
(involves: C57BL/6)
abnormal neutrophil morphology J:276213
decreased alpha-beta T cell number J:276213
decreased CD4-positive, alpha-beta T cell number J:276213
decreased CD8-positive, alpha-beta T cell number J:276213
decreased leukocyte cell number J:276213
decreased lymphocyte cell number J:276213
decreased T cell number J:276213
increased neutrophil cell number J:276213
Rac2m1Btlr/Rac2+
(C57BL/6J-Rac2m1Btlr)
decreased IgM level J:221478
impaired humoral immune response J:221478
Rac2m1Btlr/Rac2m1Btlr
(C57BL/6J-Rac2m1Btlr)
decreased IgM level J:221478
impaired humoral immune response J:221478
Rac2M2Btlr/Rac2+
(C57BL/6J-Rac2M2Btlr)
decreased B-1 B cell number J:231801
decreased B-1a cell number J:231801
increased B-1b cell number J:231801
Rac2M2Btlr/Rac2M2Btlr
(C57BL/6J-Rac2M2Btlr)
decreased B-1 B cell number J:231801
decreased B-1a cell number J:231801
increased B-1b cell number J:231801
Rac2m3Btlr/Rac2+
(C57BL/6J-Rac2m3Btlr)
decreased B-1a cell number J:236680
increased B-1 B cell number J:236680
Rac2m3Btlr/Rac2m3Btlr
(C57BL/6J-Rac2m3Btlr)
decreased B cell number J:236680
decreased B-1a cell number J:236680
decreased IgM level J:236680
decreased response to antigen J:236680
increased B-1b cell number J:236680
increased neutrophil cell number J:236680
Rac2M4Btlr/Rac2+
(C57BL/6J-Rac2M4Btlr)
abnormal cytotoxic T cell physiology J:255273
decreased alpha-beta T cell number J:255273
decreased CD4-positive, alpha-beta T cell number J:255273
decreased CD8-positive, alpha-beta T cell number J:255273
decreased CD8-positive, naive alpha-beta T cell number J:255273
decreased IgG level J:255273
decreased IgM level J:255273
impaired humoral immune response J:255273
impaired natural killer cell mediated cytotoxicity J:255273
increased alpha-beta T cell number J:255273
increased CD8-positive, alpha-beta T cell number J:255273
increased central memory CD8 positive, alpha-beta T cell number J:255273
increased effector memory CD4-positive, alpha-beta T cell number J:255273
increased effector memory CD8-positive, alpha-beta T cell number J:255273
increased IgM level J:255273
Rac2M4Btlr/Rac2M4Btlr
(C57BL/6J-Rac2M4Btlr)
abnormal cytotoxic T cell physiology J:255273
decreased alpha-beta T cell number J:255273
decreased CD4-positive, alpha-beta T cell number J:255273
decreased CD8-positive, alpha-beta T cell number J:255273
decreased CD8-positive, naive alpha-beta T cell number J:255273
decreased IgE level J:255273
decreased IgG level J:255273
decreased IgM level J:255273
impaired humoral immune response J:255273
impaired natural killer cell mediated cytotoxicity J:255273
increased alpha-beta T cell number J:255273
increased CD8-positive, alpha-beta T cell number J:255273
increased central memory CD4-positive, alpha-beta T cell number J:255273
increased central memory CD8 positive, alpha-beta T cell number J:255273
increased effector memory CD4-positive, alpha-beta T cell number J:255273
increased effector memory CD8-positive, alpha-beta T cell number J:255273
Rac2M5Btlr/Rac2+
(C57BL/6J-Rac2M5Btlr)
increased CD8-positive, alpha-beta T cell number J:255283
Rac2M5Btlr/Rac2M5Btlr
(C57BL/6J-Rac2M5Btlr)
decreased B-1a cell number J:255283
increased B-1b cell number J:255283
increased CD8-positive, alpha-beta T cell number J:255283
Rac2tm1Mddw/Rac2tm1Mddw
(involves: 129S/SvEv * C57BL/6)
abnormal granulocyte differentiation J:53362
abnormal neutrophil physiology J:53362
decreased leukocyte cell number J:53362
decreased neutrophil cell number J:53362
decreased T cell proliferation J:119437
impaired neutrophil chemotaxis J:53362
increased leukocyte cell number J:53362
increased neutrophil cell number J:53362
increased susceptibility to bacterial infection J:53362
Rac2tm1Mddw/Rac2tm1Mddw
(involves: 129S/SvEv)
abnormal neutrophil physiology J:131305
Rac2tm1Mddw/Rac2tm1Mddw
(B6.129S-Rac2tm1Mddw)
abnormal neutrophil physiology J:83457
Rac2tm1Mddw/Rac2tm1Mddw
Tg(TcrAND)53Hed/0

(involves: 129S/SvEv * C57BL/6 * SJL)
abnormal T cell activation J:119437
decreased circulating interleukin-2 level J:119437
decreased T cell proliferation J:119437
Racgap1tm1Mahi/Racgap1tm1Mahi
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal B cell differentiation J:137760
abnormal myelopoiesis J:137760
decreased pro-B cell number J:137760
decreased transitional stage B cell number J:137760
Rad1tm1.1Jcbs/Rad1tm1.1Jcbs
(involves: 129P2/OlaHsd * 129S4/SvJaeSor)
immune system phenotype J:169551
Rad21tm1.1Mmk/Rad21tm1.1Mmk
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:175827
abnormal CD4-positive, alpha-beta T cell physiology J:175827
abnormal T cell differentiation J:175827
decreased CD4-positive, alpha-beta T cell number J:175827
decreased CD8-positive, alpha-beta T cell number J:175827
decreased double-positive T cell number J:175827
Rad23btm1Gvh/Rad23btm1Gvh
(involves: 129P2/OlaHsd * C57BL/6)
blepharitis J:74288
conjunctivitis J:74288
Rad50tm1Flv/Rad50tm1Flv
(involves: 129S6/SvEvTac * C57BL/6)
abnormal T-helper 2 physiology J:94870
decreased interleukin-4 secretion J:94870
decreased interleukin-5 secretion J:94870
decreased interleukin-13 secretion J:94870
Rad50tm2.1Flv/Rad50tm2.1Flv
(B6.129S6-Rad50tm2.1Flv)
decreased interleukin-4 secretion J:196154
decreased interleukin-5 secretion J:196154
decreased interleukin-13 secretion J:196154
Rad50tm2.1Flv/Rad50tm2.2Flv
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:165055
abnormal T-helper 1 physiology J:165055
abnormal T-helper 2 physiology J:165055
decreased IgE level J:165055
decreased inflammatory response J:165055
decreased interferon-gamma secretion J:165055
decreased interleukin-4 secretion J:165055
decreased interleukin-5 secretion J:165055
decreased interleukin-13 secretion J:165055
immune system phenotype J:165055
Rad50tm2Jpt/Rad50tm2Jpt
(either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6))
abnormal immune system cell morphology J:78820
abnormal immune system organ morphology J:78820
abnormal spleen morphology J:78820
abnormal thymus morphology J:78820
decreased B cell number J:78820
decreased immature B cell number J:78820
decreased pre-B cell number J:78820
decreased T cell number J:78820
increased late pro-B cell number J:78820
increased macrophage cell number J:78820
spleen hyperplasia J:78820
Rad50tm2Jpt/Rad50tm2Jpt
(involves: 129S7/SvEvBrd * C57BL/6)
decreased double-negative T cell number J:103922
decreased macrophage cell number J:103922
decreased pro-B cell number J:103922
Rad50tm2Jpt/Rad50tm2Jpt
Smc1atm1Mbk/Smc1atm1Mbk

(involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6)
abnormal pro-B cell morphology J:103922
decreased double-negative T cell number J:103922
decreased macrophage cell number J:103922
Rad50tm2Jpt/Rad50tm2Jpt
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129S2/SvPas * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6)
immune system phenotype J:78820
Rad50tm3.1Flv/Rad50tm3.1Flv
(B6.129S6-Rad50tm3.1Flv)
decreased interleukin-4 secretion J:196154
decreased interleukin-5 secretion J:196154
decreased interleukin-13 secretion J:196154
Rad50tm4.1Flv/Rad50tm4.1Flv
(B6.129S6-Rad50tm4.1Flv)
decreased interleukin-5 secretion J:196154
decreased interleukin-13 secretion J:196154
increased interleukin-4 secretion J:196154
increased interleukin-5 secretion J:196154
increased interleukin-13 secretion J:196154
Rad52tm1Aps/Rad52tm1Aps
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:50357
Rad54ltm1Jhjh/Rad54ltm1Jhjh
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:39642
Rad54ltm1Jhjh/Rad54ltm1Jhjh
(involves: 129P2/OlaHsd)
immune system phenotype J:47993
Radilem1(IMPC)Tcp/Radilem1(IMPC)Tcp
(C57BL/6NCrl-Radilem1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Raet1dem1Dhr/Raet1dem1Dhr
Raet1eem1Dhr/Raet1eem1Dhr

(involves: C57BL/6)
increased natural killer cell mediated cytotoxicity J:221188
Raf1tm1.1Bgn/Raf1+
(involves: 129S6/SvEvTac * C57BL/6NCr)
enlarged spleen J:172034
increased leukocyte cell number J:172034
increased monocyte cell number J:172034
increased neutrophil cell number J:172034
Rag1/Rag2tm1Mnz/Rag1/Rag2tm1Mnz
(involves: 129P2/OlaHsd * C57BL/6)
abnormal double-negative T cell morphology J:90487
abnormal double-positive T cell morphology J:90487
abnormal T cell morphology J:90487
decreased T cell number J:90487
Rag1/Rag2tm1Mnz/Rag1/Rag2tm1Mnz
(involves: 129P2/OlaHsd * C57BL/6)
abnormal double-negative T cell morphology J:90487
abnormal double-positive T cell morphology J:90487
abnormal T cell morphology J:90487
decreased T cell number J:90487
Rag1coln/Rag1coln
(C57BL/6JAnu-Rag1coln/AnuApb)
absent B cells J:104190
absent T cells J:104190
Rag1em2Mvw/Rag1em2Mvw
(A/J-Rag1em2Mvw/MvwJ)
absent B cells J:332675
absent T cells J:332675
arrested B cell differentiation J:332675
arrested T cell differentiation J:332675
Rag1em3Mvw/Rag1em3Mvw
(129S1/SvImJ-Rag1em3Mvw/Mvw)
absent B cells J:332675
absent T cells J:332675
arrested B cell differentiation J:332675
arrested T cell differentiation J:332675
Rag1m1Anu/Rag1m1Anu
(C57BL/6NCrlAnu-Rag1m1Anu)
decreased lymphocyte cell number J:104190
Rag1m1Btlr/Rag1m1Btlr
(C57BL/6J-Rag1m1Btlr)
absent late pro-B cells J:150635
decreased CD4-positive, alpha-beta T cell number J:150635
decreased CD8-positive, alpha-beta T cell number J:150635
Rag1m2Btlr/Rag1m2Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
decreased B cell number J:185495
decreased IgG level J:185495
decreased IgM level J:185495
decreased T cell number J:185495
Rag1m3Btlr/Rag1m3Btlr
(C57BL/6J-Rag1m3Btlr)
increased central memory CD8 positive, alpha-beta T cell number J:272858
Rag1m4Btlr/Rag1m4Btlr
(C57BL/6J-Rag1m4Btlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:272094
abnormal T cell differentiation J:272094
decreased B cell number J:272094
decreased CD8-positive, naive alpha-beta T cell number J:272094
increased alpha-beta T cell number J:272094
increased CD8-positive, alpha-beta T cell number J:272094
increased central memory CD8 positive, alpha-beta T cell number J:272094
Rag1tm1(cre)Thr/?
Shcbp1tm1c(EUCOMM)Wtsi/Shcbp1tm1c(EUCOMM)Wtsi

(involves: C57BL/6N)
immune system phenotype J:212898
Rag1tm1(cre)Thr/Rag1tm1(cre)Thr
(Not Specified)
abnormal lymphopoiesis J:86869
absent lymphocyte J:86869
Rag1tm1(GFP)Imku/?
Zfp335blt/Zfp335blt

(involves: C57BL/6 * CBA)
abnormal CD4-positive T cell differentiation J:214793
Rag1tm1(GFP)Imku/Rag1tm1(GFP)Imku
(involves: C57BL/6 * CBA)
abnormal immunoglobulin V(D)J recombination J:79416
Rag1tm1.1Sadu/Rag1tm1.1Sadu
(involves: BALB/c)
arrested B cell differentiation J:155473
Rag1tm1.1Sadu/Rag1tm1.1Sadu
Trdctm1Mal/Trdctm1Mal
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
absent gamma-delta T cells J:187400
decreased gamma-delta T cell number J:187400
increased gamma-delta T cell number J:187400
small thymus J:187400
Rag1tm1Bal/Rag1tm1Bal
Tg(TcraTcrb)1100Mjb/?

(involves: 129S4/SvJae * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:133645
decreased CD4-positive, alpha-beta T cell number J:133645
increased CD8-positive, alpha-beta T cell number J:133645
Rag1tm1Bal/Rag1tm1Bal
Tnfrsf1atm1.1Gkl/Tnfrsf1atm1.1Gkl

(involves: 129/Sv * C57BL/6)
liver inflammation J:92470
Rag1tm1Bal/Rag1tm1Bal
Vav1tm2Tyb/Vav1tm2Tyb

(involves: 129S4/SvJae * 129S8/SvEv)
arrested T cell differentiation J:113270
Rag1tm1Bal/Rag1tm1Bal
Vav1tm2Tyb/Vav1tm2Tyb
Tg(TcrAND)53Hed/0

(involves: 129S4/SvJae * 129S8/SvEv * C57BL/6 * SJL)
decreased CD4-positive, alpha-beta T cell number J:113270
Rag1tm1Fwa/Rag1tm1Fwa
(involves: 129)
abnormal B cell differentiation J:86464
abnormal T cell differentiation J:86464
decreased B cell number J:86464
increased double-negative T cell number J:86464
thymus hypoplasia J:86464
Rag1tm1Jsek/Rag1+
(involves: 129S6/SvEvTac)
abnormal B cell differentiation J:146912
abnormal immunoglobulin heavy chain V(D)J recombination J:146912
abnormal T cell differentiation J:146912
abnormal T cell receptor beta chain V(D)J recombination J:146912
decreased double-positive T cell number J:146912
Rag1tm1Jsek/Rag1tm1Jsek
(involves: 129S6/SvEvTac)
abnormal immunoglobulin heavy chain V(D)J recombination J:146912
abnormal immunoglobulin level J:146912
abnormal lymphopoiesis J:146912
abnormal T cell receptor beta chain V(D)J recombination J:146912
abnormal T cell receptor V(D)J recombination J:146912
absent immature B cells J:146912
absent mature B cells J:146912
arrested B cell differentiation J:146912
arrested T cell differentiation J:146912
decreased CD4-positive, alpha-beta T cell number J:146912
decreased CD8-positive, alpha-beta T cell number J:146912
decreased double-positive T cell number J:146912
decreased gamma-delta T cell number J:146912
increased double-negative T cell number J:146912
increased pro-B cell number J:146912
thymus hypoplasia J:146912
Rag1tm1Mom/Rag1tm1Mom
(involves: 129S7/SvEvBrd * CD-1)
abnormal B cell differentiation J:1934
abnormal immunoglobulin V(D)J recombination J:1934
abnormal inguinal lymph node morphology J:1934
abnormal T cell differentiation J:1934
abnormal T cell morphology J:1934
abnormal T cell receptor V(D)J recombination J:1934
absent mature B cells J:1934
decreased IgM level J:1934
spleen hypoplasia J:1934
thymus hypoplasia J:1934
Rag1tm1Mom/Rag1tm1Mom
(B6.129S7-Rag1tm1Mom)
decreased IgM level J:78613
decreased immunoglobulin level J:111828
dermatitis J:111828
ear inflammation J:111828
increased eosinophil cell number J:111828
Rag1tm1Mom/Rag1tm1Mom
(involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD)
decreased lymphocyte cell number J:111874
small thymus J:111874
Rag1tm1Mom/Rag1tm1Mom
(NOD.129S7(B6)-Rag1tm1Mom)
abnormal level of surface class II molecules J:109843
decreased CD4-positive, alpha-beta T cell number J:109843
decreased CD8-positive, alpha-beta T cell number J:109843
decreased immunoglobulin level J:109843
decreased mature B cell number J:109843
impaired natural killer cell mediated cytotoxicity J:109843
increased granulocyte number J:109843
increased immature B cell number J:109843
increased macrophage cell number J:109843
increased NK cell number J:109843
spleen hypoplasia J:109843
Rag1tm1Mom/Rag1tm1Mom
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal lymphatic vessel morphology J:119344
abnormal response to infection J:119344
autoimmune response J:138466
decreased neutrophil cell number J:119344
decreased susceptibility to induced colitis J:194587
Rag1tm1Mom/Rag1tm1Mom
(involves: 129S7/SvEvBrd)
abnormal double-negative T cell morphology J:112990
abnormal thymus epithelium morphology J:125864
decreased inflammatory response J:94420
Rag1tm1Mom/Rag1tm1Mom
Prf1tm1Sdz/Prf1tm1Sdz

(NOD.Cg-Rag1tm1Mom Prf1tm1Sdz/Sz)
abnormal level of surface class II molecules J:109843
abnormal lymph node cortex morphology J:109843
abnormal response to transplant J:109843
abnormal spleen white pulp morphology J:109843
abnormal thymus cortex morphology J:109843
decreased CD4-positive, alpha-beta T cell number J:109843
decreased CD8-positive, alpha-beta T cell number J:109843
decreased immunoglobulin level J:109843
decreased mature B cell number J:109843
impaired natural killer cell mediated cytotoxicity J:109843
increased granulocyte number J:109843
increased immature B cell number J:109843
increased macrophage cell number J:109843
increased NK cell number J:109843
spleen hypoplasia J:109843
thymus hypoplasia J:109843
Rag1tm1Mom/Rag1tm1Mom
Rasa3scat/Rasa3scat

(involves: 129S7/SvEvBrd * BALB/cBy)
abnormal immune system morphology J:186485
Rag1tm1Mom/Rag1tm1Mom
Sh3bp2tm1Bjro/Sh3bp2tm1Bjro

(involves: 129S4/SvJae * 129S7/SvEvBrd * BALB/cJ * C57BL/6J)
abnormal osteoclast differentiation J:117880
increased circulating tumor necrosis factor level J:117880
increased inflammatory response J:117880
Rag1tm1Mom/Rag1tm1Mom
Slc46a2tm1Moki/Slc46a2+
Tg(TcraB12,TcrbB12)1Rest/0

(involves: 129 * C57BL/6)
arrested T cell differentiation J:140121
decreased double-positive T cell number J:140121
increased T cell apoptosis J:140121
thymus hypoplasia J:140121
Rag1tm1Mom/Rag1tm1Mom
Tg(CAG-Lyn*)#Paau/0

(involves: 129S7/SvEvBrd * C57BL/6)
decreased inflammatory response J:151886
Rag1tm1Mom/Rag1tm1Mom
Tg(Lck-Akt1*E40K)E-3Pnt/0

(involves: 129S7/SvEvBrd * C3H/He * C57BL/6)
increased double-positive T cell number J:135903
increased thymocyte number J:135903
Rag1tm1Mom/Rag1tm1Mom
Tg(LPV-TAg1135)11Tvd/0

(involves: 129/Sv * C57BL/6 * DBA/2)
abnormal T cell receptor V(D)J recombination J:47667
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra,Tcrb)HRCAll/0

(B6.Cg-Rag1tm1Mom Tg(Tcra,Tcrb)HRCAll)
abnormal T cell differentiation J:131347
abnormal T cell subpopulation ratio J:131347
absent CD4-positive, alpha-beta T cells J:131347
increased CD8-positive, alpha-beta T cell number J:131347
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0

(NOD.Cg-Rag1tm1Mom Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs/Dvs)
increased susceptibility to autoimmune diabetes J:94192
Rag1tm1Mom/Rag1tm1Mom
Tg(TcraBDC12-4.1)10Jos/0
Tg(TcrbBDC12-4.1)82Gse/0

(involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD)
decreased CD4-positive, alpha-beta T cell number J:111874
decreased lymphocyte cell number J:111874
decreased thymus weight J:111874
increased double-positive T cell number J:111874
increased susceptibility to autoimmune diabetes J:111874
Rag1tm1Mom/Rag1tm1Mom
Tnftm2Gkl/Tnf+

(involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6)
rheumatoid arthritis J:54056
small intestinal inflammation J:54056
Rag1tm1Mom/Rag1tm1Mom
Tnfrsf25tm1Mjo/Tnfrsf25tm1Mjo

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
abnormal T cell differentiation J:84536
Rag1tm1Mom/Rag1tm1Mom
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
decreased osteoclast cell number J:294030
Rag1tm1Mom/Rag1tm1Mom
Tyrobptm1.1Viv/Tyrobptm1.1Viv

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/10)
abnormal osteoclast physiology J:129304
Rag1tm1Mom/Rag1tm1Mom
Vtcn1tm1Lpc/Vtcn1tm1Lpc

(involves: 129S/SvEvBrd * 129S7/SvEvBrd * C57BL/6)
abnormal neutrophil differentiation J:145712
decreased susceptibility to bacterial infection J:145712
decreased susceptibility to bacterial infection induced morbidity/mortality J:145712
increased neutrophil cell number J:145712
increased spleen weight J:145712
Rag2m1Btlr/Rag2m1Btlr
(C57BL/6J-Rag2m1Btlr)
abnormal humoral immune response J:203045
decreased B cell number J:203045
decreased CD4-positive, alpha-beta T cell number J:203045
decreased IgG level J:203045
decreased IgM level J:203045
Rag2tm1.1Cgn/Rag2tm1.1Cgn
(C57BL/6-Rag2tm1.1Cgn)
arrested B cell differentiation J:72214
arrested T cell differentiation J:72214
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Tg(HLA-DR2)#Lfug/0
Tg(TCROb.1A12)#Lfug/0

(involves: C57BL/6 * DBA/2)
autoimmune response J:134764
CNS inflammation J:134764
Rag2tm1.1Cgn/Rag2tm1.1Cgn
Trex1tm1Tld/Trex1tm1Tld

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:181257
Rag2tm1.1Desi/Rag2tm1.1Desi
(involves: 129X1/SvJ * C57BL/6)
abnormal immunoglobulin V(D)J recombination J:168974
Rag2tm1.1Mss/Rag2tm1.1Mss
(involves: 129S6/SvEvTac)
abnormal lymphopoiesis J:171970
abnormal pre-B cell morphology J:171970
decreased pre-B cell number J:171970
increased DN3 thymocyte number J:171970
Rag2tm1Avla/Rag2tm1Avla
(involves: 129/Sv * C57BL/6)
abnormal B cell physiology J:122108
abnormal immune system cell morphology J:122108
abnormal immune system organ morphology J:122108
abnormal lymph node morphology J:122108
abnormal lymphocyte physiology J:122108
abnormal spleen morphology J:122108
abnormal thymus morphology J:122108
absent Hassall's corpuscle J:122108
absent Peyer's patches J:122108
arrested B cell differentiation J:122108
arrested T cell differentiation J:122108
colitis J:122108
decreased double-positive T cell number J:122108
decreased IgA level J:122108
decreased IgG level J:122108
decreased lymphocyte cell number J:122108
decreased NK T cell number J:122108
decreased spleen white pulp amount J:122108
decreased T cell proliferation J:122108
erythroderma J:122108
small cervical lymph nodes J:122108
small inguinal lymph nodes J:122108
small lymph nodes J:122108
small spleen J:122108
Rag2tm1Cgn/Rag2tm1.1Cgn
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal B cell activation J:72214
absent immature B cells J:72214
absent pre-B cells J:72214
arrested B cell differentiation J:72214
arrested T cell differentiation J:72214
decreased follicular B cell number J:72214
decreased marginal zone B cell number J:72214
decreased mature B cell number J:72214
increased plasma cell number J:72214
Rag2tm1Cgn/Rag2tm1Cgn
Xrcc4tm1Fwa/Xrcc4tm2Fwa
Tg(Cr2-cre)3Cgn/?

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6)
abnormal class switch recombination J:150339
Rag2tm1Fwa/Rag2tm1Fwa
(involves: 129S/SvEv * MF1)
abnormal effector T cell morphology J:1935
abnormal immunoglobulin V(D)J recombination J:1935
abnormal spleen morphology J:1935
abnormal T cell receptor V(D)J recombination J:1935
absent mature B cells J:1935
arrested B cell differentiation J:1935
arrested T cell differentiation J:1935
decreased CD4-positive, alpha-beta T cell number J:1935
decreased CD8-positive, alpha-beta T cell number J:1935
decreased double-positive T cell number J:1935
decreased IgM level J:1935
increased granulocyte number J:1935
increased macrophage cell number J:1935
increased natural killer cell mediated cytotoxicity J:1935
increased susceptibility to infection J:1935
lymph node hypoplasia J:1935
spleen hypoplasia J:1935
thymus hypoplasia J:1935
Rag2tm1Fwa/Rag2tm1Fwa
(involves: 129S/SvEv)
abnormal chemokine secretion J:140483
abnormal interferon secretion J:140483
abnormal macrophage physiology J:140483
abnormal response to transplant J:116136
abnormal T-helper 1 physiology J:116136
colitis J:116136
decreased susceptibility to bacterial infection induced morbidity/mortality J:140483
decreased thymocyte number J:114561
increased susceptibility to bacterial infection J:140483
lung inflammation J:140483
Rag2tm1Fwa/Rag2tm1Fwa
(involves: 129S/SvEv * C57BL/6)
abnormal B cell morphology J:81133
arrested T cell differentiation J:91542
decreased double-negative T cell number J:81133, J:91542
decreased susceptibility to parasitic infection J:64283
decreased susceptibility to type IV hypersensitivity reaction J:165513
increased double-negative T cell number J:91542
Rag2tm1Fwa/Rag2tm1Fwa
Cd47tm1Fpl/Cd47tm1Fpl
Il2rgtm1Cgn/Y

(involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6)
absent peripheral lymph nodes J:203904
decreased CD4-positive, alpha-beta T cell number J:203904
decreased lymphocyte cell number J:203904
decreased susceptibility to graft versus host disease J:203904
increased activated T cell number J:203904
increased CD8-positive, alpha-beta T cell number J:203904
increased susceptibility to Retroviridae infection J:203904
Rag2tm1Fwa/Rag2tm1Fwa
Rr299391tm1.1Fwa/Rr299391tm1.1Fwa

(involves: 129P2/OlaHsd * 129S/SvEv)
abnormal T cell receptor delta chain V(D)J recombination J:149413
Rag2tm1Fwa/Rag2tm1Fwa
Sos1tm1.1Les/Sos1tm1.1Les
Tg(Lck-cre)1Cwi/0

(involves: 129S/SvEv * C57BL/6)
abnormal T cell differentiation J:174536
decreased T cell proliferation J:174536
Rag2tm1Fwa/Rag2tm1Fwa
Tbatatm1Faf/Tbatatm1Faf

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
abnormal T cell differentiation J:166065
increased thymocyte number J:166065
Rag2tm1Fwa/Rag2tm1Fwa
Tbx21tm1Glm/Tbx21tm1Glm

(involves: 129S/SvEv * 129S6/SvEvTac)
colitis J:141481
increased tumor necrosis factor secretion J:141481
large intestinal inflammation J:141481
Rag2tm1Fwa/Rag2tm1Fwa
TcraLn3Jae/Tcra+
TcrbLn3Jae/Tcrb+

(involves: 129S/SvEv * 129S4/SvJae * C57BL/6)
abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
decreased CD4-positive, alpha-beta T cell number J:143006
increased CD8-positive, alpha-beta T cell number J:143006
Rag2tm1Fwa/Rag2tm1Fwa
TcrbLn3Jae/Tcrb+

(involves: 129S/SvEv * 129S4/SvJae * C57BL/6)
abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
decreased CD4-positive, alpha-beta T cell number J:143006
increased double-positive T cell number J:143006
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-NPM/ALK)N1Ingh/0

(involves: 129S/SvEv * C57BL/6 * Swiss Webster)
increased DN3 thymocyte number J:235890
Rag2tm1Fwa/Rag2tm1Fwa
Tg(DO11.10)10Dlo/0

(involves: 129S/SvEv * BALB/c * C3H * C57BL/6)
immune system phenotype J:110446
Rag2tm1Fwa/Rag2tm1Fwa
Tg(EmuSR-tTa)83Bop/0
Tg(tetO-Nfatct1*)1Grc/0

(involves: 129S/SvEv * C57BL/6J * CBA/J * FVB/N)
abnormal double-positive T cell morphology J:141917
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Igh-Pim1)1Brn/0

(involves: 129S/SvEv * C57BL/6LiA * CBA)
decreased thymocyte number J:114561
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Lck-Akt1*)M-1Pnt/0

(involves: 129S/SvEv * C3H/He * C57BL/6)
absent CD4-positive, alpha-beta T cells J:135903
absent CD8-positive, alpha-beta T cells J:135903
increased double-positive T cell number J:135903
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra5CC7,Tcrb5CC7)IWep/?
Themis5AT161/Themis5AT161

(involves: 129S/SvEv * C57BL/6)
arrested T cell differentiation J:151076
increased double-positive T cell number J:151076
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr/0

(involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * DBA/2)
abnormal CD4-positive T cell differentiation J:125548
abnormal positive T cell selection J:125548
decreased CD4-positive, alpha-beta T cell number J:125548
increased double-positive T cell number J:125548
thymus hyperplasia J:125548
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraCN.B1,TcrbCN.B1)SM1Jen/0

(involves: 129S/SvEv * C57BL/6)
increased susceptibility to bacterial infection induced morbidity/mortality J:162539
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129S/SvEv * C57BL/6J * DBA/2J)
abnormal CD8-positive, alpha beta T cell morphology J:125259
abnormal CD8-positive, alpha-beta T cell physiology J:125259
abnormal cytotoxic T cell physiology J:66565
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
Themis5AT161/Themis5AT161

(involves: 129S/SvEv * C57BL/6 * DBA/2)
decreased single-positive T cell number J:151076
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrHEL3A9)1Mmd/0

(involves: 129S/SvEv * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal double-positive T cell morphology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
abnormal thymus cell ratio J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcrHEL3A9)1Mmd/0
Tg(TLK2mHEL)2Ccg/0

(involves: 129S/SvEv * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal CD4-positive, alpha-beta T cell physiology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
decreased double-positive T cell number J:78309
thyroid gland inflammation J:78309
Rag2tm1Fwa/Rag2tm1Fwa
Wdr1rede/Wdr1rede

(involves: 129S/SvEv * C57BL/6)
abnormal immune system physiology J:134092
Rag2tm1Fwa/Rag2tm1Mao
(involves: 129S/SvEv * C57BL/6)
abnormal B cell number J:81837
abnormal gamma-delta T cell differentiation J:81837
arrested B cell differentiation J:81837
arrested T cell differentiation J:81837
decreased double-negative T cell number J:81837
decreased immature B cell number J:81837
decreased mature B cell number J:81837
decreased pre-B cell number J:81837
increased immature B cell number J:81837
thymus hypoplasia J:81837
Rag2tm1Libo/Rag2tm1Libo
(involves: 129S6/SvEvTac * C57BL/6 * FVB/N)
abnormal B cell differentiation J:84563
abnormal B cell physiology J:84563
decreased B cell number J:84563
decreased monocyte cell number J:84563
decreased pre-B cell number J:84563
Rag2tm1Mao/Rag2tm1Mao
(involves: 129S6/SvEvTac * C57BL/6)
abnormal immune system cell morphology J:81837
Rag2tm1Mao/Rag2tm1Mao
(involves: 129 * C57BL/6)
abnormal B cell number J:81837
abnormal gamma-delta T cell differentiation J:81837
arrested B cell differentiation J:81837
arrested T cell differentiation J:81837
decreased double-negative T cell number J:81837
decreased immature B cell number J:81837
decreased mature B cell number J:81837
decreased pre-B cell number J:81837
increased immature B cell number J:81837
thymus hypoplasia J:81837
Rag2tm1Tgi/Rag2tm1Tgi
(involves: 129S1/Sv * 129X1/SvJ)
abnormal Peyer's patch morphology J:113641
arrested B cell differentiation J:113641
arrested T cell differentiation J:113641
decreased B cell number J:113641
decreased double-positive T cell number J:113641
decreased thymocyte number J:113641
Ralatm1a(EUCOMM)Wtsi/Ralatm1a(EUCOMM)Wtsi
(C57BL/6N-Ralatm1a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Ralbtm1a(EUCOMM)Wtsi/Ralbtm1a(EUCOMM)Wtsi
(C57BL/6N-Ralbtm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Ramp1tm1.1Tsuj/Ramp1tm1.1Tsuj
(C.129S2-Ramp1tm1.1Tsuj)
abnormal chemokine secretion J:125974
abnormal cytokine secretion J:125974
increased circulating interferon-gamma level J:125974
increased circulating interleukin-6 level J:125974
increased circulating tumor necrosis factor level J:125974
Ramp1tm1b(EUCOMM)Wtsi/Ramp1tm1b(EUCOMM)Wtsi
(C57BL/6N-Ramp1tm1b(EUCOMM)Wtsi/H)
increased basophil cell number J:211773
Ramp2tm1Kmca/Ramp2tm1Kmca
(involves: 129S6/SvEvTac * C57BL/6)
abnormal lymph organ development J:130930
abnormal lymphatic vessel morphology J:130930
Ranbp17em1(IMPC)Tcp/Ranbp17em1(IMPC)Tcp
(C57BL/6N-Ranbp17em1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
Rap1atm1Laaq/Rap1atm1Laaq
(either: B6.Cg-Rap1atm1Laaq or (involves: C57BL/6))
abnormal leukocyte migration J:140471
abnormal macrophage physiology J:140471
abnormal neutrophil physiology J:140471
immune system phenotype J:140471
Rap1atm1Tze/Rap1atm1Tze
(involves: 129P2/OlaHsd * C57BL/6)
abnormal leukocyte adhesion J:144145
decreased interleukin-2 secretion J:144145
decreased T cell proliferation J:144145
Rap1gap2m1Anu/Rap1gap2m1Anu
(C57BL/6NCrlAnu-Rap1gap2m1Anu)
immune system phenotype J:104190
Rap1gapem1(IMPC)H/Rap1gapem1(IMPC)H
(C57BL/6NTac-Rap1gapem1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Rap1gds1tm1Ytk/Rap1gds1tm1Ytk
(involves: 129X1/SvJ * C57BL/6 * DBA)
abnormal thymus morphology J:62244
decreased thymocyte number J:62244
increased thymocyte apoptosis J:62244
small thymus J:62244
Rapgef2tm1.1Hous/Rapgef2tm1.1Hous
Tg(Cd4-cre)1Cwi/0

(involves: 129S1/Sv * C57BL/6 * CBA)
immune system phenotype J:165879
Rapgef2tm1.1Hous/Rapgef2tm1.1Hous
Tg(Cdh5-cre)7Mlia/0

(involves: 129S1/Sv * FVB/N)
immune system phenotype J:165879
Rapgef2tm1.1Hous/Rapgef2tm1.1Hous
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * C57BL/6 * CBA)
immune system phenotype J:165879
Rapgef2tm1.1Hous/Rapgef2tm1.1Hous
Tg(VAV1-cre)1Graf/0

(involves: 129S1/Sv)
immune system phenotype J:165879
Rapgef3tm1Skc/Rapgef3tm1Skc
(Not Specified)
insulitis J:201171
Rapgef6tm1.1Tkat/Rapgef6tm1.1Tkat
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:126164
Rapgef6tm1.1Tkat/Rapgef6tm1.1Tkat
(involves: 129P2/OlaHsd)
enlarged spleen J:218581
Raph1tm1.2Fbg/Raph1tm1.2Fbg
(involves: 129S4/SvJae * C57BL/6)
abnormal cytokine level J:238262
increased inflammatory response J:238262
increased susceptibility to bacterial infection J:238262
large intestinal inflammation J:238262
Raratm1.1Ybe/Raratm1.1Ybe
(involves: C57BL/6N)
abnormal lymphopoiesis J:207485
Raratm1Ipc/Raratm1Ipc
Rarbtm1Ipc/Rarbtm1Ipc

(involves: 129S2/SvPas)
persistent cervical thymus J:21034
Raratm1Ipc/Raratm1Ipc
Rarbtm1Mma/Rarbtm1Mma

(involves: 129S2/SvPas * C57BL/6)
abnormal thymus morphology J:43344
persistent cervical thymus J:43344
Raratm1Ipc/Raratm1Ipc
Rargtm1Ipc/Rargtm1Ipc

(involves: 129S2/SvPas)
persistent cervical thymus J:21034
Raratm1Ipc/Raratm1Ipc
Rargtm2Ipc/Rargtm2Ipc

(involves: 129S2/SvPas)
ectopic thymus J:42773
Rarres1tm1.2Mhl/Rarres1tm1.2Mhl
(involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss)
abnormal B cell activation J:324270
abnormal B cell differentiation J:324270
abnormal B cell physiology J:324270
abnormal plasma cell differentiation J:324270
decreased B cell apoptosis J:324270
decreased spleen germinal center number J:324270
increased B cell proliferation J:324270
Rarres2tm1Yktk/Rarres2tm1Yktk
(B6.Cg-Rarres2tm1Yktk)
decreased macrophage cell number J:206120
Rasa1tm1Wid/Rasa1tm1Wid
(involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6N)
increased susceptibility to induced colitis J:189241
Rasa3hlb381/Rasa3hlb381
(C57BL/6J-Rasa3hlb381/J)
decreased leukocyte cell number J:301035, J:221899
enlarged spleen J:221899
increased spleen weight J:301035
Rasa3scat/Rasa3scat
(involves: BALB/cBy)
abnormal spleen morphology J:186485
decreased B cell number J:186485
decreased CD4-positive, alpha-beta T cell number J:186485
decreased CD8-positive, alpha-beta T cell number J:186485
decreased leukocyte cell number J:186485
decreased T cell number J:186485
enlarged spleen J:186485
increased spleen red pulp amount J:186485
pale spleen J:186485
Rasa3scat/Rasa3scat
(involves: BALB/cBy * BALB/cByJ)
decreased leukocyte cell number J:301035
increased spleen weight J:301035
Rasa3tm1.1Llp/Rasa3tm1.1Llp
Tg(Mx1-cre)1Cgn/?

(involves: 129S1/SvImJ * C57BL/6J * CBA/J)
bone marrow failure J:301035
decreased leukocyte cell number J:301035
increased spleen weight J:301035
Rasa4tm1Ywh/Rasa4tm1Ywh
(B6.129S6-Rasa4tm1Ywh)
impaired macrophage phagocytosis J:100455
increased susceptibility to bacterial infection J:100455
Rasal3tm1.1Fuj/Rasal3tm1.1Fuj
(involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj)
decreased circulating interferon-gamma level J:229641
decreased circulating interleukin-4 level J:229641
decreased interferon-gamma secretion J:229641
decreased interleukin-4 secretion J:229641
decreased NK T cell number J:229641
increased granulocyte number J:229641
Rasal3tm1b(EUCOMM)Hmgu/Rasal3tm1b(EUCOMM)Hmgu
(C57BL/6N-Rasal3tm1b(EUCOMM)Hmgu/Orl)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Rasgrf2tm1Esn/Rasgrf2tm1Esn
(involves: 129S1/Sv * C57BL/10 * C57BR/cd)
decreased interleukin-2 secretion J:128985
decreased tumor necrosis factor secretion J:128985
Rasgrf2tm1Esn/Rasgrf2tm1Esn
Vav1tm1Tyb/Vav1tm1Tyb

(involves: 129S1/Sv * 129S2/SvPas * C57BL/10 * C57BR/cd)
abnormal T cell physiology J:128985
decreased interleukin-2 secretion J:128985
decreased T cell proliferation J:128985
decreased tumor necrosis factor secretion J:128985
Rasgrp1lag/Rasgrp1lag
(involves: 129 * C57BL/6)
abnormal lymph node morphology J:85189
abnormal positive T cell selection J:85189
abnormal T cell physiology J:85189
decreased T cell proliferation J:85189
enlarged lymph nodes J:85189
enlarged spleen J:85189
glomerulonephritis J:85189
increased B cell number J:85189
increased IgG level J:85189
increased susceptibility to systemic lupus erythematosus J:85189
increased T cell number J:85189
Rasgrp1m1Anu/Rasgrp1+
(involves: C57BL/6JSfdAnu * CBA/J)
increased anti-nuclear antigen antibody level J:207898
Rasgrp1m1Anu/Rasgrp1m1Anu
(C57BL/6JSfdAnu-Rasgrp1m1Anu)
abnormal T cell differentiation J:104190
autoimmune response J:104190
Rasgrp1m1Anu/Rasgrp1m1Anu
(involves: C57BL/6JSfdAnu * CBA/J)
abnormal CD4-positive, alpha beta T cell morphology J:207898
immune system phenotype J:207898
increased anti-nuclear antigen antibody level J:207898
increased effector memory CD4-positive, alpha-beta T cell number J:207898
Rasgrp1m1Btlr/Rasgrp1m1Btlr
(C57BL/6J-Rasgrp1m1Btlr)
abnormal humoral immune response J:265163
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:265163
decreased CD8-positive, naive alpha-beta T cell number J:265163
decreased IgM level J:265163
increased CD8-positive, alpha-beta memory T cell number J:265163
increased effector memory CD4-positive, alpha-beta T cell number J:265163
increased IgA level J:265163
increased IgE level J:265163
increased IgM level J:265163
increased NK cell number J:265163
Rasgrp1m2Anu/Rasgrp1m2Anu
(C57BL/6NCrlAnu-Rasgrp1m2Anu)
immune system phenotype J:104190
Rasgrp1m2Btlr/Rasgrp1m2Btlr
(C57BL/6J-Rasgrp1m2Btlr)
decreased CD4-positive, alpha-beta T cell number J:265163
decreased CD8-positive, alpha-beta T cell number J:265163
decreased CD8-positive, naive alpha-beta T cell number J:265163
decreased single-positive T cell number J:265163
decreased T cell number J:265163
increased central memory CD4-positive, alpha-beta T cell number J:265163
increased central memory CD8 positive, alpha-beta T cell number J:265163
increased effector memory CD4-positive, alpha-beta T cell number J:265163
increased effector memory CD8-positive, alpha-beta T cell number J:265163
increased NK cell number J:265163
Rasgrp1m3Btlr/Rasgrp1m3Btlr
(C57BL/6J-Rasgrp1m3Btlr)
decreased CD4-positive, alpha-beta T cell number J:265255
decreased CD8-positive, alpha-beta T cell number J:265255
decreased CD8-positive, naive alpha-beta T cell number J:265255
decreased single-positive T cell number J:265255
decreased T cell number J:265255
increased B cell number J:265255
increased B-1b cell number J:265255
increased central memory CD8 positive, alpha-beta T cell number J:265255
increased effector memory CD4-positive, alpha-beta T cell number J:265255
increased effector memory CD8-positive, alpha-beta T cell number J:265255
increased IgM level J:265255
increased neutrophil cell number J:265255
increased NK cell number J:265255
Rasgrp1M4Btlr/Rasgrp1M4Btlr
(C57BL/6J-Rasgrp1M4Btlr)
abnormal T cell morphology J:267490
Rasgrp1m5Btlr/Rasgrp1m5Btlr
(C57BL/6J-Rasgrp1m5Btlr)
increased NK cell number J:272846
Rasgrp1tm1.1Wz/Rasgrp1tm1.1Wz
(B6.Cg-Rasgrp1tm1.1Wz)
abnormal CD4-positive T cell differentiation J:225109
abnormal CD8-positive, alpha-beta T cell differentiation J:225109
abnormal immune system cell morphology J:225109
abnormal immune system organ morphology J:225109
abnormal immune system physiology J:225109
abnormal immunoglobulin level J:225109
abnormal T cell differentiation J:225109
decreased single-positive T cell number J:225109
decreased T cell proliferation J:225109
enlarged spleen J:225109
immune system phenotype J:225109
increased autoantibody level J:225109
increased CD4-positive, alpha-beta memory T cell number J:225109
increased IgE level J:225109
increased IgG1 level J:225109
increased single-positive T cell number J:225109
increased spleen weight J:225109
Rasgrp1tm1.1Wz/Rasgrp1tm1.1Wz
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: C57BL/6J * DBA/2J)
decreased single-positive T cell number J:225109
increased double-positive T cell number J:225109
Rasgrp1tm1.1Wz/Rasgrp1tm1.1Wz
Tg(TcraTcrb)425Cbn/?

(involves: C57BL/6 * BALB/c)
abnormal CD4-positive T cell differentiation J:225109
Rasgrp1tm1Jstn/Rasgrp1tm1Jstn
(involves: 129P3/J * C57BL/6J)
abnormal humoral immune response J:108677
decreased B cell number J:108677
decreased thymocyte number J:108677
enlarged spleen J:108677
increased immunoglobulin level J:108677
increased plasma cell number J:108677
Rasgrp1tm1Jstn/Rasgrp1tm1Jstn
(involves: 129P3/J)
abnormal CD4-positive, alpha beta T cell morphology J:207898
abnormal double-positive T cell morphology J:207898
decreased CD4-positive, alpha-beta T cell number J:207898
decreased CD8-positive, alpha-beta T cell number J:207898
Rasgrp1tm1Jstn/Rasgrp1tm1Jstn
Rasgrp3tm1Jstn/Rasgrp3tm1Jstn

(involves: 129P3/J * C57BL/6J)
abnormal humoral immune response J:108677
decreased B cell number J:108677
decreased plasma cell number J:108677
Rasgrp2tm1Amg/Rasgrp2tm1Amg
(Not Specified)
abnormal neutrophil physiology J:122618
impaired neutrophil recruitment J:122618
Rasgrp3em1(IMPC)Wtsi/Rasgrp3em1(IMPC)Wtsi
(C57BL/6N-Rasgrp3em1(IMPC)Wtsi/Wtsi)
increased CD8-positive, naive alpha-beta T cell number J:211773
Rasgrp3tm1Jstn/Rasgrp3tm1Jstn
(involves: 129P3/J * C57BL/6J)
abnormal humoral immune response J:108677
decreased B cell number J:108677
decreased IgG1 level J:108677
decreased IgG2a level J:108677
decreased IgG level J:108677
Rasgrp4tm1(cre)Rls/Rasgrp4tm1(cre)Rls
(C57BL/6-Rasgrp4tm1(cre)Rls)
decreased susceptibility to induced arthritis J:186519
decreased susceptibility to induced colitis J:186519
Rasgrp4tm1a(KOMP)Lste/Rasgrp4tm1a(KOMP)Lste
(involves: C57BL/6)
abnormal neutrophil physiology J:186412
impaired neutrophil chemotaxis J:186412
Rasgrp4tm1d(KOMP)Lste/Rasgrp4tm1d(KOMP)Lste
(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6)
abnormal neutrophil physiology J:186412
impaired neutrophil chemotaxis J:186412
Rassf1tm1.2Brd/Rassf1tm1.2Brd
(involves: 129S7/SvEvBrd * C57BL/6)
immune system phenotype J:101369
Rassf2tm1Dlim/Rassf2tm1Dlim
(B6.Cg-Rassf2tm1Dlim)
abnormal myeloid leukocyte morphology J:181952
abnormal osteoclast differentiation J:181952
abnormal spleen red pulp morphology J:181952
abnormal thymus epithelium morphology J:181952
decreased B cell number J:181952
decreased CD4-positive, alpha-beta T cell number J:181952
decreased CD8-positive, alpha-beta T cell number J:181952
decreased leukocyte cell number J:181952
decreased osteoclast cell number J:181952
decreased spleen weight J:181952
decreased T cell number J:181952
decreased thymus weight J:181952
spleen hypoplasia J:181952
thymus hypoplasia J:181952
Rassf5tm1Kina/Rassf5+
(involves: C57BL/6 * CBA * ICR)
lymphoid hypoplasia J:92670
Rassf5tm1Kina/Rassf5tm1Kina
(involves: C57BL/6 * CBA * ICR)
abnormal B cell differentiation J:92670
abnormal dendritic cell physiology J:92670
abnormal leukocyte migration J:92670
abnormal lymph node cell ratio J:92670
abnormal lymph node cortex morphology J:92670
abnormal spleen red pulp morphology J:92670
abnormal thymus cell ratio J:92670
abnormal thymus corticomedullary boundary morphology J:92670
abnormal thymus medulla morphology J:92670
decreased thymocyte number J:92670
spleen hypoplasia J:92670
Rassf5tm1Kina/Rassf5tm1Kina
(B6.Cg-Rassf5tm1Kina)
abnormal lymphocyte physiology J:168749
enlarged lymph nodes J:168749
enlarged spleen J:168749
glomerulonephritis J:168749
increased anti-double stranded DNA antibody level J:168749
increased B cell number J:168749
increased B cell proliferation J:168749
increased IgG level J:168749
increased memory T cell number J:168749
increased plasma cell number J:168749
increased T cell number J:168749
increased T cell proliferation J:168749
Raver1em1(IMPC)Hmgu/Raver1em1(IMPC)Hmgu
(C57BL/6NCrl-Raver1em1(IMPC)Hmgu/Ieg)
increased spleen weight J:211773
Rb1tm1Dwg/Rb1tm1Dwg
(involves: 129/Sv * C57BL/6)
abnormal macrophage morphology J:105548
Rb1tm1Mlh/Rb1tm1Mlh
(either: 129P2/OlaHsd-Rb1tm1Mlh or (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlaHsd * FVB/N))
abnormal myelopoiesis J:2498
Rb1tm1Tyj/Rb1tm1Tyj
(involves: 129S2/SvPas)
abnormal macrophage differentiation J:105548
Rb1tm2Mlh/Rb1tm2Mlh
(either: 129P2/OlaHsd-Rb1tm2Mlh or (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlaHsd * FVB/N))
abnormal myelopoiesis J:2498
Rb1cc1tm1.1Guan/Rb1cc1tm1.1Guan
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
immune system phenotype J:235399
Rb1cc1tm1.1Guan/Rb1cc1tm1.1Guan
Tg(BEST1-cre)1Jdun/0

(involves: 129P2/OlaHsd * C57BL/6)
microgliosis J:282249
Rb1cc1tm1.1Guan/Rb1cc1tm1.1Guan
Tg(Tek-cre)12Flv/0

(B6.Cg-Rb1cc1tm1.1Guan Tg(Tek-cre)12Flv)
abnormal myelopoiesis J:167258
increased neutrophil cell number J:167258
Rbbp4em1(IMPC)Mbp/Rbbp4+
(C57BL/6NCrl-Rbbp4em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Rbbp8tm1Whl/Rbbp8tm1.1Thl
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor)
immune system phenotype J:194603
Rbl1tm1Mru/Rbl1tm1Mru
(involves: 129S4/SvJae * BALB/cJ)
abnormal inflammatory response J:51060
abnormal spleen red pulp morphology J:51060
Rbm3tm1Ttg/Rbm3tm1Ttg
(involves: 129P2/OlaHsd)
immune system phenotype J:174947
Rbm4tm1a(EUCOMM)Hmgu/Rbm4+
(C57BL/6N-Rbm4tm1a(EUCOMM)Hmgu/Cnrm)
decreased IgG2b level J:165965
Rbm7em1Aki/Rbm7em1Aki
(B6.Cg-Rbm7em1Aki)
decreased monocyte cell number J:288329
Rbm10em1(IMPC)Mbp/Rbm10+
(C57BL/6NCrl-Rbm10em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Rbm15tm1Dgg/Rbm15tm1.1Dgg
Tg(Mx1-cre)1Cgn/0

(involves: 129/Sv * C57BL/6 * CBA * FVB/N)
abnormal B cell differentiation J:120321
decreased B cell number J:120321
decreased pre-B cell number J:120321
increased spleen red pulp amount J:120321
Rbm15tm1Swm/Rbm15tm1Swm
Tg(Mx1-cre)1Cgn/0

(involves: 129X1/SvJ * C57BL/6 * CBA)
decreased leukocyte cell number J:152262
decreased lymphocyte cell number J:152262
decreased neutrophil cell number J:152262
increased spleen red pulp amount J:152262
Rbm20em1(IMPC)Mbp/Rbm20em1(IMPC)Mbp
(C57BL/6N-Rbm20em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Rbm22em1(IMPC)Mbp/Rbm22+
(C57BL/6NCrl-Rbm22em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
Rbm38tm1.1Xch/Rbm38tm1.1Xch
(involves: C57BL/6 * FVB/N)
enlarged spleen J:216929
increased spleen white pulp amount J:216929
Rbm38tm1.1Xch/Rbm38tm1.1Xch
Trp53tm1Tyj/Trp53+

(involves: 129S2/SvPas * C57BL/6 * FVB/N)
abnormal spleen B cell follicle morphology J:216929
Rbp1tm1Ipc/Rbp1tm1Ipc
(involves: 129S2/SvPas)
increased granulocyte number J:67762
increased neutrophil cell number J:67762
Rbpjtm1Hon/Rbpjtm1Hon
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:76240
Rbpjtm1Hon/Rbpjtm1Hon
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA)
abnormal T-helper 2 cell differentiation J:90018
Rbpjtm1Hon/Rbpjtm1Hon
Tg(Itgax-cre)1-1Reiz/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal cytokine secretion J:125869
decreased dendritic cell number J:125869
Rbpjtm1Hon/Rbpjtm1Hon
Tg(Lck-cre)19Hhan/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA)
abnormal CD4-positive helper T cell morphology J:168475
abnormal immune system physiology J:168475
abnormal regulatory T cell physiology J:168475
immune system phenotype J:168475
increased macrophage cell number J:168475
increased single-positive T cell number J:168475
increased splenocyte number J:168475
increased T cell number J:168475
increased T cell proliferation J:168475
Rbpjtm1Hon/Rbpjtm1Hon
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal B cell differentiation J:99747
abnormal lymphopoiesis J:99747
arrested T cell differentiation J:125869, J:99747
decreased dendritic cell number J:125869
decreased double-positive T cell number J:99747
decreased follicular dendritic cell number J:125869
decreased marginal zone B cell number J:76240, J:99747
decreased single-positive T cell number J:99747
decreased thymocyte number J:99747
increased B cell number J:125869, J:99747
increased double-negative T cell number J:99747
increased follicular B cell number J:99747
increased macrophage cell number J:125869
increased monocyte cell number J:125869
increased plasmacytoid dendritic cell number J:125869
small thymus J:99747
Rbpjtm1Kyo/Rbpj+
(involves: 129S2/SvPas * CD-1)
aortic valve inflammation J:187551
Rbpjtm1Kyo/Rbpjtm1Kyo
(involves: 129S2/SvPas)
abnormal humoral immune response J:123631
abnormal response to infection J:123631
decreased interleukin-4 secretion J:123631
Rc3h1Gt(CC0753)Wtsi/Rc3h1Gt(CC0753)Wtsi
(B6.129P2-Rc3h1Gt(CC0753)Wtsi)
chronic liver inflammation J:199407
ileum inflammation J:199407
intestinal inflammation J:199407
Rc3h1san/Rc3h1+
(involves: C57BL/6JSfdAnu)
abnormal lymph node germinal center morphology J:189087
abnormal lymph node morphology J:189087
abnormal T follicular helper cell physiology J:189087
enlarged lymph nodes J:189087
increased IgG level J:189087
increased spleen weight J:189087
increased T follicular helper cell number J:189087
Rc3h1san/Rc3h1san
(either: C57BL/6JSfdAnu-Rc3h1san/Anu or (involves: C57BL/6JSfdAnu * CBA/Ca))
abnormal T cell differentiation J:98938
enlarged lymph nodes J:98938
glomerulonephritis J:98938
increased anti-double stranded DNA antibody level J:98938
increased anti-nuclear antigen antibody level J:98938
liver inflammation J:98938
Rc3h1san/Rc3h1san
(involves: C57BL/6JSfdAnu)
abnormal effector T cell morphology J:199407
abnormal intraepithelial T cell number J:199407
cecum inflammation J:199407
chronic liver inflammation J:199407
colitis J:199407
enlarged spleen J:199407
granulomatous inflammation J:199407
ileum inflammation J:199407
increased activated T cell number J:199407
increased CD4-positive, alpha-beta T cell number J:199407
increased circulating tumor necrosis factor level J:196137
increased T cell proliferation J:199407
lymphoid hyperplasia J:199407
small intestinal inflammation J:199407
Rc3h1san/Rc3h1san
Rc3h2tm1.2Cgv/Rc3h2tm1.2Cgv

(involves: C57BL/6 * C57BL/6JSfdAnu)
increased circulating tumor necrosis factor level J:196137
increased inflammatory response J:196137
increased susceptibility to bacterial infection J:196137
increased T follicular helper cell number J:196137
kidney inflammation J:196137
Rc3h1tm1.1Mass/Rc3h1tm1.1Mass
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * NZB * SJL)
abnormal effector T cell morphology J:177784
enlarged spleen J:177784
increased B cell number J:177784
increased eosinophil cell number J:177784
increased regulatory T cell number J:177784
increased spleen weight J:177784
Rc3h1tm1.1Mass/Rc3h1tm1.1Mass
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca * NZB * SJL)
abnormal B cell differentiation J:177784
abnormal effector T cell morphology J:177784
abnormal germinal center B cell physiology J:177784
abnormal spleen B cell follicle morphology J:177784
decreased B cell number J:177784
decreased IgA level J:177784
decreased IgG1 level J:177784
decreased IgG3 level J:177784
decreased immature B cell number J:177784
enlarged spleen J:177784
immune system phenotype J:177784
increased eosinophil cell number J:177784
increased IgG2b level J:177784
increased macrophage cell number J:177784
increased regulatory T cell number J:177784
increased spleen weight J:177784
increased splenocyte number J:177784
spleen hyperplasia J:177784
Rc3h1tm1.1Mass/Rc3h1tm1.1Mass
Rc3h2tm1c(KOMP)Wtsi/Rc3h2tm1c(KOMP)Wtsi
Tg(Cd4-cre)1Cwi/?

(involves: C57BL/6N * DBA/2)
abnormal B cell number J:196136
abnormal immune system cell morphology J:196136
abnormal immune system organ morphology J:196136
abnormal immune system physiology J:196136
abnormal spleen B cell follicle morphology J:196136
abnormal spleen morphology J:196136
abnormal spleen periarteriolar lymphoid sheath morphology J:196136
decreased CD4-positive, alpha-beta T cell number J:196136
decreased CD8-positive, alpha-beta T cell number J:196136
decreased T cell number J:196136
enlarged lymph nodes J:196136
enlarged spleen J:196136
increased germinal center B cell number J:196136
increased T cell proliferation J:196136
increased T follicular helper cell number J:196136
Rc3h1tm1.1Mass/Rc3h1tm1.1Mass
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * NZB * SJL)
immune system phenotype J:177784
increased CD8-positive, alpha-beta T cell number J:177784
increased eosinophil cell number J:177784
increased macrophage cell number J:177784
Rc3h1tm1.2Cgv/Rc3h1san
(involves: C57BL/6 * C57BL/6JSfdAnu)
increased CD4-positive, alpha-beta T cell number J:196137
increased T follicular helper cell number J:196137
Rc3h1tm1.2Mass/Rc3h1tm1.2Mass
(involves: C57BL/6 * CBA * NZB * SJL)
abnormal thymus development J:177784
Rc3h1tm1.2Mass/Rc3h1tm1.2Mass
(involves: C57BL/6 * CBA * CD-1 * NZB * SJL)
abnormal effector T cell morphology J:177784
enlarged spleen J:177784
immune system phenotype J:177784
increased spleen weight J:177784
Rc3h2tm1.2Cgv/Rc3h2tm1.2Cgv
(involves: C57BL/6)
immune system phenotype J:196137
increased macrophage cytokine production J:196137
increased tumor necrosis factor secretion J:196137
Rc3h2tm1a(KOMP)Wtsi/Rc3h2tm1a(KOMP)Wtsi
(involves: C57BL/6N * NMRI)
immune system phenotype J:196136
Rc3h2tm1c(KOMP)Wtsi/Rc3h2tm1c(KOMP)Wtsi
Tg(Cd4-cre)1Cwi/?

(involves: C57BL/6N * DBA/2)
immune system phenotype J:196136
Rcan1tm1Fmc/Rcan1tm1Fmc
(involves: 129S4/SvJae)
abnormal T cell apoptosis J:85148
abnormal T-helper 1 physiology J:85148
decreased IgG2a level J:85148
decreased interferon-gamma secretion J:85148
decreased T cell proliferation J:85148
increased susceptibility to endotoxin shock J:152536
Rcan1tm1Jmol/Rcan1tm1Jmol
Rcan2tm1Jmol/Rcan2tm1Jmol

(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:109586
abnormal cytokine secretion J:109586
decreased T cell proliferation J:109586
Rcan1tm1Jmol/Rcan1tm1Jmol
Rcan2tm1Jmol/Rcan2tm1Jmol
Ppp3cbtm1Jmk/Ppp3cbtm1Jmk

(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:109586
abnormal CD4-positive, alpha-beta T cell physiology J:109586
abnormal CD8-positive, alpha beta T cell morphology J:109586
abnormal cytokine secretion J:109586
decreased T cell proliferation J:109586
Rcbtb2tm1.1Xyw/Rcbtb2+
(involves: C57BL/6 * CBA)
enlarged mesenteric lymph nodes J:282928
enlarged spleen J:282928
Rcbtb2tm1.1Xyw/Rcbtb2tm1.1Xyw
(involves: C57BL/6 * CBA)
abnormal splenocyte physiology J:282928
enlarged mesenteric lymph nodes J:282928
enlarged spleen J:282928
Rcc1ltm1a(EUCOMM)Hmgu/Rcc1l+
(Not Specified)
decreased IgG1 level J:165965
Rdh7tm1c(KOMP)Wtsi/Rdh7tm1c(KOMP)Wtsi
Tg(RARE-Hspa1b/lacZ)12Jrt/0
Tg(Vil1-cre)997Gum/0

(involves: C57BL/6J * C57BL/6N * CD-1 * SJL)
decreased lymphocyte cell number J:279231
decreased susceptibility to bacterial infection J:279231
immune system phenotype J:279231
Rdns/Rdns+
(C57BL/6J-Rdns/GrsrJ)
increased susceptibility to otitis media J:223062
Rdurem1Jiche/Rdurem1Jiche
(Not Specified)
increased circulating interleukin-1 level J:340209
increased circulating interleukin-6 level J:340209
increased susceptibility to viral infection J:340209
increased susceptibility to viral infection induced morbidity/mortality J:340209
Recql4tm1Abe/Recql4tm1Abe
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal thymus corticomedullary boundary morphology J:85574
decreased spleen white pulp amount J:85574
small thymus J:85574
Reg3bem1(IMPC)Mbp/Reg3bem1(IMPC)Mbp
(C57BL/6NCrl-Reg3bem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Reg3gtm1.1Lvh/Reg3gtm1.1Lvh
(B6.129-Reg3gtm1.1Lvh)
immune system phenotype J:177506
increased IgA level J:177506
increased T-helper 1 cell number J:177506
Reg3gtm1a(KOMP)Wtsi/Reg3gtm1a(KOMP)Wtsi
(C57BL/6-Reg3gtm1a(KOMP)Wtsi)
increased susceptibility to Orthomyxoviridae infection J:233979
RelM1Btlr/Rel+
(C57BL/6J-RelM1Btlr)
decreased IgE level J:236682
decreased IgG level J:236682
decreased IgM level J:236682
decreased response to antigen J:236682
increased CD4-positive, alpha-beta T cell number J:236682
increased T cell number J:236682
RelM1Btlr/RelM1Btlr
(C57BL/6J-RelM1Btlr)
decreased B-1 B cell number J:236682
decreased CD4-positive, alpha-beta T cell number J:236682
decreased CD8-positive, alpha-beta T cell number J:236682
decreased IgE level J:236682
decreased IgG level J:236682
decreased IgM level J:236682
decreased response to antigen J:236682
increased CD4-positive, alpha-beta T cell number J:236682
increased CD8-positive, alpha-beta T cell number J:236682
increased effector memory CD4-positive, alpha-beta T cell number J:236682
increased T cell number J:236682
RelM2Btlr/RelM2Btlr
(C57BL/6J-RelM2Btlr)
abnormal CD4-positive T cell differentiation J:272778
abnormal T cell differentiation J:272778
decreased alpha-beta T cell number J:272778
decreased B-1 B cell number J:272778
decreased CD4-positive, alpha-beta T cell number J:272778
decreased central memory CD4-positive, alpha-beta T cell number J:272778
decreased effector memory CD4-positive, alpha-beta T cell number J:272778
Relm3Btlr/Relm3Btlr
(C57BL/6J-Relm3Btlr)
decreased IgM level J:272801
impaired humoral immune response J:272801
Reltm1b(EUCOMM)Wtsi/Reltm1b(EUCOMM)Wtsi
(C57BL/6N-Reltm1b(EUCOMM)Wtsi/H)
decreased monocyte cell number J:211773
Reltm1Brv/Reltm1Brv
(involves: 129S1/Sv)
abnormal leukocyte physiology J:46911
abnormal macrophage morphology J:46911
abnormal macrophage physiology J:46911
abnormal spleen morphology J:46911
abnormal splenic cell ratio J:46911
abnormal T cell physiology J:46911
decreased IgG1 level J:46911
decreased IgG2b level J:46911
decreased IgG3 level J:46911
decreased IgG level J:46911
decreased spleen germinal center number J:46911
dermatitis J:46911
enlarged lymph nodes J:46911
enlarged spleen J:46911
impaired macrophage chemotaxis J:46911
increased IgA level J:46911
increased IgG2a level J:46911
increased IgM level J:46911
increased spleen B cell follicle size J:46911
increased susceptibility to bacterial infection J:46911
Reltm1Grd/Rel+
(involves: 129S1/Sv * C57BL/6)
abnormal humoral immune response J:28435
decreased B cell proliferation J:28435
Reltm1Grd/Reltm1Grd
(involves: 129S1/Sv * C57BL/6)
abnormal cytokine secretion J:37541, J:28435
abnormal humoral immune response J:28435
abnormal macrophage physiology J:37541
decreased B cell proliferation J:28435
decreased IgG1 level J:28435
decreased IgG2a level J:28435
decreased IgG2b level J:28435
decreased IgG3 level J:28435
decreased IgM level J:28435
decreased susceptibility to parasitic infection J:37541
decreased T cell proliferation J:28435
Reltm1Grd/Reltm1Grd
(involves: 129S1/Sv)
immune system phenotype J:113514
Reltm1Grd/Reltm1Grd
Relatm1Bal/Relatm1Bal

(B6.129S-Reltm1Grd Relatm1Bal)
abnormal monocyte differentiation J:111325
increased granulocyte number J:111325
Reltm1Hcl/Rel+
(involves: 129S4/SvJae * C57BL/6)
decreased T cell proliferation J:53513
Reltm1Hcl/Reltm1Hcl
(involves: 129S4/SvJae * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:79107, J:118907
abnormal cytokine secretion J:53513, J:79107
abnormal dendritic cell physiology J:118907
abnormal macrophage physiology J:118907
abnormal memory B cell number J:75621
abnormal professional antigen presenting cell physiology J:118907
abnormal T-helper 1 cell differentiation J:79107
decreased B cell proliferation J:75621
decreased cytotoxic T cell cytolysis J:53513
decreased IgE level J:58987
decreased susceptibility to autoimmune diabetes J:118907
decreased susceptibility to experimental autoimmune encephalomyelitis J:79107
decreased T cell proliferation J:53513, J:79107
immune system phenotype J:53513, J:118907, J:58987
increased eosinophil cell number J:58987
Relatm1Asba/Relatm1Asba
Tg(Vil1-cre)997Gum/0

(involves: 129 * C57BL/6J * SJL)
increased susceptibility to induced colitis J:131977
Relatm1Bal/Relatm1Bal
(involves: 129S4/SvJae)
decreased marginal zone B cell number J:65246
immune system phenotype J:113514
Relatm1Bal/Relatm1Bal
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx

(involves: 129S4/SvJae * C57BL/6)
abnormal spleen germinal center morphology J:60742
abnormal thymus morphology J:60742
decreased spleen white pulp amount J:60742
heart inflammation J:60742
liver inflammation J:60742
lung inflammation J:60742
Relatm1Mpa/Relatm1Mpa
Tg(Alb1-cre)7Gsc/0

(involves: FVB/N)
increased susceptibility to endotoxin shock J:137861
Relatm1Rsch/Relatm1Rsch
Ptf1atm1(cre)Hnak/?

(involves: C57BL/6)
abnormal interleukin level J:122194
abnormal tumor necrosis factor level J:122194
lung inflammation J:122194
pancreas inflammation J:122194
Relatm1Rsch/Relatm1Rsch
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal gamma-delta T cell morphology J:169863
Relatm1Rsch/Relatm1Rsch
Tg(Lck-cre)I57Jxm/0

(involves: ICR)
abnormal gamma-delta T cell morphology J:169863
decreased interleukin-17 secretion J:169863
immune system phenotype J:169863
increased susceptibility to bacterial infection J:169863
Relatm1Yuo/Relatm1Yuo
(involves: 129S/SvEv)
abnormal lymphocyte physiology J:63099
decreased B cell proliferation J:63099
decreased double-positive T cell number J:63099
decreased IgA level J:63099
decreased IgG1 level J:63099
decreased T cell proliferation J:63099
Relatm2.1Gho/Relatm2.1Gho
(involves: 129S6/SvEvTac * C57BL/6)
abnormal spleen morphology J:163663
increased inflammatory response J:163663
increased neutrophil cell number J:163663
interstitial pneumonia J:163663
liver inflammation J:163663
lung inflammation J:163663
myositis J:163663
Relatm2.1Gho/Relatm2.1Gho
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak

(involves: 129S2/SvPas * 129S6/SvEvTac)
increased incidence of corneal inflammation J:163663
liver inflammation J:163663
Relbshep/Relbshep
(A;C-Relbshep/GrsrJ)
liver inflammation J:171971
RelbTg(H2-K1/GH1)106Bri/Relb+
(involves: C57BL/6)
decreased NK T cell number J:120659
decreased Peyer's patch number J:120659
small Peyer's patches J:120659
RelbTg(H2-K1/GH1)106Bri/RelbTg(H2-K1/GH1)106Bri
(C57BL/6-RelbTg(H2-K1/GH1)106Bri)
abnormal antigen presentation J:23081
abnormal lymph node morphology J:76450
abnormal Peyer's patch morphology J:76450
absent thymus medulla J:23081, J:76450
decreased B cell number J:76450
decreased pre-B cell number J:76450
decreased T cell number J:76450
decreased T cell proliferation J:76450
enlarged spleen J:76450
glomerulonephritis J:76450
increased granulocyte number J:23081, J:76450
increased inflammatory response J:23081, J:76450
increased macrophage cell number J:23081, J:76450
liver inflammation J:76450
lung inflammation J:76450
skin inflammation J:76450
RelbTg(H2-K1/GH1)106Bri/RelbTg(H2-K1/GH1)106Bri
(involves: C57BL/6)
absent lymph nodes J:120659
absent Peyer's patches J:120659
decreased circulating interleukin-4 level J:120659
decreased NK T cell number J:120659
increased inflammatory response J:120659
Relbtm1.1Fwei/Relbtm1.1Fwei
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
immune system phenotype J:169863
Relbtm1.1Fwei/Relbtm1.1Fwei
Tg(Lck-cre)I57Jxm/0

(involves: ICR)
abnormal gamma-delta T cell morphology J:169863
decreased interleukin-17 secretion J:169863
immune system phenotype J:169863
increased susceptibility to bacterial infection J:169863
Relbtm1Brv/Relbtm1Brv
(involves: 129S2/SvPas * C57BL/6)
abnormal cell-mediated immunity J:22675
abnormal cytokine level J:40630
abnormal cytotoxic T cell physiology J:40630
abnormal humoral immune response J:40630
abnormal immune system organ morphology J:22675
abnormal immune system physiology J:22675, J:40630
abnormal immunoglobulin level J:40630
abnormal interferon level J:40630
abnormal interleukin level J:40630
abnormal lymph node morphology J:22675
abnormal macrophage physiology J:40630
abnormal mesenteric lymph node morphology J:22675
abnormal tumor necrosis factor level J:40630
decreased B cell proliferation J:40630
decreased dendritic cell number J:22675
decreased spleen white pulp amount J:22675
decreased susceptibility to type IV hypersensitivity reaction J:22675
decreased T cell number J:22675
epididymis inflammation J:22675
impaired neutrophil phagocytosis J:40630
increased IgE level J:40630
increased IgM level J:40630
increased spleen red pulp amount J:22675
increased spleen weight J:22675
increased susceptibility to bacterial infection J:40630
increased susceptibility to Riboviria infection J:40630
intestinal inflammation J:22675
liver inflammation J:22675
lung inflammation J:22675
myeloid hyperplasia J:22675
myositis J:22675
ovary inflammation J:22675
salivary gland inflammation J:22675
stomach inflammation J:22675
thymus atrophy J:22675
thymus hypoplasia J:22675
Relbtm1Brv/Relbtm1Brv
(either: (involves: 129S2/SvPas) or (involves: C57BL/6) or (involves: 129S2/SvPas * C57BL/6))
dermatitis J:63950
increased eosinophil cell number J:63950
lung inflammation J:63950
Relbtm1Brv/Relbtm1Brv
(involves: 129S2/SvPas)
abnormal gamma-delta T cell morphology J:169863
decreased dendritic cell number J:85808
spleen hyperplasia J:85808
Relnem1(IMPC)Mbp/Reln+
(C57BL/6N-Relnem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Relttm1Hlee/Relttm1Hlee
(Not Specified)
abnormal T cell morphology J:266480
immune system phenotype J:266480
increased T cell proliferation J:266480
Ren1tm1Tkh/Ren1tm1Tkh
(C57BL/6-Ren1tm1Tkh)
kidney inflammation J:110082
Rettm2.1Cos/Rettm2.1Cos
(involves: 129S1/Sv)
immune system phenotype J:195828
Rettm6.1Vpa/Rettm6.2Vpa
Tg(CD2-icre)4Kio/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/10 * CBA/Ca)
immune system phenotype J:195828
Retntm1Laz/Retntm1Laz
Tg(CD68-RETN)#Laz/?

(involves: 129S6/SvEvTac * C57BL/6)
white adipose tissue inflammation J:171262
Retnlatm1Mer/Retnlatm1Mer
(C57BL/6-Retnlatm1Mer)
abnormal chemokine secretion J:144784
decreased interleukin-5 secretion J:144784
decreased interleukin-6 secretion J:144927
decreased susceptibility to induced colitis J:144784, J:144927
impaired eosinophil recruitment J:144784
increased interleukin-10 secretion J:144927
Retnlatm1Mer/Retnlatm1Mer
(C.B6-Retnlatm1Mer)
decreased susceptibility to induced colitis J:144784, J:144927
Retnlatm1Mer/Retnlatm1Mer
(involves: C57BL/6)
abnormal macrophage physiology J:147863
abnormal T-helper 2 physiology J:147863
increased IgE level J:147863
increased IgG1 level J:147863
increased interleukin-4 secretion J:147863
increased interleukin-5 secretion J:147863
increased interleukin-13 secretion J:147863
Retnlbtm1Gdw/Retnlbtm1Gdw
(involves: 129S/SvEv * C57BL/6)
decreased inflammatory response J:114507
decreased susceptibility to induced colitis J:114507
Retnlbtm1Lex/Retnlbtm1Lex
(FVB.129S5-Retnlbtm1Lex)
abnormal CD4-positive, alpha-beta T cell physiology J:235058
decreased circulating interleukin-6 level J:235058
increased circulating interleukin-13 level J:235058
increased neutrophil cell number J:235058
liver inflammation J:235058
white adipose tissue inflammation J:235058
Retnlbtm1Mer/Retnlbtm1Mer
(involves: 129S1/Sv * C57BL/6)
decreased susceptibility to induced colitis J:141524
increased susceptibility to induced colitis J:141524
Retnlbtm1Mer/Retnlbtm1Mer
(involves: 129S1/Sv)
decreased IgG2a level J:141446
decreased interferon-gamma secretion J:141446
decreased susceptibility to parasitic infection J:141446
decreased tumor necrosis factor secretion J:141446
increased IgG1 level J:141446
Retreg2em2(IMPC)Ccpcz/Retreg2em2(IMPC)Ccpcz
(C57BL/6N-Retreg2em2(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased leukocyte cell number J:211773
Retreg3tm2b(EUCOMM)Wtsi/Retreg3tm2b(EUCOMM)Wtsi
(C57BL/6N-Fam134ctm2b(EUCOMM)Wtsi/Wtsi)
increased neutrophil cell number J:211773
Rev1tm1.1Jow/Rev1tm1.1Jow
(involves: C57BL/6)
abnormal somatic hypermutation frequency J:151700
immune system phenotype J:151700
Rev1tm1Ndew/Rev1tm1Ndew
(involves: 129P2/OlaHsd * C57BL/6)
abnormal somatic hypermutation frequency J:119176
immune system phenotype J:119176
lymphoid hypoplasia J:119176
Rev3ltm1.1Kunk/Rev3ltm1.1Kunk
(involves: C57BL/6)
abnormal somatic hypermutation frequency J:188723
immune system phenotype J:188723
Rev3ltm1Rsky/Rev3ltm1.1Rsky
Tg(Cr2-cre)3Cgn/?

(involves: C57BL/6)
abnormal class switch recombination J:146453
abnormal somatic hypermutation frequency J:146453
decreased B cell proliferation J:146453
decreased germinal center B cell number J:146453
decreased IgG1 level J:146453
Rexo2tm1b(EUCOMM)Wtsi/Rexo2+
(C57BL/6N-Rexo2tm1b(EUCOMM)Wtsi/H)
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Rfflem1(IMPC)Ccpcz/Rfflem1(IMPC)Ccpcz
(C57BL/6N-Rfflem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Rfkem1(IMPC)Mbp/Rfk+
(C57BL/6NCrl-Rfkem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Rfktm1.1Jcbr/Rfktm1.1Jcbr
Tg(Mx1-cre)1Cgn/?

(involves: C57BL/6 * CBA)
decreased macrophage nitric oxide production J:151999
Rft1tm1b(KOMP)Wtsi/Rft1+
(C57BL/6N-Rft1tm1b(KOMP)Wtsi/Bay)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased monocyte cell number J:211773
Rftn1tm1Ayos/Rftn1tm1Ayos
(B6.Cg-Rftn1tm1Ayos)
abnormal CD4-positive T cell differentiation J:150299
decreased IgG2a level J:150299
decreased interferon-gamma secretion J:150299
decreased interleukin-4 secretion J:150299
decreased interleukin-17 secretion J:150299
decreased splenocyte number J:150299
decreased susceptibility to experimental autoimmune encephalomyelitis J:150299
Rfx5tm1.1Ifo/Rfx5tm1.1Ifo
(involves: 129 * C57BL/6)
abnormal B lymphocyte antigen presentation J:67941
abnormal dendritic cell morphology J:67941
abnormal Kupffer cell morphology J:67941
abnormal level of surface class II molecules J:67941
abnormal MHC II cell surface expression on macrophages J:67941
abnormal thymus cortex morphology J:67941
decreased CD4-positive, alpha-beta T cell number J:67941
decreased IgG1 level J:67941
decreased IgM level J:67941
decreased single-positive T cell number J:67941
Rfx5tm1Ifo/Rfx5tm1.1Ifo
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * C57BL/6 * C.B-20)
abnormal MHC II cell surface expression on macrophages J:67924
Rfx5tm1Ifo/Rfx5tm1Ifo
(involves: 129P2/OlaHsd * C57BL/6J)
immune system phenotype J:282535
Rfx7tm1.1Ggaur/Rfx7tm1.1Ggaur
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
abnormal NK cell morphology J:282535
decreased NK cell number J:282535
small spleen J:282535
Rfx7tm1.1Ggaur/Rfx7tm1.1Ggaur
Ncr1tm1.1(icre)Viv/Ncr1+

(involves: C57BL/6)
abnormal NK cell physiology J:282535
decreased NK cell number J:282535
increased susceptibility to viral infection J:282535
Rfx7tm1.1Ggaur/Rfx7tm1.1Ggaur
Rptortm1.1Dmsa/Rptor+
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S/SvEv * C57BL/10 * CBA/Ca)
abnormal NK cell morphology J:282535
decreased NK cell number J:282535
small spleen J:282535
Rgcctm1Hrus/Rgcctm1Hrus
(involves: 129S6/SvEvTac * C57BL/6)
increased interleukin-2 secretion J:279555
increased T cell proliferation J:279555
Rgl1em1(IMPC)Mbp/Rgl1+
(C57BL/6N-Rgl1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Rgs1tm1Jhk/Rgs1tm1Jhk
(B6.129P2-Rgs1tm1Jhk)
abnormal B cell physiology J:90780
abnormal dendritic cell physiology J:89680
abnormal spleen germinal center morphology J:90780
decreased plasma cell number J:90780
increased immunoglobulin level J:90780
increased marginal zone B cell number J:90780
small Peyer's patches J:90780
Rgs2em1(IMPC)H/Rgs2+
(C57BL/6NTac-Rgs2em1(IMPC)H/H)
increased large unstained cell number J:211773
Rgs2em1(IMPC)H/Rgs2em1(IMPC)H
(C57BL/6NTac-Rgs2em1(IMPC)H/H)
enlarged spleen J:211773
Rgs2tm1Pngr/Rgs2tm1Pngr
(involves: C57BL/6J)
abnormal T cell proliferation J:77273
Rgs3tm1Ndul/Rgs3tm1Ndul
(B6.129-Rgs3tm1Ndul)
abnormal lymph node morphology J:210195
immune system phenotype J:210195
increased B cell number J:210195
increased CD4-positive, alpha-beta T cell number J:210195
increased CD8-positive, alpha-beta T cell number J:210195
increased susceptibility to type I hypersensitivity reaction J:210195
lung inflammation J:210195
Rgs4em1(IMPC)H/Rgs4em1(IMPC)H
(C57BL/6N-Rgs4em1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased spleen weight J:211773
Rgs4tm1Sdlk/Rgs4tm1Sdlk
Tg(Myh11-icre/ERT2)1Soff/?

(involves: FVB/N)
abnormal macrophage chemotaxis J:215588
Rgs5tm1Jhk/Rgs5tm1Jhk
(involves: 129S/SvEv * C57BL/6)
decreased lymphocyte cell number J:133897
Rgs10tm1Ypl/Rgs10tm1Ypl
(involves: 129S4/SvJae * C57BL/6J)
abnormal osteoclast differentiation J:123167
decreased osteoclast cell number J:123167
Rgs12tm1.1Syy/Rgs12tm1.1Syy
Tg(Mx1-cre)1Cgn/0

(involves: 129 * C57BL/6 * CBA)
decreased osteoclast cell number J:194057
Rgs13tm1.1Jhk/Rgs13tm1.1Jhk
(involves: C57BL/6)
abnormal B cell differentiation J:199530
abnormal humoral immune response J:199530
abnormal spleen morphology J:199530
decreased B cell number J:199530
immune system phenotype J:199530
increased B cell number J:199530
increased germinal center B cell number J:199530
increased IgA level J:199530
increased IgG1 level J:199530
increased IgG2b level J:199530
increased IgG2c level J:199530
increased IgG3 level J:199530
increased IgM level J:199530
increased spleen germinal center number J:199530
increased spleen germinal center size J:199530
Rgs13tm1Drue/Rgs13tm1Drue
(B6.129S-Rgs13tm1Drue)
abnormal mast cell physiology J:130209
increased susceptibility to type I hypersensitivity reaction J:130209
Rgs14tm1Lex/Rgs14tm1Lex
(involves: 129S5/SvEvBrd)
immune system phenotype J:103485
Rgs16tm1.1Drue/Rgs16tm1.1Drue
(involves: C57BL/6)
abnormal T-helper 1 physiology J:188966
abnormal T-helper 2 physiology J:188966
granulomatous inflammation J:188966
increased interleukin-5 secretion J:188966
increased interleukin-10 secretion J:188966
increased interleukin-13 secretion J:188966
increased susceptibility to parasitic infection J:188966
Rgsc14/Rgsc14+
(involves: C57BL/6JJcl * DBA/2JJcl)
increased leukocyte cell number J:133634
increased lymphocyte cell number J:133634
Rgsc15/Rgsc15+
(involves: C57BL/6JJcl * DBA/2JJcl)
increased leukocyte cell number J:133634
increased lymphocyte cell number J:133634
Rgsc17/Rgsc17+
(involves: C57BL/6JJcl * DBA/2JJcl)
decreased leukocyte cell number J:133634
decreased lymphocyte cell number J:133634
Rgsc844/Rgsc844+
(involves: C57BL/6JJcl * DBA/2JJcl)
abnormal neutrophil physiology J:133634
Rgsc1045/Rgsc1045+
(involves: C57BL/6JJcl * DBA/2JJcl)
abnormal neutrophil physiology J:133634
Rgsc1354/Rgsc1354+
(involves: C3H * C57BL/6JJcl)
abnormal neutrophil physiology J:133634
Rgsc1547/Rgsc1547+
(involves: C3H * C57BL/6JJcl)
increased susceptibility to otitis media J:133634
Rhagem1(IMPC)Ccpcz/Rhagem1(IMPC)Ccpcz
(C57BL/6NCrl-Rhagem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Rhbdd1tm1.1Mfm/Rhbdd1tm1.1Mfm
(involves: 129S/SvEv * C57BL/6J)
increased interleukin-6 secretion J:346394
increased susceptibility to endotoxin shock J:346394
increased tumor necrosis factor secretion J:346394
Rhbdd3tm1Caox/Rhbdd3tm1Caox
(B6.129S6-Rhbdd3tm1Caox)
abnormal dendritic cell physiology J:197348
immune system phenotype J:197348
increased circulating interferon-gamma level J:197348
increased circulating interleukin-6 level J:197348
increased interferon-gamma secretion J:197348
increased interleukin-6 secretion J:197348
increased natural killer cell mediated cytotoxicity J:197348
increased NK cell number J:197348
liver inflammation J:197348
Rhbdf1tm1.1Mfm/Rhbdf1tm1.1Mfm
(involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6J)
small spleen J:203951
small thymus J:203951
Rhbdf2cub/Rhbdf2cub
(B6.Cg-Rhbdf2cub)
white adipose tissue inflammation J:82006
Rhbdf2m1Btlr/Rhbdf2m1Btlr
(C57BL/6J-Rhbdf2m1Btlr)
decreased tumor necrosis factor secretion J:187583
Rhbdf2m1Btlr/Rhbdf2tm1a(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
decreased tumor necrosis factor secretion J:187583
Rhbdf2M2Btlr/Rhbdf2+
(C57BL/6J-Rhbdf2M2Btlr)
abnormal immune system physiology J:213194
Rhbdf2M3Btlr/Rhbdf2+
(C57BL/6J-Rhbdf2M3Btlr)
abnormal immune system physiology J:220064
Rhbdf2M3Btlr/Rhbdf2M3Btlr
(C57BL/6J-Rhbdf2M3Btlr)
abnormal immune system physiology J:220064
Rhbdf2tm1.1Mfm/Rhbdf2tm1.1Mfm
(B6.129S-Rhbdf2tm1.1Mfm)
decreased circulating tumor necrosis factor level J:179654
decreased tumor necrosis factor secretion J:179654
Rhbdf2tm1a(KOMP)Wtsi/Rhbdf2tm1a(KOMP)Wtsi
(involves: C57BL/6N)
decreased tumor necrosis factor secretion J:187583
Rhbdf2tm1Mak/Rhbdf2tm1Mak
(B6.129P2-Rhbdf2tm1Mak)
abnormal B cell physiology J:179653
abnormal immune serum protein physiology J:179653
decreased circulating tumor necrosis factor level J:179653
decreased susceptibility to infection induced morbidity/mortality J:179653
decreased tumor necrosis factor secretion J:179653
increased susceptibility to bacterial infection J:179653
increased susceptibility to bacterial infection induced morbidity/mortality J:179653
Rhbdf2tm1Mak/Rhbdf2tm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
abnormal leukocyte physiology J:221411
abnormal microglial cell physiology J:221411
decreased tumor necrosis factor secretion J:221411
Rhebtm1Pfw/Rhebtm1Pfw
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
immune system phenotype J:150108
Rhotm2.1Kpal/Rhotm2.1Kpal
(involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac)
microgliosis J:194158
Rhoatm1.1Tpal/Rhoa+
Tg(Cd4-cre/ERT2)11Gnri/0

(involves: C57BL/6)
increased regulatory T cell number J:257764
increased T cell proliferation J:257764
increased T follicular helper cell number J:257764
Rhobtb1em2(IMPC)Ccpcz/Rhobtb1em2(IMPC)Ccpcz
(C57BL/6N-Rhobtb1em2(IMPC)Ccpcz/Ccpcz)
increased Ly6C-positive NK T cell number J:211773
Rhobtb3tm1a(KOMP)Wtsi/Rhobtb3tm1a(KOMP)Wtsi
(involves: C57BL/6N)
decreased spleen weight J:226884
Rhoctm1Mak/Rhoctm1Mak
(involves: 129P2/OlaHsd)
immune system phenotype J:100482
Rhoftm1.2Dash/Rhoftm1.2Dash
(involves: 129)
abnormal spleen marginal zone morphology J:303076
decreased marginal zone B cell number J:303076
immune system phenotype J:303076
Rhogtm1Tnr/Rhogtm1Tnr
(involves: 129)
abnormal CD4-positive, alpha-beta T cell physiology J:87580
abnormal leukocyte physiology J:87580
abnormal T-helper 2 physiology J:87580
increased B cell proliferation J:87580
increased immunoglobulin level J:87580
Rhohtm1Brak/Rhohtm1Brak
(involves: 129/Sv * C57BL/6)
abnormal double-negative T cell morphology J:143161
abnormal immune system organ morphology J:143161
abnormal lymphocyte cell number J:143161
abnormal splenic cell ratio J:143161
abnormal T cell proliferation J:143161
decreased CD4-positive, alpha-beta T cell number J:143161
decreased CD8-positive, alpha-beta T cell number J:143161
decreased double-positive T cell number J:143161
decreased single-positive T cell number J:143161
decreased T cell apoptosis J:143161
decreased T cell number J:143161
decreased T cell proliferation J:143161
increased double-negative T cell number J:143161
increased gamma-delta T cell number J:143161
increased NK cell number J:143161
increased NK T cell number J:143161
increased T cell number J:143161
increased T cell proliferation J:143161
spleen hypoplasia J:143161
thymus hypoplasia J:143161
Rhohtm1Brak/Rhohtm1Brak
Itgb2tm2Bay/Itgb2tm2Bay

(involves: 129/Sv * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:143161
decreased CD8-positive, alpha-beta T cell number J:143161
decreased double-positive T cell number J:143161
decreased single-positive T cell number J:143161
increased double-negative T cell number J:143161
Rhohtm1Brak/Rhohtm1Brak
Tg(TcraTcrb)425Cbn/?

(involves: 129/Sv * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:143161
immune system phenotype J:143161
Rhohtm1Daw/Rhohtm1Daw
(involves: 129 * C57BL/6)
arrested T cell differentiation J:113565
decreased double-positive T cell number J:113565
decreased T cell number J:113565
thymus hypoplasia J:113565
Rhohtm1Hasu/Rhohtm1Hasu
(B6.Cg-Rhohtm1Hasu)
abnormal mast cell physiology J:143491
decreased mast cell degranulation J:143491
decreased susceptibility to type I hypersensitivity reaction J:143491
immune system phenotype J:143491
Rhs1C57BL/6/Rhs1C57BL/6
(involves: BALB/c * C57BL/6)
decreased susceptibility to Herpesvirales infection J:69352
Ric1tm1a(EUCOMM)Hmgu/Ric1tm1a(EUCOMM)Hmgu
(C57BL/6N-Ric1tm1a(EUCOMM)Hmgu/H)
decreased B cell number J:165965
decreased leukocyte cell number J:165965
decreased mature B cell number J:165965
Ric8btm1b(EUCOMM)Hmgu/Ric8b+
(C57BL/6N-Ric8btm1b(EUCOMM)Hmgu/Cnrm)
increased basophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Rictortm1.1Klg/Rictortm1.1Klg
Tg(Mx1-cre)1Cgn/0

(B6.Cg-Rictortm1.1Klg Tg(Mx1-cre)1Cgn)
abnormal double-negative T cell morphology J:189736
decreased DN1 thymic pro-T cell number J:189736
decreased DN2 thymocyte number J:189736
decreased DN3 thymocyte number J:189736
decreased DN4 thymocyte number J:189736
decreased double-positive T cell number J:189736
decreased single-positive T cell number J:189736
decreased T cell proliferation J:189736
decreased thymus weight J:189736
immune system phenotype J:189736
increased double-negative T cell number J:189736
thymus hypoplasia J:189736
Rictortm1.1Mnh/Rictortm1.1Mnh
Tg(Fabp4-cre)1Rev/0

(B6.Cg-Rictortm1.1Mnh Tg(Fabp4-cre)1Rev)
increased spleen weight J:150064
Rif1Gt(XT0278)Wtsi/Rif1Gt(XT0278)Wtsi
(involves: 129P2/OlaHsd * CD-1 * MF1)
abnormal class switch recombination J:195061
decreased IgA level J:195061
decreased IgG1 level J:195061
decreased IgG2b level J:195061
decreased IgG3 level J:195061
decreased IgG level J:195061
immune system phenotype J:195061
increased susceptibility to bacterial infection J:195061
Rigitm1Aki/Rigitm1Aki
(involves: 129/Sv * C57BL/6)
abnormal dendritic cell physiology J:137522
Rigitm1Aki/Rigitm1Aki
(involves: 129/Sv * C57BL/6 * ICR)
abnormal interferon level J:137522
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:137522
Rigitm1Zgwg/Rigitm1Zgwg
(involves: 129S1/Sv)
abnormal B cell differentiation J:139016
abnormal granulocyte morphology J:139016
abnormal granulocyte physiology J:139016
colitis J:139868
decreased Peyer's patch number J:139868
decreased T cell number J:139868
enlarged spleen J:139016
immune system phenotype J:139016
increased activated T cell number J:139868
increased granulocyte number J:139016
increased memory T cell number J:139868
increased susceptibility to induced colitis J:139868
small Peyer's patches J:139868
Rinltm1.1Boun/Rinltm1.1Boun
(B6.Cg-Rinltm1.1Boun)
abnormal susceptibility to Riboviria infection J:346452
enlarged spleen J:346452
immune system phenotype J:346452
increased B cell number J:346452
increased CD4-positive, alpha-beta T cell number J:346452
increased germinal center B cell number J:346452
increased splenocyte number J:346452
increased T follicular helper cell number J:346452
Rinltm1.1Boun/Rinltm1.1Boun
Tg(TcraTcrb)425Cbn/0

(involves: C57BL/6)
abnormal T follicular helper cell differentiation J:346452
increased CD4-positive, alpha-beta T cell number J:346452
increased T follicular helper cell number J:346452
Riok2tm1c(KOMP)Wtsi/Riok2+
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6N * C57BL/10 * CBA/Ca)
abnormal CD4-positive, alpha beta T cell morphology J:305794
abnormal CD4-positive, alpha-beta T cell physiology J:305794
abnormal circulating interleukin level J:305794
abnormal immune system morphology J:305794
abnormal interleukin secretion J:305794
decreased neutrophil cell number J:305794
increased monocyte cell number J:305794
increased NK T cell number J:305794
Riox1tm1Qch/Riox1tm1Qch
Tg(Prrx1-cre)1Cjt/0

(involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl * SJL/J)
decreased osteoclast cell number J:224562
Riox2tm1Mtsun/Riox2tm1Mtsun
(B6CrSlc.Cg-Riox2tm1Mtsun)
abnormal circulating interferon-gamma level J:201871
abnormal circulating interleukin-4 level J:201871
abnormal immunoglobulin level J:201871
decreased eosinophil cell number J:201871
decreased inflammatory response J:201871
decreased macrophage cell number J:201871
decreased neutrophil cell number J:201871
Ripk1tm1.1Vmd/Ripk1tm1.1Vmd
(involves: C57BL/6N)
increased thymocyte apoptosis J:209137
Ripk1tm1Led/Ripk1tm1Led
(involves: 129S6/SvEvTac)
abnormal immune system organ morphology J:46522
abnormal leukocyte cell number J:46522
abnormal lymph node morphology J:46522
abnormal thymus morphology J:46522
decreased thymocyte number J:46522
increased spleen red pulp amount J:46522
lymph node inflammation J:46522
lymph node necrosis J:46522
Ripk2tm1Cfl/Ripk2tm1Cfl
(involves: 129S5/SvEvBrd)
abnormal macrophage physiology J:107130
Ripk2tm1Flv/Ripk2tm1Flv
(involves: 129S1/Sv)
abnormal cytokine secretion J:75400
abnormal T-helper 1 physiology J:75400
decreased interleukin-6 secretion J:75400
decreased T cell proliferation J:75400
decreased tumor necrosis factor secretion J:75400
Ripk2tm1Flv/Ripk2tm1Flv
(involves: 129S1/Sv * C57BL/6)
abnormal macrophage physiology J:132126
decreased interleukin-6 secretion J:132126
decreased tumor necrosis factor secretion J:132126
Ripk2tm1Flv/Ripk2tm1Flv
Tnip1tm1.1Pcoh/Tnip1tm1.1Pcoh

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
enlarged lymph nodes J:176826
enlarged spleen J:176826
Ripk2tm1Ghc/Ripk2tm1Ghc
(involves: 129S4/SvJae * C57BL/6)
decreased IgG2a level J:75401
decreased interferon-gamma secretion J:75401
decreased T cell proliferation J:75401
increased susceptibility to infection J:75401
Ripk2tm2Cfl/Ripk2tm2Cfl
(involves: 129S5/SvEvBrd)
immune system phenotype J:107130
Ripk3tm1Vmd/Ripk3tm1Vmd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6N)
immune system phenotype J:87683
Ripk3tm1Vmd/Ripk3tm1Vmd
(B6.129-Ripk3tm1Vmd)
decreased inflammatory response J:179279
Ripk4tm1Pmh/Ripk4tm1Pmh
(involves: 129 * C57BL/6)
immune system phenotype J:78593
Ripply3tm1Sjt/Ripply3tm1Sjt
(involves: 129S1/Sv * C57BL/6)
abnormal thymus development J:167713
ectopic thymus J:167713
small thymus J:167713
Rit1tm1.1Tumg/Rit1+
(B6.Cg-Rit1tm1.1Tumg)
enlarged spleen J:277548
Rlimem1(IMPC)Rbrc/Rlim+
(C57BL/6NJcl-Rlimem1(IMPC)Rbrc/Rbrc)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Rmcfr/Rmcfr
(DBA/1J)
decreased susceptibility to Retroviridae infection J:7108
Rmcfr/Rmcfr
(DBA/2J)
decreased susceptibility to Retroviridae infection J:7108
Rmcfr/Rmcfr
(CBA/N)
decreased susceptibility to Retroviridae infection J:7108
Rmcfs/Rmcfs
(CBA/J)
increased susceptibility to Retroviridae infection J:7108
Rmcfs/Rmcfs
(C57L/J)
increased susceptibility to Retroviridae infection J:7108
Rmcfs/Rmcfs
(C57BR/cdJ)
increased susceptibility to Retroviridae infection J:7108
Rmp1DBA/2J/Rmp1DBA/2J
(involves: C57BL/6J * DBA/2J)
increased susceptibility to Poxviridae infection J:28150
Rmp2DBA/2J/Rmp2DBA/2J
(involves: C57BL/6J * DBA/2J)
increased susceptibility to Poxviridae infection J:11032
Rmp3DBA/2J/Rmp3DBA/2J
(involves: C57BL/6J * DBA/2J)
increased susceptibility to Poxviridae infection J:11032
Rmp4C57BL/6NCr/Rmp4C57BL/6NCr
(involves: C57BL/6NCr * DBA/2NCr)
decreased susceptibility to Poxviridae infection J:29241
Rmp5C57BL/6NCr/Rmp5C57BL/6NCr
(involves: C57BL/6NCr * DBA/2NCr)
decreased susceptibility to Poxviridae infection J:3240
Rmp6C57BL/6NCr/Rmp6C57BL/6NCr
(involves: C57BL/6NCr * DBA/2NCr)
decreased susceptibility to Poxviridae infection J:3240
Rnase6em1(IMPC)Tcp/Rnase6em1(IMPC)Tcp
(C57BL/6N-Rnase6em1(IMPC)Tcp/Tcp)
increased monocyte cell number J:211773
Rnase11em1(IMPC)Mbp/Rnase11em1(IMPC)Mbp
(C57BL/6N-Rnase11em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased lymphocyte cell number J:211773
small spleen J:211773
Rnase12em1(IMPC)Mbp/Rnase12em1(IMPC)Mbp
(C57BL/6N-Rnase12em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Rnase13em1(IMPC)Mbp/Rnase13em1(IMPC)Mbp
(C57BL/6N-Rnase13em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Rnaseh2aem1(IMPC)Tcp/Rnaseh2a+
(C57BL/6NCrl-Rnaseh2aem1(IMPC)Tcp/Tcp)
increased monocyte cell number J:211773
increased spleen weight J:211773
Rnaseh2atm1Crh/Rnaseh2atm1Crh
(Not Specified)
abnormal innate immunity J:232933
decreased susceptibility to Riboviria infection J:232933
Rnaseh2atm1Crh/Rnaseh2atm1Crh
Sting1tm1Gnb/Sting1tm1Gnb

(involves: 129P2/OlaHsd)
immune system phenotype J:232933
Rnaseh2bem1Anu/Rnaseh2b+
Tlr7em2Anu/Tlr7+

(C57BL/6NCrl-Rnaseh2bem1Anu Tlr7em2Anu)
abnormal immune system morphology J:324448
abnormal mature B cell morphology J:324448
increased autoantibody level J:324448
increased CD4-positive, alpha-beta T cell number J:324448
increased germinal center B cell number J:324448
increased plasma cell number J:324448
increased T follicular helper cell number J:324448
Rnaseh2btm1a(EUCOMM)Wtsi/Rnaseh2btm1a(EUCOMM)Wtsi
(involves: C57BL/6N)
thymus hypoplasia J:186986
Rnaseh2btm1c(EUCOMM)Wtsi/Rnaseh2btm1c(EUCOMM)Wtsi
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL)
decreased B cell proliferation J:186986
immune system phenotype J:186986
Rnaseltm1Slvm/Rnaseltm1Slvm
(involves: 129P2/OlaHsd)
abnormal thymus morphology J:44292
decreased T cell apoptosis J:44292
enlarged thymus J:44292
increased susceptibility to Picornaviridae infection J:44292
thymus hyperplasia J:44292
Rnaset2btm1b(EUCOMM)Hmgu/Rnaset2btm1b(EUCOMM)Hmgu
(C57BL/6N-Rnaset2btm1b(EUCOMM)Hmgu/H)
enlarged spleen J:211773
Rnd2em1(IMPC)Mbp/Rnd2em1(IMPC)Mbp
(C57BL/6NCrl-Rnd2em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Rnd3tm1b(EUCOMM)Hmgu/Rnd3+
(C57BL/6N-Rnd3tm1b(EUCOMM)Hmgu/H)
increased large unstained cell number J:211773
Rnf2tm1Mvi/Rnf2tm1Mvi
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10 * CBA)
abnormal B cell differentiation J:130397
decreased B cell number J:130397
decreased monocyte cell number J:130397
Rnf5tm1.1(KOMP)Vlcg/Rnf5+
(C57BL/6N-Rnf5tm1.1(KOMP)Vlcg/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Rnf5tm1.1(KOMP)Vlcg/Rnf5tm1.1(KOMP)Vlcg
(C57BL/6N-Rnf5tm1.1(KOMP)Vlcg/Ccpcz)
abnormal spleen morphology J:211773
Rnf8Gt(AS0574)Wtsi/Rnf8+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:161240
Rnf8Gt(AS0574)Wtsi/Rnf8Gt(AS0574)Wtsi
(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:161240
decreased B cell number J:161240
decreased CD4-positive, alpha-beta T cell number J:161240
decreased CD8-positive, alpha-beta T cell number J:161240
decreased double-negative T cell number J:161240
decreased double-positive T cell number J:161240
decreased IgG1 level J:161240
decreased IgG2b level J:161240
decreased IgG3 level J:161240
decreased immature B cell number J:161240
decreased pre-B cell number J:161240
decreased pro-B cell number J:161240
decreased splenocyte number J:161240
decreased T cell number J:161240
decreased thymocyte number J:161240
increased thymocyte apoptosis J:161240
Rnf8Gt(RRR260)Byg/Rnf8Gt(RRR260)Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal class switch recombination J:161240
decreased B cell number J:161240
decreased CD4-positive, alpha-beta T cell number J:161240
decreased CD8-positive, alpha-beta T cell number J:161240
decreased double-negative T cell number J:161240
decreased double-positive T cell number J:161240
decreased IgG1 level J:161240
decreased IgG2b level J:161240
decreased IgG3 level J:161240
decreased immature B cell number J:161240
decreased pre-B cell number J:161240
decreased pro-B cell number J:161240
decreased splenocyte number J:161240
decreased T cell number J:161240
decreased thymocyte number J:161240
increased thymocyte apoptosis J:161240
Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
(C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ics)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
(C57BL/6N-Rnf10tm1b(KOMP)Wtsi/H)
decreased spleen weight J:211773
increased large unstained cell number J:211773
Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
(C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Rnf19bem1(IMPC)Ccpcz/Rnf19b+
(C57BL/6N-Rnf19bem1(IMPC)Ccpcz/Ccpcz)
increased eosinophil cell number J:211773
Rnf19btm1Jkorn/Rnf19btm1Jkorn
(B6.129S-Rnf19btm1Jkorn)
decreased interferon-gamma secretion J:157393
impaired natural killer cell mediated cytotoxicity J:157393
Rnf20Gt(RRJ249)Byg/Rnf20+
(involves: 129P2/OlaHsd)
abnormal leukocyte physiology J:268221
abnormal T cell physiology J:268221
enlarged spleen J:268221
increased interferon-gamma secretion J:268221
increased spleen weight J:268221
increased susceptibility to induced colitis J:268221
increased tumor necrosis factor secretion J:268221
Rnf31tm1.1Kiwa/Rnf31tm1.1Kiwa
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6NCrlj * CBA/JNCrlj)
abnormal B-1 B cell morphology J:201885
abnormal humoral immune response J:201885
decreased B-1a cell number J:201885
decreased B-1b cell number J:201885
decreased IgA level J:201885
decreased IgG1 level J:201885
decreased IgG2a level J:201885
decreased IgG2b level J:201885
decreased IgG3 level J:201885
decreased IgM level J:201885
immune system phenotype J:201885
Rnf40tm1.1Sajo/Rnf40tm1.1Sajo
Tg(Car1-cre)5Flt/0

(involves: 129S2/SvPas * C57BL/6J)
decreased susceptibility to induced colitis J:311838
Rnf43em1(IMPC)Tcp/Rnf43em1(IMPC)Tcp
(C57BL/6NCrl-Rnf43em1(IMPC)Tcp/Tcp)
enlarged spleen J:211773
Rnf43em1Mage/Rnf43em1Mage
(Not Specified)
immune system phenotype J:276360
Rnf43em2Mage/Rnf43em2Mage
(Not Specified)
immune system phenotype J:276360
increased interferon-gamma secretion J:285428
stomach inflammation J:285428
Rnf115em1(IMPC)H/Rnf115em1(IMPC)H
(C57BL/6N-Rnf115em1(IMPC)H/H)
increased spleen weight J:211773
Rnf115em1Gpt/Rnf115em1Gpt
(C57BL/6JGpt-Rnf115em1Gpt/Gpt)
decreased susceptibility to viral infection J:297834
decreased susceptibility to viral infection induced morbidity/mortality J:297834
increased circulating interferon-beta level J:297834
increased interferon-beta secretion J:297834
increased susceptibility to viral infection induced morbidity/mortality J:297834
Rnf123em1Nmea/Rnf123em1Nmea
(NC/Jic-Rnf123em1Nmea)
decreased susceptibility to parasitic infection J:327312
decreased susceptibility to parasitic infection induced morbidity/mortality J:327312
Rnf123em2Nmea/Rnf123em2Nmea
(NC/Jic-Rnf123em2Nmea)
decreased susceptibility to parasitic infection J:327312
decreased susceptibility to parasitic infection induced morbidity/mortality J:327312
Rnf128tm1.1(KOMP)Vlcg/Y
(C57BL/6N-Rnf128tm1.1(KOMP)Vlcg/Ccpcz)
increased effector memory T-helper cell number J:211773
Rnf128tm1.1Flv/Y
(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:153216
abnormal peripheral T cell anergy J:153216
increased circulating interleukin-2 level J:153216
increased interferon-gamma secretion J:153216
increased T cell proliferation J:153216
Rnf128tm1.1Flv/Y
Tg(TcraTcrb)425Cbn/0

(involves: 129S6/SvEvTac * BALB/c * C57BL/6)
abnormal peripheral T cell anergy J:153216
decreased T cell proliferation J:153216
increased circulating interleukin-2 level J:153216
Rnf128tm1.1Flv/Rnf128tm1.1Flv
(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:153216
abnormal peripheral T cell anergy J:153216
increased circulating interleukin-2 level J:153216
increased interferon-gamma secretion J:153216
increased T cell proliferation J:153216
Rnf128tm1.1Flv/Rnf128tm1.1Flv
Tg(TcraTcrb)425Cbn/0

(involves: 129S6/SvEvTac * BALB/c * C57BL/6)
abnormal peripheral T cell anergy J:153216
decreased T cell proliferation J:153216
increased circulating interleukin-2 level J:153216
Rnf128tm1.2Cmse/Rnf128tm1.2Cmse
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal macrophage physiology J:245025
Rnf128tm1Cdon/Rnf128+
(involves: 129 * C57BL/6)
increased susceptibility to experimental autoimmune encephalomyelitis J:160681
Rnf128tm1Cdon/Rnf128tm1Cdon
(involves: C57BL/6)
increased anti-double stranded DNA antibody level J:160681
increased interferon-gamma secretion J:160681
increased interleukin-2 secretion J:160681
increased interleukin-17 secretion J:160681
increased T cell proliferation J:160681
Rnf128tm1Cdon/Rnf128tm1Cdon
(involves: 129 * C57BL/6)
abnormal immune tolerance J:160681
abnormal interleukin secretion J:160681
abnormal regulatory T cell physiology J:160681
CNS inflammation J:160681
decreased interleukin-4 secretion J:160681
decreased interleukin-5 secretion J:160681
decreased interleukin-13 secretion J:160681
enlarged mesenteric lymph nodes J:160681
enlarged spleen J:160681
increased anti-double stranded DNA antibody level J:160681
increased IgG1 level J:160681
increased IgM level J:160681
increased interferon-gamma secretion J:160681
increased interleukin-2 secretion J:160681
increased interleukin-4 secretion J:160681
increased interleukin-17 secretion J:160681
increased interleukin-21 secretion J:160681
increased splenocyte proliferation J:160681
increased susceptibility to experimental autoimmune encephalomyelitis J:160681
lung inflammation J:160681
Rnf128tm1Cdon/Rnf128tm1Cdon
Tg(TcraTcrb)425Cbn/0

(involves: 129 * BALB/c * C57BL/6)
abnormal immune tolerance J:160681
increased interferon-gamma secretion J:160681
increased interleukin-2 secretion J:160681
increased splenocyte proliferation J:160681
Rnf135em1(IMPC)Tcp/Rnf135em1(IMPC)Tcp
(C57BL/6NCrl-Rnf135em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Rnf139tm1(KOMP)Wtsi/Rnf139tm1(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
liver inflammation J:231404
Rnf144aem1Smoc/Rnf144aem1Smoc
(C57BL/6J-Rnf144aem1Smoc/Smoc)
abnormal innate immunity J:347002
increased susceptibility to Herpesvirales infection J:347002
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:347002
Rnf146tm1.1Rtpl/Rnf146tm1.1Rtpl
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6J)
abnormal osteoclast differentiation J:243612
increased circulating tumor necrosis factor level J:243612
increased osteoclast cell number J:243612
Rnf148em1(IMPC)Ccpcz/Rnf148em1(IMPC)Ccpcz
(C57BL/6N-Rnf148em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Rnf168em1(IMPC)H/Rnf168em1(IMPC)H
(C57BL/6NTac-Rnf168em1(IMPC)H/H)
decreased spleen weight J:211773
Rnf168Gt(156B6)Cmhd/Rnf168Gt(156B6)Cmhd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal class switch recombination J:198260
abnormal T cell receptor delta chain V(D)J recombination J:198260
decreased gamma-delta T cell number J:198260
decreased IgG1 level J:198260
decreased IgG2a level J:198260
decreased IgG3 level J:198260
decreased IgG level J:198260
immune system phenotype J:198260
increased DN3 thymocyte number J:198260
increased double-negative T cell number J:198260
Rnf168Gt(405F11)Cmhd/Rnf168Gt(405F11)Cmhd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal class switch recombination J:198260
abnormal T cell receptor delta chain V(D)J recombination J:198260
decreased gamma-delta T cell number J:198260
decreased IgG1 level J:198260
decreased IgG2a level J:198260
decreased IgG3 level J:198260
decreased IgG level J:198260
immune system phenotype J:198260
increased DN3 thymocyte number J:198260
increased double-negative T cell number J:198260
Rnf168tm2b(EUCOMM)Hmgu/Rnf168tm2b(EUCOMM)Hmgu
(C57BL/6N-Rnf168tm2b(EUCOMM)Hmgu/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased eosinophil cell number J:211773
Rnf169tm1a(EUCOMM)Hmgu/Rnf169tm1a(EUCOMM)Hmgu
(B6NTac;B6N-Rnf169tm1a(EUCOMM)Hmgu/H)
increased monocyte cell number J:165965
Rnf186em1Ktak/Rnf186em1Ktak
(involves: C57BL/6 * DBA/2)
increased susceptibility to colitis induced morbidity/mortality J:258197
increased susceptibility to induced colitis J:258197
Rnf186tm1Ktak/Rnf186tm1Ktak
(involves: 129S4/SvJae * C57BL/6)
increased susceptibility to colitis induced morbidity/mortality J:258197
increased susceptibility to induced colitis J:258197
Rnf208em1(IMPC)Ccpcz/Rnf208em1(IMPC)Ccpcz
(C57BL/6N-Rnf208em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
increased eosinophil cell number J:211773
Rnf216tm1b(EUCOMM)Wtsi/Rnf216tm1b(EUCOMM)Wtsi
(C57BL/6N-Rnf216tm1b(EUCOMM)Wtsi/Tcp)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Rnf223em1(IMPC)Ccpcz/Rnf223em1(IMPC)Ccpcz
(C57BL/6N-Rnf223em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Rnft2tm1b(EUCOMM)Hmgu/Rnft2tm1b(EUCOMM)Hmgu
(C57BL/6N-Rnft2tm1b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
Rnpepl1em1(IMPC)Mbp/Rnpepl1em1(IMPC)Mbp
(C57BL/6N-Rnpepl1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Ro60tm1Woln/Ro60+
(involves: 129S1/Sv * C57BL/6)
increased anti-nuclear antigen antibody level J:84627
increased IgG2a level J:84627
Ro60tm1Woln/Ro60tm1Woln
(involves: 129S1/Sv * C57BL/6)
glomerulonephritis J:84627
increased anti-chromatin antibody level J:84627
increased anti-double stranded DNA antibody level J:84627
increased anti-histone antibody level J:84627
increased anti-nuclear antigen antibody level J:84627
increased anti-single stranded DNA antibody level J:84627
increased IgG2a level J:84627
increased IgM level J:84627
Rock1tm1Liao/Rock1+
(C57BL/6-Rock1tm1Liao)
abnormal leukocyte adhesion J:135152
abnormal leukocyte migration J:135152
impaired macrophage chemotaxis J:135152
impaired neutrophil recruitment J:135152
Rock1tm1Sna/Rock1tm1Sna
(B6N.129X1-Rock1tm1Sna)
blepharitis J:98250
Rock2tm1.1Itl/Rock2+
Tg(Tagln-cre)1Her/0

(B6.Cg-Rock2tm1.1Itl Tg(Tagln-cre)1Her)
abnormal cytokine secretion J:222206
Ror1em1(IMPC)Ccpcz/Ror1+
(C57BL/6NCrl-Ror1em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Rorasg/Rorasg
(involves: C57BL/6)
abnormal immune system organ morphology J:2228
abnormal immune system physiology J:2228
abnormal macrophage physiology J:28095
immune system phenotype J:52105
increased IgE level J:135863
increased interleukin-1 secretion J:28095
lung inflammation J:135863
spleen atrophy J:2228
thymus atrophy J:2228
Rorcm1Btlr/Rorcm1Btlr
(C57BL/6J-Rorcm1Btlr)
decreased CD4-positive, alpha-beta T cell number J:203039
decreased CD8-positive, alpha-beta T cell number J:203039
Rorcm2Btlr/Rorcm2Btlr
(C57BL/6J-Rorcm2Btlr)
decreased IgM level J:217792
decreased response to antigen J:217792
impaired humoral immune response J:217792
Rorcm3Btlr/Rorcm3Btlr
(C57BL/6J-Rorcm3Btlr)
abnormal CD4-positive, alpha beta T cell morphology J:234257
decreased B-2 B cell number J:234257
decreased CD4-positive, alpha-beta T cell number J:234257
decreased CD8-positive, naive alpha-beta T cell number J:234257
decreased IgG level J:234257
decreased IgM level J:234257
decreased response to antigen J:234257
impaired humoral immune response J:234257
increased B-1a cell number J:234257
increased B-1b cell number J:234257
increased CD8-positive, alpha-beta T cell number J:234257
increased effector memory CD4-positive, alpha-beta T cell number J:234257
increased effector memory CD8-positive, alpha-beta T cell number J:234257
Rorctm1.1Zsun/Rorctm1.1Zsun
(B6(129S4)-Rorctm1.1Zsun)
abnormal T-helper 17 cell differentiation J:248565
absent Peyer's patches J:248565
decreased susceptibility to experimental autoimmune encephalomyelitis J:248565
small inguinal lymph nodes J:248565
Rorctm1Amj/Rorctm1Amj
(either: (involves: 129/Sv * C57BL/6) or (involves: 129/Sv * C57BL/6 * DBA/2))
abnormal interleukin level J:123351
abnormal lymph organ development J:64381
abnormal splenic cell ratio J:64381
abnormal T cell physiology J:64381
absent lymph nodes J:64381
absent Peyer's patches J:64381
decreased CD4-positive, alpha-beta T cell number J:64381
decreased CD8-positive, alpha-beta T cell number J:64381
decreased double-positive T cell number J:64381
decreased T cell number J:64381
decreased thymus weight J:64381
enlarged spleen J:64381
increased double-negative T cell number J:64381
increased T cell apoptosis J:64381
thymus hypoplasia J:64381
Rorctm1Litt/Rorctm1Litt
(involves: 129P2/OlaHsd)
abnormal CD8-positive, alpha-beta T cell differentiation J:248565
abnormal T cell differentiation J:128344, J:248565
abnormal T cell morphology J:248565
abnormal T-helper 17 cell differentiation J:248565
absent lymph nodes J:248565
colitis J:158663
decreased CD4-positive, alpha-beta T cell number J:248565
decreased double-positive T cell number J:248565
decreased susceptibility to experimental autoimmune encephalomyelitis J:248565
decreased thymocyte number J:248565
increased susceptibility to bacterial infection J:158663
increased susceptibility to bacterial infection induced morbidity/mortality J:158663
increased thymocyte apoptosis J:248565
Rorctm1Litt/Rorctm1Litt
Tcra-Jtm3.1Krg/Tcra-Jtm3.1Krg

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
abnormal T cell differentiation J:128344
Rorctm2Litt/Rorctm2Litt
(involves: 129P2/OlaHsd)
abnormal CD4-positive, alpha-beta intraepithelial T cell morphology J:91566
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology J:91566
abnormal gut-associated lymphoid tissue morphology J:87395, J:91566
abnormal lymph organ development J:87395
absent lymph nodes J:87395
absent Peyer's patches J:87395
decreased double-negative T cell number J:91566
decreased double-positive T cell number J:87395
decreased NK cell number J:142654
increased thymocyte apoptosis J:87395
Rosq1DBA/1J/Rosq1DBA/1J
(involves: DBA/1J * FVB/NJ)
abnormal neutrophil physiology J:122919
Rosq1DBA/1J/Rosq1FVB/NJ
(involves: DBA/1J * FVB/NJ)
abnormal neutrophil physiology J:122919
Rpa1tm1Wed/Rpa1+
(involves: 129/Sv * C57BL/6J * SJL)
increased lymphocyte cell number J:99303
Rpap3em1(IMPC)Mbp/Rpap3+
(C57BL/6N-Rpap3em1(IMPC)Mbp/Ucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Rpap3tm1c(KOMP)Wtsi/Rpap3tm1c(KOMP)Wtsi
Tg(Vil1-cre/ERT2)23Syr/0

(involves: C57BL/6N * DBA/2)
small intestinal inflammation J:314346
Rpe65tm1a(EUCOMM)Hmgu/Rpe65tm1a(EUCOMM)Hmgu
(C57BL/6N-Rpe65tm1a(EUCOMM)Hmgu/H)
decreased leukocyte cell number J:165965
increased leukocyte cell number J:165965
Rpeem1(IMPC)Mbp/Rpe+
(C57BL/6NCrl-Rpeem1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
(C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi)
absent connection between subcutaneous lymph vessels and lymph sac J:239583
absent spleen J:239583
spleen hypoplasia J:239583
Rpl12em1(IMPC)Mbp/Rpl12+
(C57BL/6NCrl-Rpl12em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Rpl13atm1.1Jesc/Rpl13atm1.1Jesc
(NOD.129S5(Cg)-Rpl13atm1.1Jesc)
decreased susceptibility to autoimmune diabetes J:237822
Rpl13atm1.1Mazu/Rpl13atm1.1Mazu
Lyz2tm1(cre)Ifo/Lyz2+

(involves: C57BL/6)
abnormal cytokine level J:194920
abnormal macrophage chemotaxis J:194920
increased circulating tumor necrosis factor level J:194920
Rpl22Gt(GST000137)Lex/Rpl22Gt(GST000137)Lex
(involves: 129S5/SvEvBrd)
abnormal T cell differentiation J:123569
abnormal T cell number J:123569
arrested T cell differentiation J:123569
decreased CD4-positive, alpha-beta T cell number J:123569
decreased CD8-positive, alpha-beta T cell number J:123569
decreased double-negative T cell number J:123569
decreased T cell number J:123569
glomerulonephritis J:123569
increased T cell apoptosis J:123569
thymus hypoplasia J:123569
Rpl22Gt(YHB332)Byg/Rpl22Gt(YHB332)Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal thymus development J:201164
decreased B cell number J:201164
decreased T cell number J:201164
Rpl27aSfa/Rpl27a+
(C57BL/6J-Rpl27aSfa)
decreased leukocyte cell number J:174216
small spleen J:174216
small thymus J:174216
Rpl38Ts/Rpl38+
(TSJ/Le)
increased susceptibility to otitis media J:168509
Rplp1tm1.1Melt/Rplp1tm1.2Melt
(Not Specified)
small thymus J:218949
Rprd1btm1Tshu/Rprd1btm1Tshu
Tg(Vil1-cre)20Syr/0

(involves: C57BL/6 * DBA/2)
increased susceptibility to colitis induced morbidity/mortality J:300857
Rps6ka3tm1.1Kry/Rps6ka3+
(involves: 129X1/SvJ)
immune system phenotype J:89403
Rps6ka3tm1.1Kry/Rps6ka3tm1.1Kry
(involves: 129X1/SvJ)
immune system phenotype J:89403
Rps6ka4tm1Jsca/Rps6ka4tm1Jsca
Rps6ka5tm1Jsca/Rps6ka5tm1Jsca

(Not Specified)
decreased T cell proliferation J:124301
spleen hypoplasia J:124301
Rps6ka4tm1Jsca/Rps6ka4tm1Jsca
Rps6ka5tm1Jsca/Rps6ka5tm1Jsca

(B6.Cg-Rps6ka5tm1Jsca Rps6ka4tm1Jsca)
abnormal cytokine level J:139576
abnormal cytokine secretion J:139576
decreased circulating interleukin-10 level J:139576
decreased interleukin-10 secretion J:139576
increased circulating interleukin-6 level J:139576
increased circulating interleukin-12a level J:139576
increased circulating interleukin-12b level J:139576
increased circulating tumor necrosis factor level J:139576
increased interleukin-6 secretion J:139576
increased interleukin-12a secretion J:139576
increased interleukin-12b secretion J:139576
increased susceptibility to endotoxin shock J:139576
increased tumor necrosis factor secretion J:139576
skin inflammation J:139576
Rps9tm1.1Geno/Rps9tm1.1Geno
(involves: C57BL/6)
decreased leukocyte cell number J:329922
increased monocyte cell number J:329922
Rps12em1.1Nbakr/Rps12+
(involves: C57BL/6J * FVB/N)
decreased leukocyte cell number J:338970
decreased spleen weight J:338970
Rps14tm1.1Ble/Rps14+
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6J * C57BL/6NTac * CBA/J)
enlarged spleen J:233322
Rps14tm1.1Ble/Rps14+
Tg(Mx1-cre)1Cgn/0
Trp53tm2.1Tyj/Trp53+

(involves: 129S4/SvJae * C57BL/6J * C57BL/6NTac * CBA/J)
immune system phenotype J:233322
Rps19bp1tm1.1(KOMP)Wtsi/Rps19bp1+
(C57BL/6N-Rps19bp1tm1.1(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm
(C57BL/6-Rps27lGt(IST11658B7)Tigm)
decreased spleen weight J:223276
decreased thymus weight J:223276
increased thymocyte apoptosis J:223276
thymus cortex hypoplasia J:223276
Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm
(involves: 129 * C57BL/6N)
spleen hypoplasia J:223276
thymus hypoplasia J:223276
Rps27lGt(IST11658B7)Tigm/Rps27lGt(IST11658B7)Tigm
Trp53tm1Tyj/Trp53+

(involves: 129S2/SvPas * C57BL/6N)
enlarged lymph nodes J:223276
enlarged spleen J:223276
Rptortm1Ahir/Rptortm1Ahir
Tg(Itgax-cre)1-1Reiz/0

(B6.Cg-Rptortm1Ahir Tg(Itgax-cre)1-1Reiz)
increased dendritic cell number J:188676
increased susceptibility to induced colitis J:188676
Rpusd2tm1b(KOMP)Wtsi/Rpusd2tm1b(KOMP)Wtsi
(C57BL/6N-Rpusd2tm1b(KOMP)Wtsi/Bay)
increased spleen weight J:211773
Rr7tm1.1Kio/Rr7tm1.1Kio
(involves: 129S4/SvJae * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:179326, J:164573
immune system phenotype J:164573
Rr7tm2.1Kio/Rr7tm2.1Kio
(involves: 129S4/SvJae * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:164573
immune system phenotype J:164573
Rr7tm3.1Kio/Rr7+
(B6.129S4-Rr7tm3.1Kio)
abnormal CD4-positive, alpha beta T cell morphology J:179326
Rr7tm3.1Kio/Rr7+
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S4/SvJae * C57BL/6 * C57BL/10 * CBA/Ca)
immune system phenotype J:179326
Rr7tm3.1Kio/Rr7+
Tg(CD2-icre)4Kio/0

(involves: 129S4/SvJae * C57BL/6 * C57BL/10 * CBA/Ca)
immune system phenotype J:179326
Rr7tm3.1Kio/Rr7+
Tg(Lck-cre)#Nik/0

(involves: 129S4/SvJae * C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:179326
Rr7tm4.1Kio/Rr7tm4.1Kio
(involves: 129S4/SvJae * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:179326
Rr7tm5.1Kio/Rr7tm5.1Kio
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:179326
Rr9tm1.1Kubo/Rr9tm1.1Kubo
(C57BL/6-Rr9tm1.1Kubo)
decreased interleukin-13 secretion J:167446
immune system phenotype J:167446
Rr10tm1.1Kubo/Rr10tm1.1Kubo
(B6.Cg-Rr10tm1.1Kubo)
immune system phenotype J:167446
Rr17tm1.1Cdon/Rr17tm1.1Cdon
(involves: 129S6/SvEvTac * C57BL/6)
decreased interleukin-17 secretion J:181186
decreased susceptibility to experimental autoimmune encephalomyelitis J:181186
immune system phenotype J:181186
increased interleukin-17 secretion J:181186
Rr32tm1.1Weav/Rr32tm1.1Weav
(involves: C57BL/6)
decreased interferon-gamma secretion J:208819
immune system phenotype J:208819
Rr38tm1.2Aafo/Rr38+
(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6)
decreased thymocyte number J:227747
immune system phenotype J:227747
Rr38tm1.2Aafo/Rr38tm1.2Aafo
(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6)
abnormal thymus physiology J:227747
decreased CD4-positive, alpha-beta T cell number J:227747
decreased CD8-positive, alpha-beta T cell number J:227747
decreased double-positive T cell number J:227747
decreased single-positive T cell number J:227747
decreased thymocyte number J:227747
decreased thymus weight J:227747
immune system phenotype J:227747
increased DN3 thymocyte number J:227747
small thymus J:227747
thymus hypoplasia J:227747
Rr39em1Ched/Rr39em1Ched
(C57BL/6-Rr39em1Ched)
decreased Ly6C low monocyte number J:239509
immune system phenotype J:239509
Rr79em2Rtew/Rr79em2Rtew
(C57BL/6J-Rr79em2Rtew/J)
abnormal T cell activation J:332957
abnormal T cell physiology J:332957
abnormal T cell subpopulation ratio J:332957
Rr79em2Rtew/Rr79em2Rtew
Tg(TcraTcrb)1100Mjb/?

(involves: C57BL/6J)
abnormal T cell activation J:332957
Rr94tm3.1Litt/Rr94+
Rr112tm4.1Litt/Rr112+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N)
immune system phenotype J:158962
Rr94tm3.1Litt/Rr94+
Tg(Cd4-cre)1Cwi/0
Rr112tm4.1Litt/Rr112+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N)
abnormal T cell differentiation J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
Rr94tm3.1Litt/Rr94tm3.1Litt
(involves: 129P2/OlaHsd * FVB/N)
immune system phenotype J:158962
Rr94tm3.1Litt/Rr94tm3.1Litt
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N)
abnormal T cell differentiation J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
decreased double-positive T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
Rr94tm3.2Litt/Rr94+
Rr112tm4.1Litt/Rr112+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N)
abnormal T cell differentiation J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
Rr94tm3.2Litt/Rr94tm3.2Litt
(involves: 129P2/OlaHsd * FVB/N)
abnormal CD4-positive, alpha beta T cell morphology J:158962
abnormal double-positive T cell morphology J:158962
abnormal T cell differentiation J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
decreased double-positive T cell number J:158962
immune system phenotype J:158962
increased CD8-positive, alpha-beta T cell number J:158962
Rr94tm3.2Litt/Rr94tm3.2Litt
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru

(involves: 129P2/OlaHsd * 129S2/SvPas * FVB/N)
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
immune system phenotype J:158962
increased CD8-positive, alpha-beta T cell number J:158962
Rr95em1Pdi/Rr95em1Pdi
(Not Specified)
immune system phenotype J:333574
Rr96tm1.1Tich/Rr96+
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sortm1(rtTA*M2)Jae

(involves: 129 * 129S4/SvJae * C57BL/6)
abnormal T cell differentiation J:191711
Rr96tm1.1Tich/Rr96+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+

(involves: 129 * 129S4/SvJae * C57BL/6)
abnormal CD4-positive T cell differentiation J:191711
Rr96tm1.1Tich/Rr96tm1.1Tich
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae

(involves: 129 * 129S4/SvJae * C57BL/6)
abnormal T cell differentiation J:191711
Rr96tm1.1Tich/Rr96tm1.1Tich
Tg(ACTB-tTS)1Mllo/?

(involves: 129 * C57BL/6)
decreased double-positive T cell number J:191711
Rr96tm1.1Yzo/Rr96tm1.1Yzo
(involves: 129P2/OlaHsd)
abnormal T cell differentiation J:130559
increased CD4-positive, alpha-beta T cell number J:130559
increased double-positive T cell number J:130559
Rr96tm1.1Yzo/Rr96tm1.1Yzo
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal T cell differentiation J:130559
Rr96tm1Yzo/Rr96tm1Yzo
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal T cell differentiation J:130559
increased double-positive T cell number J:130559
Rr96tm1Yzo/Rr96tm1Yzo
Tg(Cd8a-cre,-GFP)1Yzo/?

(involves: 129P2/OlaHsd)
increased double-positive T cell number J:130559
Rr96tm2Litt/Rr96+
Zbtb7btm1Itan/Zbtb7btm1Tani

(involves: 129 * 129P2/OlaHsd * C57BL/6)
abnormal double-negative T cell morphology J:141142
decreased CD8-positive, alpha-beta T cell number J:141142
Rr96tm2Litt/Rr96+
Zbtb7btm1Tani/Zbtb7btm1Tani

(involves: 129 * 129P2/OlaHsd * C57BL/6)
increased double-negative T cell number J:141142
Rr96tm2Litt/Rr96tm2Litt
(involves: 129P2/OlaHsd)
abnormal CD8-positive, alpha beta T cell morphology J:80690
Rr96tm2Litt/Rr96tm2Litt
Tfap4tm1.1Litt/Tfap4tm1.1Litt

(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal T cell differentiation J:176461
Rr97tm3Welm/Rr97tm3Welm
(involves: 129 * C57BL/6)
abnormal CD4-positive T cell differentiation J:126027
abnormal CD8-positive, alpha-beta T cell differentiation J:126027
abnormal dendritic cell morphology J:126027
abnormal double-positive T cell morphology J:126027
abnormal gamma-delta intraepithelial T cell morphology J:126027
abnormal T cell differentiation J:126027
Rr98tm1Welm/Rr98tm1Welm
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:113136
Rr99tm1Litt/Rr99tm1Litt
(either: (involves: 129P2/OlaHsd * AKR) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal CD8-positive, alpha beta T cell morphology J:50624
Rr100tm2.1Welm/Rr100+
(involves: 129P2/OlaHsd * AKR.1 * C57BL/6)
abnormal T cell differentiation J:113136
Rr100tm2.1Welm/Rr100tm2.1Welm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:113136
abnormal T cell subpopulation ratio J:113136
decreased CD8-positive, alpha-beta T cell number J:113136
decreased double-positive T cell number J:113136
increased CD4-positive, alpha-beta T cell number J:113136
Rr100tm2.1Welm/Rr100tm2.1Welm
(involves: 129P2/OlaHsd)
abnormal T cell differentiation J:158947
decreased CD8-positive, alpha-beta T cell number J:158947
decreased double-positive T cell number J:158947
immune system phenotype J:158947
increased CD4-positive, alpha-beta T cell number J:158947
Rr100tm2.1Welm/Rr100tm2.1Welm
Patz1tm1.1Welm/Patz1tm1.1Welm

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:158947
Rr100tm2.1Welm/Rr100tm2.1Welm
Tcratm1Mom/Tcratm1Mom

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
abnormal T cell morphology J:113136
Rr101tm2Kio/Rr101tm2Kio
(involves: 129S2/SvPas * C57BL/6 * DBA/2)
immune system phenotype J:110530
Rr104tm1.2Mym/Rr104tm1.2Mym
Tg(Epo*)458Mym/0

(involves: C57BL/6 * DBA/2)
abnormal spleen morphology J:231255
Rr123tm1.1Vbo/Rr123tm1.1Vbo
(involves: 129S4/SvJae * C57BL/6 * FVB/N)
abnormal regulatory T cell morphology J:191815
immune system phenotype J:191815
increased regulatory T cell number J:191815
Rr148tm1.1Fwa/Rr148tm1.1Fwa
(involves: 129S6/SvEvTac)
abnormal B cell differentiation J:101400
arrested B cell differentiation J:101400
decreased immature B cell number J:101400
immune system phenotype J:101400
small spleen J:101400
spleen hypoplasia J:101400
Rr148tm1.1Fwa/Rr148tm1.1Fwa
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv * 129S6/SvEvTac)
abnormal B cell differentiation J:101400
Rr148tm1Anbo/Rr148tm1Anbo
(involves: 129/Sv * C57BL/6 * FVB/N)
abnormal immunoglobulin heavy chain V(D)J recombination J:136307
decreased immature B cell number J:136307
decreased mature B cell number J:136307
decreased pre-B cell number J:136307
Rr148tm1Fwa/Rr148tm1Fwa
(129S6/SvEvTac-Rr148tm1Fwa)
abnormal immature B cell morphology J:101400
absent B cells J:101400
absent Peyer's patches J:101400
arrested B cell differentiation J:101400
immune system phenotype J:101400
small spleen J:101400
spleen hypoplasia J:101400
Rr148tm1Fwa/Rr148tm1Fwa
Rag2tm1Fwa/Rag2tm1Fwa

(involves: 129S/SvEv * 129S6/SvEvTac)
abnormal B cell differentiation J:101400
Rr148tm2Anbo/Rr148tm2Anbo
(involves: 129/Sv * C57BL/6 * FVB/N)
abnormal immunoglobulin heavy chain V(D)J recombination J:136307
decreased immature B cell number J:136307
decreased mature B cell number J:136307
decreased pre-B cell number J:136307
Rr155tm1.1Erpi/Rr155tm1.1Erpi
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal immunoglobulin level J:160101
decreased IgG1 level J:160101
decreased IgG2a level J:160101
immune system phenotype J:160101
Rr156tm6.1Cog/Rr156tm6.1Cog
(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:165617
decreased IgM level J:165617
immune system phenotype J:165617
Rr156tm6Cog/Rr156tm6Cog
(involves: 129P2/OlaHsd * C57BL/6)
decreased B cell number J:165617
decreased IgM level J:165617
immune system phenotype J:165617
Rr158tm1(Igh)Xu/Rr158tm1(Igh)Xu
(Not Specified)
abnormal immune system morphology J:124407
decreased B cell number J:124407
decreased immature B cell number J:124407
increased pre-B cell number J:124407
Rr158tm1Cgn/Rr158tm1Cgn
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S2/SvPas * C57BL/6))
abnormal B cell differentiation J:12574, J:64287
decreased mature B cell number J:64287
increased mature B cell number J:64287
spleen hypoplasia J:64287
Rr158tm2Cgn/Rr158tm2Cgn
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S2/SvPas * C57BL/6))
abnormal B cell differentiation J:12574
Rr158tm2Xu/Rr158tm2Xu
(Not Specified)
decreased B cell number J:124407
Rr159tm1.1Fwa/Rr159+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:113715
Rr159tm1.1Fwa/Rr159tm1.1Fwa
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:113715
decreased B cell number J:113715
Rr159tm1Fwa/Rr159+
(involves: 129P2/OlaHsd * C57BL/6)
increased B cell number J:113715
Rr159tm1Fwa/Rr159tm1Fwa
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:113715
decreased B cell number J:113715
Rr160tm1Wtg/Rr160tm1Wtg
(involves: 129S6/SvEvTac * C57BL/6)
abnormal immunoglobulin level J:134885
abnormal mature B cell morphology J:134885
abnormal somatic hypermutation frequency J:134885
decreased follicular B cell number J:134885
increased transitional stage B cell number J:134885
Rr161tm2.2Wtg/Rr161tm2.2Wtg
(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6)
abnormal B cell differentiation J:167472
abnormal immunoglobulin V(D)J recombination J:167472
decreased B cell number J:167472
decreased pro-B cell number J:167472
increased pre-B cell number J:167472
Rr162tm3.1Wtg/Rr162tm3.1Wtg
(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6)
abnormal immunoglobulin V(D)J recombination J:172855
immune system phenotype J:172855
Rr163tm1Lfdn/Rr163+
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CB20))
abnormal immune system physiology J:31727
immune system phenotype J:31727
Rr163tm1Lfdn/Rr163tm1Lfdn
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CB20))
abnormal immune system physiology J:31727
immune system phenotype J:31727
Rr166tm4.1Wtg/Rr166tm4.1Wtg
(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6)
abnormal B cell differentiation J:193015
abnormal B cell physiology J:193015
abnormal immunoglobulin level J:193015
abnormal immunoglobulin light chain V-J recombination J:193015
abnormal pre-B cell morphology J:193015
Rr169tm2Rao/Rr169+
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal T-helper 1 cell differentiation J:94039
Rr169tm2Rao/Rr169tm2Rao
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal T-helper 1 cell differentiation J:94039
increased susceptibility to parasitic infection J:94039
Rr170tm1.1Iku/Rr170tm1.1Iku
(B6.Cg-Rr170tm1.1Iku)
decreased T cell number J:333539
decreased T cell proliferation J:333539
immune system phenotype J:333539
increased T cell apoptosis J:333539
Rr185tm3Cog/Rr185tm3Cog
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell morphology J:71300
abnormal class switch recombination J:71300
decreased IgA level J:71300
decreased IgE level J:71300
decreased IgG1 level J:71300
decreased IgG2a level J:71300
decreased IgG2b level J:71300
decreased IgG3 level J:71300
decreased IgG level J:71300
decreased IgM level J:71300
decreased immunoglobulin level J:71300
immune system phenotype J:71300
Rr253em1Kmm/Rr253em1Kmm
(C57BL/6-Rr253em1Kmm)
abnormal class switch recombination J:316113
abnormal effector T cell number J:316113
abnormal peritoneal macrophage morphology J:316113
abnormal spleen B cell follicle morphology J:316113
decreased B cell number J:316113
decreased mature NK cell number J:316113
decreased monocyte cell number J:316113
decreased plasmacytoid dendritic cell number J:316113
decreased spleen B cell follicle number J:316113
decreased spleen B cell follicle size J:316113
increased dendritic cell number J:316113
increased lymphocyte cell number J:316113
increased neutrophil cell number J:316113
increased NK cell number J:316113
increased susceptibility to viral infection induced morbidity/mortality J:316113
increased T cell number J:316113
spleen hypoplasia J:316113
Rr253em3Kmm/Rr253em3Kmm
(C57BL/6J-Rr253em3Kmm)
decreased dendritic cell number J:334296
Rr253em4Kmm/Rr253em4Kmm
(C57BL/6J-Rr253em4Kmm)
immune system phenotype J:334296
Rr253em5Kmm/Rr253em5Kmm
(C57BL/6J-Rr253em5Kmm)
decreased dendritic cell number J:334296
increased dendritic cell number J:334296
Rr253em6Kmm/Rr253em6Kmm
(C57BL/6J-Rr253em6Kmm)
abnormal T-helper 2 physiology J:334296
decreased dendritic cell number J:334296
decreased monocyte cell number J:334296
decreased plasmacytoid dendritic cell number J:334296
immune system phenotype J:334296
increased dendritic cell number J:334296
increased susceptibility to parasitic infection induced morbidity/mortality J:334296
Rr270em1Mgn/Rr270em1Mgn
(involves: CD-1)
abnormal embryonic lymph sac morphology J:328045
Rr308tm1.1Fwa/Rr308tm1.1Fwa
(involves: 129P2/OlaHsd)
abnormal T cell differentiation J:82616, J:82395
abnormal T cell receptor alpha chain V-J recombination J:82616
Rr308tm1Fwa/Rr308tm1Fwa
(involves: 129P2/OlaHsd)
abnormal T cell differentiation J:82616
abnormal T cell receptor alpha chain V-J recombination J:82616
Rr308tm2Fwa/Rr308tm2Fwa
(Not Specified)
abnormal T cell differentiation J:82395
Rr338em1Jeng/Rr338em1Jeng
(Not Specified)
abnormal T cell differentiation J:232438
abnormal T cell number J:232438
decreased CD4-positive, alpha-beta T cell number J:232438
Rr347em1Prdns/Rr347em1Prdns
(CBA/Ca-Rr347em1Prdns)
absent Langerhans cell J:281171
decreased macrophage cell number J:281171
decreased microglial cell number J:281171
immune system phenotype J:281171
increased Ly6C low monocyte number J:281171
Rr364tm1.1Aak/Rr364tm1.1Aak
(129.129S2(Cg)-Rr364tm1.1Aak)
abnormal class switch recombination J:242276
decreased IgG3 level J:242276
increased IgG2a level J:242276
increased IgG2b level J:242276
Rr381em1Kap/Rr381em1Kap
(involves: C57BL/6)
absent CD8-positive, alpha-beta T cells J:333471
Rr381em4Kap/Rr381em4Kap
(involves: C57BL/6)
absent CD8-positive, alpha-beta T cells J:333471
Rr381em5Kap/Rr381em5Kap
(involves: C57BL/6)
absent CD8-positive, alpha-beta T cells J:333471
Rr383tm1Caob/Rr383tm1Caob
(B6.Cg-Rr383tm1Caob)
decreased osteoclast cell number J:131132
Rr386em1Pdi/Rr386em1Pdi
(involves: C57BL/6J)
immune system phenotype J:333574
Rr394em1Bhao/Rr394em1Bhao
(Not Specified)
abnormal T cell receptor alpha chain V-J recombination J:333961
decreased thymocyte number J:333961
increased DN3 thymocyte number J:333961
Rr395em1Bhao/Rr395em1Bhao
(Not Specified)
decreased double-positive T cell number J:333961
decreased thymocyte number J:333961
increased DN4 thymocyte number J:333961
increased thymocyte apoptosis J:333961
Rr149356tm1.1Pf/Rr149356tm1.1Pf
(either: 129P2/OlaHsd-Rr149356tm1.1Pf or (involves: 129P2/OlaHsd * BALB/c))
abnormal T cell differentiation J:34311
abnormal thymus cortex morphology J:34311
abnormal thymus medulla morphology J:34311
abnormal thymus morphology J:34311
arrested T cell differentiation J:34311
decreased double-positive T cell number J:34311
decreased single-positive T cell number J:34311
decreased T cell number J:34311
decreased thymocyte number J:34311
increased double-negative T cell number J:34311
increased gamma-delta T cell number J:34311
lymph node hypoplasia J:34311
Rr149356tm1Abnd/Rr149356tm1Abnd
(involves: 129S1/Sv * 129X1/SvJ)
abnormal T cell differentiation J:137580
abnormal thymus morphology J:137580
arrested T cell differentiation J:137580
decreased double-positive T cell number J:137580
decreased single-positive T cell number J:137580
decreased T cell number J:137580
increased double-negative T cell number J:137580
increased gamma-delta T cell number J:137580
thymus hypoplasia J:137580
Rr149356tm1Che/Rr149356tm1Che
(involves: 129S4/SvJae * C57BL/6)
abnormal double-negative T cell morphology J:106246, J:107306
abnormal double-positive T cell morphology J:106246, J:107306
Rr149356tm1Che/Rr149356tm1Che
Tcrdtm1Mom/Tcrdtm1Mom
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6)
abnormal double-negative T cell morphology J:106246
Rr149356tm1Che/Rr149356tm1Che
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6)
abnormal double-negative T cell morphology J:106246
abnormal double-positive T cell morphology J:106246
Rr250409tm1Lky/Rr250409+
(involves: 129X1/SvJ * BALB/c * C57BL/6 * FVB)
decreased interleukin-4 secretion J:125684
Rr250409tm1Lky/Rr250409tm1Lky
(involves: 129X1/SvJ * BALB/c * C57BL/6 * FVB)
abnormal response to infection J:125684
decreased IgE level J:125684
decreased interleukin-4 secretion J:125684
decreased interleukin-5 secretion J:125684
decreased interleukin-13 secretion J:125684
decreased susceptibility to parasitic infection J:125684
Rr250409tm1Lky/Rr250409tm1Lky
(involves: 129X1/SvJ * BALB/c)
decreased interleukin-4 secretion J:167446
Rr275254tm2.1Dhr/Rr275254tm2.1Dhr
(involves: 129S4/SvJae * C57BL/6)
abnormal gamma-delta T cell differentiation J:75624
abnormal T cell receptor gamma chain V-J recombination J:75624
Rr275254tm2Dhr/Rr275254tm2Dhr
(involves: 129S4/SvJae)
abnormal gamma-delta T cell differentiation J:75624
abnormal T cell receptor gamma chain V-J recombination J:75624
Rr282726tm1Dhr/Rr282726tm1Dhr
(involves: 129S4/SvJae * C57BL/6)
abnormal gamma-delta T cell differentiation J:75624
abnormal T cell receptor gamma chain V-J recombination J:75624
Rr282729tm1.1Iku/Rr282729tm1.1Iku
(C57BL/6J-Rr316tm1.1Iku)
abnormal T cell receptor gamma chain V-J recombination J:288442
decreased gamma-delta T cell number J:288442
Rr299391tm1.1Fwa/Rr299391+
(involves: 129P2/OlaHsd * FVB/N)
decreased T cell number J:55401
decreased thymocyte number J:55401
Rr299391tm1.1Fwa/Rr299391tm1.1Fwa
(involves: 129P2/OlaHsd * FVB/N)
decreased T cell number J:55401
decreased thymocyte number J:55401
Rragcem1Efe/Rragc+
(Not Specified)
abnormal B cell activation J:320567
abnormal B cell physiology J:320567
abnormal class switch recombination J:320567
decreased B cell proliferation J:320567
decreased germinal center B cell number J:320567
decreased IgG1 level J:320567
decreased IgM level J:320567
decreased plasma cell number J:320567
decreased spleen germinal center size J:320567
impaired humoral immune response J:320567
Rragcem1Efe/Rragc+
Tg(Vav-BCL2)69Jad/0

(Not Specified)
decreased germinal center B cell number J:320567
decreased spleen germinal center size J:320567
decreased susceptibility to autoimmune disorder J:320567
Rras2em1(IMPC)Ccpcz/Rras2em1(IMPC)Ccpcz
(C57BL/6NCrl-Rras2em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased NK cell number J:211773
Rras2Gt(OST361011)Lex/Rras2+
(involves: 129S5/SvEvBrd)
decreased B cell number J:151653
decreased follicular B cell number J:151653
decreased marginal zone B cell number J:151653
decreased memory T cell number J:151653
decreased spleen B cell follicle size J:151653
decreased spleen weight J:151653
decreased T cell number J:151653
spleen hypoplasia J:151653
Rras2Gt(OST361011)Lex/Rras2Gt(OST361011)Lex
(involves: 129S5/SvEvBrd)
abnormal B cell activation J:151653
abnormal B cell physiology J:151653
abnormal CD4-positive, alpha-beta T cell physiology J:151653
abnormal CD8-positive, alpha-beta T cell physiology J:151653
abnormal lymph node germinal center morphology J:151653
decreased B cell number J:151653
decreased B cell proliferation J:151653
decreased follicular B cell number J:151653
decreased marginal zone B cell number J:151653
decreased memory T cell number J:151653
decreased spleen B cell follicle size J:151653
decreased spleen weight J:151653
decreased T cell number J:151653
spleen hypoplasia J:151653
Rras2Gt(OST361011)Lex/Rras2Gt(OST361011)Lex
(B6.129S5-Rras2Gt(OST361011)Lex)
decreased B cell number J:151653
decreased memory T cell number J:151653
decreased T cell number J:151653
RrasGt(OST24882)Lex/RrasGt(OST24882)Lex
(B6;129S5-RrasGt(OST24882)Lex/Ieg)
decreased B cell number J:82809
increased CD4-positive, alpha-beta T cell number J:82809
increased CD8-positive, alpha-beta T cell number J:82809
Rrastm1Itl/Rrastm1Itl
(either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6))
immune system phenotype J:181730
Rrastm1Itl/Rrastm1Itl
(involves: 129S6/SvEvTac * C57BL/6)
abnormal dendritic cell morphology J:181730
abnormal dendritic cell physiology J:181730
Rreb1tm1b(EUCOMM)Wtsi/Rreb1+
(C57BL/6N-Rreb1tm1b(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Rrm2bGt(OST85254)Lex/Rrm2bGt(OST85254)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
spleen atrophy J:186071
thymus atrophy J:186071
Rrm2btm1Ynak/Rrm2btm1Ynak
(involves: 129 * C57BL/6J)
abnormal mesenteric lymph node morphology J:84841
decreased spleen white pulp amount J:84841
thymus cortex hypoplasia J:84841
Rsad1tm1.1(KOMP)Vlcg/Rsad1+
(C57BL/6N-Rsad1tm1.1(KOMP)Vlcg/Ucd)
enlarged lymph nodes J:211773
small thymus J:211773
Rsad1tm1.1(KOMP)Vlcg/Rsad1tm1.1(KOMP)Vlcg
(C57BL/6N-Rsad1tm1.1(KOMP)Vlcg/Ucd)
enlarged lymph nodes J:211773
Rsad2tm1Aki/Rsad2tm1Aki
(involves: 129/Sv * C57BL/6)
decreased circulating interferon-alpha level J:169840
decreased interferon-alpha secretion J:169840
decreased interferon-beta secretion J:169840
Rsad2tm1Kchc/Rsad2tm1Kchc
(B6.129-Rsad2tm1Kchc)
abnormal T-helper 2 cell differentiation J:148305
decreased IgG1 level J:148305
decreased interleukin-4 secretion J:148305
decreased interleukin-5 secretion J:148305
decreased interleukin-13 secretion J:148305
increased interferon-gamma secretion J:148305
rsm1/rsm1
(either: P/J or P/N)
abnormal cell-mediated immunity J:8396
Rsph9em1Jwji/Rsph9em1Jwji
(B6.Cg-Rsph9em1Jwji)
increased microglial cell activation J:294184
microgliosis J:294184
sinus inflammation J:294184
Rspo1tm2b(KOMP)Wtsi/Rspo1tm2b(KOMP)Wtsi
(C57BL/6N-Rspo1tm2b(KOMP)Wtsi/Ics)
increased lymphocyte cell number J:211773
Rtcbtm1c(KOMP)Wtsi/Rtcbtm1c(KOMP)Wtsi
Tg(Fcer2a-cre)5Mbu/0

(involves: C57BL/6 * CBA * SJL)
abnormal B cell number J:216740
abnormal B cell physiology J:216740
abnormal plasma cell morphology J:216740
decreased IgM level J:216740
Rthyd1NOD/MrkTac/?
(involves: B10.Br/SgSnJ * NOD-H2k)
abnormal T cell clonal deletion J:94684
Rthyd2B10.Br/SgSnJ/?
(involves: B10.Br/SgSnJ * NOD-H2k)
abnormal T cell clonal deletion J:94684
Rthyd3B10.Br/SgSnJ/?
(involves: B10.Br/SgSnJ * NOD-H2k)
abnormal T cell clonal deletion J:94684
Rthyd5NOD/MrkTac/?
(involves: B10.Br/SgSnJ * NOD-H2k)
abnormal T cell clonal deletion J:94684
Rtl5em1Tmki/Rtl5em1Tmki
Rtl6tm2.1Tmki/Rtl6tm2.1Tmki

(involves: C57BL/6NCrlj * C57BL/6NSlc * CBA/JNCrlj)
abnormal inflammatory response J:329352
decreased susceptibility to endotoxin shock J:329352
Rtl5tm1.1Tmki/Rtl5tm1.1Tmki
(involves: C57BL/6NCrlj * CBA/JNCrlj)
immune system phenotype J:329352
Rtl5tm1.1Tmki/Rtl5tm1.1Tmki
Rtl6tm1.1Tmki/Rtl6tm1.1Tmki

(involves: C57BL/6NCrlj * C57BL/6NSlc * CBA/JNCrlj)
abnormal inflammatory response J:329352
Rtl9em2Tmki/Rtl9em2Tmki
(C57BL/6N-Rtl9em2Tmki)
abnormal innate immunity J:343808
Rtn4rl2em1(IMPC)Mbp/Rtn4rl2em1(IMPC)Mbp
(C57BL/6NCrl-Rtn4rl2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Rtp4em#Xzs/Rtp4em#Xzs
(involves: C57BL/6)
decreased susceptibility to parasitic infection J:293929
decreased susceptibility to parasitic infection induced morbidity/mortality J:293929
decreased susceptibility to viral infection J:293929
Rtraftm1b(EUCOMM)Hmgu/Rtraf+
(C57BL/6N-Rtraftm1b(EUCOMM)Hmgu/H)
increased eosinophil cell number J:211773
Rttnem1(IMPC)Tcp/Rttn+
(C57BL/6NCrl-Rttnem1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Rubcnem1Dgre/Rubcnem1Dgre
(C57BL/6-Rubcnem1Dgre)
abnormal macrophage physiology J:261225
immune system phenotype J:261225
Rubcnem1Dgre/Rubcnem1Dgre
(involves: C57BL/6 * C57BL/6N)
abnormal circulating chemokine level J:235399
abnormal macrophage physiology J:235399
abnormal spleen morphology J:235399
decreased circulating interleukin-10 level J:235399
glomerulonephritis J:235399
increased anti-double stranded DNA antibody level J:235399
increased anti-nuclear antigen antibody level J:235399
increased autoantibody level J:235399
increased CD8-positive, alpha-beta T cell number J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
increased circulating interleukin-12b level J:235399
increased IgG level J:235399
increased lymphocyte cell number J:235399
increased monocyte cell number J:235399
increased neutrophil cell number J:235399
increased susceptibility to systemic lupus erythematosus J:235399
Rubcnem1Dgre/Rubcnem1Dgre
Tg(CAG-EGFP/Map1lc3b)53Nmz/0

(involves: C57BL/6 * C57BL/6J * C57BL/6N * C57BL/6NCrlj * DBA/2)
abnormal macrophage morphology J:261225
abnormal macrophage physiology J:261225
Rubcnem1Dgre/Rubcnem1Dgre
Tg(CAG-EGFP/Map1lc3b)53Nmz/0

(involves: C57BL/6 * C57BL/6N * DBA/2)
abnormal circulating chemokine level J:235399
abnormal macrophage physiology J:235399
decreased circulating interleukin-10 level J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
Rufy4em1(IMPC)Mbp/Rufy4em1(IMPC)Mbp
(C57BL/6N-Rufy4em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Runx1tm1(RUNX1)Gcg/Runx1tm1(RUNX1)Gcg
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * C57BL/6 * CBA)
abnormal granulocyte differentiation J:106800
abnormal myelopoiesis J:106801
abnormal T cell differentiation J:106800
decreased CD4-positive, alpha-beta T cell number J:106800
decreased double-positive T cell number J:106800
increased CD8-positive, alpha-beta T cell number J:106800
Runx1tm1(RUNX1/EVI1)Kmit/Runx1+
(involves: C57BL/6 * CBA)
abnormal myelopoiesis J:118892
Runx1tm1Itan/Runx1tm1Itan
(involves: 129P2/OlaHsd)
immune system phenotype J:132661
Runx1tm1Soga/Runx1tm1.1Soga
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal B cell differentiation J:88511
abnormal T cell differentiation J:88511
Runx1tm1Soga/Runx1tm1Soga
Stag2tm1.1Soga/Y
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6J * C57BL/6N * CBA/J)
decreased leukocyte cell number J:289000
Runx1tm1Spe/Runx1+
(either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6))
decreased CD4-positive, alpha-beta T cell number J:120100
Runx1tm1Spe/Runx1tm1Spe
(either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6))
impaired myelopoiesis J:35115
Runx1tm1Tani/Runx1tm1Tani
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:125959
Runx1tm1Tani/Runx1tm1Tani
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal CD4-positive T cell differentiation J:125959
abnormal CD8-positive, alpha-beta T cell differentiation J:125959
abnormal double-positive T cell morphology J:125959
decreased CD4-positive, alpha-beta T cell number J:125959
Runx1tm1Tani/Runx1tm1Tani
Tg(Lck-cre)1Cwi/?

(involves: 129P2/OlaHsd)
arrested T cell differentiation J:125959
decreased double-positive T cell number J:125959
decreased thymocyte number J:125959
increased double-negative T cell number J:125959
Runx1tm1Toku/Runx1+
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:131081
Runx1tm1Toku/Runx1tm1Toku
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell subpopulation ratio J:87697
increased CD4-positive, alpha-beta T cell number J:87697
small thymus J:87697
thymus hypoplasia J:87697
Runx1tm1Toku/Runx1tm1Toku
Runx3tm1Itan/Runx3+
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:131081
decreased CD8-positive, alpha-beta T cell number J:131081
Runx1tm1Toku/Runx1tm1Toku
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:131081
decreased CD8-positive, alpha-beta T cell number J:131081
Runx1tm1Toku/Runx1tm1Toku
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:131081
Runx1tm1Yg/Runx1tm1Yg
(either: (involves: 129/Sv * 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1))
abnormal leukopoiesis J:125830
abnormal T cell differentiation J:125830
abnormal thymus corticomedullary boundary morphology J:125830
abnormal thymus lobule morphology J:125830
decreased single-positive T cell number J:125830
decreased thymocyte number J:125830
increased double-positive T cell number J:125830
increased thymocyte apoptosis J:125830
small thymus J:125830
thymus cyst J:125830
thymus hypoplasia J:125830
Runx1tm1Yg/Runx1tm1Yg
Tg(Lck-cre)1Jtak/?

(either: (involves: 129/Sv * 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1))
decreased T cell number J:125830
Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell subpopulation ratio J:87697
Runx1tm2.1Gss/Runx1tm2.1Gss
(involves: 129S4/SvJae * C57BL/6)
abnormal leukocyte morphology J:214025
abnormal spleen white pulp morphology J:214025
decreased CD8-positive, alpha-beta T cell number J:214025
decreased immature B cell number J:214025
decreased pre-pro B cell number J:214025
enlarged spleen J:214025
increased granulocyte number J:214025
increased macrophage cell number J:214025
increased mature B cell number J:214025
increased monocyte cell number J:214025
increased pro-B cell number J:214025
myeloid hyperplasia J:214025
Runx1tm2Buch/Runx1tm2Buch
Tg(Mx1-cre)1Cgn/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal immune system organ morphology J:105709
abnormal leukocyte morphology J:105709
abnormal lymph node size J:105709
abnormal thymus lobule morphology J:105709
decreased CD4-positive, alpha-beta T cell number J:105709
decreased CD8-positive, alpha-beta T cell number J:105709
decreased double-positive T cell number J:105709
decreased lymphocyte cell number J:105709
decreased mature B cell number J:105709
decreased spleen white pulp amount J:105709
decreased T cell number J:105709
decreased thymus weight J:105709
impaired myelopoiesis J:105709
increased mast cell number J:105709
increased monocyte cell number J:105709
increased neutrophil cell number J:105709
increased spleen red pulp amount J:105709
increased spleen weight J:105709
small Peyer's patches J:105709
Runx1tm2Itan/Runx1tm2Itan
(involves: 129P2/OlaHsd)
immune system phenotype J:132661
Runx1tm3(Runx3)Toku/Runx1tm3(Runx3)Toku
(involves: 129P2/OlaHsd)
abnormal thymus medulla morphology J:98965
decreased leukocyte cell number J:98965
decreased lymphocyte cell number J:98965
decreased thymocyte number J:98965
small spleen J:98965
small thymus J:98965
thymus hypoplasia J:98965
Runx1tm3Itan/Runx1tm3Itan
(involves: 129P2/OlaHsd * C57BL/6)
decreased leukocyte cell number J:160791
Runx1tm3Itan/Runx1tm3Itan
(involves: 129P2/OlaHsd)
abnormal axillary lymph node morphology J:168918
abnormal inguinal lymph node morphology J:168918
abnormal lymph organ development J:168918
abnormal Peyer's patch morphology J:168918
decreased CD4-positive, alpha-beta T cell number J:168918
decreased Peyer's patch number J:168918
decreased thymocyte number J:168918
small Peyer's patches J:168918
Runx1tm3Spe/Runx1tm3Spe
Spi1tm2.1Dgt/Spi1tm2.1Dgt
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
decreased B cell number J:131217
decreased thymus weight J:131217
increased granulocyte number J:131217
increased spleen weight J:131217
Runx1tm3Spe/Runx1tm3Spe
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
arrested T cell differentiation J:131217
decreased B cell number J:151639
decreased double-negative T cell number J:131217
decreased thymus weight J:131217
increased double-negative T cell number J:131217
increased spleen weight J:131217
Runx1tm3Spe/Runx1tm3Spe
Tg(VAV1-cre)1Graf/0

(involves: 129S4/SvJae)
decreased B cell number J:145700
decreased double-positive T cell number J:145700
decreased lymphocyte cell number J:145700
decreased thymocyte number J:145700
increased granulocyte number J:145700
increased monocyte cell number J:145700
Runx1tm4(Runx2)Toku/Runx1tm4(Runx2)Toku
(involves: 129P2/OlaHsd)
decreased leukocyte cell number J:98965
Runx1tm4Spe/Runx1+
(involves: 129/Sv * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:120100
Runx1tm4Spe/Runx1tm4Spe
(involves: 129/Sv * C57BL/6)
decreased leukocyte cell number J:120100
decreased lymphocyte cell number J:120100
increased monocyte cell number J:120100
Runx1tm5Spe/Runx1+
(involves: 129/Sv * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:120100
Runx1tm6Spe/Runx1+
(involves: 129/Sv * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:120100
Runx1tm7Spe/Runx1+
(involves: 129/Sv * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:120100
Runx1tm8Spe/Runx1+
(involves: 129/Sv * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:120100
Runx1tm8Spe/Runx1tm8Spe
(involves: 129/Sv * C57BL/6)
lung inflammation J:120100
Runx2tm1Kish/Runx2+
(involves: 129P2/OlaHsd * C57BL/6)
enlarged thymus J:162258
Runx2tm1Kish/Runx2tm1Kish
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:59821, J:40783
abnormal splenic cell ratio J:53069
decreased B cell number J:53069
decreased thymocyte number J:40783
enlarged spleen J:53069
increased granulocyte number J:53069
Runx3tm1Itan/Runx3tm1Itan
Tg(Cd4-cre)1Cwi/0

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
abnormal CD8-positive, alpha beta T cell morphology J:125953
abnormal CD8-positive, alpha-beta T cell differentiation J:125953
decreased CD8-positive, alpha-beta T cell number J:131081
increased IgA level J:125953
lung inflammation J:125953
Runx3tm1Litt/Runx3tm1Litt
(involves: 129P2/OlaHsd)
abnormal CD8-positive, alpha-beta T cell differentiation J:141144
abnormal double-positive T cell morphology J:141144
Runx3tm1Yg/Runx3tm1Yg
(either: (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1))
abnormal cytokine level J:93240
abnormal dendritic cell differentiation J:88424
abnormal dendritic cell morphology J:88424
abnormal dendritic cell physiology J:88424, J:100348
abnormal inflammatory response J:93240
abnormal interferon level J:93240
abnormal interleukin level J:93240
abnormal mesenteric lymph node morphology J:93240
abnormal tumor necrosis factor level J:93240
absent Langerhans cell J:88424
colitis J:93240
increased dendritic cell number J:88424, J:100348
increased IgE level J:100348
intestinal inflammation J:93240
lung inflammation J:88424
small intestinal inflammation J:93240
stomach inflammation J:93240
Runx3tm1Yg/Runx3tm1Yg
(involves: 129S1/Sv * 129X1/SvJ)
abnormal CD8-positive, alpha beta T cell morphology J:109584
Runx3tm2Yg/Runx3tm2Yg
(involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * ICR)
abnormal CD8-positive, alpha beta T cell morphology J:109584
abnormal dendritic cell differentiation J:109584
Runx3tm3.1Yg/Runx3tm3.1Yg
(Not Specified)
abnormal immune system physiology J:224898
absent Langerhans cell J:224898
intestinal inflammation J:224898
Ruvbl1tm1.1Oxbk/Ruvbl1tm1.1Oxbk
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA/J * SJL)
bone marrow failure J:220926
Ruvbl2M1Btlr/Ruvbl2+
(involves: C57BL/6J)
abnormal class switch recombination J:185495
decreased CD4-positive, alpha-beta T cell number J:185495
decreased CD8-positive, alpha-beta T cell number J:185495
decreased double-positive T cell number J:185495
decreased IgG1 level J:185495
decreased IgG level J:185495
decreased IgM level J:185495
decreased T cell number J:185495
immune system phenotype J:185495
increased thymocyte number J:185495
Rwdd1tm1b(KOMP)Wtsi/Rwdd1tm1b(KOMP)Wtsi
(C57BL/6N-Rwdd1tm1b(KOMP)Wtsi/Wtsi)
decreased CD8-positive, alpha-beta T cell number J:211773
decreased Ly6C-positive mature NK cell number J:211773
decreased regulatory T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased memory-marker gamma-delta T cell number J:211773
Rwdd2aem1(IMPC)J/Rwdd2aem1(IMPC)J
(C57BL/6NJ-Rwdd2aem1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Rxfp2tm1a(EUCOMM)Wtsi/Rxfp2tm1a(EUCOMM)Wtsi
(C57BL/6N-Rxfp2tm1a(EUCOMM)Wtsi/Ieg)
decreased IgE level J:165965
increased monocyte cell number J:165965
Rxfp4tm1.1(KOMP)Vlcg/Rxfp4tm1.1(KOMP)Vlcg
(C57BL/6N-Rxfp4tm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Rxrapke/Rxrapke
(C57BL/6J-Rxrapke)
abnormal dendritic cell physiology J:103186
abnormal regulatory T cell physiology J:103186
abnormal T-helper 2 cell morphology J:103186
Rxratm1Ipc/Rxratm4Ipc
Rxrbtm1Mma/Rxrbtm1Pcn
Tg(KRT14-cre/ERT2)1Ipc/0

(involves: 129S2/SvPas)
increased immunoglobulin level J:102470
Rxratm1Krc/Rxratm1Krc
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6)
abnormal macrophage activation involved in immune response J:168799
abnormal peritoneal macrophage morphology J:168799
glomerulonephritis J:168799
impaired macrophage phagocytosis J:168799
increased anti-double stranded DNA antibody level J:168799
increased anti-nuclear antigen antibody level J:168799
increased anti-single stranded DNA antibody level J:168799
increased autoantibody level J:168799
increased IgG level J:168799
increased IgM level J:168799
Rxratm2Ipc/Rxratm4Ipc
Tg(KRT14-cre)1Ipc/0

(involves: 129S2/SvPas * C57BL/6 * SJL)
abnormal Langerhans cell morphology J:67149
skin inflammation J:67149
Rxratm4Ipc/Rxratm4Ipc
Rxrbtm1Pcn/Rxrbtm1Pcn
Tg(KRT14-cre/ERT2)1Ipc/0

(involves: 129S2/SvPas)
dermatitis J:102470
ear inflammation J:102470
enlarged cervical lymph nodes J:102470
enlarged spleen J:102470
increased leukocyte cell number J:102470
lymph node hyperplasia J:102470
Rykem1(IMPC)Mbp/Ryk+
(C57BL/6NCrl-Rykem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
Ryr1tm1b(EUCOMM)Hmgu/Ryr1+
(C57BL/6N-Ryr1tm1b(EUCOMM)Hmgu/H)
increased spleen weight J:211773
Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs/Ryr2tm1(CAG-KRAS*G12V,-lacZ)Nobs
Trp53tm1Sia/Trp53tm1Sia

(involves: 129X1/SvJ * C57BL/6 * CBA)
myositis J:117828
Ryr2tm1.1Hnis/Ryr2tm1.1Hnis
(involves: C57BL/6)
abnormal mesenteric lymph node morphology J:228787
abnormal spleen white pulp morphology J:228787
enlarged mesenteric lymph nodes J:228787
immune system phenotype J:228787
increased spleen weight J:228787
increased thymus weight J:228787
large lymphoid organs J:228787
thymus cortex hyperplasia J:228787
S1pr1tm1.1Cys/S1pr1tm1.1Cys
(involves: 129P2/OlaHsd * C3H * C57BL/6)
abnormal B cell physiology J:176118
decreased B cell number J:176118
immune system phenotype J:176118
S1pr1tm1.1Thla/S1pr1tm1.1Thla
(B6.Cg-S1pr1tm1.1Thla)
abnormal leukocyte migration J:163389
abnormal lymphocyte physiology J:163389
increased CD4-positive, alpha-beta T cell number J:163389
increased CD8-positive, alpha-beta T cell number J:163389
S1pr1tm1Cys/S1pr1tm1Cys
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:176118
decreased B cell number J:176118
immune system phenotype J:176118
S1pr1tm1Jch/S1pr1tm1Jch
Tg(GFAP-cre)25Mes/?

(involves: C57BL/6J * FVB/N)
decreased susceptibility to experimental autoimmune encephalomyelitis J:168824
S1pr1tm1Jch/S1pr1tm1Jch
Tg(Nes-cre)1Kln/0

(involves: C57BL/6J * SJL)
decreased susceptibility to experimental autoimmune encephalomyelitis J:168824
S1pr1tm1Jch/S1pr1tm1Jch
Tg(Syn1-cre)671Jxm/?

(involves: C57BL/6J * CBA)
immune system phenotype J:168824
S1pr1tm1Rlp/S1pr1tm1Rlp
(involves: 129S6/SvEvTac)
abnormal NK cell differentiation J:154069
decreased NK cell number J:154069
S1pr1tm3.1(tTA,-Arrb2)Rlp/S1pr1+
Tg(tetO-HIST1H2BJ/GFP)47Efu/0

(involves: 129S6/SvEvTac * C57BL/6 * CD-1 * FVB/N)
immune system phenotype J:212772
S1pr2tm1Ajml/S1pr2tm1Ajml
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal spleen marginal zone morphology J:154439
increased germinal center B cell number J:154439
increased spleen germinal center number J:154439
increased spleen germinal center size J:154439
increased T cell number J:154439
S1pr2tm1Rlp/S1pr2tm1Rlp
(involves: 129S6/SvEvTac * C57BL/6)
abnormal spleen germinal center morphology J:174313
decreased B cell apoptosis J:174313
increased B cell number J:174313
increased B cell proliferation J:174313
increased germinal center B cell number J:174313
increased T cell number J:174313
S1pr3tm1Jch/S1pr3tm1Jch
(involves: 129S1/Sv * 129X1/SvJ)
abnormal cytokine level J:133917
decreased susceptibility to endotoxin shock J:133917
enlarged mesenteric lymph nodes J:133917
S1pr3tm1Rlp/S1pr3tm1Rlp
(involves: 129S6/SvEvTac * C57BL/6)
abnormal B cell physiology J:91161
S1pr4tm1Lipp/S1pr4tm1Lipp
(involves: 129X1/SvJ * C57BL/6J)
abnormal thrombopoiesis J:179199
S1pr5tm1Club/S1pr5tm1Club
(B6.129P2-S1pr5tm1Club)
abnormal NK cell morphology J:178789
abnormal NK cell physiology J:178789
decreased NK cell number J:178789
S1pr5tm1Jch/S1pr5tm1Jch
(involves: 129P2/OlaHsd * C57BL/6)
abnormal NK cell differentiation J:154069
S100a3em1(IMPC)Mbp/S100a3em1(IMPC)Mbp
(C57BL/6NCrl-S100a3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
S100a4tm1.1Abres/S100a4tm1.1Abres
(B6.Cg-S100a4tm1.1Abres)
abnormal eosinophil physiology J:182865
impaired macrophage chemotaxis J:182865
S100a9tm1Hogg/S100a9tm1Hogg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal neutrophil morphology J:82513
abnormal neutrophil physiology J:82513
immune system phenotype J:82513
S100a9tm1Nck/S100a9tm1Nck
(B6.129P2-S100a9tm1Nck)
decreased circulating tumor necrosis factor level J:125179
decreased susceptibility to bacterial infection induced morbidity/mortality J:125179
decreased susceptibility to endotoxin shock J:125179
decreased susceptibility to fungal infection J:209808
S100a9tm1Nck/S100a9tm1Nck
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cellular extravasation J:81642
Saa3tm1(KOMP)Vlcg/Saa3tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
decreased circulating serum amyloid protein level J:220630
Sac3d1tm1Hnaka/Sac3d1+
(involves: 129P2/OlaHsd)
abnormal mast cell physiology J:144601
Sac3d1tm1Hnaka/Sac3d1tm1Hnaka
(involves: 129P2/OlaHsd)
abnormal B cell physiology J:144601
abnormal mast cell physiology J:144601
increased T cell proliferation J:144601
spleen hyperplasia J:144601
thymus hyperplasia J:144601
Sacsem1(IMPC)Tcp/Sacsem1(IMPC)Tcp
(C57BL/6NCrl-Sacsem1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
Sall3tm1.1(KOMP)Mbp/Sall3+
(C57BL/6NCrl-Sall3tm1.1(KOMP)Mbp/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Sall4tm1Brd/Sall4+
(involves: 129S7/SvEvBrd * C57BL/6J)
ear inflammation J:117866
increased susceptibility to otitis media J:117866
Samd3tm1.1(HBEGF)Wfkr/Samd3+
(C57BL/6J-Samd3tm1.1(HBEGF)Wfkr)
abnormal NK cell differentiation J:322359
decreased memory T cell number J:322359
decreased NK cell number J:322359
Samd3tm1.1(HBEGF)Wfkr/Samd3tm1.1(HBEGF)Wfkr
(C57BL/6J-Samd3tm1.1(HBEGF)Wfkr)
decreased CD8-positive, alpha-beta memory T cell number J:322359
immune system phenotype J:322359
Samd8tm1Jia/Samd8tm1Jia
(involves: 129S6/SvEvTac * C57BL/6J)
immune system phenotype J:220024
Samd9ltm1Homy/Samd9l+
(involves: 129P2/OlaHsd)
abnormal myelopoiesis J:202604
abnormal neutrophil morphology J:202604
decreased neutrophil cell number J:202604
enlarged spleen J:202604
increased leukocyte cell number J:202604
increased susceptibility to Retroviridae infection J:202604
Samd9ltm1Homy/Samd9ltm1Homy
(involves: 129P2/OlaHsd)
abnormal myelopoiesis J:202604
abnormal neutrophil morphology J:202604
decreased neutrophil cell number J:202604
enlarged spleen J:202604
increased leukocyte cell number J:202604
increased susceptibility to Retroviridae infection J:202604
Samhd1tm1.2Crs/Samhd1tm1.2Crs
(involves: C57BL/6N * C57BL/6NTac)
increased susceptibility to Retroviridae infection J:201909
Samhd1tm1d(EUCOMM)Wtsi/Samhd1tm1d(EUCOMM)Wtsi
(involves: C57BL/6N)
abnormal response to infection J:202757
immune system phenotype J:202757
Samhd1tm2.2Crs/Samhd1tm2.2Crs
(involves: 129S6/SvEvTac * C57BL/6J)
increased susceptibility to Retroviridae infection J:201909
Samsn1tm1Xyw/Samsn1tm1Xyw
(B6.129P2-Samsn1tm1Xyw)
abnormal dendritic cell physiology J:158032
abnormal T-helper 1 physiology J:158032
abnormal T-helper 2 physiology J:158032
increased B cell proliferation J:158032
increased B-1a cell number J:158032
increased circulating interferon-gamma level J:158032
increased IgG3 level J:158032
increased IgM level J:158032
increased interleukin-4 secretion J:158032
increased interleukin-12 secretion J:158032
increased T cell proliferation J:158032
Sap130tm1a(KOMP)Mbp/Sap130+
(C57BL/6N-Sap130tm1a(KOMP)Mbp/Wtsi)
decreased leukocyte cell number J:211773
Sarm1tm1.1Diam/Sarm1tm1.1Diam
(involves: 129X1/SvJ * C57BL/6)
abnormal circulating tumor necrosis factor level J:200140
decreased microglial cell activation J:200140
immune system phenotype J:200140, J:196200
increased susceptibility to Flaviviridae infection J:200140
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:200140
Sarm1tm1Aidi/Sarm1tm1Aidi
(involves: 129X1/SvJ * C57BL/6J)
immune system phenotype J:126083
Sash3tm1Hlz/Sash3tm1Hlz
(B6.129P2-Sash3tm1Hlz)
abnormal B cell morphology J:102171
abnormal B cell physiology J:102171
abnormal CD4-positive T cell differentiation J:102171
abnormal CD8-positive, alpha-beta T cell differentiation J:102171
abnormal humoral immune response J:102171
abnormal immune system organ morphology J:102171
abnormal inflammatory response J:102171
abnormal marginal zone B cell physiology J:102171
abnormal T cell morphology J:102171
decreased double-positive T cell number J:102171
decreased IgG1 level J:102171
decreased IgG2a level J:102171
decreased IgG level J:102171
decreased IgM level J:102171
decreased interferon-gamma secretion J:102171
decreased interleukin-2 secretion J:102171
decreased interleukin-4 secretion J:102171
decreased interleukin-10 secretion J:102171
decreased marginal zone B cell number J:102171
decreased Peyer's patch number J:102171
decreased T cell proliferation J:102171
decreased tumor necrosis factor secretion J:102171
increased length of allograft survival J:102171
lymphoid hypoplasia J:102171
Satb1m1Anu/Satb1+
(C57L/6JAnu-Satb1m1Anu)
abnormal CD4-positive, alpha beta T cell morphology J:104190
abnormal CD8-positive, alpha beta T cell morphology J:104190
Satb1m1Anu/Satb1m1Anu
(C57L/6JAnu-Satb1m1Anu)
abnormal CD4-positive, alpha beta T cell morphology J:104190
abnormal CD8-positive, alpha beta T cell morphology J:104190
Satb1tm1Kos/Satb1tm1Kos
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:61085
abnormal T cell proliferation J:61085
arrested T cell differentiation J:61085
decreased thymocyte number J:61085
small lymph nodes J:61085
small spleen J:61085
small thymus J:61085
Satb1tm2Kos/Satb1tm2Kos
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
absent regulatory T cells J:252606
increased anti-nuclear antigen antibody level J:252606
increased autoantibody level J:252606
increased susceptibility to autoimmune disorder J:252606
kidney inflammation J:252606
pancreas inflammation J:252606
salivary gland inflammation J:252606
Satb2tm1b(KOMP)Wtsi/Satb2+
(C57BL/6N-Satb2tm1b(KOMP)Wtsi/Ucd)
enlarged lymph nodes J:211773
Saxo1tm1b(EUCOMM)Hmgu/Saxo1tm1b(EUCOMM)Hmgu
(C57BL/6N-Saxo1tm1b(EUCOMM)Hmgu/Ics)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Sbdstm1Dats/Sbdstm1Dats
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

(involves: C57BL/6 * CD-1)
abnormal myeloid leukocyte morphology J:158901
abnormal neutrophil morphology J:158901
decreased B cell number J:158901
decreased leukocyte cell number J:158901
decreased lymphocyte cell number J:158901
Sbf1em1(IMPC)Mbp/Sbf1em1(IMPC)Mbp
(C57BL/6N-Sbf1em1(IMPC)Mbp/MbpMmucd)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Sbno1tm1b(EUCOMM)Hmgu/Sbno1+
(C57BL/6N-Sbno1tm1b(EUCOMM)Hmgu/H)
increased leukocyte cell number J:211773
Sbno2tm1.1Aki/Sbno2tm1.1Aki
(involves: 129 * C57BL/6)
abnormal osteoclast morphology J:202853
abnormal osteoclast physiology J:202853
immune system phenotype J:202853
Sbsnem1Ham/Sbsnem1Ham
(C57BL/6N-Sbsnem1Ham)
decreased interleukin-4 secretion J:296400
decreased susceptibility to type IV hypersensitivity reaction J:296400
immune system phenotype J:296400
increased susceptibility to type IV hypersensitivity reaction J:296400
Sbw1NZB/BlScr/Sbw1NZB/BlScr
(involves: NZB/BlScr * NZW/LacScr)
enlarged spleen J:20991
Sbw2NZB/BlScr/Sbw2NZB/BlScr
(involves: NZB * NZW)
enlarged spleen J:20991
Sbw2NZB/BlScr/Sbw2NZW/LacScr
(involves: NZB * NZW)
enlarged spleen J:20991
Scaitm1b(EUCOMM)Hmgu/Scaitm1b(EUCOMM)Hmgu
(involves: C57BL/6N * FVB/N)
immune system phenotype J:240463
Scand1em1(IMPC)H/Scand1em1(IMPC)H
(C57BL/6NTac-Scand1em1(IMPC)H/H)
decreased spleen weight J:211773
Scara5tm1Ktry/Scara5tm1Ktry
(B6N.129X1-Scara5tm1Ktry)
adipose tissue inflammation J:195536
increased anti-nuclear antigen antibody level J:195536
interstitial pneumonia J:195536
liver inflammation J:195536
lung inflammation J:195536
skin inflammation J:195536
urinary bladder inflammation J:195536
Scarb1tm1.1Thh/Scarb1tm1.1Thh
(B6.129X1-Scarb1tm1.1Thh)
increased circulating interleukin-6 level J:114663
Scarb1tm1b(EUCOMM)Wtsi/Scarb1tm1b(EUCOMM)Wtsi
(C57BL/6N-Scarb1tm1b(EUCOMM)Wtsi/Bay)
enlarged spleen J:211773
increased spleen weight J:211773
Scarb1tm1Thh/Scarb1tm1Thh
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(B6.Cg-Scarb1tm1Thh Speer6-ps1Tg(Alb-cre)21Mgn)
increased circulating interleukin-6 level J:114663
Scarb2em2(IMPC)Tcp/Scarb2em2(IMPC)Tcp
(C57BL/6NCrl-Scarb2em2(IMPC)Tcp/Tcp)
decreased monocyte cell number J:211773
enlarged lymph nodes J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Scarb2tm1Psa/Scarb2tm1Psa
(involves: 129P2/OlaHsd * C57BL/6N)
microgliosis J:216676
Scarf1tm1Tkms/Scarf1tm1Tkms
(involves: C57BL/6)
abnormal B cell physiology J:208237
abnormal dendritic cell physiology J:208237
abnormal spleen morphology J:208237
enlarged spleen J:208237
glomerulonephritis J:208237
immune system phenotype J:208237
impaired macrophage phagocytosis J:208237
increased anti-histone antibody level J:208237
increased anti-nuclear antigen antibody level J:208237
increased anti-single stranded DNA antibody level J:208237
increased B cell number J:208237
increased CD4-positive, alpha-beta T cell number J:208237
increased IgG level J:208237
increased lymphocyte cell number J:208237
increased spleen germinal center size J:208237
increased susceptibility to systemic lupus erythematosus J:208237
increased T follicular helper cell number J:208237
skin inflammation J:208237
Scd1ab-2J/Scd1ab-2J
(DBA/1LacJ-Scd1ab-2J/J)
granulomatous inflammation J:62699
Scd1flk/Scd1flk
(C57BL/6J-Scd1flk)
increased susceptibility to bacterial infection J:100424
Scd2swty/Scd2swty
(C57BL/6JSfdAnu-Scd2swty/Anu)
blepharitis J:104190
Scelem1(IMPC)Ccpcz/Scelem1(IMPC)Ccpcz
(C57BL/6NCrl-Scelem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Scg5em1(IMPC)Mbp/Scg5em1(IMPC)Mbp
(C57BL/6NCrl-Scg5em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased monocyte cell number J:211773
Scg5tm1Led/Scg5tm1Led
(either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * FVB) or (involves: 129S6/SvEvTac * C57BL/6))
spleen atrophy J:53349
Scgb1a1tm1Abm/Scgb1a1+
(involves: 129S1/Sv * 129X1/SvJ)
abnormal complement protein level J:57504
increased IgA level J:57504
Scgb1a1tm1Abm/Scgb1a1tm1Abm
(involves: 129S1/Sv * 129X1/SvJ)
abnormal complement protein level J:57504
increased IgA level J:57504
Scgnem1Ezb/Scgnem1Ezb
(C57BL/6-Scgnem1Ezb)
increased susceptibility to colitis induced morbidity/mortality J:285572
Scgnem2Ezb/Scgnem2Ezb
(C57BL/6-Scgnem2Ezb)
increased susceptibility to colitis induced morbidity/mortality J:285572
Scintm1Glog/Scintm1Glog
Tg(Acp5-cre)4Rda/0

(either: (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * CBA))
abnormal osteoclast differentiation J:223220
abnormal osteoclast morphology J:223220
abnormal osteoclast physiology J:223220
Scl2C57BL/6J/Scl2C57BL/6J
(involves: C57BL/6J * DBA/2J)
increased susceptibility to parasitic infection J:12046
Scmh1tm1Yota/Scmh1tm1Yota
(involves: 129X1/SvJ * C57BL/6)
decreased B cell number J:194424
decreased T cell number J:194424
myeloid hyperplasia J:194424
Scml4em1(IMPC)J/Scml4em1(IMPC)J
(C57BL/6NJ-Scml4em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Scn3btm1a(KOMP)Wtsi/Scn3btm1a(KOMP)Wtsi
(C57BL/6N-Scn3btm1a(KOMP)Wtsi/Wtsi)
myositis J:232539
Scn8aem1(IMPC)Bay/Scn8a+
(C57BL/6N-Scn8aem1(IMPC)Bay/BayMmucd)
increased spleen weight J:211773
Scn9atm1Dgen/Scn9atm1Dgen
(either: (involves: 129P2/OlaHsd * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6 * CD-1))
dermatitis J:223425
Sco1tm1c(KOMP)Wtsi/Sco1tm1c(KOMP)Wtsi
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: C57BL/6 * C57BL/6N * DBA)
decreased leukocyte cell number J:222036
decreased spleen white pulp amount J:222036
increased spleen iron level J:222036
spleen atrophy J:222036
Scp2tm1Kier/Scp2tm1Kier
(involves: 129P2/OlaHsd * C57BL/6NCr)
liver inflammation J:124895
Scr/Scr
(involves: 101/H * C3H/HeH)
small thymus J:3458
Sctrtm1Bkcc/Sctrtm1Bkcc
(B6.129S7-Sctrtm1Bkcc)
abnormal cytokine secretion J:121376
increased macrophage cell number J:121376
kidney inflammation J:121376
Scyl1tm1.1Spel/Scyl1tm1.1Spel
(involves: 129S6/SvEvTac * C57BL/6J)
microgliosis J:192445
Scyl1tm1Spel/Scyl1tm1Spel
Tg(Nes-cre)1Kln/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL)
microgliosis J:192445
Scyl2tm1.1Spel/Scyl2tm1.1Spel
Tg(Nes-cre)1Kln/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
microgliosis J:225808
Scyl3tm1.1Spel/Scyl3tm1.1Spel
(involves: 129S6/SvEvTac * C57BL/6J)
immune system phenotype J:262629
Sdc1tm1Cma/Sdc1tm1Cma
(either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6))
decreased susceptibility to bacterial infection J:69845
Sdc1tm1Cma/Sdc1tm1Cma
(either: C.Cg-Sdc1tm1Cma or B6.Cg-Sdc1tm1Cma)
increased inflammatory response J:80682
Sdc1tm1Cma/Sdc1tm1Cma
(B6.Cg-Sdc1tm1Cma)
decreased susceptibility to bacterial infection J:104294
decreased susceptibility to bacterial infection induced morbidity/mortality J:104294
Sdc1tm1Cma/Sdc1tm1Cma
(involves: 129S4/SvJae)
decreased IgG1 level J:107378
decreased interleukin-10 secretion J:107378
decreased interleukin-13 secretion J:107378
increased susceptibility to parasitic infection J:107378
Sdc4tm2b(KOMP)Wtsi/Sdc4tm2b(KOMP)Wtsi
(C57BL/6N-Sdc4tm2b(KOMP)Wtsi/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Sdhbtm1b(EUCOMM)Hmgu/Sdhb+
(C57BL/6N-Sdhbtm1b(EUCOMM)Hmgu/Ieg)
decreased neutrophil cell number J:211773
seb/seb
(Him:OF1)
dermatitis J:64455
lymph node hyperplasia J:20987
lymph node inflammation J:20987
skin inflammation J:8983
Sec1em1Cya/Sec1em1Cya
(C57BL/6-Sec1em1Cya)
decreased susceptibility to bacterial infection induced morbidity/mortality J:325740
Sec22btm1c(EUCOMM)Wtsi/Sec22btm1c(EUCOMM)Wtsi
Tg(Itgax-cre)1-1Reiz/0

(involves: C57BL/6 * C57BL/6N * CBA * SJL)
immune system phenotype J:255769
Sec23bGt(AD0407)Wtsi/Sec23bGt(AD0407)Wtsi
(B6J.129P2-Sec23bGt(AD0407)Wtsi)
pancreas inflammation J:186391
Sec24bem1(IMPC)Tcp/Sec24b+
(C57BL/6NCrl-Sec24bem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Sec63tm1b(EUCOMM)Hmgu/Sec63+
(C57BL/6N-Sec63tm1b(EUCOMM)Hmgu/Bay)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Secia1DBA/1J/?
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:123131
Secia2DBA/1J/?
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:123131
Secia3FVB/NJ/?
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:123131
Secia4DBA/1J/?
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:123131
Secia5DBA/1J/?
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:123131
Secia6DBA/1J/?
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:123131
Secia7FVB/NJ/?
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:123131
Secia8FVB/NJ/?
(involves: DBA/1J * FVB/NJ)
increased susceptibility to induced arthritis J:123131
Secisbp2tm1a(EUCOMM)Wtsi/Secisbp2+
(Not Specified)
increased NK cell number J:165965
Secisbp2tm1c(EUCOMM)Wtsi/Secisbp2tm1c(EUCOMM)Wtsi
(C57BL/6N-Secisbp2tm1a(EUCOMM)Wtsi/H)
increased leukocyte cell number J:211773
Sectm1aem1Gcfa/Sectm1aem1Gcfa
(C57BL/6-Sectm1aem1Gcfa)
abnormal interleukin level J:317204
abnormal macrophage physiology J:317204
abnormal tumor necrosis factor level J:317204
heart inflammation J:317204
increased circulating interleukin-1 beta level J:317204
increased circulating interleukin-6 level J:317204
increased circulating tumor necrosis factor level J:317204
increased susceptibility to endotoxin shock J:317204
Seletm1Alb/Seletm1Alb
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal spleen morphology J:101979
eye inflammation J:101979
increased susceptibility to bacterial infection J:101979
Seletm1Alb/Seletm1Alb
(involves: 129S7/SvEvBrd * C57BL/6)
increased neutrophil cell number J:112286
Seletm1Dmil/Seletm1Dmil
(involves: 129S4/SvJae * C57BL/6J)
abnormal leukocyte adhesion J:113169
Seletm1Hyn/Seletm1Hyn
Selltm1Hyn/Selltm1Hyn
Selptm1Hyn/Selptm1Hyn

(involves: 129S2/SvPas * C57BL/6)
impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased leukocyte cell number J:57973
increased monocyte cell number J:57973
increased neutrophil cell number J:57973
Seletm1Hyn/Seletm1Hyn
Selptm1Hyn/Selptm1Hyn

(involves: 129S2/SvPas)
abnormal cytokine level J:31626
abnormal granulocyte differentiation J:31626
abnormal myelopoiesis J:31626
impaired leukocyte tethering or rolling J:31626
impaired neutrophil recruitment J:31626
increased circulating interleukin-3 level J:31626
increased eosinophil cell number J:31626
increased leukocyte cell number J:31626
increased lymphocyte cell number J:31626
increased monocyte cell number J:31626
increased neutrophil cell number J:31626
increased spleen red pulp amount J:31626
increased spleen weight J:31626
increased susceptibility to bacterial infection J:31626
spleen hyperplasia J:31626
Seletm1Hyn/Seletm1Hyn
Selptm1Hyn/Selptm1Hyn

(involves: 129S2/SvPas * C57BL/6)
impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased leukocyte cell number J:57973
increased monocyte cell number J:57973
increased neutrophil cell number J:57973
Seletm1Roml/Seletm1Roml
(involves: 129S1/Sv * C57BL/6)
abnormal T cell physiology J:113536
Seletm1Roml/Seletm1Roml
(involves: 129S1/Sv)
abnormal T cell physiology J:113536
Seletm2Alb/Seletm2Alb
Selltm2Alb/Selltm2Alb
Selptm1Bay/Selptm1Bay

(involves: 129S7/SvEvBrd * C57BL/6)
abnormal cellular extravasation J:70682
abnormal cervical lymph node morphology J:70682
abnormal spleen B cell follicle morphology J:70682
abnormal spleen B cell follicle shape J:106550
abnormal spleen morphology J:70682
decreased spleen B cell follicle number J:106550
enlarged lymph nodes J:70682
immune system phenotype J:70682
impaired leukocyte tethering or rolling J:70682
increased eosinophil cell number J:70682
increased leukocyte cell number J:70682
increased monocyte cell number J:70682
increased neutrophil cell number J:106550, J:70682
lung inflammation J:70682
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay

(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal leukocyte cell number J:101979
eye inflammation J:101979
increased neutrophil cell number J:101979
increased susceptibility to bacterial infection J:101979
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay

(involves: 129S7/SvEvBrd * C57BL/6)
abnormal cytokine secretion J:70682
abnormal lymph node germinal center morphology J:70682
abnormal lymph node secondary follicle morphology J:70682
abnormal neutrophil physiology J:112286
abnormal spleen B cell follicle morphology J:70682
decreased acute inflammation J:112286
decreased spleen B cell follicle number J:70682
enlarged lymph nodes J:70682
impaired leukocyte tethering or rolling J:70682
increased eosinophil cell number J:70682
increased leukocyte cell number J:70682
increased monocyte cell number J:70682
increased neutrophil cell number J:70682, J:112286
Seletm2Hyn/Seletm2Hyn
(involves: 129S2/SvPas * C57BL/6)
enhanced leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
Seletm2Hyn/Seletm2Hyn
(B6.129S2-Seletm2Hyn)
abnormal type IV hypersensitivity reaction J:121083
decreased mast cell number J:121083
increased mast cell number J:121083
Selenbp1tm1Hyama/Selenbp1tm1Hyama
(C57BL/6-Selenbp1tm1Hyama)
decreased spleen weight J:202420
increased thymus weight J:202420
Selenoktm1.2Itl/Selenoktm1.2Itl
(involves: BALB/cJ * C57BL/6)
abnormal circulating chemokine level J:169169
abnormal macrophage physiology J:169169
abnormal neutrophil physiology J:169169
abnormal T cell physiology J:169169
decreased interleukin-6 secretion J:169169
decreased T cell proliferation J:169169
decreased tumor necrosis factor secretion J:169169
impaired neutrophil chemotaxis J:169169
increased susceptibility to Flaviviridae infection J:169169
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:169169
Selenoptm1Rfb/Selenoptm1Rfb
(B6.129-Selenoptm1Rfb)
increased susceptibility to parasitic infection J:134536
Selenowem#Hwl/Selenowem#Hwl
(C57BL/6-Selenowem#Hwl)
abnormal osteoclast differentiation J:317012
decreased osteoclast cell number J:317012
Sellm1Btlr/Sellm1Btlr
(C57BL/6J-Sellm1Btlr)
decreased single-positive T cell number J:217794
Sellm2Btlr/Sellm2Btlr
(C57BL/6J-Sellm2Btlr)
decreased response to antigen J:231806
decreased single-positive T cell number J:231806
Selltm1.1Rpmc/Selltm1.1Rpmc
(involves: 129S1/Sv * C57BL/6J * FVB/N)
abnormal granulocyte physiology J:249558
abnormal neutrophil physiology J:249558
immune system phenotype J:249558
increased inflammatory response J:249558
Selltm1Alb/Selltm1Alb
(involves: 129S7/SvEvBrd * C57BL/6)
intermingled spleen red and white pulp J:70682
Selltm1b(EUCOMM)Hmgu/Selltm1b(EUCOMM)Hmgu
(C57BL/6N-Selltm1b(EUCOMM)Hmgu/H)
increased spleen weight J:211773
Selltm1Flv/Sell+
(involves: C57BL/6 * NOD)
decreased susceptibility to autoimmune diabetes J:88947
pancreas inflammation J:88947
Selltm1Flv/Sell+
(NOD.Cg-Selltm1Flv)
immune system phenotype J:88974
Selltm1Flv/Selltm1Flv
(involves: 129S2/SvPas * C57BL/6)
abnormal type IV hypersensitivity reaction J:89253
decreased activated T cell number J:89253
Selltm1Flv/Selltm1Flv
(involves: C57BL/6 * NOD)
decreased susceptibility to autoimmune disorder J:88947
pancreas inflammation J:88947
Selltm1Flv/Selltm1Flv
(NOD.Cg-Selltm1Flv)
immune system phenotype J:88974
Selltm1Pest/Sell+
(involves: 129S4/SvJae * C57BL/6)
abnormal hypersensitivity reaction J:112550
impaired leukocyte tethering or rolling J:112550
Selltm1Pest/Selltm1Pest
(involves: 129S4/SvJae)
abnormal hypersensitivity reaction J:111233
abnormal leukocyte adhesion J:111233
impaired leukocyte tethering or rolling J:111233
increased T cell proliferation J:111233
Selltm1Pest/Selltm1Pest
(involves: 129S4/SvJae * C57BL/6)
abnormal cell-mediated immunity J:112550
abnormal dendritic cell physiology J:112550
abnormal hypersensitivity reaction J:112550
abnormal leukocyte migration J:112550
abnormal splenic cell ratio J:112550
decreased T cell proliferation J:112550
enlarged spleen J:112550
immune system phenotype J:112550
impaired leukocyte tethering or rolling J:112550
lymph node hypoplasia J:112550
small popliteal lymph nodes J:112550
Selltm1Tft/Selltm1Tft
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cellular extravasation J:25005
abnormal leukocyte migration J:25005
enlarged spleen J:25005
impaired leukocyte tethering or rolling J:25005
Selltm1Tft/Selltm1Tft
(B6.129-Selltm1Tft)
abnormal cellular extravasation J:66107
abnormal leukocyte migration J:66107
Selltm1Tft/Selltm1Tft
(B6.129P2-Selltm1Tft)
abnormal cellular extravasation J:48271
abnormal regulatory T cell number J:141931
abnormal regulatory T cell physiology J:141931
impaired leukocyte tethering or rolling J:48271
increased monocyte cell number J:48271, J:142184
lymph node hypoplasia J:141931, J:142184
spleen hyperplasia J:141931
Selltm2.1Tft/Selltm2.1Tft
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal neutrophil physiology J:142184
spleen hyperplasia J:142184
Selltm2Hyn/Selltm2Hyn
(involves: 129S2/SvPas * C57BL/6)
decreased monocyte cell number J:57973
immune system phenotype J:106550
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
Selltm2Hyn/Selltm2Hyn
(involves: 129S2/SvPas * BALB/c)
impaired leukocyte tethering or rolling J:114317
Selltm2Tft/Selltm2.1Tft
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal leukocyte migration J:142184
abnormal neutrophil physiology J:142184
abnormal regulatory T cell number J:141931
abnormal regulatory T cell physiology J:141931
impaired leukocyte tethering or rolling J:142184
Selltm2Tft/Selltm2Tft
(involves: 129S1/Sv * 129X1/SvJ)
lymph node hypoplasia J:142184
spleen hyperplasia J:142184
Selltm3Hyn/Selltm3Hyn
Selptm1Hyn/Selptm1Hyn

(involves: 129S2/SvPas * C57BL/6)
impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased leukocyte cell number J:57973
increased neutrophil cell number J:57973
Selltm4Hyn/Selltm4Hyn
Selptm1Hyn/Selptm1Hyn

(involves: 129S2/SvPas * C57BL/6)
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
Selptm1.1Rpmc/Selptm1.1Rpmc
(B6.129S1-Selptm1.1Rpmc)
impaired leukocyte tethering or rolling J:230041
Selptm1Bay/Selptm1Bay
(involves: 129S7/SvEvBrd * C57BL/6J)
abnormal leukocyte migration J:24239
abnormal spleen morphology J:101979
eye inflammation J:101979
increased leukocyte cell number J:101979
increased neutrophil cell number J:101979, J:24239
increased susceptibility to bacterial infection J:101979
Selptm1Bay/Selptm1Bay
(D1.129S7(B6J)-Selptm1Bay)
abnormal cytokine secretion J:57086
increased IgG level J:57086
increased susceptibility to induced arthritis J:57086
Selptm1Bay/Selptm1Bay
(B6.129S7-Selptm1Bay/J)
abnormal T cell physiology J:113536
Selptm1Bay/Selptm1Bay
(either: B6.129S7-Selptm1Bay or (involves: 129S7/SvEvBrd * C57BL/6))
abnormal leukocyte tethering or rolling J:31374
increased leukocyte cell number J:31374
Selptm1Bay/Selptm1Bay
(involves: 129S7/SvEvBrd * C57BL/6)
increased neutrophil cell number J:112286
Selptm1Bay/Selptm1Bay
(B6.129S7-Selptm1Bay)
decreased mast cell number J:121083
decreased susceptibility to type IV hypersensitivity reaction J:121083
Selptm1Hyn/Selptm1Hyn
(involves: 129S2/SvPas * C57BL/6J)
impaired leukocyte tethering or rolling J:77329
impaired neutrophil recruitment J:77329
increased neutrophil cell number J:77329
Selptm1Hyn/Selptm1Hyn
(involves: 129S2/SvPas)
impaired leukocyte tethering or rolling J:29814
impaired macrophage chemotaxis J:29814
increased neutrophil cell number J:29814
Selptm1Hyn/Selptm1Hyn
(involves: 129S2/SvPas * C57BL/6)
impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased neutrophil cell number J:57973
Selptm2Hyn/Selptm2Hyn
(involves: 129S2/SvPas * C57BL/6J)
impaired leukocyte tethering or rolling J:51068
impaired neutrophil recruitment J:51068
Selplgtm1Fur/Selplgtm1Fur
(involves: 129/Sv * C57BL/6J * SJL)
impaired leukocyte tethering or rolling J:75412
impaired neutrophil chemotaxis J:75412
increased eosinophil cell number J:75412
increased neutrophil cell number J:75412
Selplgtm1Rpmc/Selplgtm1Rpmc
(involves: 129S1/Sv * C57BL/6J)
abnormal leukocyte adhesion J:75829
impaired leukocyte tethering or rolling J:75829, J:138731
increased eosinophil cell number J:75829
increased leukocyte cell number J:75829
increased lymphocyte cell number J:75829
increased neutrophil cell number J:75829
Selplgtm1Rpmc/Selplgtm1Rpmc
(involves: 129S1/Sv)
abnormal chemokine secretion J:115682
immune system phenotype J:115682
Selplgtm2Rpmc/Selplgtm2Rpmc
(B6.Cg-Selplgtm2Rpmc)
impaired leukocyte tethering or rolling J:138731
Sema3atm1.1Tyag/Sema3atm1.1Tyag
(involves: C57BL/6 * CBA)
abnormal dendritic cell physiology J:161856
abnormal T cell physiology J:161856
Sema3ftm1.2Ddg/Sema3ftm1.2Ddg
(Not Specified)
abnormal lymphatic system physiology J:226501
abnormal lymphatic vessel endothelial cell morphology J:226501
abnormal lymphatic vessel morphology J:226501
Sema3ftm1.2Ddg/Sema3ftm1.2Ddg
Sema3gtm1(KOMP)Vlcg/Sema3gtm1(KOMP)Vlcg

(involves: C57BL/6NTac)
abnormal lymphatic vessel endothelial cell morphology J:226501
abnormal lymphatic vessel morphology J:226501
lymphatic vessel hyperplasia J:226501
Sema3gtm1(KOMP)Vlcg/Sema3gtm1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal lymphatic vessel morphology J:226501
Sema4atm1Kik/Sema4atm1Kik
(either: B6.Cg-Sema4atm1Kik or C.Cg-Sema4atm1Kik)
abnormal CD4-positive, alpha-beta T cell physiology J:97027
abnormal cytokine secretion J:97027
abnormal dendritic cell antigen presentation J:97027
abnormal T-helper 1 cell differentiation J:97027
decreased susceptibility to type IV hypersensitivity reaction J:97027
Sema4btm1Akum/Sema4btm1Akum
(either: B6.Cg-Sema4btm1Akum or C.Cg-Sema4btm1Akum)
abnormal immune system physiology J:169386
increased IgE level J:169386
increased IgG1 level J:169386
Sema4dtm1b(EUCOMM)Wtsi/Sema4dtm1b(EUCOMM)Wtsi
(C57BL/6N-Sema4dtm1b(EUCOMM)Wtsi/H)
enlarged spleen J:211773
Sema4dtm1Kik/Sema4dtm1Kik
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B-1 B cell morphology J:66033
abnormal immunoglobulin level J:66033
decreased B cell proliferation J:66033
decreased B-1a cell number J:66033
decreased CD4-positive, alpha-beta T cell number J:66033
decreased spleen germinal center size J:66033
decreased T cell number J:66033
increased B cell number J:66033
Sema5btm1a(EUCOMM)Wtsi/Sema5btm1a(EUCOMM)Wtsi
(C57BL/6N-Sema5btm1a(EUCOMM)Wtsi/Cnrm)
decreased T cell number J:165965
Sema6ctm1Matl/Sema6ctm1Matl
(Not Specified)
immune system phenotype J:161856
Sema6dtm1Kik/Sema6dtm1Kik
(Not Specified)
immune system phenotype J:161856
Senp1tm1.1Wami/Senp1tm1.1Wami
(involves: 129 * C57BL/6)
abnormal granulocyte differentiation J:163428
abnormal monocyte differentiation J:163428
Senp1tm1Wami/Senp1tm1Wami
Tg(Fabp4-cre)#Abel/0

(B6.Cg-Senp1tm1Wami Tg(Fabp4-cre)#Abel)
abnormal chemokine level J:228009
abnormal circulating cytokine level J:228009
abnormal cytokine level J:228009
increased anti-insulin autoantibody level J:228009
increased circulating C-reactive protein level J:228009
increased circulating interleukin-1 beta level J:228009
increased circulating interleukin-6 level J:228009
increased circulating tumor necrosis factor level J:228009
increased susceptibility to autoimmune diabetes J:228009
myocarditis J:228009
pancreas inflammation J:228009
Septin5tm1b(EUCOMM)Hmgu/Septin5+
(C57BL/6N-Septin5tm1b(EUCOMM)Hmgu/Rbrc)
small spleen J:211773
Septin7tm1Mgl/Septin7tm1Mgl
Tg(CD2-icre)4Kio/0

(involves: 129P2/OlaHsd * C3H * C57BL/6 * C57BL/10 * CBA/Ca)
immune system phenotype J:223786
Septin9tm2.1Emfu/Septin9tm2.1Emfu
Tg(Lck-cre)548Jxm/0

(involves: C57BL/6 * CBA)
abnormal T cell differentiation J:205027
decreased CD4-positive, alpha-beta memory T cell number J:205027
decreased CD4-positive, alpha-beta T cell number J:205027
decreased CD8-positive, alpha-beta memory T cell number J:205027
decreased CD8-positive, alpha-beta T cell number J:205027
decreased DN4 thymocyte number J:205027
decreased regulatory T cell number J:205027
decreased single-positive T cell number J:205027
decreased T cell number J:205027
decreased T cell proliferation J:205027
increased CD8-positive, alpha-beta memory T cell number J:205027
increased DN3 thymocyte number J:205027
increased double-negative T cell number J:205027
Septin9tm2.1Emfu/Septin9tm2.1Emfu
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
decreased CD8-positive, alpha-beta T cell number J:205027
Serac1em1(IMPC)Tcp/Serac1em1(IMPC)Tcp
(C57BL/6NCrl-Serac1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Serf1tm1a(EUCOMM)Hmgu/Serf1tm1a(EUCOMM)Hmgu
(C57BL/6N-Serf1tm1a(EUCOMM)Hmgu/H)
decreased CD8-positive, alpha-beta T cell number J:165965
decreased T cell number J:165965
Serinc5em1Spst/Serinc5em1Spst
(C57BL/6-Serinc5em1Spst)
immune system phenotype J:291232
Serpina1em#Chmu/Serpina1em#Chmu
(involves: C57BL/6J)
increased susceptibility to endotoxin shock J:259615
respiratory system inflammation J:259615
Serpina3cem1Smoc/Serpina3cem1Smoc
(C57BL/6-Serpina3cem1Smoc)
white adipose tissue inflammation J:343846
Serpina3gtm1.1Arp/Serpina3gtm1.1Arp
(involves: C57BL/6)
abnormal memory T cell morphology J:189782
abnormal response to infection J:189782
decreased CD8-positive, alpha-beta memory T cell number J:189782
decreased T cell proliferation J:189782
Serpina3gtm1.1Arp/Serpina3gtm1.1Arp
Tg(TcrLCMV)#Sdz/0

(involves: C57BL/6 * DBA/2)
decreased T cell proliferation J:189782
Serpina3iem1(IMPC)J/Serpina3iem1(IMPC)J
(C57BL/6NJ-Serpina3iem1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Serpina6tm1Tew/Serpina6tm1Tew
(involves: 129/SvEmcTer * C57BL/6N)
abnormal circulating cytokine level J:112974
abnormal cytokine level J:112974
increased susceptibility to endotoxin shock J:112974
Serpinb1atm1.1Cben/Serpinb1atm1.1Cben
(129S6/SvEvTac-Serpinb1atm1.1Cben)
abnormal chemokine secretion J:125918
abnormal circulating cytokine level J:125918
abnormal neutrophil physiology J:125918
decreased neutrophil cell number J:125918
impaired neutrophil chemotaxis J:125918
increased interleukin-1 beta secretion J:125918
increased susceptibility to bacterial infection J:125918
increased susceptibility to bacterial infection induced morbidity/mortality J:125918
increased tumor necrosis factor secretion J:125918
lung inflammation J:125918
sepsis J:125918
Serpinb2tm1Dgi/Serpinb2tm1Dgi
(involves: 129S2/SvPas * C57BL/6J * DBA/2J)
abnormal leukocyte cell number J:52283
decreased lymphocyte cell number J:52283
decreased monocyte cell number J:52283
decreased neutrophil cell number J:52283
immune system phenotype J:52283
Serpinb2tm2Dgi/Serpinb2tm2Dgi
(involves: 129S2/SvPas * C57BL/6J * DBA/2J)
abnormal leukocyte cell number J:52283
decreased lymphocyte cell number J:52283
decreased monocyte cell number J:52283
decreased neutrophil cell number J:52283
immune system phenotype J:52283
Serpinb3atm1Gsil/Serpinb3atm1Gsil
(C.129-Serpinb3atm1Gsil)
decreased susceptibility to type I hypersensitivity reaction J:189949
Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
(involves: BALB/cJ * C57BL/6J)
abnormal dendritic cell antigen presentation J:252016
abnormal immune system morphology J:252016
abnormal immune system physiology J:252016
decreased cytotoxic T cell apoptosis J:252016
immune system phenotype J:252016
Serpinb9tm1Arp/Serpinb9tm1Arp
(involves: C57BL/6)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:113349
abnormal cytotoxic T cell physiology J:113349
decreased cytotoxic T cell cytolysis J:113349
increased susceptibility to Riboviria infection J:113349
Serpinb9tm1Arp/Serpinb9tm1Arp
Tg(TcrLCMV)327Sdz/0

(involves: C57BL/6)
abnormal response to transplant J:113349
Serpinb10em1(IMPC)Mbp/Serpinb10em1(IMPC)Mbp
(C57BL/6NCrl-Serpinb10em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Serpinc1tm1Dwr/Serpinc1tm1Dwr
(involves: 129S1/Sv * 129X1/SvJ)
enlarged spleen J:115658
liver inflammation J:115658
Serpine1em1(IMPC)Tcp/Serpine1em1(IMPC)Tcp
(C57BL/6N-Serpine1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Serpine1tm1.1Vlp/Serpine1tm1.1Vlp
(involves: 129 * C57BL/6)
decreased susceptibility to endotoxin shock J:229191
Serpine1tm1Mlg/Serpine1tm1Mlg
(involves: 129S2/SvPas * C57BL/6)
abnormal acute inflammation J:133227
abnormal interleukin level J:133227
decreased circulating interleukin-6 level J:133227
glomerulonephritis J:85989
immune system phenotype J:133227
increased acute inflammation J:133227
increased granulocyte number J:133227
respiratory system inflammation J:66093
Serpine1tm1Mlg/Serpine1tm1Mlg
(B6.129S2-Serpine1tm1Mlg/J)
heart inflammation J:101486
increased susceptibility to bacterial infection J:124327
increased susceptibility to Coronaviridae infection J:288556
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:288556
Serpine1tm1Mlg/Serpine1tm1Mlg
(involves: 129S2/SvPas)
decreased susceptibility to endotoxin shock J:229191
Serpine2tm1Dmn/Serpine2tm1Dmn
(B6.129P2-Serpine2tm1Dmn)
abnormal acute phase protein level J:121263
Serpinf1tm1e.1(KOMP)Wtsi/Serpinf1tm1e.1(KOMP)Wtsi
(C57BL/6N-Serpinf1tm1e.1(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
Serpini2pq/Serpini2pq
(involves: C57BL/6J)
abnormal B cell differentiation J:115744
abnormal pre-B cell morphology J:115744
abnormal pro-B cell morphology J:115744
decreased B cell number J:115744
decreased immature B cell number J:115744
decreased lymphocyte cell number J:115744
decreased pre-B cell number J:115744
decreased pro-B cell number J:115744
decreased T cell number J:115744
decreased thymocyte number J:115744
small spleen J:115744
small thymus J:115744
spleen hypoplasia J:115744
thymus hypoplasia J:115744
Sertad2Gt(OST98734)Lex/Sertad2Gt(OST98734)Lex
(B6.129S5-Sertad2Gt(OST98734)Lex)
abnormal macrophage physiology J:194928
Sertad3em1Bcgen/Sertad3em1Bcgen
(involves: C57BL/6N)
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:300469
Ses1aC57BL/6J/Ses1aC57BL/6J
(involves: 129 * C57BL/6J)
decreased susceptibility to bacterial infection J:81412
Ses1aC57BL/6J/Ses1aC57BL/6J
(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses1aC57BL/6J/Ses1aC57BL/6J
(129.B6-Ses1aC57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses1aC57BL/6J/Ses1aC57BL/6J
Ses4C57BL/6J/Ses4C57BL/6J

(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses1aC57BL/6J/Ses1aC57BL/6J
Ses5C57BL/6J/Ses5C57BL/6J

(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses1aC57BL/6J/Ses1aC57BL/6J
Ses6C57BL/6J/Ses6C57BL/6J

(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses1bC57BL/6J/Ses1bC57BL/6J
(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses1bC57BL/6J/Ses1bC57BL/6J
(129.B6-Ses1bC57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses2C57BL/6J/Ses2C57BL/6J
(involves: 129 * C57BL/6J)
decreased susceptibility to bacterial infection J:81412
Ses3C57BL/6J/Ses3C57BL/6J
(involves: 129 * C57BL/6J)
decreased susceptibility to bacterial infection J:81412
Ses7129S6/SvEvTac/Ses7C57BL/6J
Ses8C57BL/6J/Ses8C57BL/6J

(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses7C57BL/6J/Ses7C57BL/6J
Ses8C57BL/6J/Ses8C57BL/6J

(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to bacterial infection J:100367
Ses9C57BL/6J/Ses9C57BL/6J
Ses10C57BL/6J/Ses10C57BL/6J

(involves: 129S6/SvEvTac * C57BL/6J)
decreased susceptibility to bacterial infection J:100367
Sesn1tm1a(EUCOMM)Wtsi/Sesn1tm1a(EUCOMM)Wtsi
(involves: C57BL/6N)
abnormal class switch recombination J:240602
abnormal effector T cell number J:240602
decreased B cell number J:240602
enlarged spleen J:240602
increased immunoglobulin level J:240602
increased interferon-gamma secretion J:240602
increased interleukin-2 secretion J:240602
increased NK T cell number J:240602
increased single-positive T cell number J:240602
increased splenocyte number J:240602
increased T cell proliferation J:240602
Setd1atm1a(EUCOMM)Wtsi/Setd1a+
(C57BL/6N-Setd1atm1a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:175295
Setd2tm1c(NCOM)Mfgc/Setd2tm1c(NCOM)Mfgc
Tg(Lck-cre)#Zhu/0

(involves: C57BL/6 * SJL/J)
increased gamma-delta T cell number J:243973
Setd3tm1.1(NCOM)Mfgc/Setd3tm1.1(NCOM)Mfgc
(C57BL/6N-Setd3tm1.1(NCOM)Mfgc/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Setd3tm1.1(NCOM)Mfgc/Setd3tm1.1(NCOM)Mfgc
(involves: C57BL/6NCrl)
decreased susceptibility to Riboviria infection J:293475
Setd5tm1a(EUCOMM)Wtsi/Setd5+
(C57BL/6N-Setd5tm1a(EUCOMM)Wtsi/Wtsi)
abnormal thymus morphology J:239583
blood in lymph vessels J:239583
enlarged lymphatic vessel J:239583
increased monocyte cell number J:211773
increased regulatory T cell number J:211773
small thymus J:239583
Setd7tm1Frga/Setd7+
(involves: 129 * C57BL/6)
abnormal spleen physiology J:136558
Setd7tm1Frga/Setd7tm1Frga
(involves: 129 * C57BL/6)
abnormal spleen physiology J:136558
Setdb2tm1Desr/Setdb2tm1Desr
(B6.Cg-Setdb2tm1Desr)
abnormal response to infection J:222611
increased neutrophil cell number J:222611
increased susceptibility to bacterial infection J:222611
Setxtm1b(EUCOMM)Wtsi/Setxtm1b(EUCOMM)Wtsi
(C57BL/6N-Setxtm1b(EUCOMM)Wtsi/Ics)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased NK cell number J:211773
sevr/sevr
(C3H/HeJ-sevr/GrsrJ)
thymus atrophy J:109437
Sf3b1tm1.1Mdf/Sf3b1+
Tet2tm1.1Iaai/Tet2tm1.1Iaai
Tg(Mx1-cre)1Cgn/?

(involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA/J)
abnormal myelopoiesis J:234976
decreased B cell number J:234976
enlarged spleen J:234976
increased granulocyte number J:234976
Sf3b1tm1.1Mdf/Sf3b1+
Tg(Mx1-cre)1Cgn/?

(involves: 129S4/SvJae * C57BL/6 * CBA/J)
abnormal myelopoiesis J:234976
Sf3b1tm1Hko/Sf3b1+
(Not Specified)
increased spleen red pulp amount J:324276
Sfmbt2em1(IMPC)Mbp/Sfmbt2+
(C57BL/6NCrl-Sfmbt2em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Sfntm1Mak/Sfntm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:168328
abnormal spleen B cell follicle morphology J:168328
abnormal spleen morphology J:168328
absent spleen marginal zone J:168328
decreased B cell number J:168328
decreased B-1a cell number J:168328
decreased follicular B cell number J:168328
decreased IgG level J:168328
decreased IgM level J:168328
decreased marginal zone B cell number J:168328
immune system phenotype J:168328
increased B cell apoptosis J:168328
increased B cell proliferation J:168328
increased susceptibility to Riboviria infection J:168328
increased susceptibility to Riboviria infection induced morbidity/mortality J:168328
Sfrp1tm1Bsk/Sfrp1tm1Bsk
(involves: 129S5/SvEvBrd * C57BL/6)
decreased leukocyte cell number J:89547
decreased lymphocyte cell number J:89547
decreased neutrophil cell number J:89547
Sfrp4tm1.1Blan/Sfrp4tm1.1Blan
(Not Specified)
increased osteoclast cell number J:234467
Sfrp4tm1.1Lex/Sfrp4tm1.1Lex
(Not Specified)
increased osteoclast cell number J:234467
Sftpa1tm1Haw/Sftpa1tm1Haw
(involves: 129/Sv * C57BL/6 * CD-1)
abnormal cytokine level J:86024
abnormal inflammatory response J:85432
abnormal interferon level J:86024
abnormal interleukin level J:86024
increased susceptibility to Orthomyxoviridae infection J:86024
Sftpa1tm1Kor/Sftpa1tm1Kor
(involves: 129P2/OlaHsd * NIH Black Swiss)
immune system phenotype J:35250
increased susceptibility to bacterial infection J:120552, J:110382
lung inflammation J:110382
Sftpa1tm1Kor/Sftpa1tm1Kor
(involves: 129P2/OlaHsd)
immune system phenotype J:130958
lung inflammation J:107841
Sftpa1tm1Kor/Sftpa1tm1Kor
(involves: 129P2/OlaHsd * Black Swiss * C3H/HeN)
increased susceptibility to bacterial infection J:130297
Sftpa1tm2Haw/Sftpa1tm2Haw
Sftpdtm2Haw/Sftpdtm2Haw

(involves: C57BL/6J * CD-1)
abnormal alveolar macrophage morphology J:86022
increased monocyte cell number J:86022
Sftpctm1Swg/Sftpctm1Swg
(either: 129 or (involves: 129 * Black Swiss))
conjunctivitis J:82925
Sftpdtm1Haw/Sftpdtm1Haw
(involves: C57BL/6J * CD-1)
abnormal alveolar macrophage morphology J:98220, J:50147
abnormal macrophage physiology J:98220
Sftpdtm1Jhf/Sftpdtm1Jhf
(involves: 129P2/OlaHsd * Black Swiss)
abnormal alveolar macrophage morphology J:50436
abnormal chemokine level J:72681
abnormal cytokine level J:72681, J:62282
abnormal macrophage morphology J:62282, J:50436
abnormal macrophage physiology J:62282
abnormal neutrophil physiology J:72681
increased macrophage cell number J:62282, J:50436
increased neutrophil cell number J:72681
increased susceptibility to Orthomyxoviridae infection J:72681
lung inflammation J:62282, J:50436
Sfxn4tm1b(KOMP)Wtsi/Sfxn4tm1b(KOMP)Wtsi
(C57BL/6N-Sfxn4tm1b(KOMP)Wtsi/J)
decreased leukocyte cell number J:211773
Sgcatm1Kcam/Sgcatm1Kcam
(involves: 129S1/Sv * 129X1/SvJ)
heart inflammation J:177563
Sgcatm1Kcam/Sgcatm1Kcam
Sgcetm1Vinni/Sgcetm1Vinni

(involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J)
heart inflammation J:177563
Sgcbtm1Oza/Sgcbtm1Oza
(involves: 129S4/SvJae * C57BL/6J)
myositis J:57590
Sgk3fz-ica/Sgk3fz-ica
(Swiss albino)
abnormal inflammatory response J:107373
sgl/sgl
(involves: C3H * C57BL/6J)
abnormal lymph node morphology J:56826
conjunctivitis J:56826
Sgms1tm1Jia/Sgms1tm1Jia
(involves: C57BL/6)
abnormal cytokine level J:201497
abnormal cytokine secretion J:201497
decreased circulating interleukin-6 level J:201497
decreased circulating tumor necrosis factor level J:201497
decreased interleukin-6 secretion J:201497
decreased tumor necrosis factor secretion J:201497
Sgms2tm1Jia/Sgms2tm1Jia
(involves: 129 * C57BL/6)
abnormal macrophage morphology J:162226
abnormal macrophage physiology J:162192, J:162226
Sgp5NZB/?
(involves: C57BL/6 * NZB * SB/Le)
abnormal immune serum protein physiology J:95829
glomerulonephritis J:95829
increased susceptibility to type III hypersensitivity reaction J:95829
Sgp5NZB/Sgp5NZB
(C57BL/6-Nba2 Yaa)
abnormal immune serum protein physiology J:95829
Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal lymph node morphology J:145159
abnormal lymphopoiesis J:145159
abnormal osteoclast morphology J:145159
abnormal spleen periarteriolar lymphoid sheath morphology J:145159
decreased B cell number J:145159
decreased double-positive T cell number J:145159
decreased lymphocyte cell number J:145159
decreased neutrophil cell number J:145159
decreased pre-B cell number J:145159
decreased T cell number J:145159
increased CD4-positive, alpha-beta T cell number J:145159
increased CD8-positive, alpha-beta T cell number J:145159
increased granulocyte number J:145159
increased monocyte cell number J:145159
increased osteoclast cell number J:145159
lymph node hypoplasia J:145159
lymphoid hypoplasia J:145159
spleen hypoplasia J:145159
thymus cortex hypoplasia J:145159
thymus hypoplasia J:145159
thymus medulla hyperplasia J:145159
Sgpl1Gt(OST58278)Lex/Sgpl1tm1(SGPL1)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal immune system organ morphology J:145159
abnormal osteoclast morphology J:145159
decreased T cell number J:145159
thymus cortex hypoplasia J:145159
thymus medulla hyperplasia J:145159
Sgpl1Gt(ROSA)78Sor/Sgpl1Gt(ROSA)78Sor
(involves: 129S4/SvJaeSor)
kidney inflammation J:117491
Sgpl1Gt(ROSA)78Sor/Sgpl1Gt(ROSA)78Sor
(involves: 129S4/SvJaeSor * C57BL/6)
abnormal immune system physiology J:187619
abnormal leukocyte migration J:187619
abnormal T cell physiology J:187619
decreased lymphocyte cell number J:187619
Sgpl1tm1(SGPL1)Lex/Sgpl1tm1(SGPL1)Lex
(involves: 129S4/SvJae * 129S5/SvEvBrd * C57BL/6J)
abnormal immune system organ morphology J:145159
abnormal lymph node morphology J:145159
abnormal thymus lobule morphology J:145159
decreased B cell number J:145159
decreased CD4-positive, alpha-beta T cell number J:145159
decreased CD8-positive, alpha-beta T cell number J:145159
decreased lymphocyte cell number J:145159
decreased T cell number J:145159
increased single-positive T cell number J:145159
Sgpl1tm1.2Npa/Sgpl1tm1.2Npa
(involves: BALB/cJ * C57BL/6)
spleen hypoplasia J:199525
Sgshmps3a/Sgshmps3a
(involves: 129X1/SvJ * CD-1 * C57BL/6 * SJL)
enlarged spleen J:72142
Sgsm1tm1b(EUCOMM)Wtsi/Sgsm1tm1b(EUCOMM)Wtsi
(C57BL/6N-Sgsm1tm1b(EUCOMM)Wtsi/Wtsi)
decreased CD4-positive, alpha-beta T cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
Sh2b1tm1Ayos/Sh2b1tm1Ayos
(involves: C57BL/6)
immune system phenotype J:78931
Sh2b2tm1Yeb/Sh2b2tm1Yeb
(involves: C57BL/6)
abnormal B cell differentiation J:88527
increased B-1 B cell number J:88527
increased IgG3 level J:88527
Sh2b3tm1Paw/Sh2b3tm1Paw
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
abnormal granulocyte differentiation J:77248
abnormal leukocyte cell number J:77248
abnormal monocyte differentiation J:77248
enlarged lymph nodes J:77248
enlarged spleen J:77248
increased B cell number J:77248
spleen fibrosis J:77248
Sh2b3tm1Paw/Sh2b3tm1Paw
(B6.129-Sh2b3tm1Paw)
spleen hyperplasia J:107464
Sh2b3tm1Paw/Sh2b3tm1Paw
(involves: 129S1/Sv * 129X1/SvJ)
decreased B cell number J:161643
enlarged spleen J:161643
increased granulocyte number J:161643
increased leukocyte cell number J:161643
increased lymphocyte cell number J:161643
increased monocyte cell number J:161643
increased neutrophil cell number J:161643
myeloid hyperplasia J:161643
Sh2d1atm1.1Knic/Y
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129S/SvEv * 129X1/SvJ * C57BL/6)
abnormal NK T cell physiology J:196692
decreased circulating interleukin-4 level J:196692
decreased interferon-gamma secretion J:196692
immune system phenotype J:196692
Sh2d1atm1.1Knic/Sh2d1atm1.1Knic
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Ndor1Tg(UBC-cre/ERT2)1Ejb/0

(involves: 129S/SvEv * 129X1/SvJ * C57BL/6)
abnormal NK T cell physiology J:196692
decreased circulating interleukin-4 level J:196692
decreased interferon-gamma secretion J:196692
immune system phenotype J:196692
Sh2d1atm1Cpt/Y
(involves: 129S4/SvJae * C57BL/6)
abnormal cytokine secretion J:97756
abnormal germinal center B cell physiology J:189126
abnormal humoral immune response J:189126
abnormal immunoglobulin level J:189126
abnormal NK T cell physiology J:189126
decreased NK T cell number J:189126
increased susceptibility to Riboviria infection J:97756
increased T cell proliferation J:97756
Sh2d1atm1Cpt/Y
(involves: 129S4/SvJae * BALB/c)
abnormal cytokine secretion J:97756
abnormal germinal center B cell morphology J:189126
decreased germinal center B cell number J:189126
decreased IgE level J:97756
decreased IgG level J:189126
decreased NK T cell number J:189126
decreased susceptibility to parasitic infection J:97756
immune system phenotype J:189126
Sh2d1atm1Cpt/Y
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c)
decreased germinal center B cell number J:189126
decreased IgG level J:189126
Sh2d1atm1Cpt/Sh2d1a+
(involves: 129S4/SvJae * C57BL/6)
abnormal cytokine secretion J:97756
increased T cell proliferation J:97756
Sh2d1atm1Cpt/Sh2d1atm1Cpt
(B6.129S4-Sh2d1atm1Cpt)
abnormal humoral immune response J:97388
absent NK T cells J:97690
decreased IgG1 level J:97388
decreased IgM level J:97388
decreased NK T cell number J:97690
decreased transitional stage B cell number J:97690
increased B cell number J:97388
increased IgG2a level J:97388
Sh2d1atm1Cpt/Sh2d1atm1Cpt
(C.129S4-Sh2d1atm1Cpt)
decreased IgG level J:97388
decreased IgM level J:97388
decreased spleen germinal center number J:97388
Sh2d1atm1Cpt/Sh2d1atm1Cpt
(involves: 129S4/SvJae * C57BL/6)
abnormal cytokine secretion J:97756
abnormal germinal center B cell physiology J:189126
abnormal humoral immune response J:189126
abnormal immunoglobulin level J:189126
abnormal NK T cell physiology J:189126
decreased NK T cell number J:189126
increased susceptibility to Riboviria infection J:97756
increased T cell proliferation J:97756
Sh2d1atm1Cpt/Sh2d1atm1Cpt
(involves: 129S4/SvJae * BALB/c)
abnormal cytokine secretion J:97756
abnormal germinal center B cell morphology J:189126
decreased germinal center B cell number J:189126
decreased IgE level J:97756
decreased IgG level J:189126
decreased NK T cell number J:189126
decreased susceptibility to parasitic infection J:97756
immune system phenotype J:189126
Sh2d1atm1Cpt/Sh2d1atm1Cpt
(involves: 129S4/SvJae)
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1atm1Cpt/Sh2d1atm1Cpt
Sh2d1b1/Sh2d1b2tm1.1Cpt/Sh2d1b1/Sh2d1b2tm1.1Cpt

(involves: 129S4/SvJae * BALB/cJ)
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1atm1Cpt/Sh2d1atm1Cpt
Sh2d1b1/Sh2d1b2tm1.1Cpt/Sh2d1b1/Sh2d1b2tm1.1Cpt

(involves: 129S4/SvJae * BALB/cJ)
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1atm1Cpt/Sh2d1atm1Cpt
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c)
decreased germinal center B cell number J:189126
decreased IgG level J:189126
Sh2d1atm1Lyin/Y
(involves: 129S2/SvPas * C57BL/6)
abnormal immune system physiology J:97346
chronic inflammation J:97346
decreased IgE level J:97346
decreased IgG level J:97346
decreased immunoglobulin level J:97346
increased CD8-positive, alpha-beta T cell number J:97346
Sh2d1atm1Lyin/Sh2d1atm1Lyin
(involves: 129S2/SvPas * C57BL/6)
abnormal immune system physiology J:97346
chronic inflammation J:97346
decreased IgE level J:97346
decreased IgG level J:97346
decreased immunoglobulin level J:97346
increased CD8-positive, alpha-beta T cell number J:97346
Sh2d1atm1Lyin/Sh2d1atm1Lyin
(involves: 129S1/Sv * 129X1/SvJ)
impaired natural killer cell mediated cytotoxicity J:110195
Sh2d1atm1Pls/Y
(involves: 129S6/SvEvTac)
abnormal CD4-positive, alpha-beta T cell physiology J:157915
abnormal cytotoxic T cell physiology J:187431
abnormal long lived plasma cell morphology J:157915
abnormal NK T cell morphology J:196692
decreased CD4-positive, alpha-beta T cell number J:157915
decreased IgG level J:157915
decreased interleukin-21 secretion J:157915
Sh2d1atm1Pls/Sh2d1atm1Pls
(either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * C57BL/6))
abnormal lymphocyte cell number J:70032
abnormal T-helper 1 cell morphology J:70032
abnormal T-helper 2 cell morphology J:70032
decreased IgE level J:70032
increased susceptibility to infection J:70032
increased susceptibility to parasitic infection J:70032
increased susceptibility to Riboviria infection J:70032
increased T cell proliferation J:70032
Sh2d1atm1Pls/Sh2d1atm1Pls
(involves: BALB/c)
decreased susceptibility to parasitic infection J:90484
Sh2d1atm1Pls/Sh2d1atm1Pls
(involves: 129S6/SvEvTac * C57BL/6)
immune system phenotype J:92740
Sh2d1atm1Pls/Sh2d1atm1Pls
(B6.129S6-Sh2d1atm1Pls)
abnormal CD4-positive, alpha-beta T cell physiology J:93886
abnormal NK cell physiology J:187430
decreased IgE level J:93886
decreased interferon-gamma secretion J:187430
Sh2d1atm1Pls/Sh2d1atm1Pls
(involves: 129S6/SvEvTac)
abnormal CD4-positive, alpha-beta T cell physiology J:157915
abnormal cytotoxic T cell physiology J:187431
abnormal long lived plasma cell morphology J:157915
abnormal NK T cell morphology J:196692
decreased CD4-positive, alpha-beta T cell number J:157915
decreased IgG level J:157915
decreased interleukin-21 secretion J:157915
Sh2d1atm1Pls/Sh2d1atm1Pls
Sh2d1b1tm3Vei/Sh2d1b1tm3Vei

(involves: 129S6/SvEvTac * C57BL/6)
abnormal NK cell physiology J:187430
Sh2d1atm1Pls/Sh2d1atm1Pls
Slamf6tm1Lex/Slamf6tm1Lex

(B6.129S-Slamf6tm1Lex Sh2d1atm1Pls)
immune system phenotype J:187429
Sh2d1atm1Pls/Sh2d1atm1Pls
Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J)
immune system phenotype J:187431
Sh2d1atm1Pls/Sh2d1atm1Pls
Tg(DO11.10)10Dlo/Tg(DO11.10)10Dlo

(involves: BALB/c * C3H * C57BL/6)
abnormal cytokine secretion J:90484
Sh2d1atm1Pls/Sh2d1atm1Pls
Tg(TcraTcrb)425Cbn/?

(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:157915
Sh2d1atm1Pls/Sh2d1atm1Pls
Tg(TcraTcrb)1100Mjb/0

(involves: 129S6/SvEvTac * C57BL/6)
abnormal cytotoxic T cell physiology J:187431
decreased cytotoxic T cell cytolysis J:187431
decreased interferon-gamma secretion J:187431
Sh2d1atm1Vei/Sh2d1atm1Vei
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:93886
abnormal memory T cell physiology J:93886
decreased IgE level J:93886
Sh2d1atm1Vei/Sh2d1atm1Vei
(B6.129-Sh2d1atm1Vei)
abnormal NK cell physiology J:187430
decreased interferon-gamma secretion J:187430
Sh2d1atm1Vei/Sh2d1atm1Vei
Sh2d1b1tm3Vei/Sh2d1b1tm3Vei

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal NK cell physiology J:187430
Sh2d1atm2.1Cpt/Y
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NTac)
abnormal germinal center B cell physiology J:189126
abnormal humoral immune response J:189126
decreased IgG level J:189126
decreased IgM level J:189126
immune system phenotype J:189126
Sh2d1atm2.1Cpt/Sh2d1atm2.1Cpt
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NTac)
abnormal germinal center B cell physiology J:189126
abnormal humoral immune response J:189126
decreased IgG level J:189126
decreased IgM level J:189126
immune system phenotype J:189126
Sh2d1atm2.1Vei/Sh2d1atm2.1Vei
(involves: C57BL/6)
decreased germinal center B cell number J:131618
decreased IgE level J:131618
decreased IgG1 level J:131618
decreased IgG2a level J:131618
decreased IgG2b level J:131618
decreased IgG3 level J:131618
decreased IgM level J:131618
decreased NK T cell number J:131618
Sh2d1atm2Vei/Sh2d1atm2Vei
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:131618
Sh2d1atm2Vei/Sh2d1atm2Vei
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
decreased germinal center B cell number J:131618
decreased IgE level J:131618
decreased IgG1 level J:131618
decreased IgG2a level J:131618
decreased IgG2b level J:131618
decreased IgG3 level J:131618
decreased IgM level J:131618
decreased NK T cell number J:131618
Sh2d1atm2Vei/Sh2d1atm2Vei
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6)
decreased germinal center B cell number J:131618
decreased IgE level J:131618
decreased IgG1 level J:131618
decreased IgG2a level J:131618
decreased IgG2b level J:131618
decreased IgG3 level J:131618
decreased IgM level J:131618
decreased NK T cell number J:131618
Sh2d1b1/Sh2d1b2tm1.1Cpt/Sh2d1b1/Sh2d1b2tm1.1Cpt
(involves: BALB/cJ)
decreased interferon-gamma secretion J:166054
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1b1/Sh2d1b2tm1.1Cpt/Sh2d1b1/Sh2d1b2tm1.1Cpt
(involves: BALB/cJ)
decreased interferon-gamma secretion J:166054
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1b1tm1.1Cpt/Sh2d1b1tm1.1Cpt
(involves: BALB/cJ * C57BL/6)
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1b1tm1Vei/Sh2d1b1tm1Vei
(involves: 129S1/Sv * 129X1/SvJ)
increased interferon-gamma secretion J:110195
increased natural killer cell mediated cytotoxicity J:110195
Sh2d1b1tm2Vei/Sh2d1b1tm2Vei
Sh2d1b2tm1Vei/Sh2d1b2tm1Vei

(involves: 129S1/Sv * 129X1/SvJ)
impaired natural killer cell mediated cytotoxicity J:145969
Sh2d1b1tm3Vei/Sh2d1b1tm3Vei
(involves: C57BL/6)
abnormal NK cell physiology J:187430
Sh2d1b2tm1.1Cpt/Sh2d1b2tm1.1Cpt
(involves: BALB/cJ * C57BL/6)
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1b2tm1Vei/Sh2d1b2tm1Vei
(involves: 129S1/Sv * 129X1/SvJ)
impaired natural killer cell mediated cytotoxicity J:145969
increased natural killer cell mediated cytotoxicity J:110195
Sh2d2atm1Jbs/Sh2d2atm1Jbs
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased interferon-gamma secretion J:64938
decreased interleukin-2 secretion J:64938
decreased T cell proliferation J:64938
immune system phenotype J:64938
increased interleukin-4 secretion J:64938
Sh2d3ctm1Lex/Sh2d3ctm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal B cell physiology J:161448
abnormal humoral immune response J:161448
abnormal leukocyte migration J:161448
abnormal marginal zone B cell physiology J:161448
decreased IgG1 level J:161448
decreased IgG2b level J:161448
decreased IgG3 level J:161448
decreased IgM level J:161448
decreased interleukin-6 secretion J:161448
decreased marginal zone B cell number J:161448
Sh3bp2tm1.1Ics/Sh3bp2+
(involves: 129S2/SvPas * C57BL/6)
abnormal circulating cytokine level J:221901
abnormal macrophage physiology J:221901
increased susceptibility to bacterial infection J:221901
increased tumor necrosis factor secretion J:221901
Sh3bp2tm1.1Ics/Sh3bp2tm1.1Ics
(involves: 129S2/SvPas * C57BL/6)
abnormal circulating cytokine level J:221901
enlarged lymph nodes J:221901
increased circulating interleukin-6 level J:221901
increased circulating interleukin-12 level J:221901
increased circulating tumor necrosis factor level J:221901
increased inflammatory response J:221901
increased monocyte cell number J:221901
increased tumor necrosis factor secretion J:221901
Sh3bp2tm1Bjro/Sh3bp2+
(involves: 129S4/SvJae * BALB/cJ * C57BL/6J)
abnormal osteoclast differentiation J:117880
abnormal osteoclast physiology J:117880
immune system phenotype J:117880
increased osteoclast cell number J:117880
Sh3bp2tm1Bjro/Sh3bp2tm1Bjro
(involves: 129S4/SvJae * BALB/cJ * C57BL/6J)
abnormal B cell number J:117880
abnormal immune system organ morphology J:117880
abnormal macrophage physiology J:117880
abnormal osteoclast differentiation J:117880
abnormal osteoclast physiology J:117880
blepharitis J:117880
dermatitis J:117880
enlarged lymph nodes J:117880
increased circulating tumor necrosis factor level J:117880
increased inflammatory response J:117880
increased osteoclast cell number J:117880
increased spleen red pulp amount J:117880
joint inflammation J:117880
liver inflammation J:117880
lung inflammation J:117880
myositis J:117880
osteomyelitis J:117880
spinal cord inflammation J:117880
stomach inflammation J:117880
Sh3bp2tm1Bjro/Sh3bp2tm1Bjro
Tnftm1Gkl/Tnftm1Gkl

(involves: 129S/SvEv * 129S4/SvJae * BALB/cJ * C57BL/6J)
abnormal osteoclast differentiation J:117880
immune system phenotype J:117880
Sh3bp2tm1Geha/Sh3bp2tm1Geha
(Not Specified)
abnormal B cell number J:110319
abnormal B cell physiology J:110319
decreased B cell proliferation J:110319
immune system phenotype J:110319
increased pre-B cell number J:110319
Sh3bp2tm1Rtpl/Sh3bp2tm1Rtpl
(B6.129P2-Sh3bp2tm1Rtpl)
abnormal B cell number J:121380
abnormal marginal zone B cell physiology J:121380
abnormal spleen marginal zone morphology J:121380
decreased B cell proliferation J:121380
decreased B-1 B cell number J:121380
decreased IgA level J:121380
decreased IgG1 level J:121380
decreased IgG3 level J:121380
decreased IgM level J:121380
decreased immunoglobulin level J:121380
decreased pro-B cell number J:121380
decreased transitional stage B cell number J:121380
increased B cell apoptosis J:121380
increased marginal zone B cell number J:121380
Sh3bp2tm1Rtpl/Sh3bp2tm1Rtpl
(involves: 129P2/OlaHsd * C57BL/6)
abnormal circulating cytokine level J:221901
abnormal interleukin-6 secretion J:221901
abnormal macrophage physiology J:221901
decreased tumor necrosis factor secretion J:221901
impaired macrophage phagocytosis J:221901
Sh3glb2Gt(OST224737)Lex/Sh3glb2Gt(OST224737)Lex
(B6.129S5-Sh3glb2Gt(OST224737)Lex)
abnormal response to infection J:246421
Sh3kbp1tm1Kuro/Sh3kbp1tm1Kuro
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6 * NZB)
abnormal B cell physiology J:176805
abnormal humoral immune response J:176805
abnormal lymphocyte cell number J:176805
decreased B cell number J:176805
decreased B-1a cell number J:176805
decreased follicular B cell number J:176805
decreased immature B cell number J:176805
decreased transitional stage T2 B cell number J:176805
decreased transitional stage T3 B cell number J:176805
immune system phenotype J:176805
Sh3kbp1tm1Kuro/Sh3kbp1tm1Kuro
Cd79atm1(cre)Reth/Cd79a+
Gt(ROSA)26Sortm4(Ikbkb)Rsky/?

(involves: BALB/c * C57BL/6 * NZB)
decreased B-1a cell number J:176805
immune system phenotype J:176805
Sh3pxd2atm1b(EUCOMM)Wtsi/Sh3pxd2atm1b(EUCOMM)Wtsi
(C57BL/6N-Sh3pxd2atm1b(EUCOMM)Wtsi/Wtsi)
abnormal lymphatic vessel morphology J:239583
abnormal thymus topology J:239583
absent connection between subcutaneous lymph vessels and lymph sac J:239583
blood in lymph vessels J:239583
Sh3pxd2bnee/Sh3pxd2bnee
(B10.Cg-H2h4 Sh3pxd2bnee/GrsrJ)
eye inflammation J:262132
hypopyon J:262132
increased susceptibility to otitis media J:153369
Sh3tc1tm1b(EUCOMM)Hmgu/Sh3tc1tm1b(EUCOMM)Hmgu
(C57BL/6N-Sh3tc1tm1b(EUCOMM)Hmgu/Orl)
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Sh3yl1tm1Syb/Sh3yl1tm1Syb
(involves: C57BL/6N)
decreased interleukin-1 beta secretion J:298830
decreased susceptibility to endotoxin shock J:298830
decreased tumor necrosis factor secretion J:298830
Shank2em2(IMPC)Rbrc/Shank2em2(IMPC)Rbrc
(C57BL/6NJcl-Shank2em2(IMPC)Rbrc/Rbrc)
abnormal neutrophil cell number J:211773
Sharpincpdm-Dem/Sharpincpdm-Dem
(CBy.OcB3-Sharpincpdm-Dem)
abnormal immune system organ morphology J:121810
dermatitis J:121810
skin inflammation J:121810
Sharpincpdm/Sharpincpdm
(C57BL/KaLawRij-Sharpincpdm)
abnormal humoral immune response J:53575
abnormal immune system organ morphology J:14539
abnormal lymph node morphology J:14539
abnormal mesenteric lymph node morphology J:53575
abnormal peripheral lymph node morphology J:53575
abnormal spleen morphology J:53575
abnormal spleen white pulp morphology J:31745, J:53575
absent Peyer's patches J:53575
absent spleen B cell follicles J:53575
absent spleen germinal center J:53575
absent spleen marginal zone J:53575
cutaneous mastocytosis J:31745, J:14539
decreased B cell number J:53575
decreased CD4-positive, alpha-beta T cell number J:53575
decreased IgA level J:53575
decreased IgE level J:31745, J:53575
decreased IgG level J:53575
decreased immunoglobulin level J:53575
decreased T cell number J:53575
dermatitis J:14539
enlarged spleen J:14539, J:53575
esophageal inflammation J:31745
folliculitis J:31745
increased eosinophil cell number J:31745, J:14539
increased IgM level J:53575
joint inflammation J:14539
large lymphoid organs J:31745
lung inflammation J:31745
lymph node inflammation J:31745
stomach inflammation J:31745
Sharpincpdm/Sharpincpdm
(involves: C57BL/KaLawRij * FVB/NJ)
absent Peyer's patches J:121810
absent spleen B cell follicles J:121810
absent spleen germinal center J:121810
skin inflammation J:121810
Shc1tm1Ravi/Shc1tm1Ravi
Tg(Lck-cre)1Cwi/?

(involves: 129 * C57BL/6)
abnormal double-negative T cell morphology J:78180
decreased double-positive T cell number J:78180
decreased single-positive T cell number J:78180
thymus hypoplasia J:78180
Shcbp1tm1c(EUCOMM)Wtsi/Shcbp1tm1c(EUCOMM)Wtsi
Tg(Lck-cre)1Cwi/?

(involves: C57BL/6 * DBA/2)
decreased susceptibility to experimental autoimmune encephalomyelitis J:212898
immune system phenotype J:212898
Shcbp1tm1d(EUCOMM)Wtsi/Shcbp1tm1d(EUCOMM)Wtsi
(involves: C57BL/6N * FVB/N)
decreased B cell number J:212898
decreased CD4-positive, alpha-beta T cell number J:212898
decreased macrophage cell number J:212898
decreased susceptibility to experimental autoimmune encephalomyelitis J:212898
decreased T cell number J:212898
immune system phenotype J:212898
Shisa6em1(IMPC)Tcp/Shisa6em1(IMPC)Tcp
(C57BL/6N-Shisa6em1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Shisal1em1(IMPC)Ccpcz/Shisal1em1(IMPC)Ccpcz
(C57BL/6N-Shisal1em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Shld1em1(IMPC)Mbp/Shld1em1(IMPC)Mbp
(C57BL/6NCrl-Shld1em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Shld1em1Nus/Shld1em1Nus
(involves: C57BL/6NCrl)
abnormal class switch recombination J:307190
Shmt2em1(IMPC)Bay/Shmt2+
(C57BL/6N-Shmt2em1(IMPC)Bay/Bay)
increased spleen weight J:211773
sho/sho
(Not Specified)
small thymus J:255
Shprhem1(IMPC)Tcp/Shprhem1(IMPC)Tcp
(C57BL/6NCrl-Shprhem1(IMPC)Tcp/Tcp)
enlarged thymus J:211773
Siaetm1.2Avrk/Siaetm1.2Avrk
(B6J.129(Cg)-Siaetm1.2Avrk)
immune system phenotype J:231437
Siaetm1a(EUCOMM)Wtsi/Siaetm1a(EUCOMM)Wtsi
(involves: C57BL/6N * C57BL/6NTac)
immune system phenotype J:231437
SialsMRL/MpJ/SialsMRL/MpJ
(involves: C3H/HeJ * MRL/MpJ)
salivary gland inflammation J:66636
Sidt1tm1.1(KOMP)Vlcg/Sidt1tm1.1(KOMP)Vlcg
(C57BL/6N-Sidt1tm1.1(KOMP)Vlcg/Ucd)
abnormal lymph node morphology J:211773
Sidt2tm1.1Hzha/Sidt2tm1.1Hzha
(involves: 129S6/SvEvTac * C57BL/6J)
liver inflammation J:236042
Sigirrtm1Lix/Sigirrtm1Lix
(involves: 129S6/SvEvTac * BALB/c)
abnormal chemokine secretion J:85151
abnormal splenocyte proliferation J:85151
increased inflammatory response J:85151
increased susceptibility to endotoxin shock J:85151
Sigirrtm1Mant/Sigirrtm1Mant
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal chemokine secretion J:88907
abnormal dendritic cell physiology J:88907
abnormal interleukin secretion J:88907
immune system phenotype J:88907
increased interleukin-6 secretion J:88907
increased susceptibility to induced colitis J:88907
Siglec1tm1(HBEGF)Mtka/Siglec1tm1(HBEGF)Mtka
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/?

(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
abnormal dendritic cell physiology J:123958
abnormal immune system physiology J:123958
abnormal immune tolerance J:123958
abnormal macrophage physiology J:123958
abnormal metallophilic macrophage morphology J:123958
abnormal spleen marginal zone macrophage morphology J:123958
Siglec1tm1Croc/Siglec1tm1Croc
(B6.129-Siglec1tm1Croc)
abnormal B cell number J:105546
abnormal T cell subpopulation ratio J:105546
decreased circulating interleukin-6 level J:189854
decreased circulating tumor necrosis factor level J:189854
decreased follicular B cell number J:105546
decreased IgM level J:105546
decreased interleukin-6 secretion J:189854
decreased interleukin-10 secretion J:189854
decreased interleukin-12 secretion J:189854
decreased tumor necrosis factor secretion J:189854
impaired macrophage phagocytosis J:189854
increased CD8-positive, alpha-beta T cell number J:105546
increased marginal zone B cell number J:105546
increased susceptibility to bacterial infection J:189854
Siglec1tm2.1Croc/Siglec1tm2.1Croc
(B6.129P2(C)-Siglec1tm2.1Croc)
decreased circulating interleukin-6 level J:189854
decreased circulating tumor necrosis factor level J:189854
decreased susceptibility to bacterial infection J:189854
impaired macrophage phagocytosis J:189854
Siglec15tm1Yohi/Siglec15tm1Yohi
(B6.129S6-Siglec15tm1Yohi)
abnormal osteoclast differentiation J:193852
Siglecetm1.1(SIGLEC16)Avrk/Siglecetm1.1(SIGLEC16)Avrk
(involves: C57BL/6)
abnormal cytokine level J:264224
decreased susceptibility to bacterial infection J:264224
increased circulating interleukin-6 level J:264224
increased circulating interleukin-12 level J:264224
Siglecetm1Arte/Siglecetm1Arte
(involves: C57BL/6)
abnormal macrophage physiology J:195429
abnormal neutrophil physiology J:195429
Siglecetm1Croc/Siglecetm1Croc
(B6.129P2-Siglecetm1Croc)
abnormal macrophage physiology J:195429
abnormal neutrophil physiology J:195429
Siglecftm1.2Avrk/Siglecftm1.2Avrk
(B6.129(FVB)-Siglecftm1.2Avrk)
abnormal eosinophil differentiation J:204811
abnormal eosinophil physiology J:204811
immune system phenotype J:204811
increased eosinophil cell number J:204811
lung inflammation J:204811
SiglecgM1Btlr/SiglecgM1Btlr
(C57BL/6J-SiglecgM1Btlr)
increased B-1 B cell number J:265179
Siglecgm2Btlr/Siglecgm2Btlr
(C57BL/6J-Siglecgm2Btlr)
decreased CD8-positive, alpha-beta memory T cell number J:265183
increased B-1 B cell number J:265183
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:265183
SiglecgM3Btlr/SiglecgM3Btlr
(C57BL/6J-SiglecgM3Btlr)
decreased B-2 B cell number J:265185
decreased IgM level J:265185
increased B-1 B cell number J:265185
increased B-1a cell number J:265185
SiglecgM4Btlr/SiglecgM4Btlr
(C57BL/6J-SiglecgM4Btlr)
increased B-1 B cell number J:272021
SiglecgM5Btlr/SiglecgM5Btlr
(C57BL/6J-SiglecgM5Btlr)
increased B-1a cell number J:272022
Siglecgtm1Lnit/Siglecgtm1Lnit
(involves: BALB/c)
abnormal plasma cell differentiation J:123353
autoimmune response J:123353
decreased IgG2a level J:123353
increased B-1 B cell number J:123353
increased B-1a cell number J:123353
increased B-1b cell number J:123353
increased IgM level J:123353
Siglecgtm1Yliu/Siglecgtm1Yliu
(C57BL/6-Siglecgtm1Yliu)
increased B-1a cell number J:130017
increased IgM level J:130017
increased pre-B cell number J:130017
Siglechtm1.1Cfg/Siglechtm1.1Cfg
(involves: C57BL/6)
immune system phenotype J:214874
increased T cell proliferation J:217719
Siglechtm1.1Cln/Siglech+
Tg(CLEC4C-HBEGF)956Cln/0

(involves: C57BL/6)
decreased plasmacytoid dendritic cell number J:166504
Siglechtm1.1Ksat/Siglechtm1.1Ksat
(B6.Cg-Siglechtm1.1Ksat)
abnormal circulating cytokine level J:179283
abnormal dendritic cell antigen presentation J:179283
abnormal plasmacytoid dendritic cell physiology J:179283
abnormal regulatory T cell morphology J:179283
decreased circulating interferon-alpha level J:179283
decreased circulating interleukin-12b level J:179283
decreased plasmacytoid dendritic cell number J:179283
decreased susceptibility to bacterial infection induced morbidity/mortality J:179283
decreased susceptibility to infection induced morbidity/mortality J:179283
decreased T-helper 17 cell number J:179283
increased circulating interferon-alpha level J:179283
increased circulating interleukin-12b level J:179283
increased T-helper 17 cell number J:179283
Sik2tm1Lex/Sik2tm1Lex
(involves: 129S/SvEvBrd)
increased inflammatory response J:229999
Sik3tm1a(EUCOMM)Hmgu/Sik3tm1a(EUCOMM)Hmgu
(C57BL/6N-Sik3tm1a(EUCOMM)Hmgu/Wtsi)
decreased alpha-beta T cell number J:211773
decreased CD4-positive NK T cell number J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased CD5-positive gamma-delta T cell number J:211773
decreased early germinal center B cell number J:211773
decreased effector memory T-helper cell number J:211773
decreased gamma-delta T cell number J:211773
decreased germinal center B cell number J:211773
decreased KLRG1-positive NK cell number J:211773
decreased KLRG1-positive T-helper cell number J:211773
decreased Ly6C-positive mature NK cell number J:211773
decreased memory-marker CD4-negative NK T cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
decreased NK cell number J:211773
decreased NK T cell number J:211773
decreased regulatory T cell number J:211773
decreased T cell number J:211773
decreased T-helper cell number J:211773
increased CD4-negative NK T cell number J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased eosinophil cell number J:211773
increased follicular B cell number J:211773
increased granulocyte number J:211773
increased KLRG1+ CD8 alpha-beta T cell number J:211773
increased KLRG1-positive CD4-negative NK T cell number J:211773
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased KLRG1-positive T-helper cell number J:211773
increased Ly6C-positive NK T cell number J:211773
increased memory-marker gamma-delta T cell number J:211773
increased memory-marker NK cell number J:211773
increased NK cell number J:211773
increased plasmacytoid dendritic cell number J:211773
Sin3btm1.2Rdp/Sin3btm1.2Rdp
(involves: 129 * C57BL/6 * FVB/N * SJL)
abnormal granulocyte differentiation J:154855
decreased granulocyte number J:154855
Sinhcaftm1.2Hmd/Sinhcaftm1.2Hmd
(involves: 129 * C57BL/6)
spleen hypoplasia J:313620
Sipa1tm1Nm/Sipa1+
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:97239
increased leukocyte cell number J:97239
Sipa1tm1Nm/Sipa1tm1Nm
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:97239
increased granulocyte number J:97239
increased leukocyte cell number J:97239
spleen hyperplasia J:97239
Sirpatm1b(EUCOMM)Hmgu/Sirpatm1b(EUCOMM)Hmgu
(C57BL/6N-Sirpatm1b(EUCOMM)Hmgu/Bay)
enlarged spleen J:211773
increased spleen weight J:211773
Sirpatm1Nog/Sirpatm1Nog
(involves: 129P2/OlaHsd * C57BL/6)
abnormal Langerhans cell physiology J:88694
abnormal macrophage physiology J:79592
decreased T cell number J:79592
Sirt1tm1b(EUCOMM)Wtsi/Sirt1+
(C57BL/6N-Sirt1tm1b(EUCOMM)Wtsi/H)
increased basophil cell number J:211773
Sirt1tm1Fwa/Sirt1tm1Fwa
(involves: 129/Sv * 129S6/SvEvTac)
immune system phenotype J:85542
Sirt1tm1Mcby/Sirt1tm1Mcby
(involves: 129)
decreased CD8-positive, alpha-beta T cell number J:81010
interstitial pneumonia J:81010
lung inflammation J:81010
Sirt1tm1Mcby/Sirt1tm1Mcby
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
decreased CD8-positive, alpha-beta T cell number J:81010
glomerulonephritis J:160869
increased anti-nuclear antigen antibody level J:160869
increased immunoglobulin level J:160869
interstitial pneumonia J:81010
lung inflammation J:81010
Sirt1tm1Mcby/Sirt1tm1Mcby
(involves: 129S1/Sv * 129X1/SvJ)
increased autoantibody level J:241633
Sirt1tm2.1Mcby/Sirt1tm2.1Mcby
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
enlarged spleen J:180628
Sirt3tm1.1Fwa/Sirt3tm1.1Fwa
(involves: 129S6/SvEvTac)
abnormal cytokine level J:178653
increased circulating interferon-gamma level J:178653
increased circulating interleukin-6 level J:178653
increased circulating interleukin-10 level J:178653
increased circulating interleukin-12 level J:178653
increased circulating tumor necrosis factor level J:178653
liver inflammation J:178653
Sirt6tm1Fwa/Sirt6tm1Fwa
(involves: 129S6/SvEvTac * 129X1/SvJ)
abnormal B cell differentiation J:112817
abnormal lymphopoiesis J:112817
colitis J:112817
decreased double-positive T cell number J:112817
decreased leukocyte cell number J:112817
spleen hypoplasia J:112817
Sirt6tm2.1Cxd/Sirt6tm2.1Cxd
(involves: 129S6/SvEvTac * NIH Black Swiss)
abnormal spleen physiology J:167023
Sirt6tm2.2Cxd/Sirt6tm2.2Cxd
(involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss)
abnormal spleen physiology J:167023
Sirt7tm1Evbo/Sirt7tm1Evbo
(involves: 129/Sv * C57BL/6)
abnormal cytokine level J:147652
increased granulocyte number J:147652
increased interleukin-4 secretion J:147652
increased interleukin-12 secretion J:147652
increased interleukin-13 secretion J:147652
Sirt7tm1Fwa/Sirt7tm1Fwa
(involves: 129S1/Sv)
increased macrophage cell number J:205529
liver inflammation J:205529
Sit1tm1Lsmn/Sit1tm1Lsmn
(B6.Cg-Sit1tm1Lsmn)
abnormal cytokine secretion J:100408
abnormal lymphocyte cell number J:100408
abnormal T cell differentiation J:100408
abnormal T-helper 1 cell differentiation J:100408
decreased CD4-positive, alpha-beta T cell number J:100408
decreased CD8-positive, alpha-beta T cell number J:100408
increased double-positive T cell number J:100408
increased interferon-gamma secretion J:100408
increased interleukin-2 secretion J:100408
increased mature gamma-delta T cell number J:100408
increased susceptibility to experimental autoimmune encephalomyelitis J:100408
increased T cell proliferation J:100408
increased tumor necrosis factor secretion J:100408
lymph node hypoplasia J:100408
thymus hyperplasia J:100408
Sit1tm1Lsmn/Sit1tm1Lsmn
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: C57BL/6 * C57BL/6J * DBA/2J)
abnormal CD8-positive, alpha beta T cell morphology J:100408
abnormal positive T cell selection J:100408
abnormal T cell differentiation J:100408
Sit1tm1Lsmn/Sit1tm1Lsmn
Tg(TcrLCMV)327Sdz/0

(involves: C57BL/6)
abnormal positive T cell selection J:100408
abnormal T cell selection J:100408
thymus hypoplasia J:100408
Six1em1(IMPC)Mbp/Six1+
(C57BL/6N-Six1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
decreased leukocyte cell number J:211773
enlarged spleen J:211773
small spleen J:211773
Six1tm1Kwk/Six1tm1Kwk
(involves: 129P2/OlaHsd * C57BL/6)
athymia J:104488
Six1tm1Mair/Six1tm1Mair
(involves: 129S2/SvPas)
athymia J:84417
Skap1Gt713Lex/Skap1Gt713Lex
(B6.129S5-Skap1Gt713Lex)
abnormal CD4-positive, alpha-beta T cell physiology J:126545
abnormal immune system physiology J:126545
abnormal T cell physiology J:126545
decreased interferon-gamma secretion J:126545
decreased interleukin-2 secretion J:126545
decreased T cell proliferation J:126545
immune system phenotype J:126545
Skap2Gt(VICTR20)21Lex/Skap2Gt(VICTR20)21Lex
(B6.129S5-Skap2Gt(VICTR20)21Lex)
abnormal B cell activation J:101373
abnormal dendritic cell antigen presentation J:151350
abnormal dendritic cell physiology J:151350
decreased B cell proliferation J:101373
decreased IgG2a level J:101373
decreased IgM level J:101373
decreased susceptibility to experimental autoimmune encephalomyelitis J:101373
Skida1tm1.1(KOMP)Wtsi/Skida1+
(C57BL/6N-Skida1tm1.1(KOMP)Wtsi/Ucd)
enlarged lymph nodes J:211773
enlarged thymus J:211773
Skida1tm1.1(KOMP)Wtsi/Skida1tm1.1(KOMP)Wtsi
(C57BL/6N-Skida1tm1.1(KOMP)Wtsi/Ucd)
enlarged thymus J:211773
small spleen J:211773
Skiltm1Spw/Skiltm1Spw
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
abnormal immune system cell morphology J:84554
abnormal immune system organ morphology J:84554
decreased T cell proliferation J:84554
enlarged spleen J:84554
Skiltm2Spw/Skiltm2Spw
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
decreased T cell proliferation J:84554
immune system phenotype J:84554
Skint1m1Tac/Skint1m1Tac
(FVB/NTac)
abnormal T cell differentiation J:139711
abnormal T cell morphology J:139711
Skint2em2Htaka/Skint2em2Htaka
(C57BL/6-Skint2em2Htaka)
decreased dendritic epidermal T cell number J:291989
skp/skp
(CXB5/ByJ-skp/GrsrJ)
thymus atrophy J:153578
Skp2tm1Kin/Skp2tm1Kin
(involves: 129P2/OlaHsd)
abnormal immunoglobulin V(D)J recombination J:168974
Sla2em1(IMPC)Ccpcz/Sla2em1(IMPC)Ccpcz
(C57BL/6N-Sla2em1(IMPC)Ccpcz/Ccpcz)
decreased NK cell number J:211773
Sla2tm1Amch/Sla2tm1Amch
(involves: 129)
immune system phenotype J:169170
Slatm1Weis/Slatm1Weis
(involves: 129 * C57BL/6)
abnormal double-positive T cell morphology J:71804
Slatm1Weis/Slatm1Weis
Sla2tm1Amch/Sla2tm1Amch

(involves: 129)
abnormal dendritic cell differentiation J:169170
abnormal dendritic cell physiology J:169170
decreased interleukin-12 secretion J:169170
decreased tumor necrosis factor secretion J:169170
Slatm1Weis/Slatm1Weis
Tg(DO11.10)10Dlo/0

(involves: 129 * BALB/c * C3H * C57BL/6)
abnormal positive T cell selection J:71804
abnormal T cell differentiation J:71804
Slatm1Weis/Slatm1Weis
Zap70tm1Weis/Zap70tm1Weis

(involves: 129 * 129X1/SvJ * C57BL/6)
abnormal T cell differentiation J:71804
decreased CD4-positive, alpha-beta T cell number J:71804
Slamf1tm1Cpt/Slamf1tm1Cpt
(B6.129S4-Slamf1tm1Cpt)
abnormal cytokine secretion J:90484
abnormal macrophage physiology J:90484
increased susceptibility to parasitic infection J:90484
Slamf1tm1Cpt/Slamf1tm1Cpt
(C.129S4-Slamf1tm1Cpt)
abnormal cytokine secretion J:90484
abnormal macrophage physiology J:90484
Slamf1tm1Cpt/Slamf1tm1Cpt
Tg(DO11.10)10Dlo/Tg(DO11.10)10Dlo

(involves: BALB/c * C3H * C57BL/6)
abnormal cytokine secretion J:90484
Slamf1tm1Oono/Slamf1tm1Oono
(B6.129-Slamf1tm1Oono)
increased susceptibility to Paramyxoviridae infection J:117810
Slamf1tm1Vei/Slamf1tm1Vei
(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:133047, J:93886
immune system phenotype J:133047
Slamf6tm1Dhow/Slamf6tm1Dhow
(involves: 129/Sv * C57BL/6)
abnormal neutrophil physiology J:98995
abnormal T-helper 2 physiology J:98995
decreased interleukin-4 secretion J:98995
decreased susceptibility to parasitic infection J:98995
impaired granulocyte bactericidal activity J:98995
increased circulating interleukin-12b level J:98995
increased circulating interleukin-16 level J:98995
increased circulating tumor necrosis factor level J:98995
increased susceptibility to bacterial infection J:98995
increased susceptibility to bacterial infection induced morbidity/mortality J:98995
Slamf6tm1Lex/Slamf6tm1Lex
(B6.129S5-Slamf6tm1Lex)
immune system phenotype J:187429
Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6 * C57BL/6J)
immune system phenotype J:187431
Slamf7tm1Vei/Slamf7tm1Vei
(involves: 129S1/Sv * 129X1/SvJ)
impaired natural killer cell mediated cytotoxicity J:145969
Slamf8tm1Mill/Slamf8tm1Mill
(involves: BALB/c)
abnormal macrophage physiology J:188963
increased susceptibility to bacterial infection J:188963
Slamf9em1Isha/Slamf9em1Isha
(involves: C57BL/6)
abnormal plasmacytoid dendritic cell physiology J:279164
decreased susceptibility to experimental autoimmune encephalomyelitis J:279164
increased plasmacytoid dendritic cell number J:279164
Slc1a5tm1Tac/Slc1a5tm1Tac
(involves: 129S/SvEv * C57BL/6)
abnormal T cell physiology J:254980
abnormal T-helper 1 cell differentiation J:254980
abnormal T-helper 2 cell differentiation J:254980
abnormal T-helper 17 cell differentiation J:254980
decreased B cell number J:254980
decreased CD4-positive, alpha-beta memory T cell number J:254980
decreased susceptibility to experimental autoimmune encephalomyelitis J:254980
decreased T helper 1 cell number J:254980
decreased T-helper 17 cell number J:254980
immune system phenotype J:254980
increased CD4-positive, alpha-beta T cell number J:254980
Slc2a4tm1Mch/Slc2a4+
(involves: 129/Sv * C57BL/6J * CD-1 * SJL)
heart inflammation J:43650
Slc2a5tm1b(EUCOMM)Wtsi/Slc2a5tm1b(EUCOMM)Wtsi
(C57BL/6N-Slc2a5tm1b(EUCOMM)Wtsi/Ieg)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Slc2a6em1Kusu/Slc2a6em1Kusu
(involves: C57BL/6JCrlj)
abnormal macrophage physiology J:270487
increased circulating tumor necrosis factor level J:270487
increased susceptibility to endotoxin shock J:270487
Slc2a9tm1.2Thor/Slc2a9tm1.2Thor
(involves: C57BL/6 * C57BL/6N)
kidney inflammation J:153089
tubulointerstitial nephritis J:153089
Slc2a10G128E/Slc2a10G128E
(C3HeB/FeJ-Slc2a10G128E)
abnormal spleen morphology J:161835
Slc3a1pbl/Slc3a1pbl
(C3HeB/FeJ-Slc3a1pbl)
tubulointerstitial nephritis J:85461
Slc3a1pbl/Slc3a1pbl
(involves: C3HeB/FeJ * MRL/MpJ)
kidney inflammation J:85461
Slc3a1tm1.1(KOMP)Vlcg/Slc3a1tm1.1(KOMP)Vlcg
(C57BL/6N-Slc3a1tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased eosinophil cell number J:211773
increased spleen weight J:211773
Slc3a2tm1.1Merl/Slc3a2+
Tg(Vil1-cre)997Gum/0

(B6.Cg-Slc3a2tm1.1Merl Tg(Vil1-cre)997Gum)
decreased susceptibility to induced colitis J:173946
Slc3a2tm1.1Yait/Slc3a2tm1.1Yait
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6NCrSlc)
abnormal macrophage antigen presentation J:188365
abnormal macrophage differentiation J:188365
abnormal macrophage morphology J:188365
abnormal macrophage physiology J:188365
impaired macrophage phagocytosis J:188365
Slc4a1tm1Ahc/Slc4a1tm1Ahc
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal immune system organ morphology J:35637
enlarged spleen J:35637
Slc4a1tm1Dmb/Slc4a1tm1Dmb
(involves: 129S6/SvEvTac)
abnormal splenic cell ratio J:145243
Slc4a1tm1Llp/Slc4a1tm1Llp
(involves: 129S4/SvJae * C57BL/6J)
enlarged spleen J:35487
Slc4a1tm1Phsl/Slc4a1tm1Phsl
(involves: 129 * 129S6/SvEvTac * Black Swiss)
enlarged spleen J:152245
Slc4a2tm1Ges/Slc4a2tm1Ges
(involves: 129S6/SvEvTac)
abnormal osteoclast morphology J:193823
abnormal osteoclast physiology J:193823
Slc4a2tm2Ges/Slc4a2tm2Ges
Ctsktm1(cre)Ska/Ctsk+

(involves: C57BL/6NCrlj * CBA/JNCrlj)
abnormal osteoclast morphology J:193823
abnormal osteoclast physiology J:193823
Slc4a2tm2Ges/Slc4a2tm2Ges
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal osteoclast morphology J:193823
abnormal osteoclast physiology J:193823
Slc4a4tm1.1Slin/Slc4a4tm1.1Slin
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
enlarged spleen J:186877
increased spleen weight J:186877
Slc4a4tm1Ges/Slc4a4tm1Ges
(involves: 129S6/SvEvTac * Black Swiss)
decreased lymphocyte cell number J:120867
disorganized spleen B cell follicle J:120867
enlarged spleen J:120867
increased spleen red pulp amount J:120867
increased spleen white pulp amount J:120867
Slc4a10tm1b(KOMP)Wtsi/Slc4a10tm1b(KOMP)Wtsi
(C57BL/6N-Slc4a10tm1b(KOMP)Wtsi/H)
small spleen J:211773
Slc5a2m2Btlr/Slc5a2m2Btlr
(C57BL/6J-Slc5a2m2Btlr)
increased susceptibility to induced colitis J:265117
increased tumor necrosis factor secretion J:265117
Slc5a2tm1Lex/Slc5a2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased susceptibility to autoimmune diabetes J:195941
Slc5a6tm1.1Said/Slc5a6tm1.1Said
Tg(Vil1-cre)997Gum/?

(involves: C57BL/6)
immune system phenotype J:194700
Slc5a6tm1.1Said/Slc5a6tm1.1Said
Tg(Vil1-cre/ERT2)23Syr/0

(involves: C57BL/6 * DBA/2)
cecum inflammation J:307482
small intestinal inflammation J:307482
Slc5a7tm1a(KOMP)Wtsi/Slc5a7tm1a(KOMP)Wtsi
(C57BL/6N-Slc5a7tm1a(KOMP)Wtsi/Wtsi)
blood in lymph vessels J:239583
Slc6a6em1(IMPC)Mbp/Slc6a6em1(IMPC)Mbp
(C57BL/6N-Slc6a6em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
Slc6a8tm1.2Lbar/Y
(involves: 129 * 129S1/Sv * C57BL/6J * C57BL/6N)
microgliosis J:238578
Slc6a14tm1Gana/Slc6a14tm1Gana
(Not Specified)
abnormal circulating chemokine level J:226105
abnormal circulating cytokine level J:226105
decreased circulating interleukin-1 alpha level J:226105
decreased circulating interleukin-4 level J:226105
Slc6a14tm1Gana/Slc6a14tm1Gana
Tg(MMTV-PyVT)634Mul/0

(Not Specified)
abnormal immunoglobulin level J:226105
Slc7a2tm1Clm/Slc7a2tm1Clm
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal immune system physiology J:69414
Slc7a5em1(IMPC)H/Slc7a5+
(C57BL/6NTac-Slc7a5em1(IMPC)H/H)
increased basophil cell number J:211773
Slc7a7em1Lbu/Slc7a7em1Lbu
(involves: 129/SvEv * C57BL/6)
abnormal spleen germinal center morphology J:293773
decreased lymphocyte cell number J:293773
decreased spleen weight J:293773
increased neutrophil cell number J:293773
increased spleen red pulp amount J:293773
Slc7a7Gt(OST41878)Lex/Slc7a7Gt(OST41878)Lex
(B6.129S-Slc7a7Gt(OST41878)Lex)
increased spleen weight J:125847
Slc7a9tm1Nune/Slc7a9tm1Nune
(involves: 129P2/OlaHsd * C57BL/6J)
tubulointerstitial nephritis J:85462
Slc7a11m1Mtka/Slc7a11m1Mtka
(C57BL/6-Slc7a11m1Mtka)
abnormal dendritic cell physiology J:159323
abnormal macrophage physiology J:159323
immune system phenotype J:159323
Slc9a2tm1Ges/Slc9a2tm1Ges
(involves: 129X1/SvJ * Black Swiss)
stomach inflammation J:65754
Slc9a4tm1Ges/Slc9a4tm1Ges
(involves: 129S6/SvEvTac * Black Swiss)
stomach inflammation J:98566
Slc9a6tm1Dgen/Y
(B6.129P2-Slc9a6tm1Dgen/J)
microgliosis J:262453
Slc9a8m1Btlr/Slc9a8m1Btlr
(C57BL/6J-Slc9a8m1Btlr)
increased susceptibility to induced colitis J:267481
Slc9b1em1(IMPC)Mbp/Slc9b1em1(IMPC)Mbp
(C57BL/6N-Slc9b1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Slc11a1em1(IMPC)Mbp/Slc11a1em1(IMPC)Mbp
(C57BL/6N-Slc11a1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Slc11a1r/Slc11a1r
(C3H/HeJ-Slc11a1r)
decreased susceptibility to bacterial infection J:35004
Slc11a1r/Slc11a1r
(129/Sv)
decreased susceptibility to bacterial infection J:81412
Slc11a1r/Slc11a1s
((129/Sv x BALB/c)F1)
decreased susceptibility to bacterial infection J:28278
Slc11a1s/Slc11a1r
((129/Sv x C57BL/6J)F1)
abnormal susceptibility to bacterial infection J:81412
Slc11a1s/Slc11a1s
(C57BL/6J)
increased susceptibility to bacterial infection J:81412
Slc11a1s/Slc11a1s
(BALB/c)
increased susceptibility to bacterial infection J:28278
Slc11a1tm1Mcg/Slc11a1s
(involves: 129S4/SvJae * BALB/c)
increased susceptibility to bacterial infection J:28278
Slc11a1tm1Mcg/Slc11a1tm1Mcg
(involves: 129S4/SvJae * BALB/c)
increased susceptibility to bacterial infection J:28278
Slc11a2mk/Slc11a2mk
(MK/ReJ)
increased spleen weight J:5167
Slc11a2mk/Slc11a2mk
(SEC.Cg-Slc11a2mk)
increased spleen weight J:5167
Slc11a2tm2Nca/Slc11a2tm2Nca
Tg(Vil1-cre)20Syr/?

(involves: 129S6.129S4-Slc11a2tm2Nca * C57BL/6 * DBA/2)
abnormal spleen morphology J:98088
decreased spleen iron level J:98088
enlarged spleen J:98088
increased spleen red pulp amount J:98088
Slc12a1urehr3/Slc12a1urehr3
(involves: C3HeB/FeJ)
pyelitis J:159994
pyelonephritis J:159994
Slc12a2em1Dlp/Slc12a2+
(involves: C57BL/6J * DBA/2J)
increased susceptibility to bacterial infection J:285398
Slc12a2em1Dlp/Slc12a2em1Dlp
(involves: C57BL/6J * DBA/2J)
increased lymphocyte cell number J:285398
increased susceptibility to bacterial infection J:285398
large intestinal inflammation J:285398
Slc12a5em1(IMPC)Mbp/Slc12a5+
(C57BL/6N-Slc12a5em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Slc13a3tm1b(KOMP)Wtsi/Slc13a3tm1b(KOMP)Wtsi
(C57BL/6N-Slc13a3tm1b(KOMP)Wtsi/Ucd)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Slc13a5tm1b(EUCOMM)Hmgu/Slc13a5tm1b(EUCOMM)Hmgu
(C57BL/6N-Slc13a5tm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Slc14a1tm1Ask/Slc14a1tm1Ask
(involves: C57BL/6J * CD-1)
decreased spleen weight J:125840
Slc15a3tm1a(KOMP)Wtsi/Slc15a3tm1a(KOMP)Wtsi
(C57BL/6N-Slc15a3tm1a(KOMP)Wtsi)
abnormal myeloid dendritic cell morphology J:210445
Slc15a3tm1b(KOMP)Wtsi/Slc15a3tm1b(KOMP)Wtsi
(C57BL/6N-Slc15a3tm1b(KOMP)Wtsi/H)
increased monocyte cell number J:211773
Slc15a4m1Btlr/Slc15a4m1Btlr
(C57BL/6J-Slc15a4m1Btlr)
abnormal interferon secretion J:166600
decreased interleukin-6 secretion J:166600
decreased interleukin-12 secretion J:166600
decreased tumor necrosis factor secretion J:166600
Slc15a4tm1Tkyo/Slc15a4tm1Tkyo
(involves: C57BL/6)
abnormal circulating cytokine level J:270965
abnormal cytokine secretion J:270965
decreased circulating interleukin-1 beta level J:270965
decreased circulating interleukin-6 level J:270965
decreased interferon-beta secretion J:270965
decreased interleukin-1 beta secretion J:270965
decreased interleukin-6 secretion J:270965
decreased interleukin-12 secretion J:270965
decreased interleukin-12b secretion J:270965
decreased interleukin-15 secretion J:270965
decreased interleukin-18 secretion J:270965
decreased susceptibility to induced colitis J:270965
decreased tumor necrosis factor secretion J:270965
Slc17a1em1(IMPC)J/Slc17a1em1(IMPC)J
(C57BL/6NJ-Slc17a1em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Slc17a8em1(IMPC)Mbp/Slc17a8em1(IMPC)Mbp
(C57BL/6N-Slc17a8em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Slc19a1tm1Gold/Slc19a1tm1Gold
(involves: 129/Sv * C57BL/6 * SJL)
abnormal lymphopoiesis J:68666
decreased lymphocyte cell number J:68666
small spleen J:68666
small thymus J:68666
Slc19a2tm1Gelb/Slc19a2tm1Gelb
(involves: 129X1/SvJ)
abnormal myelopoiesis J:79974
Slc19a3tm1Said/Slc19a3tm1Said
(involves: C57BL/6)
chronic liver inflammation J:170952
kidney inflammation J:170952
Slc20a1tm1.1Lbek/Slc20a1tm1.1Lbek
Tg(Mx1-cre)1Cgn/0

(involves: 129S2/SvPas * C57BL/6 * C57BL/6J * CBA)
enlarged spleen J:194198
increased leukocyte cell number J:194198
intermingled spleen red and white pulp J:194198
spleen hyperplasia J:194198
Slc20a1tm1Lbek/Slc20a1tm1Lbek
(involves: 129S2/SvPas * C57BL/6J)
abnormal spleen morphology J:194198
enlarged spleen J:194198
increased spleen weight J:157997
Slc20a2tm1a(EUCOMM)Wtsi/Slc20a2tm1a(EUCOMM)Wtsi
(C57BL/6NTac-Slc20a2tm1a(EUCOMM)Wtsi/Ieg)
microgliosis J:223197
Slc22a4tm1Atsu/Slc22a4tm1Atsu
(involves: C57BL/6J)
intestinal inflammation J:207006
Slc22a6tm1Dgen/Slc22a6tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6)
increased thymus weight J:101679
Slc22a29em1(IMPC)Mbp/Slc22a29em1(IMPC)Mbp
(C57BL/6N-Slc22a29em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Slc23a4tm1a(KOMP)Wtsi/Slc23a4tm1a(KOMP)Wtsi
(C57BL/6N-2010107G12Riktm1a(KOMP)Wtsi/Wtsi)
decreased leukocyte cell number J:175295
Slc24a3em#Ebje/Slc24a3em#Ebje
(C57BL/6J-Slc24a3em#Ebje)
increased susceptibility to induced colitis J:308448
Slc24a4tm1b(KOMP)Wtsi/Slc24a4+
(C57BL/6N-Slc24a4tm1b(KOMP)Wtsi/H)
enlarged thymus J:211773
Slc25a17Gt(XB686)Byg/Slc25a17Gt(XB686)Byg
(involves: 129P2/OlaHsd * C57BL/6 * Swiss Webster)
abnormal Kupffer cell morphology J:291257
liver inflammation J:291257
Slc25a37tm1.1Kapl/Slc25a37tm1.2Kapl
Speer6-ps1Tg(Alb-cre)21Mgn/?

(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCr * DBA)
enlarged spleen J:173284
Slc25a37tm1.1Kapl/Slc25a37tm1.2Kapl
Tg(Mx1-cre)1Cgn/?

(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCr * CBA)
abnormal B cell morphology J:173284
abnormal lymphocyte morphology J:173284
abnormal spleen morphology J:173284
abnormal T cell morphology J:173284
enlarged spleen J:173284
Slc25a42em1(IMPC)J/Slc25a42+
(C57BL/6NJ-Slc25a42em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Slc25a46atc/Slc25a46atc
(B6.Cg-Slc25a46atc)
decreased spleen weight J:242350
decreased thymus weight J:242350
microgliosis J:242350
spleen hypoplasia J:242350
thymus hypoplasia J:242350
Slc26a1tm1Mark/Slc26a1tm1Mark
(involves: 129X1/SvJ * CD-1)
kidney inflammation J:158567
Slc26a4m2Btlr/Slc26a4m2Btlr
(C57BL/6J-Slc26a4m2Btlr)
increased susceptibility to induced colitis J:236690
Slc26a9em1(IMPC)Mbp/Slc26a9+
(C57BL/6N-Slc26a9em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Slc28a3em1(IMPC)H/Slc28a3em1(IMPC)H
(C57BL/6N-Slc28a3em1(IMPC)H/H)
increased large unstained cell number J:211773
increased monocyte cell number J:211773
Slc29a1tm2Msg/Slc29a1tm2Msg
Eportm1.1(EGFP/icre)Uk/Epor+

(involves: 129X1/SvJ * BALB/cJ)
decreased interleukin-6 secretion J:244602
Slc29a2Gt(OST207791)Lex/Slc29a2Gt(OST207791)Lex
(involves: 129S5/SvEvBrd)
decreased interleukin-6 secretion J:203572
Slc29a3em1(IMPC)Mbp/Slc29a3em1(IMPC)Mbp
(C57BL/6NCrl-Slc29a3em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased spleen weight J:211773
small thymus J:211773
Slc29a3em1(IMPC)Wtsi/Slc29a3em1(IMPC)Wtsi
(C57BL/6N-Slc29a3em1(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Slc29a3tm1Lex/Slc29a3tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal macrophage morphology J:179286
abnormal macrophage physiology J:179286
enlarged lymph nodes J:179286
enlarged spleen J:179286
immune system phenotype J:179286
increased macrophage apoptosis J:179286
increased macrophage cell number J:179286
increased susceptibility to bacterial infection J:179286
increased susceptibility to bacterial infection induced morbidity/mortality J:179286
myeloid hyperplasia J:179286
Slc30a2tm1Kgna/Slc30a2tm1Kgna
(involves: 129 * C57BL/6)
abnormal macrophage physiology J:264481
Slc30a4em1(IMPC)Tcp/Slc30a4em1(IMPC)Tcp
(C57BL/6NCrl-Slc30a4em1(IMPC)Tcp/Tcp)
small thymus J:211773
Slc30a4lm/Slc30a4lm
(C57BL/6J-Slc30a4lm)
dermatitis J:5911, J:7690
Slc31a1tm2Djt/Slc31a1tm2Djt
Tg(Vil1-cre)997Gum/0

(involves: 129 * C57BL/6 * FVB/N * SJL)
decreased spleen weight J:129741
Slc33a1tm1.1Lpu/Slc33a1+
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal circulating cytokine level J:211266
abnormal cytokine secretion J:211266
abnormal T cell activation J:211266
brain inflammation J:211266
conjunctivitis J:211266
decreased B cell number J:211266
dermatitis J:211266
immune system phenotype J:211266
increased B cell number J:211266
increased circulating interleukin-17 level J:211266
increased circulating interleukin-18 level J:211266
increased inflammatory response J:211266
increased interferon-gamma secretion J:211266
increased interleukin-4 secretion J:211266
increased interleukin-17 secretion J:211266
increased neutrophil cell number J:211266
increased susceptibility to infection J:211266
microgliosis J:211266
preputial gland inflammation J:211266
prostate gland inflammation J:211266
salivary gland inflammation J:211266
stomach inflammation J:211266
urinary bladder inflammation J:211266
Slc35c1tm1Cknr/Slc35c1tm1Cknr
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal leukocyte adhesion J:121151
abnormal lymph node primary follicle morphology J:121151
impaired leukocyte tethering or rolling J:121151
increased eosinophil cell number J:121151
increased leukocyte cell number J:121151
increased lymphocyte cell number J:121151
increased monocyte cell number J:121151
increased neutrophil cell number J:121151
lymph node hypoplasia J:121151
Slc37a2em1(IMPC)Mbp/Slc37a2em1(IMPC)Mbp
(C57BL/6NCrl-Slc37a2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged spleen J:211773
Slc37a2tm1Dgen/Slc37a2tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal macrophage physiology J:311521
increased interleukin-1 beta secretion J:311521
increased interleukin-6 secretion J:311521
increased susceptibility to endotoxin shock J:311521
increased tumor necrosis factor secretion J:311521
Slc37a4tm1Jyc/Slc37a4tm1Jyc
(involves: 129S4/SvJae * C57BL/6)
abnormal chemokine secretion J:86005
abnormal inflammatory response J:86005
abnormal myelopoiesis J:86005
abnormal neutrophil physiology J:86005
abnormal spleen morphology J:86005
absent spleen white pulp J:86005
decreased inflammatory response J:86005
decreased lymphocyte cell number J:86005
decreased neutrophil cell number J:86005
impaired neutrophil chemotaxis J:86005
small spleen J:86005
Slc38a2tm1a(KOMP)Wtsi/Slc38a2+
(C57BL/6N-Slc38a2tm1a(KOMP)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Slc38a7em1(IMPC)Ccpcz/Slc38a7em1(IMPC)Ccpcz
(C57BL/6NCrl-Slc38a7em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Slc38a8em1Cya/Slc38a8em1Cya
(C57BL/6J-Slc38a8em1Cya)
decreased susceptibility to viral infection J:336781
decreased susceptibility to viral infection induced morbidity/mortality J:336781
Slc39a3tm1Gka/Slc39a3tm1Gka
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:99161
decreased double-positive T cell number J:99161
increased CD4-positive, alpha-beta T cell number J:99161
Slc39a5tm1.1Gka/Slc39a5tm1.1Gka
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
increased susceptibility to induced pancreatitis J:209760
Slc39a5tm1Gka/Slc39a5tm1Gka
Tg(Cela1-cre/ERT)1Lgdn/0

(involves: 129P2/OlaHsd * C57BL/6)
increased susceptibility to induced pancreatitis J:209760
Slc39a10tm1.1Tfk/Slc39a10tm1.1Tfk
Tg(Foxn1-cre)8Ghr/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
increased thymocyte apoptosis J:254216
thymus hypoplasia J:254216
Slc40a1ffe/Slc40a1+
(either: (involves: 129X1/SvJ * C57BL/6J) or (involves: C3H/HeJ * C57BL/6J))
abnormal macrophage physiology J:118592
Slc40a1Pcm/Slc40a1+
(A.Cg-Slc40a1Pcm)
abnormal spleen development J:98335
abnormal spleen physiology J:98335
decreased spleen iron level J:98335
increased splenocyte apoptosis J:98335
small spleen J:98335
Slc40a1Pcm/Slc40a1Pcm
(A.Cg-Slc40a1Pcm)
abnormal spleen development J:98335
decreased spleen iron level J:98335
increased splenocyte apoptosis J:98335
small spleen J:98335
Slc40a1tm1.1Mmfe/Slc40a1+
(involves: 129P2/OlaHsd * C57BL/6)
decreased spleen iron level J:215585
Slc40a1tm1.1Mmfe/Slc40a1tm1.1Mmfe
(involves: 129P2/OlaHsd * C57BL/6)
decreased spleen iron level J:215585
Slc40a1tm1Nca/Slc40a1+
(involves: 129S4/SvJae * 129S6/SvEvTac)
increased spleen iron level J:129846
Slc40a1tm2Nca/Slc40a1tm2Nca
Tg(Vil1-cre/ERT2)23Syr/0

(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * DBA/2)
decreased spleen iron level J:129846
Slc43a2Gt(258C1)Cmhd/Slc43a2Gt(258C1)Cmhd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1)
liver inflammation J:237439
Slc46a2tm1Moki/Slc46a2tm1Moki
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
thymus hypoplasia J:140121
Slc48a1em1Ih/Slc48a1em1Ih
(involves: 129 * C57BL/6J)
abnormal macrophage morphology J:282829
abnormal macrophage physiology J:282829
abnormal spleen morphology J:282829
decreased macrophage cell number J:282829
enlarged spleen J:282829
increased spleen iron level J:282829
Slc51bem1(IMPC)Mbp/Slc51bem1(IMPC)Mbp
(C57BL/6NCrl-Slc51bem1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Slc52a2tm1.1(KOMP)Vlcg/Slc52a2+
(C57BL/6N-Slc52a2tm1.1(KOMP)Vlcg/Ucd)
enlarged lymph nodes J:211773
Slco1a5tm1Lex/Slco1a5tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
abnormal CD8-positive, alpha beta T cell morphology J:103485
increased B cell number J:103485
Sle1NZM2410/Aeg/Sle1NZM2410/Aeg
Sle3NZM2410/Aeg/Sle3NZM2410/Aeg

(B6;NZM-Sle1NZM2410/Aeg Sle2NZM2410/Aeg Sle3NZM2410/Aeg/LmoJ)
abnormal marginal zone B cell physiology J:138314
increased marginal zone B cell number J:138314
Sle1NZW/Sle1NZW
Sles1NZW/Sles1NZW

(involves: C57BL/6 * NZW)
abnormal T cell physiology J:100678
decreased susceptibility to systemic lupus erythematosus J:100678
Sle1NZW/Sle1NZW
Tg(Tnfsf13b)1Fma/0

(involves: C57BL/6 * DBA/2J * NZW)
glomerulonephritis J:134128
increased B cell number J:134128
increased IgG level J:134128
increased IgM level J:134128
increased marginal zone B cell number J:134128
increased susceptibility to systemic lupus erythematosus J:134128
Sle1aC57BL/6J/Sle1aNZM2410/J
(involves: C57BL/6J * NZM2410/J)
increased anti-chromatin antibody level J:67544
Sle1aNZM2410/J/Sle1aNZM2410/J
(involves: C57BL/6J * NZM2410/J)
increased anti-chromatin antibody level J:67544
Sle1bC57BL/6J/Sle1bNZM2410/J
(involves: C57BL/6J * NZM2410/J)
increased anti-chromatin antibody level J:67544
Sle1bNZM2410/J/Sle1bNZM2410/J
(involves: C57BL/6J * NZM2410/J)
increased anti-chromatin antibody level J:67544
Sle1cC57BL/6J/Sle1cNZM2410/J
(involves: C57BL/6J * NZM2410/J)
increased anti-chromatin antibody level J:67544
Sle1cNZB/Sle1cNZM2410/J
(involves: C57BL/6J * NZB * NZM2410/J)
glomerulonephritis J:145133
increased autoantibody level J:145133
Sle1cNZM2410/J/Sle1cNZM2410/J
(involves: C57BL/6J * NZM2410/J)
increased anti-chromatin antibody level J:67544
Sle2NZM2410/Aeg/Sle2NZM2410/Aeg
(involves: C57BL/6J * NZM2410/Aeg)
glomerulonephritis J:25006
Sle3NZM2410/Aeg/?
(involves: C57BL/6J * NZM2410/Aeg)
glomerulonephritis J:52863
increased IgG level J:52863
increased IgM level J:52863
Sle6NZW/Sle6NZW
(involves: C57BL/6 * NZW)
increased susceptibility to systemic lupus erythematosus J:57246
Sle7BXSB/J/Sle7BXSB/J
(involves: BXSB/J * C57BL/10Ola)
glomerulonephritis J:60445
Sle8BXSB/J/Sle8BXSB/J
(involves: BXSB/J * C57BL/10Ola)
glomerulonephritis J:60445
Sle9BXSB/J/Sle9BXSB/J
(involves: BXSB/J * C57BL/10Ola)
increased anti-nuclear antigen antibody level J:60445
Sle10BXSB/J/Sle10BXSB/J
(involves: BXSB/J * C57BL/10Ola)
enlarged lymph nodes J:60445
Sle11BXSB/J/Sle11BXSB/J
(involves: BXSB/J * C57BL/10Ola)
increased IgG3 level J:60445
Sle12C57BL/6J/Sle12C57BL/6J
(involves: C57BL/6J * NZM2410/Aeg)
glomerulonephritis J:52863
Sle12C57BL/6J/Sle12NZM2410/Aeg
(involves: C57BL/6J * NZM2410/Aeg)
glomerulonephritis J:52863
Sle12NZM2410/Aeg/Sle12NZM2410/Aeg
(involves: C57BL/6J * NZM2410/Aeg)
glomerulonephritis J:52863
Sle16129S6/SvEvTac/?
(involves: 129X1/Sv * C57BL/6)
abnormal immune serum protein physiology J:93297
Sle16129S6/SvEvTac/Sle16129S6/SvEvTac
(B6.129-Sle16129S6/SvEvTac)
increased autoantibody level J:122132
increased susceptibility to systemic lupus erythematosus J:122132
Sle17129S6/SvEvTac/?
(involves: 129S6/SvEvTac * C57BL/6)
abnormal immune serum protein physiology J:93297
Sle18C57BL/6/?
(involves: 129X1/Sv * C57BL/6)
abnormal immune serum protein physiology J:93297
Sles1C57BL/6/Sles1C57BL/6
(involves: C57BL/6 * NZW)
increased susceptibility to systemic lupus erythematosus J:57246
Sles1C57BL/6/Sles1NZW
(involves: C57BL/6 * NZW)
abnormal immune system physiology J:57246
Sles1NZW/Sles1NZW
(involves: C57BL/6 * NZW)
decreased susceptibility to systemic lupus erythematosus J:57246
Sles2C57BL/6/Sles2C57BL/6
(involves: C57BL/6 * NZW)
increased susceptibility to systemic lupus erythematosus J:57246
Sles2C57BL/6/Sles2NZW
(involves: C57BL/6 * NZW)
increased susceptibility to systemic lupus erythematosus J:57246
Sles2NZW/Sles2NZW
(involves: C57BL/6 * NZW)
decreased susceptibility to systemic lupus erythematosus J:57246
Sles3C57BL/6/Sles3C57BL/6
(involves: C57BL/6 * NZW)
increased susceptibility to systemic lupus erythematosus J:57246
Sles3C57BL/6/Sles3NZW
(involves: C57BL/6 * NZW)
increased susceptibility to systemic lupus erythematosus J:57246
Sles3NZW/Sles3NZW
(involves: C57BL/6 * NZW)
decreased susceptibility to systemic lupus erythematosus J:57246
Sles4C57BL/6/Sles4C57BL/6
(involves: C57BL/6 * NZW)
increased susceptibility to systemic lupus erythematosus J:57246
Sles4C57BL/6/Sles4NZW
(involves: C57BL/6 * NZW)
increased susceptibility to systemic lupus erythematosus J:57246
Sles4NZW/Sles4NZW
(involves: C57BL/6 * NZW)
decreased susceptibility to systemic lupus erythematosus J:57246
Slfn1tm1Aki/Slfn1tm1Aki
(Not Specified)
immune system phenotype J:158985, J:258797
Slfn2m1Btlr/Slfn2m1Btlr
(C57BL/6J-Slfn2m1Btlr)
abnormal leukocyte physiology J:158985
abnormal T cell activation J:158985
abnormal T cell proliferation J:158985
decreased CD4-positive, alpha-beta T cell number J:158985
decreased CD8-positive, alpha-beta T cell number J:158985
decreased monocyte cell number J:158985
decreased T cell proliferation J:158985
increased neutrophil cell number J:158985
increased susceptibility to bacterial infection J:158985
increased susceptibility to bacterial infection induced morbidity/mortality J:158985
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:158985
increased susceptibility to Riboviria infection J:158985
increased T cell apoptosis J:158985
Slfn2m2Btlr/Slfn2m2Btlr
(C57BL/6J-Slfn2m2Btlr)
decreased IgG level J:234262
decreased response to antigen J:234262
impaired humoral immune response J:234262
Slfn3tm1Aki/Slfn3tm1Aki
(Not Specified)
immune system phenotype J:158985, J:258797
Slfn4tm1c(EUCOMM)Wtsi/Slfn4tm1c(EUCOMM)Wtsi
Gli1tm3(cre/ERT2)Alj/Gli1+

(involves: 129S6/SvEvTac * Black Swiss * C57BL/6 * Swiss Webster)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:337060
abnormal interleukin level J:337060
abnormal tumor necrosis factor level J:337060
decreased susceptibility to bacterial infection J:337060
Slfn5tm1Aki/Slfn5tm1Aki
(Not Specified)
immune system phenotype J:258797
Slfn8tm1Aki/Slfn8tm1Aki
(involves: 129X1/SvJ * C57BL/6)
decreased interferon-gamma secretion J:258797
decreased interleukin-1 beta secretion J:258797
decreased interleukin-6 secretion J:258797
decreased interleukin-17 secretion J:258797
decreased susceptibility to experimental autoimmune encephalomyelitis J:258797
immune system phenotype J:258797
Slfn14em1Nvm/Slfn14+
(C57BL/6J-Slfn14em1Nvm)
enlarged spleen J:325381
increased spleen weight J:325381
Slit2em1(IMPC)Mbp/Slit2+
(C57BL/6N-Slit2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Slitrk5em1(IMPC)Mbp/Slitrk5em1(IMPC)Mbp
(C57BL/6N-Slitrk5em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Slpd1NZB/BlNJ/Slpd1NZB/BlNJ
(involves: DBA/2J * NZB/BlNJ)
increased B cell proliferation J:124364
Slpitm1Ktak/Slpitm1Ktak
(B6.129P2-Slpitm1Ktak)
increased susceptibility to bacterial infection J:132933
Slpitm1Nkw/Slpitm1Nkw
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:82214
increased B cell proliferation J:82214
increased interleukin-6 secretion J:82214
increased susceptibility to endotoxin shock J:82214
Slu7tm1a(KOMP)Wtsi/Slu7+
(C57BL/6N-Slu7tm1a(KOMP)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Slurp2tm1Lex/Slurp2tm1Lex
(involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6)
immune system phenotype J:231067
Slx4tm1a(EUCOMM)Wtsi/Slx4tm1a(EUCOMM)Wtsi
(C57BL/6N-Slx4tm1a(EUCOMM)Wtsi)
abnormal lymphopoiesis J:168567
decreased leukocyte cell number J:168567
Smad2tm3Rob/Smad2tm3Rob
Smad3tm1Xfw/Smad3tm1Xfw

(involves: 129/Sv * 129S/SvEv * C57BL/6 * ICR)
osteoarthritis J:95374
Smad3tm1Cxd/Smad3tm1Cxd
(either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * NIH Black Swiss))
abnormal immune system morphology J:53510
abnormal T cell activation J:53510
abnormal T cell physiology J:53510
abnormal thymus involution J:53510
colitis J:53510
enlarged lymph nodes J:53510
enlarged mesenteric lymph nodes J:53510
impaired neutrophil chemotaxis J:53510
increased inflammatory response J:53510
increased leukocyte cell number J:53510
increased monocyte cell number J:53510
increased neutrophil cell number J:53510
pancreas inflammation J:53510
small intestinal inflammation J:53510
small spleen J:53510
spleen hypoplasia J:53510
stomach inflammation J:53510
thymus hypoplasia J:53510
Smad3tm1Cxd/Smad3tm1Cxd
(B6.129S6-Smad3tm1Cxd)
tubulointerstitial nephritis J:102084
Smad3tm1Cxd/Smad3tm1Cxd
(involves: 129S6/SvEvTac)
abnormal leukocyte physiology J:59673
decreased B cell apoptosis J:140567
osteoarthritis J:68792
Smad3tm1Cxd/Smad3tm1Cxd
(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive T cell differentiation J:136955
Smad3tm1Par/Smad3tm1Par
(129-Smad3tm1Par/J)
abnormal circulating interleukin-6 level J:175290
abnormal cytokine secretion J:175290
decreased interleukin-6 secretion J:175290
increased inflammatory response J:106572
Smad3tm1Xfw/Smad3tm1Xfw
(involves: 129/Sv * C57BL/6)
abnormal B cell proliferation J:53948
abnormal cytokine secretion J:53948
abnormal T cell proliferation J:53948
immune system phenotype J:53948
Smad4tm1.1Gsu/Smad4tm1.1Gsu
Ptf1atm1.1(cre)Cvw/Ptf1a+
Tg(MtTGFA)Lmb/0

(involves: 129S1/Sv * 129X1/SvJ * CD-1)
chronic pancreas inflammation J:229184
Smad4tm2.1Cxd/Smad4tm2.1Cxd
Tg(Foxn1-cre)8Ghr/0

(B6.Cg-Smad4tm2.1Cxd Tg(Foxn1-cre)8Ghr)
abnormal thymus physiology J:138837
small thymus J:138837
Smad4tm2.1Cxd/Smad4tm2.1Cxd
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

(involves: 129S6/SvEvTac * C57BL/6J * CD-1)
decreased osteoclast cell number J:211171
Smad7Gt(YHC053)Byg/Smad7Gt(YHC053)Byg
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal thymus morphology J:212881
thymus hypoplasia J:212881
Smad7tm1.1Ink/Smad7tm1.1Ink
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal T-helper 1 cell differentiation J:184670
decreased activated T cell number J:184670
decreased interferon-gamma secretion J:184670
decreased interleukin-9 secretion J:184670
decreased susceptibility to experimental autoimmune encephalomyelitis J:184670
decreased T cell proliferation J:184670
immune system phenotype J:184670
Smad7tm1Rheu/Smad7tm1Rheu
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal class switch recombination J:120714
decreased B cell proliferation J:120714
increased B cell apoptosis J:120714
Smad9tm3Jfm/Smad9tm3Jfm
(involves: 129S4/SvJaeSor)
lung inflammation J:150213
Smap1tm1.1Sata/Smap1tm1.1Sata
(B6.Cg-Smap1tm1.1Sata)
abnormal myelopoiesis J:196385
abnormal neutrophil morphology J:196385
enlarged spleen J:196385
increased neutrophil cell number J:196385
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn
Tg(Lck-cre)1Cwi/0

(Not Specified)
abnormal T cell morphology J:144072
decreased double-negative T cell number J:144072
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn
Tg(Lck-cre)1Cwi/0
Tg(LCKprBCL2L1)12Sjk/0

(Not Specified)
abnormal T cell morphology J:144072
decreased double-positive T cell number J:144072
increased double-negative T cell number J:144072
increased thymocyte number J:144072
Smarca4tm1.2Pcn/Smarca4tm1Mag
Tg(Lck-cre)1Cwi/?

(involves: 129S/Sv * C57BL/6 * DBA/2)
abnormal T cell differentiation J:85191
absent CD8-positive, alpha-beta T cells J:85191
arrested T cell differentiation J:85191
decreased CD4-positive, alpha-beta T cell number J:85191
decreased double-negative T cell number J:85191
decreased double-positive T cell number J:85191
thymus hypoplasia J:85191
Smarca4tm1.2Pcn/Smarca4tm1Mag
Tg(Lck-cre)1Cwi/?
Tg(LCKprBCL2)36Sjk/?

(involves: 129S/Sv * C57BL/6 * DBA/2)
arrested T cell differentiation J:85191
Smarca4tm1.2Pcn/Smarca4tm1Tich
Tg(Lck-cre)1Cwi/0

(involves: 129)
abnormal T cell morphology J:144072
decreased double-negative T cell number J:144072
decreased thymocyte number J:144072
Smarca4tm1.2Pcn/Smarca4tm1Tich
Tg(Lck-cre)1Cwi/0
Tg(LCKprBCL2L1)12Sjk/0

(involves: 129)
abnormal T cell morphology J:144072
decreased double-positive T cell number J:144072
increased double-negative T cell number J:144072
increased thymocyte number J:144072
Smarca4tm1Tich/Smarca4+
(involves: 129)
immune system phenotype J:144072
Smarca4tm1Tich/Smarca4+
Tg(Lck-cre)1Cwi/0

(involves: 129)
decreased double-negative T cell number J:144072
decreased double-positive T cell number J:144072
decreased single-positive T cell number J:144072
decreased thymocyte number J:144072
Smarcad1tm1Gos/Smarcad1tm1Gos
(129S2/SvPas-Smarcad1tm1Gos)
immune system phenotype J:56661
Smarcal1tm1.1Cfbo/Smarcal1tm1.1Cfbo
(either: B6.129-Smarcal1tm1.1Cfbo or (involves: 129 * C57BL/6))
decreased B cell number J:183899
Smarcb1tm1Sho/Smarcb1tm3Sho
Tg(Mx1-cre)1Cgn/?

(involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * CBA)
abnormal lymph node morphology J:80224
abnormal spleen morphology J:80224
enlarged lymph nodes J:80224
enlarged spleen J:80224
increased eosinophil cell number J:80224
Smarcc1tm2.1Rhs/Smarcc1tm2.1Rhs
Tg(Mx1-cre)1Cgn/0

(involves: BALB/c * C57BL/6 * CBA)
abnormal immature B cell morphology J:184060
abnormal immunoglobulin heavy chain V(D)J recombination J:184060
abnormal pre-B cell morphology J:184060
abnormal pro-B cell morphology J:184060
arrested B cell differentiation J:184060
decreased B cell number J:184060
decreased B cell proliferation J:184060
decreased early pro-B cell number J:184060
decreased follicular B cell number J:184060
decreased late pro-B cell number J:184060
decreased pro-B cell number J:184060
increased B cell apoptosis J:184060
Smarce1tm1Tich/Smarce1tm2.1Tich
Gt(ROSA)26Sortm3(CAG-flpo/ERT2)Alj/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
immune system phenotype J:194195
Smc3tm1a(EUCOMM)Wtsi/Smc3+
(involves: C57BL/6N)
increased T cell number J:200082
Smc5tm1b(KOMP)Wtsi/Smc5+
(C57BL/6N-Smc5tm1b(KOMP)Wtsi/Ics)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
Smc6tm1.1Arln/Smc6tm1.1Arln
(involves: 129P2/OlaHsd * C57BL/6 * FVB)
decreased IgG2b level J:220422
increased leukocyte cell number J:220422
Smcr8em1Btlr/Smcr8em1Btlr
(C57BL/6J-Smcr8em1Btlr)
enlarged lymph nodes J:268243
enlarged spleen J:268243
increased CD4-positive, alpha-beta T cell number J:268243
increased CD8-positive, alpha-beta T cell number J:268243
increased circulating interleukin-12b level J:268243
increased interleukin-6 secretion J:268243
increased susceptibility to induced colitis J:268243
increased tumor necrosis factor secretion J:268243
Smcr8em1Btlr/Smcr8em1Btlr
Tlr3tm1Flv/Tlr3tm1Flv
Tlr7tm1Aki/Tlr7tm1Aki
Tlr9tm1Aki/Tlr9tm1Aki

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6J)
immune system phenotype J:268243
Smcr8em2Btlr/Smcr8em2Btlr
(C57BL/6J-Smcr8em2Btlr)
enlarged lymph nodes J:268243
enlarged spleen J:268243
increased CD4-positive, alpha-beta T cell number J:268243
increased CD8-positive, alpha-beta T cell number J:268243
increased circulating interleukin-12b level J:268243
increased interleukin-6 secretion J:268243
increased susceptibility to induced colitis J:268243
increased tumor necrosis factor secretion J:268243
Smcr8m1Btlr/Smcr8+
(C57BL/6J-Smcr8m1Btlr)
increased susceptibility to induced colitis J:268243
Smcr8m1Btlr/Smcr8m1Btlr
(C57BL/6J-Smcr8m1Btlr)
increased susceptibility to induced colitis J:268243
increased tumor necrosis factor secretion J:268243
Smcr8m2Btlr/Smcr8m2Btlr
(C57BL/6J-Smcr8m2Btlr)
increased susceptibility to induced colitis J:268243
increased tumor necrosis factor secretion J:268243
Smcr8m3Btlr/Smcr8m3Btlr
(C57BL/6J-Smcr8m3Btlr)
increased susceptibility to induced colitis J:268243
increased tumor necrosis factor secretion J:268243
Smg1Gt(AG0297)Wtsi/Smg1+
(involves: 129P2/OlaHsd * C57BL/6)
chronic inflammation J:193626
decreased circulating interleukin-1 beta level J:193626
enlarged spleen J:193626
increased circulating interleukin-6 level J:193626
Smg6em1(IMPC)Mbp/Smg6+
(C57BL/6NCrl-Smg6em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Smg9tm1b(EUCOMM)Wtsi/Smg9tm1b(EUCOMM)Wtsi
(C57BL/6N-Smg9tm1b(EUCOMM)Wtsi/Wtsi)
absent connection between subcutaneous lymph vessels and lymph sac J:239583
blood in lymph vessels J:239583
Smim3tm1Anjm/Smim3+
Cd74tm1Anjm/Cd74+
Lmo2tm2(cre)Thr/Lmo2+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal mast cell morphology J:155870
decreased granulocyte number J:155870
decreased monocyte cell number J:155870
Smim23em1(IMPC)Mbp/Smim23em1(IMPC)Mbp
(C57BL/6N-Smim23em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Smoc1tm1b(EUCOMM)Wtsi/Smoc1+
(C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased large unstained cell number J:211773
increased neutrophil cell number J:211773
Smoc1tm1b(EUCOMM)Wtsi/Smoc1tm1b(EUCOMM)Wtsi
(C57BL/6N-Smoc1tm1b(EUCOMM)Wtsi/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Smpd1tm1Esc/Smpd1+
(involves: 129S1/Sv * C57BL/6J)
abnormal immune system cell morphology J:70489
Smpd1tm1Esc/Smpd1tm1Esc
(involves: 129S1/Sv * C57BL/6J)
abnormal granulocyte physiology J:81982
immune system phenotype J:44401
increased macrophage derived foam cell number J:81982
increased susceptibility to bacterial infection J:81982
Smpd1tm1Wst/Smpd1tm1Wst
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:26748
hepatosplenomegaly J:26748
increased macrophage derived foam cell number J:26748
Smpdl3btm1a(EUCOMM)Wtsi/Smpdl3btm1a(EUCOMM)Wtsi
(C57BL/6-Smpdl3btm1a(EUCOMM)Wtsi)
abnormal chemokine secretion J:224870
abnormal circulating chemokine level J:224870
abnormal macrophage morphology J:224870
increased circulating interleukin-6 level J:224870
increased circulating interleukin-12b level J:224870
increased circulating tumor necrosis factor level J:224870
increased neutrophil cell number J:224870
increased susceptibility to endotoxin shock J:224870
Smstm1a(EUCOMM)Wtsi/Y
(involves: C57BL/6 * C57BL/6N)
increased NK cell number J:213427
increased NK T cell number J:213427
Smtntm1Gve/Smtntm1Gve
(involves: 129/Sv * C57BL/6)
intestinal inflammation J:104648
sepsis J:104648
Smurf2Gt(RRA098)Byg/Smurf2Gt(RRA098)Byg
(involves: 129P2/OlaHsd * C57BL/6)
enlarged spleen J:189320
Snai2tm1Look/Snai2tm1Look
(involves: 129X1/SvJ * C57BL/6)
blepharitis J:80652
immune system phenotype J:80652
Snai2tm2Grid/Snai2+
Snai3tm1.2Jhws/Snai3tm1.2Jhws

(involves: 129/Sv * 129S1/Sv * C57BL/6)
abnormal thymus cortex morphology J:204710
abnormal thymus medulla morphology J:204710
decreased B cell number J:204710
disorganized spleen B cell follicle J:204710
Snai2tm2Grid/Snai2tm2Grid
(involves: 129S1/Sv)
abnormal T cell differentiation J:78323
blepharitis J:48521
conjunctivitis J:48521
decreased leukocyte cell number J:78323
small thymus J:78323
Snai2tm2Grid/Snai2tm2Grid
Snai3tm1.2Jhws/Snai3+

(involves: 129/Sv * 129S1/Sv * C57BL/6)
abnormal thymus cortex morphology J:204710
abnormal thymus medulla morphology J:204710
decreased B cell number J:204710
disorganized spleen B cell follicle J:204710
increased macrophage cell number J:204710
increased neutrophil cell number J:204710
Snai2tm2Grid/Snai2tm2Grid
Snai3tm1.2Jhws/Snai3tm1.2Jhws

(involves: 129/Sv * 129S1/Sv * C57BL/6)
abnormal thymus cortex morphology J:204710
abnormal thymus involution J:204710
abnormal thymus medulla morphology J:204710
decreased B cell number J:204710
decreased double-positive T cell number J:204710
disorganized spleen B cell follicle J:204710
increased macrophage cell number J:204710
increased neutrophil cell number J:204710
increased single-positive T cell number J:204710
small spleen J:204710
small thymus J:204710
thymus fibrosis J:204710
Snai3tm1.1Jhws/Snai3tm1.1Jhws
Tg(Lck-cre)548Jxm/0

(involves: 129/Sv * C57BL/6 * CBA)
immune system phenotype J:204710
Sncaem1(IMPC)H/Sncaem1(IMPC)H
(C57BL/6NTac-Sncaem1(IMPC)H/H)
increased spleen weight J:211773
Sncatm1Rosl/Sncatm1Rosl
(involves: 129X1/SvJ)
decreased susceptibility to bacterial infection J:138194
Sncatm1Rosl/Sncatm1Rosl
Tg(Prnp-SNCA)7Vle/Tg(Prnp-SNCA)7Vle

(involves: 129X1/SvJ * C3H * C57BL/6)
abnormal response to infection J:138194
Sncatm1Rosl/Sncatm1Rosl
Tg(Prnp-SNCA*A53T)83Vle/Tg(Prnp-SNCA*A53T)83Vle

(involves: 129X1/SvJ * C3H * C57BL/6)
increased susceptibility to bacterial infection J:138194
Snd1em1(IMPC)Tcp/Snd1+
(C57BL/6NCrl-Snd1em1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
decreased spleen weight J:211773
increased neutrophil cell number J:211773
small thymus J:211773
Snd1tm1.2Elws/Snd1tm1.2Elws
(involves: C57BL/6)
immune system phenotype J:324590
Snhg15tm1Nju/Snhg15tm1Nju
(involves: C57BL/6J)
immune system phenotype J:291983
Snord50a/Snord50btm1.1Soen/Snord50a/Snord50btm1.1Soen
(B6.129P2-Snord50a/Snord50btm1.1Soen)
enlarged lymph nodes J:206419
enlarged spleen J:206419
Snord50a/Snord50btm1.1Soen/Snord50a/Snord50btm1.1Soen
(B6.129P2-Snord50a/Snord50btm1.1Soen)
enlarged lymph nodes J:206419
enlarged spleen J:206419
Snrktm1.1Hxu/Snrktm1.1Hxu
Tg(Adipoq-cre)1Evdr/0

(B6.Cg-Snrktm1.1Hxu Tg(Adipoq-cre)1Evdr)
abnormal circulating chemokine level J:257980
brown adipose tissue inflammation J:257980
increased circulating interleukin-6 level J:257980
increased circulating tumor necrosis factor level J:257980
white adipose tissue inflammation J:257980
Snrnp40em1Btlr/Snrnp40swp
(C57BL/6J-Snrnp40em1Btlr/Snrnp40swp)
abnormal CD4-positive, alpha-beta T cell physiology J:282417
abnormal CD8-positive, alpha-beta T cell physiology J:282417
abnormal thymus development J:282417
decreased B cell number J:282417
decreased CD4-positive, alpha-beta T cell number J:282417
decreased CD8-positive, alpha-beta T cell number J:282417
decreased DN1 thymic pro-T cell number J:282417
decreased DN4 thymocyte number J:282417
decreased lymphocyte cell number J:282417
decreased monocyte cell number J:282417
decreased NK cell number J:282417
decreased T cell number J:282417
decreased T cell proliferation J:282417
immune system phenotype J:282417
impaired natural killer cell mediated cytotoxicity J:282417
increased central memory CD8 positive, alpha-beta T cell number J:282417
increased circulating interferon-beta level J:282417
increased circulating interferon-gamma level J:282417
increased circulating interleukin-6 level J:282417
increased circulating interleukin-12 level J:282417
increased circulating interleukin-17 level J:282417
increased circulating tumor necrosis factor level J:282417
increased effector memory CD8-positive, alpha-beta T cell number J:282417
increased susceptibility to viral infection J:282417
increased susceptibility to viral infection induced morbidity/mortality J:282417
small thymus J:282417
thymus hypoplasia J:282417
Snrnp200tm1b(KOMP)Mbp/Snrnp200+
(C57BL/6N-Snrnp200tm1b(KOMP)Mbp/H)
increased monocyte cell number J:211773
Snx8tm1Hbsh/Snx8tm1Hbsh
(Not Specified)
abnormal chemokine secretion J:254306
abnormal circulating chemokine level J:254306
abnormal dendritic cell physiology J:254306
abnormal macrophage physiology J:254306
decreased circulating CXCL10 level J:254306
decreased circulating tumor necrosis factor level J:254306
decreased CXCL10 secretion J:254306
decreased macrophage cytokine production J:254306
immune system phenotype J:254306
increased susceptibility to bacterial infection J:254306
increased susceptibility to bacterial infection induced morbidity/mortality J:254306
Snx8tm2a(EUCOMM)Hmgu/Snx8tm2a(EUCOMM)Hmgu
(C57BL/6N-Snx8tm2a(EUCOMM)Hmgu/Wtsi)
increased leukocyte cell number J:211773
Snx10em1Ael/Snx10em1Ael
(involves: 129 * C57BL/6J * C57BL/6JOlaHsd)
abnormal osteoclast morphology J:289051
abnormal osteoclast physiology J:289051
decreased osteoclast cell number J:289051
osteomyelitis J:289051
Snx10em2Ael/Snx10em2Ael
(involves: 129 * C57BL/6J * C57BL/6JOlaHsd)
abnormal osteoclast morphology J:289051
abnormal osteoclast physiology J:289051
decreased osteoclast cell number J:289051
osteomyelitis J:289051
Snx10tm1a(EUCOMM)Raba/Snx10tm1a(EUCOMM)Raba
(involves: 129S4/SvJae * C57BL/6 * C57BL/6J)
abnormal osteoclast physiology J:224711
Snx13tm1b(EUCOMM)Hmgu/Snx13+
(C57BL/6N-Snx13tm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Snx15tm1.1(KOMP)Vlcg/Snx15tm1.1(KOMP)Vlcg
(C57BL/6N-Snx15tm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Snx20tm1Lex/Snx20tm1Lex
Tg(Prm-cre)58Og/0

(involves: 129S/SvEvBrd * 129S4/SvJae)
immune system phenotype J:131282
Snx27tm1Lslo/Snx27tm1Lslo
(involves: 129P2/OlaHsd)
small spleen J:171001
Soat1ald/Soat1ald
(AKR/O)
thymus hyperplasia J:12157
Soat1m1Anu/Soat1m1Anu
(C57BL/6NCrlAnu-Soat1m1Anu)
immune system phenotype J:104190
Soat1tm1Far/Soat1tm1Far
(involves: 129S4/SvJae * C57BL/6)
abnormal macrophage morphology J:37049
Socs1tm1.1Ayr/Socs1tm1.1Ayr
(involves: C57BL/6)
abnormal T cell physiology J:226678
decreased effector memory T-helper cell number J:226678
decreased susceptibility to experimental autoimmune encephalomyelitis J:226678
Socs1tm1Ayos/Socs1tm1Ayos
Foxp3tm4(YFP/icre)Ayr/Foxp3+

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
blepharitis J:167922
conjunctivitis J:167922
dermatitis J:167922
increased regulatory T cell number J:167922
Socs1tm1Ayos/Socs1tm1Ayos
Tg(Lck-cre)1Jtak/0

(involves: 129S4/SvJae * C57BL/6)
abnormal CD4-positive T cell differentiation J:132905
abnormal CD4-positive, alpha-beta T cell physiology J:132905
decreased susceptibility to experimental autoimmune encephalomyelitis J:132905
Socs1tm1Ayos/Socs1tm1Ayos
Tg(Tek-cre)1Ywa/0

(involves: 129S4/SvJae * C57BL/6 * SJL)
decreased CD4-positive, alpha-beta T cell number J:132905
increased CD8-positive, alpha-beta T cell number J:132905
Socs1tm1Jni/Socs1+
(Not Specified)
abnormal cytokine level J:91651
abnormal interleukin level J:91651
Socs1tm1Jni/Socs1tm1Jni
(Not Specified)
abnormal cytokine secretion J:57475
abnormal T cell differentiation J:57475
decreased B cell number J:57475
decreased thymocyte number J:57475
Socs1tm1Kish/Socs1tm1Kish
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal spleen morphology J:51685
abnormal spleen white pulp morphology J:51685
absent thymus corticomedullary boundary J:51685
decreased lymphocyte cell number J:51685
Socs1tm1Kish/Socs1tm1Kish
(B6.129P2-Socs1tm1Kish)
abnormal lymphocyte physiology J:69472
increased activated T cell number J:69472
increased NK T cell number J:69472
liver inflammation J:69472
thymus atrophy J:69472
Socs1tm1Kish/Socs1tm1Kish
Stat1tm1Rds/Stat1tm1Rds

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
immune system phenotype J:69472
increased activated T cell number J:69472
liver inflammation J:69472
thymus atrophy J:69472
Socs1tm1Kish/Socs1tm1Kish
Stat6tm1Aki/Stat6tm1Aki

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:69472
increased activated T cell number J:69472
liver inflammation J:69472
thymus atrophy J:69472
Socs1tm1Wehi/Socs1tm1Wehi
(involves: 129S1/Sv * C57BL/6)
abnormal follicular B cell morphology J:51281
abnormal inflammatory response J:57474
abnormal lymph node B cell domain morphology J:51281
abnormal macrophage physiology J:57474
abnormal mature B cell morphology J:51281
abnormal Peyer's patch morphology J:51281
abnormal spleen white pulp morphology J:57474
decreased B cell number J:51281
decreased eosinophil cell number J:51281
decreased leukocyte cell number J:57474
decreased lymphocyte cell number J:51281
decreased pre-B cell number J:51281
decreased susceptibility to Togaviridae infection induced morbidity/mortality J:57474
heart inflammation J:51281
increased inflammatory response J:72528
increased spleen red pulp amount J:51281
liver inflammation J:51281
pancreas inflammation J:51281
small thymus J:51281
thymus cortex atrophy J:57474, J:51281
Socs1tm1Wehi/Socs1tm3Wehi
Tg(Lck-cre)I57Jxm/0

(involves: 129P2/OlaHsd * C57BL/6 * ICR)
abnormal CD4-positive, alpha beta T cell morphology J:83009
abnormal CD8-positive, alpha beta T cell morphology J:83009
abnormal T cell activation J:83009
abnormal T cell differentiation J:83009
abnormal T cell subpopulation ratio J:83009
decreased B cell number J:83009
enlarged lymph nodes J:83009
enlarged thymus medulla J:83009
increased CD4-positive, alpha-beta T cell number J:83009
increased CD8-positive, alpha-beta T cell number J:83009
lymph node hyperplasia J:83009
thymus hyperplasia J:83009
Socs1tm2Wehi/Socs1tm2Wehi
(C57BL/6-Socs1tm2Wehi)
absent spleen germinal center J:72528
glomerulonephritis J:72528
increased incidence of corneal inflammation J:72528
increased inflammatory response J:72528
intestinal inflammation J:72528
liver inflammation J:72528
myocarditis J:72528
myositis J:72528
pancreas inflammation J:72528
salivary gland inflammation J:72528
skin inflammation J:72528
thymus atrophy J:72528
Socs1tm3.1Wehi/Socs1tm3.1Wehi
(C57BL/6-Socs1tm3.1Wehi)
abnormal inflammatory response J:83009
increased circulating interferon-gamma level J:83009
Socs2em1(IMPC)H/Socs2em1(IMPC)H
(C57BL/6NTac-Socs2em1(IMPC)H/H)
increased spleen weight J:211773
Socs2tm1Wehi/Socs2tm1Wehi
(involves: C57BL/6 * C57BL/6J)
abnormal circulating cytokine level J:186227
abnormal macrophage physiology J:186227
increased circulating interferon-gamma level J:186227
increased circulating interleukin-1 beta level J:186227
increased interferon-gamma secretion J:186227
increased interleukin-1 beta secretion J:186227
increased tumor necrosis factor secretion J:186227
liver inflammation J:186227
Socs3tm1Ayos/Socs3tm1Ayos
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * C57BL/6)
decreased susceptibility to endotoxin shock J:92040
Socs3tm1Jni/Socs3+
(involves: 129P2/OlaHsd)
increased interleukin-2 secretion J:128797
Socs3tm1Robb/Socs3tm1Robb
(involves: C57BL/6)
enlarged spleen J:145513
increased neutrophil cell number J:145513
increased susceptibility to induced arthritis J:145513
Socs3tm1Wsa/Socs3tm2Wsa
Lyz2tm1(cre)Ifo/?

(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:83645
Socs3tm1Wsa/Socs3tm2Wsa
Tg(Vav1-cre)1Awr/0

(involves: C57BL/6)
abnormal granulocyte differentiation J:89785
abnormal myelopoiesis J:89785
enlarged spleen J:89785
increased inflammatory response J:89785
increased neutrophil cell number J:89785
liver inflammation J:89785
lung inflammation J:89785
peritoneal inflammation J:89785
Socs4m1Nch/Socs4m1Nch
(C.C3Fe-Socs4m1Nch)
abnormal chemokine secretion J:241977
abnormal T cell activation J:241977
decreased T cell number J:241977
immune system phenotype J:241977
increased interferon-gamma secretion J:241977
increased interleukin-1 secretion J:241977
increased interleukin-4 secretion J:241977
increased interleukin-5 secretion J:241977
increased interleukin-6 secretion J:241977
increased interleukin-12b secretion J:241977
increased interleukin-13 secretion J:241977
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:241977
increased T cell number J:241977
Socs4m1Nch/Socs4m1Nch
(C3H/He-Socs4m1Nch)
immune system phenotype J:241977
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:241977
Socs4m1Nch/Socs4m1Nch
(C6.C3Fe-Socs4m1Nch)
immune system phenotype J:241977
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:241977
Socs6tm1Dlk/Socs6tm1Dlk
(involves: C57BL/6)
immune system phenotype J:77039
Sod1m1H/Sod1m1H
(involves: C3H/HeH * C57BL/6J)
liver inflammation J:219360
microgliosis J:219360
Sod1tm1Leb/Sod1tm1Leb
(involves: 129S7/SvEvBrd * C57BL/6)
blepharitis J:219024
increased circulating interleukin-6 level J:219024
increased circulating tumor necrosis factor level J:219024
increased interleukin-6 secretion J:219024
increased tumor necrosis factor secretion J:219024
Meibomian gland inflammation J:219024
Sod2tm1Leb/Sod2tm1Leb
(B6.129S7-Sod2tm1Leb/J)
impaired myelopoiesis J:36148
Sod3tm1Mrkl/Sod3tm1Mrkl
(D1.129P2-Sod3tm1Mrkl)
arthritis J:106273
increased susceptibility to induced arthritis J:106273
increased tumor necrosis factor secretion J:106273
Sod3tm1Svp/Sod3tm1Svp
(involves: 129S6/SvEvTac * C57BL/6NTac)
decreased susceptibility to endotoxin shock J:285340
Sorbs1tm1Krc/Sorbs1tm1Krc
(B6.129-Sorbs1tm1Krc)
decreased leukocyte cell number J:121762
decreased lymphocyte cell number J:121762
decreased monocyte cell number J:121762
Sort1tm1Camo/Sort1tm1Camo
(B6.129X1-Sort1tm1Camo)
abnormal tumor necrosis factor level J:157549
Sos1tm1.1Les/Sos1tm1.1Les
Tg(Lck-cre)1Cwi/0

(involves: 129 * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:174536
decreased CD8-positive, alpha-beta T cell number J:174536
decreased DN4 thymocyte number J:174536
decreased double-negative T cell number J:174536
decreased double-positive T cell number J:174536
decreased gamma-delta T cell number J:174536
decreased T cell proliferation J:174536
decreased thymocyte number J:174536
Sos1tm1.2Rak/Sos1+
(involves: 129S/Sv * C57BL/6 * FVB/N * SJL)
enlarged spleen J:171873
increased leukocyte cell number J:171873
increased neutrophil cell number J:171873
increased spleen red pulp amount J:171873
Sostdc1tm1Snd/Sostdc1tm1Snd
(involves: C57BL/6)
decreased osteoclast cell number J:216098
Sox2tm3(TK)Hoch/Sox2+
(involves: 129S4/SvJae * C57BL/6)
stomach inflammation J:177655
tongue inflammation J:177655
Sox4Igt4/Del(13)36H
(involves: 101/H * C3H/HeH * C57BL/6)
thymus hypoplasia J:141688
Sox4tm1Cle/Sox4tm1Cle
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:32741
absent pre-B cells J:32741
decreased pro-B cell number J:32741
Sox4tm2Cle/Sox4tm2Cle
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:32741
absent pre-B cells J:32741
decreased pro-B cell number J:32741
Sox9em1(cre/ERT2)Smoc/Sox9+
Tnfsf18em1Pwan/Tnfsf18em1Pwan

(involves: C57BL/6J)
abnormal T cell activation J:346395
decreased CD8-positive, alpha-beta T cell number J:346395
decreased inflammatory response J:346395
Sox11tm1Weg/Sox11tm1Weg
(involves: 129S1/Sv * 129X1/SvJ)
absent spleen J:92251
Sox11tm2.2Weg/Sox11+
Sox4tm1.1Vlf/Sox4+

(involves: 129 * C57BL/6 * FVB/N)
small spleen J:175338
Sox11tm2.2Weg/Sox11+
Sox12tm2.1Weg/Sox12tm2.1Weg
Sox4tm1.1Vlf/Sox4+

(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6)
small spleen J:175338
Sox11tm2.2Weg/Sox11tm2.2Weg
(involves: 129 * C57BL/6)
absent spleen J:175338
Sox13tm1Jskg/Sox13+
(involves: C57BL/6)
decreased gamma-delta T cell number J:117301
Sox13tm1Jskg/Sox13tm1Jskg
(involves: C57BL/6)
decreased gamma-delta T cell number J:117301
increased T cell proliferation J:117301
Sox14em1(IMPC)Ccpcz/Sox14+
(C57BL/6N-Sox14em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Sox14em1(IMPC)Ccpcz/Sox14em1(IMPC)Ccpcz
(C57BL/6N-Sox14em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
Sox17tm1Sjm/Sox17tm2Sjm
Tg(Mx1-cre)1Cgn/0

(involves: 129/Sv * C3H * C57BL/6 * C57BL/Ka * CBA)
decreased leukocyte cell number J:123050
spleen hypoplasia J:123050
thymus hypoplasia J:123050
Sox17tm1Ysk/Sox17+
(involves: 129S1/Sv * C57BL/6)
liver inflammation J:194071
Sox17tm1Ysk/Sox17+
(B6.129S1-Sox17tm1Ysk)
gallbladder inflammation J:241569
liver inflammation J:194071
Sox17tm2Sjm/Sox17+
Tg(Pdx1-cre)6Tuv/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
liver inflammation J:241569
Sox18Ra-Op/Sox18Ra-Op
(B6D2-Sox18Ra-Op/J)
abnormal lymphatic vessel morphology J:143564
Sox18tm1Koop/Sox18tm1Koop
(B6.129-Sox18tm1Koop)
abnormal lymphatic vessel morphology J:143564
Sox21em1(IMPC)Mbp/Sox21em1(IMPC)Mbp
(C57BL/6NCrl-Sox21em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Sp3tm1Sus/Sp3tm1Sus
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:84837
decreased CD4-positive, alpha-beta T cell number J:84837
small thymus J:84837
Sp4tm1Sus/Sp4tm1Sus
(involves: 129P2/OlaHsd * C57BL/6)
spleen hypoplasia J:77894
thymus hypoplasia J:77894
Sp110em1Vnce/Sp110em1Vnce
(C57BL/6J-Sp110em1Vnce)
immune system phenotype J:313901
Sp140em1Vnce/Sp140em1Vnce
(C57BL/6J-Sp140em1Vnce)
increased susceptibility to bacterial infection J:313901
increased susceptibility to bacterial infection induced morbidity/mortality J:313901
Spag11aem1(IMPC)Mbp/Spag11aem1(IMPC)Mbp
(C57BL/6NCrl-Spag11aem1(IMPC)Mbp/Mmucd)
increased monocyte cell number J:211773
Sparctm1Hwe/Sparctm1Hwe
(involves: 129S/SvEv * C57BL/6J)
abnormal osteoclast morphology J:61480
decreased osteoclast cell number J:61480
eye inflammation J:52120
vitreous body inflammation J:52120
Spata2tm1(KOMP)Vlcg/Spata2tm1(KOMP)Vlcg
(C57BL/6-Spata2tm1(KOMP)Vlcg)
increased inflammatory response J:244164
Spata2tm1.1(KOMP)Vlcg/Spata2tm1.1(KOMP)Vlcg
(C57BL/6N-Spata2tm1.1(KOMP)Vlcg/Ucd)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Spata24tm1b(EUCOMM)Wtsi/Spata24tm1b(EUCOMM)Wtsi
(C57BL/6N-Spata24tm1b(EUCOMM)Wtsi/BayMmucd)
decreased neutrophil cell number J:211773
Spata31f3em1(IMPC)Ccpcz/Spata31f3em1(IMPC)Ccpcz
(C57BL/6NCrl-Spata31f3em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged thymus J:211773
increased CD8-positive, alpha-beta T cell number J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
spcy/spcy
(C57BL/6J-spcy)
abnormal innate immunity J:94077
Spdeftm1Shiv/Spdeftm1Shiv
(involves: 129S4/SvJae)
small intestinal inflammation J:166876
stomach inflammation J:166876
Spdye4btm3b(EUCOMM)Wtsi/Spdye4btm3b(EUCOMM)Wtsi
(C57BL/6N-Spdye4btm3b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Trmutm1Tomik/Trmutm1Tomik

(involves: C57BL/6 * DBA)
abnormal inflammatory response J:235644
Spef2bgh/Spef2bgh
(involves: 129S6/SvEvTac * C57BL/6J * C57BL/10J)
sinus inflammation J:176695
Spegtm1b(KOMP)Wtsi/Speg+
(C57BL/6N-Spegtm1b(KOMP)Wtsi/Nju)
increased basophil cell number J:211773
Spentm1Hon/Spentm1Hon
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal B cell differentiation J:82332
Spg11em1(IMPC)J/Spg11em1(IMPC)J
(C57BL/6NJ-Spg11em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Sphk1em1(IMPC)Mbp/Sphk1em1(IMPC)Mbp
(C57BL/6N-Sphk1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Sphk1tm1.1Cgh/Sphk1tm2Cgh
Sphk2tm1.1Cgh/Sphk2tm1.1Cgh
Tg(Mx1-cre)1Cgn/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
abnormal immune serum protein physiology J:120783
abnormal NK cell differentiation J:154069
abnormal T cell differentiation J:120783
abnormal thymus cell ratio J:120783
decreased B cell number J:120783
decreased NK cell number J:154069
decreased T cell number J:120783
increased NK cell number J:154069
Sphk1tm1Npa/Sphk1tm1Npa
(BALB/c-Sphk1tm1Npa)
increased B cell number J:129314
Sphk1tm1Rlp/Sphk1tm1Rlp
(involves: 129S6/SvEvTac)
abnormal cytokine level J:133917
decreased susceptibility to endotoxin shock J:133917
enlarged mesenteric lymph nodes J:133917
Sphk2Gt(NPX039)Byg/Sphk2Gt(NPX039)Byg
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:102911
Sphk2tm1.1Stlp/Sphk2tm1.1Stlp
(involves: BALB/c)
abnormal CD4-positive, alpha-beta T cell physiology J:153014
Sphk2tm1Npa/Sphk2tm1Npa
(BALB/c-Sphk2tm1Npa)
abnormal B cell physiology J:129314
increased B cell number J:129314
Spi1tm1.1Dgt/Spi1tm1.1Dgt
(involves: 129S1/Sv * 129X1/SvJ)
abnormal spleen morphology J:90331
decreased B cell number J:90331
enlarged spleen J:90331
spleen hyperplasia J:90331
Spi1tm1.2Nutt/Spi1tm1.2Nutt
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal granulocyte differentiation J:98188
abnormal spleen morphology J:98188
decreased B cell number J:98188
increased granulocyte number J:98188
Spi1tm1.3Dgt/Spi1tm1.3Dgt
(involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6)
abnormal double-negative T cell morphology J:106040
abnormal T cell subpopulation ratio J:106040
arrested B cell differentiation J:106040
decreased B-1a cell number J:106040
decreased granulocyte number J:106040
decreased mature B cell number J:106040
decreased pre-B cell number J:106040
decreased pro-B cell number J:106040
decreased T cell number J:106040
decreased thymocyte number J:106040
increased B-1 B cell number J:106040
increased B-1b cell number J:106040
increased IgM level J:106040
increased lymphocyte cell number J:106040
increased T cell number J:106040
small thymus J:106040
Spi1tm1.3Dgt/Spi1tm1.3Dgt
(involves: 129 * BALB/c * C57BL/6)
abnormal spleen morphology J:90331
decreased B cell number J:90331
enlarged spleen J:90331
increased neutrophil cell number J:90331
increased spleen weight J:90331
spleen hyperplasia J:90331
Spi1tm1Kast/Spi1tm1Kast
(B6.129S2-Spi1tm1Kast)
absent B cells J:90543
failure of myelopoiesis J:90543
Spi1tm1Ram/Spi1tm1Ram
(involves: 129S2/SvPas)
decreased macrophage cell number J:101493
Spi1tm1Ram/Spi1tm1Ram
(involves: 129S2/SvPas * C57BL/6)
abnormal B cell number J:36473
abnormal macrophage differentiation J:36473
abnormal microglial cell morphology J:116087
abnormal neutrophil differentiation J:36473
abnormal T cell differentiation J:36473
abnormal T cell number J:36473
absent mature B cells J:36473
decreased CD4-positive, alpha-beta T cell number J:36473
decreased CD8-positive, alpha-beta T cell number J:36473
decreased double-positive T cell number J:36473
decreased macrophage cell number J:36473
decreased neutrophil cell number J:36473
decreased spleen red pulp amount J:36473
decreased thymocyte number J:36473
sepsis J:36473
Spi1tm1Rpd/Spi1tm1Rpd
(involves: 129/Sv * C57BL/6 * Black Swiss)
abnormal myelopoiesis J:123079
arrested B cell differentiation J:123079
enlarged spleen J:123079
impaired myelopoiesis J:123079
Spi1tm1Sing/Spi1+
Spibtm1Mcs/Spib+

(involves: 129S/SvEv * 129X1/SvJ)
abnormal spleen germinal center morphology J:88257
decreased B cell proliferation J:88257
Spi1tm1Sing/Spi1+
Spibtm1Mcs/Spibtm1Mcs

(involves: 129S/SvEv * 129X1/SvJ)
abnormal B cell differentiation J:88257
abnormal immature B cell morphology J:88257
absent spleen germinal center J:88257
decreased B cell number J:88257
decreased B cell proliferation J:88257
immune system phenotype J:88257
increased B cell apoptosis J:88257
Spi1tm1Sing/Spi1tm1Sing
(involves: 129S/SvEv)
abnormal B cell differentiation J:20348
abnormal granulocyte morphology J:20348
abnormal leukopoiesis J:20348
abnormal monocyte morphology J:20348
abnormal T cell differentiation J:20348
Spi1tm3Dgt/Spi1tm3Dgt
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased B cell number J:131217
decreased double-negative T cell number J:131217
increased double-negative T cell number J:131217
increased granulocyte number J:131217
Spibtm1Ksho/Spibtm1Ksho
(involves: C57BL/6J)
abnormal Peyer's patch morphology J:187649
increased susceptibility to bacterial infection J:187649
Spibtm1Mcs/Spibtm1Mcs
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal immature B cell morphology J:88257
decreased B cell proliferation J:88257
Spibtm1Mcs/Spibtm1Mcs
(involves: 129S1/Sv * 129X1/SvJ)
abnormal humoral immune response J:45245
abnormal spleen B cell follicle morphology J:45245
abnormal spleen germinal center morphology J:45245
abnormal spleen white pulp morphology J:45245
decreased B cell proliferation J:45245
decreased IgG1 level J:45245
decreased IgG2a level J:45245
decreased IgG2b level J:45245
increased B cell apoptosis J:45245
increased IgM level J:45245
Spictm1.1Kmm/Spictm1.1Kmm
(involves: 129S6/SvEvTac * C57BL/6)
abnormal macrophage morphology J:143900
impaired macrophage phagocytosis J:143900
increased spleen iron level J:143900
increased spleen weight J:143900
Spictm1Kmm/Spictm1Kmm
(involves: 129S6/SvEvTac * C57BL/6)
abnormal macrophage morphology J:143900
impaired macrophage phagocytosis J:143900
increased spleen iron level J:143900
increased spleen weight J:143900
Spin4em1Jbn/Y
(involves: C57BL/6J)
increased spleen weight J:347154
Spin4em2Jbn/Y
(involves: C57BL/6J)
increased spleen weight J:347154
Spink1tm1Kymm/Spink1tm1Kymm
(involves: C57BL/6NCrlj * CBA/JNCrlj)
small spleen J:104647
Spink2tm1.1(KOMP)Vlcg/Spink2tm1.1(KOMP)Vlcg
(C57BL/6N-Spink2tm1.1(KOMP)Vlcg/Ucd)
increased basophil cell number J:211773
Spink5m1Btlr/Spink5m1Btlr
(involves: C57BL/6J)
increased neutrophil cell number J:183755
Spink6em1(IMPC)Ccpcz/Spink6em1(IMPC)Ccpcz
(C57BL/6N-Spink6em1(IMPC)Ccpcz/Ccpcz)
decreased Ly6C-positive immature NK cell number J:211773
decreased macrophage cell number J:211773
increased Ly6C-positive mature NK cell number J:211773
increased monocyte cell number J:211773
Spink7em1Cya/Spink7em1Cya
(C57BL/6N-Spink7em1Cya/Cya)
increased interleukin-1 beta secretion J:310883
increased interleukin-6 secretion J:310883
increased susceptibility to induced colitis J:310883
Spink13em1(IMPC)Ccpcz/Spink13em1(IMPC)Ccpcz
(C57BL/6N-Spink13em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
Spink14tm1e(KOMP)Wtsi/Spink14tm1e(KOMP)Wtsi
(C57BL/6N-Spink14tm1e(KOMP)Wtsi/Wtsi)
decreased immature NK cell number J:211773
decreased macrophage cell number J:211773
decreased mature NK cell number J:211773
decreased NK cell number J:211773
increased anti-nuclear antigen antibody level J:211773
increased memory-marker NK cell number J:211773
Spint1tm2.1Hk/Spint1tm2.1Hk
Tg(Vil1-cre)997Gum/0

(involves: C57BL/6 * C57BL/6J * SJL)
increased susceptibility to induced colitis J:179937
Spir1BALB/cOlaHsd/Spir1BALB/cOlaHsd
(involves: BALB/cOlaHsd * CBA/CaOlaHsd)
decreased susceptibility to bacterial infection J:84089
Spir1BALB/cOlaHsd/Spir1CBA/CaOlaHsd
(involves: BALB/cOlaHsd * CBA/CaOlaHsd)
decreased susceptibility to bacterial infection J:84089
Spir1CBA/CaOlaHsd/Spir1CBA/CaOlaHsd
(involves: BALB/cOlaHsd * CBA/CaOlaHsd)
increased susceptibility to bacterial infection J:84089
Splq1L6/Splq1L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq1L6/Splq1M16i
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq2L6/Splq2L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq2L6/Splq2M16i
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq3L6/Splq3L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq4L6/Splq4L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq4L6/Splq4M16i
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq5L6/Splq5L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq5L6/Splq5M16i
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq6L6/Splq6L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq6L6/Splq6M16i
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq7L6/Splq7L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq8L6/Splq8L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq8L6/Splq8M16i
(involves: L6 * M16i)
decreased spleen weight J:87793
Splq9L6/Splq9L6
(involves: L6 * M16i)
decreased spleen weight J:87793
Splwt1LG/J/?
(involves: LG/J * SM/J)
increased spleen weight J:94605
Spm1C57BL/6/?
(involves: C57BL/6 * NZB)
abnormal immune system organ morphology J:59427
Spmip2tm1b(EUCOMM)Hmgu/Spmip2tm1b(EUCOMM)Hmgu
(C57BL/6N-Spmip2tm1b(EUCOMM)Hmgu/Bay)
abnormal spleen morphology J:211773
Spntm1Bam/Spntm1Bam
(involves: 129S4/SvJae * C57BL/6)
abnormal T cell physiology J:29272
increased T cell proliferation J:29272, J:88252
Spntm1Bam/Spntm1Bam
(B6;129S4-Spntm1Bam/J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:86932
immune system phenotype J:66401
Spns2tm1.1Nmoc/Spns2tm1.1Nmoc
Tg(Tek-cre)1Ywa/0

(involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * SJL)
abnormal B cell physiology J:184558
abnormal effector T cell morphology J:184558
abnormal T cell physiology J:184558
decreased CD4-positive, alpha-beta T cell number J:184558
decreased CD8-positive, alpha-beta T cell number J:184558
decreased mature B cell number J:184558
increased CD4-positive, alpha-beta T cell number J:184558
increased CD8-positive, alpha-beta T cell number J:184558
Spns2tm1.2Nmoc/Spns2tm1.2Nmoc
(involves: C57BL/6NCrlj * CBA/JNCrlj)
abnormal B cell physiology J:184558
abnormal T cell physiology J:184558
decreased B-1 B cell number J:184558
decreased CD4-positive, alpha-beta T cell number J:184558
decreased CD8-positive, alpha-beta T cell number J:184558
decreased follicular B cell number J:184558
decreased immature B cell number J:184558
decreased leukocyte cell number J:184558
decreased mature B cell number J:184558
decreased transitional stage T1 B cell number J:184558
increased CD4-positive, alpha-beta T cell number J:184558
increased CD8-positive, alpha-beta T cell number J:184558
increased single-positive T cell number J:184558
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
(B6JTyr;B6N-Spns2tm1a(KOMP)Wtsi/Wtsi)
decreased leukocyte cell number J:165965
Spns2tm1a(KOMP)Wtsi/Spns2tm1a(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
abnormal humoral immune response J:188933
decreased B cell number J:188933, J:213427
decreased B-1 B cell number J:188933
decreased CD4-positive, alpha-beta T cell number J:188933, J:213427
decreased CD8-positive, alpha-beta T cell number J:188933, J:213427
decreased follicular B cell number J:188933
decreased IgG1 level J:188933
decreased IgG level J:188933
decreased leukocyte cell number J:188933, J:213427
decreased mature B cell number J:213427
decreased T cell number J:213427
immune system phenotype J:188933
increased CD4-positive, alpha-beta T cell number J:188933
increased CD8-positive, alpha-beta T cell number J:188933
increased granulocyte number J:213427
increased incidence of corneal inflammation J:213427
increased monocyte cell number J:213427
increased NK cell number J:213427
increased NK T cell number J:213427
increased susceptibility to bacterial infection J:213427
Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
(involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6N)
decreased B cell number J:188933
decreased CD4-positive, alpha-beta T cell number J:188933
decreased CD8-positive, alpha-beta T cell number J:188933
increased CD4-positive, alpha-beta T cell number J:188933
increased CD8-positive, alpha-beta T cell number J:188933
Spns2tm1b(KOMP)Wtsi/Spns2tm1b(KOMP)Wtsi
(B6Brd;B6Dnk;B6N-Tyrc-Brd Spns2tm1b(KOMP)Wtsi/WtsiH)
decreased leukocyte cell number J:211773
Spns2tm1c(KOMP)Wtsi/Spns2tm1c(KOMP)Wtsi
(involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N)
immune system phenotype J:188933
Spns2tm1Tni/Spns2tm1Tni
(B6.Cg-Spns2tm1Tni)
abnormal leukocyte cell number J:225108
abnormal mature B cell number J:225108
abnormal thymus morphology J:225108
decreased leukocyte cell number J:225108
decreased lymphocyte cell number J:225108
decreased monocyte cell number J:225108
decreased single-positive T cell number J:225108
decreased thymocyte number J:225108
Spns3em1(IMPC)Tcp/Spns3em1(IMPC)Tcp
(C57BL/6NCrl-Spns3em1(IMPC)Tcp/Tcp)
increased eosinophil cell number J:211773
Spnw1DBA/2/Spnw1DBA/2
Spnw4DU6i/Spnw4DU6i

(involves: DBA/2 * DU6i)
increased spleen weight J:101006
Spo11tm1Mjn/Spo11tm1Mjn
(involves: 129X1/SvJ * C57BL/6)
immune system phenotype J:74754
Spo11tm2b(KOMP)Wtsi/Spo11tm2b(KOMP)Wtsi
(C57BL/6N-Spo11tm2b(KOMP)Wtsi/Bay)
abnormal spleen morphology J:211773
increased spleen weight J:211773
Spon2tm1Mjb/Spon2tm1Mjb
(involves: 129S6/SvEvTac * C57BL/6)
abnormal interleukin level J:87393
abnormal susceptibility to infection J:87393
abnormal tumor necrosis factor level J:87393
Spoptm1b(KOMP)Wtsi/Spop+
(C57BL/6N-Spoptm1b(KOMP)Wtsi/Tcp)
enlarged lymph nodes J:211773
small thymus J:211773
Spp1Ric-r/Spp1+
(AKR/J)
decreased susceptibility to bacterial infection J:5949
Spp1Ric-r/Spp1+
(A/J)
decreased susceptibility to bacterial infection J:5949
Spp1Ric-r/Spp1+
(BALB/cJ)
decreased susceptibility to bacterial infection J:5949
Spp1Ric-r/Spp1+
(C57BL/6J)
decreased susceptibility to bacterial infection J:5949
Spp1Ric-r/Spp1+
(C57L/J)
decreased susceptibility to bacterial infection J:5949
Spp1Ric-r/Spp1+
(SWR/J)
decreased susceptibility to bacterial infection J:5949
Spp1Ric-r/Spp1+
(C3H/Rv)
decreased susceptibility to bacterial infection induced morbidity/mortality J:7240
increased macrophage cell number J:7240
Spp1Ric-s/Spp1+
(A/HeJ)
increased susceptibility to bacterial infection J:5949
Spp1Ric-s/Spp1+
(C3H/HeJ)
increased susceptibility to bacterial infection J:5949
Spp1Ric-s/Spp1+
(C3H/HeN)
increased susceptibility to bacterial infection J:5949
Spp1Ric-s/Spp1+
(C3H/St)
increased susceptibility to bacterial infection J:5949
Spp1Ric-s/Spp1+
(CBA/J)
increased susceptibility to bacterial infection J:5949
Spp1Ric-s/Spp1+
(DBA/1J)
increased susceptibility to bacterial infection J:5949
Spp1Ric-s/Spp1+
(DBA/2J)
increased susceptibility to bacterial infection J:5949
Spp1Ric-s/Spp1+
(SJL/J)
increased susceptibility to bacterial infection J:5949
Spp1tm1.1Dhd/Spp1tm1.1Dhd
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage morphology J:237104
abnormal osteoclast physiology J:237104
decreased osteoclast cell number J:237104
Spp1tm1Blh/Spp1+
(BKSW.129S6-Spp1tm1Blh)
abnormal immune system physiology J:113585
Spp1tm1Blh/Spp1+
(involves: 129S6/SvEvTac * Black Swiss)
abnormal leukocyte migration J:86531
Spp1tm1Blh/Spp1tm1Blh
(involves: 129S6/SvEvTac * Black Swiss)
abnormal chemokine level J:127389
abnormal leukocyte migration J:86531
abnormal leukocyte physiology J:86531
abnormal macrophage chemotaxis J:140014
abnormal macrophage physiology J:127389
abnormal response to infection J:103013
abnormal susceptibility to infection J:140014
decreased circulating interleukin-6 level J:127389
decreased leukocyte cell number J:86531
decreased macrophage cell number J:127389
granulomatous inflammation J:140014
increased lymphocyte cell number J:103050
Spp1tm1Blh/Spp1tm1Blh
(B6.129S6-Spp1tm1Blh)
abnormal microglial cell morphology J:118432
decreased susceptibility to experimental autoimmune uveoretinitis J:116272
granulomatous inflammation J:116272
Spp1tm1Blh/Spp1tm1Blh
(involves: 129S6/SvEvTac * C57BL/6)
abnormal immune system physiology J:119298
decreased dendritic cell number J:119298
Spp1tm1Blh/Spp1tm1Blh
(BKSW.129S6-Spp1tm1Blh)
abnormal immune system physiology J:113585
impaired macrophage chemotaxis J:113585
Spp1tm1Rit/Spp1tm1Rit
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal inflammatory response J:60284
abnormal osteoclast physiology J:68872, J:56353
abnormal response to infection J:60284
decreased interferon-gamma secretion J:60284
decreased interleukin-12 secretion J:60284
decreased osteoclast cell number J:115395
decreased susceptibility to Herpesvirales infection J:60284
decreased susceptibility to type IV hypersensitivity reaction J:60284
increased interleukin-4 secretion J:60284
increased interleukin-10 secretion J:60284
increased osteoclast cell number J:56353, J:56535
Spp1tm1Rit/Spp1tm1Rit
(B6.129S7-Spp1tm1Rit)
decreased acute inflammation J:93915
decreased interferon-gamma secretion J:93915
decreased tumor necrosis factor secretion J:93915
Sppl2achompB/Sppl2achompB
(involves: C57BL/6)
abnormal class switch recombination J:194595
abnormal humoral immune response J:194595
decreased activation-induced B cell apoptosis J:194595
decreased B cell proliferation J:194595
decreased follicular B cell number J:194595
decreased IgG1 level J:194595
decreased IgG2b level J:194595
decreased IgG3 level J:194595
decreased IgM level J:194595
decreased marginal zone B cell number J:194595
decreased mature B cell number J:194595
decreased myeloid dendritic cell number J:194595
decreased plasmacytoid dendritic cell number J:194595
decreased transitional stage T2 B cell number J:194595
immune system phenotype J:194595
Sppl2am1Anu/Sppl2am1Anu
(involves: C57BL/6JAnu)
abnormal immunoglobulin level J:194663
abnormal mature B cell morphology J:194663
abnormal transitional stage B cell morphology J:194663
decreased IgG1 level J:194663
decreased IgM level J:194663
decreased marginal zone B cell number J:194663
decreased transitional stage T2 B cell number J:194663
decreased transitional stage T3 B cell number J:194663
Sppl2am1Anu/Sppl2am1Anu
Tg(Vav-BCL2)69Jad/?

(involves: C57BL/6JAnu)
abnormal T cell number J:194663
decreased CD4-positive, alpha-beta T cell number J:194663
decreased double-negative T cell number J:194663
increased mature B cell number J:194663
increased plasmacytoid dendritic cell number J:194663
Sppl2am1Btlr/Sppl2am1Btlr
(C57BL/6J-Sppl2am1Btlr)
decreased IgG level J:236687
decreased response to antigen J:236687
Sppl2am2Btlr/Sppl2am2Btlr
(C57BL/6J-Sppl2am2Btlr)
decreased IgG level J:236688
decreased IgM level J:236688
decreased response to antigen J:236688
Sppl2atm1Basc/Sppl2atm1Basc
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl)
abnormal B cell physiology J:194664
arrested B cell differentiation J:194664
decreased B cell number J:194664
decreased B-1 B cell number J:194664
decreased B-2 B cell number J:194664
decreased follicular B cell number J:194664
decreased IgA level J:194664
decreased IgG1 level J:194664
decreased IgG2a level J:194664
decreased IgG2b level J:194664
decreased IgG3 level J:194664
decreased IgM level J:194664
decreased marginal zone B cell number J:194664
decreased mature B cell number J:194664
decreased Peyer's patch number J:194664
decreased T cell number J:194664
decreased transitional stage T2 B cell number J:194664
small Peyer's patches J:194664
small spleen J:194664
Sppl2atm1Basc/Sppl2atm1Basc
Sppl2bGt(Ayu21-T160)Imeg/Sppl2bGt(Ayu21-T160)Imeg

(B6N.Cg-Sppl2atm1Basc Sppl2bGt(Ayu21-T160)Imeg)
abnormal mature B cell morphology J:213519
decreased B cell number J:213519
decreased immunoglobulin level J:213519
Sppl2atm1Dgen/Sppl2atm1Dgen
(B6.129P2-Sppl2atm1Dgen)
decreased B cell number J:194595
decreased B-1 B cell number J:194595
decreased follicular B cell number J:194595
decreased IgA level J:194595
decreased IgG1 level J:194595
decreased IgG2b level J:194595
decreased IgG3 level J:194595
decreased IgM level J:194595
decreased myeloid dendritic cell number J:194595
decreased transitional stage T2 B cell number J:194595
Sppl2bGt(Ayu21-T160)Imeg/Sppl2bGt(Ayu21-T160)Imeg
(B6N.Cg-Sppl2bGt(Ayu21-T160)Imeg)
immune system phenotype J:213519
Sppl3tm1Itl/Sppl3em1Pomz
Ncr1tm1.1(icre)Viv/Ncr1+

(involves: 129S/SvEv * C57BL/6 * C57BL/6J)
abnormal NK cell differentiation J:280182
decreased mature NK cell number J:280182
decreased NK cell number J:280182
increased immature NK cell number J:280182
Sppl3tm1Itl/Sppl3tm1Itl
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S/SvEv * C57BL/6 * C57BL/10 * CBA/Ca)
abnormal NK cell differentiation J:280182
decreased mature NK cell number J:280182
decreased NK cell number J:280182
immune system phenotype J:280182
impaired natural killer cell mediated cytotoxicity J:280182
increased immature NK cell number J:280182
Sppl3tm1Itl/Sppl3tm1Itl
Ncr1tm1.1(icre)Viv/Ncr1+

(involves: 129S/SvEv * C57BL/6)
abnormal NK cell differentiation J:280182
abnormal NK cell physiology J:280182
decreased mature NK cell number J:280182
decreased NK cell number J:280182
impaired natural killer cell mediated cytotoxicity J:280182
increased immature NK cell number J:280182
Sprem1(IMPC)H/Spr+
(C57BL/6N-Sprem1(IMPC)H/H)
increased neutrophil cell number J:211773
Spred1em1(IMPC)Ccpcz/Spred1em1(IMPC)Ccpcz
(C57BL/6N-Spred1em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased CD4-positive NK T cell number J:211773
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased effector memory T-helper cell number J:211773
increased memory-marker CD4-positive NK T cell number J:211773
increased neutrophil cell number J:211773
increased NK T cell number J:211773
increased spleen weight J:211773
Spred1tm1.1Ayos/Spred1tm1.1Ayos
(involves: 129 * C57BL/6 * SJL)
increased mast cell degranulation J:186742
increased mast cell number J:186742
Spred1tm1Hiin/Spred1tm1Hiin
(involves: C57BL/6)
abnormal cytokine secretion J:95263
abnormal eosinophil physiology J:95263
increased eosinophil cell number J:95263
Spred2em1(IMPC)Mbp/Spred2em1(IMPC)Mbp
(C57BL/6N-Spred2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Spred3em1(IMPC)Tcp/Spred3+
(C57BL/6NCrl-Spred3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Sprol1STS/A/?
(involves: B10.O20/Dem * O20/A)
increased lymphocyte cell number J:56029
Spryd4em1(IMPC)Ccpcz/Spryd4em1(IMPC)Ccpcz
(C57BL/6N-Spryd4em1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Spta1ihj/Spta1ihj
(involves: HRS/J * LAH)
abnormal spleen morphology J:105409
enlarged spleen J:105409
Spta1sph-2Bc/Spta1sph-2Bc
(involves: SELH)
abnormal spleen morphology J:7048
enlarged spleen J:7048
increased leukocyte cell number J:7048
Spta1sph-3J/Spta1sph-3J
(NOD.Cg-H2b Spta1sph-3J)
decreased spleen iron level J:157766
enlarged spleen J:157766
increased spleen weight J:157766
Spta1sph-4J/Spta1sph-4J
(C57BL/6J-Spta1sph-4J/Llp)
enlarged spleen J:157766
increased spleen weight J:157766
Spta1sph-Dem/Spta1sph-Dem
(CcS3/Dem-Spta1sph-Dem)
enlarged spleen J:66966
Spta1sph-ha/Spta1sph-ha
(involves: DBA/1J)
enlarged spleen J:30699, J:14946
Spta1sph-ha/Spta1sph-ha
(either: (B6.D1-Spta1sph-ha x WB.D1-Spta1sph-ha)F1 or (WB.D1-Spta1sph-ha x B6.D1-Spta1sph-ha)F1)
abnormal lymph node cell ratio J:1967
abnormal spleen morphology J:6695
abnormal splenic cell ratio J:1967
alveolitis J:12830
enlarged spleen J:6695
increased B cell number J:1967
increased B cell proliferation J:1967
increased CD4-positive, alpha-beta T cell number J:1967
increased CD8-positive, alpha-beta T cell number J:1967
increased IgA level J:12830
increased IgG level J:12830
increased leukocyte cell number J:12830
increased lymphocyte cell number J:12830, J:1967
increased monocyte cell number J:12830
increased neutrophil cell number J:12830
increased susceptibility to bacterial infection J:12830
increased T cell number J:1967
increased T cell proliferation J:1967
interstitial pneumonia J:12830
lymph node hyperplasia J:12830, J:1967
Spta1sph-ha/Spta1sph-ha
((WB.D1-Spta1sph-ha/Brk x B6.D1-Spta1sph-ha/Brk)F1)
enlarged spleen J:162532
Spta1sph/Spta1sph
(either: (B6.C3-Spta1sph x WB.C3-Spta1sph)F1 or (WB.C3-Spta1sph x B6.C3-Spta1sph)F1)
abnormal spleen morphology J:6695
decreased susceptibility to parasitic infection J:111131
enlarged spleen J:6695
Spta1sph/Spta1sph
((WB.C3-Spta1sph x B6.C3-Spta1sph)F1)
enlarged spleen J:162532, J:44313
glomerulonephritis J:44313
tubular nephritis J:44313
Sptan1em1(IMPC)Mbp/Sptan1+
(C57BL/6NCrl-Sptan1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Sptbja/Sptbja
(129/Sv-Sptbja)
enlarged spleen J:305
Sptbja/Sptbja
((WB.129-Sptbja/J x B6.129-Sptbja/J)F1)
enlarged spleen J:162532, J:44313
glomerulonephritis J:44313
increased spleen red pulp amount J:44313
tubular nephritis J:44313
Sptbm1Jus/Sptbm1Jus
(involves: 129S6/SvEvTac * C57BL/6)
enlarged spleen J:159750
Sptbn4qv/Sptbn4qv
(either: (involves: BALB/c) or (involves: C57BL/10))
eye inflammation J:167
Sptlc2tm1Yhir/Sptlc2tm1Yhir
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6NTac)
abnormal spleen morphology J:202954
abnormal thymus morphology J:202954
decreased lymphocyte cell number J:202954
decreased spleen weight J:202954
decreased thymus weight J:202954
increased neutrophil cell number J:202954
Sptlc2tm1Yhir/Sptlc2tm1Yhir
Tg(KRT5-cre)1Tak/0

(involves: C3H * C57BL/6)
abnormal dendritic epidermal T cell morphology J:202388
abnormal Langerhans cell morphology J:202388
abnormal Langerhans cell physiology J:202388
increased dendritic cell number J:202388
increased gamma-delta T cell number J:202388
increased T-helper 17 cell number J:202388
skin inflammation J:202388
Spw1SWR/J/Spw1SWR/J
Tg(CTSG-PML/RARA)135Ley/0

(involves: C3H/HeJ * C57BL/6J * SWR/J)
decreased spleen weight J:139159
Spw2SWR/J/?
Tg(CTSG-PML/RARA)135Ley/0

(involves: C3H/HeJ * C57BL/6J * SWR/J)
decreased spleen weight J:139159
Spw3SWR/J/Spw3SWR/J
Tg(CTSG-PML/RARA)135Ley/0

(involves: C3H/HeJ * C57BL/6J * SWR/J)
increased spleen weight J:139159
Spw4SWR/J/Spw4SWR/J
Tg(CTSG-PML/RARA)135Ley/0

(involves: C3H/HeJ * C57BL/6J * SWR/J)
decreased spleen weight J:139159
Spw5SWR/J/Spw5SWR/J
Tg(CTSG-PML/RARA)135Ley/0

(involves: C3H/HeJ * C57BL/6J * SWR/J)
decreased spleen weight J:139159
increased spleen weight J:139159
Spz1em1(IMPC)Mbp/Spz1em1(IMPC)Mbp
(C57BL/6N-Spz1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Sqstm1tm1.1Sral/Sqstm1+
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:173755
increased osteoclast cell number J:173755
Sqstm1tm1.1Sral/Sqstm1tm1.1Sral
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:173755
abnormal osteoclast morphology J:173755
increased osteoclast cell number J:173755
Sqstm1tm1Jjw/Sqstm1tm1Jjw
(involves: 129 * C57BL/6)
abnormal osteoclast differentiation J:141179
abnormal osteoclast physiology J:141179
Sqstm1tm1Jmos/Sqstm1tm1Jmos
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal osteoclast differentiation J:90010
decreased interleukin-6 secretion J:90010
decreased osteoclast cell number J:90010
Sqstm1tm1Keta/Sqstm1tm1Keta
(involves: 129 * C57BL/6N)
abnormal osteoclast differentiation J:264183
abnormal osteoclast physiology J:264183
Sra1tm1a(EUCOMM)Hmgu/Sra1tm1a(EUCOMM)Hmgu
(involves: C57BL/6J * C57BL/6N)
decreased circulating tumor necrosis factor level J:214131
Srctm1Sor/Srctm1Sor
(either: 129S7/SvEvBrd-Srctm1Sor or (involves: 129S7/SvEvBrd * C57BL/6J))
increased inflammatory response J:67040
periodontium inflammation J:67040
Srcr/Srcr+
(BALB/c-Srcr/Cui)
abnormal innate immunity J:83618
Srd5a2em1(IMPC)Mbp/Srd5a2em1(IMPC)Mbp
(C57BL/6N-Srd5a2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Srftm1Rmn/Srftm1Rmn
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129S6/SvEvTac * C57BL/6J * CBA/J)
athymia J:144862
Srftm2Nor/Srftm2Nor
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd)
abnormal mature B cell morphology J:124767
absent marginal zone B cells J:124767
decreased B cell number J:124767
decreased B-1 B cell number J:124767
Srftm2Nor/Srftm2Nor
Tg(Cd4-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2)
decreased CD4-positive, alpha-beta T cell number J:124767
decreased CD8-positive, alpha-beta T cell number J:124767
decreased T cell number J:124767
decreased thymocyte number J:124767
Srgntm1Mabr/Srgntm1Mabr
(involves: 129X1/SvJ)
abnormal mast cell morphology J:93338
decreased mast cell number J:93338
Sros1em1Caox/Sros1em1Caox
(involves: C57BL/6J)
abnormal circulating chemokine level J:306407
decreased susceptibility to bacterial infection J:306407
decreased susceptibility to bacterial infection induced morbidity/mortality J:306407
increased circulating CXCL10 level J:306407
Srpk3tm1b(KOMP)Wtsi/Y
(C57BL/6N-Srpk3tm1b(KOMP)Wtsi/Ucd)
increased monocyte cell number J:211773
Srpxtm1Hzi/Srpxtm1Hzi
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal lymphocyte morphology J:119999
enlarged spleen J:119999
SrrRgsc34/Srr+
(involves: C57BL/6JJcl * DBA/2JJcl)
abnormal neutrophil physiology J:133634
Srrttm1.1Thsn/Srrttm1.2Thsn
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal thymus physiology J:152729
increased splenocyte apoptosis J:152729
Srsf2tm1.1Oaw/Srsf2+
Tg(Mx1-cre)1Cgn/?

(B6.Cg-Tg(Mx1-cre)1Cgn Srsf2tm1.1Oaw)
abnormal myelopoiesis J:221404
abnormal neutrophil morphology J:221404
decreased B cell number J:221404
failure of myelopoiesis J:221404
Srsf2tm1Xdfu/Srsf2+
Tg(Lck-cre)I57Jxm/?

(involves: 129S4/SvJae * 129X1/SvJ * ICR)
decreased thymocyte number J:88668
decreased thymus weight J:88668
Srsf2tm1Xdfu/Srsf2tm1Xdfu
Tg(Lck-cre)I57Jxm/?

(involves: 129S4/SvJae * 129X1/SvJ * ICR)
abnormal spleen white pulp morphology J:88668
abnormal T cell differentiation J:88668
absent thymus corticomedullary boundary J:88668
decreased double-positive T cell number J:88668
decreased T cell number J:88668
decreased thymocyte number J:88668
increased double-negative T cell number J:88668
small thymus J:88668
Srsf2tm1Xdfu/Srsf2tm1Xdfu
Tg(Mx1-cre)1Cgn/?

(involves: 129S4/SvJae * C57BL/6J * CBA/J)
bone marrow failure J:221404
Srsf3tm1Pjln/Srsf3tm1Pjln
Cd79atm1(cre)Reth/Cd79a+

(involves: 129P2/OlaHsd * BALB/c)
decreased B cell number J:113645
decreased pre-B cell number J:113645
decreased pro-B cell number J:113645
Srsf3tm1Pjln/Srsf3tm1Pjln
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: BALB/c * C57BL/6 * DBA)
abnormal thymus development J:205756
Srsf5em1Nju/Srsf5em1Nju
(C57BL/6JGpt-Srsf5em1Nju)
small spleen J:311867
Srxn1tm1Mtol/Srxn1tm1Mtol
(either: B6.129S2-Srxn1tm1Mtol or (involves: 129S2/SvPasCrl * C57BL/6))
increased susceptibility to endotoxin shock J:199277
Ss18l1em1Zqi/Ss18l1+
(involves: C57BL/6)
increased microglial cell activation J:278840
Ss18l1em1Zqi/Ss18l1em1Zqi
(involves: C57BL/6)
increased microglial cell activation J:278840
Ss18l1em2Zqi/Ss18l1em2Zqi
(involves: C57BL/6)
increased microglial cell activation J:278840
Ssbtm1Rjma/Ssbtm2.1Rjma
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S/SvEv * BALB/c)
arrested B cell differentiation J:207687
decreased B cell number J:207687
decreased IgG level J:207687
decreased IgM level J:207687
decreased spleen weight J:207687
immune system phenotype J:207687
small spleen J:207687
Ssbp2tm1Lana/Ssbp2tm1Lana
(involves: 129S/SvEv * C57BL/6)
arteritis J:162035
decreased lymphocyte cell number J:162035
increased pre-B cell number J:162035
Ssbp2tm1Lana/Ssbp2tm1Lana
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129S/SvEv * 129S2/SvPas * BALB/c * C57BL/6)
thymus hypoplasia J:162035
Ssh2em1(IMPC)J/Ssh2em1(IMPC)J
(C57BL/6NJ-Ssh2em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ssial1NOD/Ssial1NOD
(involves: C57BL/6J * NOD)
periinsulitis J:11442
salivary gland inflammation J:75908
Ssial2NOD/?
(involves: C57BL/6J * NOD)
salivary gland inflammation J:75908
Ssial3NOD/Ssial3NOD
(involves: C57BL/6J * NOD)
salivary gland inflammation J:75908
Ssial4C57BL/6/Ssial4NOD
(involves: C57BL/6J * NOD)
salivary gland inflammation J:75908
Ssial4NOD/Ssial4NOD
(involves: C57BL/6J * NOD)
salivary gland inflammation J:75908
Sspntm1b(EUCOMM)Hmgu/Sspntm1b(EUCOMM)Hmgu
(C57BL/6N-Sspntm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Ssr1em1(IMPC)Mbp/Ssr1+
(C57BL/6N-Ssr1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Ssr2tm1b(EUCOMM)Wtsi/Ssr2tm1b(EUCOMM)Wtsi
(C57BL/6N-Ssr2tm1b(EUCOMM)Wtsi/Wtsi)
abnormal thymus morphology J:239583
Sst1C3HeB/FeJ/Sst1C3HeB/FeJ
(involves: C3HeB/FeJ * C57BL/6J)
increased susceptibility to bacterial infection J:63410
Sst1C3HeB/FeJ/Sst1C3HeB/FeJ
(B6.C3-Sst1C3HeB/FejKrmn/Mmnc)
increased susceptibility to bacterial infection J:313901
increased susceptibility to bacterial infection induced morbidity/mortality J:313901
Sst1C3HeB/FeJ/Sst1C57BL/6J
(involves: C3HeB/FeJ * C57BL/6J)
decreased susceptibility to bacterial infection J:63410
Sst1C57BL/6J/Sst1C57BL/6J
(involves: C3HeB/FeJ * C57BL/6J)
decreased susceptibility to bacterial infection J:63410, J:93705
Ssttm1Low/Ssttm1Low
(B6.129P2-Ssttm1Low)
immune system phenotype J:126384
Sstr2em1(IMPC)Mbp/Sstr2em1(IMPC)Mbp
(C57BL/6N-Sstr2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Sstr4tm1Szo/Sstr4tm1Szo
(B6.129P2-Sstr4tm1Szo)
abnormal granulocyte morphology J:152015
abnormal neutrophil physiology J:152015
increased interferon-gamma secretion J:152015
increased interleukin-1 beta secretion J:152015
increased susceptibility to type IV hypersensitivity reaction J:152015
increased tumor necrosis factor secretion J:152015
Ssu72tm1Cwl/Ssu72tm1Cwl
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(B6.Cg-Ssu72tm1Cwl Speer6-ps1Tg(Alb-cre)21Mgn)
liver inflammation J:309624
St3gal2tm1Jxm/St3gal2tm1Jxm
(Not Specified)
decreased T cell proliferation J:217719
increased spleen germinal center size J:217719
increased T cell number J:217719
St3gal4tm1.1Jxm/St3gal4tm1.1Jxm
(B6.129-St3gal4tm1.1Jxm)
abnormal leukocyte tethering or rolling J:117085
abnormal response to infection J:136946
St3gal4tm1.1Jxm/St3gal4tm1.1Jxm
(involves: 129S1/Sv * 129X1/SvJ)
abnormal leukocyte migration J:189086
decreased lymphocyte cell number J:189086
immune system phenotype J:189086
St3gal4tm1.1Jxm/St3gal4tm1.1Jxm
St3gal6tm1.1Jxm/St3gal6tm1.1Jxm

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal leukocyte migration J:189086
decreased lymphocyte cell number J:189086
impaired leukocyte tethering or rolling J:189086
impaired neutrophil recruitment J:189086
increased leukocyte cell number J:189086
increased neutrophil cell number J:189086
St3gal6tm1.1Jxm/St3gal6tm1.1Jxm
(B6.Cg-St3gal6tm1.1Jxm)
immune system phenotype J:189086
impaired leukocyte tethering or rolling J:189086
impaired neutrophil recruitment J:189086
St6gal1tm1Jlau/St6gal1tm1Jlau
(129S4/SvJae-St6gal1tm1Jlau)
abnormal neutrophil physiology J:140702
increased susceptibility to bacterial infection J:140702
St6gal1tm1Jlau/St6gal1tm1Jlau
(B6.129S4-St6gal1tm1Jlau)
abnormal myelopoiesis J:140547
abnormal neutrophil physiology J:140547
increased neutrophil cell number J:140547
peritoneal inflammation J:140547
St6gal1tm1Jxm/St6gal1tm1Jxm
(involves: 129S1/Sv * 129X1/SvJ)
abnormal dendritic cell physiology J:132991
decreased marginal zone B cell number J:132991
decreased transitional stage B cell number J:132991
increased neutrophil cell number J:140547
peritoneal inflammation J:140547
St6galnac1em1Len/St6galnac1em1Len
(Not Specified)
increased susceptibility to colitis induced morbidity/mortality J:324883
St6galnac2tm1.1Cfg/St6galnac2tm1.1Cfg
(involves: 129S1/Sv * 129X1/SvJ)
decreased IgA level J:217719
increased B cell proliferation J:217719
increased pre-B cell number J:217719
increased spleen germinal center size J:217719
St6galnac3em1Staka/St6galnac3em1Staka
St6galnac4em1Staka/St6galnac4em1Staka

(C57BL/6J-St6galnac3em1Staka St6galnac4em1Staka)
lymph node hemorrhage J:340690
St8sia1tm1Kfk/St8sia1tm1Kfk
(Not Specified)
decreased CD8-positive, alpha-beta T cell number J:73818
immune system phenotype J:73818
increased T cell proliferation J:73818
St8sia6em1(IMPC)Mbp/St8sia6em1(IMPC)Mbp
(C57BL/6N-St8sia6em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
St14tm1Bug/St14tm1Bug
(involves: 129P2/OlaHsd * Black Swiss)
decreased double-positive T cell number J:87125
increased thymocyte apoptosis J:87125
St14tm2Bug/St14tm3Bug
Tg(MMTV-cre)4Mam/0

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/NJ * N:Black Swiss)
abnormal chemokine secretion J:213072
abnormal cytokine secretion J:213072
decreased CD4-positive, alpha-beta T cell number J:213072
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:213072
decreased CD8-positive, alpha-beta T cell number J:213072
decreased regulatory T cell number J:213072
increased anti-nuclear antigen antibody level J:213072
increased autoantibody level J:213072
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:213072
increased effector memory CD4-positive, alpha-beta T cell number J:213072
increased effector memory CD8-positive, alpha-beta T cell number J:213072
lacrimal gland inflammation J:213072
submandibular gland inflammation J:213072
St14tm2Bug/St14tm3Bug
Tg(Vil1-cre)997Gum/0

(involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL)
colitis J:153070
St14tm3Bug/St14tm3Bug
(involves: 129S6/SvEvTac)
immune system phenotype J:213072
Stag1em1(IMPC)Mbp/Stag1+
(C57BL/6N-Stag1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
small spleen J:211773
Stag2tm1.1Soga/Y
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6J * C57BL/6N * CBA/J)
decreased B cell number J:289000
decreased leukocyte cell number J:289000
enlarged spleen J:289000
increased granulocyte number J:289000
increased monocyte cell number J:289000
Stamtm2Sug/Stamtm2Sug
Stam2tm1Sug/Stam2tm1Sug
Tg(Lck-cre)I57Jxm/0

(involves: 129S4/SvJae * C57BL/6 * ICR)
decreased T cell number J:80617
decreased T cell proliferation J:80617
Stambptm1Sug/Stambptm1Sug
(involves: 129S4/SvJae * C57BL/6)
immune system phenotype J:72940
Stard7tm1a(EUCOMM)Wtsi/Stard7+
(involves: C57BL/6N)
dermatitis J:242746
immune system phenotype J:242746
increased CD11b-high dendritic cell number J:242746
increased susceptibility to type I hypersensitivity reaction J:242746
lung inflammation J:242746
Stard13tm1a(KOMP)Wtsi/Stard13tm1a(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
increased susceptibility to bacterial infection J:213427
lymphoid hyperplasia J:213427
Stat1fae/Stat1fae
(C57BL/6JSfdAnu-Stat1fae/Anu)
abnormal T cell activation J:105311
abnormal T-helper 2 physiology J:105311
increased IgG level J:105311
Stat1m1Anu/Stat1m1Anu
(C57BL/6JSfdAnu-Stat1m1Anu)
abnormal response to infection J:104190
Stat1m1Btlr/Stat1m1Btlr
(C57BL/6J-Stat1m1Btlr)
abnormal macrophage physiology J:105543
increased susceptibility to Herpesvirales infection J:105543
increased susceptibility to Riboviria infection J:105543
Stat1m2Btlr/Stat1m2Btlr
(C57BL/6J-Stat1m2Btlr)
decreased interferon-gamma secretion J:134096
decreased NK cell degranulation J:134096
impaired natural killer cell mediated cytotoxicity J:134096
increased susceptibility to Herpesvirales infection J:134096
Stat1m3Btlr/Stat1m3Btlr
(C57BL/6J-Stat1m3Btlr)
impaired natural killer cell mediated cytotoxicity J:254835
Stat1m4Btlr/Stat1m4Btlr
(C57BL/6J-Stat1m4Btlr)
abnormal CD8-positive, naive alpha-beta T cell number J:264800
decreased B cell number J:264800
decreased B-1 B cell number J:264800
decreased CD8-positive, alpha-beta T cell number J:264800
decreased NK cell number J:264800
decreased single-positive T cell number J:264800
increased CD4-positive, alpha-beta T cell number J:264800
increased effector memory CD8-positive, alpha-beta T cell number J:264800
increased NK T cell number J:264800
Stat1m5Btlr/Stat1m5Btlr
(C57BL/6J-Stat1m5Btlr)
abnormal CD4-positive T cell differentiation J:274938
abnormal CD8-positive, alpha-beta T cell differentiation J:274938
abnormal T cell differentiation J:274938
decreased CD8-positive, naive alpha-beta T cell number J:274938
decreased cytotoxic T cell cytolysis J:274938
increased CD4-positive, alpha-beta T cell number J:274938
increased effector memory CD4-positive, alpha-beta T cell number J:274938
increased effector memory CD8-positive, alpha-beta T cell number J:274938
increased T cell number J:274938
Stat1tm1Dlv/Stat1tm1Dlv
(either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * CD-1))
abnormal leukocyte physiology J:31325
increased susceptibility to Coronaviridae infection J:31325
increased susceptibility to Riboviria infection J:31325
Stat1tm1Dlv/Stat1tm1Dlv
(B6.129-Stat1tm1Dlv)
increased susceptibility to Herpesvirales infection J:81243
increased susceptibility to Togaviridae infection J:81243
Stat1tm1Dlv/Stat1tm1Dlv
(involves: 129S/SvEv)
abnormal MHC II cell surface expression on macrophages J:130622
decreased level of surface class I molecules J:130622
decreased susceptibility to endotoxin shock J:130622
immune system phenotype J:99728
increased circulating interferon-gamma level J:130622
increased susceptibility to bacterial infection J:130622
increased susceptibility to Riboviria infection J:130622
Stat1tm1Dlv/Stat1tm1Dlv
(B6.129S-Stat1tm1Dlv)
abnormal NK cell physiology J:79552
impaired natural killer cell mediated cytotoxicity J:79552
increased circulating interferon-gamma level J:79552
increased circulating interleukin-12b level J:79552
Stat1tm1Dlv/Stat1tm1Dlv
Tg(ANPEP)270Mmul/Tg(ANPEP)270Mmul

(involves: 129S/SvEv * ICR)
increased susceptibility to Coronaviridae infection J:99728
Stat1tm1Dlv/Stat1tm1Dlv
Tg(ANPEP)861Mmul/Tg(ANPEP)861Mmul

(involves: 129S/SvEv * ICR)
increased susceptibility to Coronaviridae infection J:99728
Stat1tm1Rds/Stat1tm1Rds
(either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6))
increased susceptibility to bacterial infection J:31326
increased susceptibility to Riboviria infection J:31326
Stat1tm1Rds/Stat1tm1Rds
(involves: 129)
increased susceptibility to Herpesvirales infection J:81243
increased susceptibility to Riboviria infection J:66564
increased susceptibility to Togaviridae infection J:81243
Stat1tm1Rds/Stat1tm1Rds
(129S6/SvEv-Stat1tm1Rds/Tac)
abnormal macrophage physiology J:136368
abnormal osteoclast differentiation J:131353
bronchiolitis J:286237
decreased circulating interferon-gamma level J:122801
decreased interleukin-1 beta secretion J:136368
increased NK T cell number J:122801
increased susceptibility to Coronaviridae infection J:286237
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:286237
lung inflammation J:286237
peritoneal inflammation J:286237
pleuritis J:286237
Stat1tm1Rds/Stat1tm1Rds
(B6.129-Stat1tm1Rds)
increased osteoclast cell number J:84894
Stat1tm1Rds/Stat1tm1Rds
Stat2tm1Shnd/Stat2tm1Shnd

(involves: 129/Sv * 129S1/Sv * 129X1/SvJ)
increased susceptibility to Riboviria infection J:66564
Stat1tm1Rds/Stat1tm1Rds
Stat3tm2Aki/Stat3tm2Aki
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
colitis J:83280
increased CD4-positive, alpha-beta T cell number J:83280
increased interferon-gamma secretion J:83280
increased interleukin-6 secretion J:83280
increased tumor necrosis factor secretion J:83280
Stat1tm1Tdec/Stat1tm1Tdec
(involves: 129P2/OlaHsd * BALB/c)
abnormal macrophage physiology J:130622
abnormal MHC II cell surface expression on macrophages J:130622
decreased susceptibility to endotoxin shock J:130622
increased susceptibility to bacterial infection J:130622
increased susceptibility to Riboviria infection J:130622
Stat1tm1Uvin/Stat1tm1Uvin
(involves: 129 * C57BL/6)
increased macrophage nitric oxide production J:174863
Stat1tm2.1Uvin/Stat1tm2.1Uvin
(B6.129P2-Stat1tm2.1Uvin)
decreased susceptibility to endotoxin shock J:209388
immune system phenotype J:209388
increased susceptibility to bacterial infection J:209388
increased susceptibility to bacterial infection induced morbidity/mortality J:209388
Stat1tm2b(EUCOMM)Wtsi/Stat1tm2b(EUCOMM)Wtsi
(C57BL/6N-Stat1tm2b(EUCOMM)Wtsi/Orl)
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased large unstained cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Stat2m1Btlr/Stat2m1Btlr
(C57BL/6J-Stat2m1Btlr)
decreased CD8-positive, alpha-beta T cell number J:265265
decreased central memory CD8 positive, alpha-beta T cell number J:265265
decreased single-positive T cell number J:265265
Stat2p117/Stat2p117
(C57BL/6J-Stat2P117)
abnormal level of surface class II molecules J:164049
decreased dendritic cell number J:164049
decreased level of surface class I molecules J:164049
decreased plasmacytoid dendritic cell number J:164049
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:164049
Stat2tm1.1(STAT2)Diam/Stat2tm1.1(STAT2)Diam
(C57BL/6-Stat2tm1.1(STAT2)Diam)
increased susceptibility to Flaviviridae infection J:261503
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:261503
Stat2tm1Jdf/Stat2tm1Jdf
Tg(DO11.10)10Dlo/0

(C.Cg-Stat2tm1Jdf Tg(DO11.10)10Dlo)
immune system phenotype J:95855
Stat2tm1Shnd/Stat2tm1Shnd
(involves: 129S1/Sv * 129X1/SvJ)
abnormal T cell differentiation J:66564
increased susceptibility to Riboviria infection J:66564
Stat3tm1Aki/Stat3tm1Aki
Tg(Tek-cre)12Flv/0

(involves: 129P2/OlaHsd * C3H * C57BL/6)
abnormal interleukin level J:123351
Stat3tm1Desi/Stat3tm1Desi
(involves: 129X1/SvJ * C57BL/6)
increased susceptibility to endotoxin shock J:77307
Stat3tm1Dlv/Stat3tm1Dlv
Tg(Cd4-cre)1Cwi/?

(involves: 129 * C57BL/6 * DBA/2)
abnormal CD4-positive T cell differentiation J:124293
abnormal gut-associated lymphoid tissue morphology J:124293
decreased interleukin-17 secretion J:124293
increased interferon-gamma secretion J:124293
Stat3tm1Dlv/Stat3tm1Dlv
Tg(Csf1r-icre)1Jwp/0

(involves: 129P2/OlaHsd * C57BL/6 * FVB)
abnormal acute inflammation J:156593
abnormal inflammatory response J:156593
colitis J:156593
increased granulocyte number J:156593
increased macrophage cell number J:156593
increased T cell number J:156593
Stat3tm1Dlv/Stat3tm1Dlv
Tg(MMTV-cre)4Mam/0

(involves: 129P2/OlaHsd * C57BL/6J * FVB)
decreased T-helper 17 cell number J:120176
Stat3tm1Dnl/Stat3tm1Dlv
(involves: C57BL/6)
decreased thymocyte number J:87599
increased thymocyte apoptosis J:87599
Stat3tm1Flv/Stat3tm1Flv
Tg(Tek-cre)1Xyfu/0

(involves: C57BL/6)
abnormal cytokine secretion J:86655
increased susceptibility to endotoxin shock J:86655
Stat3tm1Flv/Stat3tm1Flv
Tg(Tek-cre)12Flv/0

(involves: 129 * C3H * C57BL/6)
abnormal inflammatory response J:81973
abnormal innate immunity J:81973
abnormal T-helper 1 physiology J:81973
cecum inflammation J:81973
colitis J:81973
granulomatous inflammation J:81973
ileum inflammation J:81973
increased circulating interferon-gamma level J:81973
increased circulating tumor necrosis factor level J:81973
increased leukocyte cell number J:81973
intestinal inflammation J:81973
liver inflammation J:81973
Stat3tm1Vpo/Stat3tm1Vpo
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * BALB/cAn * C57BL/6 * CBA)
abnormal macrophage physiology J:89194
increased interleukin-6 secretion J:89194
increased tumor necrosis factor secretion J:89194
Stat3tm1Vpo/Stat3tm2Vpo
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA * BALB/cAn)
abnormal macrophage physiology J:89194
increased interleukin-6 secretion J:89194
increased tumor necrosis factor secretion J:89194
Stat3tm1Xyfu/Stat3+
Tg(Myh6-cre)2182Mds/0

(involves: 129S1/Sv * FVB/N)
increased susceptibility to endotoxin shock J:86400
increased tumor necrosis factor secretion J:86400
Stat3tm1Xyfu/Stat3tm1.1Xyfu
Tg(Myh6-cre)2182Mds/0

(involves: 129S1/Sv * FVB/N)
increased susceptibility to endotoxin shock J:86400
increased tumor necrosis factor secretion J:86400
Stat3tm1Xyfu/Stat3tm1.1Xyfu
Tg(Ttr-cre)10-3Xyfu/?

(involves: 129S1/Sv * C57BL/6)
increased monocyte cell number J:128719
increased neutrophil cell number J:128719
Stat3tm2Aki/Stat3tm2Aki
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal response to infection J:122213
Stat3tm2Aki/Stat3tm2Aki
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
colitis J:83280
increased CD4-positive, alpha-beta T cell number J:83280
increased dendritic cell number J:83280
increased interferon-gamma secretion J:83280
increased interleukin-12 secretion J:83280
increased macrophage cell number J:83280
Stat3tm2Aki/Stat3tm2Aki
Tg(KRT5-cre)1Tak/0

(involves: 129P2/OlaHsd * C3H * C57BL/6)
conjunctivitis J:194832
dermatitis J:194832
lacrimal gland inflammation J:194832
Stat3tm2Aki/Stat3tm2Aki
Tg(Lck-cre)1Jtak/0

(involves: 129P2/OlaHsd)
decreased T cell proliferation J:50443
increased T cell apoptosis J:50443
Stat3tm2Aki/Stat3tm2Aki
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0

(involves: 129 * 129P2/OlaHsd * C57BL/6)
abnormal cytokine level J:87622
lung inflammation J:87622
Stat3tm2Aki/Stat3tm2Aki
Tlr4tm1Aki/Tlr4tm1Aki
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
colitis J:83280
decreased interferon-gamma secretion J:83280
decreased susceptibility to endotoxin shock J:83280
Stat3tm2Aki/Stat3tm2Aki
Tnftm1Sek/Tnftm1Sek
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
colitis J:83280
increased interferon-gamma secretion J:83280
increased interleukin-6 secretion J:83280
increased interleukin-12b secretion J:83280
Stat3tm3Vpo/Stat3tm3Vpo
(involves: C57BL/6 * CBA * BALB/cAn)
abnormal macrophage physiology J:89194
Stat4ity14/Stat4ity14
(involves: 129S1/Sv * 129X1/SvJ)
decreased circulating interferon-gamma level J:207092
decreased interferon-gamma secretion J:207092
increased circulating interleukin-12 level J:207092
increased susceptibility to bacterial infection J:207092
increased susceptibility to bacterial infection induced morbidity/mortality J:207092
Stat4ity14/Stat4tm1Gru
(involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ)
increased susceptibility to bacterial infection induced morbidity/mortality J:207092
Stat4tm1Gru/Stat4tm1Gru
(involves: 129S2/SvPas * BALB/c)
abnormal lymphocyte physiology J:34059
abnormal NK cell physiology J:34059
abnormal T cell proliferation J:34059
abnormal T-helper 1 physiology J:34059
abnormal T-helper 2 physiology J:34059
decreased circulating interferon-gamma level J:163843
decreased interferon-gamma secretion J:34059
increased susceptibility to bacterial infection J:163843
increased susceptibility to bacterial infection induced morbidity/mortality J:163843
Stat4tm1Gru/Stat4tm1Gru
(NOD.129S2-Stat4tm1Gru)
abnormal inflammatory response J:90600
decreased circulating interferon-gamma level J:90600
decreased circulating interleukin-2 level J:90600
decreased susceptibility to autoimmune diabetes J:90600
Stat4tm1Gru/Stat4tm1Gru
(C.129S2-Stat4tm1Gru)
abnormal CD4-positive T cell differentiation J:143729
decreased circulating interferon-gamma level J:90600
decreased circulating interleukin-2 level J:90600
Stat4tm1Gru/Stat4tm1Gru
(involves: 129S2/SvPas)
abnormal cytokine secretion J:112600
Stat4tm1Gru/Stat4tm1Gru
Tg(Ins2-GP)34-20Olds/0

(involves: 129S2/SvPas * BALB/c * C57BL/6)
abnormal susceptibility to autoimmune disorder J:107047
Stat4tm1Gru/Stat4tm1Gru
Tg(Ins2-NP)25-3Olds/0

(involves: 129S2/SvPas * BALB/c * C57BL/6)
abnormal cytotoxic T cell physiology J:107047
decreased interferon-gamma secretion J:107047
decreased susceptibility to autoimmune diabetes J:107047
insulitis J:107047
Stat4tm1Jni/Stat4tm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
abnormal NK cell physiology J:79552
decreased circulating interferon-gamma level J:79552
decreased susceptibility to autoimmune diabetes J:96338
increased interleukin-4 secretion J:96338
Stat4tm1Jni/Stat4tm1Jni
Stat6tm1Jni/Stat6tm1Jni

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
decreased interleukin-4 secretion J:96338
increased interferon-gamma secretion J:96338
increased susceptibility to autoimmune diabetes J:96338
Stat5atm1.1Wjl/Stat5atm1.1Wjl
Stat5btm2.1Wjl/Stat5btm2.1Wjl

(involves: 129S6/SvEvTac * C57BL/6J * FVB/N)
abnormal leukocyte morphology J:187325
abnormal regulatory T cell physiology J:187325
abnormal T cell subpopulation ratio J:187325
decreased CD8-positive, alpha-beta T cell number J:187325
decreased NK cell number J:187325
decreased T cell proliferation J:187325
increased T cell apoptosis J:187325
Stat5atm1Jni/Stat5atm1Jni
Stat5btm2Jni/Stat5btm2Jni

(either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ))
abnormal myelopoiesis J:77412
decreased leukocyte cell number J:77412
decreased T cell number J:77412
increased neutrophil cell number J:77412
Stat5atm1Jni/Stat5atm1Jni
Stat5btm2Jni/Stat5btm2Jni

(involves: 129 * C57BL/6)
abnormal mast cell differentiation J:84889
abnormal mast cell physiology J:84889
absent mast cells J:84889
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:122463
Stat5atm1Mam/Stat5atm1Mam
(C.129S6-Stat5atm1Mam)
abnormal mast cell differentiation J:101855
abnormal mast cell morphology J:101855
decreased mast cell number J:101855
Stat5atm1Mam/Stat5atm1Mam
(involves: 129S6/SvEvTac * C57BL/6)
decreased NK cell number J:112035
decreased splenocyte number J:112035
impaired natural killer cell mediated cytotoxicity J:112035
Stat5atm2Mam/Stat5atm2Mam
Stat5btm1Mam/Stat5b+

(involves: 129S6/SvEvTac)
abnormal lymphopoiesis J:258967
Stat5atm2Mam/Stat5atm2Mam
Stat5btm1Mam/Stat5btm1Mam
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2)
increased circulating interleukin-17 level J:120176
increased interleukin-17 secretion J:120176
Stat5atm2Mam/Stat5atm2Mam
Stat5btm1Mam/Stat5btm1Mam
Tg(Lck-cre)I57Jxm/0

(involves: 129 * 129S6/SvEvTac * C57BL/6 * ICR)
abnormal acute inflammation J:122463
abnormal T cell subpopulation ratio J:122463
decreased CD8-positive, alpha-beta T cell number J:122463
enlarged spleen J:122463
Stat5atm2Mam/Stat5atm2Mam
Stat5btm1Mam/Stat5btm1Mam
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
abnormal leukopoiesis J:155489
abnormal neutrophil differentiation J:155489
abnormal neutrophil physiology J:155489
decreased leukocyte cell number J:155489
decreased lymphocyte cell number J:155489
decreased monocyte cell number J:155489
decreased neutrophil cell number J:155489
Stat5btm1Hwd/Stat5btm1Hwd
(involves: C57BL/6)
abnormal double-negative T cell morphology J:112035
abnormal lymphocyte cell number J:112035
abnormal lymphocyte morphology J:112035
decreased CD8-positive, alpha-beta T cell number J:112035
decreased NK cell number J:112035
decreased splenocyte number J:112035
decreased T cell proliferation J:112035
decreased thymocyte number J:112035
impaired natural killer cell mediated cytotoxicity J:112035
Stat5btm1Mam/Stat5btm1Mam
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2)
increased circulating interleukin-17 level J:120176
increased interleukin-17 secretion J:120176
Stat5btm1Mam/Stat5btm1Mam
Tg(Lck-cre)I57Jxm/0

(involves: 129 * 129S6/SvEvTac * C57BL/6 * ICR)
abnormal acute inflammation J:122463
abnormal T cell subpopulation ratio J:122463
decreased CD8-positive, alpha-beta T cell number J:122463
enlarged spleen J:122463
Stat5btm1Mam/Stat5btm1Mam
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
abnormal leukopoiesis J:155489
abnormal neutrophil differentiation J:155489
abnormal neutrophil physiology J:155489
decreased leukocyte cell number J:155489
decreased lymphocyte cell number J:155489
decreased monocyte cell number J:155489
decreased neutrophil cell number J:155489
Stat6tm1Aki/Stat6tm1Aki
(involves: 129P2/OlaHsd)
abnormal T-helper 2 physiology J:32561
decreased B cell proliferation J:32561
decreased IgE level J:32561
decreased IgG1 level J:32561
decreased T cell proliferation J:32561
decreased T-helper 2 cell number J:172134
increased IgA level J:32561
increased IgG level J:32561
Stat6tm1Aki/Stat6tm1Aki
(C.129P2-Stat6tm1Aki Nfkbiztm1Aki)
skin inflammation J:141704
Stat6tm1Aki/Stat6tm1Aki
Tg(KRT14-CASP1)1Miz/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased IgE level J:78602
decreased IgG1 level J:78602
dermatitis J:78602
increased circulating interleukin-18 level J:78602
Stat6tm1Gru/Stat6+
Tg(Scgb1a1-Il13)2Eli/?

(involves: 129S2/SvPas * C57BL/6 * CBA)
respiratory system inflammation J:132385
Stat6tm1Gru/Stat6tm1Gru
(C.129S2-Stat6tm1Gru/J)
abnormal CD4-positive T cell differentiation J:204829
abnormal CD8-positive, alpha beta T cell morphology J:125259
abnormal humoral immune response J:107370
decreased IgA level J:107370
decreased IgG3 level J:107370
decreased IgM level J:107370
decreased interleukin-4 secretion J:107370
decreased susceptibility to Herpesvirales infection J:107370
increased interferon-gamma secretion J:107370
increased interleukin-2 secretion J:107370
Stat6tm1Gru/Stat6tm1Gru
(129S2/SvPas-Stat6tm1Gru)
abnormal interleukin secretion J:31932
abnormal T-helper 2 cell differentiation J:31932
decreased IgE level J:31932
decreased interleukin-4 secretion J:31932
decreased interleukin-5 secretion J:31932
decreased T cell proliferation J:31932
Stat6tm1Gru/Stat6tm1Gru
(involves: 129S2/SvPas)
abnormal cytokine secretion J:112600
Stat6tm1Gru/Stat6tm1Gru
(involves: 129S2/SvPas * BALB/c)
abnormal acute inflammation J:85386
abnormal granulocyte physiology J:85386
abnormal macrophage physiology J:85386
immune system phenotype J:85386
impaired eosinophil chemotaxis J:85386
impaired neutrophil chemotaxis J:85386
increased circulating tumor necrosis factor level J:85386
Stat6tm1Gru/Stat6tm1Gru
(C.129S2-Stat6tm1Gru)
abnormal circulating interleukin level J:66222
abnormal circulating interleukin-4 level J:66222
abnormal circulating interleukin-5 level J:66222
abnormal cytotoxic T cell physiology J:65894
abnormal immune serum protein physiology J:66222
abnormal immunoglobulin level J:66222
abnormal leukocyte migration J:74497
abnormal leukocyte physiology J:74497
decreased IgE level J:74497, J:66222
decreased IgG1 level J:66222
impaired eosinophil recruitment J:66222
increased IgG2a level J:66222
Stat6tm1Jni/Stat6tm1Jni
(involves: 129S/SvEv)
abnormal B cell physiology J:32607
abnormal B cell proliferation J:32607
abnormal class switch recombination J:32607
abnormal level of surface class II molecules J:32607
abnormal T-helper 1 cell differentiation J:32607
abnormal T-helper 2 cell differentiation J:32607
increased B cell apoptosis J:146533
Stat6tm1Jni/Stat6tm1Jni
(involves: 129S/SvEv * C57BL/6)
abnormal mast cell morphology J:110429
abnormal T-helper 1 cell differentiation J:51096
decreased IgE level J:51096
decreased IgG1 level J:51096
decreased interleukin-4 secretion J:96338
decreased susceptibility to autoimmune diabetes J:96338
increased IgE level J:110429
increased IgG1 level J:110429
increased IgG2a level J:51096
increased interferon-gamma secretion J:51096, J:96338
increased interleukin-12 secretion J:51096
increased susceptibility to parasitic infection J:110429
Stau2em1(IMPC)Mbp/Stau2em1(IMPC)Mbp
(C57BL/6N-Stau2em1(IMPC)Mbp/MbpMmucd)
increased monocyte cell number J:211773
Steap3fred/Steap3fred
(C57BL/6-Steap3fred)
enlarged spleen J:145194
Steap3tm1.1Atel/Steap3tm1.1Atel
(involves: C57BL/6)
abnormal spleen morphology J:154356
abnormal spleen red pulp morphology J:154356
decreased splenocyte apoptosis J:154356
increased spleen weight J:154356
increased spleen white pulp amount J:154356
Steap4tm1Dgen/Steap4tm1Dgen
(involves: 129P2/OlaHsd)
increased macrophage cell number J:187736
Stia1NOD/ShiLtDoi/?
(involves: C57BL/6J * NOD/LtDoi)
increased inflammatory response J:70882
Stia2C57BL/6J/Stia2C57BL/6J
(involves: C57BL/6J * NOD/LtDoi)
increased inflammatory response J:70882
Stia2C57BL/6J/Stia2NOD/ShiLtDoi
(involves: C57BL/6J * NOD/LtDoi)
increased inflammatory response J:70882
Stim1em1(IMPC)Mbp/Stim1+
(C57BL/6N-Stim1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Stim1Sax/Stim1+
(involves: C3HeB/FeJ * C57BL/6)
abnormal thrombopoiesis J:127381
enlarged spleen J:127381
immune system phenotype J:127381
increased spleen red pulp amount J:127381
Stim1tm1.1Kuro/Stim1+
(C57BL/6-Stim1tm1.1Kuro)
decreased susceptibility to type I hypersensitivity reaction J:130477
Stim1tm1.1Kuro/Stim1tm1.1Kuro
(C57BL/6-Stim1tm1.1Kuro)
abnormal cytokine secretion J:130477
abnormal interleukin secretion J:130477
decreased interleukin-6 secretion J:130477
decreased interleukin-13 secretion J:130477
decreased mast cell degranulation J:130477
decreased tumor necrosis factor secretion J:130477
Stim1tm1.1Pg/Stim1+
(involves: C57BL/6)
decreased Ly6C low monocyte number J:285187
decreased NK cell number J:285187
enlarged spleen J:285187
increased Ly6C high monocyte number J:285187
Stim1tm1Kuro/Stim1tm1Kuro
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6)
abnormal B cell physiology J:172608
decreased B cell proliferation J:172608
decreased interleukin-10 secretion J:172608
Stim1tm1Kuro/Stim1tm1Kuro
Stim2tm1.1Kuro/Stim2tm1.1Kuro
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6)
abnormal B cell physiology J:172608
decreased B cell proliferation J:172608
decreased interleukin-10 secretion J:172608
immune system phenotype J:172608
increased CD4-positive, alpha-beta T cell number J:172608
increased CD8-positive, alpha-beta T cell number J:172608
increased interferon-gamma secretion J:172608
increased interleukin-10 secretion J:172608
increased interleukin-17 secretion J:172608
increased regulatory T cell number J:172608
increased susceptibility to experimental autoimmune encephalomyelitis J:172608
Stim1tm1Rao/Stim1tm1Rao
Stim2tm1Rao/Stim2tm1Rao
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal B cell differentiation J:133262
abnormal CD4-positive, alpha-beta T cell physiology J:133262
abnormal granulocyte morphology J:133262
abnormal immune system morphology J:133262
abnormal immune system physiology J:133262
abnormal lymph organ size J:133262
abnormal T cell differentiation J:133262
blepharitis J:133262
decreased interferon-gamma secretion J:133262
decreased interleukin-2 secretion J:133262
decreased regulatory T cell number J:133262
decreased T cell proliferation J:133262
dermatitis J:133262
enlarged lymph nodes J:133262
enlarged spleen J:133262
increased germinal center B cell number J:133262
increased IgG1 level J:133262
increased lymphocyte cell number J:133262
increased spleen germinal center number J:133262
Stim1tm1Rao/Stim1tm1Rao
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal CD4-positive, alpha-beta T cell physiology J:133262
decreased interleukin-2 secretion J:133262
increased lymphocyte cell number J:133262
Stim1tm3Ics/Stim1+
(involves: C57BL/6N)
decreased lymphocyte cell number J:277842
decreased NK T cell number J:277842
decreased regulatory T cell number J:277842
increased monocyte cell number J:277842
increased neutrophil cell number J:277842
increased spleen weight J:277842
myositis J:277842
Stim2tm1.1Kuro/Stim2tm1.1Kuro
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6)
abnormal B cell physiology J:172608
immune system phenotype J:172608
Stim2tm1Rao/Stim2tm1Rao
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2 * SJL)
abnormal CD4-positive, alpha-beta T cell physiology J:133262
abnormal T-helper 1 physiology J:133262
abnormal T-helper 2 physiology J:133262
decreased interferon-gamma secretion J:133262
decreased interleukin-2 secretion J:133262
decreased interleukin-4 secretion J:133262
Sting1em1Jmin/Sting1+
(involves: C57BL/6N)
abnormal cytokine level J:251372
abnormal spleen morphology J:251372
decreased single-positive T cell number J:251372
enlarged spleen J:251372
increased circulating interleukin-10 level J:251372
increased circulating interleukin-13 level J:251372
increased circulating tumor necrosis factor level J:251372
increased IgM level J:251372
lung inflammation J:251372
Sting1gt/Sting1gt
(C57BL/6-Sting1gt)
abnormal dendritic cell physiology J:201167
abnormal humoral immune response J:201167
abnormal immune cell physiology J:201167
abnormal macrophage physiology J:201167
abnormal plasmacytoid dendritic cell physiology J:201167
abnormal response to infection J:168746
decreased circulating interferon-alpha level J:201167
decreased circulating interferon-beta level J:201167, J:168746
increased susceptibility to Herpesvirales infection J:201167
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:201167
Sting1gt/Sting1gt
(involves: C57BL/6)
immune system phenotype J:265023
increased susceptibility to Retroviridae infection J:265023
Sting1tm1Camb/Sting1tm1Camb
(involves: C57BL/6N)
decreased circulating interferon-beta level J:179270
decreased circulating interleukin-6 level J:179270
immune system phenotype J:179270
Sting1tm1Gnb/Sting1tm1Gnb
(involves: 129P2/OlaHsd * C57BL/6)
abnormal innate immunity J:141011
abnormal susceptibility to Herpesvirales infection J:141011
increased susceptibility to Riboviria infection J:141011
Sting1tm1Gnb/Sting1tm1Gnb
(involves: 129P2/OlaHsd)
abnormal response to infection J:168746
Sting1tm1Gnb/Sting1tm1Gnb
Trex1tm1Tld/Trex1tm1Tld

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:181257
Stip1tm1.2Mamp/Stip1tm1.2Mamp
(involves: C57BL/6)
increased acute inflammation J:201097
Stk3tm1.1Jav/Stk3tm1.1Jav
(involves: 129 * C57BL/6)
immune system phenotype J:153945
Stk3tm1.1Jav/Stk3tm1.1Jav
Stk4tm1Kina/Stk4tm1Kina
Tg(Nkx2-1-cre)2Sand/?

(involves: 129 * C57BL/6)
lung inflammation J:197340
Stk3tm1.1Yy/Stk3tm1Yy
Stk4tm1.1Yy/Stk4tm1.1Yy
Tg(CAG-cre/Esr1*)5Amc/0

(involves: C57BL/6 * CBA)
enlarged spleen J:156541
Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi
(B6.129P2-Stk4Gt(AJ0315)Wtsi)
abnormal memory T cell number J:142674
abnormal T cell differentiation J:142674
decreased CD4-positive, alpha-beta T cell number J:142674
decreased CD8-positive, alpha-beta T cell number J:142674
decreased spleen white pulp amount J:142674
increased interferon-gamma secretion J:142674
increased interleukin-2 secretion J:142674
increased interleukin-4 secretion J:142674
increased T cell apoptosis J:142674
increased T cell proliferation J:142674
Stk4m1Btlr/Stk4m1Btlr
(C57BL/6J-Stk4m1Btlr)
abnormal humoral immune response J:265233
decreased B cell number J:265233
decreased CD4-positive, alpha-beta T cell number J:265233
decreased CD8-positive, alpha-beta T cell number J:265233
decreased IgD level J:265233
decreased single-positive T cell number J:265233
decreased T cell number J:265233
increased IgE level J:265233
increased IgM level J:265233
increased macrophage cell number J:265233
increased neutrophil cell number J:265233
increased NK cell number J:265233
Stk4m2Btlr/Stk4m2Btlr
(C57BL/6J-Stk4m2Btlr)
decreased B-1 B cell number J:265237
decreased B-2 B cell number J:265237
decreased CD4-positive, alpha-beta T cell number J:265237
decreased CD8-positive, alpha-beta T cell number J:265237
decreased CD8-positive, naive alpha-beta T cell number J:265237
decreased IgD level J:265237
decreased single-positive T cell number J:265237
decreased T cell number J:265237
increased B-1b cell number J:265237
increased central memory CD4-positive, alpha-beta T cell number J:265237
increased central memory CD8 positive, alpha-beta T cell number J:265237
increased dendritic cell number J:265237
increased effector memory CD4-positive, alpha-beta T cell number J:265237
increased effector memory CD8-positive, alpha-beta T cell number J:265237
increased IgE level J:265237
increased macrophage cell number J:265237
increased neutrophil cell number J:265237
increased NK cell number J:265237
Stk4m3Btlr/Stk4m3Btlr
(C57BL/6J-Stk4m3Btlr)
decreased CD4-positive, alpha-beta T cell number J:265245
decreased CD8-positive, alpha-beta T cell number J:265245
decreased single-positive T cell number J:265245
decreased T cell number J:265245
Stk4m4Btlr/Stk4m4Btlr
(C57BL/6J-Stk4m4Btlr)
decreased CD11b-high dendritic cell number J:272536
decreased IgD level J:272536
decreased IgG level J:272536
impaired humoral immune response J:272536
increased B-1b cell number J:272536
increased dendritic cell number J:272536
Stk4m5Btlr/Stk4m5Btlr
(C57BL/6J-Stk4m5Btlr)
abnormal CD4-positive T cell differentiation J:272743
abnormal T cell differentiation J:272743
decreased CD4-positive, alpha-beta T cell number J:272743
increased central memory CD4-positive, alpha-beta T cell number J:272743
Stk4tm1.1Kina/Stk4tm1.1Kina
(involves: C57BL/6)
abnormal B cell physiology J:148791
abnormal dendritic cell physiology J:148791
abnormal immune system organ morphology J:148791
abnormal leukocyte adhesion J:148791
abnormal leukocyte migration J:148791
abnormal marginal zone B cell morphology J:148791
abnormal Peyer's patch germinal center morphology J:148791
abnormal Peyer's patch T cell area morphology J:148791
abnormal spleen B cell follicle morphology J:148791
abnormal T cell physiology J:148791
decreased B cell number J:148791
decreased lymphocyte cell number J:148791
decreased marginal zone B cell number J:148791
decreased myeloid dendritic cell number J:148791
decreased spleen B cell follicle size J:148791
decreased T cell number J:148791
increased single-positive T cell number J:148791
increased T cell proliferation J:148791
thymus hyperplasia J:148791
Stk4tm1.1Wtao/Stk4tm1.2Wtao
Tg(Lck-cre)#Zhu/0

(involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL/J)
decreased CD4-positive, alpha-beta T cell number J:152323
decreased CD8-positive, alpha-beta T cell number J:152323
decreased T cell number J:152323
increased single-positive T cell number J:152323
increased thymocyte number J:152323
Stk4tm1.2Wtao/Stk4tm1.2Wtao
(involves: 129S4/SvJaeSor * 129S6/SvEvTac)
abnormal CD4-positive, alpha-beta T cell physiology J:152323
abnormal CD8-positive, alpha-beta T cell physiology J:152323
abnormal T cell physiology J:152323
decreased B cell number J:152323
decreased CD4-positive, alpha-beta T cell number J:152323
decreased CD8-positive, alpha-beta T cell number J:152323
decreased lymphocyte cell number J:152323
increased single-positive T cell number J:152323
increased thymocyte number J:152323
Stk4tm1Dlim/Stk4tm1Dlim
(Not Specified)
abnormal T cell physiology J:155001
decreased T cell number J:155001
Stk10tm1Hkar/Stk10tm1Hkar
(involves: 129S1/Sv)
abnormal T cell physiology J:60738
Stk11tm1.1Mlfr/Stk11+
(involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J)
enlarged spleen J:104347
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(Pdx1-cre)89.1Dam/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N * ICR)
pancreas inflammation J:134078
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(Sprr2f-cre)1Dcas/0

(involves: 129S6/SvEvTac * FVB/N)
peritoneal inflammation J:158190
sepsis J:158190
Stk11tm1.1Sjm/Stk11tm1.1Sjm
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA * SJL)
decreased leukocyte cell number J:165090
thymus hypoplasia J:165090
Stk11tm1Keis/Stk11tm1Keis
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
increased circulating interleukin-10 level J:191723
Stk17btm1Hed/Stk17btm1Hed
(involves: 129X1/SvJ * C57BL/6)
increased T cell proliferation J:94685
Stk17btm1Hed/Stk17btm1Hed
(B6.129X1-Stk17btm1Hed)
abnormal cytokine secretion J:94685
decreased double-positive T cell number J:94685
decreased susceptibility to experimental autoimmune encephalomyelitis J:94685
increased CD4-positive, alpha-beta T cell number J:94685
increased interferon-gamma secretion J:94685
increased interleukin-2 secretion J:94685
increased memory T cell number J:94685
increased T cell proliferation J:94685
increased tumor necrosis factor secretion J:94685
Stk24Gt(AM0826)Wtsi/Stk24Gt(AM0826)Wtsi
(B6.129P2-Stk24Gt(AM0826)Wtsi)
abnormal neutrophil morphology J:256076
abnormal neutrophil physiology J:256076
immune system phenotype J:256076
Stk26tm1b(EUCOMM)Hmgu/Y
(C57BL/6N-Stk26tm1b(EUCOMM)Hmgu/Ccpcz)
increased NK T cell number J:211773
Stk26tm1b(EUCOMM)Hmgu/Stk26tm1b(EUCOMM)Hmgu
(C57BL/6N-Stk26tm1b(EUCOMM)Hmgu/Ccpcz)
decreased monocyte cell number J:211773
Stk36tm1Fjs/Stk36tm1Fjs
(involves: 129S1/Sv * C57BL/6)
rhinitis J:116391
spleen atrophy J:116391
thymus atrophy J:116391
Stk36tm1Lex/Stk36tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased susceptibility to otitis media J:185566
Stk38tm1b(KOMP)Wtsi/Stk38+
(C57BL/6N-Stk38tm1b(KOMP)Wtsi/J)
increased leukocyte cell number J:211773
Stk38tm1Hem/Stk38tm1Hem
(involves: 129P2/Ola * C57BL/6)
abnormal T cell physiology J:185408
decreased thymocyte apoptosis J:185408
Stk38tm1Xen/Stk38tm1Xen
(involves: 129S5/SvEvBrd * C57BL/6)
immune system phenotype J:224932
increased circulating interleukin-6 level J:224932
increased circulating tumor necrosis factor level J:224932
increased interleukin-6 secretion J:224932
increased susceptibility to bacterial infection J:224932
increased susceptibility to bacterial infection induced morbidity/mortality J:224932
increased tumor necrosis factor secretion J:224932
Stoml1em1(IMPC)Tcp/Stoml1em1(IMPC)Tcp
(C57BL/6N-Stoml1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Stoml2tm1Jmad/Stoml2tm1Jmad
Tg(Cd4-cre)1Cwi/0

(B6.Cg-Tg(Cd4-cre)1Cwi Stoml2tm1Jmad)
immune system phenotype J:187226
Stra6tm1Jwu/Stra6tm1Jwu
(B6.129-Stra6tm1Jwu)
immune system phenotype J:211118
Stra6ltm1b(KOMP)Wtsi/Stra6ltm1b(KOMP)Wtsi
(C57BL/6N-Stra6ltm1b(KOMP)Wtsi/Ucd)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased neutrophil cell number J:211773
Stub1tm1Cpat/Stub1tm1Cpat
(involves: 129S/SvEv * C57BL/6)
increased thymocyte apoptosis J:86213
thymus atrophy J:86213
thymus hypoplasia J:86213
Stx2tm1Dcru/Stx2tm1Dcru
(involves: 129X1/SvJ * C57BL/6J)
decreased susceptibility to induced colitis J:110376
Stx3Gt(EUCE320f12)1.1Hmgu/Stx3Gt(EUCE320f12)1.1Hmgu
(B6.129P2(129S4)-Stx3Gt(EUCE320f12)1.1Hmgu)
immune system phenotype J:275367
Stx3Gt(EUCE320f12)1.1Hmgu/Stx3Gt(EUCE320f12)1.1Hmgu
Tg(Cma1-cre)ARoer/0

(B6.Cg-Stx3Gt(EUCE320f12)1.1Hmgu Tg(Cma1-cre)ARoer)
abnormal mast cell degranulation J:275367
decreased mast cell degranulation J:275367
immune system phenotype J:275367
Stx3Gt(EUCE320f12)1.2Hmgu/Stx3+
(B6.129P2(Cg)-Stx3Gt(EUCE320f12)1.2Hmgu)
abnormal mast cell degranulation J:275367
immune system phenotype J:275367
Stx4atm1.1Radac/Stx4atm1.1Radac
(involves: 129S4/SvJaeSor * C57BL/6J)
immune system phenotype J:275367
Stx4atm1.1Radac/Stx4atm1.1Radac
Tg(Cma1-cre)ARoer/0

(involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J)
immune system phenotype J:275367
Stx4atm1.2Radac/Stx4a+
(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J)
immune system phenotype J:275367
Stx7em1(IMPC)Rbrc/Stx7em1(IMPC)Rbrc
(C57BL/6NJcl-Stx7em1(IMPC)Rbrc/Rbrc)
abnormal thymus morphology J:211773
decreased large unstained cell number J:211773
small thymus J:211773
Stx11em1(IMPC)Mbp/Stx11em1(IMPC)Mbp
(C57BL/6N-Stx11em1(IMPC)Mbp/MbpMmucd)
increased lymphocyte cell number J:211773
Stx11tm1.2Ics/Stx11tm1.2Ics
(involves: C57BL/6NTac)
abnormal cytotoxic T cell physiology J:193137
decreased cytotoxic T cell cytolysis J:193137
decreased leukocyte cell number J:193137
decreased neutrophil cell number J:193137
decreased NK cell degranulation J:193137
increased circulating interferon-gamma level J:193137
increased circulating interleukin-1 beta level J:193137
increased circulating interleukin-6 level J:193137
increased circulating tumor necrosis factor level J:193137
increased susceptibility to Riboviria infection J:193137
Stx11tm1Bupa/Stx11tm1Bupa
(B6.129-Stx11tm1Bupa)
abnormal cell-mediated immunity J:191103
abnormal cytokine secretion J:191103
abnormal lymphocyte physiology J:191103
abnormal neutrophil physiology J:191103
impaired natural killer cell mediated cytotoxicity J:191103
increased interferon-gamma secretion J:191103
increased tumor necrosis factor secretion J:191103
Stxbp2tm1Bdic/Stxbp2+
(involves: 129S * C57BL/6)
decreased mast cell degranulation J:188931
decreased susceptibility to type I hypersensitivity reaction J:188931
sty/sty
(Not Specified)
small thymus J:3675
Styk1tm1Twa/Styk1tm1Twa
(C57BL/6N-Styk1tm1Twa)
immune system phenotype J:277150
Styk1tm1Twa/Styk1tm1Twa
(B6J.B6N-Styk1tm1Twa)
immune system phenotype J:277150
Styxl2em1(IMPC)Mbp/Styxl2em1(IMPC)Mbp
(C57BL/6N-Styxl2em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
Sucnr1tm1Dgen/Sucnr1tm1Dgen
(B6.129P2-Sucnr1tm1Dgen)
abnormal dendritic cell physiology J:143337
abnormal interleukin-2 secretion J:143337
abnormal Langerhans cell physiology J:143337
abnormal T cell activation J:143337
decreased T cell proliferation J:143337
increased length of allograft survival J:143337
SucoGt(KST050)Byg/SucoGt(KST050)Byg
(involves: 129P2/OlaHsd * C57BL/6 * CD-1)
abnormal osteoclast physiology J:159823
decreased osteoclast cell number J:159823
Sufutm1b(KOMP)Wtsi/Sufu+
(C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd)
enlarged lymph nodes J:211773
Sugcttm1.2Kald/Sugcttm1.2Kald
(B6.Cg-Sugcttm1.2Kald)
increased macrophage cell number J:293423
kidney inflammation J:293423
white adipose tissue inflammation J:293423
Sugp1em1(IMPC)Mbp/Sugp1+
(C57BL/6NCrl-Sugp1em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Sulf1Gt(OST352220)Lex/Sulf1Gt(OST352220)Lex
(involves: 129S5/SvEvBrd * C57BL/6N)
decreased susceptibility to bacterial infection J:171883
Sult1a1em1(IMPC)Ccpcz/Sult1a1em1(IMPC)Ccpcz
(C57BL/6NCrl-Sult1a1em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Sumf1Gt(RST760)Byg/Sumf1Gt(RST760)Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage morphology J:120146
abnormal microglial cell morphology J:120146
CNS inflammation J:120146
increased macrophage cell number J:120146
Sun1tm1b(EUCOMM)Wtsi/Sun1tm1b(EUCOMM)Wtsi
(C57BL/6N-Sun1tm1b(EUCOMM)Wtsi/Orl)
decreased lymphocyte cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Sun2tm1b(EUCOMM)Hmgu/Sun2tm1b(EUCOMM)Hmgu
(C57BL/6N-Sun2tm1b(EUCOMM)Hmgu/Bay)
increased large unstained cell number J:211773
Sun5em1(IMPC)Mbp/Sun5em1(IMPC)Mbp
(C57BL/6N-Sun5em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Supv3l1tm2.1Jkl/Supv3l1tm2.2Jkl
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N)
abnormal T cell differentiation J:144991
decreased CD4-positive, alpha-beta T cell number J:144991
decreased CD8-positive, alpha-beta T cell number J:144991
decreased double-negative T cell number J:144991
decreased double-positive T cell number J:144991
increased macrophage derived foam cell number J:144991
lung inflammation J:144991
thymus atrophy J:144991
thymus hypoplasia J:144991
Supv3l1tm2Jkl/Supv3l1tm2Jkl
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:144991
decreased CD4-positive, alpha-beta T cell number J:144991
decreased CD8-positive, alpha-beta T cell number J:144991
decreased double-negative T cell number J:144991
decreased double-positive T cell number J:144991
increased macrophage derived foam cell number J:144991
lung inflammation J:144991
thymus atrophy J:144991
thymus hypoplasia J:144991
Supv3l1tm2Jkl/Supv3l1tm2Jkl
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
increased macrophage derived foam cell number J:144991
increased plasma cell number J:144991
interstitial pneumonia J:144991
Susd4tm1Lex/Susd4tm1Lex
(B6.129S5-Susd4tm1Lex)
abnormal complement protein level J:306852
abnormal microglial cell morphology J:306852
increased microglial cell activation J:306852
Susd6tm1b(KOMP)Wtsi/Susd6tm1b(KOMP)Wtsi
(C57BL/6N-Susd6tm1b(KOMP)Wtsi/Bay)
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
enlarged spleen J:211773
increased lymphocyte cell number J:211773
Suv39h1tm1Jnw/Suv39h1tm1Jnw
(involves: 129)
abnormal T-helper 2 physiology J:186702
decreased susceptibility to type I hypersensitivity reaction J:186702
Suz12Plt8/Suz12+
(involves: 129 * C57BL/6)
increased leukocyte cell number J:136262
increased lymphocyte cell number J:136262
Svep1tm1a(EUCOMM)Hmgu/Svep1tm1a(EUCOMM)Hmgu
(involves: C57BL/6N)
abnormal lymphangiogenesis J:244466
abnormal lymphatic vessel morphology J:244466
Swap70tm1Jess/Swap70tm1Jess
(involves: 129T2/SvEms * 129X1/SvJ)
abnormal class switch recombination J:71160
decreased IgE level J:71160
increased autoantibody level J:71160
Swq6C57BL/6J/Swq6CAST/EiJ
(involves: C57BL/6J * CAST/EiJ)
increased spleen weight J:117545
Swq6CAST/EiJ/Swq6CAST/EiJ
(involves: C57BL/6J * CAST/EiJ)
increased spleen weight J:117545
Swqnd1NMRI8/Fbn/?
(involves: DBA/2OlaHsd * NMRI8/Fbn)
decreased spleen weight J:122125
Swqnd2NMRI8/Fbn/?
(involves: DBA/2OlaHsd * NMRI8/Fbn)
decreased spleen weight J:122125
Swrl1NZB/Swrl1NZB
(involves: NZB * SWR)
abnormal type II hypersensitivity reaction J:73097
Swrl1NZB/Swrl1SWR
(involves: NZB * SWR)
abnormal type II hypersensitivity reaction J:73097
Swrl1SWR/Swrl1SWR
(involves: NZB * SWR)
increased IgG3 level J:96263
Swrl2NZB/Swrl2SWR
(involves: NZB * SWR)
glomerulonephritis J:73097
Swrl2SWR/Swrl2SWR
(involves: NZB * SWR)
glomerulonephritis J:73097
increased anti-single stranded DNA antibody level J:96060
Swrl3NZB/Swrl3SWR
(involves: NZB * SWR)
increased anti-double stranded DNA antibody level J:96060
increased anti-histone antibody level J:96060
increased anti-nuclear antigen antibody level J:73097
Swrl3SWR/Swrl3SWR
(involves: NZB * SWR)
increased anti-double stranded DNA antibody level J:96060
increased anti-histone antibody level J:96060
increased anti-nuclear antigen antibody level J:73097
Swt1em1(IMPC)J/Swt1em1(IMPC)J
(C57BL/6NJ-Swt1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Sycntm1Rja/Sycntm1Rja
(involves: 129P2/OlaHsd)
increased susceptibility to induced pancreatitis J:74654
Sykm1Btlr/Sykm1Btlr
(involves: C57BL/6J)
decreased B cell number J:199281
increased neutrophil cell number J:199281
increased tumor necrosis factor secretion J:199281
SykM2Btlr/Syk+
(C57BL/6J-SykM2Btlr)
abnormal NK cell differentiation J:231803
decreased inflammatory response J:231803
SykM2Btlr/SykM2Btlr
(C57BL/6J-SykM2Btlr)
abnormal NK cell differentiation J:231803
decreased inflammatory response J:231803
Syktm1.1(cre)Fkfr/Syktm1.1(cre)Fkfr
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sortm1(EYFP)Cos

(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymphangiogenesis J:159112
decreased leukocyte cell number J:159112
increased leukocyte cell number J:159112
Syktm1.1Nns/Syktm1.1Nns
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/10 * CBA/Ca)
abnormal lymphatic vessel morphology J:181715
Syktm1.1Nns/Syktm1.1Nns
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd)
immune system phenotype J:181715
Syktm1.1Nns/Syktm1.1Nns
Tg(CD2-icre)4Kio/0

(involves: C57BL/10 * CBA/Ca)
immune system phenotype J:181715
Syktm1.1Nns/Syktm1.1Nns
Tg(Pf4-icre)Q3Rsko/0

(involves: C57BL/6)
abnormal lymphatic vessel endothelial cell morphology J:181715
abnormal lymphatic vessel morphology J:181715
Syktm1.1Nns/Syktm1.1Nns
Tg(Tie1-cre)9Ref/0
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/10 * CBA/Ca)
abnormal lymphatic vessel morphology J:181715
Syktm1.1Tara/Syktm1.1Tara
(involves: 129P2/OlaHsd * C57BL/6)
arrested B cell differentiation J:115080
increased B cell proliferation J:114816
Syktm1.2Tara/Syktm1.2Tara
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd)
abnormal B cell morphology J:208904
Syktm1.2Tara/Syktm1.2Tara
Tg(Itgax-cre)1-1Reiz/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:181715
Syktm1Kuro/Syktm1Kuro
Zap70tm1Dlo/Zap70tm1Dlo
Cd79atm1(cre)Reth/?

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal pro-B cell differentiation J:134528
Syktm1Paw/Syktm1Paw
(involves: 129S1/Sv * 129X1/SvJ)
abnormal B cell differentiation J:29797
abnormal lymphangiogenesis J:159112
abnormal lymphatic vessel endothelium morphology J:159112
abnormal lymphatic vessel morphology J:159112
absent pre-B cells J:29797
decreased late pro-B cell number J:29797
enlarged lymphatic vessel J:159112
lymphatic vessel hyperplasia J:159112
Syktm1Tyb/Syktm1.2Tara
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
abnormal neutrophil physiology J:155479
impaired granulocyte bactericidal activity J:155479
Syktm1Tyb/Syktm1.2Tara
Tg(S100A8-cre,-EGFP)1Ilw/0

(involves: 129P2/OlaHsd * 129S2/SvPas * C3H * C57BL/6)
impaired granulocyte bactericidal activity J:155479
Syktm1Tyb/Syktm1Tyb
(involves: 129S2/SvPas * C57BL/6 * DBA/2)
abnormal T cell number J:29796
arrested B cell differentiation J:29796
Syktm1Tyb/Syktm1Tyb
(involves: 129S2/SvPas * C57BL/6)
abnormal osteoclast differentiation J:89583
Syktm1Tyb/Syktm1Tyb
(involves: 129S2/SvPas)
abnormal dendritic cell antigen presentation J:147472
abnormal neutrophil physiology J:155479
decreased tumor necrosis factor secretion J:155479
impaired granulocyte bactericidal activity J:155479
impaired neutrophil phagocytosis J:155479
Syktm1Tyb/Syktm1Tyb
(involves: 129S2/SvPas * C57BL/6J)
abnormal lymphatic vessel morphology J:181715
decreased lymphatic vessel endothelial cell number J:181715
Syktm2.1(ZAP70)Fkfr/Syktm2.1(ZAP70)Fkfr
(B6.129-Syktm2.1(ZAP70)Fkfr)
abnormal B cell physiology J:188422
abnormal neutrophil physiology J:188422
arrested B cell differentiation J:188422
decreased B cell number J:188422
decreased DN1 thymic pro-T cell number J:188422
decreased IgG1 level J:188422
decreased IgG2a level J:188422
decreased IgG2b level J:188422
decreased marginal zone B cell number J:188422
decreased mature B cell number J:188422
decreased transitional stage B cell number J:188422
decreased transitional stage T1 B cell number J:188422
decreased transitional stage T2 B cell number J:188422
glomerulonephritis J:188422
immune system phenotype J:188422
increased anti-insulin autoantibody level J:188422
increased B cell apoptosis J:188422
increased CD4-positive, alpha-beta memory T cell number J:188422
increased CD4-positive, alpha-beta T cell number J:188422
increased CD8-positive, alpha-beta memory T cell number J:188422
increased CD8-positive, alpha-beta T cell number J:188422
increased DN3 thymocyte number J:188422
increased IgM level J:188422
Syne1tm1.1Mcn/Syne1tm1.1Mcn
(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL)
conjunctivitis J:144757
Syngr1em1(IMPC)Ccpcz/Syngr1em1(IMPC)Ccpcz
(C57BL/6NCrl-Syngr1em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Syngr3em1Pave/Syngr3+
Tg(Prnp-MAPT*P301S)PS19Vle/0

(involves: C3H * C57BL/6)
microgliosis J:303506
Synj1tm1b(EUCOMM)Wtsi/Synj1+
(C57BL/6N-Synj1tm1b(EUCOMM)Wtsi/H)
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
increased lymphocyte cell number J:211773
Synpo2tm1b(EUCOMM)Wtsi/Synpo2+
(C57BL/6N-Synpo2tm1b(EUCOMM)Wtsi/Ics)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Syt7tm1Nan/Syt7tm1Nan
(involves: 129S1/Sv * C57BL/6)
increased anti-nuclear antigen antibody level J:85201
increased inflammatory response J:85201
increased susceptibility to autoimmune disorder J:85201
myositis J:85201
Sytl1tm1a(KOMP)Wtsi/Sytl1tm1a(KOMP)Wtsi
(involves: C57BL/6 * C57BL/6N)
decreased CD4-positive, alpha-beta T cell number J:213427
decreased IgG2b level J:213427
decreased mature B cell number J:213427
decreased T cell number J:213427
epididymis inflammation J:213427
increased regulatory T cell number J:213427
meningitis J:213427
Syvn1tm1Tn/Syvn1+
(D1.Cg-Syvn1tm1Tn)
decreased susceptibility to induced arthritis J:86009
tAE5/tAE5
(Not Specified)
abnormal spleen morphology J:83862
abnormal thymus cortex morphology J:83862
abnormal thymus morphology J:83862
decreased spleen white pulp amount J:83862
increased mast cell number J:83862
increased susceptibility to infection J:83862
thymus cortex hypoplasia J:83862
Taar8bem1(IMPC)Mbp/Taar8bem1(IMPC)Mbp
(C57BL/6N-Taar8bem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tab2tm2.1Aki/Tab2tm2.1Aki
Tab3tm1Aki/Tab3tm1Aki
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:195289
abnormal immune serum protein physiology J:195289
decreased B cell proliferation J:195289
decreased B-1a cell number J:195289
decreased circulating interleukin-6 level J:195289
decreased IgD level J:195289
decreased IgE level J:195289
decreased IgG level J:195289
decreased immunoglobulin level J:195289
decreased mature B cell number J:195289
decreased plasma cell number J:195289
increased B cell apoptosis J:195289
Tab2tm2.1Aki/Tab2tm2.1Aki
Tab3tm1Aki/Tab3tm1Aki
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:195289
Tac4tm1Albe/Tac4tm1Albe
(B6.129P2-Tac4tm1Albe)
increased pro-B cell number J:166471
Tacc3tm1Jni/Tacc3tm1Jni
(involves: 129P2/OlaHsd * C57BL/6)
decreased thymocyte number J:74762
small thymus J:74762
Tacr1tm1Nge/Tacr1tm1Nge
(involves: 129S4/SvJae)
abnormal humoral immune response J:35529
Tacr1tm1Nge/Tacr1tm1Nge
(involves: 129S4/SvJae * C57BL)
abnormal mast cell physiology J:84660
Tacr1tm1Sph/Tacr1tm1Sph
(involves: 129P2/OlaHsd * C57BL/6)
decreased inflammatory response J:46629
joint inflammation J:103700
Taf4tm1Idvd/Taf4tm1Idvd
Tg(KRT14-cre/ERT2)1Ipc/0

(involves: C57BL/6 * SJL)
chronic inflammation J:124111
Taf7tm1.1Dss/Taf7tm1.2Dss
Tg(Cd8a*-cre)B8Asin/0

(involves: C57BL/6)
abnormal T cell differentiation J:185745
decreased CD4-positive, alpha-beta T cell number J:185745
decreased CD8-positive, alpha-beta T cell number J:185745
decreased double-positive T cell number J:185745
decreased single-positive T cell number J:185745
decreased T cell number J:185745
decreased T cell proliferation J:185745
decreased thymocyte number J:185745
Taf7tm1.1Dss/Taf7tm1.2Dss
Tg(Lck-cre)1Cwi/0

(involves: C57BL/6)
abnormal T cell differentiation J:185745
abnormal thymus physiology J:185745
decreased CD4-positive, alpha-beta T cell number J:185745
decreased CD8-positive, alpha-beta T cell number J:185745
decreased double-positive T cell number J:185745
decreased thymocyte number J:185745
increased double-negative T cell number J:185745
small thymus J:185745
Taf15em1(IMPC)Mbp/Taf15em1(IMPC)Mbp
(C57BL/6NCrl-Taf15em1(IMPC)Mbp/MbpMmucd)
increased lymphocyte cell number J:211773
Tagap1em1(IMPC)Tcp/Tagap1+
(C57BL/6N-Tagap1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Tagln2em1(IMPC)Tcp/Tagln2em1(IMPC)Tcp
(C57BL/6N-Tagln2em1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
increased neutrophil cell number J:211773
Tagln2tm1Cdj/Tagln2tm1Cdj
(involves: 129S4/SvJae * C57BL/6)
abnormal cytotoxic T cell physiology J:256656
abnormal T cell physiology J:256656
immune system phenotype J:256656
Tagln2tm1Cdj/Tagln2tm1Cdj
Tg(TcraTcrb)425Cbn/0

(involves: 129S4/SvJae * C57BL/6)
abnormal T cell activation J:256656
Tagln2tm1Cdj/Tagln2tm1Cdj
Tg(TcraTcrb)1100Mjb/0

(involves: 129S4/SvJae * C57BL/6)
abnormal T cell activation J:256656
Tal1Hpt/Tal1+
(HPT/Le)
decreased leukocyte cell number J:1780
Tal1tm1Por/Tal1tm1Por
(involves: 129P2/OlaHsd)
increased spleen weight J:139179
Tal1tm3Wehi/Tal1tm2Wehi
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * C57BL/6 * CBA)
abnormal splenic cell ratio J:81826
Tanktm1Aki/Tanktm1Aki
(involves: 129/Sv * C57BL/6)
abnormal dendritic cell physiology J:151757
abnormal macrophage physiology J:151757
abnormal plasmacytoid dendritic cell physiology J:151757
glomerulonephritis J:151757
increased anti-double stranded DNA antibody level J:151757
increased anti-nuclear antigen antibody level J:151757
increased B cell proliferation J:151757
increased IgA level J:151757
increased IgG1 level J:151757
increased IgG2a level J:151757
increased IgG2b level J:151757
increased IgM level J:151757
increased interferon-alpha secretion J:151757
increased interleukin-6 secretion J:151757
increased mature B cell number J:151757
increased plasma cell number J:151757
increased tumor necrosis factor secretion J:151757
liver inflammation J:151757
lung inflammation J:151757
lymph node hyperplasia J:151757
spleen hyperplasia J:151757
Tap1m1Btlr/Tap1m1Btlr
(C57BL/6J-Tap1m1Btlr)
decreased CD8-positive, alpha-beta memory T cell number J:254888
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254888
Tap1m2Btlr/Tap1m2Btlr
(C57BL/6J-Tap1m2Btlr)
decreased CD8-positive, alpha-beta T cell number J:236697
increased susceptibility to Herpesvirales infection J:236697
Tap1rose/Tap1rose
(C57BL/6JAnu-Tap1rose/AnuApb)
decreased CD8-positive, alpha-beta T cell number J:166104
Tap1tm1Arp/Tap1tm1Arp
(involves: 129S2/SvPas * C57BL/6)
abnormal antigen presentation J:122479
abnormal dendritic cell antigen presentation J:112436
abnormal lymphocyte physiology J:122479
absent CD8-positive, alpha-beta T cells J:3524
decreased double-negative T cell number J:3524
decreased level of surface class I molecules J:3524
defective intracellular transport of class I molecules J:3524
Tap1tm1Arp/Tap1tm1Arp
(involves: 129S2/SvPas)
abnormal antigen presentation via MHC class I J:64349
abnormal dendritic cell antigen presentation J:64349
decreased CD8-positive, alpha-beta T cell number J:64177, J:64349
decreased cytotoxic T cell cytolysis J:64349
decreased level of surface class I molecules J:64177, J:64349
defective assembly of class I molecules J:64177
defective intracellular transport of class I molecules J:64177
Tap1tm1Arp/Tap1tm1Arp
(B6.129S2-Tap1tm1Arp/J)
decreased CD8-positive, alpha-beta T cell number J:123934
decreased susceptibility to bacterial infection J:123934
decreased susceptibility to bacterial infection induced morbidity/mortality J:123934
increased T-helper 1 cell number J:123934
Tap1tm1Arp/Tap1tm1Arp
X/Yaa

(BXSB.129S2(B6)-Tap1tm1Arp/Dcr)
increased susceptibility to systemic lupus erythematosus J:179430
Tap1tm1Hpl/Tap1tm1Hpl
(either: (involves: 129S2/SvPas * 129/Ola) or (involves: 129S2/SvPas * FVB))
immune system phenotype J:60782
Tap2jas/Tap2jas
(C57BL/6JSfdAnu-Tap2jas/AnuApb)
absent CD8-positive, alpha-beta T cells J:104190
decreased CD8-positive, alpha-beta T cell number J:166104
Tap2m1Btlr/Tap2m1Btlr
(C57BL/6J-Tap2m1Btlr)
abnormal cytotoxic T cell physiology J:159355
abnormal NK cell physiology J:159355
absent CD8-positive, alpha-beta T cells J:159355
decreased level of surface class I molecules J:159355
defective assembly of class I molecules J:159355
Tap2m2Btlr/Tap2m2Btlr
(C57BL/6J-Tap2m2Btlr)
decreased CD8-positive, alpha-beta T cell number J:217145
increased CD4-positive, alpha-beta T cell number J:217145
Tap2m3Btlr/Tap2m3Btlr
(C57BL/6J-Tap2m3Btlr)
decreased CD8-positive, alpha-beta T cell number J:254929
decreased CD8-positive, naive alpha-beta T cell number J:254929
decreased effector memory CD4-positive, alpha-beta T cell number J:254929
decreased NK T cell number J:254929
increased CD4-positive, alpha-beta T cell number J:254929
increased central memory CD8 positive, alpha-beta T cell number J:254929
Tap2M4Btlr/Tap2M4Btlr
(C57BL/6J-Tap2M4Btlr)
increased CD4-positive, alpha-beta T cell number J:272847
Tapbptm1Gjh/Tapbptm1Gjh
(involves: 129S2/SvPas)
abnormal antigen presentation via MHC class I J:64349
abnormal dendritic cell antigen presentation J:64349
abnormal NK cell physiology J:64349
decreased cytotoxic T cell cytolysis J:64349
decreased level of surface class I molecules J:64349
decreased T cell number J:64349
Tapbptm1Luc/Tapbptm1Luc
(involves: 129S6/SvEvTac * C57BL/6)
abnormal lymphocyte physiology J:122479
Tapbptm1Luc/Tapbptm1Luc
(involves: 129S6/SvEvTac)
abnormal antigen presentation via MHC class I J:64177
abnormal cytotoxic T cell physiology J:64177
decreased CD8-positive, alpha-beta T cell number J:64177
decreased level of surface class I molecules J:64177
defective assembly of class I molecules J:64177
Tapbptm1Luc/Tapbptm1Luc
Tg(TcraTcrb)1100Mjb/?

(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:64177
abnormal CD8-positive, alpha beta T cell morphology J:64177
abnormal negative T cell selection J:64177
abnormal positive T cell selection J:64177
immune system phenotype J:64177
Tapbptm1Luc/Tapbptm1Luc
Tg(TcraTcrb)1100Mjb/?

(involves: 129S6/SvEvTac)
immune system phenotype J:64177
TaprBALB/c/?
(involves: BALB/c * DBA/2)
abnormal inflammatory response J:72894
Tardbptm1.1Neas/Tardbptm1.1Neas
(B6(C3)-Tardbptm1.1Neas)
microgliosis J:283769
Tardbptm2.1Neas/Tardbptm2.1Neas
(B6(C3)-Tardbptm2.1Neas)
microgliosis J:283769
Tarm1tm1Yiw/Tarm1tm1Yiw
(involves: C57BL/6 * C57BL/6NSlc)
abnormal dendritic cell antigen presentation J:301164
abnormal dendritic cell differentiation J:301164
abnormal interleukin-6 secretion J:301164
abnormal lymphocyte physiology J:301164
abnormal tumor necrosis factor secretion J:301164
decreased B cell number J:301164
decreased CD4-positive, alpha-beta T cell number J:301164
decreased dendritic cell number J:301164
decreased IgG2a level J:301164
decreased IgG2b level J:301164
decreased IgG3 level J:301164
decreased interferon-gamma secretion J:301164
decreased interleukin-17 secretion J:301164
decreased susceptibility to induced arthritis J:301164
decreased T cell proliferation J:301164
decreased tumor necrosis factor secretion J:301164
immune system phenotype J:301164
Tars3em1(IMPC)J/Tars3em1(IMPC)J
(C57BL/6NJ-Tars3em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Tas2r131em1(IMPC)Bay/Tas2r131em1(IMPC)Bay
(C57BL/6N-Tas2r131em1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Tas2r139em1(IMPC)Mbp/Tas2r139em1(IMPC)Mbp
(C57BL/6NCrl-Tas2r139em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Tasp1tm1Jjdh/Tasp1tm1Jjdh
Tg(Mx1-cre)1Cgn/?

(involves: 129X1/SvJ * C57BL/6 * CBA)
decreased double-positive T cell number J:112159
decreased thymocyte number J:112159
decreased thymus weight J:112159
Tax1bp1tm1Ktj/Tax1bp1tm1Ktj
(B6.129P2-Tax1bp1tm1Ktj)
abnormal hypersensitivity reaction J:131849
abnormal leukocyte physiology J:131849
abnormal macrophage chemotaxis J:131849
abnormal neutrophil physiology J:131849
abnormal T cell physiology J:131849
cardiovalvulitis J:131849
increased interleukin-1 beta secretion J:131849
increased interleukin-2 secretion J:131849
increased tumor necrosis factor secretion J:131849
skin inflammation J:131849
tb/tb
(Not Specified)
abnormal thymus involution J:12166
Tbatatm1Faf/Tbatatm1Faf
(involves: 129P2/OlaHsd * C57BL/6)
abnormal thymus epithelium morphology J:166065
enlarged thymus J:166065
immune system phenotype J:166065
increased double-negative T cell number J:166065
increased thymocyte number J:166065
thymus hyperplasia J:166065
Tbc1d4tm1.1Arte/Tbc1d4tm1.1Arte
(involves: C57BL/6)
decreased spleen weight J:169477
Tbc1d4tm1b(EUCOMM)Hmgu/Tbc1d4tm1b(EUCOMM)Hmgu
(C57BL/6N-Tbc1d4tm1b(EUCOMM)Hmgu/J)
decreased leukocyte cell number J:211773
Tbc1d8bem1(IMPC)Bay/Y
(C57BL/6N-Tbc1d8bem1(IMPC)Bay/BayMmucd)
decreased spleen weight J:211773
Tbc1d10ctm1.1Psou/Tbc1d10ctm1.2Psou
Cd79atm1(cre)Reth/Cd79a+

(involves: 129S2/SvPas * BALB/c * C57BL/6J)
abnormal B cell physiology J:211913
increased anti-double stranded DNA antibody level J:211913
increased IgG level J:211913
increased IgM level J:211913
increased susceptibility to systemic lupus erythematosus J:211913
Tbc1d10ctm1.1Psou/Tbc1d10ctm1.2Psou
Tg(Lck-cre)#Nik/0

(involves: 129S2/SvPas * C57BL/6 * C57BL/6J * DBA/2)
immune system phenotype J:211913
Tbc1d10ctm1.2Psou/Tbc1d10ctm1.2Psou
(involves: 129S2/SvPas * C57BL/6J)
abnormal B cell physiology J:211913
abnormal response to infection J:211913
abnormal T cell activation J:211913
immune system phenotype J:211913
increased anti-double stranded DNA antibody level J:211913
increased IgG level J:211913
increased susceptibility to systemic lupus erythematosus J:211913
increased T cell proliferation J:211913
Tbc1d23Gt(BA0556)Wtsi/Tbc1d23Gt(BA0556)Wtsi
(B6.129P2-Tbc1d23Gt(BA0556)Wtsi)
abnormal tumor necrosis factor level J:181861
increased circulating interleukin-6 level J:181861
increased circulating tumor necrosis factor level J:181861
increased inflammatory response J:181861
Tbc1d32b2b2284Clo/Tbc1d32b2b2284Clo
(C57BL/6J-Tbc1d32b2b2284Clo)
spleen hypoplasia J:175213
Tbk1M1Btlr/Tbk1+
(involves: C57BL/6J)
abnormal interferon secretion J:188770
abnormal macrophage physiology J:188770
Tbk1tm1.1Lex/Tbk1+
(involves: 129S4/SvJae * 129S5/SvEvBrd)
abnormal inflammatory response J:166476
decreased basophil cell number J:166476
decreased eosinophil cell number J:166476
Tbk1tm1.1Lex/Tbk1tm1.1Lex
(involves: 129S4/SvJae * 129S5/SvEvBrd)
abnormal cytokine level J:166476
abnormal cytokine secretion J:166476
abnormal inflammatory response J:166476
decreased interferon-beta secretion J:166476
decreased NK T cell number J:166476
increased circulating interleukin-1 beta level J:166476
increased circulating interleukin-6 level J:166476
increased circulating interleukin-10 level J:166476
increased circulating tumor necrosis factor level J:166476
increased IgA level J:166476
increased interleukin-6 secretion J:166476
increased monocyte cell number J:166476
increased NK T cell number J:166476
increased spleen weight J:166476
increased susceptibility to bacterial infection induced morbidity/mortality J:166476
increased susceptibility to endotoxin shock J:166476
increased tumor necrosis factor secretion J:166476
lymphoid hyperplasia J:166476
skin inflammation J:166476
Tbk1tm1Aki/Tbk1tm1Aki
Tnftm1Sek/Tnftm1Sek

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal cytotoxic T cell physiology J:132662
decreased cytotoxic T cell cytolysis J:132662
decreased IgG1 level J:132662
decreased IgG2a level J:132662
decreased IgG level J:132662
decreased interferon-gamma secretion J:132662
Tbk1tm1Arte/Tbk1tm1Arte
Cd19tm1(cre)Cgn/Cd19+

(involves: 129/SvEv * 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:188560
abnormal class switch recombination J:188560
increased anti-double stranded DNA antibody level J:188560
increased anti-nuclear antigen antibody level J:188560
increased IgA level J:188560
increased IgM level J:188560
increased mature B cell number J:188560
Tbk1tm1Arte/Tbk1tm1Arte
Map3k14tm1Rds/Map3k14tm1Rds
Cd19tm1(cre)Cgn/Cd19+

(involves: 129/SvEv * 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:188560
abnormal immunoglobulin level J:188560
Tbkbp1tm1Aki/Tbkbp1tm1Aki
(Not Specified)
immune system phenotype J:204786
Tbkbp1tm1b(EUCOMM)Wtsi/Tbkbp1tm1b(EUCOMM)Wtsi
(C57BL/6N-Tbkbp1tm1b(EUCOMM)Wtsi/H)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Tbptm1.1Ees/Tbptm1.1Ees
(B6.129X1(Cg)-Tbptm1.1Ees)
hemophagocytosis J:77714
Tbrg1tm1a(KOMP)Wtsi/Tbrg1tm1a(KOMP)Wtsi
(C57BL/6N-Tbrg1tm1a(KOMP)Wtsi)
enlarged spleen J:225146
increased marginal zone B cell number J:225146
increased spleen white pulp amount J:225146
Tbrs1C57BL/6J/Tbrs1C57BL/6J
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to bacterial infection J:67658
Tbrs2C57BL/6J/Tbrs2C57BL/6J
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to bacterial infection J:67658
Tbrs2C57BL/6J/Tbrs2DBA/2J
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to bacterial infection J:67658
Tbrs3C57BL/6J/Tbrs3C57BL/6J
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to bacterial infection J:67658
Tbrs3C57BL/6J/Tbrs3C57BL/6J
Tbrs4C57BL/6J/Tbrs4C57BL/6J

(involves: C57BL/6J * DBA/2J)
decreased susceptibility to bacterial infection J:83619
Tbrs3C57BL/6J/Tbrs3DBA/2J
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to bacterial infection J:67658
Tbrs4C57BL/6J/Tbrs4C57BL/6J
(involves: C57BL/6J * DBA/2J)
decreased susceptibility to bacterial infection J:83619
Tbs1I/StSnEgYCit/Tbs1A/SnYCit
(involves: A/SnYCit * I/StSnEgYCit)
decreased susceptibility to bacterial infection J:80972
Tbs2I/StSnEgYCit/Tbs2A/SnYCit
(involves: A/SnYCit * I/StSnEgYCit)
decreased susceptibility to bacterial infection J:80972
Tbx1m1H/Tbx1m1H
(involves: C3H/HeH * C57BL/6J)
small thymus J:169366
Tbx1m1Jlk/Tbx1m1Jlk
(129/Sv-Tbx1m1Jlk)
athymia J:146769
Tbx1m1Jlk/Tbx1tm1Bld
(involves: 129)
athymia J:146769
Tbx1tm1.1Dsr/Tbx1tm1.1Dsr
(either: 129/Sv or (involves: 129/Sv * C57BL/6))
athymia J:93588
Tbx1tm1Bem/Tbx1+
(FVB.Cg-Tbx1tm1Bem)
increased susceptibility to otitis media J:91664
Tbx1tm1Bem/Tbx1tm1Bem
(FVB.Cg-Tbx1tm1Bem)
athymia J:91664
thymus hypoplasia J:91664
Tbx1tm1Bld/Tbx1tm1Bld
(involves: 129S7/SvEvBrd)
abnormal lymphangiogenesis J:159824
abnormal lymphatic vessel morphology J:159824
athymia J:146769
lymphangiectasis J:159824
Tbx1tm1Bld/Tbx1tm2.1Bem
Tfap2atm1(cre)Moon/Tfap2a+

(either: (involves: 129/Sv * C57BL/6 * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL))
athymia J:154590
thymus hypoplasia J:154590
Tbx1tm1Bld/Tbx1tm3Bld
Tg(CAG-cre/Esr1*)5Amc/0

(involves: 129S7/SvEvBrd * C57BL/6 * CBA)
abnormal lymphangiogenesis J:159824
abnormal lymphatic vessel morphology J:159824
Tbx1tm1Bld/Tbx1tm3Bld
Tg(Tek-cre)1Ywa/0

(involves: 129S7/SvEvBrd * C57BL/6 * SJL)
abnormal lymphangiogenesis J:159824
abnormal lymphatic vessel morphology J:159824
Tbx1tm1Bld/Tbx1tm5Bld
(involves: 129S7/SvEvBrd * C57BL/6)
athymia J:112457
Tbx1tm1Dsr/Tbx1tm1Dsr
(either: 129/Sv or (involves: 129/Sv * C57BL/6))
athymia J:93588
Tbx1tm1Pa/Tbx1tm1Pa
(either: (involves: 129) or (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * Swiss Webster))
abnormal thymus development J:70730
athymia J:70730
Tbx1tm2.1Bem/Tbx1tm2.2Bem
Foxg1tm1(cre)Skm/Foxg1+

(involves: 129 * C57BL/6J * SJL * Swiss Webster)
athymia J:105980
Tbx3em1(IMPC)Mbp/Tbx3+
(C57BL/6NCrl-Tbx3em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tbx20em1(IMPC)Mbp/Tbx20+
(C57BL/6N-Tbx20em1(IMPC)Mbp/MbpMmucd)
increased neutrophil cell number J:211773
Tbx21duane/Tbx21duane
(C57BL/6-Tbx21duane)
abnormal NK cell differentiation J:154069
absent NK T cells J:154069
decreased NK cell number J:154069
increased NK cell number J:154069
Tbx21m1Btlr/Tbx21m1Btlr
(C57BL/6J-Tbx21m1Btlr)
increased CD8-positive, alpha-beta T cell number J:267478
increased effector memory CD8-positive, alpha-beta T cell number J:267478
increased IgM level J:267478
Tbx21tm1.1(flpe/ERT2)Gmld/Tbx21tm1.1(flpe/ERT2)Gmld
(involves: 129S2/SvPas * C57BL/6)
decreased interferon-gamma secretion J:207104
Tbx21tm1Glm/Tbx21+
(involves: 129S6/SvEvTac * C57BL/6)
abnormal cytokine level J:73833
abnormal interleukin level J:73832
abnormal NK cell physiology J:73833
abnormal tumor necrosis factor level J:73832
decreased T helper 1 cell number J:73833
Tbx21tm1Glm/Tbx21tm1Glm
(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:73833
abnormal cytokine level J:73832
abnormal immunoglobulin level J:73833
abnormal interleukin level J:73832
abnormal NK cell physiology J:73833
abnormal T-helper 1 cell differentiation J:73833
abnormal tumor necrosis factor level J:73832
decreased interferon-gamma secretion J:73833
decreased T helper 1 cell number J:73833
impaired natural killer cell mediated cytotoxicity J:73833
increased natural killer cell mediated cytotoxicity J:73833
increased susceptibility to parasitic infection J:73833
increased T-helper 2 cell number J:73833
respiratory system inflammation J:73832
Tbx21tm1Glm/Tbx21tm1Glm
(C.129S6-Tbx21tm1Glm/J)
abnormal CD4-positive, alpha-beta T cell physiology J:111932
abnormal cytokine secretion J:111932
CNS inflammation J:111932
decreased susceptibility to experimental autoimmune encephalomyelitis J:111932
Tbx21tm1Glm/Tbx21tm1Glm
(B6.129S6-Tbx21tm1Glm)
abnormal CD4-positive T cell differentiation J:143729
Tbx21tm1Glm/Tbx21tm1Glm
(involves: 129S6/SvEvTac)
abnormal cytokine level J:112600
abnormal leukocyte migration J:163822
decreased CD4-positive, alpha-beta T cell number J:163822
decreased memory T cell number J:163822
increased interleukin-17 secretion J:163822
increased susceptibility to induced colitis J:141481
Tbx21tm1Srnr/Tbx21+
(involves: C57BL/6)
absent NK T cells J:112679
decreased NK cell number J:112679
Tbx21tm1Srnr/Tbx21tm1Srnr
(involves: C57BL/6)
abnormal T-helper 1 cell morphology J:112679
decreased NK T cell number J:112679
Tbx21tm2Srnr/Tbx21+
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:174315
increased susceptibility to Riboviria infection J:174315
Tbx21tm2Srnr/Tbx21tm2Srnr
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:174315
immune system phenotype J:137655
increased interleukin-2 secretion J:174315
increased interleukin-17 secretion J:174315
increased susceptibility to Riboviria infection J:174315
increased tumor necrosis factor secretion J:174315
Tbxa2rtm1Cof/Tbxa2rtm1Cof
(either: (involves: 129P2/OlaHsd * C57BL/6 * DBA/2) or (involves: 129P2/OlaHsd * 129S/SvEv))
immune system phenotype J:52125
Tbxa2rtm1Sna/Tbxa2rtm1Sna
(either: (involves: 129/Ola * BALB/c) or (involves: 129/Ola * C57BL/6))
abnormal cervical lymph node morphology J:84085
abnormal immune serum protein physiology J:84085
abnormal immune system organ morphology J:84085
abnormal immune system physiology J:84085
abnormal lymph node morphology J:84085
abnormal type I hypersensitivity reaction J:84085
enlarged lymph nodes J:84085
enlarged spleen J:84085
Tbxa2rtm1Sna/Tbxa2rtm1Sna
(B6.Cg-Tbxa2rtm1Sna)
increased susceptibility to type I hypersensitivity reaction J:197334
Tbxas1tm1Swl/Tbxas1tm1Swl
(involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
decreased inflammatory response J:90922
Tcaf2em1(IMPC)Ccpcz/Tcaf2em1(IMPC)Ccpcz
(C57BL/6NCrl-Tcaf2em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Tcaimtm1b(EUCOMM)Wtsi/Tcaimtm1b(EUCOMM)Wtsi
(C57BL/6N-Tcaimtm1b(EUCOMM)Wtsi/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Tcdel1C57BL/6/Tcdel1NOD/ShiLtDoi
(involves: C57BL/6 * NOD/ShLtDoi * SJL)
decreased double-negative T cell number J:97046
increased double-positive T cell number J:97046
Tcdel1NOD/ShiLtDoi/Tcdel1NOD/ShiLtDoi
(involves: C57BL/6 * NOD/ShLtDoi * SJL)
decreased double-negative T cell number J:97046
increased double-positive T cell number J:97046
Tcdel2C57BL/6/Tcdel2NOD/ShiLtDoi
(involves: C57BL/6 * NOD/ShLtDoi * SJL)
decreased double-negative T cell number J:97046
increased double-positive T cell number J:97046
Tcdel2NOD/ShiLtDoi/Tcdel2NOD/ShiLtDoi
(involves: C57BL/6 * NOD/ShLtDoi * SJL)
decreased double-negative T cell number J:97046
increased double-positive T cell number J:97046
Tcea2em1(IMPC)J/Tcea2em1(IMPC)J
(C57BL/6NJ-Tcea2em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Tceal3em1(IMPC)Tcp/Y
(C57BL/6NCrl-Tceal3em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Tcf3tm1(PBX1)Mlc/Tcf3+
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:226241
abnormal pro-B cell differentiation J:226241
abnormal pro-B cell morphology J:226241
arrested B cell differentiation J:226241
decreased B cell number J:226241
decreased immature B cell number J:226241
enlarged lymph nodes J:226241
enlarged spleen J:226241
increased leukocyte cell number J:226241
Tcf3tm1(PBX1)Mlc/Tcf3+
Cd79atm1(cre)Reth/Cd79a+

(involves: BALB/c * C57BL/6)
arrested B cell differentiation J:226241
decreased B cell number J:226241
decreased immature B cell number J:226241
enlarged lymph nodes J:226241
enlarged spleen J:226241
increased leukocyte cell number J:226241
Tcf3tm1(PBX1)Mlc/Tcf3+
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * C57BL/6J * CBA/J)
arrested B cell differentiation J:226241
decreased B cell number J:226241
decreased immature B cell number J:226241
enlarged lymph nodes J:226241
enlarged spleen J:226241
increased leukocyte cell number J:226241
Tcf3tm1(TCF3/HLF)Homy/Tcf3+
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal B cell differentiation J:160392
increased B cell number J:160392
Tcf3tm1.1Mbu/Tcf3+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:137719
Tcf3tm1Cmu/Tcf3+
(either: 129P2/OlaHsd-Tcf3tm1Cmu or (involves: 129P2/OlaHsd * FVB/N))
decreased B cell number J:67011
Tcf3tm1Cmu/Tcf3tm1Cmu
(either: 129P2/OlaHsd-Tcf3tm1Cmu or (involves: 129P2/OlaHsd * FVB/N))
abnormal immunoglobulin heavy chain V(D)J recombination J:67011
abnormal immunoglobulin V(D)J recombination J:67011
abnormal T cell subpopulation ratio J:67011
decreased B cell number J:67011
decreased lymphocyte cell number J:67011
Tcf3tm1Mbu/Tcf3tm1.2Mbu
Tg(Aicda-cre)9Mbu/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL)
abnormal germinal center B cell morphology J:137719
decreased B cell number J:137719
decreased germinal center B cell number J:137719
immune system phenotype J:137719
Tcf3tm1Mbu/Tcf3tm1.2Mbu
Tg(Fcer2a-cre)5Mbu/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL)
abnormal germinal center B cell morphology J:137719
decreased B cell number J:137719
decreased germinal center B cell number J:137719
immune system phenotype J:137719
increased marginal zone B cell number J:137719
Tcf3tm1Mbu/Tcf3tm1Mbu
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129P2/OlaHsd * C57BL/10 * CBA/Ca)
decreased pro-B cell number J:137719
Tcf3tm1Mbu/Tcf3tm1Mbu
Tg(Ikzf1-Tcfe2a,-GFP)1Mbu/0
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129P2/OlaHsd * C57BL * CBA)
immune system phenotype J:137719
Tcf3tm1Wein/Tcf3+
(either: (involves: 129/Sv * 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J))
decreased B cell number J:22134
Tcf3tm1Wein/Tcf3+
(involves: 129S4/SvJaeSor)
abnormal B cell number J:91042
decreased pre-B cell number J:91042
Tcf3tm1Wein/Tcf3tm1Wein
(either: (involves: 129 * 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J))
abnormal B cell number J:22134
abnormal lymphocyte cell number J:22134
spleen atrophy J:22134
Tcf3tm1Wein/Tcf3tm1Wein
(involves: 129S4/SvJaeSor * C57BL/6)
enlarged thymus J:44278
Tcf3tm1Wein/Tcf3tm3Zhu
(involves: 129/Sv * 129S4/SvJaeSor * C57BL/6)
decreased pro-B cell number J:47671
Tcf3tm1Xhsu/Tcf3tm1Xhsu
(B6.129X1-Tcf3tm1Xhsu)
immune system phenotype J:132669
increased B cell number J:132669
Tcf3tm1Xhsu/Tcf3tm1Xhsu
Tg(Lck-Stat5b*)1Mafa/0

(involves: 129X1/SvJ * C57BL/6 * FVB/N)
increased B cell proliferation J:132669
Tcf3tm1Zhu/Tcf3tm1Zhu
(involves: 129)
decreased B cell number J:47671
Tcf3tm1Zhu/Tcf3tm1Zhu
(involves: 129 * C57BL/6J)
decreased double-positive T cell number J:136143
increased double-negative T cell number J:136143
increased single-positive T cell number J:136143
thymus hypoplasia J:136143
Tcf3tm1Zhu/Tcf3tm2Zhu
(involves: 129 * C57BL/6)
decreased B cell number J:47671
Tcf3tm2Cmu/Tcf3tm2Cmu
(involves: 129P2/OlaHsd)
abnormal lymphopoiesis J:118827
absent pre-B cells J:118827
absent pro-B cells J:118827
decreased dendritic cell number J:118827
decreased NK cell number J:118827
Tcf3tm2Wein/Tcf3tm2Wein
(Not Specified)
abnormal immune system morphology J:47671
Tcf3tm2Zhu/Tcf3tm2Zhu
(involves: 129 * C57BL/6)
decreased pre-B cell number J:47671
decreased pro-B cell number J:47671
Tcf3tm3.1Cmu/Tcf3tm3.1Cmu
(involves: 129S/SvEv * FVB/N)
abnormal B cell differentiation J:153423
abnormal immunoglobulin light chain V-J recombination J:153423
decreased pre-B cell number J:153423
Tcf3tm3Zhu/Tcf3tm3Zhu
(involves: 129/Sv * C57BL/6)
decreased B cell number J:47671
immune system phenotype J:47671
Tcf3tm4.1Cmu/Tcf3tm4.1Cmu
(involves: 129S/SvEv * FVB/N)
abnormal immunoglobulin light chain V-J recombination J:153423
absent B cells J:153423
arrested B cell differentiation J:153423
decreased pro-B cell number J:153423
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Lck-cre)#Zhu/0

(involves: 129S4/SvJae * C57BL/6 * SJL)
immune system phenotype J:75746
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Lck-cre)#Zhu/0
Tg(TcrAND)53Hed/0

(involves: 129S4/SvJae * C57BL/6 * SJL)
immune system phenotype J:75746
Tcf3tm5.1Cmu/Tcf3tm5.1Cmu
(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:183781
Tcf3tm6(Esr1*)Zhu/Tcf3tm6(Esr1*)Zhu
(involves: 129/Sv * C57BL/6)
abnormal immunoglobulin heavy chain V(D)J recombination J:154788
arrested B cell differentiation J:154788
Tcf4tm1.1Hmb/Tcf4+
(involves: 129P2/OlaHsd * C57BL/6J)
increased double-negative T cell number J:136143
Tcf4tm1.1Hmb/Tcf4tm1.1Hmb
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal T cell differentiation J:136143
abnormal T cell physiology J:136143
immune system phenotype J:136143
increased double-negative T cell number J:136143
Tcf4tm1Hmb/Tcf4tm1Zhu
Tg(Kit-cre)143Hmb/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal B cell differentiation J:65236
decreased double-positive T cell number J:65236
decreased thymocyte number J:65236
spleen hypoplasia J:65236
Tcf4tm1Zhu/Tcf4+
Tcf3tm1Wein/Tcf3+

(involves: 129P2/OlaHsd)
decreased pro-B cell number J:43324
Tcf4tm1Zhu/Tcf4tm1Zhu
(involves: 129P2/OlaHsd * C57BL/6)
decreased pro-B cell number J:43324
Tcf7tm1a(EUCOMM)Wtsi/Tcf7tm1a(EUCOMM)Wtsi
(C57BL/6N-Tcf7tm1a(EUCOMM)Wtsi/Ics)
decreased CD4-positive, alpha-beta T cell number J:165965
decreased T cell number J:165965
increased B cell number J:165965
Tcf7tm1Cle/Tcf7tm1Cle
(involves: 129P2/OlaHsd)
abnormal memory T cell physiology J:189838
abnormal T cell differentiation J:23255
decreased CD8-positive, alpha-beta T cell number J:189838
decreased double-positive T cell number J:23255
decreased single-positive T cell number J:23255
decreased T cell number J:23255
increased osteoclast cell number J:98430
thymus cortex hypoplasia J:23255
thymus hypoplasia J:23255
Tcf7tm2Cle/Tcf7tm2Cle
(involves: 129P2/OlaHsd)
decreased double-positive T cell number J:23255
decreased single-positive T cell number J:23255
thymus hypoplasia J:23255
Tcf7l2m1Btlr/Tcf7l2m1Btlr
(C57BL/6J-Tcf7l2m1Btlr)
increased susceptibility to induced colitis J:267536
Tcf12m1Btlr/Tcf12m1Btlr
(C57BL/6J-Tcf12M1Btlr)
increased CD8-positive, alpha-beta T cell number J:267564
Tcf12M2Btlr/Tcf12M2Btlr
(C57BL/6J-Tcf12M2Btlr)
decreased CD4-positive, alpha-beta T cell number J:267666
increased CD8-positive, alpha-beta T cell number J:267666
increased effector memory CD4-positive, alpha-beta T cell number J:267666
Tcf12M3Btlr/Tcf12M3Btlr
(C57BL/6J-Tcf12M3Btlr)
decreased B cell number J:271971
decreased CD4-positive, alpha-beta T cell number J:271971
increased CD8-positive, alpha-beta T cell number J:271971
Tcf12m4Btlr/Tcf12m4Btlr
(C57BL/6J-Tcf12m4Btlr)
abnormal B cell morphology J:271972
abnormal T cell morphology J:271972
decreased CD4-positive, alpha-beta T cell number J:271972
increased CD8-positive, alpha-beta T cell number J:271972
Tcf12tm1Zhu/Tcf12+
Tcf3tm1Wein/Tcf3+

(involves: 129S4/SvJaeSor)
decreased pro-B cell number J:43324
Tcf12tm1Zhu/Tcf12+
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Lck-cre)#Zhu/0

(involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * SJL)
abnormal T cell differentiation J:75746
increased double-negative T cell number J:75746
increased single-positive T cell number J:75746
Tcf12tm1Zhu/Tcf12+
Tcf4tm1Zhu/Tcf4+

(involves: 129P2/OlaHsd * 129S7/SvEvBrd)
decreased pro-B cell number J:43324
Tcf12tm1Zhu/Tcf12tm1Zhu
(involves: 129/Sv * C57BL/6)
decreased pro-B cell number J:43324
Tcf12tm1Zhu/Tcf12tm1Zhu
(involves: 129S7/SvEvBrd)
arrested T cell differentiation J:120411
decreased thymocyte number J:120411
Tcf12tm1Zhu/Tcf12tm1Zhu
(involves: 129S7/SvEvBrd * C57BL/6J)
decreased double-positive T cell number J:136143
increased CD8-positive, alpha-beta T cell number J:136143
increased double-negative T cell number J:136143
thymus hypoplasia J:136143
Tcf12tm1Zhu/Tcf12tm2Zhu
(involves: 129S7/SvEvBrd)
arrested T cell differentiation J:120411
Tcf12tm2Zhu/Tcf12tm2Zhu
(Not Specified)
abnormal B cell differentiation J:120411
abnormal response to transplant J:120411
abnormal T cell differentiation J:120411
absent T cells J:120411
arrested T cell differentiation J:120411
decreased double-positive T cell number J:120411
decreased immature B cell number J:120411
decreased pre-B cell number J:120411
decreased pro-B cell number J:120411
decreased thymocyte number J:120411
increased double-negative T cell number J:120411
thymus hypoplasia J:120411
Tcf12tm2Zhu/Tcf12tm2Zhu
Tg(TcrAND)53Hed/0

(involves: C57BL/6 * SJL)
abnormal CD4-positive, alpha beta T cell morphology J:120411
abnormal T cell subpopulation ratio J:120411
arrested T cell differentiation J:120411
increased T cell number J:120411
Tcf12tm3Zhu/Tcf12tm3Zhu
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJae * C57BL/6 * DBA/2)
abnormal CD8-positive, alpha beta T cell morphology J:129171
abnormal T cell differentiation J:129171
decreased CD4-positive, alpha-beta T cell number J:129171
increased CD8-positive, alpha-beta T cell number J:129171
Tcf12tm3Zhu/Tcf12tm3Zhu
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Lck-cre)#Zhu/0

(involves: 129S4/SvJae * C57BL/6 * SJL/J)
decreased double-positive T cell number J:129570
decreased T cell number J:129570
increased double-negative T cell number J:129570
increased T cell proliferation J:129570
thymus hypoplasia J:129570
Tcf12tm3Zhu/Tcf12tm3Zhu
Tg(Lck-cre)#Zhu/0

(involves: C57BL/6 * SJL/J)
decreased thymocyte number J:129570
increased CD8-positive, alpha-beta T cell number J:129570
Tcf21em1(IMPC)Mbp/Tcf21+
(C57BL/6NCrl-Tcf21em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Tcf21tm1Eno/Tcf21tm1Eno
(involves: 129 * Black Swiss)
abnormal spleen development J:64068
absent spleen J:64068
Tcf21tm2Eno/Tcf21tm2Eno
(involves: 129 * Black Swiss)
abnormal spleen development J:64068
absent spleen J:64068
Tcimtm1Icle/Tcimtm1Icle
(B6.129-Tcimtm1Icle)
abnormal mononuclear cell morphology J:217318
increased eosinophil cell number J:217318
increased leukocyte cell number J:217318
increased lymphocyte cell number J:217318
increased monocyte cell number J:217318
increased neutrophil cell number J:217318
lymphoid hyperplasia J:217318
myeloid hyperplasia J:217318
Tcirg1M1Jeau/Tcirg1+
(either: (involves: C3H/HeJ * C57BL/6) or (involves: C3H/HeJ * C57BL/6 * FVB/N))
abnormal osteoclast morphology J:196503
abnormal osteoclast physiology J:196503
increased osteoclast cell number J:196503
Tcirg1oc/Tcirg1oc
(B6C3Fe a/a-Tcirg1oc/J)
abnormal osteoclast morphology J:7870
Tcirg1tm1.2Ywd/Tcirg1tm1.2Ywd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL)
abnormal macrophage physiology J:150327
Tcirg1tm1Utku/Tcirg1tm1Utku
(involves: 129X1/SvJ * C57BL/6)
abnormal immune serum protein physiology J:92730
abnormal immune system physiology J:92730
abnormal mesenteric lymph node morphology J:92730
abnormal peripheral lymph node morphology J:92730
abnormal Peyer's patch morphology J:92730
abnormal spleen B cell corona morphology J:92730
abnormal spleen morphology J:92730
abnormal spleen periarteriolar lymphoid sheath morphology J:92730
abnormal spleen red pulp morphology J:92730
abnormal spleen white pulp morphology J:92730
decreased B cell number J:92730
decreased lymphocyte cell number J:92730
decreased spleen B cell follicle size J:92730
decreased T cell number J:92730
increased granulocyte number J:92730
increased IgG1 level J:92730
increased IgG2a level J:92730
increased IgM level J:92730
increased immunoglobulin level J:92730
increased spleen germinal center number J:92730
thymus atrophy J:92730
Tcirg1tm1Ypl/Tcirg1tm1Ypl
(involves: 129S4/SvJae * C57BL/6J)
abnormal osteoclast physiology J:58795
Tcpm1BALB/c/Tcpm1BALB/c
(involves: BALB/c * C57BL/10)
abnormal effector T cell morphology J:36255
Tcpm1BALB/c/Tcpm1C57BL/10Sn
(involves: BALB/c * C57BL/10)
abnormal effector T cell morphology J:36255
Tcra-Jtm1Jpdv/Tcra-Jtm1Jpdv
(involves: 129P2/OlaHsd)
abnormal T cell differentiation J:77518
Tcra-Jtm1Kgwa/Tcra-Jtm1Kgwa
Tg(Tcrb2B4)1Mmd/0

(involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6J)
abnormal T cell differentiation J:50143
increased double-positive T cell number J:50143
Tcra-Jtm1Slek/Tcra-Jtm1Slek
(involves: 129P2/OlaHsd)
abnormal T cell differentiation J:101398
decreased double-positive T cell number J:101398
decreased single-positive T cell number J:101398
increased double-negative T cell number J:101398
increased thymocyte number J:101398
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
(B6.129-Tcra-Jtm1Tgi)
decreased activated T cell number J:99107
decreased B cell number J:99107
decreased circulating interleukin-5 level J:121037
decreased IgE level J:121037
decreased IgG level J:99107
decreased susceptibility to induced arthritis J:99107
increased incidence of corneal inflammation J:132503
liver inflammation J:135830
lung inflammation J:121037
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
(involves: 129S1/Sv * 129X1/SvJ)
decreased circulating interferon-gamma level J:155199
decreased interferon-gamma secretion J:155199
decreased susceptibility to bacterial infection J:155199
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
(involves: 129S1/Sv * 129X1/SvJ * BALB/c)
abnormal eosinophil cell number J:84720
abnormal immune serum protein physiology J:84720
abnormal interleukin secretion J:84720
decreased IgE level J:84720
decreased interleukin-4 secretion J:84720
decreased interleukin-13 secretion J:84720
liver inflammation J:105977
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
decreased NK T cell number J:89695
lung inflammation J:89695
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi
(C.129-Tcra-Jtm1Tgi)
abnormal interleukin secretion J:184570
decreased interleukin-5 secretion J:184570
decreased interleukin-9 secretion J:184570
decreased interleukin-10 secretion J:184570
decreased interleukin-13 secretion J:184570
decreased interleukin-17 secretion J:184570
Tcra-Jtm2.3Krg/Tcra-Jtm2.3Krg
(involves: 129S/SvEv * C57BL/6)
abnormal T cell receptor alpha chain V-J recombination J:147326
Tcra-Jtm3.1Krg/Tcra-Jtm3.1Krg
(involves: 129S6/SvEvTac)
abnormal T cell differentiation J:128344
Tcra-Jtm4.1Krg/Tcra-Jtm4.1Krg
(involves: 129S6/SvEvTac)
abnormal T cell receptor alpha chain V-J recombination J:147326
Tcra-Jtm5Krg/Tcra-Jtm5Krg
(involves: 129S6/SvEvTac)
abnormal T cell receptor alpha chain V-J recombination J:147326
TcraLn1Ogu/Tcra+
(involves: 129/Sv * C57BL/6)
abnormal cytokine secretion J:152041
abnormal NK T cell morphology J:152041
abnormal T cell subpopulation ratio J:152041
decreased IgG2a level J:152041
decreased splenocyte number J:152041
decreased thymocyte number J:152041
increased IgG1 level J:152041
increased interferon-gamma secretion J:152041
increased interleukin-2 secretion J:152041
increased interleukin-4 secretion J:152041
increased interleukin-10 secretion J:152041
increased NK T cell number J:152041
TcraLn1Ogu/Tcra+
TcrbLn1Ogu/Tcrb+

(involves: 129/Sv * C57BL/6)
abnormal T cell morphology J:152069
TcraLn2Ogu/Tcra+
TcrbLn2Ogu/Tcrb+

(involves: 129/Sv * C57BL/6)
abnormal T cell morphology J:152069
TcraLn3Jae/Tcra+
(B6.Cg-TcraLn3Jae)
abnormal double-negative T cell morphology J:143006
decreased CD4-positive, alpha-beta T cell number J:143006
decreased double-positive T cell number J:143006
increased CD8-positive, alpha-beta T cell number J:143006
thymus hypoplasia J:143006
TcraLn3Jae/Tcra+
TcrbLn3Jae/Tcrb+

(B6.Cg-TcrbLn3Jae TcraLn3Jae)
abnormal double-negative T cell morphology J:143006
abnormal T cell differentiation J:143006
absent gamma-delta T cells J:143006
decreased CD4-positive, alpha-beta T cell number J:143006
decreased double-positive T cell number J:143006
increased CD8-positive, alpha-beta T cell number J:143006
thymus hypoplasia J:143006
Tcratm1Cgn/Tcratm1Cgn
Tg(Mx1-cre)1Cgn/0

(involves: 129S7/SvEvBrd * C57BL/6 * CBA)
abnormal CD4-positive, alpha beta T cell morphology J:79298
abnormal CD8-positive, alpha beta T cell morphology J:79298
abnormal memory T cell morphology J:79298
abnormal T cell morphology J:79298
Tcratm1Cgn/Tcratm1Cgn
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
immune system phenotype J:201417
Tcratm1Cgn/Tcratm1Mass
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal T cell physiology J:201417
increased T cell number J:201417
Tcratm1Mass/Tcra+
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * DBA/2)
abnormal NK T cell morphology J:201417
decreased NK cell number J:201417
increased NK T cell number J:201417
Tcratm1Mass/Tcra+
Tg(Nes-cre)Wme/0

(involves: C57BL/6 * CBA)
abnormal positive T cell selection J:201417
decreased NK T cell number J:201417
decreased thymocyte number J:201417
increased double-negative T cell number J:201417
Tcratm1Mass/Tcratm1Mass
(involves: C57BL/6)
arrested T cell differentiation J:201417
Tcratm1Mjo/Tcra+
(NOD.129P2-Tcratm1Mjo)
abnormal T cell physiology J:108590
decreased susceptibility to autoimmune diabetes J:108590
Tcratm1Mjo/Tcra+
(SJL.129P2-Tcratm1Mjo)
immune system phenotype J:108590
Tcratm1Mjo/Tcratm1Mjo
(involves: 129P2/OlaHsd * BALB/c)
abnormal immune system organ morphology J:1292
abnormal splenic cell ratio J:1292
abnormal T cell morphology J:1292
abnormal thymus cortex morphology J:1292
absent thymus medulla J:1292
enlarged thymus cortex J:1292
increased activated T cell number J:111129
increased anti-double stranded DNA antibody level J:111129
increased anti-nuclear antigen antibody level J:111129
increased autoantibody level J:111129
increased B cell number J:111129
increased IgE level J:111129
increased IgG1 level J:111129
increased immunoglobulin level J:111129
small Peyer's patches J:1292
Tcratm1Mjo/Tcratm1Mjo
(NOD.129P2-Tcratm1Mjo)
increased activated T cell number J:52940
Tcratm1Mjo/Tcratm1Mjo
(involves: 129P2/OlaHsd)
colitis J:37699
decreased T cell proliferation J:110898
enlarged mesenteric lymph nodes J:110898
enlarged spleen J:110898
increased activated T cell number J:110898
increased gamma-delta T cell number J:110898
increased T cell number J:110898
spleen hyperplasia J:110898
Tcratm1Mjo/Tcratm1Mjo
X/Yaa

(BXSB.129P2(Cg)-Tcratm1Mjo/Theo)
immune system phenotype J:120153
Tcratm1Mom/Tcra/Tcrdtm1.1(Tcra)Rsky
H2b/H2b
Tg(Tcrb)93Vbo/?

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal double-negative T cell morphology J:131357
abnormal double-positive T cell morphology J:81564
abnormal negative T cell selection J:81564
abnormal T cell differentiation J:81564
decreased double-positive T cell number J:131357
decreased thymocyte number J:131357
Tcratm1Mom/Tcra/Tcrdtm1.1(Tcra)Rsky
H2d/H2d
Ptcratm1Vbo/Ptcratm1Vbo
Tg(Tcrb)93Vbo/?

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal T cell differentiation J:131357
decreased thymocyte number J:131357
Tcratm1Mom/Tcratm1Mom
(involves: 129S2/SvPas)
absent T cells J:88620
Tcratm1Mom/Tcratm1Mom
(B6.129S2-Tcratm1Mom)
abnormal response to transplant J:91742
colitis J:135597
increased mature gamma-delta T cell number J:135597
increased susceptibility to bacterial infection J:106241
Tcratm1Mom/Tcratm1Mom
(involves: 129S2/SvPas * C57BL/6)
abnormal response to infection J:119344
arrested T cell differentiation J:3206
colitis J:15221
decreased CD4-positive, alpha-beta T cell number J:3206
decreased CD8-positive, alpha-beta T cell number J:3206
decreased IgG level J:119344
increased gamma-delta intraepithelial T cell number J:15221
Tcratm1Mom/Tcratm1Mom
Tcra-Jtm1Kgwa/Tcra-Jtm1Kgwa

(involves: 129P2/OlaHsd * 129S2/SvPas * C3H/HeJ * C57BL/6J)
increased double-negative T cell number J:50143
Tcratm1Mom/Tcratm1Mom
Tcrbtm1Mom/Tcrbtm1Mom

(involves: 129 * BALB/c * C57BL/6)
arrested T cell differentiation J:3206
decreased double-positive T cell number J:3206
thymus hypoplasia J:3206
Tcratm1Mom/Tcratm1Mom
Tcrgtm1.1Hish/Tcrgtm1.1Hish

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
absent gamma-delta T cells J:135597
colitis J:135597
impaired macrophage chemotaxis J:135597
impaired neutrophil recruitment J:135597
Tcratm1Mom/Tcratm1Mom
Tg(CD19-Tnfsf7)#Rvl/0

(involves: 129P2/OlaHsd * C57BL/6)
absent T cells J:88620
Tcratm1Mom/Tcratm1Mom
Tg(Lck-Akt1*E40K)E-3Pnt/0

(involves: 129S2/SvPas * C3H/He * C57BL/6)
arrested T cell differentiation J:135903
Tcratm1Mom/Tcratm1Mom
Tg(TcraAV19AJ33)1Shima/?

(involves: 129S2/SvPas * C57BL/6)
abnormal NK T cell morphology J:140924
abnormal NK T cell physiology J:140924
Tcratm1Mom/Tcratm1Mom
Trex1tm1Tld/Trex1tm1Tld

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
colitis J:181257
immune system phenotype J:181257
increased inflammatory response J:181257
myositis J:181257
skin inflammation J:181257
Tcratm1Slek/Tcratm1Slek
(Not Specified)
immune system phenotype J:101719
TcrbLn3Jae/Tcrb+
(B6.Cg-TcrbLn3Jae)
abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
Tcrbtm1(Tcrb)Chb/Tcrbtm1(Tcrb)Chb
(Not Specified)
abnormal double-negative T cell morphology J:147947
abnormal T cell morphology J:147947
decreased CD8-positive, alpha-beta T cell number J:147947
increased single-positive T cell number J:147947
Tcrbtm1(Tcrb)Chb/Tcrbtm1Slek
(Not Specified)
abnormal double-negative T cell morphology J:147947
abnormal T cell morphology J:147947
abnormal T cell receptor beta chain V(D)J recombination J:147947
decreased CD8-positive, alpha-beta T cell number J:147947
increased single-positive T cell number J:147947
Tcrbtm1(Tcrb)Fwa/Tcrbtm1(Tcrb)Fwa
(involves: 129)
abnormal T cell receptor beta chain V(D)J recombination J:131995
Tcrbtm1Mom/Tcrb+
Tg(SOD1*G93A)1Gur/0

(B6.Cg-Tcrbtm1Mom Tg(SOD1*G93A)1Gur/J)
abnormal microglial cell physiology J:143173
Tcrbtm1Mom/Tcrbtm1Mom
(involves: 129P2/OlaHsd * BALB/c)
arrested T cell differentiation J:3206
colitis J:15221
decreased CD4-positive, alpha-beta T cell number J:3206
decreased CD8-positive, alpha-beta T cell number J:3206
decreased double-positive T cell number J:3206
thymus hypoplasia J:3206
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom

(FVB.129P2-Tcrbtm1Mom Tcrdtm1Mom)
immune system phenotype J:75915
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom

(involves: 129P2/OlaHsd * C57BL/6)
abnormal response to infection J:119344
decreased IgG level J:119344
immune system phenotype J:126867
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom

(B6.129P2-Tcrbtm1Mom Tcrdtm1Mom/J)
abnormal transitional stage B cell morphology J:187766
decreased autoantibody level J:187766
decreased IgE level J:125656
decreased IgG1 level J:125656
decreased IgG level J:125656, J:187766
decreased plasma cell number J:187766
decreased T cell number J:187766
increased B cell number J:187766
increased follicular B cell number J:187766
increased IgM level J:187766
increased immature B cell number J:187766
increased marginal zone B cell number J:187766
increased mature B cell number J:187766
increased transitional stage T2 B cell number J:187766
increased transitional stage T3 B cell number J:187766
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom

(involves: 129 * BALB/c * C57BL/6)
absent CD4-positive, alpha-beta T cells J:3206
absent CD8-positive, alpha-beta T cells J:3206
arrested T cell differentiation J:3206
colitis J:15221
decreased double-positive T cell number J:3206
thymus hypoplasia J:3206
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom

(involves: 129P2/OlaHsd)
decreased IgA level J:97824
decreased lymphocyte cell number J:97824
immune system phenotype J:97824
increased T cell number J:97824
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+

(B6.129P2-Tcrbtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg Tcrdtm1Mom)
increased anti-double stranded DNA antibody level J:142389
increased marginal zone B cell number J:142389
spleen hypoplasia J:142389
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix

(B6.129-Tcrbtm1Mom Traf3ip2tm1.1Lix Tcrdtm1Mom)
abnormal transitional stage B cell morphology J:187766
decreased IgG level J:187766
decreased T cell number J:187766
immune system phenotype J:187766
increased anti-chromatin antibody level J:187766
increased anti-double stranded DNA antibody level J:187766
increased anti-histone antibody level J:187766
increased autoantibody level J:187766
increased IgM level J:187766
increased immature B cell number J:187766
increased marginal zone B cell number J:187766
Tcrbtm1Mom/Tcrbtm1Mom
Tg(H2-K-Cd86)7All/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal B cell differentiation J:112475
abnormal B cell morphology J:112475
decreased B cell number J:112475
Tcrbtm1Mom/Tcrbtm1Mom
Tg(KRT5-rtTA)1Glk/0
Tg(tetO/CMV-Tslp)#Sfz/0

(involves: 129P2/OlaHsd * C3H * C57BL/6 * FVB/N)
decreased IgE level J:100506
skin inflammation J:100506
Tcrbtm1Slek/Tcrbtm1Slek
(Not Specified)
immune system phenotype J:119552
Tcrbtm1Slek/Tcrbtm5Slek
(Not Specified)
abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm1Slek/Tcrbtm6Slek
(Not Specified)
abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm2(Tcrb)Fwa/Tcrbtm3Slek
(involves: 129)
abnormal T cell receptor beta chain V(D)J recombination J:132446
Tcrbtm2Slek/Tcrbtm2Slek
(Not Specified)
arrested T cell differentiation J:119552
decreased T cell number J:119552
Tcrbtm2Slek/Tcrbtm2Slek
Trbv13-2tm1(CD2)Zhu/Trbv13-2tm1(CD2)Zhu

(involves: 129 * C57BL/6)
abnormal T cell differentiation J:121608
Tcrbtm3.1Che/Tcrbtm3.1Che
(involves: 129S4/SvJae)
immune system phenotype J:120387
Tcrbtm3Che/Tcrbtm3Che
(involves: 129S4/SvJae)
immune system phenotype J:120387
Tcrbtm3Slek/Tcrbtm3Slek
(Not Specified)
arrested T cell differentiation J:119552
decreased T cell number J:119552
Tcrbtm4Slek/Tcrbtm4Slek
(Not Specified)
immune system phenotype J:119552
Tcrbtm5Slek/Tcrbtm5Slek
(Not Specified)
abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm6Slek/Tcrbtm6Slek
(Not Specified)
abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm7Slek/Tcrbtm7Slek
(Not Specified)
abnormal T cell receptor beta chain V(D)J recombination J:143738
Tcrbtm8.1Slek/Tcrbtm8.1Slek
(Not Specified)
immune system phenotype J:176070
Tcrbtm9.1Slek/Tcrbtm9.1Slek
(Not Specified)
immune system phenotype J:176070
Tcrd-V1tm1Kjk/Tcrd-V1tm1Kjk
(involves: 129P2/OlaHsd * C57BL/6)
abnormal gamma-delta T cell differentiation J:64863
abnormal mature gamma-delta T cell morphology J:64863
abnormal T cell receptor delta chain V(D)J recombination J:64863
decreased gamma-delta intraepithelial T cell number J:64863
Tcrd-V1tm1Kjk/Tcrd-V1tm1Kjk
(B6.129P2-Tcrd-V1tm1Kjk)
abnormal T cell receptor delta chain V(D)J recombination J:128525
decreased gamma-delta intraepithelial T cell number J:128525
Tcrdtm1Mom/Tcrdtm1Mom
(FVB.129P2-Tcrdtm1Mom)
dermatitis J:75915
increased susceptibility to type IV hypersensitivity reaction J:75915
Tcrdtm1Mom/Tcrdtm1Mom
(NOD.129P2-Tcrdtm1Mom)
dermatitis J:75915
Tcrdtm1Mom/Tcrdtm1Mom
(B6.129P2-Tcrdtm1Mom)
immune system phenotype J:75915
Tcrdtm1Mom/Tcrdtm1Mom
(either: (involves: 129P2/OlaHsd * BALB/cJ) or (involves: 129P2/OlaHsd * C57BL/6))
abnormal gamma-delta T cell differentiation J:3865
absent gamma-delta T cells J:3865
Tcrdtm1Mom/Tcrdtm1Mom
Tcrgtm2.1Dhr/Tcrgtm2.1Dhr

(involves: 129 * C57BL/6)
abnormal T cell receptor gamma chain V-J recombination J:75624
Tcrdtm1Mom/Tcrdtm1Mom
Tnftm2Gkl/Tnf+

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J)
small intestinal inflammation J:108572
Tcrgtm1.1Dhr/Tcrgtm1.1Dhr
(involves: 129)
abnormal T cell receptor gamma chain V-J recombination J:133974
Tcrgtm1.1Hish/Tcrgtm1.1Hish
(involves: 129P2/OlaHsd * C57BL/6)
absent gamma-delta T cells J:135597
Tcrgtm1Dhr/Tcrgtm1Dhr
(involves: 129)
abnormal T cell receptor gamma chain V-J recombination J:133974
Tcrgtm1Iku/Tcrgtm1Iku
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:39791
Tcrgtm1Scar/Tcrgtm1Scar
(B6.Cg-Tcrgtm1Scar)
abnormal immune system organ morphology J:105477
enlarged spleen J:105477
enlarged thymus J:105477
impaired granulocyte bactericidal activity J:105477
increased macrophage cell number J:105477
increased T cell number J:105477
spleen hyperplasia J:105477
thymus hyperplasia J:105477
Tcrgtm2.1Dhr/Tcrgtm2.1Dhr
(involves: 129S4/SvJae * C57BL/6)
abnormal gamma-delta T cell differentiation J:75624
abnormal T cell receptor gamma chain V-J recombination J:75624
Tdp1em1(IMPC)Tcp/Tdp1em1(IMPC)Tcp
(C57BL/6NCrl-Tdp1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Tdp2tm1.1Huy/Tdp2tm1.1Huy
(involves: 129P2/OlaHsd * CD-1)
abnormal immature B cell morphology J:195301
abnormal immune system organ morphology J:195301
abnormal lymphopoiesis J:195301
decreased double-positive T cell number J:195301
spleen atrophy J:195301
thymus atrophy J:195301
Tdrd3Gt(RRK474)Byg/Tdrd3Gt(RRK474)Byg
(involves: 129P2/OlaHsd)
abnormal B cell differentiation J:210647
abnormal B cell physiology J:210647
Tdrd7nmf166/Tdrd7nmf166
(involves: C3H * C57BL/6J)
uveitis J:169836
Tectm1Welm/Tectm1Welm
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:66080
Tecpr1tm1Chsa/Tecpr1tm1Chsa
(involves: 129S4/SvJae)
abnormal susceptibility to infection J:198333
Tedc1em1(IMPC)Tcp/Tedc1+
(C57BL/6NCrl-Tedc1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Teddm1aem1(IMPC)Tcp/Teddm1aem1(IMPC)Tcp
(C57BL/6N-Teddm1aem1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
Tekt1em1(IMPC)Ccpcz/Tekt1em1(IMPC)Ccpcz
(C57BL/6NCrl-Tekt1em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
small lymph nodes J:211773
Tenm4em1(IMPC)Tcp/Tenm4em1(IMPC)Tcp
(C57BL/6NCrl-Tenm4em1(IMPC)Tcp/Tcp)
decreased spleen weight J:211773
Tent5aem1(IMPC)Ccpcz/Tent5aem1(IMPC)Ccpcz
(C57BL/6N-Tent5aem1(IMPC)Ccpcz/Ccpcz)
decreased Ly6C-positive mature NK cell number J:211773
decreased lymphocyte cell number J:211773
increased granulocyte number J:211773
increased leukocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Tent5cem1Adki/Tent5cem1Adki
(involves: C57BL/6J * CBA)
decreased B cell proliferation J:252302
Tent5ctm1b(KOMP)Wtsi/Tent5ctm1b(KOMP)Wtsi
(C57BL/6N-Tent5ctm1b(KOMP)Wtsi/Wtsi)
absent connection between subcutaneous lymph vessels and lymph sac J:239583
blood in lymph vessels J:239583
Terb1tm1b(KOMP)Mbp/Terb1+
(C57BL/6N-Terb1tm1b(KOMP)Mbp/Ucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Terctm1Rdp/Terctm1Rdp
(involves: 129/Sv * C57BL/6J * SJL)
decreased B cell proliferation J:60223
decreased spleen B cell follicle number J:60223
decreased spleen germinal center number J:60223
decreased T cell proliferation J:60223
increased B cell apoptosis J:60223
Terf1tm1.1Blas/Terf1tm1.1Blas
Tg(KRT5-cre)1Tak/0

(involves: 129 * C3H * C57BL/6 * SJL)
skin inflammation J:152077
Terf2ipGt(XD108)Byg/Terf2ip+
(involves: 129P2/OlaHsd * C57BL/6)
decreased susceptibility to bacterial infection induced morbidity/mortality J:163158
decreased susceptibility to endotoxin shock J:163158
Terttm2.1Rdp/Terttm2.1Rdp
(involves: C57BL/6)
decreased spleen weight J:167227
spleen atrophy J:167227
Tespa1tm1Smoc/Tespa1tm1Smoc
(B6.129-Tespa1tmSmoc)
abnormal T cell differentiation J:186446
abnormal thymus morphology J:186446
decreased CD4-positive, alpha-beta T cell number J:186446
decreased CD8-positive, alpha-beta T cell number J:186446
decreased interferon-gamma secretion J:186446
decreased interleukin-2 secretion J:186446
decreased regulatory T cell number J:186446
decreased T cell number J:186446
decreased T cell proliferation J:186446
increased memory T cell number J:186446
increased T cell proliferation J:186446
small thymus medulla J:186446
Tespa1tm1Smoc/Tespa1tm1Smoc
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129 * C57BL/6 * DBA/2J)
decreased CD8-positive, alpha-beta T cell number J:186446
Tespa1tm1Smoc/Tespa1tm1Smoc
Tg(TcraTcrb)425Cbn/0

(B6.Cg-Tespa1tm1Smoc Tg(TcraTcrb)425Cbn)
abnormal T cell differentiation J:186446
decreased CD4-positive, alpha-beta T cell number J:186446
decreased CD8-positive, alpha-beta T cell number J:186446
Tespa1tm1Smoc/Tespa1tm1Smoc
Tg(TcraTcrb)1100Mjb/0

(B6.Cg-Tespa1tm1Smoc Tg(TcraTcrb)1100Mjb)
abnormal T cell differentiation J:186446
decreased CD4-positive, alpha-beta T cell number J:186446
decreased CD8-positive, alpha-beta T cell number J:186446
Tet1tm1.1Jae/Tet1tm1.1Jae
(involves: 129S4/SvJae * C57BL/6)
decreased neutrophil cell number J:175858
Tet1tm1.2Jae/Tet1tm1.2Jae
Tet2tm1.1Iaai/Tet2+
Tet3tm1.1Yzhg/Tet3tm1.1Yzhg
Tg(Rorc-cre)1Litt/0

(involves: 129 * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB)
decreased effector memory T-helper cell number J:333574
immune system phenotype J:333574
Tet1tm1.2Jae/Tet1tm1.2Jae
Tet2tm1.1Iaai/Tet2tm1.1Iaai
Tet3tm1.1Yzhg/Tet3tm1.1Yzhg
Tg(Rorc-cre)1Litt/0

(involves: 129 * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB)
enlarged lymph nodes J:333574
enlarged spleen J:333574
increased susceptibility to autoimmune disorder J:333574
Tet2Gt(AN0709)Wtsi/Tet2+
(B6.129P2-Tet2Gt(AN0709)Wtsi)
abnormal monocyte differentiation J:174052
abnormal spleen morphology J:174052
enlarged spleen J:174052
increased B cell number J:174052
increased leukocyte cell number J:174052
increased monocyte cell number J:174052
liver inflammation J:174052
Tet2Gt(AN0709)Wtsi/Tet2Gt(AN0709)Wtsi
(B6.129P2-Tet2Gt(AN0709)Wtsi)
abnormal monocyte differentiation J:174052
abnormal spleen morphology J:174052
decreased pre-B cell number J:174052
decreased pro-B cell number J:174052
enlarged spleen J:174052
increased B cell number J:174052
increased DN1 thymic pro-T cell number J:174052
increased double-negative T cell number J:174052
increased leukocyte cell number J:174052
increased monocyte cell number J:174052
liver inflammation J:174052
Tet2tm1.1Iaai/Tet2+
Tg(VAV1-cre)1Graf/0

(involves: 129S/SvEv * C57BL/6)
increased leukocyte cell number J:174053
increased monocyte cell number J:174053
Tet2tm1.1Iaai/Tet2tm1.1Iaai
Tg(Mx1-cre)1Cgn/0

(involves: 129S/SvEv * C57BL/6 * CBA)
abnormal myelopoiesis J:234976
decreased B cell number J:234976
enlarged spleen J:234976
increased granulocyte number J:234976
Tet2tm1.1Iaai/Tet2tm1.1Iaai
Tg(VAV1-cre)1Graf/0

(involves: 129S/SvEv * C57BL/6)
abnormal myeloid leukocyte morphology J:174053
enlarged spleen J:174053
increased leukocyte cell number J:174053
increased monocyte cell number J:174053
increased spleen weight J:174053
myeloid hyperplasia J:174053
Tet2tm1.1Mjxu/Tet2+
(involves: 129 * C57BL/6)
enlarged spleen J:178415
increased leukocyte cell number J:178415
increased monocyte cell number J:178415
myeloid hyperplasia J:178415
Tet2tm1.1Mjxu/Tet2tm1.1Mjxu
(involves: 129 * C57BL/6)
enlarged spleen J:178415
increased leukocyte cell number J:178415
increased monocyte cell number J:178415
increased neutrophil cell number J:178415
myeloid hyperplasia J:178415
Tet2tm1.2Rao/Tet2tm1.2Rao
(involves: C57BL/6NTac)
abnormal myelopoiesis J:175222
increased splenocyte number J:175222
Tet2tm1Ics/Tet2tm1Ics
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal spleen morphology J:174052
decreased pre-B cell number J:174052
decreased pro-B cell number J:174052
enlarged spleen J:174052
increased B cell number J:174052
increased DN1 thymic pro-T cell number J:174052
increased double-negative T cell number J:174052
increased leukocyte cell number J:174052
increased monocyte cell number J:174052
increased spleen red pulp amount J:174052
Tex2tm1.1(KOMP)Vlcg/Tex2+
(C57BL/6N-Tex2tm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Tex29tm1.1(KOMP)Vlcg/Tex29tm1.1(KOMP)Vlcg
(C57BL/6N-Tex29tm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Tex261tm1b(EUCOMM)Wtsi/Tex261tm1b(EUCOMM)Wtsi
(C57BL/6N-Tex261tm1b(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Tfap4tm1.1(KOMP)Vlcg/Tfap4tm1.1(KOMP)Vlcg
(C57BL/6N-Tfap4tm1.1(KOMP)Vlcg/Ucd)
decreased thymus weight J:211773
Tfap4tm1.1Litt/Tfap4tm1.1Litt
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
abnormal T cell differentiation J:176461
immune system phenotype J:176461
Tfebem1Xinli/Tfebem1Xinli
(involves: C57BL/6J)
increased susceptibility to bacterial infection induced morbidity/mortality J:342735
Tff2tm1Blin/Tff2tm1Blin
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal adaptive immunity J:105277
abnormal innate immunity J:105277
Tff3tm1Dkpy/Tff3tm1Dkpy
(involves: 129S4/SvJae)
increased susceptibility to induced colitis J:35882
Tfpi2tm1Dgen/Tfpi2tm1Dgen
(involves: 129P2/OlaHsd * C57BL/6J)
immune system phenotype J:301794
increased circulating interleukin-6 level J:301794
increased circulating interleukin-10 level J:301794
increased interleukin-10 secretion J:301794
increased susceptibility to bacterial infection J:301794
increased susceptibility to bacterial infection induced morbidity/mortality J:301794
Tfpitm1Gjb/Tfpitm1Gjb
(involves: 129)
abnormal acute phase protein level J:51137
Tfr2tm1.1Anro/Tfr2tm1.1Anro
(129.Cg-Tfr2tm1.1Anro)
increased spleen iron level J:160785
Tfr2tm1.1Nsub/Tfr2tm1.1Nsub
(involves: 129T2/SvEms * C57BL/6)
decreased spleen iron level J:114330
Tfr2tm1.1Nsub/Tfr2tm1.1Nsub
(involves: 129T2/SvEms)
increased spleen iron level J:160785
Tfr2tm1Slu/Tfr2tm1Slu
(involves: 129X1/SvJ * C57BL/6J)
decreased spleen iron level J:78360
Tfrcem1(IMPC)H/Tfrc+
(C57BL/6N-Tfrcem1(IMPC)H/H)
increased large unstained cell number J:211773
Tfrctm1Nca/Tfrc+
(either: (involves: 129S4/SvJae * 129S6/SvEvTac) or (involves: 129S4/SvJae * C57BL/6))
decreased spleen iron level J:54107
Tg(Ace2-ACE2)1Cqin/0
(involves: ICR)
alveolitis J:141460
increased susceptibility to Coronaviridae infection J:141460, J:287631, J:288244
interstitial pneumonia J:141460, J:287631
lymph node hemorrhage J:141460
lymph node necrosis J:287631
pyelitis J:141460
submandibular gland inflammation J:141460
Tg(Acp5-Adam8)#Rood/0
(involves: BALB/c * C57BL/6)
abnormal osteoclast differentiation J:172936
abnormal osteoclast morphology J:172936
increased osteoclast cell number J:172936
Tg(Acp5-Selenow)#Djeo/0
(involves: FVB/N)
abnormal osteoclast differentiation J:317012
increased osteoclast cell number J:317012
Tg(ACTA1-Il15)10941Lsq/0
(involves: C3H * C57BL/6)
abnormal interleukin level J:145611
Tg(ACTA1-Il15*)11650Lsq/0
(involves: C3H * C57BL/6)
abnormal interleukin level J:145611
increased circulating interleukin-15 level J:145611
Tg(Acta2-cre/ERT2)#Pcn/0
Tgfbr2tm1Karl/Tgfbr2tm1Karl
Tg(H2-K-Fosl2,-EGFP)13Wag/0

(B6.Cg-Tgfbr2tm1Karl Tg(Acta2-cre/ERT2)#Pcn Tg(H2-K-Fosl2,-EGFP)13Wag)
lung inflammation J:238723
Tg(Acta2-RAC1*G12V)33Pjgc/Tg(Acta2-RAC1*G12V)33Pjgc
(involves: C57BL/6 * FVB/N)
abnormal chemokine secretion J:150015
increased interleukin-6 secretion J:150015
increased tumor necrosis factor secretion J:150015
Tg(ACTB-eGFP,-RAMP1)#Afru/0
Tg(Nes-cre)1Kln/0

(involves: C57BL/6J * SJL/J)
increased inflammatory response J:120077
Tg(ACTB-Eif4e)#Ppp/0
Tg(IghMyc)22Bri/0

(involves: C57BL * SJL)
decreased B cell apoptosis J:89878
Tg(ACTB-Fpr2)#Jimw/0
(involves: FVB)
abnormal dendritic cell physiology J:160074
respiratory system inflammation J:160074
Tg(ACTB-Mgat3)2Nta/0
(involves: C57BL/6 * DBA/2)
decreased leukocyte cell number J:80227
decreased lymphocyte cell number J:80227
decreased neutrophil cell number J:80227
decreased spleen B cell follicle number J:80227
spleen atrophy J:80227
Tg(ACTB-TNFRSF6B)754Jwu/?
(B6.Cg-Tg(Actb-TNFRSF6B)754Jwu)
abnormal CD4-positive, alpha beta T cell morphology J:148162
abnormal type IV hypersensitivity reaction J:148162
decreased leukocyte cell number J:148162
enlarged lymph nodes J:148162
enlarged spleen J:148162
increased anti-double stranded DNA antibody level J:148162
increased autoantibody level J:148162
increased B-1a cell number J:148162
increased IgE level J:148162
increased IgG1 level J:148162
increased IgG2b level J:148162
increased interleukin-4 secretion J:148162
Tg(Actb-Tnfsf4)1Nish/0
(B6.D2-Tg(Actb-Tnfsf4)1Nish)
abnormal cytokine secretion J:80214
increased susceptibility to type IV hypersensitivity reaction J:80214
increased T cell proliferation J:80214
Tg(Adipoq-Apol6)#Hsul/0
(C57BL/6J-Tg(Adipoq-Apol6)#Hsul)
white adipose tissue inflammation J:344362
Tg(Adipoq-cre)1Evdr/0
Tg(CAG-Jmjd8)#Kaso/0

(involves: C57BL/6 * FVB/NJ)
white adipose tissue inflammation J:319518
Tg(AGER)#Eca/0
(C57BL/6J-Tg(AGER)#Eca)
lung inflammation J:205092
Tg(AGT)2-5Afu/0
(involves: C57BL/6)
heart inflammation J:194606
Tg(Alb1-GP33/H2-Kb)1Hpi/0
(B6.Cg-Tg(Alb1-GP33/H2-Kb)1Hpi)
abnormal cytotoxic T cell physiology J:162605
decreased cytotoxic T cell cytolysis J:162605
Tg(Alb1-GP33/H2-Kb)1Hpi/0
Tg(Alb1-HBV)66Bri/0

(involves: C57BL/6 * C57BL/10 * DBA/2)
liver inflammation J:162605
Tg(Alb1-GP33/H2-Kb)1Hpi/0
Tg(Alb1-HBV)66Bri/0
Tg(TcrLCMV)318Sdz/0

(involves: C57BL/6 * C57BL/10 * DBA/2)
liver inflammation J:162605
Tg(Alb1-GP33/H2-Kb)1Hpi/0
Tg(TcrLCMV)318Sdz/0

(involves: C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:162605
Tg(Alb1-Myc)#Sst/0
Tg(MtTGFA)Lmb/0

(involves: C57BL/6 * CBA * CD-1)
decreased NK cell number J:176432
increased NK T cell number J:176432
Tg(Alb1-Ren)1Unc/0
(involves: 129S6/SvEvTac * C57BL/6)
kidney inflammation J:89252
Tg(Alb1-Ren)2Unc/0
(involves: 129S6/SvEvTac * C57BL/6)
kidney inflammation J:89252
Tg(Alb1HBV)44Bri/0
(C57BL/6J-Tg(Alb1HBV)44Bri/J)
liver inflammation J:223921
Tg(Alb-PDGFC)#Jcam/0
(involves: C57BL/6)
chronic liver inflammation J:211984
enlarged spleen J:211984
increased circulating interleukin-6 level J:211984
Tg(Alb-PLG)1Dgi/0
(involves: C57BL/6 * C57BL/6J * SJL)
increased susceptibility to bacterial infection J:120780
Tg(Alb-SND1)3aDsar/0
(involves: C57BL/6 * CBA)
chronic liver inflammation J:242582
Tg(Alb-TAg)#Arnd/0
((C3Fe.Cg-Tg(Alb-TAg)#Arnd x C57BL/6N)F1)
abnormal immune system physiology J:171880
Tg(Amy1TAg)501Knw/0
(involves: C57BL/6)
abnormal CD8-positive, alpha-beta T cell physiology J:84288
Tg(ANPEP)270Mmul/Tg(ANPEP)270Mmul
(involves: ICR)
immune system phenotype J:99728
Tg(ANPEP)861Mmul/Tg(ANPEP)861Mmul
(involves: ICR)
immune system phenotype J:99728
Tg(ANX6)2Agh/0
(FVB/N-Tg(ANX6)2Agh)
myocarditis J:92579
thymus cortex hypoplasia J:92579
Tg(aP2-SREBF1c)9884Reh/0
(involves: C57BL/6J * SJL)
abnormal abdominal lymph node morphology J:50770
decreased interleukin-6 secretion J:249664
decreased tumor necrosis factor secretion J:249664
enlarged spleen J:50770
liver inflammation J:249664
Tg(APCS-Ifng)5Imeg/0
(involves: C57BL/6 * DBA/2)
abnormal cytokine level J:135124
chronic liver inflammation J:135124
increased circulating interleukin-12 level J:135124
liver inflammation J:16979
myocarditis J:135124
pancreas inflammation J:135124
Tg(APCS-Tnfsf11*)#aKhs/0
(C57BL/6J-Tg(APCS-Tnfsf11*)#aKhs)
abnormal osteoclast morphology J:264357
enlarged thymus medulla J:264357
increased osteoclast cell number J:264357
Tg(APOA1)1Rub/Tg(APOA1)1Rub
(C57BL/6-Tg(APOA1)1Rub/J)
abnormal circulating interleukin-17 level J:190966
abnormal spleen weight J:190966
Tg(APOC1)1Lmh/Tg(APOC1)1Lmh
(C57BL/6-Tg(APOC1)1Lmh)
dermatitis J:65036
enlarged spleen J:65036
folliculitis J:65036
Tg(APOC1)1Lmh/Tg(APOC1)1Lmh
(involves: C57BL/6)
dermatitis J:135501
increased IgE level J:135501
increased mast cell degranulation J:135501
skin inflammation J:135501
Tg(APOE-DGAT1)1Far/0
(involves: C57BL/6NHsd)
liver inflammation J:124005
Tg(APOE-DGAT2)1Far/0
(involves: C57BL/6NHsd)
liver inflammation J:124005
Tg(APOE-FGF23*R176Q)#Ack/0
(involves: C57BL/6J * CBA)
decreased osteoclast cell number J:93981
enthesitis J:192371
Tg(APP695)3Dbo/0
Tg(PSEN1dE9)S9Dbo/0

(Not Specified)
abnormal microglial cell morphology J:139070
Tg(APPSWE)2576Kha/0
(involves: C57BL/6 * SJL)
microgliosis J:159623
Tg(APPswe,PSEN1dE9)85Dbo/0
(D2.Cg-Tg(APPswe,PSEN1dE9)85Dbo)
microgliosis J:227541
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0
(involves: C57BL/6 * SJL)
brain inflammation J:112949
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
(involves: C57BL/6 * SJL)
increased microglial cell activation J:208030
Tg(ARR2/Pbsn-FGF8)3Prb/0
(involves: C57BL/6 * DBA/2)
increased inflammatory response J:78918
prostate gland inflammation J:78918
Tg(B2M)55Hpl/?
Tg(CD8aCD8b)57Scr/?
Tg(HLA-B)22Hpl/?

(involves: C57BL/6 * C57BL/LiA * CBA)
abnormal cytotoxic T cell physiology J:127813
Tg(B2M,HLA-B*27:05)56-3Trg/0
(involves: C57BL/6 * SJL/J)
immune system phenotype J:74451
Tg(B19-RNAi:Il3)241Ckn/?
(involves: BALB/cJ * C57BL/6J * FVB/N)
abnormal B cell differentiation J:107618
decreased interleukin-3 secretion J:107618
enlarged lymph nodes J:107618
enlarged spleen J:107618
increased pre-B cell number J:107618
Tg(BCL2)22Wehi/0
(involves: C57BL/6JWehi * SJL/JWehi)
abnormal B cell differentiation J:93111
abnormal B cell physiology J:93111
increased B cell number J:93111
increased susceptibility to autoimmune disorder J:93111
Tg(BCL2)22Wehi/0
(involves: C57BL/6J * C57BL/6JWehi)
increased B cell number J:88565
Tg(BCL2)22Wehi/0
Tg(IghMyc)22Bri/0

(involves: C57BL/6 * C57BL/6JWehi * SJL/J * SJL/JWehi)
abnormal B cell morphology J:69571
abnormal pre-B cell morphology J:69571
enlarged lymph nodes J:69571
enlarged spleen J:69571
enlarged thymus J:69571
increased B cell number J:69571
increased leukocyte cell number J:69571
increased pre-B cell number J:69571
Tg(BCL2)25Wehi/0
(involves: C57BL/6JWehi * SJL/JWehi)
abnormal B cell differentiation J:131912
abnormal plasma cell differentiation J:131912
abnormal T cell physiology J:93111
increased T cell number J:93111
Tg(BCL2)36Wehi/0
(involves: C57BL/6JWehi * SJL/JWehi)
abnormal B cell physiology J:93111
abnormal T cell physiology J:93111
increased B cell number J:93111
increased immunoglobulin level J:93111
increased susceptibility to autoimmune disorder J:93111
increased T cell number J:93111
Tg(BCL2)36Wehi/?
(B6.Cg-Tg(BCL2)36Wehi/J)
abnormal B cell proliferation J:90963
decreased B cell apoptosis J:90963
Tg(BCL2/IGH)1Tjd/?
(involves: C3H/He * C57BL/6)
abnormal B cell physiology J:81147
abnormal lymph node morphology J:81147
abnormal mononuclear cell differentiation J:81147
enlarged lymph nodes J:81147
enlarged spleen J:81147
increased B cell number J:81147
increased spleen white pulp amount J:81147
spleen hyperplasia J:81147
Tg(BCL2/IGH)#Jcre/0
Tg(H2-K/Igh-Traf2*)#Ywc/0

(involves: BALB/c * C57BL/6 * CBA/J * FVB/N * SJL/J * SWR/J)
abnormal spleen marginal zone morphology J:94116
decreased B cell apoptosis J:94116
enlarged lymph nodes J:94116
enlarged spleen J:94116
increased B cell number J:94116
increased B-1a cell number J:94116
increased B-1b cell number J:94116
increased marginal zone B cell number J:94116
increased spleen weight J:94116
Tg(BCL2/IGH)M23Tjd/?
(involves: C3H/He * C57BL/6)
abnormal B cell physiology J:81147
abnormal lymph node morphology J:81147
abnormal mononuclear cell differentiation J:81147
enlarged lymph nodes J:81147
enlarged spleen J:81147
increased B cell number J:81147
increased spleen white pulp amount J:81147
spleen hyperplasia J:81147
Tg(BLG-STAT5A)15Itb/0
(involves: FVB/N)
increased inflammatory response J:80588
Tg(C9orf72)500Lpwr/0
(FVB/NJ-Tg(C9orf72)500Lpwr)
microgliosis J:239579
Tg(CAG-ACE2)AC63Ctkt/0
(either: (involves: BALB/c * C3H/HeJ * C57BL/6J) or (involves: C3H/HeJ * C57BL/6 * C57BL/6J))
increased susceptibility to Coronaviridae infection J:117824
Tg(CAG-ACE2)AC70Ctkt/0
(either: (involves: BALB/c * C3H/HeJ * C57BL/6J) or (involves: C3H/HeJ * C57BL/6 * C57BL/6J))
abnormal cytokine level J:117824
increased susceptibility to Coronaviridae infection J:117824
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:117824
interstitial pneumonia J:117824
Tg(CAG-APP)0304Shoj/0
(involves: C3H * C57BL/6N)
abnormal circulating serum amyloid protein level J:100977
Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi/0
Tg(Flt4-cre)44Ichi/0

(involves: 129P2/OlaHsd * C57BL/6J)
lymphatic vessel hyperplasia J:159024
Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi/0
Tg(Tek-cre)12Flv/0

(involves: 129P2/OlaHsd * C3H * C57BL/6)
lymphatic vessel hyperplasia J:159024
Tg(CAG-Btc)2Ewo/0
(FVB/N-Tg(CAG-Btc)2Ewo)
increased spleen weight J:103364
Tg(CAG-Btc)4Ewo/0
(FVB/N-Tg(CAG-Btc)4Ewo)
increased spleen weight J:103364
Tg(CAG-C1qtnf6)#Yiw/0
(involves: C57BL/6JJcl)
abnormal complement protein level J:227217
decreased IgG level J:227217
decreased susceptibility to induced arthritis J:227217
impaired complement alternative pathway J:227217
Tg(CAG-cat,-Il18)#Thos/0
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0

(involves: 129 * C57BL/6)
increased interferon-gamma secretion J:147547
interstitial pneumonia J:147547
Tg(CAG-cre/Esr1*)5Amc/0
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
microgliosis J:221181
Tg(CAG-DPP4)4Yuzh/0
(C57BL/6-Tg(CAG-DPP4)4Yuzh)
abnormal circulating cytokine level J:286175
abnormal spleen morphology J:286175
brain inflammation J:286175
increased circulating interferon-gamma level J:286175
increased circulating interleukin-17 level J:286175
increased susceptibility to Coronaviridae infection J:286175
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:286175
kidney inflammation J:286175
liver inflammation J:286175
lung inflammation J:286175
Tg(CAG-DPP4)52Ctkt/0
(involves: C3H/HeJ * C57BL/6J)
abnormal mononuclear cell morphology J:227925
brain inflammation J:227925
increased inflammatory response J:227925
increased microglial cell activation J:227925
increased susceptibility to Coronaviridae infection J:227925, J:258199
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:227925, J:258199
interstitial pneumonia J:258199
lung inflammation J:227925
Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu/0
(involves: C57BL/6 * C57BL/6J * FVB/NJ * SJL)
microgliosis J:207750
Tg(CAG-Has2)99Nita/0
Tg(MMTV-cre)4Mam/0
Tg(MMTVneu)202Mul/0

(FVB.Cg-Tg(CAG-Has2)99Nita Tg(MMTV-cre)4Mam Tg(MMTVneu)202Mul)
abnormal lymphatic vessel morphology J:130531
impaired macrophage chemotaxis J:164205
increased macrophage cell number J:164205
Tg(CAG-Has2)99Nita/0
Tg(MMTVneu)202Mul/0

(FVB.Cg-Tg(CAG-Has2)99Nita Tg(MMTVneu)202Mul)
abnormal lymphatic vessel morphology J:130531
Tg(CAG-LacZ,-ACVR1*,-EGFP)35-1Mis/0
(involves: C57BL/6 * DBA/2)
myositis J:142253
Tg(CAG-Lyn*)#Paau/0
(B6.Cg-Tg(CAG-Lyn*)#Paau)
skin inflammation J:151886
Tg(CAG-Ncoa6)71Hwl/0
(involves: FVB)
lung inflammation J:80609
spleen atrophy J:80609
thymus atrophy J:80609
Tg(CAG-Ncoa6)87Hwl/0
(involves: FVB)
lung inflammation J:80609
spleen atrophy J:80609
thymus atrophy J:80609
Tg(CAG-Ncoa6)104Hwl/0
(involves: FVB)
spleen atrophy J:80609
thymus atrophy J:80609
Tg(CAG-NRIP1)51Row/0
(involves: FVB/N)
lung inflammation J:175885
Tg(CAG-OVAL)916Jen/?
(C57BL/6-Tg(CAG-OVAL)916Jen)
abnormal dendritic cell antigen presentation J:91742
decreased length of allograft survival J:91742
Tg(CAG-p35)1Miur/0
(involves: C57BL/6)
autoimmune response J:126593
Tg(CAG-p35)1Miur/0
Tg(Mbp-cre)29Miur/0

(involves: C57BL/6)
decreased susceptibility to experimental autoimmune encephalomyelitis J:126593
Tg(CAG-Pgam2)#Hiko/0
(involves: C57BL/6)
increased susceptibility to chemically induced skin inflammation J:306793
Tg(CAG-PGDS)1Groy/0
(involves: FVB/N)
abnormal cytokine secretion J:107651
abnormal lymph node morphology J:107651
decreased inflammatory response J:107651
Tg(CAG-PLA2G3)#aMurm/0
(Not Specified)
increased mast cell degranulation J:197334
increased susceptibility to type I hypersensitivity reaction J:197334
Tg(CAG-Ptafr)1Tksh/0
(B6;D2-Tg(CAG-Ptafr)1Tksh/TkshRbrc)
increased mast cell number J:38639
increased susceptibility to endotoxin shock J:38639
Tg(CAG-SPTLC1*C133W)8EAmcc/0
(involves: C3H * C57BL/6)
microgliosis J:155748
Tg(CAG-SYVN1)1Tn/?
(D1.Cg-Tg(CAG-SYVN1)1Tn)
rheumatoid arthritis J:86009
Tg(Camk2a-cre)2Gsc/0
Tg(H2-Ld)LoxNibl/0

(involves: C57BL/6 * FVB/N)
immune system phenotype J:284394
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-APPSwInd)107Dbo/0

(involves: C3H/HeJ * C57BL/6 * CBA)
CNS inflammation J:109829
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-APPSwInd)Dbo/0

(involves: C3H/HeJ * C57BL/6J)
microgliosis J:236737
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-LRRK2)C77Cai/0
Tg(tetO-SNCA*A53T)E2Cai/0

(involves: C57BL/6)
microgliosis J:156512
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-LRRK2)C7874Cai/0
Tg(tetO-SNCA*A53T)E2Cai/0

(involves: C57BL/6)
microgliosis J:156512
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-LRRK2*G2019S)E3Cai/0
Tg(tetO-SNCA*A53T)E2Cai/0

(involves: C57BL/6)
microgliosis J:156512
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-Mtor*)#Atai/0

(involves: C57BL/6 * DBA/2 * ICR)
microgliosis J:211789
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-SNCA*A53T)E2Cai/0

(involves: C57BL/6)
microgliosis J:156512
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-TARDBP)12Vle/0

(involves: C3H/HeJ * C57BL/6J)
microgliosis J:170756
Tg(CD2-Ccdc86)1Hfuj/?
(B6.FVB-Tg(CD2-Ccdc86)1Hfuj)
abnormal T cell morphology J:151722
increased T cell apoptosis J:151722
Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
(NOD/MrkTac-Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell)
immune system phenotype J:86540
Tg(CD2-Ceacam1*4L)1Rsb/0
(involves: C57BL/6)
abnormal T cell physiology J:116136
decreased interleukin-2 secretion J:116136
decreased T cell number J:116136
decreased T cell proliferation J:116136
Tg(CD2-Ceacam1*4L)1Rsb/0
Tg(TcraTcrb)425Cbn/0

(involves: BALB/c * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:116136
Tg(CD2-Foxj1)#Stlp/0
(C57BL/6-Tg(CD2-Foxj1)#Stlp)
abnormal T cell physiology J:122222
decreased CD4-positive, alpha-beta T cell number J:122222
decreased CD8-positive, alpha-beta T cell number J:122222
immune system phenotype J:122222
increased single-positive T cell number J:122222
lymphoid hypoplasia J:122222
Tg(CD2-Ifngr2)1Pbro/?
(B6.Cg-Tg(CD2-Ifngr2)1Pbro)
abnormal T-helper 1 cell differentiation J:134448
abnormal T-helper 1 physiology J:134448
decreased susceptibility to type IV hypersensitivity reaction J:134448
immune system phenotype J:134448
increased susceptibility to parasitic infection J:134448
Tg(CD2-Ifngr2)2Pbro/?
(B6.Cg-Tg(CD2-Ifngr2)2Pbro)
abnormal T-helper 1 cell differentiation J:134448
abnormal T-helper 1 physiology J:134448
immune system phenotype J:134448
increased susceptibility to parasitic infection J:134448
Tg(CD2-Ifngr2)2Pbro/?
(NOD.Cg-Tg(CD2-Ifngr2)2Pbro)
abnormal splenic cell ratio J:81981
abnormal T-helper 1 physiology J:81981
decreased interferon-gamma secretion J:81981
decreased interleukin-4 secretion J:81981
decreased tumor necrosis factor secretion J:81981
immune system phenotype J:81981
insulitis J:81981
myositis J:81981
ovary inflammation J:81981
Tg(CD2-LAT2)1Wz/0
(Not Specified)
abnormal CD8-positive, alpha-beta T cell physiology J:116157
Tg(CD2-Lmo2)#Thr/0
(involves: C57BL/6 * CBA)
enlarged spleen J:102058
enlarged thymus J:102058
Tg(CD2-Lrch1)#Liux/0
(involves: C57BL/6)
abnormal cellular extravasation J:238772
decreased susceptibility to experimental autoimmune encephalomyelitis J:238772
immune system phenotype J:238772
Tg(CD2-Mir181d)38Oers/0
(involves: C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:212571
decreased double-positive T cell number J:212571
decreased T cell number J:212571
immune system phenotype J:212571
thymus atrophy J:212571
Tg(CD2-Mir181d)38Oers/0
Tg(TcraTcrb)425Cbn/0

(involves: C3H * C57BL/6)
decreased T cell number J:212571
Tg(CD2-Myb/en)2Kmw/?
(involves: C57BL/10 * CBA)
abnormal single-positive T cell number J:126456
decreased T cell number J:126456
decreased T cell proliferation J:126456
increased double-negative T cell number J:126456
Tg(CD2-Myb/en)2Kmw/Tg(CD2-Myb/en)2Kmw
(involves: C57BL/10 * CBA)
decreased double-positive T cell number J:126456
decreased T cell number J:126456
decreased T cell proliferation J:126456
increased double-negative T cell number J:126456
small spleen J:126456
small thymus J:126456
Tg(CD2-Nfat5)1Snh/0
(involves: BALB/c * C57BL/6)
abnormal cytotoxic T cell physiology J:80066
abnormal T cell differentiation J:80066
abnormal T cell physiology J:80066
decreased CD4-positive, alpha-beta T cell number J:80066
decreased CD8-positive, alpha-beta T cell number J:80066
decreased splenocyte proliferation J:80066
decreased T cell number J:80066
decreased T cell proliferation J:80066
spleen hypoplasia J:80066
thymus hypoplasia J:80066
Tg(CD2-Ppp2ca)#Gct/0
(involves: C57BL/6J)
abnormal T cell subpopulation ratio J:184067
enlarged lymph nodes J:184067
enlarged spleen J:184067
glomerulonephritis J:184067
increased germinal center B cell number J:184067
increased interleukin-17 secretion J:184067
increased neutrophil cell number J:184067
Tg(CD2-Rorc)#Staka/0
(involves: C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:236222
abnormal susceptibility to Picornaviridae infection J:236222
abnormal T-helper 17 cell physiology J:236222
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:230700
decreased CD8-positive, alpha-beta T cell number J:236222
decreased IgG2c level J:236222
decreased IgG3 level J:236222
decreased IgG level J:236222
decreased interferon-gamma secretion J:236222
decreased interleukin-10 secretion J:236222
increased anti-nuclear antigen antibody level J:230700
increased autoantibody level J:230700
increased effector memory CD4-positive, alpha-beta T cell number J:230700
increased interferon-gamma secretion J:236222
increased interleukin-17 secretion J:236222
increased susceptibility to autoimmune disorder J:230700
lacrimal gland inflammation J:230700
lung inflammation J:230700
salivary gland inflammation J:230700
Tg(CD2-S1PR1)1Ejg/?
(involves: C57BL/6 * DBA/2)
abnormal humoral immune response J:96558
abnormal lymphocyte chemotaxis J:96558
decreased activated T cell number J:96558
decreased susceptibility to type IV hypersensitivity reaction J:96558
decreased T cell proliferation J:96558
impaired leukocyte migration J:96558
increased activated T cell number J:96558
increased IgE level J:96558
increased T cell number J:96558
Tg(CD2-Sh2d1a)#Vei/0
(involves: 129S1/Sv * 129X1/SvJ)
increased natural killer cell mediated cytotoxicity J:110195
Tg(CD2-Sh2d1b1)#Vei/0
(B6.Cg-Tg(CD2-Sh2d1b1)#Vei)
decreased interferon-gamma secretion J:110195
impaired natural killer cell mediated cytotoxicity J:110195
Tg(CD2-Sh2d1b2)#Vei/0
(B6.Cg-Tg(CD2-Sh2d1b2)#Vei)
impaired natural killer cell mediated cytotoxicity J:110195
Tg(Cd2-Smad7)#Chbe/0
(involves: C57BL/6)
abnormal T-helper 1 cell differentiation J:184670
decreased interleukin-9 secretion J:184670
decreased interleukin-10 secretion J:184670
decreased interleukin-17 secretion J:184670
increased interferon-gamma secretion J:184670
increased susceptibility to experimental autoimmune encephalomyelitis J:184670
Tg(CD2-Stat6*V625A*T626A)78Mhk/0
(involves: C3H * C57BL/6)
dermatitis J:160119
Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/0
(involves: C57BL/10)
abnormal positive T cell selection J:113713
increased CD8-positive, alpha-beta T cell number J:113713
Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/0
(involves: C57BL/10 * CBA/Ca)
decreased CD8-positive, alpha-beta T cell number J:113713
Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/0
(involves: BALB/c * C57BL/10)
decreased CD8-positive, alpha-beta T cell number J:113713
Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/?
(involves: 129S1/Sv * 129X1/SvJ * C57BL/10 * FVB/N)
abnormal positive T cell selection J:126026
decreased CD4-positive, alpha-beta T cell number J:126026
increased CD8-positive, alpha-beta T cell number J:126026
Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/0
Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0

(involves: C57BL/6 * C57BL/10)
abnormal T cell clonal deletion J:217939
decreased thymocyte apoptosis J:217939
enlarged lymph nodes J:217939
increased T cell number J:217939
Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/0
Tg(LCKprBCL2)36Sjk/0

(involves: C57BL/6 * C57BL/10)
abnormal T cell clonal deletion J:217939
decreased thymocyte apoptosis J:217939
Tg(CD2-Tgfbr2)1Grs/0
(C57BL/6-Tg(CD2-Tgfbr2)1Grs/Nci)
enlarged lymph nodes J:97523
enlarged spleen J:97523
increased T cell proliferation J:97523
Tg(CD2-Tgfbr2)1Grs/?
(C57BL/6-Tg(CD2-Tgfbr2)1Grs/Nci)
abnormal CD8-positive, alpha beta T cell morphology J:93665
increased T cell proliferation J:93665
Tg(CD2-Zbtb7b)C8Rbo/?
(involves: C57BL/6)
absent CD8-positive, alpha-beta T cells J:97610
increased CD4-positive, alpha-beta T cell number J:97610
Tg(CD2-Zbtb7b)C8Rbo/?
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: C57BL/6 * DBA/2J)
abnormal T cell differentiation J:97610
Tg(CD2-Zbtb7b)C8Rbo/?
Tg(TcrLCMV)327Sdz/?

(involves: C57BL/6 * DBA/2J)
abnormal T cell differentiation J:97610
Tg(CD2-Zbtb7b)C8Rbo/?
Themistm1Lov/Themistm1Lov

(involves: 129)
abnormal T cell differentiation J:151075
Tg(Cd3d-Il5)NJ.1638Nal/?
(involves: C57BL/6J * CBA/J)
abnormal eosinophil differentiation J:123440
abnormal spleen morphology J:123440
abnormal T cell number J:123440
enlarged lymph nodes J:123440
increased eosinophil cell number J:123440
increased leukocyte cell number J:123440
increased mature B cell number J:123440
increased monocyte cell number J:123440
increased neutrophil cell number J:123440
increased spleen weight J:123440
peritoneal inflammation J:123440
Tg(CD3E)26Cpt/Tg(CD3E)26Cpt
(involves: C57BL/6J * CBA/J)
abnormal thymus corticomedullary boundary morphology J:81711
absent NK cells J:81711
arrested T cell differentiation J:81711
decreased double-positive T cell number J:54756
decreased T cell number J:54756
decreased thymocyte number J:81711
decreased uterine NK cell number J:134589
thymus hypoplasia J:54756
Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell number J:217939
abnormal mesenteric lymph node morphology J:217939
abnormal splenic cell ratio J:217939
abnormal T cell clonal deletion J:217939
abnormal T cell proliferation J:217939
abnormal T cell subpopulation ratio J:217939
decreased double-positive T cell number J:217939
decreased thymocyte apoptosis J:217939
enlarged lymph nodes J:217939
enlarged spleen J:217939
glomerulonephritis J:217939
increased activated T cell number J:217939
increased anti-nuclear antigen antibody level J:217939
increased autoantibody level J:217939
increased B cell number J:217939
increased central memory CD8 positive, alpha-beta T cell number J:217939
increased interferon-gamma secretion J:217939
increased regulatory T cell number J:217939
increased single-positive T cell number J:217939
increased susceptibility to autoimmune disorder J:217939
increased T cell number J:217939
kidney inflammation J:217939
liver inflammation J:217939
lung inflammation J:217939
lymphoid hyperplasia J:217939
skin inflammation J:217939
Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0
(involves: C57BL/6 * CBA/J)
abnormal T cell clonal deletion J:217939
decreased thymocyte apoptosis J:217939
Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0
Tg(Nr4a1-EGFP/cre)820Khog/0

(involves: C57BL/6 * C57BL/6J)
abnormal T cell clonal deletion J:217939
decreased thymocyte apoptosis J:217939
Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C57BL/6 * C57BL/6J * DBA/2J)
abnormal T cell clonal deletion J:217939
decreased thymocyte apoptosis J:217939
Tg(Cd4-CD4)2362Litt/0
(involves: C57BL/6 * SJL)
immune system phenotype J:50435
Tg(Cd4-CD4)2362Litt/0
Tg(HLA-DR2)#Lfug/0
Tg(TCROb.1A12)#Lfug/0

(involves: C57BL/6 * DBA/2 * SJL)
CNS inflammation J:134764
increased susceptibility to experimental autoimmune encephalomyelitis J:134764
Tg(CD4-CIITA)357Ccum/?
(involves: C57BL/6 * C57BL/6J * SJL)
increased osteoclast cell number J:233241
Tg(Cd4-cre)1Cwi/?
Tg(TcraTcrb)425Cbn/?
Traf6tm2Ywc/Traf6tm2Ywc

(involves: C57BL/6 * DBA/2)
abnormal lymphocyte anergy J:130882
increased interleukin-2 secretion J:130882
Tg(Cd4-cre)1Cwi/0
Trmt6em1Hbgl/Trmt6em1Hbgl

(involves: C57BL/6 * DBA/2J)
decreased CD4-positive, alpha-beta T cell number J:336736
decreased T cell proliferation J:336736
Tg(Cd4-cre)1Cwi/0
Trmt61aem1Hbgl/Trmt61aem1Hbgl

(involves: C57BL/6 * DBA/2J)
abnormal CD4-positive T cell differentiation J:336736
abnormal T cell activation J:336736
colitis J:336736
decreased CD4-positive, alpha-beta T cell number J:336736
decreased CD8-positive, alpha-beta T cell number J:336736
decreased T cell proliferation J:336736
increased CD4-positive, alpha-beta T cell number J:336736
increased CD8-positive, alpha-beta T cell number J:336736
Tg(Cd4-DsRed)4Lt/0
(NOD/ShiLt-Tg(Cd4-DsRed)4Lt)
decreased susceptibility to autoimmune diabetes J:127785
Tg(Cd4-Dtx1)1Mzl/?
(involves: C57BL/6)
abnormal T cell activation J:151605
abnormal thymocyte activation J:151605
decreased interleukin-2 secretion J:151605
decreased T cell proliferation J:151605
Tg(CD4-HIV)F21380Pjo/0
(involves: C3H * C57BL/6)
interstitial pneumonia J:78756
lymph node atrophy J:78756
spleen atrophy J:78756
thymus atrophy J:78756
tubular nephritis J:78756
Tg(CD4-HIV)F21388Pjo/0
(involves: C3H * C57BL/6)
interstitial pneumonia J:78756
lymph node atrophy J:78756
spleen atrophy J:78756
thymus atrophy J:78756
tubular nephritis J:78756
Tg(CD4-HIV)F21407Pjo/0
(involves: C3H * C57BL/6)
interstitial pneumonia J:78756
lymph node atrophy J:78756
spleen atrophy J:78756
thymus atrophy J:78756
tubular nephritis J:78756
Tg(CD4-HIV)F26605Pjo/0
(involves: C3H * C57BL/6)
interstitial pneumonia J:78756
lymph node atrophy J:78756
spleen atrophy J:78756
thymus atrophy J:78756
tubular nephritis J:78756
Tg(CD4-HIV)F26622Pjo/0
(involves: C3H * C57BL/6)
interstitial pneumonia J:78756
lymph node atrophy J:78756
spleen atrophy J:78756
thymus atrophy J:78756
tubular nephritis J:78756
Tg(CD4-HIV)F26990Pjo/0
(involves: C3H * C57BL/6)
interstitial pneumonia J:78756
lymph node atrophy J:78756
spleen atrophy J:78756
thymus atrophy J:78756
tubular nephritis J:78756
Tg(CD4-HIV)F27011Pjo/0
(involves: C3H * C57BL/6)
interstitial pneumonia J:78756
lymph node atrophy J:78756
spleen atrophy J:78756
thymus atrophy J:78756
tubular nephritis J:78756
Tg(CD4-HIV)F27367Pjo/0
(involves: C3H * C57BL/6)
interstitial pneumonia J:78756
lymph node atrophy J:78756
spleen atrophy J:78756
thymus atrophy J:78756
tubular nephritis J:78756
Tg(Cd4-Il17rb)#Cdon/?
(involves: C57BL/6)
abnormal T cell differentiation J:158594
decreased interferon-gamma secretion J:158594
increased eosinophil cell number J:158594
increased interleukin-5 secretion J:158594
increased interleukin-9 secretion J:158594
increased interleukin-13 secretion J:158594
increased susceptibility to type I hypersensitivity reaction J:158594
lung inflammation J:158594
Tg(CD4-Il17re)#Cdon/0
(involves: C57BL/6)
abnormal interleukin secretion J:177650
decreased interleukin-17 secretion J:177650
increased susceptibility to experimental autoimmune encephalomyelitis J:177650
Tg(Cd4-NPM/ALK)N1Ingh/0
(either: (involves: BALB/c * Swiss Webster) or (involves: C57BL/6 * Swiss Webster))
increased immunoglobulin level J:82127
Tg(Cd4-NPM/ALK)N1Ingh/0
(involves: C57BL/6 * Swiss Webster)
abnormal T cell differentiation J:235890
abnormal T cell morphology J:235890
increased DN3 thymocyte number J:235890
Tg(Cd4-NPM/ALK)N1Ingh/0
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6 * Swiss Webster)
abnormal double-negative T cell morphology J:235890
abnormal thymus morphology J:235890
Tg(Cd4-TGFBR2)16Flv/?
(involves: C3H * C57BL/6 * C57BL/10 * C57BR/cd)
abnormal T cell activation J:97554
abnormal T cell proliferation J:97554
abnormal thymus involution J:97554
colitis J:97554
decreased B cell number J:97554
glomerulonephritis J:97554
increased anti-nuclear antigen antibody level J:97554
increased IgA level J:97554
increased IgG1 level J:97554
increased IgG2a level J:97554
increased immunoglobulin level J:97554
increased inflammatory response J:97554
increased memory T cell number J:97554
liver inflammation J:97554
lung inflammation J:97554
lymph node hyperplasia J:97554
pancreas inflammation J:97554
spleen hyperplasia J:97554
Tg(Cd4-TGFBR2)16Flv/?
(involves: C3H * C57BL/6)
abnormal CD8-positive, alpha-beta regulatory T cell morphology J:134473
abnormal T cell proliferation J:134473
colitis J:134156
increased interferon-gamma secretion J:134156
increased tumor necrosis factor secretion J:134156
Tg(Cd4-Zbtb16)1797Aben/?
(C57BL/6-Tg(Cd4-Zbtb16)1797Aben)
decreased CD4-positive, alpha-beta T cell number J:139690
increased CD4-positive, alpha-beta memory T cell number J:139690
increased T-helper 2 cell number J:139690
Tg(Cd8aCd8b)3Erob/0
(involves: C57BL/6 * DBA/2)
abnormal CD8-positive, alpha-beta T cell differentiation J:93004
abnormal double-positive T cell morphology J:93004
decreased CD4-positive, alpha-beta T cell number J:93004
decreased double-negative T cell number J:93004
increased CD8-positive, alpha-beta T cell number J:93004
Tg(Cd8aCd8b)3Erob/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C57BL/6 * DBA/2)
abnormal CD4-positive, alpha beta T cell morphology J:93004
abnormal CD8-positive, alpha-beta T cell differentiation J:93004
increased CD8-positive, alpha-beta T cell number J:93004
Tg(CD8aCD8b)57Scr/?
(B6;SJL-Tg(CD8aCD8b)57Scr/J)
abnormal cytotoxic T cell physiology J:92994
abnormal effector T cell morphology J:92994
Tg(Cd8b1)46Erob/0
(involves: 129S4/SvJae * C57BL/6 * CBA)
abnormal T cell subpopulation ratio J:110916
decreased T cell number J:110916
decreased thymocyte number J:110916
Tg(CD19)1Tft/0
(involves: C57BL/6 * C57BL/6J * SJL)
decreased B cell number J:27236
increased B cell proliferation J:27236
Tg(CD19)1Tft/Tg(CD19)1Tft
(involves: C57BL/6 * C57BL/6J * SJL)
decreased B cell number J:27236
decreased IgG1 level J:27236
decreased IgG3 level J:27236
decreased immature B cell number J:27236
increased B cell proliferation J:27236
increased IgG2a level J:27236
increased IgG2b level J:27236
increased IgM level J:27236
Tg(CD19-Tnfsf7)#Rvl/0
(involves: C57BL/6)
abnormal metallophilic macrophage morphology J:88620
abnormal spleen marginal zone macrophage morphology J:88620
abnormal spleen marginal zone morphology J:88620
decreased B cell number J:88620
decreased mature B cell number J:88620
decreased transitional stage B cell number J:88620
Tg(CD46)2Gsv/0
(involves: C57BL/6 * FVB/N)
abnormal cell-mediated immunity J:109895
abnormal chemokine level J:109895
abnormal cytokine secretion J:109895
abnormal humoral immune response J:109895
abnormal response to transplant J:113644
decreased cytotoxic T cell cytolysis J:109895
increased susceptibility to Paramyxoviridae infection J:109895
Tg(CD46)373Zbz/Tg(CD46)373Zbz
(involves: C3H/He * C57BL/6)
immune system phenotype J:160878
Tg(Cd68-BCL2)526Medz/0
(involves: 129 * C57BL/6)
abnormal immune cell physiology J:82809
increased inflammatory response J:82809
Tg(Cd68-BCL2)533Medz/0
(involves: 129 * C57BL/6)
abnormal immune system cell morphology J:82809
Tg(Cd68-BCL2)535Medz/0
(involves: 129 * C57BL/6)
abnormal dendritic cell physiology J:211458
decreased dendritic cell apoptosis J:211458
enlarged lymph nodes J:82809
enlarged spleen J:82809
increased inflammatory response J:82809
Tg(Cd68-Fem1a)1Seno/0
(C57BL/6-Tg(Cd68-Fem1a)1Seno)
abnormal susceptibility to induced colitis J:228893
Tg(Cd74-Nlrc4*)1Kyas/0
(involves: C57BL/6N)
abnormal spleen morphology J:219652
arthritis J:219652
dermatitis J:219652
enlarged spleen J:219652
increased circulating interleukin-1 beta level J:219652
increased circulating interleukin-17 level J:219652
increased inflammatory response J:219652
increased interleukin-1 beta secretion J:219652
increased neutrophil cell number J:219652
increased splenocyte number J:219652
increased T cell number J:219652
joint inflammation J:219652
skin inflammation J:219652
Tg(Cd79b-TCL1A)BKTeit/0
(involves: C3H * C57BL/6)
abnormal lymph node morphology J:79703
abnormal spleen morphology J:79703
abnormal thymus morphology J:79703
decreased B cell apoptosis J:79703
decreased T cell apoptosis J:79703
enlarged lymph nodes J:79703
enlarged spleen J:79703
increased B cell proliferation J:79703
increased lymphocyte cell number J:79703
increased T cell proliferation J:79703
Tg(Cd152Ig)1Jbs/0
(involves: C3H * NOD)
increased susceptibility to autoimmune diabetes J:35353
Tg(CD207-Dta)312Dhka/?
(FVB-Tg(CD207-Dta)312Dhka)
absent Langerhans cell J:113309
increased susceptibility to type IV hypersensitivity reaction J:113309
Tg(Cebpb-tTA)5Bjd/0
Tg(tetO-MYC,-OVAL)#Gtgm/0

(B6J.Cg-Tg(Cebpb-tTA)5Bjd Tg(tetO-MYC,-OVAL)#Gtgm)
abnormal immune tolerance J:186226
Tg(Cga-LHB/CGB)94Jhn/?
(involves: C57BL/6 * SJL)
pyelonephritis J:55157
tubulointerstitial nephritis J:55157
Tg(Chst4-cre)1Hkwa/0
(involves: C3H/HeN * C57BL/6)
immune system phenotype J:147714
Tg(Ckm-APPSw)A2Lfa/0
(involves: C57BL/6 * SJL)
myositis J:76338
Tg(Ckm-APPSw)A6Lfa/0
(involves: C57BL/6 * SJL)
myositis J:76338
Tg(CKMM-tTA)A3Rhvh/0
Tg(tetO-H2-K1)#Papl/0

(B6.Cg-Tg(CKMM-tTA)A3Rhvh Tg(tetO-H2-K1)#Papl)
abnormal cytokine level J:205907
increased anti-nuclear antigen antibody level J:205907
increased autoantibody level J:205907
myositis J:205907
Tg(CLEC4C-HBEGF)956Cln/0
(C57BL/6-Tg(CLEC4C-HBEGF)956Cln)
abnormal chemokine secretion J:166504
abnormal cytotoxic T cell physiology J:166504
abnormal NK cell physiology J:166504
abnormal NK T cell physiology J:166504
decreased CD8-positive, alpha-beta T cell number J:166504
decreased interferon-alpha secretion J:166504
decreased plasmacytoid dendritic cell number J:166504
decreased splenocyte number J:166504
impaired natural killer cell mediated cytotoxicity J:166504
increased interferon-gamma secretion J:166504
increased interleukin-12 secretion J:166504
increased susceptibility to Herpesvirales infection J:166504
small spleen J:166504
Tg(Cma1-cre)ARoer/0
Tg(Kit*D814V)1Roer/0

(involves: C57BL/6)
colitis J:169611
increased mast cell number J:169611
Tg(Cma1-cre)ARoer/0
Tg(Kit*D814V)3Roer/0

(involves: C57BL/6)
increased mast cell number J:169611
Tg(CMV-cre)1Cgn/0
Tg(Kit*D814V)1Roer/0

(involves: BALB/cJ * C57BL/6)
increased mast cell number J:169611
large intestinal inflammation J:169611
Tg(CMV-cre)1Cgn/0
Tg(Kit*D814V)3Roer/0

(involves: BALB/cJ * C57BL/6)
increased mast cell number J:169611
Tg(CMV-cre)1Cgn/0
Trp53tm4Att/Trp53+

(involves: 129S4/SvJae * BALB/cJ * C57BL/6J)
small thymus J:217080
Tg(CMV-IghvaD11)CCat/0
Tg(CMV-IgkvaD11)BCat/0

(involves: C57BL/6 * SJL)
abnormal splenic cell ratio J:79946
increased splenocyte apoptosis J:79946
Tg(CMV-IghvaD11)DCat/0
Tg(CMV-IgkvaD11)ACat/0

(involves: C57BL/6 * SJL)
abnormal splenic cell ratio J:79946
increased splenocyte apoptosis J:79946
Tg(CMV-SALL4_iB)#Chai/?
(Not Specified)
abnormal leukocyte morphology J:115037
abnormal myelopoiesis J:115037
abnormal neutrophil morphology J:115037
decreased leukocyte cell number J:115037
decreased neutrophil cell number J:115037
myeloid hyperplasia J:115037
Tg(CMV-tTA)3Bjd/0
Tg(tetO-Prkar1a*x2as)1Stra/0

(involves: C57BL/6 * NMRI * SJL)
abnormal lymph node morphology J:94953
pancreas inflammation J:94953
Tg(Cnp-EGFR)10Nrat/0
(involves: C57BL/6 * SJL)
increased mast cell number J:95933
Tg(Cnp-Gpr17)1Qrlu/0
(Not Specified)
microgliosis J:154602
Tg(Col1a1-cre)1Kry/0
Vdrtm2Ska/Vdrtm2Ska

(involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * FVB/N)
abnormal osteoclast differentiation J:196471
decreased osteoclast cell number J:196471
Tg(Col1a1-Dkk1)1Hmk/?
(B6.FVB-Tg(Col1a1-Dkk1)1Hmk)
abnormal osteoclast physiology J:158620
abnormal response to transplant J:238121
increased osteoclast cell number J:158620
Tg(Col1a1-FGF2*,-Sapphire)203Mmh/Tg(Col1a1-FGF2*,-Sapphire)203Mmh
(involves: FVB/N)
increased osteoclast cell number J:159949
osteoarthritis J:240777
Tg(Col1a1-Runx2)#Pmt/0
(involves: BALB/c * C57BL/6)
increased osteoclast cell number J:167992
Tg(Col1a1-TK*)#Rowe/0
(involves: CD-1)
decreased osteoclast cell number J:112520, J:217781
increased spleen weight J:112520
Tg(Col1a1-tTA)139Niss/0
Tg(tetO-HTR4*D100A)7Niss/0

(FVB/N-Tg(Col1a1-tTA)139Niss Tg(tetO-HTR4*D100A)7Niss)
increased osteoclast cell number J:131617
Tg(Col2a1-cre/ERT2)1Dic/0
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl

(involves: 129 * C57BL/6)
osteoarthritis J:271724
Tg(Col2a1-Fgfr3/GH)BDor/0
(FVB/N-Tg(Col2a1-Fgfr3/GH)BDor)
abnormal osteoclast differentiation J:50292
Tg(Col2a1-Mir140)#Asah/0
(C57BL/6-Tg(Col2a1-Mir140)#Asah)
decreased susceptibility to induced arthritis J:160358
Tg(Col2a1-rtTA,tetO-COMP*)2Jath/0
(C57BL/6-Tg(Col2a1-rtTA,tetO-COMP*)2Jath)
increased inflammatory response J:233238
Tg(Col10a1-Tg*L2263P)1Rpbh/0
(Not Specified)
decreased osteoclast cell number J:154052
Tg(Col10a1-Tg*L2263P)1Rpbh/Tg(Col10a1-Tg*L2263P)1Rpbh
(Not Specified)
decreased osteoclast cell number J:154052
Tg(Comp-tTA)#Yeli/0
Tg(tetO-DDR2)#Yeli/0

(Not Specified)
osteoarthritis J:176308
Tg(Cr2-cre)3Cgn/?
Xrcc4tm1Fwa/Xrcc4tm2Fwa

(involves: 129P2/OlaHsd * 129S6/SvEvTac)
abnormal class switch recombination J:150339
Tg(Crh)227.1Pbl/0
(involves: C57BL/6 * SJL)
decreased spleen weight J:92996
decreased thymus weight J:92996
Tg(Csf1r-Tnfsf15,-EGFP)#Targ/0
(involves: C57BL/6)
increased interferon-gamma secretion J:169462
small intestinal inflammation J:169462
Tg(CSF2)2Ygy/0
Tg(IL3)1Ygy/0
Tg(KITLG)3Ygy/0

(C.Cg-Tg(CSF2)2Ygy Tg(IL3)1Ygy Tg(KITLG)3Ygy)
abnormal response to transplant J:107052
decreased susceptibility to graft versus host disease J:107052
Tg(CSTG-NPM1/RARA)#Sjch/0
(involves: C57BL/6)
enlarged spleen J:55196
increased spleen red pulp amount J:55196
Tg(CTSG-NUMA1/RARA)#Skr/0
(involves: C57BL/6)
abnormal spleen morphology J:88103
abnormal spleen red pulp morphology J:88103
enlarged spleen J:88103
increased granulocyte number J:88103
increased leukocyte cell number J:88103
increased neutrophil cell number J:88103
increased spleen germinal center size J:88103
increased spleen white pulp amount J:88103
Tg(CTSG-PML/RARA)135Ley/?
(Not Specified)
abnormal leukocyte cell number J:77881
abnormal spleen red pulp morphology J:77881
enlarged spleen J:77881
spleen hyperplasia J:77881
Tg(CTSG-PML/RARA)135Ley/?
(involves: C3H * C57BL/6)
abnormal spleen red pulp morphology J:59080
enlarged spleen J:59080
immune system phenotype J:59080
increased leukocyte cell number J:59080
Tg(CTSG-PML/RARA)135Ley/0
Tg(CTSG-RARA/PML)#Ley/0

(involves: C3H * C57BL/6)
abnormal spleen red pulp morphology J:59080
enlarged spleen J:59080
immune system phenotype J:59080
increased leukocyte cell number J:59080
Tg(CTSG-PML/RARA)135Ley/0
Wbcc1SWR/J/?

(involves: C3H/HeJ * C57BL/6J * SWR/J)
decreased leukocyte cell number J:139159
Tg(CTSG-PML/RARA)135Ley/0
Wbcc2SWR/J/?

(involves: C3H/HeJ * C57BL/6J * SWR/J)
increased leukocyte cell number J:139159
Tg(CTSG-PML/RARA)135Ley/0
Wbcc3SWR/J/?

(involves: C3H/HeJ * C57BL/6J * SWR/J)
increased leukocyte cell number J:139159
Tg(CTSG-PML/RARA)6179Ppp/0
(Not Specified)
abnormal myelopoiesis J:40373
increased granulocyte number J:40373
increased leukocyte cell number J:40373
Tg(CTSG-PML/RARA)#Ppp/0
(Not Specified)
abnormal myelopoiesis J:78201, J:40373
increased granulocyte number J:40373
increased leukocyte cell number J:40373
Tg(CTSG-RARA/ZBTB16)#Ppp/0
(Not Specified)
abnormal myelopoiesis J:65878
enlarged spleen J:65878
myeloid hyperplasia J:65878
Tg(CTSG-RARA/ZBTB16)#Ppp/0
Tg(CTSG-ZBTB16/RARA)#Ppp/0

(Not Specified)
abnormal myelopoiesis J:65878
increased leukocyte cell number J:65878
Tg(CTSG-ZBTB16/RARA)#Ppp/0
(Not Specified)
abnormal myelopoiesis J:78201
increased leukocyte cell number J:65878, J:78201
Tg(CTSG-ZBTB16/RARA)#Sjch/0
(involves: C57BL/6)
abnormal myelopoiesis J:55196
abnormal spleen morphology J:55196
abnormal spleen red pulp morphology J:55196
enlarged spleen J:55196
increased leukocyte cell number J:55196
myeloid hyperplasia J:55196
Tg(CYP1A1-PPARD)#Jfoe/0
(involves: C57BL/6J * CBA)
increased T cell proliferation J:158907
skin inflammation J:158907
Tg(Dct-Grm1)ESzc/0
(involves: C57BL/6J)
enlarged inguinal lymph nodes J:83183
enlarged submandibular lymph nodes J:83183
Tg(DMD-APP*)7Neve/0
(involves: C57BL/6 * SJL)
abnormal microglial cell morphology J:100978
Tg(DMD-APP*)18Neve/0
(involves: C57BL/6 * SJL)
abnormal microglial cell morphology J:100978
Tg(DO11.10)10Dlo/?
(involves: BALB/c * C3H * C57BL/6)
abnormal thymus physiology J:70572
decreased CD4-positive, alpha-beta T cell number J:70572
decreased double-positive T cell number J:70572
Tg(DO11.10)10Dlo/0
Crlf2tm1Wjl/Crlf2tm1Wjl

(involves: 129 * BALB/c * C3H * C57BL/6)
decreased inflammatory response J:107431
Tg(DO11.10)10Dlo/?
Toxtm1.1Kay/Toxtm1.1Kay

(involves: 129S/Sv * BALB/c * C3H * C57BL/6)
arrested T cell differentiation J:131287
decreased T cell number J:131287
Tg(DPP4)2Nnag/0
(B6.Cg-Tg(DPP4)2Nnag)
abnormal cytokine level J:286321
increased susceptibility to Coronaviridae infection J:286321
lung inflammation J:286321
Tg(DPP4)2Nnag/0
Tmprss2tm1(KOMP)Vlcg/Tmprss2tm1(KOMP)Vlcg

(involves: C57BL/6NCr * C57BL/6NTac * DBA)
abnormal cytokine secretion J:283077
decreased susceptibility to Coronaviridae infection J:283077
Tg(DUX4*)1Maar/?
(involves: C57BL/6J * CBA/J)
increased incidence of corneal inflammation J:195481
Tg(ED-L2-IL1RN/IL1B)#Tcw/?
(B6.Cg-Tg(ED-L2-IL1RN/IL1B)#Tcw)
abnormal interleukin level J:180282
enlarged spleen J:180282
esophageal inflammation J:180282
increased circulating interleukin-6 level J:180282
increased inflammatory response J:180282
Tg(EEF1A1-SHC1*)1Ravi/?
Tg(Lck-cre)1Cwi/?

(involves: 129 * C57BL/6)
abnormal double-negative T cell morphology J:78180
decreased double-positive T cell number J:78180
decreased single-positive T cell number J:78180
thymus hypoplasia J:78180
Tg(EIF1AX-Il31ra)1Jagr/0
(involves: C3H * C57BL/6)
abnormal immune system physiology J:91124
abnormal leukopoiesis J:91124
conjunctivitis J:91124
cutaneous mastocytosis J:91124
decreased T cell number J:91124
dermatitis J:91124
enlarged lymph nodes J:91124
increased activated T cell number J:91124
increased B cell number J:91124
increased memory T cell number J:91124
Tg(Ela1-TAg)18Bri/0
(involves: C57BL/6 * SJL)
pancreas inflammation J:107545
Tg(Ela1-TAg*)79Mjt/0
Tg(MUC1)79.24Gend/0

(involves: C57BL/6 * DBA/2)
immune system phenotype J:64570
Tg(Ela2a-Prss1*,-GFP)1Dbs/0
(C57BL/6-Tg(Ela2a-Prss1*,-GFP)1Dbs)
chronic pancreas inflammation J:144663
increased susceptibility to induced pancreatitis J:144663
Tg(Ela-KRAS*G12D)9Eps/0
(involves: C57BL/6 * FVB)
increased regulatory T cell number J:231759
pancreas inflammation J:231759
Tg(Ela-KRAS*G12D)9Eps/0
Tg(Mt1-TGFBR2*)AM3Epb/0

(involves: C57BL/6 * FVB)
increased regulatory T cell number J:231759
pancreas inflammation J:231759
Tg(Ela-KRAS*G12D)9Eps/0
Tgfbr1tm1Bopa/Tgfbr1+

(involves: 129S1/SvImJ * C57BL/6 * FVB)
increased CD8-positive, alpha-beta T cell number J:231759
Tg(Emu-FGFR3)A5Wmk/0
(FVB/N-Tg(Emu-FGFR3)A5Wmk)
lymphoid hyperplasia J:160845
Tg(Emu-FGFR3)D3Wmk/0
(FVB/N-Tg(Emu-FGFR3)D3Wmk)
lymphoid hyperplasia J:160845
Tg(Emu-Pim1)64aBrn/0
(involves: C57BL/6LiA * CBA)
enlarged lymph nodes J:79624
enlarged spleen J:79624
enlarged thymus J:79624
Tg(Emu-TXLNA)1Amjr/0
(B6.Cg-Tg(Emu-TXLNA)1Amjr)
abnormal B cell physiology J:117018
enhanced humoral immune response J:145185
enlarged spleen J:117018
increased autoantibody level J:117018
increased B cell number J:117018
increased B-1 B cell number J:117018
increased B-2 B cell number J:117018
increased circulating interferon-alpha level J:117018
increased germinal center B cell number J:117018
increased IgA level J:117018
increased IgG2a level J:117018
increased IgM level J:117018
increased immunoglobulin level J:117018
increased marginal zone B cell number J:117018
increased plasma cell number J:117018
increased susceptibility to autoimmune disorder J:117018, J:145185
interstitial pneumonia J:145185
kidney inflammation J:117018
lacrimal gland inflammation J:145185
lymphoid hyperplasia J:117018
parotid gland inflammation J:145185
salivary gland inflammation J:117018, J:145185
submandibular gland inflammation J:145185
Tg(Emu-Zfp521)1Homy/0
(Not Specified)
abnormal B cell differentiation J:160392
increased B cell number J:160392
Tg(EmuSR-HDAC9)1468Kpet/0
(involves: C57BL/6 * CBA)
abnormal lymphocyte physiology J:237420
abnormal spleen marginal zone morphology J:237420
enlarged spleen J:237420
increased B cell number J:237420
increased B cell proliferation J:237420
Tg(EmuSR-tTa)83Bop/0
Tg(IghMyc)22Bri/0
Tg(tetO-RNAi:Trp53)ASlowe/0

(involves: C57BL * C57BL/6 * FVB/N * SJL)
enlarged spleen J:123006
Tg(EmuSR-tTa)83Bop/Tg(EmuSR-tTa)83Bop
Tg(tetO-NPM1/ALK,-luc)2Gde/0

(involves: FVB/N)
enlarged lymph nodes J:160236
enlarged spleen J:160236
Tg(EmuSR-tTa)83Bop/Tg(EmuSR-tTa)83Bop
Tg(tetO-TPM3/ALK,-luc)2Gde/0

(involves: FVB/N)
enlarged lymph nodes J:160236
enlarged spleen J:160236
Tg(Eno2-Hgf)1Tnak/0
Tg(SOD1*G93A)dl1Gur/0

(involves: C57BL/6 * C57BL/6J * SJL/J)
microgliosis J:128738
Tg(Eno2-Hmox1)2Main/Tg(Eno2-Hmox1)2Main
(involves: C57BL/6J)
enlarged spleen J:120240
Tg(EPO33)72Ptc/0
(involves: C57BL/6J * SJL/J)
enlarged spleen J:92650
Tg(F2RL1)1Mslb/0
(involves: FVB/NCrl)
increased inflammatory response J:79757
respiratory system inflammation J:79757
Tg(Fabp1-cre)1Jig/0
Vhltm1Jae/Vhltm1Jae

(involves: 129S4/SvJae * BALB/c * FVB/N)
decreased susceptibility to induced colitis J:93476
Tg(Fabp2-Arg1)1Wla/Tg(Fabp2-Arg1)1Wla
(involves: FVB)
abnormal B cell differentiation J:80204
abnormal Peyer's patch morphology J:80204, J:80556
decreased B cell number J:80204
decreased IgM level J:80204
decreased Peyer's patch number J:80556
decreased pre-B cell number J:80204
decreased spleen B cell follicle number J:80204
decreased spleen weight J:80556
decreased transitional stage B cell number J:80204
small Peyer's patches J:80556
small spleen J:80204
Tg(Fabp4-Angptl2)5Yo/0
(involves: C57BL/6)
abnormal macrophage chemotaxis J:152387
chronic inflammation J:152387
white adipose tissue inflammation J:152387
Tg(Fabp4-Apol6)#Hsul/0
(C57BL/6J-Tg(Fabp4-Apol6)#Hsul)
white adipose tissue inflammation J:344362
Tg(Fabp4-Phb*Y114F)#Smis/0
(Not Specified)
abnormal circulating chemokine level J:227976
abnormal circulating cytokine level J:227976
abnormal lymph node morphology J:227976
abnormal spleen morphology J:227976
enlarged lymph nodes J:227976
enlarged spleen J:227976
increased lymphocyte cell number J:227976
Tg(FCGR2A)11Mkz/0
Tg(PF4)#Zcy/0

(involves: C57BL/6 * SJL)
increased acute inflammation J:72220
Tg(FCGR2A)11Mkz/Tg(FCGR2A)11Mkz
(involves: C57BL/6 * SJL)
abnormal macrophage physiology J:136516
arthritis J:136516
glomerulonephritis J:136516
increased anti-histone antibody level J:136516
increased IgG2a level J:136516
increased susceptibility to induced arthritis J:136516
increased tumor necrosis factor secretion J:136516
interstitial pneumonia J:136516
Tg(Fga,Fgb,Fgg)1Unc/?
(C57BL/6-Tg(Fga,Fgb,Fgg)1Unc)
increased circulating fibrinogen level J:118353
Tg(Fli1)1Ber/0
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1)
increased thymocyte number J:33052
Tg(FOXJ1-ACE2)1Rba/0
(involves: C3H * C57BL/6)
decreased lymphocyte cell number J:288386
increased susceptibility to Coronaviridae infection J:287092, J:288386
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:287092, J:288386
interstitial pneumonia J:288386
Tg(Foxp3-HBEGF/EGFP)23.2Spar/0
(involves: C57BL/6NCrl)
decreased regulatory T cell number J:125295
enlarged lymph nodes J:125295
enlarged spleen J:125295
immune system phenotype J:125295
increased inflammatory response J:125295
increased spleen red pulp amount J:125295
increased spleen white pulp amount J:125295
increased susceptibility to type IV hypersensitivity reaction J:125295
insulitis J:125295
lung inflammation J:125295
lymph node hyperplasia J:125295
skin inflammation J:125295
Tg(Gfap-gp120)2Lms/0
(involves: C57BL/6 * SJL)
abnormal microglial cell morphology J:146427
microgliosis J:146427
Tg(Gfap-gp120)10Lms/0
(involves: C57BL/6 * SJL)
microgliosis J:146427
Tg(Gfap-Ifna1)12Ilc/0
(involves: BALB/c * C57BL/6J)
CNS inflammation J:68811
decreased susceptibility to Riboviria infection J:68811
decreased susceptibility to Riboviria infection induced morbidity/mortality J:68811
meningoencephalitis J:68811
Tg(Gfap-Ifna1)39Ilc/0
(involves: BALB/c * C57BL/6J)
CNS inflammation J:68811
meningoencephalitis J:68811
Tg(Gfap-Il6)G16Lms/0
Tg(Gfap-lacZ)1Lms/0

(involves: C57BL/6J * SJL)
immune system phenotype J:125549
Tg(Gfap-Il6)G369Lms/0
(involves: C57BL/6J * SJL)
immune system phenotype J:125549
Tg(Gfap-rtTA,tetO-MAOB,-lacZ)1Jkan/0
(involves: C57BL/6)
abnormal microglial cell activation J:132679
abnormal microglial cell morphology J:132679
Tg(Gfap-TGFB1)64Lms/0
(involves: BALB/c * SJL)
immune system phenotype J:27781
Tg(Gfap-TGFB1)64Lms/Tg(Gfap-TGFB1)64Lms
(involves: BALB/c * SJL)
immune system phenotype J:27781
Tg(Gfap-TK)7.1Mvs/0
(involves: C57BL/10 * CBA * CFLP)
abnormal inflammatory response J:104241
brain inflammation J:113202
increased neutrophil cell number J:104241
small intestinal inflammation J:104241
Tg(Gfap-TNF*)K21Gkl/0
(involves: C57BL/6 * CBA)
CNS inflammation J:106592
Tg(GFAP-tTA)78Pop/0
Tg(tetO-Ifng)184Pop/0

(B6.Cg-Tg(GFAP-tTA)78Pop Tg(tetO-Ifng)184Pop)
abnormal interferon-gamma secretion J:109838
CNS inflammation J:109838
Tg(GNB1L,TBX1,GP1BB,SEPT5)23Bem/0
(either: FVB-Tg(GNB1L,TBX1,GP1BB,SEPT5)23Bem or (involves: C57BL/6 * FVB))
abnormal thymus development J:67796
abnormal thymus lobule morphology J:67796
decreased thymocyte number J:67796
thymus hypoplasia J:67796
Tg(H2-Aa)26Dim/?
Tg(H2-Ab1)62Dim/?

(B6.Cg-Tg(H2-Aa)26Dim Tg(H2-Ab1)62Dim)
abnormal antigen presentation via MHC class II J:110897
abnormal level of surface class II molecules J:110897
immune system phenotype J:110897
increased immunoglobulin level J:110897
Tg(H2-Aa)26Dim/?
Tg(H2-Ab1)62Dim/?

(SJL.Cg-Tg(H2-Aa)26Dim Tg(H2-Ab1)62Dim)
abnormal level of surface class II molecules J:110897
immune system phenotype J:110897
Tg(H2-D-Il15)3304Clgr/?
(FVB/N-Tg(H2-D-Il15)3304Clgr)
abnormal inflammatory response J:67478
abnormal lymphocyte physiology J:67478
abnormal T cell morphology J:67478
abnormal T cell subpopulation ratio J:67478
dermatitis J:67478
enlarged lymph nodes J:67478
enlarged spleen J:67478
increased lymphocyte cell number J:67478
increased memory T cell number J:67478
increased NK cell number J:67478
increased spleen white pulp amount J:67478
Tg(H2-Db)2Bujf/0
(FVB/NPas-Tg(H2-Db)2Bujf)
decreased susceptibility to Picornaviridae infection J:18556
Tg(H2-Ea)16Dim/?
(involves: C57BL/6 * SJL)
increased immunoglobulin level J:111128
Tg(H2-Ea-G6pc2)69Tkay/?
(NOD-Tg(H2-Ea-G6pc2)69Tkay)
abnormal CD4-positive, alpha-beta T cell physiology J:117352
abnormal CD8-positive, alpha beta T cell morphology J:117352
abnormal immune tolerance J:117352
decreased T cell proliferation J:117352
increased anti-insulin autoantibody level J:117352
increased susceptibility to autoimmune diabetes J:117352
insulitis J:117352
Tg(H2-Ea-HA)HACIIAjca/0
Tg(Tcra/Tcrb)1Vbo/0

(C.Cg-Tg(H2-Ea-HA)HACIIAjca Tg(Tcra/Tcrb)1Vbo)
abnormal CD4-positive, alpha beta T cell morphology J:209872
abnormal circulating cytokine level J:209872
arthritis J:209872
heart inflammation J:209872
increased circulating interleukin-6 level J:209872
increased IgG level J:209872
joint inflammation J:209872
kidney inflammation J:209872
Tg(H2-Ea-HA)HACIIAjca/0
Tg(TcraS106-1,TcrbS106-1)TS1SWAjca/0

(C.Cg-Tg(H2-Ea-HA)HACIIAjca Tg(TcraS106-1,TcrbS106-1)TS1SWAjca)
abnormal CD4-positive, alpha beta T cell morphology J:209872
abnormal CD4-positive, alpha-beta T cell physiology J:209872
abnormal circulating cytokine level J:209872
arthritis J:209872
decreased circulating interleukin-6 level J:209872
enlarged lymph nodes J:209872
immune system phenotype J:209872
increased circulating interleukin-17 level J:209872
increased IgG level J:209872
joint inflammation J:209872
Tg(H2-Ea-Il7)10Rhdr/0
(involves: C57BL/6)
abnormal B cell morphology J:81133
abnormal double-negative T cell morphology J:81133
Tg(H2-Ea-Il7)10Rhdr/0
(involves: C57BL/6 * DBA/2)
increased pre-B cell number J:171924
increased pro-B cell number J:171924
Tg(H2-Ea-Ins2)1Wehi/0
(NOD/ShiLtJWehi-Tg(H2-Ea-Ins2)1Wehi)
abnormal T cell proliferation J:100232
immune system phenotype J:100232
salivary gland inflammation J:100232
Tg(H2-Ea-Ins2)1Wehi/Tg(H2-Ea-Ins2)1Wehi
(NOD/ShiLtJWehi-Tg(H2-Ea-Ins2)1Wehi)
abnormal CD8-positive, alpha beta T cell morphology J:117352
decreased anti-insulin autoantibody level J:117352
decreased T cell proliferation J:117352
immune system phenotype J:117352
Tg(H2-Ea-LACK)1Ngkh/0
(C.Cg-Tg(H2-Ea-LACK)1Ngkh)
abnormal immune system physiology J:181384
abnormal T-helper 1 physiology J:181384
abnormal T-helper 2 physiology J:181384
decreased susceptibility to parasitic infection J:181384
decreased susceptibility to parasitic infection induced morbidity/mortality J:181384
decreased T-helper 2 cell number J:181384
increased T-helper 1 cell number J:181384
Tg(H2-Ea-Tnfsf9)16Lpc/0
(involves: C57BL/6)
abnormal B cell physiology J:132372
abnormal lymph node B cell domain morphology J:132372
decreased B cell number J:132372
decreased IgG level J:132372
decreased spleen B cell follicle number J:132372
enlarged spleen J:132372
increased granulocyte number J:132372
increased lymphocyte cell number J:132372
increased macrophage cell number J:132372
increased memory T cell number J:145439
increased NK cell number J:132372
spleen hyperplasia J:132372
Tg(H2-Ead)5Lt/0
(NOD/ShiLt-Tg(H2-Ead)5Lt)
autoimmune response J:36435
decreased interferon-gamma secretion J:36435
decreased susceptibility to autoimmune diabetes J:36435
increased interleukin-4 secretion J:36435
periinsulitis J:36435
Tg(H2-Ead)12Lt/0
(NOD/ShiLt-Tg(H2-Ead)12Lt)
autoimmune response J:36435
decreased interferon-gamma secretion J:36435
decreased susceptibility to autoimmune diabetes J:36435
increased interleukin-4 secretion J:36435
insulitis J:36435
Tg(H2-K1-HLA-A*)28Mpla/0
(B10.Cg-Tg(H2-K1-HLA-A*)28Mpla)
choroid inflammation J:67871
eye inflammation J:67871
Tg(H2-K-BCL2)1Josd/0
(involves: C57BL/6 * C57BL/Ka * C3H)
abnormal lymph organ size J:80894
enlarged lymph nodes J:80894
enlarged spleen J:80894
enlarged thymus J:80894
increased leukocyte cell number J:80894
Tg(H2-K-Cd86)7All/0
(involves: C57BL/6J * CBA)
abnormal B cell differentiation J:112475
decreased B cell number J:112475
increased CD4-positive, alpha-beta T cell number J:112475
increased CD8-positive, alpha-beta T cell number J:112475
Tg(H2-K-Cd86)7All/0
(B6.Cg-Tg(H2-K-Cd86)7All)
abnormal inflammatory response J:112266
decreased B cell number J:112266
decreased CD4-positive, alpha-beta T cell number J:112266
increased CD8-positive, alpha-beta T cell number J:112266
increased T cell number J:112266
lymph node hyperplasia J:112266
lymphoid hyperplasia J:112266
Tg(H2-K-Cd86)7All/0
(involves: BALB/c * C57BL/6 * CBA)
increased splenocyte number J:112266
lymph node hyperplasia J:112266
spleen hyperplasia J:112266
Tg(H2-K-Cd86)27All/0
(involves: C57BL/6J * CBA)
abnormal B cell differentiation J:112475
decreased B cell number J:112475
Tg(H2-K-Cd86)31All/0
(involves: C57BL/6J * CBA)
increased CD4-positive, alpha-beta T cell number J:112475
increased CD8-positive, alpha-beta T cell number J:112475
Tg(H2-K-DUSP5)21Wjl/0
(involves: C57BL/6J * CBA)
abnormal T cell number J:138077
decreased single-positive T cell number J:138077
decreased T cell proliferation J:138077
dermatitis J:138077
increased CD4-positive, alpha-beta T cell number J:138077
increased CD8-positive, alpha-beta T cell number J:138077
increased double-positive T cell number J:138077
increased plasma cell number J:138077
increased single-positive T cell number J:138077
skin inflammation J:138077
Tg(H2-K-Fosl1)1Wag/0
(involves: C57BL/6 * CBA)
enlarged spleen J:64494
Tg(H2-K-Fosl2,-EGFP)13Wag/0
(either: 129.Cg-Tg(H2-K-Fosl2,-EGFP)13Wag or B6.Cg-Tg(H2-K-Fosl2,-EGFP)13Wag)
thymus fibrosis J:139032
Tg(H2-K-Fosl2,-EGFP)13Wag/0
(B6.Cg-Tg(H2-K-Fosl2,-EGFP)13Wag)
lung inflammation J:238723
Tg(H2-K-HLA-G,B2M)1Alm/0
(CBA/Ca-Tg(H2-K-HLA-G,B2M)1Alm/CmwJ)
abnormal cytotoxic T cell physiology J:140016
increased T cell proliferation J:140016
Tg(H2-K-Hmga1)#Lmsr/0
(involves: C57BL/6 * SJL)
increased leukocyte cell number J:90252
Tg(H2-K-IL6)2Srj/0
(B6.Cg-Tg(H2-K-IL6)2Srj)
abnormal granulocyte morphology J:185153
abnormal lymph node germinal center morphology J:185153
abnormal lymph node morphology J:185153
abnormal spleen germinal center morphology J:185153
abnormal spleen red pulp morphology J:185153
enlarged lymph nodes J:185153
enlarged spleen J:185153
increased IgG level J:185153
increased plasma cell number J:185153
Tg(H2-K-MC159/EGFP)13Fkmc/0
(involves: C57BL/6)
abnormal lymphopoiesis J:138050
decreased B cell apoptosis J:138050
decreased T cell apoptosis J:138050
enlarged spleen J:138050
immune system phenotype J:138050
increased B cell proliferation J:138050
increased follicular B cell number J:138050
Tg(H2-K-MC159/EGFP)13Fkmc/Tg(H2-K-MC159/EGFP)13Fkmc
(involves: C57BL/6)
increased anti-double stranded DNA antibody level J:138050
increased double-negative T cell number J:138050
increased IgG2b level J:138050
increased T cell number J:138050
Tg(H2-K-TcrbP14)128Mak/?
(involves: C57BL/6 * C57L * DBA/2)
abnormal CD8-positive, alpha-beta T cell differentiation J:111265
abnormal T cell clonal deletion J:111265
abnormal T cell differentiation J:111265
increased CD8-positive, alpha-beta T cell number J:111265
Tg(H2-Kb-IL21)5Wjl/0
(involves: 129)
abnormal B cell differentiation J:93740
abnormal class switch recombination J:93740
decreased follicular B cell number J:93740
decreased marginal zone B cell number J:93740
decreased mature B cell number J:93740
decreased transitional stage T2 B cell number J:93740
increased B cell apoptosis J:93740
increased IgG1 level J:93740
increased IgM level J:93740
increased immature B cell number J:93740
increased transitional stage T1 B cell number J:93740
Tg(H2-Kb-Jak2*V617F)2Shmd/0
(involves: C57BL/6 * DBA/2)
abnormal spleen morphology J:130189
enlarged spleen J:130189
increased leukocyte cell number J:130189
increased neutrophil cell number J:130189
increased spleen red pulp amount J:130189
increased spleen weight J:130189
myeloid hyperplasia J:130189
spleen fibrosis J:130189
Tg(H2-Kb-Tcra,-Tcrb)1640Kurs/0
(SJL.FVB-Tg(H2-Kb-Tcra,-Tcrb)1640Kurs)
abnormal cytokine level J:149511
brain inflammation J:149511
CNS inflammation J:149511
increased autoantibody level J:149511
increased susceptibility to experimental autoimmune encephalomyelitis J:149511
increased T-helper 1 cell number J:149511
increased T-helper 17 cell number J:149511
Tg(H2-L-IL6)1Kish/Tg(H2-L-IL6)1Kish
(C57BL/6-Tg(H2-L-IL6)1Kish)
abnormal myelopoiesis J:128016
enlarged lymph nodes J:128016, J:138762
enlarged spleen J:128016, J:138762
glomerulonephritis J:128016, J:138762
increased IgG1 level J:128016
increased monocyte cell number J:128016
increased neutrophil cell number J:128016
increased plasma cell number J:128016, J:138762
Tg(H2-L-IL6)40Csk/0
(involves: C57BL/6)
enlarged lymph nodes J:207264
enlarged spleen J:207264
increased spleen weight J:207264
Tg(H2-L-IL6)46Kish/Tg(H2-L-IL6)46Kish
(C57BL/6-Tg(H2-L-IL6)46Kish)
enlarged axillary lymph nodes J:40405
enlarged mesenteric lymph nodes J:40405
glomerulonephritis J:40405
increased immunoglobulin level J:40405
increased plasma cell number J:40405
Tg(H2-L-IL6)46Kish/Tg(H2-L-IL6)46Kish
(involves: BALB/c * C57BL/6)
abnormal immune system organ morphology J:40405
abnormal lymph node morphology J:40405
enlarged mesenteric lymph nodes J:40405
increased IgA level J:40405
increased immunoglobulin level J:40405
Tg(H2-L-IL6)46Kish/Tg(H2-L-IL6)46Kish
(C.B6-Tg(H2-L-IL6)46Kish)
abnormal spleen trabecular artery morphology J:177820
abnormal spleen trabecular vein morphology J:177820
enlarged spleen J:177820
increased IgG1 level J:74377
increased IgG2b level J:74377
increased IgG level J:74377
Tg(H2-Ld)LoxNibl/0
(C57BL/6-Tg(H2-Ld)LoxNibl)
decreased susceptibility to parasitic infection induced morbidity/mortality J:284394
increased response to antigen J:284394
Tg(H2KePCC)2403Stoe/?
(involves: C57BL/6 * SJL)
abnormal immune tolerance J:92997
Tg(H2KePCC)2403Stoe/?
Tg(TcraTcrbAD10)1Hed/?

(involves: C57BL/6 * SJL)
abnormal immune tolerance J:92997
abnormal T cell anergy J:92997
decreased CD4-positive, alpha-beta T cell number J:92997
Tg(H2KmPCC)2939Stoe/?
(involves: C57BL/6 * SJL)
abnormal immune tolerance J:92997
Tg(H2KmPCC)2939Stoe/0
Tg(Tcra2B4)1Mmd/0
Tg(Tcrb2B4)1Mmd/0

(involves: C3H/HeJ * C57BL/6 * SJL)
abnormal T cell differentiation J:50143
decreased T cell proliferation J:50143
decreased thymocyte number J:50143
Tg(H2KmPCC)2939Stoe/?
Tg(TcrAND)53Hed/?

(involves: C57BL/6 * SJL)
abnormal immune tolerance J:92997
abnormal T cell anergy J:92997
decreased CD4-positive, alpha-beta T cell number J:92997
Tg(H2KmPCC)2939Stoe/?
Tg(TcraTcrbAD10)1Hed/?

(involves: C57BL/6 * SJL)
abnormal immune tolerance J:92997
abnormal T cell anergy J:92997
decreased CD4-positive, alpha-beta T cell number J:92997
Tg(HBB-Myc)#Cos/0
(involves: C57BL/6J * CBA/J)
abnormal immune system organ morphology J:276641
kidney inflammation J:276641
Tg(HBV)10Imeg/0
(involves: C57BL/6)
abnormal cytokine secretion J:95283
abnormal dendritic cell physiology J:95283
Tg(HBVX*,-Myc)#Skp/Tg(HBVX*,-Myc)#Skp
(Not Specified)
increased macrophage cell number J:81098
Tg(HCRT-tTA)1Ahky/0
Tg(tetO-DTA)1Gfi/0

(B6.Cg-Tg(HCRT-tTA)1Ahky Tg(tetO-DTA)1Gfi)
increased microglial cell activation J:211045
Tg(HIV)26Aln/0
(involves: FVB/N)
kidney inflammation J:90297
myositis J:90297
uveitis J:136652
Tg(HLA-A2/H2-K)1Scr/?
(involves: C57BL/6)
abnormal cytotoxic T cell physiology J:127813
Tg(HLA-A/H2-D/B2M)1Dvs/0
(NOD/ShiLtDvs-Tg(HLA-A/H2-D/B2M)1Dvs)
increased susceptibility to autoimmune diabetes J:121685
Tg(HLA-B27)1Trg/0
(involves: C57BL/6 * SJL/J)
immune system phenotype J:74451
Tg(HLA-B27)30-4Trg/?
(involves: C57BL/6J * NOD)
decreased susceptibility to autoimmune diabetes J:109851
Tg(HLA-DQA1,HLA-DQB1)1Dv/0
Tg(Ins2-CD80)3B7Flv/0

(B6.Cg-Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv)
decreased susceptibility to autoimmune diabetes J:59245
Tg(HLA-DR2)#Lfug/0
Tg(TCROb.1A12)#Lfug/0

(involves: C57BL/6 * DBA/2)
CNS inflammation J:134764
increased susceptibility to experimental autoimmune encephalomyelitis J:134764
Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz/Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dmz
(involves: C57BL/6 * C57BL/10Sn * SJL/J)
abnormal T cell physiology J:108635
increased autoantibody level J:108635
increased susceptibility to induced arthritis J:108635
Tg(Hmgcr-MX1)LStae/Tg(Hmgcr-MX1)LStae
(involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL)
decreased susceptibility to Orthomyxoviridae infection J:119783
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:119783
Tg(HTT*)NXwy/0
(involves: FVB/NJ)
CNS inflammation J:219890
Tg(ICAM1)4Grom/?
(involves: BALB/cAnNTac)
increased susceptibility to Picornaviridae infection J:92607
Tg(Igh3H9)41Mwg/?
(involves: C57BL/6 * SJL)
abnormal B cell differentiation J:119625
decreased IgD level J:119625
increased anti-single stranded DNA antibody level J:119625
Tg(Igh*-Mir125b-1)5Toki/0
(Not Specified)
enlarged spleen J:178816
Tg(Igh*-Mir125b-1)116Toki/0
(Not Specified)
decreased B cell apoptosis J:178816
enlarged spleen J:178816
increased B cell number J:178816
Tg(Igh-3/Igh-6VD93)1241Ust/?
(C57BL/6-Tg(Igh-3/Igh-6VD93)1241Ust)
abnormal B cell morphology J:135209
decreased pre-B cell number J:135209
Tg(Igh-3VD93)343Ust/?
(involves: C57BL/6 * SJL)
abnormal B cell morphology J:135209
decreased pre-B cell number J:135209
Tg(Igh-6-Cd80)1Gjf/0
(involves: FVB)
abnormal CD4-positive, alpha-beta T cell physiology J:44271
abnormal humoral immune response J:112474
abnormal T cell activation J:44271
decreased B cell number J:44271
decreased immunoglobulin level J:112474
Tg(Igh-6-Cd80)1Gjf/0
(B6.Cg-Tg(Igh-6-Cd80)1Gjf)
abnormal T cell number J:112266
Tg(Igh-6-Cd80)1Gjf/0
(NOD.FVB-Tg(Igh-6-Cd80)1Gjf/JbsJ)
abnormal B cell activation J:131077
abnormal CD8-positive, alpha-beta T cell physiology J:131077
abnormal level of surface class II molecules J:131077
decreased B cell number J:131077
decreased B-2 B cell number J:131077
decreased follicular B cell number J:131077
decreased IgG1 level J:131077
decreased IgG2b level J:131077
decreased IgG3 level J:131077
decreased IgM level J:131077
decreased immature B cell number J:131077
decreased immunoglobulin level J:131077
decreased mature B cell number J:131077
decreased susceptibility to autoimmune diabetes J:131077
insulitis J:131077
Tg(Igh-6-Cd86)1Akab/0
(involves: FVB)
abnormal CD4-positive, alpha-beta T cell physiology J:44271
decreased B cell number J:44271
Tg(Igh-6/Igh-V125)2Jwt/0
Tg(Igk-C/Igk-V125)1Jwt/0

(NOD.B6-Tg(Igh-6/Igh-V125)2Jwt Tg(Igk-C/Igk-V125)1Jwt)
abnormal B cell number J:91865
increased susceptibility to autoimmune diabetes J:91865
insulitis J:91865
Tg(Igh-6/Igh-V281)3Jwt/0
(NOD.B6-Tg(Igh-6/Igh-V281)3Jwt)
decreased susceptibility to autoimmune diabetes J:91865
insulitis J:91865
Tg(Igh-Abl1)40Sco/0
(involves: C57BL/6JWehi * SJL/JWehi)
abnormal peripheral lymph node morphology J:78204
enlarged mesenteric lymph nodes J:78204
enlarged spleen J:78204
Tg(Igh-Abl1)40Sco/0
Tg(IghMyc)22Bri/0

(involves: C57BL/6 * C57BL/6JWehi * SJL/J * SJL/JWehi)
enlarged mesenteric lymph nodes J:78204
Tg(Igh-HMGA2)#Cro/0
(FVB/N-Tg(Igh-HMGA2)#Cro)
abnormal splenic cell ratio J:233225
decreased B cell number J:233225
decreased IgG1 level J:233225
decreased IgG2a level J:233225
decreased IgG2b level J:233225
decreased IgG3 level J:233225
decreased response to antigen J:233225
decreased T cell number J:233225
enlarged lymph nodes J:233225
enlarged spleen J:233225
increased circulating interleukin-6 level J:233225
increased circulating tumor necrosis factor level J:233225
increased T cell number J:233225
Tg(Igh-HOX11)11Idd/0
(CD-1)
abnormal immunoglobulin V(D)J recombination J:52782
increased leukocyte cell number J:52782
myeloid hyperplasia J:52782
spleen hyperplasia J:52782
Tg(Igh-Lmp2a)ERlon/0
(involves: C57BL/6 * SJL)
abnormal B cell proliferation J:129571
decreased B cell number J:129571
Tg(Igh-Maf)68Staka/0
(C57BL/6-Tg(Igh-Maf)68Staka)
abnormal spleen morphology J:168074
enlarged spleen J:168074
increased IgG level J:168074
increased IgM level J:168074
increased immunoglobulin level J:168074
increased plasma cell number J:168074
Tg(Igh-Maf)524Staka/0
(involves: C57BL/6 * C57BL/6J * DBA/2)
abnormal spleen morphology J:168074
enlarged spleen J:168074
increased IgG level J:168074
increased IgM level J:168074
increased immunoglobulin level J:168074
increased plasma cell number J:168074
Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
(FVB/N-Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro)
abnormal B cell physiology J:162077
abnormal lymphopoiesis J:162077
abnormal spleen morphology J:162077
decreased IgG1 level J:162077
decreased IgG2a level J:162077
decreased IgG2b level J:162077
enlarged spleen J:162077
increased B cell proliferation J:162077
increased B-1a cell number J:162077
spleen hyperplasia J:162077
Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
Tg(Igh-V186.2-TCL1A)3Cro/0

(involves: C3H * C57BL/6 * FVB/N)
increased B-1a cell number J:162077
spleen hyperplasia J:162077
Tg(Igh-Mir155)8Cro/0
(involves: FVB/N)
abnormal lymphopoiesis J:109591
abnormal spleen B cell follicle morphology J:109591
decreased leukocyte cell number J:109591
decreased spleen white pulp amount J:109591
enlarged spleen J:109591
increased B cell number J:109591
increased B cell proliferation J:109591
increased pre-B cell number J:109591
increased spleen white pulp amount J:109591
intermingled spleen red and white pulp J:109591
Tg(Igh-Mir155)10Cro/0
(involves: FVB/N)
enlarged spleen J:109591
Tg(Igh-Mir210)#aKgcs/Tg(Igh-Mir210)#aKgcs
(B6.Cg-Tg(Igh-Mir210)#aKgcs)
abnormal class switch recombination J:205868
abnormal spleen marginal zone morphology J:205868
decreased IgA level J:205868
decreased IgG1 level J:205868
decreased IgG2a level J:205868
decreased IgG2b level J:205868
decreased IgG3 level J:205868
decreased marginal zone B cell number J:205868
decreased mature B cell number J:205868
decreased pre-B cell number J:205868
decreased pro-B cell number J:205868
immune system phenotype J:205868
increased B-1a cell number J:205868
Tg(Igh-Nfil3)#Kubo/0
(B6.Cg-Tg(Igh-Nfil3)#Kubo)
increased interleukin-3 secretion J:172134
increased interleukin-10 secretion J:172134
increased interleukin-13 secretion J:172134
Tg(Igh-Pim1)1Brn/0
(involves: C57BL/6LiA * CBA)
enlarged lymph nodes J:79624
enlarged spleen J:79624
enlarged thymus J:79624
Tg(Igh-ROR1)1Kip/0
(C57BL/6-Tg(Igh-ROR1)1Kip)
enlarged spleen J:206368
increased lymphocyte cell number J:206368
increased mature B cell number J:206368
Tg(Igh-ROR1)1Kip/0
Tg(Igh-V186.2-TCL1A)3Cro/0

(B6.Cg-Tg(Igh-ROR1)1Kip Tg(Igh-V186.2-TCL1A)3Cro)
enlarged spleen J:206368
increased lymphocyte cell number J:206368
increased mature B cell number J:206368
Tg(Igh-TCL1A)1Ypek/0
(FVB/N-Tg(Igh-TCL1A)1Ypek)
abnormal circulating chemokine level J:160184
abnormal humoral immune response J:160184
abnormal lymphocyte physiology J:160184
decreased IgG1 level J:160184
decreased IgG2a level J:160184
decreased IgG2b level J:160184
decreased IgG3 level J:160184
decreased IgM level J:160184
enlarged spleen J:160184
increased circulating tumor necrosis factor level J:160184
Tg(Igh-V186.2-TCL1A)3Cro/0
(involves: C3H * C57BL/6)
abnormal B cell morphology J:76574
increased marginal zone B cell number J:76574
peritoneal inflammation J:76574
spleen hyperplasia J:76574
Tg(Igh-V-CD40lg)#Tsub/0
(C57BL/6-Tg(Igh-V-CD40lg)#Tsub)
glomerulonephritis J:128824
increased anti-double stranded DNA antibody level J:128824
increased anti-histone antibody level J:128824
increased anti-single stranded DNA antibody level J:128824
Tg(Igh-V-CD40lg)#Tsub/0
(involves: C57BL/6)
abnormal bronchus-associated lymphoid tissue morphology J:89855
colitis J:89855
enlarged lymph nodes J:89855
enlarged spleen J:89855
glomerulonephritis J:89855
increased autoantibody level J:89855
increased IgG level J:89855
increased IgM level J:89855
increased interferon-gamma secretion J:89855
increased splenocyte number J:89855
increased splenocyte proliferation J:89855
Tg(IGH@*)SALed/0
(involves: C57BL/6 * CD-1)
abnormal mature B cell morphology J:131938
Tg(IGH@yH1)2BJkbv/0
(involves: 129P2/OlaHsd)
abnormal B cell morphology J:23827
abnormal immunoglobulin heavy chain V(D)J recombination J:23827
abnormal immunoglobulin level J:23827
Tg(IGH@yH1)2BJkbv/0
Tg(IGK@yK1)9.2CJkbv/0

(involves: 129P2/OlaHsd)
abnormal B cell morphology J:23827
abnormal immunoglobulin level J:23827
Tg(IghelMD4)4Ccg/0
(involves: C3H/HeJ * C57BL/6)
decreased pre-B cell number J:115059
decreased pro-B cell number J:115059
Tg(IghelMD4)4Ccg/0
(involves: C57BL/6)
abnormal B cell activation J:73608
decreased pre-B cell number J:115059
decreased pro-B cell number J:115059
Tg(IghelMD4)4Ccg/0
(C57BL/6-Tg(IghelMD4)4Ccg)
abnormal B cell morphology J:78308, J:109923, J:132538
abnormal B-2 B cell morphology J:132538
abnormal germinal center B cell morphology J:109923
abnormal immature B cell morphology J:109923
abnormal mature B cell morphology J:89156, J:109923
abnormal plasma cell morphology J:109923
abnormal pro-B cell morphology J:109923
increased IgG2b level J:132538
increased IgM level J:78308, J:132538
increased immature B cell number J:78308, J:132538
Tg(IghelMD4)4Ccg/0
Tg(KLK4mHEL)6Ccg/0

(NOD.B6-Tg(IghelMD4)4Ccg Tg(KLK4mHEL)6Ccg/Dvs)
decreased B cell number J:89156
Tg(IghelMD4)4Ccg/0
Tg(KLK4mHEL)6Ccg/0

(C57BL/6-Tg(IghelMD4)4Ccg Tg(KLK4mHEL)6Ccg)
decreased B cell number J:89156
Tg(IghelMD4)4Ccg/?
Tg(KLK4mHEL)6Ccg/?

(involves: C57BL/6)
arrested B cell differentiation J:78307
decreased mature B cell number J:78307
increased immature B cell number J:78307
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0

(NOD.B6-Tg(IghelMD4)4Ccg Tg(ML5sHEL)5Ccg/Dvs)
abnormal B cell anergy J:89156
abnormal B cell clonal deletion J:89156
abnormal B cell morphology J:89156
decreased IgM level J:89156
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0

(C57BL/6-Tg(IghelMD4)4Ccg Tg(ML5sHEL)5Ccg)
abnormal B cell anergy J:89156, J:78308
abnormal central B cell anergy J:109923
abnormal germinal center B cell morphology J:109923
abnormal immature B cell morphology J:109923
abnormal mature B cell morphology J:109923
abnormal plasma cell morphology J:109923
abnormal pro-B cell morphology J:109923
abnormal spleen B cell follicle morphology J:109923
decreased B cell number J:89156
decreased IgM level J:89156, J:78308
Tg(IghelMD4)4Ccg/0
Tg(ML5sHEL)5Ccg/0

(involves: C57BL/6)
abnormal B cell anergy J:73608, J:132538
abnormal B cell physiology J:76134
abnormal spleen primary B follicle morphology J:76134
decreased B cell number J:76134
decreased marginal zone B cell number J:132538
Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
(NOD.B6-Tg(IghelMD4)4Ccg/DvsJ)
abnormal mature B cell morphology J:80859, J:89156
abnormal T cell proliferation J:80859
decreased CD8-positive, alpha-beta T cell number J:80859
increased susceptibility to autoimmune diabetes J:80859
Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
(involves: C57BL/6)
decreased pre-B cell number J:171924
decreased pro-B cell number J:171924
Tg(IghH280)48Dvs/?
(NOD/ShiLtDvs-Tg(IghH280)48Dvs/J)
increased susceptibility to autoimmune diabetes J:274578
insulitis J:274578
Tg(IghH280)48Dvs/?
Tg(IgkH280)934Dvs/?

(NOD/ShiLtDvs-Tg(IghH280)48Dvs Tg(IgkH280)934Dvs/Dvs)
increased susceptibility to autoimmune diabetes J:274578
Tg(Ighm-Ctla4Ig/Cd80)1Jbs/0
(involves: FVB/N)
abnormal B cell physiology J:113109
immune system phenotype J:113109
Tg(Ighm-Ctla4Ig/Cd80)1Jbs/0
(NOD.FVB-Tg(Ighm-Ctla4Ig/Cd80)1Jbs)
decreased susceptibility to autoimmune diabetes J:113109
immune system phenotype J:113109
Tg(IghMyc)22Bri/?
(involves: C57BL * C57BL/6 * SJL)
enlarged spleen J:121564
increased lymphocyte cell number J:121564
Tg(IghMyc)22Bri/0
(involves: C57BL/6 * SJL)
abnormal lymphopoiesis J:78177
enlarged lymph nodes J:78177
enlarged spleen J:78177
enlarged thymus J:78177
increased leukocyte cell number J:186117
increased pre-B cell number J:223213
Tg(IghMyc)22Bri/0
(B6.Cg-Tg(IghMyc)22Bri/J)
enlarged lymph nodes J:164200
spleen hyperplasia J:164200
Tg(IghMyc)22Bri/0
(involves: C57BL/6N * SJL)
increased B cell apoptosis J:214383
Tg(IghMyc)22Bri/0
Tg(Igk-V21-Bax)1967Bvn/0

(involves: C57BL/6 * FVB/N)
enlarged spleen J:89049
increased transitional stage B cell number J:89049
Tg(IghMyc)22Bri/0
Xiaptm1Hs/Xiaptm1Hs

(B6.Cg-Xiaptm1Hs Tg(IghMyc)22Bri)
decreased B cell proliferation J:138979
decreased leukocyte cell number J:138979
increased B cell apoptosis J:138979
Tg(IghMyc)186Brn/0
Rpl24Bst/Rpl24+

(involves: C57BL/LiA * C57BLKS * CBA/BrA)
immune system phenotype J:142390
Tg(Igk-Eik-H2-Ead)1Flv/0
Tg(Tcra1H3.1,Tcrb1H3.1)1Vire/0

(involves: C57BL/6 * SJL)
decreased double-positive T cell number J:124574
thymus hypoplasia J:124574
Tg(Igk-Lta/Ltb)4Cys/0
(involves: C57BL/6J * DBA/2J)
abnormal B cell morphology J:73100
Tg(Igk-Lta/Ltb)10Cys/0
(involves: C57BL/6J * DBA/2J)
abnormal B cell morphology J:73100
Tg(Igk-V21-Bax)1967Bvn/0
(involves: FVB/N)
abnormal plasma cell morphology J:89049
increased IgA level J:89049
increased IgE level J:89049
increased IgG1 level J:89049
increased IgG2a level J:89049
increased IgG level J:89049, J:90901
increased IgM level J:89049
increased immunoglobulin level J:89049
increased transitional stage B cell number J:89049
Tg(IGK@yK1)9.2CJkbv/0
(involves: 129P2/OlaHsd)
abnormal B cell morphology J:23827
abnormal immunoglobulin level J:23827
abnormal immunoglobulin light chain V-J recombination J:23827
Tg(IgkH280)934Dvs/?
(NOD/ShiLtDvs-Tg(IgkH280)934Dvs/J)
increased susceptibility to autoimmune diabetes J:274578
insulitis J:274578
Tg(Igkv3-5*-MYC)24Plbe/0
(C57BL/6J-Tg(Igkv3-5*-MYC)DLoxP4Plbe/PlbeMmmh)
abnormal humoral immune response J:131912
abnormal immunoglobulin level J:131912
abnormal plasma cell differentiation J:131912
increased IgG1 level J:131912
increased IgG3 level J:131912
increased plasma cell number J:131912
Tg(Igl-2MOPC315)1275Ust/?
(C57BL/6-Tg(Igl-2MOPC315)1275Ust)
abnormal B cell morphology J:134666
decreased IgM level J:134666
decreased immature B cell number J:134666
Tg(IGL-MYC)3Hm/0
(C57BL/6N-Tg(IGL-MYC)3Hm/Nci)
enlarged lymph nodes J:65245
Tg(Il1rn)1Dih/0
(involves: C57BL/6 * CBA)
decreased circulating interleukin-6 level J:88605
decreased circulating serum amyloid protein level J:61600
decreased inflammatory response J:88605
decreased susceptibility to endotoxin shock J:36387
decreased susceptibility to Herpesvirales infection J:88605
increased susceptibility to bacterial infection J:36387
Tg(Il1rn)1Dih/Tg(Il1rn)1Dih
(involves: C57BL/6 * CBA)
decreased susceptibility to endotoxin shock J:36387
increased circulating interleukin-1 level J:36387
increased susceptibility to bacterial infection J:36387
Tg(IL2-Il10)1Kro/0
(involves: C3H * C57BL/6)
abnormal cytokine secretion J:41588
decreased susceptibility to parasitic infection J:41588
increased susceptibility to bacterial infection J:80569
Tg(IL3,CSF2)C42Pnc/0
(involves: C57BL/6 * CBA)
immune system phenotype J:219403
Tg(ILK3mHEL)3Ccg/0
Tg(TcrHEL3A9)1Mmd/0

(involves: C57BL/6JSfd * C57BL/10Sg * C57BR/cd)
abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal CD4-positive, alpha-beta T cell physiology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
insulitis J:78309
Tg(Ins1-Cat,Tyr)25Pne/0
(NOD.FVB-Tg(Ins1-Cat,Tyr)25Pne)
increased susceptibility to autoimmune diabetes J:108415
Tg(Ins1-Cd80)378Psoh/0
Tg(Ins2-GP)#Psoh/0
Tg(TcrLCMV)327Sdz/0

(involves: C57BL/6 * DBA/2 * FVB/N)
insulitis J:209714
periinsulitis J:209714
Tg(Ins1-EGFP/GH1)14Hara/0
(NOD/ShiLtJ-Tg(Ins1-EGFP/GH1)14Hara)
increased susceptibility to autoimmune diabetes J:127015
Tg(Ins1-EGFP/GH1)14Hara/Tg(Ins1-EGFP/GH1)14Hara
(NOD/ShiLtJ-Tg(Ins1-EGFP/GH1)14Hara)
decreased susceptibility to autoimmune disorder J:127015
insulitis J:127015
Tg(Ins2*Y16A)1Ell/0
(NOD-Tg(Ins2*Y16A)1Ell)
increased susceptibility to autoimmune diabetes J:98583
Tg(Ins2*Y16A)3Ell/0
(NOD-Tg(Ins2*Y16A)3Ell)
increased susceptibility to autoimmune diabetes J:98583
Tg(Ins2-Ccl19)2Cys/0
(involves: C57BL/6 * DBA/2)
abnormal lymph organ development J:77238
Tg(Ins2-Ccl21b)2Cys/0
(involves: C57BL/6 * DBA/2)
abnormal lymph organ development J:77238
Tg(Ins2-CD80)3B7Flv/?
(involves: C57BL/6 * CBA/Ca * NOD/Caj)
increased susceptibility to autoimmune diabetes J:26618
insulitis J:26618
Tg(Ins2-CD80)3B7Flv/0
Tg(Ins2-H2-Ead,Ins2-H2-Eb1b)187-7Bri/0

(involves: C57BL/6 * CBA/Ca * SJL)
increased susceptibility to autoimmune diabetes J:93555
insulitis J:93555
Tg(Ins2-CD80)3B7Flv/0
Tg(Ins2-Tnf)17Flv/0

(involves: C57BL/6 * CBA/Ca)
abnormal cytokine secretion J:93555
increased susceptibility to autoimmune diabetes J:93555
Tg(Ins2-CD86)12B70Flv/0
(involves: C57BL/6 * CBA/Ca)
abnormal cytokine secretion J:93555
decreased susceptibility to autoimmune diabetes J:93555
periinsulitis J:93555
Tg(Ins2-CD86)12B70Flv/0
Tg(Ins2-H2-Ead,Ins2-H2-Eb1b)187-7Bri/0

(involves: C57BL/6 * CBA/Ca * SJL)
abnormal cytokine secretion J:93555
increased susceptibility to autoimmune diabetes J:93555
insulitis J:93555
Tg(Ins2-CD86)12B70Flv/0
Tg(Ins2-Tnf)17Flv/0

(involves: C57BL/6 * CBA/Ca)
abnormal cytokine secretion J:93555
increased susceptibility to autoimmune diabetes J:93555
Tg(Ins2-Cd274)2Mdos/?
(NOD/ShiLt-Tg(Ins2-Cd274)2Mdos)
increased susceptibility to autoimmune diabetes J:118934
Tg(Ins2-cre)5Lt/0
(NOD/ShiLt-Tg(Ins2-cre)5Lt)
increased susceptibility to autoimmune diabetes J:127015
Tg(Ins2-cre)5Lt/Tg(Ins2-cre)5Lt
(NOD/ShiLt-Tg(Ins2-cre)5Lt)
decreased susceptibility to autoimmune disorder J:127015
insulitis J:127015
Tg(Ins2-crmA)27Ngkh/?
(NOD-Tg(Ins2-CrmA)27Ngkh)
increased susceptibility to autoimmune diabetes J:132052
Tg(Ins2-Cxcl13)1Cys/0
(involves: C57BL/6 * DBA/2)
abnormal lymph organ development J:110548
Tg(Ins2-E3)1Dvs/?
(NOD.Cg-Tg(Ins2-E3)1Dvs)
decreased susceptibility to autoimmune diabetes J:68996
Tg(Ins2-E3*309)5Dvs/?
(NOD/ShiLtDvs-Tg(Ins2-E3*309)5Dvs/Dvs)
decreased susceptibility to autoimmune diabetes J:83195
Tg(Ins2-E3*704)2Dvs/?
(NOD/ShiLtDvs-Tg(Ins2-E3*704)2Dvs)
decreased susceptibility to autoimmune diabetes J:83195
Tg(Ins2-E3*734)3Dvs/0
(NOD/ShiLtDvs-Tg(Ins2-E3*734)3Dvs/DvsJ)
decreased susceptibility to autoimmune diabetes J:106340
Tg(Ins2-E3*734)4Dvs/?
(NOD/ShiLtDvs-Tg(Ins2-E3*734)4Dvs/DvsJ)
decreased susceptibility to autoimmune diabetes J:106340
Tg(Ins2-Fas*I246N)1Ach/0
(NOD-Tg(Ins2-Fas*I246N)1Ach)
decreased susceptibility to autoimmune diabetes J:81416
Tg(Ins2-Fas*I246N)1Ach/0
Tg(Ins2-Fasl)24Ach/0

(NOD-Tg(Ins2-Fas*I246N)1Ach Tg(Ins2-Fasl)24Ach)
decreased susceptibility to autoimmune diabetes J:81416
Tg(Ins2-Fasl)24Ach/0
(NOD-Tg(Ins2-Fasl)24Ach/J)
increased susceptibility to autoimmune diabetes J:78679, J:81416
Tg(Ins2-GAD2)1Lt/0
(NOD/ShiLt-Tg(Ins2-GAD2)1Lt)
insulitis J:100251
Tg(Ins2-GAD2)2Lt/0
(NOD/ShiLt-Tg(Ins2-GAD2)2Lt)
abnormal cytokine secretion J:100251
decreased susceptibility to autoimmune diabetes J:100251
insulitis J:100251
Tg(Ins2-GP)34-20Olds/0
(involves: BALB/c * C57BL/6)
abnormal lymphocyte physiology J:81287
abnormal T cell physiology J:81287
increased susceptibility to autoimmune diabetes J:81287
Tg(Ins2-GP)#Psoh/0
(involves: C57BL/6)
insulitis J:81285
Tg(Ins2-GP)#Psoh/0
Tg(TcrLCMV)327Sdz/0

(involves: C57BL/6 * DBA/2)
abnormal B cell selection J:81285
Tg(Ins2-H2-Ead,Ins2-H2-Eb1b)187-7Bri/0
(involves: C57BL/6 * SJL)
decreased susceptibility to autoimmune diabetes J:93555
Tg(Ins2-HA)165Bri/0
(B10.Cg- H2d Tg(Ins2-HA)165Bri/ShrmJ)
abnormal CD4-positive, alpha-beta T cell physiology J:86430
decreased T cell proliferation J:86430
immune system phenotype J:86430
Tg(Ins2-HA)165Bri/0
Tg(TcraCl4,TcrbCl4)1Shrm/0

(involves: BALB/c * C57BL/6 * C57BL/10 * DBA/2)
insulitis J:99756
Tg(Ins2-HA)165Bri/?
Tg(TcraCl4,TcrbCl4)1Shrm/?

(involves: BALB/c * C57BL/6 * C57BL/10)
insulitis J:99756
Tg(Ins2-Iapp)6Soel/Tg(Ins2-Iapp)6Soel
(involves: FVB/N)
decreased susceptibility to autoimmune diabetes J:130022
Tg(Ins2-IAPP)RHFSoel/Tg(Ins2-IAPP)RHFSoel
(involves: FVB/N)
increased susceptibility to autoimmune diabetes J:130022
Tg(Ins2-Lta)#Flv/0
(involves: NOD)
insulitis J:91820
kidney inflammation J:91820
periinsulitis J:91820
Tg(Ins2-Lta)#Flv/0
(involves: C57BL/6)
insulitis J:91820
kidney inflammation J:91820
periinsulitis J:91820
Tg(Ins2-Lta)#Flv/0
(involves: C57BL/6 * CBA)
insulitis J:127705
periinsulitis J:127705
Tg(Ins2-NP)25-3Olds/0
(involves: BALB/c * C57BL/6)
decreased susceptibility to autoimmune diabetes J:81287
increased susceptibility to autoimmune diabetes J:81287
Tg(Ins2-OVA)59Wehi/?
(involves: BALB/c * C57BL/6)
abnormal T cell activation J:99560
increased susceptibility to autoimmune diabetes J:99560
Tg(Ins2-OVA)307Wehi/?
(involves: BALB/c * C57BL/6)
increased susceptibility to autoimmune diabetes J:99560
Tg(Ins2-OVA)307Wehi/0
Tg(TcraTcrb)1100Mjb/0

(involves: C57BL/6 * C57BL/6JWehi)
autoimmune response J:99451
Tg(Ins2-TFRC/OVA)296Wehi/0
(involves: C57BL/6)
abnormal CD8-positive, alpha beta T cell morphology J:98589
abnormal leukocyte migration J:98589
decreased interferon-gamma secretion J:122114
increased susceptibility to autoimmune diabetes J:122114
Tg(Ins2-TFRC/OVA)296Wehi/0
1700016L21RikTg(Itgax-HBEGF/EGFP)57Lan/0

(involves: C57BL/6 * FVB)
decreased T cell proliferation J:122114
Tg(Ins2-TFRC/OVA)296Wehi/0
Tg(TcraTcrb)425Cbn/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:135154
increased double-positive T cell number J:135154
Tg(Ins2-Tnf)17Flv/0
(involves: C57BL/6 * CBA * NOD)
immune system phenotype J:91820
insulitis J:91820
Tg(Ins2-Tnf)17Flv/0
(involves: C57BL/6 * CBA)
insulitis J:91820
Tg(Ins2-Tnf)17Flv/0
(involves: C57BL/6)
decreased CD8-positive, alpha-beta T cell number J:93555
increased CD4-positive, alpha-beta T cell number J:93555
Tg(INS-Il10)#Sar/0
(involves: BALB/c)
pancreas inflammation J:107927
periinsulitis J:107927
Tg(INS-Il10)#Sar/0
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak

(involves: 129S2/SvPas * C57BL/6J * NOD)
increased susceptibility to autoimmune diabetes J:64051
Tg(INS-Il10)#Sar/0
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm

(involves: 129S2/SvPas * C57BL/6J * NOD)
increased susceptibility to autoimmune diabetes J:64051
Tg(INS-MT2A,Tyr)1Pne/0
(FVB-Tg(INS-MT2A,Tyr)1Pne)
abnormal response to transplant J:95089
Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0840Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0869Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA2)1067Fmw/0
Tg(ITGB1)0870Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0840Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0869Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA2)1070Fmw/0
Tg(ITGB1)0870Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0840Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0869Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA2)1075Fmw/0
Tg(ITGB1)0870Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0840Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0869Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0794Fmw/0
Tg(ITGB1)0870Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0840Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0869Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0844Fmw/0
Tg(ITGB1)0870Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0840Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0869Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGA5)0858Fmw/0
Tg(ITGB1)0870Fmw/0

(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGAL-Hhex)2Hro/0
(C3HeB/FeJ-Tg(ITGAL-Hhex)2Hro)
abnormal double-negative T cell morphology J:80777
abnormal thymus corticomedullary boundary morphology J:80777
decreased double-positive T cell number J:80777
decreased leukocyte cell number J:80777
decreased lymphocyte cell number J:80777
decreased T cell number J:80777
increased CD8-positive, alpha-beta T cell number J:80777
thymus hypoplasia J:80777
Tg(ITGAL-Ptprc)FWcr/Tg(ITGAL-Ptprc)FWcr
(involves: BALB/c * C57BL/6)
abnormal T cell differentiation J:158876
Tg(Itgam-FCAR)83Rcmo/0
(involves: C57BL/6 * NOD)
glomerulonephritis J:120534
increased IgA level J:120534
Tg(ITGAM-HBEGF/EGFP)34Lan/0
(involves: FVB/N)
abnormal macrophage morphology J:95141
decreased macrophage cell number J:95141
increased neutrophil cell number J:95141
Tg(ITGAM-HBEGF/EGFP)34Lan/0
(NOD.FVB-Tg(ITGAM-HBEGF/EGFP)34Lan/Jdk)
decreased macrophage cell number J:137009
immune system phenotype J:137009
Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh/0
(C57BL/6-Tg(Itgax-EGFP,-cre,-HBEGF,-luc)2Gjh)
abnormal susceptibility to infection J:194800
immune system phenotype J:194800
increased monocyte cell number J:194800
increased neutrophil cell number J:194800
Tg(Itgax-HBEGF/OVA/EGFP)1Garbi/0
(C57BL/6-Tg(Itgax-HBEGF/OVA/EGFP)1Garbi)
abnormal susceptibility to infection J:194800
decreased dendritic cell number J:194800
increased neutrophil cell number J:194800
Tg(Itgax-TGFBR2)1Flv/0
(C.Cg-Tg(Itgax-TGFBR2)1Flv)
abnormal immune system physiology J:98953
abnormal interferon level J:98953
abnormal NK cell differentiation J:98953
decreased susceptibility to parasitic infection J:98953
immune system phenotype J:98953
increased NK cell number J:98953
Tg(ITGB1)0840Fmw/0
(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGB1)0869Fmw/0
(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(ITGB1)0870Fmw/0
(involves: C57BL/10 * CBA)
dermatitis J:30249
eye inflammation J:30249
Tg(IVL-KLK5)#Hov/0
(involves: C57BL/6 * CBA)
abnormal circulating cytokine level J:210758
abnormal inguinal lymph node morphology J:210758
enlarged lymph nodes J:210758
enlarged spleen J:210758
erythroderma J:210758
increased activated T cell number J:210758
increased IgE level J:210758
lymph node inflammation J:210758
skin inflammation J:210758
Tg(JAK2*V617F)FF1Rsko/0
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
abnormal myelopoiesis J:134364
abnormal spleen morphology J:134364
decreased B cell number J:134364
decreased T cell number J:134364
enlarged spleen J:134364
increased neutrophil cell number J:134364
spleen fibrosis J:134364
Tg(JAK2*V617F)FF1Rsko/0
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal myelopoiesis J:134364
abnormal spleen morphology J:134364
decreased B cell number J:134364
decreased T cell number J:134364
enlarged spleen J:134364
increased neutrophil cell number J:134364
spleen fibrosis J:134364
Tg(JAK2*V617F)FF1Rsko/0
Tg(Tek-cre)1Arnd/0

(involves: C57BL/6 * CBA * DBA/2)
decreased T cell number J:206659
enlarged spleen J:206659
increased neutrophil cell number J:206659
Tg(K18-ACE2)2Prlmn/0
(involves: C57BL/6J * SJL/J)
increased susceptibility to Coronaviridae infection J:283648
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:283648
Tg(K18-ACE2)2Prlmn/0
(B6.Cg-Tg(K18-ACE2)2Prlmn/J)
abnormal chemokine level J:302313
abnormal circulating chemokine level J:294084
abnormal circulating cytokine level J:302313
abnormal cytokine level J:294084, J:302313
abnormal interferon level J:300960, J:302313
abnormal interleukin level J:300960, J:302313
abnormal tumor necrosis factor level J:300960, J:302313
blood vessel inflammation J:300960
brain inflammation J:294084
bronchiolitis J:302313
conjunctivitis J:294084
cytokine storm J:300960
enhanced humoral immune response J:302313
increased circulating CXCL10 level J:302313
increased circulating interferon-gamma level J:302313
increased circulating interleukin-6 level J:294084
increased circulating interleukin-10 level J:294084, J:302313
increased circulating tumor necrosis factor level J:294084
increased CXCL10 level J:300960
increased IgG level J:302313
increased IgM level J:302313
increased leukocyte cell number J:294084
increased lymphocyte cell number J:302313
increased macrophage cell number J:294084, J:302313
increased neutrophil cell number J:294084, J:300960, J:302313
increased susceptibility to Coronaviridae infection J:294084, J:300960, J:302313, J:296067
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:294084, J:300960
increased susceptibility to Orthomyxoviridae infection J:296067
increased susceptibility to viral infection J:296067
increased susceptibility to viral infection induced morbidity/mortality J:296067
increased T cell number J:300960
interstitial pneumonia J:300960, J:302313
liver inflammation J:300960
lung inflammation J:294084, J:302313
meningitis J:294084, J:302313
meningoencephalitis J:300960, J:296067
microgliosis J:294084
rhinitis J:300960
Tg(Kit*D814V)1Roer/0
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal mast cell morphology J:169611
colitis J:169611
enlarged spleen J:169611
increased mast cell number J:169611
large intestinal inflammation J:169611
small intestinal inflammation J:169611
Tg(Kit*D814V)2Roer/0
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal mast cell morphology J:169611
colitis J:169611
increased mast cell number J:169611
large intestinal inflammation J:169611
small intestinal inflammation J:169611
Tg(Kit*D814V)3Roer/0
Tg(Mx1-cre)1Cgn/0

(involves: C57BL/6 * CBA)
abnormal mast cell morphology J:169611
colitis J:169611
enlarged spleen J:169611
increased mast cell number J:169611
large intestinal inflammation J:169611
Tg(KLK4mHEL)6Ccg/0
Tg(TcrHEL3A9)1Mmd/0

(involves: C57BL/6 * C57BL/10 * C57BR/cd)
decreased CD4-positive, alpha-beta T cell number J:78309
decreased double-positive T cell number J:78309
Tg(KRT5-IKBKB)1Armz/0
(involves: C57BL/6 * DBA/2)
increased interleukin-1 alpha secretion J:160072
increased interleukin-6 secretion J:160072
increased tumor necrosis factor secretion J:160072
Tg(KRT5-IKBKB)2Armz/0
(involves: C57BL/6 * DBA/2)
abnormal cytokine level J:160072
abnormal immune serum protein physiology J:160072
abnormal melanophage morphology J:160072
dermatitis J:160072
increased circulating interferon-gamma level J:160072
increased circulating interleukin-1 alpha level J:160072
increased circulating interleukin-2 level J:160072
increased circulating interleukin-4 level J:160072
increased circulating interleukin-5 level J:160072
increased circulating interleukin-6 level J:160072
increased circulating interleukin-10 level J:160072
increased circulating tumor necrosis factor level J:160072
increased interleukin-1 alpha secretion J:160072
increased interleukin-6 secretion J:160072
increased tumor necrosis factor secretion J:160072
Tg(KRT5-Nfkbia*)3Rto/0
Tg(Krt5-Tnfr1)#Rsab/0
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak

(involves: 129S2/SvPas * C57BL/6 * CBA)
skin inflammation J:208995
Tg(KRT5-rtTA)1Glk/0
Tg(tetO-Tfrc/EGFP/Ova)#Sfz/0

(involves: FVB/N)
immune system phenotype J:199558
Tg(KRT5-rtTA)1Glk/0
Tg(tetO-Tfrc/EGFP/Ova)#Sfz/0
Tg(tetO/CMV-Tslp)#Sfz/0

(involves: C3H * C57BL/6 * FVB/N)
increased T cell proliferation J:199558
respiratory system inflammation J:199558
skin inflammation J:199558
Tg(KRT5-rtTA)1Glk/0
Tg(tetO-TGFB1*C223S*C225S)1Glk/0

(involves: FVB/N)
dermatitis J:70670
skin inflammation J:70670
Tg(KRT5-rtTA)1Glk/0
Tg(tetO/CMV-Tslp)#Sfz/0

(involves: C3H * C57BL/6 * FVB/N)
abnormal cytokine level J:100506
abnormal lymph node morphology J:100506
conjunctivitis J:100506
decreased IgG2a level J:100506
dermatitis J:100506
enlarged lymph nodes J:100506
enlarged spleen J:100506
increased CD4-positive, alpha-beta T cell number J:100506
increased IgE level J:100506
increased IgG1 level J:100506
Tg(KRT5-rtTA)1Glk/0
Tg(tetO/CMV-Tslp)#Sfz/0

(C.Cg-Tg(KRT5-rtTA)1Glk Tg(tetO/CMV-Tslp)#Sfz)
abnormal B cell activation J:182756
increased autoantibody level J:182756
increased B cell proliferation J:182756
increased circulating interleukin-4 level J:182756
increased susceptibility to autoimmune hemolytic anemia J:182756
Tg(KRT5-rtTA)#Glk/0
Tg(tetO-cre)1Jaw/0
Wlstm1.1Lan/Wlstm1.1Lan

(involves: 129S6/SvEvTac * C57BL/6 * FVB/N)
cutaneous mastocytosis J:204142
Tg(KRT5-rtTA)#Glk/0
Tg(tetO-S100a7a)#Yus/0

(involves: FVB/N)
abnormal chemokine secretion J:168000
increased interleukin-1 alpha secretion J:168000
increased tumor necrosis factor secretion J:168000
Tg(KRT5-TGFB1)F2020Xjw/0
(involves: C57BL/6 * DBA/2 * ICR)
abnormal Langerhans cell morphology J:90118
abnormal Langerhans cell physiology J:90118
cutaneous mastocytosis J:90118
decreased Langerhans cell number J:90118
skin inflammation J:90118
Tg(KRT5-tTA)1216Glk/0
Tg(tetO-Il13)1Tazh/0

(B6.Cg-Tg(KRT5-tTA)1216Glk Tg(tetO-Il13)1Tazh)
cutaneous mastocytosis J:150232
dermatitis J:150232
increased IgE level J:150232
increased IgG1 level J:150232
increased interleukin-4 secretion J:150232
increased interleukin-13 secretion J:150232
Tg(KRT5-tTA)1216Glk/0
Tg(tetO-LMNA*G608G,-EGFP)VF1-07Maer/0

(involves: FVB/N)
periodontium inflammation J:145312
skin inflammation J:145312
Tg(KRT5-tTA)1216Glk/0
Tg(tetO-Tek)1Dmt/0

(involves: CD-1 * FVB/N)
abnormal interleukin secretion J:147438
increased interferon-gamma secretion J:147438
increased interleukin-12 secretion J:147438
increased interleukin-17 secretion J:147438
increased interleukin-23 secretion J:147438
skin inflammation J:147438
Tg(KRT5-tTA)1216Glk/0
Tg(tetO-TGFB1*C223S*C225S)1Glk/0

(involves: FVB/N)
dermatitis J:70670
skin inflammation J:70670
Tg(Krt14-Angptl2)1Yo/0
(C.Cg-Tg(Krt14-Angptl2)1Yo)
skin inflammation J:152387, J:181261
Tg(KRT14-CASP1)1Miz/0
(involves: C57BL/6)
abnormal T cell physiology J:78602
decreased T cell number J:78602
dermatitis J:78602, J:79706
increased circulating interleukin-18 level J:78602, J:79706
increased IgE level J:78602
increased IgG1 level J:78602
increased neutrophil cell number J:78602
increased susceptibility to bacterial infection J:79706
increased susceptibility to bacterial infection induced morbidity/mortality J:79706
Tg(KRT14-cre)1Amc/0
Trpv3tm1.1Clph/Trpv3tm1.1Clph

(involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA * Swiss Webster)
erythroderma J:164741
Tg(KRT14-FIGF)2Ali/0
(involves: FVB/N)
lymphatic vessel hyperplasia J:137909, J:68138
Tg(KRT14-FLT4/IGHG1)#Ali/0
(either: (involves: FVB/N) or (involves: BALB/c * DBA))
abnormal lymphatic vessel morphology J:201429
abnormal mononuclear phagocyte morphology J:201429
Tg(Krt14-Ifnk)#Cya/0
(C57BL/6N-Tg(Krt14-Ifnk)#Cya)
enlarged spleen J:322130
increased susceptibility to chemically induced skin inflammation J:322130
Tg(KRT14-Il1f6)1Hblu/?
(involves: C57BL/6 * DBA/2)
abnormal chemokine level J:126327
skin inflammation J:126327
Tg(KRT14-Il4)#Lsch/0
(involves: BALB/cBy * C57BL/6)
blepharitis J:126285
conjunctivitis J:126285
decreased IgG2a level J:126285
dermatitis J:126285
increased IgE level J:126285
increased IgG1 level J:126285
increased mast cell degranulation J:126285
increased susceptibility to bacterial infection J:126285
skin inflammation J:126285
Tg(KRT14-Il7)1Tsk/0
(FVB/N-Tg(KRT14-Il7)1Tsk)
blepharitis J:42565
skin inflammation J:42565
Tg(KRT14-Il7)1Tsk/Tg(KRT14-Il7)1Tsk
(FVB/N-Tg(KRT14-Il7)1Tsk)
skin inflammation J:42565
Tg(KRT14-Il18)#Knak/0
(C57BL/6-Tg(KRT14-Il18)#Knak)
abnormal T cell physiology J:78602
decreased T cell number J:78602
dermatitis J:78602
increased circulating interleukin-18 level J:78602
increased IgE level J:78602
increased IgG1 level J:78602
increased neutrophil cell number J:78602
Tg(Krt14-Rac1*G12V)#Mrnk/0
(involves: CBA/CaJ)
abnormal circulating interleukin level J:237134
joint inflammation J:237134
skin inflammation J:237134
Tg(KRT14-Tslp)1Pcn/0
(involves: C57BL/6 * SJL)
abnormal lymphocyte physiology J:102470
enlarged spleen J:102470
increased immunoglobulin level J:102470
lymph node hyperplasia J:102470
Tg(KRT14-Vegfa)3Dtm/0
(FVB/N-Tg(KRT14-Vegfa)3Dtm)
abnormal leukocyte adhesion J:104245
abnormal lymphatic vessel morphology J:111924
enhanced leukocyte tethering or rolling J:104245
enlarged lymph nodes J:92643
enlarged lymphatic vessel J:92643
increased macrophage cell number J:111924
increased mast cell number J:104245
Tg(KRT14-VEGFC*)1Ali/0
(involves: FVB/N)
lymphatic vessel hyperplasia J:68138
Tg(KRT14-Vegfd)1Ali/0
Vegfctm1Ali/Vegfc+

(involves: 129S1/Sv * 129X1/SvJ * FVB)
abnormal lymphatic vessel morphology J:137909
Tg(KRT14-VP16/NR1I2)13Sdub/?
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell number J:258435
abnormal CD8-positive, alpha beta T cell morphology J:258435
abnormal dendritic cell migration J:258435
abnormal innate immunity J:258435
decreased interleukin-1 beta secretion J:258435
dermatitis J:258435
enhanced humoral immune response J:258435
enlarged lymph nodes J:258435
increased dendritic cell number J:258435
increased effector memory T-helper cell number J:258435
increased gamma-delta T cell number J:258435
increased IgE level J:258435
increased IgG1 level J:258435
increased leukocyte cell number J:258435
skin inflammation J:258435
Tg(KRT18*R89C)22Rgo/0
(involves: FVB/N)
chronic liver inflammation J:241700
Tg(KRT18*R89C)30Rgo/0
(involves: FVB/N)
chronic liver inflammation J:241700
Tg(KRT18*R89C)50Rgo/0
(involves: FVB/N)
chronic liver inflammation J:241700
Tg(KRT18-DPP4)3Pbmj/0
(involves: C57BL/6J * SJL/J)
abnormal cytokine secretion J:285467
abnormal mononuclear cell morphology J:286231
brain inflammation J:285467
increased lymphocyte cell number J:286231
increased susceptibility to Coronaviridae infection J:286231, J:285467
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:286231, J:285467
interstitial pneumonia J:286231
lung inflammation J:286231, J:285467
Tg(LANA,vFLIP,vCYC)801Dtmr/?
(involves: C57BL/6)
abnormal B cell activation J:196403
abnormal B cell differentiation J:196403
abnormal germinal center B cell physiology J:196403
abnormal marginal zone B cell morphology J:196403
abnormal marginal zone B cell physiology J:196403
abnormal spleen morphology J:196403
enlarged spleen J:196403
increased B cell proliferation J:196403
increased germinal center B cell number J:196403
increased IgG1 level J:196403
increased IgG3 level J:196403
increased marginal zone B cell number J:196403
increased mature B cell number J:196403
increased plasma cell number J:196403
Tg(Lck-Akt1*)M-1Pnt/0
(involves: C3H/He * C57BL/6)
decreased thymocyte number J:73487
enlarged spleen J:73487
increased double-negative T cell number J:135903
increased single-positive T cell number J:135903
Tg(Lck-Akt1*E40K)E-3Pnt/0
(involves: C3H/He * C57BL/6)
decreased thymocyte number J:73487
enlarged spleen J:73487
Tg(Lck-Akt1*E40K)E-3Pnt/0
(Not Specified)
abnormal T cell differentiation J:144975
Tg(Lck-Bcl2l1)1Cant/?
(B6.Cg-Tg(Lck-Bcl2l1)1Cant)
increased interleukin-2 secretion J:77507
increased memory T cell number J:77507
increased T cell proliferation J:77507
Tg(Lck-cre)1Cwi/0
(involves: C57BL/6 * DBA/2)
decreased thymocyte number J:226234
Tg(Lck-cre)548Jxm/?
Tgfb1tm2.1Doe/Tgfb1tm2.1Doe

(involves: 129S6/SvEvTac * Black Swiss * C57BL/6 * CBA)
abnormal immune system organ morphology J:150024
abnormal T cell activation J:150024
abnormal T cell subpopulation ratio J:150024
decreased spleen weight J:150024
decreased thymus weight J:150024
increased inflammatory response J:150024
increased interferon-gamma secretion J:150024
increased interleukin-2 secretion J:150024
lung inflammation J:150024
salivary gland inflammation J:150024
spleen hypoplasia J:150024
thymus hypoplasia J:150024
Tg(Lck-cre)548Jxm/?
Upf2tm1Btp/Upf2tm1Btp

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal T cell receptor beta chain V(D)J recombination J:134765
decreased CD4-positive, alpha-beta T cell number J:134765
decreased CD8-positive, alpha-beta T cell number J:134765
decreased double-positive T cell number J:134765
thymus hypoplasia J:134765
Tg(Lck-cre)I57Jxm/?
Traf2tm1Rbr/Traf2tm1Rbr

(involves: C57BL/6 * ICR)
absent follicular B cells J:132877
absent marginal zone B cells J:132877
decreased mature B cell number J:132877
Tg(Lck-cre)I57Jxm/?
Traf3tm1Rbr/Traf3tm1Rbr

(involves: C57BL/6 * ICR * SJL)
abnormal T cell physiology J:132877
decreased CD4-positive, alpha-beta T cell number J:132877
decreased CD8-positive, alpha-beta T cell number J:132877
Tg(Lck-CrmA)1Hed/0
(involves: BALB/c * C57BL/6J)
decreased T cell apoptosis J:100451
immune system phenotype J:100451
Tg(Lck-CrmA)1Hed/?
(involves: BALB/c * C57BL/6J)
decreased thymocyte apoptosis J:100451
Tg(Lck-CrmA)1Hed/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(BALB/c * C57BL/6)
immune system phenotype J:100451
Tg(Lck-CrmA)1Hed/Tg(Lck-CrmA)1Hed
(involves: BALB/c * C57BL/6J)
immune system phenotype J:100451
Tg(Lck-Cxadr)1Jdgr/0
(FVB-Tg(Lck-Cxadr)1Jdgr)
abnormal T cell physiology J:109884
decreased T cell apoptosis J:109884
decreased T cell proliferation J:109884
Tg(Lck-FADD)1Hed/0
(involves: BALB/c * C57BL/6)
abnormal T cell proliferation J:100451
arrested T cell differentiation J:100451
decreased T cell number J:100451
decreased thymocyte number J:100451
Tg(Lck-FADD)1Hed/?
(involves: BALB/c * C57BL/6)
abnormal T cell physiology J:100451
decreased thymocyte apoptosis J:100451
immune system phenotype J:100451
Tg(Lck-FADD)1Hed/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: BALB/c * C57BL/6J * C57L/J * DBA/2J)
immune system phenotype J:100451
Tg(Lck-FADD)1Hed/Tg(Lck-FADD)1Hed
(involves: BALB/c * C57BL/6)
abnormal T cell differentiation J:100451
decreased T cell number J:100451
decreased thymocyte number J:100451
immune system phenotype J:100451
Tg(Lck-Hhex)1Hro/0
(C3HeB/FeJ-Tg(Lck-Hhex)1Hro)
abnormal double-negative T cell morphology J:80777
decreased double-positive T cell number J:80777
decreased leukocyte cell number J:80777
decreased lymphocyte cell number J:80777
decreased T cell number J:80777
increased CD8-positive, alpha-beta T cell number J:80777
thymus hyperplasia J:80777
Tg(Lck-Il31)1Jagr/0
(involves: C3H * C57BL/6)
abnormal immune system physiology J:91124
abnormal leukopoiesis J:91124
conjunctivitis J:91124
cutaneous mastocytosis J:91124
decreased T cell number J:91124
dermatitis J:91124
enlarged lymph nodes J:91124
increased activated T cell number J:91124
increased B cell number J:91124
increased memory T cell number J:91124
Tg(Lck-LMO1)11Sjk/0
Tg(STIL-TAL1)A5(3)Alpa/0

(involves: C3H * C3H/HeRos * C57BL/6 * C57BL/10Ros)
abnormal inflammatory response J:40868
enlarged lymph nodes J:40868
enlarged spleen J:40868
enlarged thymus J:40868
increased leukocyte cell number J:40868
Tg(LCK-NFKBIA)5Dwb/0
(involves: C57BL/6 * DBA/2)
abnormal CD8-positive, alpha-beta T cell differentiation J:93003
decreased CD4-positive, alpha-beta T cell number J:93003
decreased CD8-positive, alpha-beta T cell number J:93003
decreased interleukin-2 secretion J:93003
decreased T cell proliferation J:93003
increased T cell apoptosis J:93003
Tg(LCK-NFKBIA)5Dwb/?
(involves: BALB/c * C57BL/6 * DBA/2)
abnormal T-helper 1 physiology J:145531
decreased interferon-gamma secretion J:145531
decreased susceptibility to type I hypersensitivity reaction J:145531
decreased susceptibility to type IV hypersensitivity reaction J:145531
Tg(LCK-NFKBIA)5Dwb/?
Tg(Tcra,Tcrb)1Mcd/?

(involves: BALB/c * C57BL/6 * DBA/2)
decreased interferon-gamma secretion J:145531
Tg(Lck-Notch3)#Issc/0
(involves: C57BL/6 * DBA/2)
abnormal T cell differentiation J:63300
enlarged lymph nodes J:63300
enlarged spleen J:63300
increased double-negative T cell number J:63300
increased thymocyte number J:63300
thymus hyperplasia J:63300
Tg(Lck-Socs3)1Kubo/0
(Not Specified)
abnormal CD4-positive T cell differentiation J:132905
decreased interleukin-2 secretion J:128797
decreased susceptibility to experimental autoimmune encephalomyelitis J:132905
decreased T cell number J:128797
decreased T cell proliferation J:128797
decreased thymocyte number J:128797
Tg(Lck-Sox13)#Jskg/0
(involves: C57BL/6)
decreased double-positive T cell number J:117301
decreased T cell proliferation J:117301
decreased thymocyte number J:117301
increased thymocyte apoptosis J:117301
Tg(Lck-Stat5b*)1Mafa/0
(Not Specified)
decreased mature B cell number J:132669
increased B cell proliferation J:132669
Tg(Lck-Stk17b)26.1Wals/?
(B6.Cg-Tg(Lck-Stk17b)26.1Wals)
decreased CD4-positive, alpha-beta T cell number J:149973
decreased CD8-positive, alpha-beta T cell number J:149973
decreased single-positive T cell number J:149973
decreased thymocyte number J:149973
enlarged spleen J:149973
increased anti-nuclear antigen antibody level J:149973
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:149973
increased double-positive T cell number J:149973
increased interleukin-2 secretion J:149973
increased spleen weight J:149973
increased susceptibility to experimental autoimmune encephalomyelitis J:149973
increased T cell proliferation J:149973
spleen hyperplasia J:149973
Tg(Lck-Stk17b)26.1Wals/?
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: C57BL/6 * C57BL/10)
abnormal T cell differentiation J:149973
decreased CD8-positive, alpha-beta T cell number J:149973
decreased thymocyte number J:149973
increased CD8-positive, alpha-beta T cell number J:149973
Tg(Lck-Tal1)4709Led/0
(FVB/N-Tg(Lck-Tal1)4709Led)
abnormal thymus morphology J:36076
enlarged spleen J:36076
Tg(Lck-Tax)53Hall/0
(involves: C57BL/6)
enlarged lymph nodes J:129531
enlarged spleen J:129531
hepatosplenomegaly J:129531
increased susceptibility to fungal infection J:129531
Tg(Lck-Tnfsf4)1Nish/0
(B6.Cg-Tg(Lck-Tnfsf4)1Nish)
abnormal CD4-positive, alpha-beta T cell physiology J:194882
abnormal cytokine secretion J:80214
abnormal T cell subpopulation ratio J:194882
increased CD4-positive, alpha-beta T cell number J:194882
increased interleukin-13 secretion J:194882
increased regulatory T cell number J:194882
increased susceptibility to type IV hypersensitivity reaction J:80214
increased T cell proliferation J:80214
lung inflammation J:194882
Tg(Lck-Tnfsf4)1Nish/0
(C.Cg-Tg(Lck-Tnfsf4)1Nish)
abnormal CD4-positive, alpha-beta T cell physiology J:194882
increased CD4-positive, alpha-beta T cell number J:194882
increased interleukin-13 secretion J:194882
increased regulatory T cell number J:194882
Tg(Lck-TNFSF13)3919Mhah/0
(B6.Cg-Tg(Lck-TNFSF13)3919Mhah)
abnormal immune system organ morphology J:94628
abnormal mesenteric lymph node morphology J:94628
abnormal spleen morphology J:94628
decreased B cell apoptosis J:94628
enlarged mesenteric lymph nodes J:94628
enlarged Peyer's patches J:94628
increased B cell number J:94628
increased B-1 B cell number J:94628
increased CD4-positive, alpha-beta T cell number J:94628
increased CD8-positive, alpha-beta T cell number J:94628
increased IgA level J:94628
intermingled spleen red and white pulp J:94628
spleen hyperplasia J:94628
Tg(Lck-Tnfsf14)24Yxf/?
(C57BL/6-Tg(Lck-Tnfsf14)24Yxf)
abnormal complement protein level J:128976
abnormal inflammatory response J:128976
abnormal lymph node cell ratio J:129951
abnormal T cell physiology J:120962, J:129951
colitis J:129951
glomerulonephritis J:129951
increased anti-double stranded DNA antibody level J:129951
increased anti-nuclear antigen antibody level J:128976
increased autoantibody level J:129951
increased IgA level J:128976
increased IgG level J:128976
increased spleen weight J:129951
increased T cell proliferation J:129951
intestinal inflammation J:128976
liver inflammation J:129951
lung inflammation J:129951
lymph node hyperplasia J:129951
myositis J:129951
small intestinal inflammation J:120962
spleen hyperplasia J:129951
Tg(Lck-Tnfsf15,-EGFP)#Targ/0
(involves: C57BL/6)
increased CD4-positive, alpha-beta memory T cell number J:169462
increased CD8-positive, alpha-beta memory T cell number J:169462
increased interferon-gamma secretion J:169462
increased interleukin-17 secretion J:169462
small intestinal inflammation J:169462
Tg(Lck-Tslp)1Chea/0
(B6.Cg-Tg(Lck-Tslp)1Chea)
enlarged lymph nodes J:72982
enlarged spleen J:72982
glomerulonephritis J:72982
increased anti-nuclear antigen antibody level J:72982
increased immunoglobulin level J:72982
increased spleen weight J:72982
liver inflammation J:72982
lung inflammation J:72982
Tg(Lck-VIPR2)1Ejg/0
(C57BL/6-Tg(Lck-VIPR2)1Ejg)
decreased interferon-gamma secretion J:127974
decreased susceptibility to type IV hypersensitivity reaction J:127974
increased eosinophil cell number J:127974
increased IgE level J:127974
increased IgG1 level J:127974
increased interleukin-4 secretion J:127974
increased interleukin-5 secretion J:127974
increased susceptibility to type I hypersensitivity reaction J:127974
Tg(Lck/Emu-Rftn1)1Ayos/?
(involves: C57BL/6)
increased IgG1 level J:150299
increased IgG2a level J:150299
increased IgG3 level J:150299
increased IgM level J:150299
increased interferon-gamma secretion J:150299
increased interleukin-4 secretion J:150299
increased interleukin-17 secretion J:150299
increased susceptibility to experimental autoimmune encephalomyelitis J:150299
increased T cell proliferation J:150299
Tg(LckIl4)1315Dbl/0
(involves: C57BL/6J * DBA/2J)
abnormal osteoclast physiology J:107359
abnormal T cell activation J:92453
abnormal T cell differentiation J:92453
abnormal T cell number J:92453
abnormal thymocyte activation J:92453
abnormal thymus cell ratio J:92453
abnormal thymus morphology J:92453
absent CD8-positive, alpha-beta T cells J:92453
decreased CD4-positive, alpha-beta T cell number J:92453
decreased double-positive T cell number J:92453
increased CD4-positive, alpha-beta T cell number J:92453
increased CD8-positive, alpha-beta T cell number J:92453
increased double-negative T cell number J:92453
increased IgG2a level J:92453
increased interleukin-4 secretion J:92453
increased susceptibility to parasitic infection J:92453
thymus cortex hypoplasia J:92453
thymus hypoplasia J:92453
Tg(LckNotch1)9Erob/?
(involves: C57BL/6 * CBA/J)
abnormal CD8-positive, alpha-beta T cell differentiation J:93005
abnormal thymus cell ratio J:93005
decreased CD4-positive, alpha-beta T cell number J:93005
increased CD8-positive, alpha-beta T cell number J:93005
Tg(LCKprBCL2)36Sjk/?
(involves: C3H * C57BL/6)
abnormal T cell number J:28635
abnormal T cell subpopulation ratio J:11548
abnormal thymus cell ratio J:11548
decreased T cell apoptosis J:11548
increased CD8-positive, alpha-beta T cell number J:11548
increased T cell number J:11548
Tg(LCKprBCL2)36Sjk/0
(B6.Cg-Tg(LCKprBCL2)36Sjk)
abnormal CD4-positive, alpha-beta T cell number J:217939
abnormal T cell subpopulation ratio J:217939
increased regulatory T cell number J:217939
Tg(LCKprBCL2)36Sjk/0
(involves: C57BL/6 * CBA/J)
abnormal T cell clonal deletion J:217939
decreased thymocyte apoptosis J:217939
Tg(LCKprBCL2)36Sjk/0
Tg(Nr4a1-EGFP/cre)820Khog/0

(involves: C57BL/6 * C57BL/6J)
abnormal T cell clonal deletion J:217939
decreased thymocyte apoptosis J:217939
Tg(LCKprBCL2)36Sjk/0
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: C57BL/6 * C57BL/6J * DBA/2J)
abnormal T cell clonal deletion J:217939
decreased thymocyte apoptosis J:217939
Tg(LCR-HBA2,LCR-HBB*)1Cos/0
(involves: C57BL/6J * CBA/J)
enlarged spleen J:94193
Tg(Ly6a-BCR/ABL1)IS1AIsg/0
(involves: C57BL/6J * CBA)
abnormal lymph node morphology J:144382
abnormal spleen morphology J:144382
increased leukocyte cell number J:144382
increased neutrophil cell number J:144382
increased spleen red pulp amount J:144382
increased spleen weight J:144382
Tg(Ly6a-BCR/ABL1)IS1BIsg/0
(involves: C57BL/6J * CBA)
abnormal lymph node morphology J:144382
abnormal spleen morphology J:144382
increased leukocyte cell number J:144382
increased neutrophil cell number J:144382
increased spleen red pulp amount J:144382
increased spleen weight J:144382
Tg(Ly6a-GCSAM)102AIsg/0
(involves: C57BL/6J * CBA)
abnormal spleen morphology J:221238
decreased B-1 B cell number J:221238
enlarged Peyer's patches J:221238
enlarged spleen J:221238
increased B cell proliferation J:221238
increased B-1 B cell number J:221238
increased IgG level J:221238
increased inflammatory response J:221238
increased spleen white pulp amount J:221238
lymphoid hyperplasia J:221238
Tg(Ly6a-SET/NUP214)2969Gcg/0
(involves: FVB/NJ)
abnormal B cell differentiation J:142938
decreased leukocyte cell number J:142938
decreased lymphocyte cell number J:142938
decreased pre-B cell number J:142938
decreased pro-B cell number J:142938
increased B cell apoptosis J:142938
Tg(Ly6a-TK,-BCR/ABL1)IS9AIsg/0
(involves: C57BL/6J * CBA)
increased leukocyte cell number J:144382
increased neutrophil cell number J:144382
Tg(Ly6e-MALT1)#Isg/0
(involves: C57BL/6 * CBA)
increased mature B cell number J:185590
increased pre-B cell number J:185590
increased pro-B cell number J:185590
Tg(LYZ-rtTA2S*M2,tetO-ELAVL1)632Dkon/0
(B6.Cg-Tg(LYZ-rtTA2S*M2,tetO-ELAVL1)632Dkon)
decreased susceptibility to induced colitis J:184388
Tg(Mbp-Pad2)28Fgm/0
(involves: CD-1)
abnormal tumor necrosis factor level J:142650
Tg(Mbp-SNCA)1Ema/0
(involves: C57BL/6 * DBA/2)
brain inflammation J:207162
Tg(MCL1)8Caig/0
(involves: C57BL/6 * SJL)
abnormal immature B cell morphology J:50604
abnormal leukocyte physiology J:50604
abnormal macrophage apoptosis J:95913
abnormal mast cell differentiation J:50604
abnormal monocyte differentiation J:50604
decreased B cell apoptosis J:50604
decreased splenocyte apoptosis J:50604
decreased T cell apoptosis J:50604
increased spleen white pulp amount J:50604
increased susceptibility to bacterial infection J:95913
increased thymocyte number J:50604
spleen hyperplasia J:50604
Tg(Mcpt8-cre)1Voeh/0
(involves: C57BL/6)
decreased basophil cell number J:164432
decreased inflammatory response J:164432
immune system phenotype J:164432
Tg(Mir125a)#Smoc/0
(involves: C57BL/6)
decreased interferon-gamma secretion J:224880
decreased susceptibility to experimental autoimmune encephalomyelitis J:224880
Tg(ML5sHEL)5Ccg/0
(C57BL/6-Tg(ML5sHEL)5Ccg)
abnormal B cell anergy J:78308
Tg(ML5sHEL)5Ccg/0
(involves: C57BL/6JSfd * CBA)
abnormal B cell anergy J:78308
abnormal T cell anergy J:78308
Tg(ML5sHEL)5Ccg/0
Tg(TcrHEL3A9)1Mmd/0

(involves: C57BL/6 * C57BL/10 * C57BR/cd)
abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal CD4-positive, alpha-beta T cell physiology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
decreased double-positive T cell number J:78309
Tg(ML5sHEL)5Ccg/0
Tg(TcrHEL3A9)1Mmd/0
Tg(TLK2mHEL)2Ccg/0

(involves: C57BL/6JSfd * C57BL/10 * C57BR/cd)
abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal CD4-positive, alpha-beta T cell physiology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
decreased double-positive T cell number J:78309
thyroid gland inflammation J:78309
Tg(MMTV-ENPP2)#Gbm/0
(FVB/N-Tg(MMTV-ENPP2)#Gbm)
mastitis J:149661
Tg(MMTV-Erbb2)9Pjo/0
(involves: BALB/c * C3H * C57BL/6)
enlarged spleen J:72129
increased spleen red pulp amount J:72129
Tg(MMTV-Erbb2)10Pjo/0
(involves: BALB/c * C3H * C57BL/6)
enlarged spleen J:72129
increased spleen red pulp amount J:72129
Tg(MMTV-Erbb2)12Pjo/0
(involves: BALB/c * C3H * C57BL/6)
enlarged spleen J:72129
increased spleen red pulp amount J:72129
Tg(MMTV-Erbb2)17Pjo/0
(involves: BALB/c * C3H * C57BL/6)
enlarged spleen J:72129
increased spleen red pulp amount J:72129
Tg(MMTV-LPAR1)2Gbm/Tg(MMTV-LPAR1)2Gbm
(FVB/N-Tg(MMTV-LPAR1)2Gbm)
mastitis J:149661
Tg(MMTV-LPAR1)7Gbm/Tg(MMTV-LPAR1)7Gbm
(FVB/N-Tg(MMTV-LPAR1)7Gbm)
mastitis J:149661
Tg(MMTV-LPAR1)#Gbm/Tg(MMTV-LPAR1)#Gbm
(FVB/N-Tg(MMTV-LPAR1)#Gbm)
mastitis J:149661
Tg(MMTV-LPAR2)3Gbm/Tg(MMTV-LPAR2)3Gbm
(FVB/N-Tg(MMTV-LPAR2)3Gbm)
mastitis J:149661
Tg(MMTV-LPAR2)6Gbm/Tg(MMTV-LPAR2)6Gbm
(FVB/N-Tg(MMTV-LPAR2)6Gbm)
mastitis J:149661
Tg(MMTV-LPAR2)#Gbm/Tg(MMTV-LPAR2)#Gbm
(FVB/N-Tg(MMTV-LPAR2)#Gbm)
mastitis J:149661
Tg(MMTV-LPAR3)3Gbm/Tg(MMTV-LPAR3)3Gbm
(FVB/N-Tg(MMTV-LPAR3)3Gbm)
mastitis J:149661
Tg(MMTV-LPAR3)#Gbm/Tg(MMTV-LPAR3)#Gbm
(FVB/N-Tg(MMTV-LPAR3)#Gbm)
mastitis J:149661
Tg(MMTV-PyVT)#Mul/0
(B6.FVB-Tg(MMTV-PyVT)#Mul)
abnormal circulating cytokine level J:147923
abnormal lymph node cell ratio J:147923
abnormal lymph node morphology J:147923
abnormal splenic cell ratio J:147923
abnormal T cell physiology J:147923
decreased B cell proliferation J:147923
decreased splenocyte proliferation J:147923
decreased T cell proliferation J:147923
enlarged spleen J:147923
increased circulating tumor necrosis factor level J:147923
increased regulatory T cell number J:147923
increased splenocyte number J:147923
Tg(MMTV-Scgb1a1)#Abm/0
(involves: C57BL/6 * SJL)
increased IgA level J:57504
Tg(Mpz-RAF1/ESR1)A668Ayld/0
(involves: C57BL/6J * CBA/J)
increased inflammatory response J:182703
increased macrophage cell number J:182703
increased mast cell number J:182703
increased neutrophil cell number J:182703
increased T cell number J:182703
Tg(Msmb-TAg)183-2Xuan/0
(involves: C57BL/6 * CBA)
enlarged lymph nodes J:80313
Tg(Msr1-MMP9)#Apar/0
(B6.Cg-Tg(Msr1-MMP9)#Apar)
abnormal macrophage physiology J:136830
decreased inflammatory response J:129959
immune system phenotype J:136830
Tg(MSR1-Plau)1Ddi/0
(involves: C57BL/6 * SJL)
heart inflammation J:101486
Tg(Mt1-Crry)26Quig/?
(involves: CD-1)
abnormal inflammatory response J:117777
Tg(Mt1-IL6)28Gci/0
(involves: C57BL/6 * DBA/2)
abnormal spleen morphology J:18424
enlarged lymph nodes J:18424
enlarged spleen J:177825, J:18424
increased circulating interleukin-6 level J:177825
increased circulating serum amyloid protein level J:177825
increased granulocyte number J:177825
increased IgG1 level J:18424
increased IgG level J:177825, J:18424
increased leukocyte cell number J:18424
increased neutrophil cell number J:18424
increased plasma cell number J:177825, J:18424
increased plasmacytoid dendritic cell number J:177825
Tg(Mt1-TGFBR2*)AM3Epb/0
(involves: FVB/N)
pancreas inflammation J:76993
Tg(MT2A-TGFBR2)4Rser/0
(involves: C57BL/6 * DBA)
osteoarthritis J:44579
Tg(MtTGFA)42Lmb/Tg(MtTGFA)42Lmb
(involves: CD-1)
immune system phenotype J:28452
Tg(MUC1)79.24Gend/0
(involves: C57BL/6)
abnormal humoral immune response J:128899
increased IgG level J:154046
increased IgM level J:154046
Tg(Mup3-Plau)350-2Eps/?
(C57BL/6-Tg(Mup3-Plau)350-2Eps)
increased interleukin-1 beta secretion J:233146
increased tumor necrosis factor secretion J:233146
liver inflammation J:233146
Tg(Mx1-cre)1Cgn/0
Tg(Tal1-tTA)19Dgt/0
Tg(tetO-BCR/ABL1)2Dgt/0
TgTn(pb-sb-GrOnc)#aGsva/0

(involves: C57BL/6 * CBA/J * DBA/2 * FVB/N)
increased granulocyte number J:227558
increased leukocyte cell number J:227558
Tg(Mx1-cre)1Cgn/0
Thoc5tm1Tate/Thoc5tm1Tate

(involves: C57BL/6 * CBA)
abnormal lymphopoiesis J:169944
decreased leukocyte cell number J:169944
decreased spleen weight J:169944
Tg(Mx1-cre)1Cgn/0
Tnfrsf13ctm2.1Mass/Tnfrsf13ctm2.1Mass

(involves: C57BL/6 * CBA)
increased immature B cell number J:170519
increased pre-B cell number J:170519
increased pro-B cell number J:170519
Tg(Mx1-cre)1Cgn/0
Traf2tm1Rbr/Traf2tm1Rbr

(involves: C57BL/6 * CBA)
abnormal spleen marginal zone morphology J:93890
abnormal spleen morphology J:93890
enlarged lymph nodes J:93890
enlarged spleen J:93890
increased B cell number J:93890
increased marginal zone B cell number J:93890
Tg(Mx1-cre)1Cgn/0
U2af1tm1.1Hev/U2af1+

(involves: 129S6/SvEvTac * BALB/c * C57BL/6 * C57BL/6J * CBA/J)
decreased leukocyte cell number J:267082
Tg(Mx1-cre)1Cgn/0
U2af1tm1Mohi/U2af1tm1Mohi

(involves: C57BL/6J * CBA/J)
bone marrow failure J:308564
decreased leukocyte cell number J:308564
decreased neutrophil cell number J:308564
Tg(Mx1-cre)1Cgn/0
Zmiz1tm1c(EUCOMM)Hmgu/Zmiz1tm1c(EUCOMM)Hmgu

(involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA/J)
decreased B cell number J:234445
decreased NK cell number J:234445
decreased T cell number J:234445
thymus hypoplasia J:234445
Tg(Mx1-cre)1Cgn/0
Znrf1tm1Lchs/Znrf1tm1Lchs

(involves: C57BL/6)
decreased susceptibility to endotoxin shock J:250572
Tg(Myh6*/tetO-Capn1)L3Gwd/0
(involves: FVB/N)
heart inflammation J:133797
Tg(Myh6-BAG3*P209L)#Mswi/0
(involves: C57BL/6 * DBA/2)
heart inflammation J:234278
Tg(Myh6-Grem2)1Akh/0
(involves: C57BL/6)
decreased inflammatory response J:250034
decreased interleukin-10 secretion J:250034
Tg(Myh6-IGF1)34Pia/0
(FVB/N-Tg(Myh6-IGF1)34Pia)
increased spleen weight J:35215
Tg(Myh6-JUP*)1Dpju/0
(FVB/N-Tg(Myh6-JUP*)1Dpju)
heart inflammation J:235770
Tg(Myh6-Tnf)1Brgi/?
(involves: C57BL/6J * SJL)
myocarditis J:84829, J:100006
Tg(Myh6-Tnf)2Brgi/?
(involves: C57BL/6J * SJL)
myocarditis J:84829, J:100006
Tg(Myh6-Tnnt2*R92Q)2Lnwd/0
(involves: C57BL/6)
heart inflammation J:56911
Tg(Myh6-Tnnt2*R92Q)3Lnwd/0
(involves: C57BL/6)
heart inflammation J:56911
Tg(Myh6-tTA)6Smbf/0
Tg(tetO-EDN1,-lacZ)9Mhus/0

(involves: C57BL/6 * CBA)
heart inflammation J:131245
Tg(Myh6-tTA)6Smbf/0
Tg(tetO-HDAC5*)1Eno/0

(involves: C3H * C57BL/6 * CBA)
myocarditis J:81967
Tg(Myh6-tTA)6Smbf/0
Tg(tetO-NOS2,-lacZ)240iMhus/0

(involves: C57BL/6 * CBA)
heart inflammation J:132082
Tg(Myh6-tTA)6Smbf/0
Tg(tetO-Spp1)5Gad/0

(involves: C57BL/6 * CBA)
heart inflammation J:194810
myocarditis J:194810
Tg(Myl1-SOD1*G93A)#Amu/0
(FVB/NJ-Tg(Myl1-SOD1*G93A)#Amu)
increased microglial cell activation J:143747
Tg(Nlrp1b)1Die/0
(involves: 129S1/SvImJ * C57BL/6 * SJL)
abnormal macrophage physiology J:99748
Tg(Nr4a1-EGFP/cre)820Khog/0
(C57BL/6-Tg(Nr4a1-EGFP/cre)820Khog)
immune system phenotype J:172415
Tg(OMP-SV40T)13Bse/0
(involves: C57BL/6 * SJL)
abnormal immune tolerance J:54269
Tg(Pcp2-TBP*)69Hmhl/0
(involves: FVB/N)
brain inflammation J:174239
Tg(PF4-tTA/VP16)42Kra/0
Tg(tetO-Aurkb,lacZ)41Kra/0

(FVB/NJ-Tg(tetO-Aurkb,lacZ)41Kra Tg(PF4-tTA/VP16)42Kra)
abnormal thrombopoiesis J:104239
Tg(PF4MER)6Kra/?
(FVB/N-Tg(PF4MER)6Kra)
enlarged spleen J:35507
Tg(Pgk1-HA)1.1Vbo/?
Tg(Tcra/Tcrb)1Vbo/?

(involves: 129 * BALB/c * C57BL/6J * DBA/2J)
decreased CD4-positive, alpha-beta T cell number J:125750
increased double-positive T cell number J:125750
increased regulatory T cell number J:125750
Tg(Pgk1-HA)1.1Vbo/?
Tg(Tcra/Tcrb)1Vbo/?

(C.Cg-Tg(Pgk1-HA)1.1Vbo Tg(Tcra/Tcrb)1Vbo)
abnormal regulatory T cell physiology J:112603
increased regulatory T cell number J:112603
Tg(PGK1-KITLG*220)441Daw/Tg(PGK1-KITLG*220)441Daw
(C3H/HeJ-Tg(PGK1-KITLG*220)441Daw)
abnormal thymus morphology J:32600
Tg(Pim1-Il9)5Jcrd/0
(involves: BALB/c * FVB/N)
increased susceptibility to type I hypersensitivity reaction J:100568
Tg(Pim1-Il9)5Jcrd/0
(involves: FVB/N)
increased interleukin-5 secretion J:115764
increased susceptibility to type I hypersensitivity reaction J:100568
Tg(Pklr-HRAS*G12V)21Ak/0
(involves: C57BL/6 * DBA/2)
abnormal thymus morphology J:44803
enlarged thymus J:44803
Tg(Pklr-Myc)73Ak/0
(B6.Cg-Tg(Pklr-Myc)73Ak)
decreased NK T cell number J:184496
Tg(PLA2G2A)703Dsg/?
(involves: C57BL/6 * C57BL/6J * SJL)
immune system phenotype J:113573
Tg(PLP1*)4Rsj/0
(involves: CD-1)
CNS inflammation J:161344
Tg(Plp1-Eif2ak3*)18Pop/0
(C57BL/6J-Tg(Plp1-Eif2ak3*)18Pop)
decreased susceptibility to experimental autoimmune encephalomyelitis J:238042
Tg(Plp1-LMNB1)1108Qsp/0
(involves: FVB/N)
microgliosis J:226169
Tg(Plp1-SNCA)1Haa/0
(involves: C57BL/6 * DBA/2)
microgliosis J:96778
Tg(PML-RARA)556Kog/?
(involves: FVB/N)
abnormal neutrophil differentiation J:39327
Tg(PML-RARA)556Kog/0
(FVB/N-Tg(PML-RARA)556Kog)
enlarged spleen J:262172
increased leukocyte cell number J:262172
Tg(PMP22)C61Clh/0
(B6.Cg-Tg(PMP22)C61Clh)
increased macrophage cell number J:158350
Tg(Prdx6)153Pgn/0
(C57BL/6-Tg(Prdx6)153Pgn/Pgn)
abnormal macrophage physiology J:86528
Tg(PRG1)18Wlad/0
(involves: C57BL/6J * CBA/J)
decreased susceptibility to Picornaviridae infection J:127826
increased susceptibility to Picornaviridae infection J:92990
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:92990
Tg(PRG3)9Wlad/0
(involves: C57BL/6J * CBA/J)
increased susceptibility to Picornaviridae infection J:92990, J:127826
Tg(Prnp)4053Sbp/0
(involves: FVB/N)
increased susceptibility to prion infection J:136434
Tg(Prnp)a20Cwe/0
(Not Specified)
increased susceptibility to prion infection J:130657, J:143528
Tg(Prnp-APP*)1Hmor/0
(B6.Cg-Tg(Prnp-APP*)1Hmor)
microgliosis J:159623
Tg(Prnp-ATXN7*92Q)6529Als/Y
(involves: C3H/HeJ * C57BL/6J)
colitis J:135615
Tg(Prnp-FUS)WT3Cshw/0
(involves: C57BL/6 * Crl:CD-1(ICR))
microgliosis J:189360
Tg(Prnp-FUS)WT3Cshw/Tg(Prnp-FUS)WT3Cshw
(involves: C57BL/6 * Crl:CD-1(ICR))
microgliosis J:189360
Tg(Prnp-Immt/SOD1*G93A)7Gmnf/Tg(Prnp-Immt/SOD1*G93A)7Gmnf
(involves: C57BL/6 * CBA * SJL)
dermatitis J:177846
Tg(Prnp-ITM2B*)1Ruvi/Tg(Prnp-ITM2B*)1Ruvi
Tg(Prnp-MAPT*P301L)#Ruvi/Tg(Prnp-MAPT*P301L)#Ruvi

(involves: C3HeB/FeJ * C57BL/6)
increased inflammatory response J:197198
Tg(Prnp-ITM2B*)7Jckr/0
(C57BL/6-Tg(Prnp-ITM2B*)7Jckr)
microgliosis J:159279
Tg(Prnp-MAPT*P301L)JNPL3Hlmc/?
(involves: C57BL/6 * DBA/2)
eye inflammation J:63887
Tg(Prnp-MAPT*R406W)21807Dwst/?
(FVB/N-Tg(Prnp-MAPT*R406W)21807Dwst)
microgliosis J:95971
Tg(Prnp-PFN1*C71G)22Zxu/0
Tg(Thy1-PFN1*C71G)67Zxu/Tg(Thy1-PFN1*C71G)67Zxu

(involves: FVB/N)
microgliosis J:235427
Tg(Prnp-TARDBP)96Dwc/0
Tg(Prnp-TARDBP*Q331K)31Dwc/0

(involves: C3H * C57BL/6)
microgliosis J:239141
Tg(Prnp-TARDBP*Q331K)31Dwc/?
(involves: C3H * C57BL/6)
microgliosis J:239141
Tg(Prox1-EGFP)KY221Gsat/0
(involves: FVB/NTac)
abnormal lymphangiogenesis J:235778
abnormal lymphatic vessel endothelial cell morphology J:235778
Tg(Psp-Rbbp4)1Yoha/0
(involves: C57BL/6)
abnormal antigen presentation J:141378
abnormal T cell activation J:141378
increased autoantibody level J:141378
increased interferon-gamma secretion J:141378
increased interleukin-2 secretion J:141378
increased interleukin-18 secretion J:141378
increased marginal zone B cell number J:141378
increased susceptibility to autoimmune disorder J:141378
lacrimal gland inflammation J:141378
salivary gland inflammation J:141378
Tg(PTH-CCND1)PC2Anar/0
(FVB/N-Tg(PTH-CCND1)PC2Anar)
increased osteoclast cell number J:69423
Tg(PVR)1Kkst/0
(involves: ICR)
increased susceptibility to Picornaviridae infection J:153943
Tg(RIP1-Tag)5Dh/?
(C3HeB/FeJ-Tg(RIP1-Tag)5Dh)
pancreas inflammation J:80168
Tg(rv-CYCLIN)29Dlh/0
(involves: C57BL/6 * SJL)
lymphoid hyperplasia J:62478
spleen hyperplasia J:62478
Tg(Scgb1a1-IL6)9Flv/0
(involves: C57BL/6 * CBA)
lung inflammation J:128762, J:156430
Tg(Scgb1a1-Il13)2Eli/?
(involves: C57BL/6 * CBA)
abnormal leukocyte physiology J:53612
respiratory system inflammation J:53612
Tg(Scgb1a1-Il17a)3Cdon/0
(C57BL/6-Tg(Scgb1a1-Il17a)3Cdon)
abnormal chemokine level J:112600
lung inflammation J:112600
Tg(Scgb1a1-Il17f,GFP)1Cdon/?
(C57BL/6-Tg(Scgb1a1-Il17f,GFP)1Cdon)
lung inflammation J:136279
Tg(Scgb1a1-Muc5b,-AcGFP)#Evns/0
(involves: C57BL/6J * C57BL/6N)
decreased susceptibility to bacterial infection J:207159
Tg(Scgb1a1-PLUNC)#Chuh/0
(involves: FVB/N)
decreased susceptibility to bacterial infection J:171589
Tg(Scgb1a1-rtTA)1Jaw/0
Tg(tetO-Aimp1)29872Mcla/0

(involves: 129 * C57BL/6)
increased macrophage cell number J:173904
Tg(Scgb1a1-rtTA)1Jaw/0
Tg(tetO-EGFR*T790M*L858R)19Kkw/0

(involves: 129 * C57BL/6 * FVB/N)
interstitial pneumonia J:122849
Tg(Scgb1a1-rtTA)1Jaw/0
Tg(tetO-IL1B)KBry/0

(involves: 129 * C57BL/6)
abnormal chemokine level J:107601, J:130523
lung inflammation J:107601, J:130523
Tg(Scgb1a1-rtTA,-tTS,tetO-CHI3L1)1Eli/0
(Not Specified)
abnormal macrophage morphology J:148490
decreased T cell apoptosis J:148490
increased T-helper 2 cell number J:148490
Tg(Scgb1a1-rtTA,-tTS,tetO-TGFB1*)1Eli/0
(involves: C57BL/6)
lung inflammation J:92469
Tg(Scgb1a1-rtTA,tetO-Ifng)14Eli/0
(involves: C57BL/6 * CBA)
increased lymphocyte cell number J:100854
increased macrophage cell number J:100854
increased neutrophil cell number J:100854
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli/0
(involves: C57BL/6 * CBA)
abnormal T-helper 2 physiology J:148490
increased T-helper 2 cell number J:148490
Tg(Scgb1a1-Scnn1b)6608Bouc/0
(involves: C3H * C57BL/6)
bronchitis J:91139
Tg(Scgb1a1-Scnn1b)6608Bouc/0
(B6.Cg-Tg(Scgb1a1-Scnn1b)6608Bouc)
respiratory system inflammation J:191673
Tg(Scgb1a1-Scnn1b)6608Bouc/0
(C.Cg-Tg(Scgb1a1-Scnn1b)6608Bouc)
respiratory system inflammation J:191673
Tg(SERPINA1*E342K)#Slcw/0
(involves: C57BL/6 * ICR)
liver inflammation J:149132
Tg(SERPINA1-HBVX)1655Jtsb/0
(involves: C3H * C57BL/6 * ICR)
liver inflammation J:90305
Tg(SERPINA1-IGHG1/Il1rl1)423Zbz/?
(involves: C3H * C57BL/6)
abnormal eosinophil physiology J:63507
abnormal response to infection J:63507
decreased interleukin-5 secretion J:63507
increased eosinophil cell number J:63507
X/Tg(SERPINC1-SV40)BPbr
(involves: C57BL/6 * DBA/2)
increased macrophage cell number J:84204
Tg(SFTPC-DPP4)3Pbmj/0
(involves: C57BL/6J * SJL/J)
abnormal susceptibility to Coronaviridae infection J:285467
Tg(SFTPC-Il18)AThos/0
(B6N.Cg-Tg(SFTPC-Il18)AThos)
abnormal spleen morphology J:147547
enlarged spleen J:147547
increased interferon-gamma secretion J:147547
increased interleukin-13 secretion J:147547
lung inflammation J:147547
Tg(SFTPC-rtTA)2Jaw/0
Tg(tetO-CTGF)#Swu/0

(involves: 129 * C57BL/6 * C57BL/6J)
lung inflammation J:171151
Tg(SFTPC-rtTA,tetO-Tnf)320-1Gwho/0
(involves: C57BL/6 * SJL)
abnormal B cell morphology J:97297
abnormal bronchus-associated lymphoid tissue morphology J:97297
abnormal CD4-positive, alpha beta T cell morphology J:97297
abnormal dendritic cell morphology J:97297
abnormal T cell morphology J:97297
increased CD8-positive, alpha-beta T cell number J:97297
increased lymphocyte cell number J:97297
increased neutrophil cell number J:97297
lung inflammation J:97297
Tg(SFTPC-Tnf)2Pva/0
(involves: C57BL/6 * DBA/2)
alveolitis J:28120
interstitial pneumonia J:28120
Tg(Sirt1)ASrn/?
(involves: C57BL/6 * CBA)
increased susceptibility to endotoxin shock J:137868
Tg(SOD1*G93A)1Gur/0
(B6.Cg-Tg(SOD1*G93A)1Gur/J)
abnormal spleen morphology J:138237
abnormal T cell physiology J:138237
decreased spleen weight J:138237
decreased splenocyte number J:138237
Tg(SOD1*G93A)1Gur/0
(B6SJL-Tg(SOD1*G93A)1Gur/J)
abnormal lymphocyte morphology J:129215
abnormal microglial cell morphology J:165019, J:143173
abnormal spleen morphology J:138237
abnormal splenic cell ratio J:138237
abnormal splenocyte morphology J:138237
CNS inflammation J:110437
decreased eosinophil cell number J:129215
decreased leukocyte cell number J:129215
decreased lymphocyte cell number J:129215
decreased monocyte cell number J:129215
decreased spleen weight J:138237
increased basophil cell number J:129215
microgliosis J:146652, J:165019, J:110437, J:143173
small spleen J:138237
Tg(SOD1*G93A)dl1Gur/0
(involves: C57BL/6 * C57BL/6J * SJL/J)
microgliosis J:128738
Tg(SOD1*H46R)LAra/0
(involves: C57BL/6 * DBA/2)
microgliosis J:221350
Tg(SOD1*H46R*C111S)PAra/0
(involves: C57BL/6 * DBA/2)
microgliosis J:221350
Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
(involves: C57BL/6 * DBA/2)
microgliosis J:221350
Tg(SOD1*H46R*C111S)QAra/0
(involves: C57BL/6 * DBA/2)
microgliosis J:221350
Tg(SOD1*L126Z)45Dbo/0
(involves: C3H/HeJ * C57BL/6J)
microgliosis J:219482
Tg(Stat3*)9199Alau/0
(involves: C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:210877
abnormal T-helper 17 cell differentiation J:210877
decreased IgG1 level J:210877
decreased IgG3 level J:210877
increased IgE level J:210877
increased inflammatory response J:210877
increased neutrophil cell number J:210877
increased susceptibility to bacterial infection J:210877
increased susceptibility to bacterial infection induced morbidity/mortality J:210877
increased susceptibility to endotoxin shock J:210877
intestinal inflammation J:210877
Tg(SV40-Ahr)1Poe/0
(involves: C57BL/6 * CBA)
absent B-1a cells J:82428
decreased B-1 B cell number J:82428
decreased thymus weight J:77977
increased B-2 B cell number J:82428
increased mature B cell number J:82428
increased pre-B cell number J:82428
increased pro-B cell number J:82428
Tg(SV40-Igh-64C8)H3Hon/0
Tg(SV40-Igk4C8)L1Hon/0

(involves: C57BL/6)
abnormal B cell clonal deletion J:139864
abnormal B cell number J:139864
increased anti-erythrocyte antigen antibody level J:139864
Tg(SV40-KLK7)1010Teg/0
(involves: C57BL/6J * CBA)
dermatitis J:75714
Tg(SV40/HTLV-FCER1A)1Bhk/0
(involves: 129)
immune system phenotype J:47138
Tg(SV)427Bri/0
(C57BL/6J-Tg(SV)427Bri)
enlarged thymus J:79096
Tg(TARDBP)#Jpj/0
(involves: C3H * C57BL/6)
microgliosis J:195184
Tg(TARDBP*A315T)#Jpj/0
(involves: C3H * C57BL/6)
microgliosis J:195184
Tg(TARDBP*G348C)#Jpj/0
(involves: C3H * C57BL/6)
abnormal cytokine level J:195184
microgliosis J:195184
Tg(TCF3/HLF)1Mlc/0
(involves: FVB/N)
abnormal CD4-positive, alpha beta T cell morphology J:55022
abnormal thymus involution J:55022
arrested T cell differentiation J:55022
decreased CD4-positive, alpha-beta T cell number J:55022
decreased CD8-positive, alpha-beta T cell number J:55022
decreased double-positive T cell number J:55022
decreased T cell number J:55022
decreased thymocyte number J:55022
thymus hypoplasia J:55022
Tg(Tcra2B4)1Mmd/?
(involves: C3H/HeJ * C57BL/6)
abnormal thymus cell ratio J:92992
decreased CD4-positive, alpha-beta T cell number J:92992
decreased double-positive T cell number J:92992
decreased thymocyte number J:92992
increased double-negative T cell number J:92992
Tg(Tcra2C,Tcrb2C)1Dlo/?
(involves: C57BL/6 * SJL)
abnormal CD8-positive, alpha beta T cell morphology J:125259
Tg(Tcra2C,Tcrb2C)1Dlo/?
(involves: C57L * DBA/2 * SJL)
abnormal memory T cell physiology J:95380
decreased lymphocyte cell number J:95380
decreased thymocyte number J:95380
increased CD4-positive, alpha-beta T cell number J:95380
seborrheic dermatitis J:95380
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
(involves: C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:83278
abnormal cytokine secretion J:83278
blepharitis J:83278
CNS inflammation J:83278
increased susceptibility to autoimmune disorder J:83278
increased susceptibility to experimental autoimmune encephalomyelitis J:83278
Tg(Tcra2D2,Tcrb2D2)1Kuch/?
(involves: C57BL/6 * CD-1)
decreased interleukin-17 secretion J:125296
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T-helper 1 cell number J:189919
decreased interferon-gamma secretion J:189919
decreased interleukin-2 secretion J:189919
decreased interleukin-10 secretion J:189919
decreased T cell proliferation J:189919
decreased T-helper 2 cell number J:189919
decreased T-helper 17 cell number J:189919
increased interferon-gamma secretion J:189919
increased interleukin-6 secretion J:189919
increased interleukin-17 secretion J:189919
increased T cell apoptosis J:189919
increased T cell proliferation J:189919
Tg(Tcra5CC7,Tcrb5CC7)IWep/0
(involves: C57BL/6)
abnormal T cell activation J:73608
Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr/0
(involves: C57BL/6 * DBA/2)
abnormal positive T cell selection J:125548
Tg(Tcra,Tcrb)3Ayr/0
(involves: C57BL/6 * DBA/2)
abnormal lymphocyte anergy J:80775
abnormal positive T cell selection J:125548
decreased T cell proliferation J:80775
Tg(Tcra,Tcrb)24Efro/0
(D1.Cg-Tg(Tcra,Tcrb)24Efro)
abnormal cytokine secretion J:104243
abnormal T cell differentiation J:104243
autoimmune response J:104243
decreased T cell proliferation J:104243
increased autoantibody level J:104243
increased memory T cell number J:104243
increased susceptibility to autoimmune disorder J:104243
increased T cell proliferation J:104243
Tg(Tcra,Tcrb)HRCAll/0
(B6.Cg-Tg(Tcra,Tcrb)HRCAll)
abnormal T cell subpopulation ratio J:131347
decreased CD4-positive, alpha-beta T cell number J:131347
decreased cytotoxic T cell cytolysis J:131347
decreased interferon-gamma secretion J:131347
increased CD8-positive, alpha-beta T cell number J:131347
Tg(Tcra,Tcrb)HRVAll/0
(B6.Cg-Tg(Tcra,Tcrb)HRVAll)
abnormal T cell subpopulation ratio J:131347
decreased CD4-positive, alpha-beta T cell number J:131347
increased CD8-positive, alpha-beta T cell number J:131347
Tg(TcraAI4)1Dvs/0
(NOD-Tg(TcraAI4)1Dvs)
abnormal CD4-positive, alpha beta T cell morphology J:93553
increased susceptibility to autoimmune diabetes J:93553
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0

(NOD-Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs)
abnormal CD4-positive, alpha beta T cell morphology J:93553
abnormal CD8-positive, alpha beta T cell morphology J:94192
abnormal cytotoxic T cell physiology J:94192
increased susceptibility to autoimmune diabetes J:94192
Tg(TcraAV19AJ33)1Shima/?
(involves: 129S4/SvJae * C57BL/6)
abnormal NK T cell morphology J:112657
abnormal NK T cell physiology J:112657
decreased susceptibility to experimental autoimmune encephalomyelitis J:112657
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0
(NOD.Cg-Tg(TcraBDC2.5,TcrbBDC2.5)1Doi)
decreased susceptibility to autoimmune diabetes J:87251
increased activated T cell number J:52940
insulitis J:52940
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0
(involves: C57BL/6 * NOD * SJL)
decreased dendritic cell number J:137009
immune system phenotype J:135214
insulitis J:137009
Tg(TcraCl1,TcrbCl1)1Shrm/0
(B10.Cg-Thy1a H2d Tg(TcraCl1,TcrbCl1)1Shrm)
abnormal T cell subpopulation ratio J:97745
Tg(TcraCl4,TcrbCl4)1Shrm/?
(B10.Cg-H2d Tg(TcraCl4,TcrbCl4)1Shrm)
abnormal CD8-positive, alpha-beta T cell differentiation J:99756
abnormal T cell subpopulation ratio J:99756
Tg(TcraDN32D3)#Alhn/0
(involves: NOD)
decreased NK cell number J:201417
decreased thymocyte number J:201417
increased double-negative T cell number J:201417
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
(involves: C57BL/6J * C57L/J * DBA/2J)
abnormal double-negative T cell morphology J:79738
abnormal T cell differentiation J:79738, J:90776
decreased thymocyte number J:79738
thymus hypoplasia J:79738
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
(involves: C57BL/6 * DBA/2J)
abnormal cytotoxic T cell physiology J:66565
abnormal T cell differentiation J:97610
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
Themistm1Gasc/Themistm1Gasc

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal negative T cell selection J:151074
abnormal positive T cell selection J:151074
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
Themistm1Lov/Themistm1Lov

(involves: 129 * C57BL/6 * DBA/2)
abnormal negative T cell selection J:151075
abnormal positive T cell selection J:151075
decreased single-positive T cell number J:151075
increased double-positive T cell number J:151075
Tg(TcraH-Y,TcrbH-Y)71Vbo/0
Tnfrsf25tm1Mjo/Tnfrsf25tm1Mjo

(involves: 129P2/OlaHsd * C57BL/6J * DBA/2J)
abnormal negative T cell selection J:84536
abnormal thymus morphology J:84536
increased thymocyte number J:84536
Tg(TcrAND)53Hed/?
(involves: A/WySnSg * C57BL/6 * C57BL/10SnSg * SJL)
abnormal positive T cell selection J:85777
abnormal T cell differentiation J:85777
abnormal T cell proliferation J:85777
abnormal T cell subpopulation ratio J:85777
abnormal thymocyte activation J:85777
decreased CD8-positive, alpha-beta T cell number J:85777
decreased double-positive T cell number J:85777
increased CD4-positive, alpha-beta T cell number J:85777
Tg(TcrAND)53Hed/?
(involves: C57BL/6 * SJL)
abnormal lymph node cell ratio J:124701
increased CD4-positive, alpha-beta T cell number J:124701
Tg(TcrAND)53Hed/?
Themistm1Gasc/Themistm1Gasc

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
abnormal positive T cell selection J:151074
decreased CD4-positive, alpha-beta T cell number J:151074
decreased CD8-positive, alpha-beta T cell number J:151074
increased double-positive T cell number J:151074
Tg(TcrAND)53Hed/?
Themistm1Lov/Themistm1Lov

(involves: 129 * C57BL/6 * SJL)
abnormal positive T cell selection J:151075
decreased single-positive T cell number J:151075
increased double-positive T cell number J:151075
Tg(TcrAND)53Hed/?
Zbtb7btm1.1Rbo/Zbtb7btm1.1Rbo

(involves: C57BL/6 * SJL)
abnormal T cell differentiation J:141145
Tg(TcraR28,TcrbR28)KRNDim/0
(involves: C57BL/6 * NOD * SJL)
abnormal lymphocyte cell number J:36815
abnormal macrophage chemotaxis J:36815
abnormal T cell activation J:36815
abnormal T cell anergy J:36815
abnormal T cell clonal deletion J:36815
abnormal T cell proliferation J:36815
chronic joint inflammation J:36815
decreased CD4-positive, alpha-beta T cell number J:36815
decreased CD8-positive, alpha-beta T cell number J:36815
enlarged spleen J:36815
glomerulonephritis J:36815
impaired neutrophil recruitment J:36815
increased B cell number J:36815
increased IgG1 level J:36815
kidney inflammation J:36815
rheumatoid arthritis J:36815
Tg(TcraTcrb)8Rest/?
(C57BL/6-Tg(TcraTcrb)8Rest)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:85058
abnormal cytotoxic T cell physiology J:85058
increased interferon-gamma secretion J:85058
Tg(TcraTcrb)425Cbn/0
(involves: BALB/c * C57BL/6)
abnormal positive T cell selection J:125548
Tg(TcraTcrb)425Cbn/?
(involves: BALB/c * C57BL/6)
abnormal positive T cell selection J:87876
increased CD4-positive, alpha-beta T cell number J:87876
Tg(TcraTcrb)425Cbn/0
(involves: C57BL/6)
abnormal cytokine level J:112600
Tg(TcraTcrb)425Cbn/0
Trim30atm1Yjk/Trim30atm1Yjk

(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
increased T cell proliferation J:215171
Tg(TcraTcrb)425Cbn/0
Trip10tm1.1Geha/Trip10tm1.1Geha

(B6.Cg-Trip10tm1.1Geha Tg(TcraTcrb)425Cbn)
abnormal effector T cell morphology J:164363
decreased CD4-positive, alpha-beta T cell number J:164363
immune system phenotype J:164363
Tg(TcraTcrb)1100Mjb/?
(involves: C57BL/6)
abnormal CD8-positive, alpha beta T cell morphology J:92867
abnormal cytotoxic T cell physiology J:92867, J:133645
abnormal positive T cell selection J:92867, J:133645
abnormal T cell clonal deletion J:92867
abnormal T cell subpopulation ratio J:92867, J:133645
decreased CD4-positive, alpha-beta T cell number J:133645
increased CD8-positive, alpha-beta T cell number J:92867, J:133645
increased T cell proliferation J:92867
Tg(TcraTcrb)1100Mjb/?
(involves: C57BL/6 * MRL/Mp)
liver inflammation J:72817
Tg(TcraTcrb)1100Mjb/?
Themistm1Gasc/Themistm1Gasc

(involves: 129S6/SvEvTac * C57BL/6)
abnormal positive T cell selection J:151074
decreased CD8-positive, alpha-beta T cell number J:151074
increased double-positive T cell number J:151074
Tg(TcraTcrbNY4.1)1Pesa/0
(NOD.Cg-Tg(TcraTcrbNY4.1)1Pesa)
increased susceptibility to autoimmune diabetes J:108768
insulitis J:108768
Tg(TcraTcrbNY8.3)1Pesa/?
(involves: C57BL/6 * NOD * SJL)
pancreas inflammation J:44202
Tg(TcraY1,TcrbY1)416Tev/0
(involves: C57BL/6J * DBA/2J)
abnormal immune tolerance J:84288
Tg(Tcrb)93Vbo/0
(involves: C57BL/LiA * CBA/BrA)
abnormal T cell morphology J:93247
abnormal T cell receptor beta chain V(D)J recombination J:93247
Tg(Tcrb)93Vbo/0
(involves: C57BL/6 * C57BL/LiA * CBA/BrA)
abnormal CD8-positive, alpha-beta T cell differentiation J:66565
abnormal cytotoxic T cell physiology J:66565
abnormal T cell clonal deletion J:66565
Tg(Tcrb)HRBAll/0
(B6.Cg-Tg(Tcrb)HRBAll)
immune system phenotype J:131347
Tg(Tcrb-TCF3/PBX1)19Gusa/0
(involves: C3H * C57BL/6 * C57BL/6J)
decreased thymocyte number J:95693
Tg(Tcrb-TCF3/PBX1)23Gusa/0
(involves: C3H * C57BL/6 * C57BL/6J)
decreased thymocyte number J:95693
Tg(TcrbAI4)1Dvs/0
(NOD-Tg(TcrbAI4)1Dvs)
abnormal CD4-positive, alpha beta T cell morphology J:93553
Tg(TcrbBL17)1Lmor/0
(involves: DBA/1J * SWR/J)
increased susceptibility to induced arthritis J:134111
Tg(TcrbBL17)1Lmor/Tg(TcrbBL17)1Lmor
(involves: DBA/1J * SWR/J)
increased susceptibility to induced arthritis J:134111
Tg(TcrHEL3A9)1Mmd/0
(involves: C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:73608
abnormal interleukin secretion J:73608
abnormal T cell activation J:73608
increased T cell proliferation J:73608
Tg(TcrHEL3A9)1Mmd/0
(involves: C57BL/6 * C57BL/10 * C57BR/cd)
abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal double-positive T cell morphology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
abnormal thymus cell ratio J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
Tg(TcrHEL3A9)1Mmd/0
Tg(TLK2mHEL)2Ccg/0

(involves: C57BL/6 * C57BL/10 * C57BR/cd)
abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal CD4-positive, alpha-beta T cell physiology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
decreased double-positive T cell number J:78309
thyroid gland inflammation J:78309
Tg(TcrLCMV)1Aox/?
(C57BL/6-Tg(TcrLCMV)1Aox)
abnormal cytotoxic T cell physiology J:92228
decreased CD8-positive, alpha-beta T cell number J:92228
decreased double-positive T cell number J:92228
increased CD4-positive, alpha-beta T cell number J:92228
increased double-negative T cell number J:92228
increased IgG level J:92228
Tg(TcrLCMV)2Aox/?
(C57BL/6-Tg(TcrLCMV)2Aox)
abnormal cytotoxic T cell physiology J:92228
decreased CD8-positive, alpha-beta T cell number J:92228
decreased double-positive T cell number J:92228
increased CD4-positive, alpha-beta T cell number J:92228
increased double-negative T cell number J:92228
Tg(TcrLCMV)327Sdz/0
(involves: C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:77696
decreased cytotoxic T cell cytolysis J:77696
decreased double-positive T cell number J:77696
decreased T cell proliferation J:77696
thymus hypoplasia J:77696
Tg(TcrLCMV)327Sdz/?
(involves: C57BL/6 * DBA/2J)
abnormal T cell differentiation J:97610
decreased CD4-positive, alpha-beta T cell number J:97610
Tg(TcrLCMV)327Sdz/Tg(TcrLCMV)327Sdz
(NOD.Cg-Tg(TcrLCMV)327Sdz/Dvs)
autoimmune response J:71050
Tg(Tek-cre)1Ywa/0
Thbdtm2Rdr/Thbdtm2Wlr

(involves: 129S2/SvPas * C57BL/6 * SJL)
abnormal acute phase protein level J:71269
increased circulating interleukin-6 level J:71269
increased spleen weight J:71269
Tg(Tek-Jam3)1Maal/?
(B6.Cg-Tg(Tek-Jam3)1Maal)
abnormal cellular extravasation J:99020
abnormal leukocyte adhesion J:99020
abnormal leukocyte physiology J:99020
impaired neutrophil chemotaxis J:99020
lung inflammation J:99020
peritoneal inflammation J:99020
Tg(Tek-Procr)1Cte/0
(B6.FVB-Tg(Tek-Procr)1Cte)
abnormal acute phase protein level J:119637
abnormal immune system physiology J:119637
abnormal inflammatory response J:119637
Tg(Tek-Tnf*)5382Mcla/0
(B6.Cg-Tg(Tek-Tnf*)5382Mcla)
chronic inflammation J:71622
chronic liver inflammation J:71622
decreased inflammatory response J:71622
kidney inflammation J:71622
lung inflammation J:71622
Tg(Tek-tTA)1Dmt/0
Tg(tetO-Tek)1Dmt/0

(involves: CD-1)
abnormal spleen red pulp morphology J:137745
abnormal spleen white pulp morphology J:137745
enlarged spleen J:137745
increased eosinophil cell number J:137745
increased T cell number J:137745
skin inflammation J:96718, J:137745
Tg(tetO-BCR/ABL1)2Dgt/0
Tg(MMTVtTA)1Mam/0

(involves: C57BL/6 * FVB/N * SJL)
enlarged lymph nodes J:72377
enlarged spleen J:72377
increased leukocyte cell number J:72377
Tg(tetO-BCR/ABL1)2Dgt/0
Tg(Tal1-tTA)19Dgt/0

(involves: C57BL/6 * DBA/2 * FVB/N)
abnormal lymph node morphology J:96511
abnormal lymphopoiesis J:96511
abnormal spleen red pulp morphology J:96511
abnormal splenic cell ratio J:96511
enlarged spleen J:96511
increased leukocyte cell number J:96511
increased neutrophil cell number J:96511
Tg(tetO-BCR/ABL1)27Dgt/0
Tg(MMTVtTA)1Mam/0

(involves: C57BL/6 * FVB/N * SJL)
enlarged lymph nodes J:72377
enlarged spleen J:72377
increased leukocyte cell number J:72377
Tg(tetO-MAP2K1)#Ahsa/?
Tg(CD2-rtTA)CRza/?

(involves: C57BL/6 * C57BL/10 * CBA * SJL)
immune system phenotype J:174339
increased anti-double stranded DNA antibody level J:174339
Tg(tetO/CMV-CD200)1Rmgo/Tg(tetO/CMV-CD200)1Rmgo
(involves: C57BL/6)
abnormal dendritic cell physiology J:134313
Tg(TetOp-Polb/tTA)2Sbl/0
(B6.Cg-Tg(TetOp-Polb/tTA)2Sbl)
glomerulonephritis J:152481
Tg(TG-SV40)#Cled/0
(involves: C57BL/6J * DBA/2J)
spleen hypoplasia J:209788
thymus hypoplasia J:209788
Tg(TG-TSHR)51.9Smcl/?
(involves: BALB/c * C57BL/6)
immune system phenotype J:118100
Tg(Tgfa)1Efu/0
(Not Specified)
ear inflammation J:65045
Tg(Th-SNCA)5Eric/Tg(Th-SNCA)5Eric
(involves: C57BL/6)
abnormal microglial cell physiology J:140907
Tg(THY1-APP)2Somm/0
(involves: C57BL/6J * DBA/2)
brain inflammation J:44603
Tg(Thy1-APP)3Somm/0
(involves: C57BL/6J * DBA/2)
brain inflammation J:44603
microgliosis J:134832
Tg(Thy1-App*R609D*K612E)2Vln/0
(involves: C57BL * CBA/J)
abnormal microglial cell morphology J:32213
Tg(Thy1-App*R609D*K612E)4Vln/0
(involves: FVB)
abnormal microglial cell morphology J:32213
Tg(Thy1-App*R609D*K612E)6Vln/0
(involves: FVB)
abnormal microglial cell morphology J:32213
Tg(Thy1-APPDutch)#Jckr/0
(involves: C57BL/6J)
microgliosis J:92796
Tg(Thy1-APPSw)10Jiri/0
(involves: C3H * C57BL/6)
microgliosis J:128647
Tg(Thy1-APPSw)10Jiri/0
Tg(Thy1-PSEN1*M146V)#Jiri/0

(B6.Cg-Tg(Thy1-APPSw)10Jiri Tg(Thy1-PSEN1*M146V)#Jiri)
microgliosis J:156577
Tg(Thy1-APPSwDutIowa)BWevn/0
(involves: C57BL/6)
abnormal microglial cell physiology J:124911
Tg(Thy1-APPSweLon)41Ema/0
(involves: C57BL/6 * DBA/2)
microgliosis J:162842
Tg(Thy1-Fcer2a)2431Putt/?
(involves: BALB/c * C57BL/6)
abnormal immune system physiology J:129296
decreased IgE level J:20421
decreased IgG1 level J:20421
increased eosinophil cell number J:20421
Tg(Thy1-Fcer2a)2733Putt/?
(involves: BALB/c * C57BL/6)
immune system phenotype J:20421
Tg(Thy1-FUS*)1Dit/0
(B6.Cg-Tg(Thy1-FUS*)1Dit)
microgliosis J:287782
Tg(Thy1-FUS*)1Dit/0
Tg(Thy1-TARDBP)4Singh/0

(involves: C57BL/6J * DBA/2J * SJL/J)
microgliosis J:287782
Tg(Thy1-FUS*)19Vlb/0
(B6.Cg-Tg(Thy1-FUS*)19Vlb)
microgliosis J:203550
Tg(Thy1-MAPT*)1Avil/Tg(Thy1-MAPT*)1Avil
(involves: C57BL/6 * CBA)
microgliosis J:201700
Tg(Thy1-MAPT*P301S)2541Godt/Tg(Thy1-MAPT*P301S)2541Godt
(involves: C57BL/6J * CBA/Ca)
eye inflammation J:108870
Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
(involves: C57BL/6 * CBA)
microgliosis J:155410
Tg(Thy1-Snca)1S13Putt/?
(involves: C57BL/6)
microgliosis J:177661
Tg(Thy1-SNCA)61Ema/0
(involves: C57BL/6 * DBA/2)
abnormal microglial cell activation J:238066
abnormal microglial cell morphology J:238066
Tg(Thy1-Sncg)HvP36Putt/?
(C57BL/6-Tg(Thy1-Sncg)HvP36Putt)
microgliosis J:185793
Tg(Thy1-TARDBP)4Singh/0
(involves: C57BL/6J * SJL/J)
microgliosis J:157550
Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh
(involves: C57BL/6J * SJL/J)
microgliosis J:157550
Tg(Thy1-TARDBP)6Singh/Tg(Thy1-TARDBP)6Singh
(involves: C57BL/6 * C57BL/6J * SJL)
microgliosis J:157550
Tg(Thy1-UBQLN2*P497S)3Mont/?
(involves: C3H * C57BL/6 * C57BL/6J)
increased microglial cell activation J:239510
Tg(Thy1-UBQLN2*P506T)6Mont/?
(involves: C3H * C57BL/6 * C57BL/6J)
decreased microglial cell activation J:239510
Tg(Thy1/THY1)T6Gsv/0
(involves: C57BL/10 * CBA)
abnormal mononuclear cell morphology J:294621
increased macrophage derived foam cell number J:294621
increased neutrophil cell number J:294621
Tg(Thy1/THY1)T12Gsv/0
(involves: C57BL/10 * CBA)
increased IgG level J:133943
increased IgM level J:133943
Tg(Tk1-DPP4)27Ysj/0
(involves: C57BL/6 * FVB/N)
abnormal chemokine level J:290259
abnormal innate immunity J:290259
abnormal interleukin level J:290259
abnormal macrophage activation involved in immune response J:290259
abnormal tumor necrosis factor level J:290259
increased susceptibility to Coronaviridae infection J:290259
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:290259
lung inflammation J:290259
Tg(Tlr7)1Boll/0
(involves: C57BL/6)
abnormal circulating chemokine level J:127600
abnormal dendritic cell morphology J:127600
abnormal spleen morphology J:127600
autoimmune response J:127600
decreased spleen white pulp amount J:127600
enlarged spleen J:127600
glomerulonephritis J:127600
increased anti-nuclear antigen antibody level J:127600
increased circulating interleukin-6 level J:127600
increased circulating tumor necrosis factor level J:127600
liver inflammation J:127600
X/Tg(Tlr7)6Boll
(involves: C57BL/6)
abnormal B cell activation J:127600
abnormal B cell morphology J:127600
abnormal dendritic cell morphology J:127600
abnormal T cell activation J:127600
autoimmune response J:127600
decreased marginal zone B cell number J:127600
enlarged spleen J:127600
glomerulonephritis J:127600
increased anti-nuclear antigen antibody level J:127600
increased mature B cell number J:127600
increased splenocyte proliferation J:127600
liver inflammation J:127600
lung inflammation J:127600
Tg(TNF)197Gkl/0
(involves: C57BL/6 * CBA)
abnormal osteoclast differentiation J:97992
arthritis J:97992, J:92576
increased osteoclast cell number J:97992
Tg(TNF)197Gkl/0
Tnfrsf1atm1.1Gkl/Tnfrsf1atm1.1Gkl

(involves: 129 * C57BL/6 * CBA)
arthritis J:92470
Tg(TNF)3647Gkl/0
(involves: C57BL/6 * CBA)
arthritis J:190204
Tg(Tnf)6074Gkl/0
(involves: C57BL/6 * CBA)
abnormal microglial cell morphology J:106592
brain inflammation J:106592
Tg(Tnf)6074Gkl/0
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm

(involves: 129S2/SvPas * C57BL/6 * CBA)
CNS inflammation J:106592
Tg(TNFSF11)5516Edou/0
Tnfsf11tles/Tnfsf11tles

(involves: 129S6/SvEvTac * C57BL/6J * CBA/J)
absent lymph nodes J:233240
Tg(TNFSF11)5519Edou/0
(involves: C57BL/6J * CBA/J)
increased osteoclast cell number J:233240
Tg(Tnfsf13b)1Fma/0
(involves: C57BL/6 * DBA/2J)
abnormal B cell morphology J:58798
abnormal B cell physiology J:58798
abnormal spleen follicular dendritic cell network J:58798
abnormal spleen morphology J:58798
abnormal spleen periarteriolar lymphoid sheath morphology J:58798
abnormal T cell number J:58798
abnormal T cell physiology J:58798
abnormal T cell subpopulation ratio J:58798
enlarged lymph nodes J:58798
enlarged Peyer's patches J:58798
enlarged spleen J:58798
increased anti-double stranded DNA antibody level J:58798
increased anti-single stranded DNA antibody level J:58798
increased autoantibody level J:58798
increased B cell number J:58798
increased IgG level J:58798
increased IgM level J:58798
increased immunoglobulin level J:58798
increased lymphocyte cell number J:58798
increased marginal zone B cell number J:58798
increased mature B cell number J:58798
increased plasma cell number J:58798
increased spleen B cell follicle size J:58798
increased spleen germinal center size J:58798
increased T cell number J:58798
Tg(Tnfsf13b)1Fma/0
(B6.Cg-Tg(Tnfsf13b)1Fma)
abnormal B cell differentiation J:73711
abnormal B-1 B cell morphology J:114782
abnormal spleen germinal center morphology J:114782
abnormal spleen marginal zone morphology J:114782
increased autoantibody level J:114782
increased B cell number J:114782
increased B-1a cell number J:114782
increased B-1b cell number J:114782
increased IgA level J:114782
increased plasma cell number J:114782
kidney inflammation J:73711
salivary gland inflammation J:73711
Tg(Tnfsf13b)1Fma/0
(involves: C57BL/6J * DBA/2J)
abnormal B cell differentiation J:115788
abnormal B-1 B cell morphology J:115788
Tg(Tnfsf13b)1Fma/?
(B6.Cg-Tg(Tnfsf13b)1Fma)
abnormal B cell activation J:113556
abnormal marginal zone B cell physiology J:113556
abnormal spleen marginal zone morphology J:113556
glomerulonephritis J:113556
increased anti-double stranded DNA antibody level J:113556
increased B cell number J:113556
increased marginal zone B cell number J:113556
increased transitional stage B cell number J:113556
Tg(Tnfsf13b)1Fma/?
Tnfrsf13btm1Rjb/Tnfrsf13btm1Rjb

(B6.Cg-Tnfrsf13btm1Rjb Tg(Tnfsf13b)1Fma)
abnormal class switch recombination J:113556
Tg(Tnfsf13b)1Fma/?
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass

(B6.Cg-Tnfrsf13ctm1Mass Tg(Tnfsf13b)1Fma)
abnormal class switch recombination J:113556
Tg(Tnfsf13b)1Fma/0
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf

(involves: 129P2/OlaHsd * C57BL/6 * DBA/2J)
abnormal spleen germinal center morphology J:114782
abnormal spleen marginal zone morphology J:114782
increased B cell number J:114782
increased IgA level J:114782
increased plasma cell number J:114782
Tg(Tnfsf13b)1Fma/Tg(Tnfsf13b)1Fma
(involves: C57BL/6 * DBA/2)
abnormal immunoglobulin level J:178227
increased B cell number J:178227
increased IgA level J:178227
increased IgM level J:178227
increased immunoglobulin level J:178227
increased marginal zone B cell number J:178227
increased transitional stage T2 B cell number J:178227
kidney inflammation J:178227
Tg(Tox)1Kay/?
Toxtm1.1Kay/Toxtm1.1Kay

(involves: 129S6/SvEvTac * C57BL/6)
abnormal T cell number J:131287
Tg(Trp53)1Srn/0
(involves: C57BL/6 * CBA)
increased thymocyte apoptosis J:80311
Tg(Trp53)1Srn/0
Trp53tm1Tyj/Trp53tm1Tyj

(involves: 129S2/SvPas * C57BL/6 * CBA)
decreased thymocyte apoptosis J:80311
Tg(Trp53)bSrn/0
(involves: C57BL/6 * CBA)
increased thymocyte apoptosis J:80311
Tg(Trp53A135V)L3Ber/0
(involves: C57BL/6 * CD-1)
decreased spleen weight J:73757
Tg(Ttr-IGF1)1Sykr/0
(FVB/N-Tg(Ttr-IGF1)1Sykr)
increased spleen weight J:157350
Tg(Tyr-NRAS*Q61K)1Bee/?
(involves: BALB/c * C57BL/6J * DBA/2)
skin inflammation J:98545
Tg(Tyr-NRAS*Q61K)1Bee/?
(involves: C57BL/6J * DBA/2)
skin inflammation J:98545
Tg(UBC-scFv)2Nemz/0
(involves: C57BL/6 * DBA/2)
abnormal B cell differentiation J:96759
abnormal B cell morphology J:96759
abnormal B cell receptor editing J:96759
abnormal B-1 B cell morphology J:96759
abnormal immune tolerance J:96759
abnormal immunoglobulin level J:96759
abnormal mature B cell morphology J:96759
decreased mature B cell number J:96759
decreased splenocyte number J:96759
spleen hypoplasia J:96759
Tg(Umod*C147W)958Lura/0
(involves: FVB)
kidney inflammation J:161532
Tg(Vav1-Asxl1*Y588X)#Fcy/0
(C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy)
abnormal neutrophil morphology J:257690
abnormal spleen morphology J:257690
decreased leukocyte cell number J:257690
decreased lymphocyte cell number J:257690
enlarged spleen J:257690
hepatosplenomegaly J:257690
increased leukocyte cell number J:257690
increased monocyte cell number J:257690
increased neutrophil cell number J:257690
Tg(VAV1-cre)1Graf/?
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/?
Trip11tm1.1Psmi/Trip11tm1.2Psmi

(involves: 129/Sv * C57BL/6)
immune system phenotype J:253969
Tg(Vav1-ERG)#Jpim/0
(involves: C57BL/6)
abnormal thymus morphology J:174808
enlarged spleen J:174808
enlarged thymus J:174808
Tg(Vav1-JAK2*V617F)AZjz/0
(involves: C57BL/6 * DBA/2)
enlarged spleen J:135993
increased granulocyte number J:135993
increased leukocyte cell number J:135993
increased spleen weight J:135993
spleen fibrosis J:135993
Tg(Vav1-Lin28b)C3Apla/0
(involves: C57BL/6)
abnormal cytokine level J:189197
abnormal inflammatory response J:189197
abnormal T cell differentiation J:189197
abnormal thymus cell ratio J:189197
abnormal thymus cortex morphology J:189197
abnormal thymus corticomedullary boundary morphology J:189197
decreased CD4-positive, alpha-beta T cell number J:189197
decreased CD8-positive, alpha-beta T cell number J:189197
decreased double-positive T cell number J:189197
decreased leukocyte cell number J:189197
decreased lymphocyte cell number J:189197
decreased thymocyte number J:189197
enlarged lymph nodes J:189197
enlarged spleen J:189197
enlarged thymus medulla J:189197
increased CD8-positive, alpha-beta T cell number J:189197
increased effector memory CD4-positive, alpha-beta T cell number J:189197
increased effector memory CD8-positive, alpha-beta T cell number J:189197
increased eosinophil cell number J:189197
increased IgG level J:189197
increased neutrophil cell number J:189197
increased T cell proliferation J:189197
Tg(Vav1-NUP98/HOXD13)C1Apla/0
(FVB/N-Tg(Vav1-NUP98/HOXD13)C1Apla)
abnormal neutrophil morphology J:107446
decreased leukocyte cell number J:107446
Tg(Vav1-NUP98/HOXD13)G2Apla/0
(C57BL/6-Tg(Vav1-NUP98/HOXD13)G2Apla)
abnormal neutrophil morphology J:107446
decreased leukocyte cell number J:107446
decreased lymphocyte cell number J:107446
decreased neutrophil cell number J:107446
Tg(Vav1-STAT5B*N642H)726Biat/0
(C57BL/6NCrl-Tg(Vav1-STAT5B*N642H)726Biat)
abnormal effector T cell number J:257519
abnormal lymph node morphology J:257519
abnormal spleen morphology J:257519
enlarged spleen J:257519
increased CD4-positive, alpha-beta T cell number J:257519
increased CD8-positive, alpha-beta T cell number J:257519
increased leukocyte cell number J:257519
increased T cell proliferation J:257519
Tg(Vav-BCL2)69Jad/0
(involves: C57BL/6J)
abnormal class switch recombination J:88565
abnormal lymphocyte cell number J:88565
abnormal somatic hypermutation frequency J:88565
abnormal spleen germinal center morphology J:88565
enlarged lymph nodes J:88565
enlarged spleen J:88565
glomerulonephritis J:88565
increased B cell number J:88565
increased CD4-positive, alpha-beta T cell number J:88565
increased CD8-positive, alpha-beta T cell number J:88565
increased spleen germinal center number J:88565
increased spleen germinal center size J:88565
increased T cell number J:88565
Tg(Vil1-cre)997Gum/?
Tlr4lps-del/Tlr4lps-del
Tlr5tm1.1Gewr/Tlr5tm1.1Gewr

(involves: C57BL/6J * C57BL/6NTac * C57BL/10ScN * SJL)
large intestinal inflammation J:229155
Tg(Vil1-cre)997Gum/?
Tlr5tm1.1Gewr/Tlr5tm1.1Gewr

(involves: C57BL/6J * C57BL/6NTac * SJL/J)
enlarged spleen J:229155
increased interleukin-1 beta secretion J:229155
increased susceptibility to colitis induced morbidity/mortality J:229155
large intestinal inflammation J:229155
Tg(Vil1-cre)997Gum/0
Tnfrsf11atm1.1Irw/Tnfrsf11atm1.1Irw

(involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac * SJL)
abnormal Peyer's patch epithelium morphology J:219915, J:226603
abnormal Peyer's patch follicle morphology J:226603
abnormal Peyer's patch germinal center morphology J:226603
abnormal Peyer's patch morphology J:226603
abnormal Peyer's patch T cell area morphology J:226603
decreased IgA level J:226603
decreased plasma cell number J:226603
Tg(Vil-SLC3A2)HEMerl/0
(involves: FVB/N)
colitis J:173946
increased circulating tumor necrosis factor level J:173946
increased susceptibility to induced colitis J:173946
Tg(VIM-Tag)3Pau/0
(involves: C57BL/6 * SJL/J)
enlarged thymus J:91542
increased double-negative T cell number J:91542
thymus hyperplasia J:91542
Tg(VIM-Tag)3Pau/0
(either: (involves: C57BL/6 * CBA * SJL/J) or (involves: C57BL/6 * SJL/J))
glomerulonephritis J:92226
Tgm3Btlr/Tgm3Btlr
(C57BL/6J-Tgm3Btlr)
decreased B cell number J:265197
decreased IgE level J:265197
increased susceptibility to induced colitis J:265197
Tgm4Btlr/Tgm4Btlr
(C57BL/6J-Tgm4Btlr)
decreased B cell number J:272522
decreased B-2 B cell number J:272522
increased alpha-beta T cell number J:272522
increased B-1a cell number J:272522
increased CD4-positive, alpha-beta T cell number J:272522
increased CD8-positive, alpha-beta T cell number J:272522
increased central memory CD4-positive, alpha-beta T cell number J:272522
increased IgE level J:272522
increased macrophage cell number J:272522
TgM5Btlr/TgM5Btlr
(C57BL/6J-TgM5Btlr)
increased central memory CD4-positive, alpha-beta T cell number J:272523
Tgm6Btlr/Tgm6Btlr
(C57BL/6J-Tgm6Btlr)
increased alpha-beta T cell number J:272525
tga/tga
(C57BL/6J-tga)
thymus hypoplasia J:94456
Tgfatm1Ard/Tgfatm1Ard
(involves: 129P2/OlaHsd * C57BL/6)
increased incidence of corneal inflammation J:4606
Tgfatm1Unc/Tgfatm1Unc
(involves: 129P2/OlaHsd * C57BL/6J)
immune system phenotype J:4605
Tgfawa1/Tgfawa1
(Not Specified)
conjunctivitis J:13115
keratoconjunctivitis J:13115
Tgfb1tm1(Tgfb3)Kul/Tgfb1tm1(Tgfb3)Kul
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal T cell morphology J:204892
immune system phenotype J:204892
increased monocyte cell number J:204892
increased regulatory T cell number J:204892
Tgfb1tm1Doe/Tgfb1tm1Doe
(involves: 129S2/SvPas * CF-1)
abnormal inflammatory response J:2892
abnormal Peyer's patch germinal center morphology J:2892
brain inflammation J:2892
conjunctivitis J:2892
decreased Peyer's patch number J:2892
diaphragmitis J:2892
enlarged lymph nodes J:2892
eye inflammation J:2892
heart inflammation J:2892
increased leukocyte cell number J:2892
lacrimal gland inflammation J:2892
liver inflammation J:2892
lung inflammation J:2892
myositis J:2892
pancreas inflammation J:2892
salivary gland inflammation J:2892
skin inflammation J:2892
small spleen J:2892
stomach inflammation J:2892
Tgfb1tm1Doe/Tgfb1tm1Doe
(involves: 129S2/SvPas * BALB/c * CF-1)
heart inflammation J:69346
increased interferon-gamma secretion J:69346
liver inflammation J:69346
lung inflammation J:69346
Tgfb1tm1Doe/Tgfb1tm1Doe
(C.129S2-Tgfb1tm1Doe)
decreased CD4-positive, alpha-beta T cell number J:69346
heart inflammation J:69346
increased CD4-positive, alpha-beta T cell number J:69346
increased interferon-gamma secretion J:69346
increased T-helper 1 cell number J:69346
liver inflammation J:69346
Tgfb1tm1Doe/Tgfb1tm2.1Doe
Tg(Lck-cre)548Jxm/?

(involves: 129S2/SvPas * 129S6/SvEvTac * Black Swiss * BALB/c * C57BL/6 * CBA)
lung inflammation J:150024
salivary gland inflammation J:150024
Tgfb1tm1Jmu/Tgfb1tm1Jmu
(involves: 129S6/SvEvTac * C57BL/6)
abnormal immune system physiology J:120085
absent Langerhans cell J:120085
heart inflammation J:120085
liver inflammation J:120085
lung inflammation J:120085
pancreas inflammation J:120085
stomach inflammation J:120085
Tgfb1tm1Jmu/Tgfb1tm1Jmu
(involves: 129S6/SvEvTac * C57BL/6 * Swiss Webster)
abnormal immune system physiology J:120085
absent Langerhans cell J:120085
Tgfb1tm1N/Tgfb1tm1N
(involves: 129S/SvEv)
abnormal immune system physiology J:120085
absent Langerhans cell J:120085
atrial endocarditis J:50848
increased inflammatory response J:50848
interstitial pneumonia J:50848
lymph node inflammation J:50848
myocarditis J:50848
pancreas inflammation J:50848
pericarditis J:50848
phlebitis J:50848
salivary gland inflammation J:50848
Tgfb1tm1Rif/Tgfb1tm1Rif
(Not Specified)
abnormal immune system physiology J:141786
Tgfb1tm1Rif/Tgfb1tm1Rif
(either: (involves: 129) or (involves: 129S/SvEv * C57BL/6))
absent Langerhans cell J:142353
cecum inflammation J:142353
heart inflammation J:142353
increased inflammatory response J:142353
large intestinal inflammation J:142353
lung inflammation J:142353
proctitis J:142353
small intestinal inflammation J:142353
stomach inflammation J:142353
Tgfb1tm2Flv/B9d2/Tgfb1tm1Flv
Tg(CD207-cre)1Dhka/?

(involves: 129S6/SvEvTac * C57BL/6J * SJL/J)
decreased Langerhans cell number J:126147
Tgfb1tm3.1Flv/Tgfb1tm3.1Flv
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2 * NOD)
increased regulatory T cell number J:196160
increased T-helper 1 cell number J:196160
Tgfb1tm3.1Flv/Tgfb1tm3.1Flv
Tg(Cd4-cre)1Cwi/0
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(involves: 129 * C57BL/6 * DBA/2 * NOD * SJL)
increased regulatory T cell number J:196160
increased susceptibility to autoimmune diabetes J:196160
increased T-helper 1 cell number J:196160
Tgfb2tm1Doe/Tgfb2tm1Doe
(involves: 129P2/OlaHsd * Black Swiss)
abnormal macrophage physiology J:73681
Tgfb3tm1.1(KOMP)Vlcg/Tgfb3+
(C57BL/6N-Tgfb3tm1.1(KOMP)Vlcg/Tcp)
enlarged lymph nodes J:211773
Tgfbitm1Zhao/Tgfbitm1Zhao
(involves: 129 * C57BL/6J)
enlarged spleen J:143036
increased B cell number J:143036
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Cd4-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
abnormal T cell activation J:148747
autoimmune response J:148747
liver inflammation J:148747
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2 * NOD)
increased inflammatory response J:196160
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Cd4-cre)1Cwi/0
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(involves: 129 * C57BL/6 * DBA/2 * NOD * SJL)
abnormal abdominal lymph node morphology J:196160
abnormal immune serum protein physiology J:196160
abnormal immune system morphology J:196160
abnormal immune system organ morphology J:196160
abnormal immune system physiology J:196160
abnormal interleukin secretion J:196160
abnormal spleen morphology J:196160
decreased interleukin-9 secretion J:196160
decreased interleukin-17 secretion J:196160
decreased regulatory T cell number J:196160
immune system phenotype J:196160
increased interferon-gamma secretion J:196160
increased interleukin-2 secretion J:196160
increased interleukin-21 secretion J:196160
increased regulatory T cell number J:196160
increased susceptibility to autoimmune diabetes J:196160
pancreas inflammation J:196160
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(CD207-cre)1Dhka/?

(involves: 129S6/SvEvTac * C57BL/6J * SJL/J)
decreased Langerhans cell number J:126147
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Foxp3-EGFP/cre)1cJbs/0
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(involves: 129S6/SvEvTac * C57BL/6 * NOD * SJL)
immune system phenotype J:196160
increased regulatory T cell number J:196160
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tnfrsf4tm2(cre)Nik/Tnfrsf4+
Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0

(involves: 129 * C57BL/6 * NOD * SJL)
immune system phenotype J:196160
increased susceptibility to autoimmune diabetes J:196160
Tgfbr2tm1Karl/Tgfbr2tm1Karl
H2az2Tg(Wnt1-cre)11Rth/H2az2+

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
small thymus J:96359
Tgfbr2tm1Karl/Tgfbr2tm1Karl
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA)
eye inflammation J:77844
increased inflammatory response J:77844
liver inflammation J:77844
pancreas inflammation J:77844
small thymus J:77844
stomach inflammation J:77844
Tgfbr3tm1Stv/Tgfbr3tm1Stv
(involves: 129/Sv * C57BL/6)
abnormal spleen morphology J:83727
decreased spleen white pulp amount J:83727
Tgif1tm1.1Caw/Tgif1tm1.1Caw
(B6.129S-Tgif1tm1.1Caw)
abnormal cytokine level J:198238
increased susceptibility to otitis media J:198238
Tgm2tm1.1Rmgr/Tgm2tm1.1Rmgr
(involves: 129S1/SvImJ * C57BL/6)
abnormal T cell physiology J:95130
Tgm2tm1Gml/Tgm2tm1Gml
(involves: C57BL/6)
decreased susceptibility to endotoxin shock J:131975
immune system phenotype J:131975
increased macrophage cell number J:131975
Tgm2tm1Gml/Tgm2tm1Gml
(involves: C57BL/6 * DBA/1LacJ)
abnormal thymus morphology J:132254
impaired macrophage phagocytosis J:132254
Tgm6em1Bge/Tgm6em1Bge
(C57BL/6N-Tgm6em1Bge)
increased susceptibility to bacterial infection J:268324
TgTn(pb-CAG-Gm614)#Cya/0
(involves: C57BL/6)
decreased B cell apoptosis J:307345
immune system phenotype J:307345
increased susceptibility to systemic lupus erythematosus J:307345
TgTn(pb-CAG-Gm40600)#Rew/0
(C57BL/6-TgTn(pb-CAG-Gm40600)#Rew)
abnormal plasmablast number J:311878
decreased B cell number J:311878
decreased IgA level J:311878
decreased IgE level J:311878
decreased IgG1 level J:311878
decreased IgG2b level J:311878
decreased IgG2c level J:311878
decreased IgG3 level J:311878
decreased IgG level J:311878
decreased IgM level J:311878
decreased plasma cell number J:311878
increased B cell number J:311878
increased IgA level J:311878
increased IgE level J:311878
increased IgG1 level J:311878
increased IgG2b level J:311878
increased IgG2c level J:311878
increased IgG3 level J:311878
increased IgG level J:311878
increased IgM level J:311878
increased plasma cell number J:311878
Thbdtm1.1Hlwu/Thbdtm1.1Hlwu
Lyz2tm1(cre)Ifo/Lyz2+

(B6.129-Thbdtm1.1Hlwu Lyz2tm1(cre)Ifo)
decreased circulating interleukin-6 level J:188879
decreased circulating tumor necrosis factor level J:188879
decreased susceptibility to bacterial infection J:188879
decreased susceptibility to bacterial infection induced morbidity/mortality J:188879
decreased tumor necrosis factor secretion J:188879
Thbdtm1Wlr/Thbdtm1Wlr
(B6.129S2-Thbdtm1Wlr)
abnormal spleen morphology J:111502
decreased circulating tumor necrosis factor level J:111502
increased circulating interleukin-1 beta level J:111502
increased circulating interleukin-6 level J:111502
increased susceptibility to endotoxin shock J:111502
Thbdtm1Wlr/Thbdtm2Rdr
(involves: 129S2/SvPas * C57BL/6)
abnormal spleen morphology J:111502, J:47676
Thbdtm2.1Emc/Thbdtm2.1Emc
(involves: 129/Sv * BALB/c * C57BL/6)
abnormal leukocyte adhesion J:118000
abnormal leukocyte physiology J:118000
increased circulating interleukin-1 beta level J:118000
increased circulating tumor necrosis factor level J:118000
increased susceptibility to endotoxin shock J:118000
Thbdtm2Emc/Thbdtm2Emc
(either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6))
abnormal leukocyte physiology J:118000
Thbs1tm1Hyn/Thbs1tm1Hyn
(either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * C57BL/6))
increased eosinophil cell number J:46182
increased leukocyte cell number J:46182
increased lymphocyte cell number J:46182
increased monocyte cell number J:46182
increased neutrophil cell number J:46182
lung inflammation J:46182, J:48446
pancreas inflammation J:48446
Thbs1tm1Hyn/Thbs1tm1Hyn
(involves: 129S2/SvPas * C57BL/6)
decreased interferon-gamma secretion J:153126
decreased regulatory T cell number J:153126
increased anti-single stranded DNA antibody level J:153126
increased CD4-positive, alpha-beta T cell number J:153126
increased interleukin-17 secretion J:153126
lacrimal gland inflammation J:153126
Thbs1tm1Hyn/Thbs1tm1Hyn
Thbs2tm1Bst/Thbs2tm1Bst

(involves: 129T2/SvEms * 129X1/SvJ)
impaired macrophage chemotaxis J:78876
lung inflammation J:78876
Thbs2em1(IMPC)Mbp/Thbs2em1(IMPC)Mbp
(C57BL/6NCrl-Thbs2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
ThcrBALB/cJ/?
(involves: BALB/cJ * C57BL/10J * DBA/2J)
decreased interferon-gamma secretion J:86188
increased interleukin-4 secretion J:86188
ThcrC57BL/10Sn/?
(involves: BALB/cJ * C57BL/10J * DBA/2J)
decreased interleukin-4 secretion J:86188
increased interferon-gamma secretion J:86188
Themis2tm1d(KOMP)Wtsi/Themis2tm1d(KOMP)Wtsi
(involves: 129S4/SvJae * C57BL/6 * C57BL/6N * SJL)
immune system phenotype J:232061
Themis5AT161/Themis5AT161
(involves: C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:151076
decreased CD8-positive, alpha-beta T cell number J:151076
decreased regulatory T cell number J:151076
decreased single-positive T cell number J:151076
Themism1Btlr/Themism1Btlr
(C57BL/6J-Themism1Btlr)
abnormal lymphocyte morphology J:211400
decreased B-1a cell number J:211400
decreased CD4-positive, alpha-beta T cell number J:211400
decreased CD8-positive, alpha-beta T cell number J:211400
immune system phenotype J:211400
impaired humoral immune response J:211400
Themism2Btlr/Themism2Btlr
(C57BL/6J-Themism2Btlr)
decreased CD4-positive, alpha-beta T cell number J:236691
decreased T cell number J:236691
increased CD8-positive, alpha-beta T cell number J:236691
increased effector memory CD4-positive, alpha-beta T cell number J:236691
Themism3Btlr/Themism3Btlr
(C57BL/6J-Themism3Btlr)
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:254834
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254834
decreased CD8-positive, alpha-beta memory T cell number J:254834
decreased CD8-positive, naive alpha-beta T cell number J:254834
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254834
increased CD8-positive, alpha-beta memory T cell number J:254834
increased central memory CD4-positive, alpha-beta T cell number J:254834
increased central memory CD8 positive, alpha-beta T cell number J:254834
increased effector memory CD4-positive, alpha-beta T cell number J:254834
ThemisM4Btlr/ThemisM4Btlr
(C57BL/6J-ThemisM4Btlr)
decreased CD4-positive, alpha-beta T cell number J:272849
Themism5Btlr/Themism5Btlr
(C57BL/6J-Themism5Btlr)
abnormal CD4-positive T cell differentiation J:274716
abnormal CD8-positive, alpha-beta T cell differentiation J:274716
abnormal T cell differentiation J:274716
decreased alpha-beta T cell number J:274716
decreased CD4-positive, alpha-beta T cell number J:274716
decreased CD8-positive, alpha-beta T cell number J:274716
decreased CD8-positive, naive alpha-beta T cell number J:274716
increased CD8-positive, alpha-beta memory T cell number J:274716
increased central memory CD4-positive, alpha-beta T cell number J:274716
increased central memory CD8 positive, alpha-beta T cell number J:274716
increased effector memory CD4-positive, alpha-beta T cell number J:274716
increased effector memory CD8-positive, alpha-beta T cell number J:274716
increased NK T cell number J:274716
ThemisSpotr/Themis+
(C57BL/6-ThemisSpotr)
decreased CD4-positive, alpha-beta T cell number J:152601
decreased CD8-positive, alpha-beta T cell number J:152601
ThemisSpotr/ThemisSpotr
(C57BL/6-ThemisSpotr)
abnormal T cell differentiation J:152601
decreased CD4-positive, alpha-beta T cell number J:152601
decreased CD8-positive, alpha-beta T cell number J:152601
small thymus medulla J:152601
Themistm1.1Hko/Themis+
(Not Specified)
decreased CD4-positive, alpha-beta T cell number J:152601
decreased CD8-positive, alpha-beta T cell number J:152601
Themistm1.1Hko/Themistm1.1Hko
(Not Specified)
decreased CD4-positive, alpha-beta T cell number J:152601
decreased CD8-positive, alpha-beta T cell number J:152601
decreased single-positive T cell number J:152601
Themistm1Gasc/Themistm1Gasc
(B6.129S-Themistm1Gasc)
abnormal memory T cell morphology J:151074
abnormal positive T cell selection J:151074
abnormal regulatory T cell morphology J:151074
abnormal thymus medulla morphology J:151074
decreased CD4-positive, alpha-beta T cell number J:151074
decreased CD8-positive, alpha-beta T cell number J:151074
decreased T cell proliferation J:151074
decreased thymocyte number J:151074
increased double-positive T cell number J:151074
Themistm1Hasu/Themis+
(involves: C57BL/6 * CBA)
decreased CD4-positive, alpha-beta T cell number J:153235
decreased CD8-positive, alpha-beta T cell number J:153235
Themistm1Hasu/Themistm1Hasu
(involves: C57BL/6 * CBA)
abnormal T cell differentiation J:153235
decreased CD4-positive, alpha-beta T cell number J:153235
decreased CD8-positive, alpha-beta T cell number J:153235
decreased splenocyte number J:153235
decreased thymocyte number J:153235
increased memory T cell number J:153235
increased T cell proliferation J:153235
Themistm1Lov/Themistm1Lov
(involves: 129)
abnormal negative T cell selection J:151075
abnormal T cell differentiation J:151075
decreased CD4-positive, alpha-beta T cell number J:151075
decreased CD8-positive, alpha-beta T cell number J:151075
decreased regulatory T cell number J:151075
decreased single-positive T cell number J:151075
increased memory T cell number J:151075
thnh/thnh
(NOD.Cg-H2b thnh/J)
folliculitis J:142872
Thnsl2em1(IMPC)Tcp/Thnsl2em1(IMPC)Tcp
(C57BL/6NCrl-Thnsl2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Thoc6em5(IMPC)Tcp/Thoc6+
(C57BL/6NCrl-Thoc6em5(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Thop1em1(IMPC)Mbp/Thop1em1(IMPC)Mbp
(C57BL/6NCrl-Thop1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
decreased leukocyte cell number J:211773
enlarged spleen J:211773
Thop1Gt(CSG163)Byg/Thop1Gt(CSG163)Byg
(B6.129P2-Thop1Gt(CSG163)Byg)
decreased lymphocyte cell number J:290567
decreased susceptibility to infection J:290567
decreased susceptibility to infection induced morbidity/mortality J:290567
increased granulocyte number J:290567
increased monocyte cell number J:290567
increased susceptibility to experimental autoimmune encephalomyelitis J:290567
Thpotm1Mwm/Thpotm1Mwm
(involves: 129S2/SvPas * C57BL/6)
immune system phenotype J:83262
Thratm1Ffla/Thra+
Tg(Sycp1-cre)4Min/?

(involves: 129/Sv * C57BL/6 * DBA/2)
decreased spleen weight J:125353
Thratm1Syc/Thra+
(involves: 129S6/SvEvTac * C57BL/6J * NIH Black Swiss)
abnormal osteoclast physiology J:217018
decreased osteoclast cell number J:217018
Thratm2Jas/Thratm2Jas
(involves: 129)
abnormal osteoclast physiology J:120899
decreased osteoclast cell number J:120899
Thratm2Ven/Thratm2Ven
(involves: 129P2/OlaHsd * BALB/c)
abnormal osteoclast physiology J:72959
Thrbtm1Olc/Thrbtm1Olc
(involves: 129)
abnormal osteoclast physiology J:120899
increased osteoclast cell number J:120899
Thyct1C57BL/6J/Thyct1C57BL/6J
Thyct2C57BL/6J/Thyct2C57BL/6J

(involves: C57BL/6J * DBA/2J)
thymus hyperplasia J:85261
Thyct1DBA/2J/Thyct1DBA/2J
Thyct2DBA/2J/Thyct2DBA/2J

(involves: C57BL/6J * DBA/2J)
thymus hypoplasia J:85261
Thypr1DBA/2J/?
(involves: C57BL/6J * DBA/2J)
increased T cell proliferation J:76931
Thypr2DBA/2J/?
(involves: C57BL/6J * DBA/2J)
increased T cell proliferation J:76931
Tia1tm1Andp/Tia1tm1Andp
(C.129S2-Tia1tm1Andp)
abnormal macrophage physiology J:88770
immune system phenotype J:88770
increased susceptibility to endotoxin shock J:88770
Tia1tm1Andp/Tia1tm1Andp
(B6.Cg-Tia1tm1Andp)
arthritis J:88443
Tia1tm1Andp/Tia1tm1Andp
Zfp36tm1Pjb/Zfp36tm1Pjb

(B6.Cg-Tia1tm1Andp Zfp36tm1Pjb)
abnormal macrophage physiology J:88443
arthritis J:88443
increased neutrophil cell number J:88443
Ticam1Lps2/Ticam1Lps2
(involves: C57BL/6)
abnormal cytokine secretion J:110201
abnormal macrophage physiology J:84896
decreased circulating tumor necrosis factor level J:86521
decreased macrophage apoptosis J:84896, J:92674
decreased macrophage cytokine production J:84896
decreased macrophage nitric oxide production J:84896
decreased susceptibility to bacterial infection J:86521, J:92674
decreased susceptibility to endotoxin shock J:84896
decreased tumor necrosis factor secretion J:84896
increased susceptibility to Herpesvirales infection J:84896
Ticam1Lps2/Ticam1Lps2
(C57BL/6J-Ticam1Lps2)
abnormal circulating tumor necrosis factor level J:138963
abnormal cytokine secretion J:167340
decreased interleukin-6 secretion J:167340
decreased susceptibility to induced colitis J:167340
immune system phenotype J:131353
Ticam1Lps2/Ticam1Lps2
(C57BL/6J-Ticam1Lps2/J)
abnormal chemokine level J:288471
decreased CD8-positive, alpha-beta T cell number J:288471
decreased Ly6C low monocyte number J:288471
increased interferon-beta secretion J:288471
increased Ly6C high monocyte number J:288471
increased macrophage cell number J:288471
increased neutrophil cell number J:288471
increased plasmacytoid dendritic cell number J:288471
increased susceptibility to Coronaviridae infection J:288471
increased susceptibility to Coronaviridae infection induced morbidity/mortality J:288471
Ticam1Lps2/Ticam1Lps2
Myd88tm1Aki/Myd88tm1Aki

(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:84896
decreased tumor necrosis factor secretion J:84896
Ticam1M2Btlr/Ticam1+
(C57BL/6J-Ticam1M2Btlr)
abnormal cytokine secretion J:234240
abnormal macrophage physiology J:234240
decreased macrophage cytokine production J:234240
decreased tumor necrosis factor secretion J:234240
Ticam1M2Btlr/Ticam1M2Btlr
(C57BL/6J-Ticam1M2Btlr)
abnormal cytokine secretion J:234240
abnormal macrophage physiology J:234240
decreased macrophage cytokine production J:234240
decreased tumor necrosis factor secretion J:234240
Ticam1M3Btlr/Ticam1+
(C57BL/6J-Ticam1M3Btlr)
decreased tumor necrosis factor secretion J:255300
Ticam1M3Btlr/Ticam1M3Btlr
(C57BL/6J-Ticam1M3Btlr)
decreased tumor necrosis factor secretion J:255300
Ticam1tm1Aki/Ticam1tm1Aki
(involves: 129P2/OlaHsd)
abnormal B cell activation J:174941
abnormal B cell physiology J:84679
abnormal cytokine level J:174941
abnormal cytokine secretion J:84679
abnormal dendritic cell physiology J:174941
abnormal interleukin level J:137522
abnormal macrophage physiology J:174941, J:84679
abnormal microglial cell physiology J:185198
abnormal NK cell physiology J:174941
abnormal NK T cell physiology J:174941
decreased circulating interleukin-6 level J:145306
decreased splenocyte proliferation J:84679
decreased susceptibility to endotoxin shock J:84679
decreased susceptibility to Orthomyxoviridae infection J:145306
impaired macrophage phagocytosis J:185198
Ticam1tm1Aki/Ticam1tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine level J:169158
abnormal susceptibility to Poxviridae infection J:162716
decreased CD8-positive, alpha-beta T cell number J:130954
decreased circulating interferon-gamma level J:130954
decreased circulating interleukin-6 level J:130954
decreased circulating interleukin-12b level J:130954
decreased IgG2a level J:130954
decreased IgG level J:130954
decreased interferon-beta secretion J:130954
decreased interleukin-12b secretion J:130954
decreased susceptibility to type I hypersensitivity reaction J:161445
immune system phenotype J:132662
increased susceptibility to Picornaviridae infection J:169158
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:169158
myocarditis J:169158
Ticam1tm1Aki/Ticam1tm1Aki
(B6.129P2-Ticam1tm1Aki)
abnormal cytokine level J:144301
abnormal response to infection J:144301
decreased circulating tumor necrosis factor level J:144301
decreased macrophage cytokine production J:144301
impaired neutrophil recruitment J:144301
increased susceptibility to bacterial infection J:144301
Ticam1tm1Tsse/Ticam1tm1Tsse
(B6.129-Ticam1tm1Tsse)
impaired natural killer cell mediated cytotoxicity J:118750
Ticam1tm1Tsse/Ticam1tm1Tsse
Tg(PVR)1Kkst/0

(involves: 129 * C57BL/6 * ICR)
abnormal interferon-alpha secretion J:179625
increased susceptibility to Picornaviridae infection J:179625
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:179625
Ticam2M1Btlr/Ticam2+
(C57BL/6J-Ticam2M1Btlr)
decreased tumor necrosis factor secretion J:215010
Ticam2M1Btlr/Ticam2M1Btlr
(C57BL/6J-Ticam2M1Btlr)
decreased tumor necrosis factor secretion J:215010
Ticam2M2Btlr/Ticam2+
(C57BL/6J-Ticam2M2Btlr)
decreased interleukin-1 beta secretion J:254908
Ticam2M2Btlr/Ticam2M2Btlr
(C57BL/6J-Ticam2M2Btlr)
decreased interleukin-1 beta secretion J:254908
Ticam2M3Btlr/Ticam2+
(C57BL/6J-Ticam2M3Btlr)
decreased tumor necrosis factor secretion J:254912
Ticam2M3Btlr/Ticam2M3Btlr
(C57BL/6J-Ticam2M3Btlr)
decreased tumor necrosis factor secretion J:254912
Ticam2tm1Aki/Ticam2tm1Aki
(involves: C57BL/6)
abnormal immune system physiology J:86256
decreased interleukin-6 secretion J:86256
increased susceptibility to Coronaviridae infection J:270045
Ticam2tm1Btlr/Ticam2tm1Btlr
(C57BL/6J-Ticam2tm1Btlr)
abnormal interferon secretion J:133619
decreased tumor necrosis factor secretion J:133619
Tie1tm1.1Scba/Tie1tm1.1Scba
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
abnormal lymphangiogenesis J:158668
abnormal lymphatic vessel morphology J:158668
lymphatic vessel hyperplasia J:158668
Tie1tm1Geno/Tie1tm1Geno
(involves: ICR)
abnormal lymphangiogenesis J:159507
Tie1tm1Jpa/Tie1tm1Jpa
(involves: 129S1/Sv * 129X1/SvJ * ICR)
abnormal lymphangiogenesis J:159507
Tie1tm1Scba/Tie1tm1Scba
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal lymph circulation J:158668
abnormal lymphangiogenesis J:158668
abnormal lymphatic vessel morphology J:158668
lymphatic vessel hyperplasia J:158668
Tifabem1(IMPC)J/Tifabem1(IMPC)J
(C57BL/6NJ-Tifabem1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Tifabtm1.1Dsta/Tifab+
(involves: 129 * C57BL/6 * C57BL/6J)
enlarged spleen J:229024
Tifabtm1.1Dsta/Tifabtm1.1Dsta
(involves: 129 * C57BL/6 * C57BL/6J)
abnormal neutrophil morphology J:229024
decreased leukocyte cell number J:229024
decreased lymphocyte cell number J:229024
decreased monocyte cell number J:229024
decreased neutrophil cell number J:229024
enlarged spleen J:229024
TigarGt(EUCE0047g05)Hmgu/TigarGt(EUCE0047g05)Hmgu
(involves: 129P2/OlaHsd)
increased susceptibility to induced colitis J:198650
Tigartm1.1Khv/Tigartm1.1Khv
Tg(CMV-cre)1Cgn/0

(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * SJL)
increased susceptibility to induced colitis J:198650
Tigittm1Sdl/Tigittm1Sdl
(involves: C57BL/6)
abnormal professional antigen presenting cell physiology J:168902
decreased interleukin-10 secretion J:168902
immune system phenotype J:209990
increased susceptibility to experimental autoimmune encephalomyelitis J:168902
increased T cell proliferation J:168902
Tigittm1Sdl/Tigittm1Sdl
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: C57BL/6)
decreased interleukin-10 secretion J:168902
increased susceptibility to experimental autoimmune encephalomyelitis J:168902
Timd2tm1(GAL4)Pdre/Timd2tm1(GAL4)Pdre
(C.129S4-Timd2tm1(GAL4)Pdre)
abnormal inflammatory response J:125054
abnormal interleukin secretion J:125054
increased eosinophil cell number J:125054
increased interferon-gamma secretion J:125054
increased lymphocyte cell number J:125054
increased tumor necrosis factor secretion J:125054
Timd4tm1Kuch/Timd4tm1Kuch
(C57BL/6-Timd4tm1Kuch)
abnormal B cell physiology J:160747
abnormal macrophage physiology J:160747
increased anti-double stranded DNA antibody level J:160747
increased IgA level J:160747
increased IgG2a level J:160747
increased IgG2b level J:160747
increased interferon-gamma secretion J:160747
increased interleukin-17 secretion J:160747
increased splenocyte proliferation J:160747
Timd4tm1Kuch/Timd4tm1Kuch
(involves: C57BL/6)
abnormal circulating chemokine level J:235399
decreased circulating interleukin-10 level J:235399
increased anti-double stranded DNA antibody level J:235399
increased circulating interleukin-1 beta level J:235399
increased circulating interleukin-6 level J:235399
increased circulating interleukin-12b level J:235399
increased susceptibility to systemic lupus erythematosus J:235399
Timd4tm1Osa/Timd4tm1Osa
(involves: C57BL/6)
immune system phenotype J:187181
impaired macrophage phagocytosis J:187181
Timd4tm1Wouy/Timd4tm1Wouy
(involves: 129)
abnormal macrophage physiology J:160304
decreased tumor necrosis factor secretion J:160304
impaired macrophage phagocytosis J:160304
increased IgG2a level J:160304
increased leukocyte cell number J:160304
increased lymphocyte cell number J:160304
increased tumor necrosis factor secretion J:160304
Timd6tm1b(KOMP)Wtsi/Timd6+
(C57BL/6N-Timd6tm1b(KOMP)Wtsi/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Timm13em1(IMPC)Tcp/Timm13+
(C57BL/6NCrl-Timm13em1(IMPC)Tcp/Tcp)
abnormal spleen morphology J:211773
enlarged thymus J:211773
Timmdc1Gt(OST407011)Lex/Timmdc1+
(B6;129S5-Timmdc1Gt(OST407011)Lex/Mmucd)
increased CD4-positive, alpha-beta T cell number J:171883
Timp1tm1Pds/Timp1tm1Pds
(involves: 129S4/SvJae)
decreased susceptibility to bacterial infection J:94836
Timp1tm1Pds/Timp1tm1Pds
(involves: C57BL/6)
decreased susceptibility to bacterial infection J:94836
Timp1tm1Pds/Timp1tm1Pds
(involves: 129S4/SvJae * C57BL/6)
increased neutrophil cell number J:112941
lung inflammation J:112941
Timp2em1(IMPC)Hmgu/Timp2em1(IMPC)Hmgu
(C57BL/6N-Timp2em1(IMPC)Hmgu/Ieg)
increased B cell number J:211773
increased B-2 B cell number J:211773
increased follicular B cell number J:211773
Timp2tm1Pds/Timp2tm1Pds
(involves: 129S4/SvJae * C57BL/6)
increased neutrophil cell number J:112941
Timp3tm1Osya/Timp3tm1Osya
(B6.129P2-Timp3tm1Osya)
aortitis J:193744
Timp3tm1Rkho/Timp3tm1Rkho
(B6.129-Timp3tm1Rkho)
increased tumor necrosis factor secretion J:92948
liver inflammation J:92948
Timp3tm1Rkho/Timp3tm1Rkho
Tnftm1Gkl/Tnftm1Gkl

(involves: 129 * 129S/SvEv * C57BL/6)
increased neutrophil cell number J:112033
Timp4em1(IMPC)Mbp/Timp4em1(IMPC)Mbp
(C57BL/6N-Timp4em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Tincrem1(IMPC)Ccpcz/Tincrem1(IMPC)Ccpcz
(C57BL/6NCrl-Tincrem1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Tinf2tm2.2Tdl/Tinf2+
(involves: BALB/cJ * C57BL/6)
dermatitis J:207367
lymphoid hyperplasia J:207367
myeloid hyperplasia J:207367
TiparpGt(ROSA)79Sor/TiparpGt(ROSA)79Sor
(involves: 129S4/SvJaeSor)
kidney inflammation J:117491
TiparpGt(ROSA)79Sor/TiparpGt(ROSA)79Sor
(involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J)
abnormal thymus involution J:250417
Tiparptm1b(EUCOMM)Wtsi/Tiparptm1b(EUCOMM)Wtsi
(C57BL/6N-Tiparptm1b(EUCOMM)Wtsi/Tcp)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tir2BALB/cOlaHsd/Tir2C57BL/6JOlaHsd
(involves: BALB/cOlaHsd * C57BL/6JOlaHsd)
abnormal immune serum protein physiology J:40771
Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd
(involves: A/JOlaHsd * C57BL/6JOlaHsd)
decreased susceptibility to parasitic infection J:40771
Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd
(involves: BALB/cOlaHsd * C57BL/6JOlaHsd)
decreased susceptibility to parasitic infection J:40771
Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd
(A.B6-Tir2)
decreased susceptibility to parasitic infection J:97672
Tir2C57BL/6JOlaHsd/Tir2C57BL/6JOlaHsd
(A.B6-(D5Mit200-D5Mit10))
decreased susceptibility to parasitic infection J:135428
Tir3BALB/cOlaHsd/Tir3C57BL/6JOlaHsd
(involves: BALB/cOlaHsd * C57BL/6JOlaHsd)
decreased susceptibility to parasitic infection J:40771
Tir3C57BL/6JOlaHsd/Tir3C57BL/6JOlaHsd
(involves: BALB/cOlaHsd * C57BL/6JOlaHsd)
decreased susceptibility to parasitic infection J:40771
Tir3C57BL/6JOlaHsd/Tir3C57BL/6JOlaHsd
(A.B6-Tir3)
decreased susceptibility to parasitic infection J:97672
Tir3C57BL/6JOlaHsd/Tir3C57BL/6JOlaHsd
(A.B6-(D1Mit60-D1Mit217))
decreased susceptibility to parasitic infection J:135428
Tir4C57BL/6JOlaHsd/?
(involves: BALB/cOlaHsd * C57BL/6JOlaHsd)
decreased susceptibility to parasitic infection J:40771
Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd
(involves: A/JOlaHsd * C57BL/6JOlaHsd)
decreased susceptibility to parasitic infection J:40771
Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd
(involves: BALB/cOlaHsd * C57BL/6JOlaHsd)
decreased susceptibility to parasitic infection J:40771
Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd
(A.B6-Tir1)
decreased susceptibility to parasitic infection J:97672
Tir4C57BL/6JOlaHsd/Tir4C57BL/6JOlaHsd
(A.B6-(D17Mit29-D17Mit11))
decreased susceptibility to parasitic infection J:135428
Tir9C57BL/6/Tir9C57BL/6
(involves: C57BL/6 * DBA/2)
increased susceptibility to parasitic infection J:84716
Tir10C57BL/6/Tir10C57BL/6
(involves: C57BL/6 * DBA/2)
increased susceptibility to parasitic infection J:84716
Tirapm1Btlr/Tirapm1Btlr
(C57BL/6J-Tirapm1Btlr)
abnormal interferon secretion J:133618
decreased tumor necrosis factor secretion J:133618
Tiraptm1Aki/Tiraptm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:111205
abnormal level of surface class II molecules J:111205
decreased IgG3 level J:137066
Tiraptm1Aki/Tiraptm1Aki
(B6.129P2-Tiraptm1Aki)
abnormal dendritic cell physiology J:118954
decreased interleukin-6 secretion J:118954
decreased interleukin-12b secretion J:118954
Tiraptm1Medz/Tiraptm1Medz
(involves: 129S1/Sv * C57BL/6)
abnormal dendritic cell physiology J:96773
abnormal macrophage physiology J:96773
decreased B cell proliferation J:96773
Tiraptm1Medz/Tiraptm1Medz
(involves: 129S1/Sv)
abnormal macrophage physiology J:96018
increased susceptibility to bacterial infection J:96018
Tk1tm1Vnd/Tk1tm1Vnd
(involves: 129P2/OlaHsd * C57BL/6)
arteritis J:101669
liver inflammation J:101669
lung inflammation J:101669
lymph node atrophy J:101669
small spleen J:101669
spleen hypoplasia J:101669
thyroid gland inflammation J:101669
Tkfcem1(IMPC)Ccpcz/Tkfcem1(IMPC)Ccpcz
(C57BL/6NCrl-Tkfcem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Tktl1tm1Arte/Tktl1tm1Arte
(C57BL/6-Tktl1tm1Arte)
increased susceptibility to induced colitis J:171154
Tle3em1(IMPC)Mbp/Tle3em1(IMPC)Mbp
(C57BL/6N-Tle3em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Tle4em1(IMPC)Mbp/Tle4em1(IMPC)Mbp
(C57BL/6NCrl-Tle4em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Tle4tm1.2Dasw/Tle4tm1.2Dasw
(B6.129S6(Cg)-Tle4tm1.2Dasw)
abnormal lymphopoiesis J:219243
abnormal thymus morphology J:219243
decreased B cell number J:219243
decreased DN2 thymocyte number J:219243
decreased double-positive T cell number J:219243
decreased follicular B cell number J:219243
decreased leukocyte cell number J:219243
decreased lymphocyte cell number J:219243
decreased pre-pro B cell number J:219243
decreased spleen B cell follicle number J:219243
immune system phenotype J:219243
increased NK T cell number J:219243
increased thymocyte apoptosis J:219243
spleen hypoplasia J:219243
thymus atrophy J:219243
thymus hypoplasia J:219243
Tlf2NOD/Smrf/?
(involves: NOD/Smrf * NON/Lt)
increased CD8-positive, alpha-beta T cell number J:49676
TlfNOD/Smrf/?
(involves: NOD/Smrf * NON/Lt)
increased CD4-positive, alpha-beta T cell number J:49676
Tll1b2b2476Clo/Tll1b2b2476Clo
(C57BL/6J-Tll1b2b2476Clo)
thymus hypoplasia J:175213
Tln1tm4.1Crit/Tln1tm4.1Crit
Tg(Mx1-cre)1Cgn/0

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:134784
Tlr1tm1Aki/Tlr1tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:103395
decreased interleukin-6 secretion J:103395
decreased tumor necrosis factor secretion J:103395
Tlr1tm1Flv/Tlr1tm1Flv
(involves: 129S1/Sv)
abnormal macrophage physiology J:95726
decreased immunoglobulin level J:95726
increased susceptibility to bacterial infection J:95726
Tlr2lngd/Tlr2lngd
(C57BL/6J-Tlr2lngd)
abnormal macrophage physiology J:94077
increased susceptibility to bacterial infection J:94077
Tlr2tm1Aki/Tlr2tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal chemokine level J:88174
abnormal macrophage physiology J:76115, J:95726
abnormal tumor necrosis factor level J:124334
decreased immunoglobulin level J:95726
decreased interleukin-6 secretion J:76115, J:88174
decreased microglial cell activation J:122551
decreased susceptibility to Herpesvirales infection J:88174
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:88174
decreased tumor necrosis factor secretion J:76115
immune system phenotype J:76115
increased susceptibility to bacterial infection J:95726
Tlr2tm1Aki/Tlr2tm1Aki
(B6.129P2-Tlr2tm1Aki)
abnormal dendritic cell physiology J:118954
abnormal interleukin level J:118954
decreased interleukin-6 secretion J:118954
decreased interleukin-12b secretion J:118954
decreased susceptibility to parasitic infection J:116763
increased T cell number J:118954
Tlr2tm1Aki/Tlr2tm1Aki
(involves: 129P2/OlaHsd)
abnormal cytokine secretion J:70578
abnormal leukocyte migration J:171379
abnormal macrophage physiology J:103464, J:130138, J:70578
abnormal osteoclast physiology J:130138
decreased circulating interleukin-1 beta level J:119941
decreased circulating tumor necrosis factor level J:119941
decreased inflammatory response J:146111
decreased interleukin-6 secretion J:70578
decreased interleukin-12 secretion J:70578
decreased susceptibility to bacterial infection induced morbidity/mortality J:146111
decreased tumor necrosis factor secretion J:103395, J:70578
increased B cell apoptosis J:135830
Tlr2tm1Aki/Tlr2tm1Aki
(NOD.129P2-Tlr2tm1Aki)
insulitis J:124334
Tlr2tm1Aki/Tlr2tm1Aki
(C.129P2-Tlr2tm1Aki)
immune system phenotype J:178054
Tlr2tm1Aki/Tlr2tm1Aki
Tlr4tm1Aki/Tlr4tm1Aki

(B6.129P2-Tlr2tm1Aki Tlr4tm1Aki)
abnormal chemokine secretion J:102879
Tlr2tm1Aki/Tlr2tm1Aki
Tlr4tm1Aki/Tlr4tm1Aki

(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:117688
abnormal macrophage physiology J:117688
decreased IgG3 level J:117688
Tlr2tm1Aki/Tlr2tm1Aki
Tlr6tm1Aki/Tlr6tm1Aki

(involves: 129P2/OlaHsd * C57BL/6)
decreased interleukin-6 secretion J:70578
Tlr2tm1Kir/Tlr2tm1Kir
(either: (involves: 129/Sv * C57BL/6) or (involves: 129/Sv * C57BL/6 * C57BL/6J))
abnormal innate immunity J:85323
abnormal macrophage physiology J:85323
decreased interleukin-6 secretion J:85323
decreased interleukin-10 secretion J:85323
decreased macrophage cytokine production J:85323
decreased macrophage nitric oxide production J:85323
increased susceptibility to bacterial infection J:85323
Tlr2tm1Kir/Tlr2tm1Kir
(Not Specified)
abnormal macrophage physiology J:96018
increased susceptibility to bacterial infection J:96018
Tlr2tm1Kir/Tlr2tm1Kir
(B6.129-Tlr2tm1Kir)
abnormal cellular extravasation J:171028
abnormal cytokine secretion J:121930
decreased circulating tumor necrosis factor level J:162168
decreased interleukin-1 beta secretion J:129871
decreased interleukin-6 secretion J:129871
decreased splenocyte proliferation J:121930
decreased susceptibility to bacterial infection induced morbidity/mortality J:121930
decreased tumor necrosis factor secretion J:129871
increased susceptibility to induced colitis J:165105
Tlr2tm1Kir/Tlr2tm1Kir
(involves: 129)
abnormal interleukin secretion J:94463
decreased interleukin-1 secretion J:94463
decreased interleukin-6 secretion J:94463
decreased tumor necrosis factor secretion J:94463
increased susceptibility to bacterial infection induced morbidity/mortality J:147177
Tlr2tm1Kir/Tlr2tm1Kir
Tlr4Lps-d/Tlr4Lps-d

(C3.Cg-Tlr2tm1Kir Tlr4Lps-d)
abnormal macrophage physiology J:121930
Tlr3M1Btlr/Tlr3+
(C57BL/6J-Tlr3M1Btlr)
decreased macrophage cytokine production J:224670
decreased tumor necrosis factor secretion J:224670
Tlr3M1Btlr/Tlr3M1Btlr
(C57BL/6J-Tlr3M1Btlr)
decreased macrophage cytokine production J:224670
decreased tumor necrosis factor secretion J:224670
Tlr3M2Btlr/Tlr3+
(C57BL/6J-Tlr3M2Btlr)
decreased tumor necrosis factor secretion J:254925
Tlr3M2Btlr/Tlr3M2Btlr
(C57BL/6J-Tlr3M2Btlr)
decreased tumor necrosis factor secretion J:254925
Tlr3tm1Aki/Tlr3tm1Aki
(involves: 129P2/OlaHsd)
abnormal dendritic cell physiology J:114555
immune system phenotype J:144400
Tlr3tm1Aki/Tlr3tm1Aki
Tlr7tm1Aki/Tlr7tm1Aki

(involves: 129P2/OlaHsd)
decreased interferon-alpha secretion J:144400
Tlr3tm1Flv/Tlr3tm1Flv
(involves: 129S1/Sv * C57BL/6)
abnormal B cell physiology J:72167
abnormal macrophage physiology J:72167
decreased inflammatory response J:72167
immune system phenotype J:72167
Tlr3tm1Flv/Tlr3tm1Flv
(involves: C57BL/6)
abnormal macrophage physiology J:86617
immune system phenotype J:86617
Tlr3tm1Flv/Tlr3tm1Flv
(Not Specified)
abnormal cytokine secretion J:88906
abnormal NK cell physiology J:88906
abnormal NK T cell physiology J:88906
increased susceptibility to Herpesvirales infection J:88906
Tlr3tm1Flv/Tlr3tm1Flv
(involves: 129S1/Sv)
abnormal cytokine level J:119967
abnormal interferon level J:119967
abnormal interleukin level J:119967
abnormal tumor necrosis factor level J:119967
decreased susceptibility to Riboviria infection J:136330
decreased susceptibility to Riboviria infection induced morbidity/mortality J:136330
heart inflammation J:119967
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:119967
Tlr3tm1Flv/Tlr3tm1Flv
(B6.129S1-Tlr3tm1Flv/Apb)
abnormal cytokine level J:129533
abnormal interleukin level J:126415
decreased interferon-beta secretion J:251008
Tlr3tm1Flv/Tlr3tm1Flv
(B6N.129S1-Tlr3tm1Flv/J)
increased susceptibility to Coronaviridae infection J:288471
Tlr4Lps-2Btlr/?
(C57BL/6J-Tlr4Lps-2Btlr)
decreased tumor necrosis factor secretion J:147339
Tlr4Lps-2Btlr/Tlr4+
(C57BL/6J-Tlr4Lps-2Btlr)
decreased interleukin-1 beta secretion J:147339
Tlr4lps-2J/Tlr4lps-2J
(BXD29-Tlr4lps-2J/J)
abnormal inflammatory response J:107391
Tlr4Lps-3Btlr/Tlr4+
(C57BL/6J-Tlr4Lps-3Btlr)
decreased interferon-beta secretion J:217295
decreased tumor necrosis factor secretion J:217295
Tlr4Lps-3Btlr/Tlr4Lps-3Btlr
(C57BL/6J-Tlr4Lps-3Btlr)
decreased interferon-beta secretion J:217295
decreased tumor necrosis factor secretion J:217295
Tlr4lps-4Btlr/Tlr4+
(C57BL/6J-Tlr4lps-4Btlr)
decreased macrophage cytokine production J:224664
decreased tumor necrosis factor secretion J:224664
Tlr4lps-4Btlr/Tlr4lps-4Btlr
(C57BL/6J-Tlr4lps-4Btlr)
decreased macrophage apoptosis J:224664
decreased macrophage cytokine production J:224664
decreased tumor necrosis factor secretion J:224664
Tlr4lps-5Btlr/Tlr4lps-5Btlr
(C57BL/6J-Tlr4lps-5Btlr)
decreased B cell number J:224666
decreased macrophage cytokine production J:224666
decreased memory B cell number J:224666
decreased tumor necrosis factor secretion J:224666
Tlr4Lps-6Btlr/Tlr4+
(C57BL/6J-Tlr4Lps-6Btlr)
decreased macrophage cytokine production J:224667
decreased tumor necrosis factor secretion J:224667
Tlr4Lps-6Btlr/Tlr4Lps-6Btlr
(C57BL/6J-Tlr4Lps-6Btlr)
decreased macrophage cytokine production J:224667
decreased tumor necrosis factor secretion J:224667
Tlr4lps-7Btlr/Tlr4+
(C57BL/6J-Tlr4Lps-7Btlr)
decreased interleukin-1 beta secretion J:234239
decreased macrophage cytokine production J:234239
decreased tumor necrosis factor secretion J:234239
Tlr4lps-7Btlr/Tlr4lps-7Btlr
(C57BL/6J-Tlr4Lps-7Btlr)
decreased interleukin-1 beta secretion J:234239
decreased macrophage cytokine production J:234239
decreased tumor necrosis factor secretion J:234239
Tlr4Lps-8Btlr/Tlr4+
(C57BL/6J-Tlr4Lps-8Btlr)
decreased interleukin-1 beta secretion J:234241
decreased macrophage cytokine production J:234241
decreased tumor necrosis factor secretion J:234241
Tlr4Lps-8Btlr/Tlr4Lps-8Btlr
(C57BL/6J-Tlr4Lps-8Btlr)
decreased interleukin-1 beta secretion J:234241
decreased macrophage cytokine production J:234241
decreased tumor necrosis factor secretion J:234241
Tlr4lps-Btlr/Tlr4lps-Btlr
(C57BL/6J-Tlr4lps-Btlr)
abnormal macrophage physiology J:128416
Tlr4Lps-d/Tlr4Lps-d
(involves: C3H/HeJ)
abnormal osteoclast differentiation J:131353
abnormal T-helper 2 physiology J:96356
abnormal tumor necrosis factor level J:124334, J:114368
increased susceptibility to bacterial infection J:5721, J:51522, J:87807
increased susceptibility to induced arthritis J:96356
Tlr4Lps-d/Tlr4Lps-d
(C3H/HeJ-Tlr4Lps-d)
abnormal cytokine level J:96680
abnormal interleukin level J:96680
abnormal macrophage chemotaxis J:122597
abnormal microglial cell physiology J:99051
abnormal phagocyte morphology J:125179
abnormal spleen weight J:37271
abnormal susceptibility to infection J:162716
abnormal tumor necrosis factor level J:96680
immune system phenotype J:209808
increased circulating interleukin-6 level J:37271
increased susceptibility to Poxviridae infection induced morbidity/mortality J:162716
liver inflammation J:135830
lung inflammation J:96680
Tlr4Lps-d/Tlr4Lps-d
Tg(IghelMD4)4Ccg/0
Tg(KLK4mHEL)6Ccg/0

(involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6)
decreased B cell number J:115059
increased B-1 B cell number J:115059
Tlr4lps-del/Tlr4lps-del
(C57BL/10ScCr)
abnormal cytokine secretion J:88996
abnormal macrophage physiology J:88996
increased susceptibility to bacterial infection J:51522, J:88996
Tlr4lps-del/Tlr4lps-del
(C57BL/10ScN)
increased spleen weight J:37271
Tlr4lps-del/Tlr4lps-del
(involves: C57BL/10ScN)
abnormal tumor necrosis factor level J:114368
decreased interleukin-6 secretion J:147023
decreased interleukin-10 secretion J:147023
Tlr4lps-hypo/Tlr4lps-hypo
(B6.Cg-Tlr4lps-hypo Cln8mnd)
decreased susceptibility to bacterial infection J:103167
Tlr4lps-n/Tlr4lps-n
(C3H/HeN)
decreased acute inflammation J:37271
immune system phenotype J:5557
increased spleen weight J:37271
Tlr4tm1.1Djh/Tlr4tm1.1Djh
(involves: FVB/N)
decreased susceptibility to endotoxin shock J:192520
Tlr4tm1Aki/Tlr4lps-2J
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2J)
abnormal inflammatory response J:107391
Tlr4tm1Aki/Tlr4tm1Aki
(involves: 129P2/OlaHsd)
decreased circulating interleukin-6 level J:145306
decreased susceptibility to Orthomyxoviridae infection J:145306
increased susceptibility to bacterial infection J:53519
Tlr4tm1Aki/Tlr4tm1Aki
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal acute inflammation J:98224
enlarged mesenteric lymph nodes J:98224
impaired neutrophil chemotaxis J:98224
increased susceptibility to bacterial infection J:98224
Tlr4tm1Aki/Tlr4tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal level of surface class II molecules J:76115
abnormal macrophage physiology J:76115
decreased B cell proliferation J:76115
decreased interleukin-6 secretion J:76115
decreased susceptibility to endotoxin shock J:76115
decreased tumor necrosis factor secretion J:76115
increased susceptibility to bacterial infection J:111778
Tlr4tm1Aki/Tlr4tm1Aki
(C.129P2-Tlr4tm1Aki)
decreased susceptibility to induced arthritis J:178054
Tlr4tm1Aki/Tlr4tm1Aki
Tlr5tm1Flv/Tlr5tm1Flv

(involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6)
increased susceptibility to bacterial infection J:111778
Tlr5tm1.1Gewr/Tlr5tm1.1Gewr
Tg(Itgax-cre,-EGFP)4097Ach/?

(involves: C57BL/6J * C57BL/6NTac)
immune system phenotype J:229155
Tlr5tm1Aki/Tlr5tm1Aki
(B6.129P2-Tlr5tm1Aki)
decreased interleukin-6 secretion J:112391
decreased interleukin-12b secretion J:112391
decreased susceptibility to bacterial infection J:112391
immune system phenotype J:116763
Tlr5tm1Aki/Tlr5tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:112671
Tlr5tm1Aki/Tlr5tm1Aki
(involves: 129P2/OlaHsd)
enlarged spleen J:229155
increased interleukin-1 beta secretion J:229155
increased susceptibility to colitis induced morbidity/mortality J:229155
Tlr5tm1Flv/Tlr5tm1Flv
(involves: 129S1/Sv * C57BL/6)
abnormal cytokine secretion J:111778
abnormal dendritic cell physiology J:111778
abnormal response to transplant J:111778
decreased neutrophil cell number J:111778
increased susceptibility to autoimmune diabetes J:158055
increased susceptibility to bacterial infection J:111778
increased susceptibility to induced colitis J:158055
increased susceptibility to induced pancreatitis J:158055
lung inflammation J:111778
Tlr5tm1Flv/Tlr5tm1Flv
(involves: 129S1/Sv)
abnormal leukocyte migration J:171379
Tlr6int/Tlr6int
(C57BL/6-Tlr6int)
abnormal adaptive immunity J:110094
abnormal cell-mediated immunity J:110094
abnormal innate immunity J:110094
abnormal macrophage physiology J:110094
Tlr6m2Btlr/Tlr6m2Btlr
(C57BL/6J-Tlr6m2Btlr)
abnormal macrophage physiology J:144166
decreased tumor necrosis factor secretion J:144166
Tlr6m3Btlr/Tlr6m3Btlr
(C57BL/6J-Tlr6m3Btlr)
abnormal macrophage physiology J:144167
decreased tumor necrosis factor secretion J:144167
Tlr6m4Btlr/Tlr6m4Btlr
(C57BL/6J-Tlr6m4Btlr)
abnormal macrophage physiology J:144168
decreased tumor necrosis factor secretion J:144168
Tlr6tm1Aki/Tlr6tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:70578
abnormal macrophage physiology J:70578
decreased interleukin-6 secretion J:70578
decreased interleukin-12 secretion J:70578
decreased tumor necrosis factor secretion J:70578
Tlr7em2Anu/Y
(C57BL/6NCrl-Tlr7em2Anu)
abnormal B cell physiology J:324448
abnormal macrophage physiology J:324448
abnormal Peyer's patch morphology J:324448
decreased B cell apoptosis J:324448
decreased B cell proliferation J:324448
enlarged spleen J:324448
increased anti-double stranded DNA antibody level J:324448
increased anti-nuclear antigen antibody level J:324448
increased anti-single stranded DNA antibody level J:324448
increased autoantibody level J:324448
increased CD4-positive, alpha-beta T cell number J:324448
increased circulating interferon-gamma level J:324448
increased circulating interleukin-6 level J:324448
increased circulating interleukin-10 level J:324448
increased circulating tumor necrosis factor level J:324448
increased effector memory CD4-positive, alpha-beta T cell number J:324448
increased susceptibility to systemic lupus erythematosus J:324448
increased T follicular helper cell number J:324448
liver inflammation J:324448
lung inflammation J:324448
lymph node inflammation J:324448
Tlr7em2Anu/Tlr7+
(C57BL/6NCrl-Tlr7em2Anu)
abnormal mature B cell morphology J:324448
abnormal plasmacytoid dendritic cell physiology J:324448
decreased marginal zone B cell number J:324448
enlarged spleen J:324448
increased anti-double stranded DNA antibody level J:324448
increased anti-nuclear antigen antibody level J:324448
increased anti-single stranded DNA antibody level J:324448
increased autoantibody level J:324448
increased B cell number J:324448
increased CD4-positive, alpha-beta T cell number J:324448
increased circulating interferon-gamma level J:324448
increased circulating interleukin-6 level J:324448
increased circulating interleukin-10 level J:324448
increased circulating tumor necrosis factor level J:324448
increased germinal center B cell number J:324448
increased plasma cell number J:324448
increased spleen germinal center number J:324448
increased T follicular helper cell number J:324448
spleen hyperplasia J:324448
Tlr7em2Anu/Tlr7em2Anu
(C57BL/6NCrl-Tlr7em2Anu)
abnormal mature B cell morphology J:324448
abnormal Peyer's patch morphology J:324448
abnormal plasmacytoid dendritic cell physiology J:324448
decreased leukocyte cell number J:324448
decreased marginal zone B cell number J:324448
enlarged spleen J:324448
glomerulonephritis J:324448
increased anti-nuclear antigen antibody level J:324448
increased anti-single stranded DNA antibody level J:324448
increased B cell number J:324448
increased CD4-positive, alpha-beta T cell number J:324448
increased effector memory CD4-positive, alpha-beta T cell number J:324448
increased germinal center B cell number J:324448
increased inflammatory response J:324448
increased plasma cell number J:324448
increased spleen germinal center number J:324448
increased susceptibility to systemic lupus erythematosus J:324448
increased T follicular helper cell number J:324448
liver inflammation J:324448
lung inflammation J:324448
lymph node inflammation J:324448
pancreas inflammation J:324448
salivary gland inflammation J:324448
spleen hyperplasia J:324448
Tlr7rsq1/Y
(C57BL/6J-Tlr7rsq1)
abnormal macrophage physiology J:128404
decreased tumor necrosis factor secretion J:128404
Tlr7rsq1/Tlr7rsq1
(C57BL/6J-Tlr7rsq1)
abnormal macrophage physiology J:128404
decreased tumor necrosis factor secretion J:128404
Tlr7rsq2/Y
(C57BL/6J-Tlr7rsq2)
abnormal macrophage physiology J:140020
decreased tumor necrosis factor secretion J:140020
Tlr7tm1Aki/Tlr7tm1Aki
(B6.129P2-Tlr7tm1Aki)
abnormal dendritic cell physiology J:118954
decreased interleukin-12b secretion J:118954
Tlr7tm1Aki/Tlr7tm1Aki
(involves: 129P2/OlaHsd)
decreased interferon-alpha secretion J:144400
Tlr7tm1Flv/Y
(B6.129S1-Tlr7tm1Flv)
decreased splenocyte proliferation J:127600
increased marginal zone B cell number J:127600
Tlr7tm1Flv/Tlr7tm1Flv
(involves: 129S1/Sv)
decreased circulating interferon-alpha level J:89257
Tlr7tm1Flv/Tlr7tm1Flv
(B6.129S1-Tlr7tm1Flv)
decreased anti-insulin autoantibody level J:165267
decreased IgG1 level J:165267
decreased IgG2a level J:165267
decreased IgG level J:165267
decreased IgM level J:165267
Tlr8/Tlr7tm1Vlcg/Tlr8/Tlr7tm1Vlcg
(B6.Cg-Tlr8/Tlr7tm1Vlcg)
decreased anti-insulin autoantibody level J:165267
decreased follicular B cell number J:165267
increased marginal zone B cell number J:165267
Tlr8/Tlr7tm1Vlcg/Tlr7+
Tlr8/Tlr7tm1Vlcg/Tlr8tm1Vlcg

(B6.Cg-Tlr8/Tlr7tm1Vlcg Tlr8tm1Vlcg)
abnormal spleen marginal zone morphology J:165267
decreased anti-insulin autoantibody level J:165267
decreased IgG level J:165267
decreased IgM level J:165267
decreased marginal zone B cell number J:165267
increased IgG level J:165267
increased IgM level J:165267
increased marginal zone B cell number J:165267
Tlr8/Tlr7tm1Vlcg/Tlr8/Tlr7tm1Vlcg
(B6.Cg-Tlr8/Tlr7tm1Vlcg Tlr8tm1Vlcg)
decreased anti-insulin autoantibody level J:165267
decreased follicular B cell number J:165267
increased marginal zone B cell number J:165267
Tlr8tm1Vlcg/Tlr8tm1Vlcg
(B6.129S1-Tlr8tm1Vlcg)
abnormal spleen marginal zone morphology J:165267
decreased B-1a cell number J:165267
decreased B-1b cell number J:165267
decreased dendritic cell number J:165267
decreased IgG1 level J:165267
decreased marginal zone B cell number J:165267
enlarged spleen J:165267
glomerulonephritis J:165267
increased anti-double stranded DNA antibody level J:165267
increased anti-nuclear antigen antibody level J:165267
increased B-2 B cell number J:165267
increased circulating interleukin-12 level J:165267
increased IgG2a level J:165267
increased IgG level J:165267
increased IgM level J:165267
increased interleukin-6 secretion J:165267
increased spleen weight J:165267
Tlr9M1Btlr/Tlr9M1Btlr
(involves: C57BL/6)
abnormal cytokine secretion J:88906
abnormal macrophage physiology J:88906
abnormal NK cell physiology J:88906
abnormal NK T cell physiology J:88906
increased susceptibility to Herpesvirales infection J:88906
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:88906
Tlr9M2Btlr/Tlr9+
(C57BL/6J-Tlr9M2Btlr)
abnormal macrophage physiology J:128405
Tlr9M2Btlr/Tlr9M2Btlr
(C57BL/6J-Tlr9M2Btlr)
abnormal macrophage physiology J:128405
increased susceptibility to Herpesvirales infection J:128405
Tlr9m3Btlr/Tlr9m3Btlr
(C57BL/6J-Tlr9m3Btlr)
abnormal macrophage physiology J:128406
decreased B cell proliferation J:128406
Tlr9m4Btlr/Tlr9+
(C57BL/6J-Tlr9m4Btlr)
abnormal macrophage physiology J:132489
abnormal plasmacytoid dendritic cell physiology J:132489
decreased B cell proliferation J:132489
Tlr9M5Btlr/?
(C57BL/6J-Tlr9M5Btlr)
abnormal macrophage physiology J:147856
decreased tumor necrosis factor secretion J:147856
Tlr9M5Btlr/Tlr9+
(C57BL/6J-Tlr9M5Btlr)
decreased interferon-alpha secretion J:147856
decreased interferon-beta secretion J:147856
Tlr9m6Btlr/Tlr9m6Btlr
(C57BL/6J-Tlr9m6Btlr)
increased susceptibility to induced colitis J:155728
Tlr9M7Btlr/Tlr9+
(C57BL/6J-Tlr9M7Btlr)
decreased tumor necrosis factor secretion J:165701
Tlr9M7Btlr/Tlr9M7Btlr
(C57BL/6J-Tlr9M7Btlr)
decreased tumor necrosis factor secretion J:165701
Tlr9M8Btlr/Tlr9M8Btlr
(involves: C57BL/6J)
decreased interferon-gamma secretion J:168138
Tlr9M9Btlr/Tlr9+
(C57BL/6J-Tlr9M9Btlr)
decreased tumor necrosis factor secretion J:220063
Tlr9M9Btlr/Tlr9M9Btlr
(C57BL/6J-Tlr9M9Btlr)
decreased tumor necrosis factor secretion J:220063
Tlr9tm1Aki/Tlr9tm1Aki
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell physiology J:66049
abnormal dendritic cell physiology J:66049
abnormal macrophage physiology J:117688, J:66049
abnormal T-helper 1 physiology J:66049
decreased inflammatory response J:66049
immune system phenotype J:66049
Tlr9tm1Aki/Tlr9tm1Aki
(involves: 129P2/OlaHsd * BALB/c * C57BL/6)
abnormal dendritic cell physiology J:88244
Tlr9tm1Aki/Tlr9tm1Aki
(B6.129P2-Tlr9tm1Aki)
abnormal immune system physiology J:121070
abnormal response to infection J:121070
decreased interferon-alpha secretion J:125611
decreased interferon-beta secretion J:125611
decreased interleukin-12b secretion J:125611, J:118954
decreased susceptibility to experimental autoimmune encephalomyelitis J:105435
decreased susceptibility to parasitic infection J:116763
decreased tumor necrosis factor secretion J:121070
impaired natural killer cell mediated cytotoxicity J:125611
Tlr9tm1Aki/Tlr9tm1Aki
(involves: 129P2/OlaHsd)
abnormal leukocyte migration J:171379
Tlr9tm1Aki/Tlr9tm1Aki
Tg(IghelMD4)4Ccg/0
Tg(KLK4mHEL)6Ccg/0

(involves: 129P2/OlaHsd * C57BL/6)
decreased mature B cell number J:115059
increased B-1 B cell number J:115059
Tlr12tm1Gho/Tlr12tm1Gho
(Not Specified)
abnormal macrophage physiology J:89754
increased susceptibility to bacterial infection J:89754
Tlr13m1Btlr/Tlr13m1Btlr
(C57BL/6J-Tlr13m1Btlr)
immune system phenotype J:156849
tlss/tlss
(Not Specified)
enlarged mesenteric lymph nodes J:169366
enlarged spleen J:169366
enlarged thymus J:169366
Tlx1tm1.1(cre/ERT2)Rygo/Tlx1tm1.1(cre/ERT2)Rygo
(involves: C57BL/6 * C57BL/6JJcl * C57BL/6NSlc)
absent spleen J:217489
Tlx1tm1Sjk/Tlx1tm1Sjk
(involves: 129S2/SvPas)
abnormal spleen development J:17695
abnormal spleen mesenchyme morphology J:17695
absent spleen J:17695
increased leukocyte cell number J:17695
increased lymphocyte cell number J:17695
increased neutrophil cell number J:17695
Tlx1tm1Thr/Tlx1tm1Thr
(involves: 129P2/OlaHsd * MF1)
abnormal spleen development J:28700
absent spleen J:28700
increased splenocyte apoptosis J:28700
Tlx3tm1Sjk/Tlx3tm1Sjk
(involves: 129X1/SvJ)
immune system phenotype J:60751
Tm4sf20em1(IMPC)Bay/Tm4sf20em1(IMPC)Bay
(C57BL/6N-Tm4sf20em1(IMPC)Bay/BayMmucd)
decreased spleen weight J:211773
Tm7sf2tm1b(KOMP)Wtsi/Tm7sf2tm1b(KOMP)Wtsi
(C57BL/6N-Tm7sf2tm1b(KOMP)Wtsi/Orl)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Tm9sf2em1(IMPC)Tcp/Tm9sf2+
(C57BL/6N-Tm9sf2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Tmc6tm1.1Les/Tmc6tm1.1Les
(B6.129S6(Cg)-Tmc6tm1.1Les)
decreased CD4-positive, alpha-beta T cell number J:300461
decreased CD8-positive, alpha-beta T cell number J:300461
Tmc7em1(IMPC)Mbp/Tmc7em1(IMPC)Mbp
(C57BL/6NCrl-Tmc7em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tmc8tm1.1Les/Tmc8tm1.1Les
(B6.129S6(Cg)-Tmc8tm1.1Les)
decreased CD4-positive, alpha-beta T cell number J:300461
decreased CD8-positive, alpha-beta T cell number J:300461
Tmcc2em1(IMPC)Mbp/Tmcc2+
(C57BL/6N-Tmcc2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tmco1em1(IMPC)J/Tmco1+
(C57BL/6NJ-Tmco1em1(IMPC)J/J)
increased leukocyte cell number J:211773
Tmem8bem1(IMPC)Tcp/Tmem8b+
(C57BL/6N-Tmem8bem1(IMPC)Tcp/Tcp)
increased basophil cell number J:211773
Tmem30atm1.1Xjz/Tmem30atm1.1Xjz
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6J * DBA)
liver inflammation J:249038
Tmem35atm1.1(KOMP)Vlcg/Y
(B6(FVB)-Tmem35atm1.1(KOMP)Vlcg)
spleen hyperplasia J:244268
Tmem41bem1Cya/Tmem41b+
(involves: C57BL/6)
decreased susceptibility to Coronaviridae infection J:316472
Tmem45aem1(IMPC)Mbp/Tmem45aem1(IMPC)Mbp
(C57BL/6N-Tmem45aem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Tmem60em1(IMPC)Ccpcz/Tmem60em1(IMPC)Ccpcz
(C57BL/6N-Tmem60em1(IMPC)Ccpcz/Ccpcz)
decreased effector memory T-helper cell number J:211773
Tmem64Gt(SYA242)Byg/Tmem64Gt(SYA242)Byg
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:198051
decreased osteoclast cell number J:198051
Tmem74em1(IMPC)Tcp/Tmem74em1(IMPC)Tcp
(C57BL/6NCrl-Tmem74em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
small thymus J:211773
Tmem79ma/Tmem79ma
(involves: C57BL/6JJcl * CBA/CaGr)
dermatitis J:202316
Tmem79ma/Tmem79ma
(B6.CBACaGr-Tmem79ma/J)
blepharitis J:202453
dermatitis J:202453
increased IgE level J:202453
skin inflammation J:202453
Tmem86atm1b(KOMP)Mbp/Tmem86atm1b(KOMP)Mbp
(C57BL/6N-Tmem86atm1b(KOMP)Mbp/Kmpc)
abnormal lymph node morphology J:211773
Tmem88bem1(IMPC)Mbp/Tmem88bem1(IMPC)Mbp
(C57BL/6N-Tmem88bem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
Tmem100tm1e.1(KOMP)Wtsi/Tmem100+
(C57BL/6N-Tmem100tm1e.1(KOMP)Wtsi/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Tmem102tm1.1Jyen/Tmem102tm1.1Jyen
(B6.Cg-Tmem102tm1.1Jyen)
abnormal leukocyte adhesion J:200103
impaired leukocyte migration J:200103
Tmem109tm1Yamt/Tmem109tm1Yamt
(B6.Cg-Tmem109tm1Yamt)
decreased thymocyte apoptosis J:157864
Tmem116tm1b(EUCOMM)Hmgu/Tmem116tm1b(EUCOMM)Hmgu
(C57BL/6N-Tmem116tm1b(EUCOMM)Hmgu/Ieg)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Tmem121bem1(IMPC)Tcp/Tmem121bem1(IMPC)Tcp
(C57BL/6NCrl-Tmem121bem1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Tmem126atm1a(EUCOMM)Wtsi/Tmem126atm1a(EUCOMM)Wtsi
(C57BL/6N-Tmem126atm1a(EUCOMM)Wtsi/Wtsi)
decreased alpha-beta T cell number J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased T-helper cell number J:211773
Tmem127tm1(KOMP)Wtsi/Tmem127tm1(KOMP)Wtsi
(C57BL/6N-Tmem127tm1(KOMP)Wtsi/Wtsi)
decreased B cell number J:211773
decreased B-2 B cell number J:211773
decreased CD4-positive, alpha-beta T cell number J:211773
decreased effector memory CD8-positive, alpha-beta T cell number J:211773
decreased KLRG1-positive NK cell number J:211773
decreased KLRG1-positive T-helper cell number J:211773
decreased Ly6C high monocyte number J:211773
decreased memory-marker NK cell number J:211773
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
decreased NK cell number J:211773
decreased plasmacytoid dendritic cell number J:211773
increased alpha-beta T cell number J:211773
increased CD4-positive, alpha-beta T cell number J:211773
increased CD8-positive, alpha-beta T cell number J:211773
increased CD8-positive, naive alpha-beta T cell number J:211773
increased KLRG1-positive NK cell number J:211773
increased Ly6C low monocyte number J:211773
increased memory-marker NK cell number J:211773
increased T cell number J:211773
Tmem138tm1b(EUCOMM)Wtsi/Tmem138tm1b(EUCOMM)Wtsi
(C57BL/6N-Tmem138tm1b(EUCOMM)Wtsi/BayMmucd)
increased spleen weight J:211773
Tmem150bem1(IMPC)Ccpcz/Tmem150bem1(IMPC)Ccpcz
(C57BL/6N-Tmem150bem1(IMPC)Ccpcz/Ccpcz)
decreased eosinophil cell number J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
Tmem160em1.1Bros/Tmem160em1.1Bros
(involves: C57BL/6JRj * FVB/N)
abnormal cytokine level J:328221
Tmem178tm1Lex/Tmem178tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal osteoclast differentiation J:228311
abnormal osteoclast physiology J:228311
increased osteoclast cell number J:228311
increased susceptibility to induced arthritis J:228311
Tmem184btm1.1(KOMP)Vlcg/Tmem184btm1.1(KOMP)Vlcg
(C57BL/6N-Tmem184btm1.1(KOMP)Vlcg/Ucd)
abnormal lymph node morphology J:211773
Tmem204tm1.1Ali/Tmem204tm1.1Ali
(involves: BALB/c * C57BL/6)
abnormal lymphatic vessel smooth muscle morphology J:159519
enlarged lymphatic vessel J:159519
Tmem204tm1Ali/Tmem204tm1Ali
Tg(Tie1-cre)9Ref/0

(involves: 129S1/Sv * 129X1/SvJ)
enlarged lymphatic vessel J:159519
Tmem209em1(IMPC)Tcp/Tmem209+
(C57BL/6NCrl-Tmem209em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
enlarged spleen J:211773
Tmem219tm1(KOMP)Vlcg/Tmem219tm1(KOMP)Vlcg
(B6J.B6N-Tmem219tm1(KOMP)Vlcg)
immune system phenotype J:236976
increased eosinophil cell number J:236976
increased IgE level J:236976
increased interleukin-4 secretion J:236976
increased interleukin-13 secretion J:236976
Tmem219tm1(KOMP)Vlcg/Tmem219tm1(KOMP)Vlcg
Tg(Scgb1a1-rtTA,tetO-Il13)1Eli/0

(involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA)
lung inflammation J:236976
Tmem225em1(IMPC)Mbp/Tmem225em1(IMPC)Mbp
(C57BL/6N-Tmem225em1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Tmem234tm1Lex/Tmem234tm1Lex
(B6;129S5-Tmem234tm1Lex/Mmucd)
increased IgG2a level J:171883
Tmem237tm1b(EUCOMM)Hmgu/Tmem237+
(C57BL/6N-Tmem237tm1b(EUCOMM)Hmgu/Ccpcz)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Tmem248tm1.1(KOMP)Vlcg/Tmem248tm1.1(KOMP)Vlcg
(C57BL/6N-Tmem248tm1.1(KOMP)Vlcg/Ucd)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
decreased thymus weight J:211773
increased monocyte cell number J:211773
small spleen J:211773
small thymus J:211773
Tmem256tm1.1(KOMP)Vlcg/Tmem256tm1.1(KOMP)Vlcg
(C57BL/6N-Tmem256tm1.1(KOMP)Vlcg/Ucd)
increased monocyte cell number J:211773
Tmem258tm1.1(KOMP)Vlcg/Tmem258+
(involves: C57BL/6NTac)
increased susceptibility to colitis induced morbidity/mortality J:240635
increased susceptibility to induced colitis J:240635
Tmem263em1Gww/Tmem263em1Gww
(C57BL/6J-Tmem263em1Gww)
decreased spleen weight J:345905
Tmevp2C57BL/10SnSg/Tmevp2C57BL/10SnSg
(involves: A/WySn * C57BL/10SnSg * SJL/J * Swiss)
decreased susceptibility to Picornaviridae infection J:54593
Tmevp3C57BL/10SnSg/Tmevp3C57BL/10SnSg
(involves: A/WySn * C57BL/10SnSg * SJL/J * Swiss)
decreased susceptibility to Picornaviridae infection J:54593
Tmevp3C57BL/10SnSg/Tmevp3SJL/J
(involves: A/WySn * C57BL/10SnSg * SJL/J * Swiss)
decreased susceptibility to Picornaviridae infection J:54593
Tmprss2tm1(KOMP)Vlcg/Tmprss2tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal cytokine secretion J:283077
decreased susceptibility to Coronaviridae infection J:283077
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:214427
lung inflammation J:214427
Tmprss2tm1Psn/Tmprss2tm1Psn
(B6JRj.129S1-Tmprss2tm1Psn)
decreased susceptibility to Orthomyxoviridae infection J:287633
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:287633
Tmprss2tm1Psn/Tmprss2tm1Psn
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
decreased susceptibility to Orthomyxoviridae infection J:244166
Tmprss2tm2.1(ETV1)Sho/Tmprss2tm2.1(ETV1)Sho
(involves: C57BL/6 * DBA/2)
prostate gland inflammation J:212219
Tmprss6msk/Tmprss6msk
(C57BL/6J-Tmprss6msk)
decreased spleen iron level J:134446
Tmprss6tm1b(EUCOMM)Wtsi/Tmprss6tm1b(EUCOMM)Wtsi
(C57BL/6N-Tmprss6tm1b(EUCOMM)Wtsi/Ics)
decreased CD8-positive, alpha-beta T cell number J:211773
decreased NK cell number J:211773
immune system phenotype J:211773
increased CD11b-high dendritic cell number J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased Ly6C-positive mature NK cell number J:211773
Tmprss6tm1Dgen/Tmprss6+
(B6.129P2-Tmprss6tm1Dgen/Crl)
decreased spleen iron level J:160248
Tmprss6tm1Dgen/Tmprss6tm1Dgen
(B6.129P2-Tmprss6tm1Dgen/Crl)
decreased spleen iron level J:160248
increased spleen weight J:160248
Tmprss15tm1a(KOMP)Wtsi/Tmprss15tm1a(KOMP)Wtsi
(C57BL/6N-Tmprss15tm1a(KOMP)Wtsi/Wtsi)
increased leukocyte cell number J:175295
Tmsb4xem1(IMPC)Mbp/Tmsb4xem1(IMPC)Mbp
(C57BL/6NCrl-Tmsb4xem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tmub1tm1Lex/Tmub1tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased monocyte cell number J:171883
Tmub2tm1b(KOMP)Wtsi/Tmub2tm1b(KOMP)Wtsi
(C57BL/6N-Tmub2tm1b(KOMP)Wtsi/Tcp)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Tnbs1SJL/J/?
(involves: C57BL/6J * SJL/J)
increased susceptibility to induced colitis J:82095
Tnbs2SJL/J/?
(involves: C57BL/6J * SJL/J)
increased interleukin-12b secretion J:82095
increased susceptibility to induced colitis J:82095
TnfBpsm1/Tnf+
(involves: C57BL/6)
aortic valve inflammation J:226052
increased circulating tumor necrosis factor level J:226052
mitral valve inflammation J:226052
rheumatoid arthritis J:226052
TnfBpsm1/Tnf+
(C.Cg-TnfBpsm1)
aortic valve inflammation J:226052
cardiovalvulitis J:226052
mitral valve inflammation J:226052
TnfBpsm1/Tnf+
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak

(involves: 129S2/SvPas * C57BL/6)
increased circulating tumor necrosis factor level J:226052
TnfBpsm1/TnfBpsm1
(involves: C57BL/6)
accelerated temporomandibular joint osteoarthritis J:226052
aortic valve inflammation J:226052
increased circulating tumor necrosis factor level J:226052
mitral valve inflammation J:226052
rheumatoid arthritis J:226052
TnfBpsm1/TnfBpsm1
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak

(involves: 129S2/SvPas * C57BL/6)
increased circulating tumor necrosis factor level J:226052
Tnfem4Boui/Tnf+
(C57BL/6-Tnfem4Boui)
arthritis J:306876
cardiovalvulitis J:306876
colitis J:306876
esophageal inflammation J:306876
ileum inflammation J:306876
Tnfem5Boui/Tnf+
Tnfrsf1atm1Mak/Tnfrsf1a+

(involves: 129S2/SvPas * C57BL/6)
arthritis J:306876
cardiovalvulitis J:306876
colitis J:306876
TnfM1Btlr/Tnf+
(C57BL/6J-TnfM1Btlr)
decreased follicular dendritic cell number J:124642
immune system phenotype J:124642
TnfM1Btlr/TnfM1Btlr
(C57BL/6J-TnfM1Btlr)
decreased follicular dendritic cell number J:124642
immune system phenotype J:124642
increased susceptibility to bacterial infection J:124642
TnfM2Btlr/Tnf+
(C57BL/6J-TnfM2Btlr)
decreased macrophage cytokine production J:213047
decreased tumor necrosis factor secretion J:213047
TnfR8H/TnfR8H
(involves: I/St)
increased susceptibility to bacterial infection J:114302
Tnftm1.1Sned/Tnftm1.1Sned
Cd19tm1(cre)Cgn/Cd19+

(involves: 129 * 129P2/OlaHsd * C57BL/6)
immune system phenotype J:95684
Tnftm1.1Sned/Tnftm1.1Sned
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129 * 129P2/OlaHsd * C57BL/6)
abnormal chemokine secretion J:95684
decreased circulating tumor necrosis factor level J:95684
decreased susceptibility to autoimmune disorder J:95684
decreased susceptibility to endotoxin shock J:95684
increased susceptibility to bacterial infection J:95684
Tnftm1.1Sned/Tnftm1.1Sned
Tg(Cd4-cre)1Cwi/0

(involves: 129 * C57BL/6 * DBA/2)
decreased circulating tumor necrosis factor level J:95684
decreased susceptibility to autoimmune disorder J:95684
decreased susceptibility to endotoxin shock J:95684
increased susceptibility to bacterial infection J:95684
Tnftm1.2Sned/Tnftm1.2Sned
(involves: 129/Sv * C57BL/6)
absent Peyer's patches J:97783
decreased susceptibility to bacterial infection J:97783
increased leukocyte cell number J:97783
increased susceptibility to parasitic infection J:97783
Tnftm1Gkl/Tnftm1Gkl
(involves: 129S/SvEv * C57BL/6)
abnormal inflammatory response J:114740
abnormal lymph node B cell domain morphology J:40970
abnormal lymphocyte physiology J:114740
abnormal macrophage physiology J:114740
abnormal mesenteric lymph node morphology J:114740
abnormal Peyer's patch follicle morphology J:40970
abnormal Peyer's patch morphology J:40970
abnormal spleen follicular dendritic cell network J:42579
abnormal spleen primary B follicle morphology J:47673
absent follicular dendritic cells J:40970
absent spleen germinal center J:47673, J:114740
decreased inflammatory response J:56068
decreased Peyer's patch number J:40970
decreased susceptibility to experimental autoimmune encephalomyelitis J:114740
decreased susceptibility to type IV hypersensitivity reaction J:47673
immune system phenotype J:114740
increased susceptibility to bacterial infection J:47673, J:114740
Tnftm1Gkl/Tnftm1Gkl
(involves: 129S/SvEv)
abnormal chemokine secretion J:95684
decreased circulating tumor necrosis factor level J:95684
decreased susceptibility to autoimmune disorder J:95684
decreased susceptibility to endotoxin shock J:95684
increased susceptibility to bacterial infection J:95684
Tnftm1Gkl/Tnftm1Gkl
(either: B6.129-Tnftm1Gkl or (involves: 129 * C57BL/6))
decreased Peyer's patch number J:97783
decreased susceptibility to bacterial infection J:97783
increased leukocyte cell number J:97783
increased lymphocyte cell number J:97783
increased neutrophil cell number J:97783
increased susceptibility to parasitic infection J:97783
small Peyer's patches J:97783
Tnftm1Gkl/Tnftm1Gkl
(involves: 129S/SvEv * C57BL/6J)
abnormal metallophilic macrophage morphology J:124642
abnormal Peyer's patch follicle morphology J:124642
abnormal Peyer's patch germinal center morphology J:124642
abnormal Peyer's patch morphology J:124642
abnormal Peyer's patch T cell area morphology J:124642
abnormal spleen follicular dendritic cell network J:124642
abnormal spleen marginal sinus morphology J:124642
abnormal spleen primary B follicle morphology J:124642
absent spleen germinal center J:124642
decreased Peyer's patch number J:124642
increased susceptibility to bacterial infection J:124642
Tnftm1Gkl/Tnftm1Gkl
Tnfaip3tm1Ama/Tnfaip3tm1Ama

(involves: 129S/SvEv * C57BL/6J)
abnormal cytokine secretion J:92694
abnormal inflammatory response J:92694
Tnftm1Gkl/Tnftm1Gkl
Tnfrsf1atm1.1Gkl/Tnfrsf1atm1.1Gkl

(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:92470
Tnftm1Gkl/Tnftm2Gkl
(involves: 129S/SvEv * C57BL/6)
increased circulating tumor necrosis factor level J:54056
increased susceptibility to endotoxin shock J:54056
increased tumor necrosis factor secretion J:54056
rheumatoid arthritis J:54056
Tnftm1Jods/Tnftm1Jods
(involves: C57BL/6)
abnormal immune system physiology J:98591
abnormal lymph node primary follicle morphology J:98591
abnormal metallophilic macrophage morphology J:98591
abnormal Peyer's patch follicle morphology J:43602
abnormal Peyer's patch morphology J:43602, J:98591
abnormal spleen marginal sinus morphology J:43602
abnormal spleen primary B follicle morphology J:43602, J:98591
abnormal spleen white pulp morphology J:43602, J:98591
absent spleen germinal center J:98591
decreased follicular dendritic cell number J:43602
decreased Peyer's patch number J:43602
decreased susceptibility to endotoxin shock J:98591
decreased susceptibility to experimental autoimmune encephalomyelitis J:44545, J:98591
increased leukocyte cell number J:43602
increased susceptibility to bacterial infection J:115034, J:98170
small Peyer's patches J:43602
Tnftm1Jods/Tnftm1Jods
(C57BL/6-Tnftm1Jods)
abnormal cytokine level J:118417
decreased susceptibility to experimental autoimmune encephalomyelitis J:118417
Tnftm1Jods/Tnftm1Jods
(C57BL/6-Ltatm1Jods)
abnormal spleen B cell follicle morphology J:78229
decreased susceptibility to experimental autoimmune encephalomyelitis J:47428
Tnftm1Ljo/Tnf+
(involves: 129S1/Sv)
increased susceptibility to bacterial infection J:41992
increased susceptibility to fungal infection J:41992
Tnftm1Ljo/Tnftm1Ljo
(involves: 129S1/Sv)
abnormal chemokine secretion J:95684
abnormal cytokine secretion J:41992
abnormal follicular dendritic cell physiology J:41992
abnormal susceptibility to infection J:41992
absent spleen germinal center J:80616, J:41992
decreased circulating tumor necrosis factor level J:95684
decreased IgG level J:41992
decreased spleen B cell follicle number J:95684
decreased spleen white pulp amount J:80616
decreased susceptibility to autoimmune disorder J:95684
decreased susceptibility to endotoxin shock J:95684, J:41992
increased susceptibility to bacterial infection J:80616, J:95684, J:41992
increased susceptibility to fungal infection J:41992
Tnftm1Ljo/Tnftm1Ljo
(either: B6.129-Tnftm1Ljo or (involves: 129 * C57BL/6))
abnormal Peyer's patch follicle morphology J:97783
abnormal Peyer's patch germinal center morphology J:97783
abnormal Peyer's patch T cell area morphology J:97783
absent follicular dendritic cells J:97783
decreased Peyer's patch number J:97783
decreased susceptibility to bacterial infection J:97783
increased leukocyte cell number J:97783
increased lymphocyte cell number J:97783
increased neutrophil cell number J:97783
increased susceptibility to parasitic infection J:97783
small Peyer's patches J:97783
Tnftm1Ljo/Tnftm1Ljo
(B6.129S1-Tnftm1Ljo)
lung inflammation J:127028
Tnftm1Ljo/Tnftm1Ljo
(involves: 129S1/Sv * C57BL/6)
abnormal lymph node cell ratio J:127028
abnormal neutrophil physiology J:127028
decreased immunoglobulin level J:127028
increased interferon-gamma secretion J:127028
increased neutrophil cell number J:127028
increased susceptibility to parasitic infection J:127028
lymph node hypoplasia J:127028
skin inflammation J:127028
Tnftm1Sek/Tnftm1Sek
(B6.Cg-Tnftm1Sek)
abnormal cytokine secretion J:44841
abnormal macrophage physiology J:44841
abnormal mesenteric lymph node morphology J:44841
abnormal Peyer's patch germinal center morphology J:44841
absent lymph node germinal center J:44841
absent spleen germinal center J:44841
decreased circulating interferon-gamma level J:44841
decreased circulating interleukin-1 alpha level J:44841
decreased circulating interleukin-1 beta level J:44841
decreased circulating interleukin-6 level J:44841
decreased susceptibility to endotoxin shock J:44841
immune system phenotype J:44841
Tnftm2.1Gkl/Tnftm2.1Gkl
Tg(Fabp1-cre)1Jig/0

(involves: 129S/SvEv * FVB/N)
ileum inflammation J:204557
increased circulating tumor necrosis factor level J:204557
large intestinal inflammation J:204557
small intestinal inflammation J:204557
Tnftm2.1Gkl/Tnftm2.1Gkl
Tg(Lck-cre)I57Jxm/0

(involves: 129S/SvEv * ICR)
small intestinal inflammation J:108572
Tnftm2Gkl/Tnf+
(involves: 129S/SvEv * C57BL/6)
abnormal alpha-beta intraepithelial T cell morphology J:136667
abnormal CD4-positive, alpha-beta T cell physiology J:136667
abnormal CD8-positive, alpha beta T cell morphology J:136667
abnormal circulating chemokine level J:204922
abnormal T cell physiology J:136667
abnormal T cell subpopulation ratio J:136667
abnormal T-helper 17 cell physiology J:204922
arthritis J:92307, J:136667
decreased inflammatory response J:204922
ileum inflammation J:204922
increased circulating tumor necrosis factor level J:54056, J:204922
increased dendritic cell number J:204922
intestinal inflammation J:136667
rheumatoid arthritis J:54056
small intestinal inflammation J:92307, J:54056, J:204922
Tnftm2Gkl/Tnf+
(involves: 129S/SvEv * C57BL/6 * SPRET/Ei)
arthritis J:92307
small intestinal inflammation J:92307
Tnftm2Gkl/Tnf+
(involves: 129S/SvEv * C57BL/6J)
abnormal cytotoxic T cell physiology J:108572
abnormal myelopoiesis J:108572
abnormal response to transplant J:108572
enlarged spleen J:108572
increased CD8-positive, alpha-beta T cell number J:108572
increased circulating tumor necrosis factor level J:264147
increased tumor necrosis factor secretion J:264147
small intestinal inflammation J:108572
Tnftm2Gkl/Tnf+
(involves: 129S/SvEv * C57BL/6 * CBA)
arthritis J:131930
Tnftm2Gkl/Tnf+
(B6.129S-Tnftm2Gkl/Jarn)
abnormal CD4-positive, alpha-beta T cell physiology J:145626
abnormal CD8-positive, alpha beta T cell morphology J:131978
ileum inflammation J:131978, J:145626
increased CD4-positive, alpha-beta memory T cell number J:145626
increased CD4-positive, alpha-beta T cell number J:145626
increased interferon-gamma secretion J:131978
increased interleukin-2 secretion J:145626
increased tumor necrosis factor secretion J:145626
Tnftm2Gkl/Tnf+
Tnfrsf1atm2Gkl/Tnfrsf1atm2Gkl
Tg(Col6a1-cre)1Gkl/?

(involves: 129S/SvEv * C57BL/6 * CBA)
arthritis J:131930
small intestinal inflammation J:131930
Tnftm2Gkl/Tnf+
Tnfrsf1btm1.1Gkl/Tnfrsf1btm1.1Gkl
Tg(Col6a1-cre)1Gkl/0

(involves: 129S/SvEv * C57BL/6 * C57BL/6J * CBA)
increased circulating tumor necrosis factor level J:264147
increased tumor necrosis factor secretion J:264147
joint inflammation J:264147
Tnftm2Gkl/Tnf+
Tnfrsf1btm1.2Gkl/Tnfrsf1btm1.2Gkl

(involves: 129S/SvEv * C57BL/6 * C57BL/6J)
aortic valve inflammation J:264147
arthritis J:264147
increased circulating tumor necrosis factor level J:264147
increased tumor necrosis factor secretion J:264147
Tnftm2Gkl/Tnf+
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm

(involves: 129S/SvEv * 129S2/SvPas * C57BL/6)
rheumatoid arthritis J:54056
small intestinal inflammation J:54056
Tnftm2Gkl/Tnftm2Gkl
(involves: 129S/SvEv * C57BL/6)
cardiovalvulitis J:226052
increased circulating tumor necrosis factor level J:54056
rheumatoid arthritis J:54056
small intestinal inflammation J:54056
thymus hypoplasia J:54056
Tnftm2Gkl/Tnftm2Gkl
Tnfrsf1atm1Blt/Tnfrsf1atm1Blt

(involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6)
increased circulating tumor necrosis factor level J:54056
increased tumor necrosis factor secretion J:54056
Tnftm2Jods/Tnftm2Jods
(involves: C57BL/6)
abnormal lymph node cell ratio J:127028
decreased immunoglobulin level J:127028
immune system phenotype J:127028
increased susceptibility to bacterial infection J:98170
Tnftm2Jods/Tnftm2Jods
(C57BL/6-Tnftm2Jods)
abnormal immune system physiology J:98591
abnormal lymph node primary follicle morphology J:98591
abnormal metallophilic macrophage morphology J:98591
abnormal Peyer's patch follicle morphology J:98591
abnormal spleen follicular dendritic cell network J:98591
abnormal spleen primary B follicle morphology J:98591
abnormal spleen white pulp morphology J:98591
decreased spleen germinal center number J:98591
decreased spleen germinal center size J:98591
decreased susceptibility to endotoxin shock J:98591
decreased susceptibility to experimental autoimmune encephalomyelitis J:98591
Tnftm3Gkl/Tnftm3Gkl
(involves: 129S/SvEv * C57BL/6)
abnormal lymph node B cell domain morphology J:114740
abnormal lymphocyte physiology J:114740
abnormal mesenteric lymph node morphology J:114740
abnormal spleen primary B follicle morphology J:114740
absent follicular dendritic cells J:114740
absent spleen germinal center J:114740
autoimmune response J:114740
decreased circulating tumor necrosis factor level J:114740
decreased IgG1 level J:114740
decreased susceptibility to bacterial infection J:114740
decreased susceptibility to endotoxin shock J:114740
decreased susceptibility to experimental autoimmune encephalomyelitis J:114740
decreased tumor necrosis factor secretion J:114740
Tnftm3Gkl/Tnftm3Gkl
Zfp36tm1Pjb/Zfp36tm1Pjb

(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:114740
myeloid hyperplasia J:114740
Tnfaip3m1Apb/Tnfaip3m1Apb
(C57BL/6-Tnfaip3m1Apb)
CNS inflammation J:324062
enlarged lymph nodes J:324062
increased effector memory T-helper cell number J:324062
increased macrophage cell number J:324062
increased microglial cell activation J:324062
uterus inflammation J:324062
Tnfaip3tm1.1Gho/Tnfaip3tm1.1Gho
(involves: C57BL/6J)
enlarged spleen J:217021
immune system phenotype J:217021
Tnfaip3tm1.1Gvl/Tnfaip3tm1.1Gvl
Tg(Vil1-cre)997Gum/0

(B6.Cg-Tnfaip3tm1.1Gvl Tg(Vil1-cre)997Gum)
increased circulating interleukin-6 level J:163410
increased susceptibility to induced colitis J:163410
Tnfaip3tm1.1Gvl/Tnfaip3tm1.1Gvl
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak
Tg(Vil1-cre)997Gum/0

(involves: 129S2/SvPas * C57BL/6 * SJL)
decreased susceptibility to induced colitis J:163410
increased susceptibility to induced colitis J:163410
Tnfaip3tm1Ama/Tnfaip3tm1Ama
(involves: C57BL/6J)
abnormal cytokine secretion J:92694
abnormal inflammatory response J:92694
Tnfaip3tm1Ama/Tnfaip3tm1Ama
(Not Specified)
increased granulocyte number J:92931
increased inflammatory response J:92931
increased lymphocyte cell number J:92931
increased macrophage cell number J:92931
intestinal inflammation J:92931
joint inflammation J:92931
kidney inflammation J:92931
liver inflammation J:92931
Tnfaip3tm1Ama/Tnfaip3tm1Ama
Tnfrsf1atm1Imx/Tnfrsf1a+

(involves: C57BL/6J)
abnormal inflammatory response J:92694
Tnfaip3tm1Ama/Tnfaip3tm1Ama
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx

(involves: C57BL/6J)
abnormal inflammatory response J:92694
Tnfaip3tm1Homy/Tnfaip3tm1Homy
Tg(Mx1-cre)1Cgn/?

(involves: 129S6/SvEvTac * C57BL/6J * CBA/J)
abnormal B cell number J:212681
abnormal circulating cytokine level J:212681
abnormal circulating interleukin level J:212681
abnormal myelopoiesis J:212681
abnormal spleen morphology J:212681
enlarged lymph nodes J:212681
increased circulating interferon-gamma level J:212681
increased circulating interleukin-1 beta level J:212681
increased circulating interleukin-6 level J:212681
increased circulating tumor necrosis factor level J:212681
liver inflammation J:212681
lung inflammation J:212681
Tnfaip3tm2Ama/Tnfaip3tm2Ama
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell activation J:163917
abnormal B cell morphology J:163917
abnormal B-1a B cell morphology J:163917
decreased B cell apoptosis J:163917
decreased B cell number J:163917
increased autoantibody level J:163917
increased B cell number J:163917
increased B cell proliferation J:163917
increased germinal center B cell number J:163917
increased IgG level J:163917
increased IgM level J:163917
increased immature B cell number J:163917
increased immunoglobulin level J:163917
increased interleukin-6 secretion J:163917
increased plasma cell number J:163917
increased susceptibility to autoimmune disorder J:163917
increased T cell number J:163917
Tnfaip3tm3.1Ama/Tnfaip3tm3.1Ama
(C57BL/6J-Tnfaip3tm3.1Ama)
abnormal chemokine secretion J:203160
decreased interleukin-6 secretion J:203160
enlarged spleen J:203160
increased B cell number J:203160
increased CD4-positive, alpha-beta T cell number J:203160
increased CD8-positive, alpha-beta T cell number J:203160
increased susceptibility to induced colitis J:203160
myeloid hyperplasia J:203160
Tnfaip3tm4.1Ama/Tnfaip3tm4.1Ama
(C57BL/6J-Tnfaip3tm4.1Ama)
abnormal chemokine secretion J:203160
decreased interleukin-6 secretion J:203160
enlarged spleen J:203160
increased B cell number J:203160
increased CD4-positive, alpha-beta T cell number J:203160
increased CD8-positive, alpha-beta T cell number J:203160
increased susceptibility to induced colitis J:203160
myeloid hyperplasia J:203160
Tnfaip6tm1Cful/Tnfaip6tm1Cful
(involves: 129S6/SvEvTac * BALB/c)
decreased inflammatory response J:193758
Tnfaip8Gt(IST13629C1)Tigm/Tnfaip8Gt(IST13629C1)Tigm
(involves: C57BL/6N)
immune system phenotype J:223320
increased circulating interleukin-6 level J:223320
increased circulating interleukin-17 level J:223320
increased interleukin-1 beta secretion J:223320
increased interleukin-6 secretion J:223320
increased interleukin-17 secretion J:223320
increased neutrophil cell number J:223320
increased susceptibility to induced colitis J:223320
small spleen J:223320
Tnfaip8Gt(IST13629C1)Tigm/Tnfaip8Gt(IST13629C1)Tigm
Tnfaip8l1em1Huwa/Tnfaip8l1em1Huwa

(involves: C57BL/6 * C57BL/6N)
colitis J:342074
decreased spleen weight J:342074
increased leukocyte cell number J:342074
increased T-helper 17 cell number J:342074
Tnfaip8l1em1(IMPC)Mbp/Tnfaip8l1em1(IMPC)Mbp
(C57BL/6N-Tnfaip8l1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Tnfaip8l1em1Huwa/Tnfaip8l1em1Huwa
(C57BL/6-Tnfaip8l1em1Huwa)
increased susceptibility to colitis induced morbidity/mortality J:342074
increased susceptibility to induced colitis J:342074
Tnfaip8l2tm1Yhcn/Tnfaip8l2tm1Yhcn
(129S6/SvEvTac-Tnfaip8l2tm1Yhcn)
abnormal B cell activation J:139785
abnormal B cell physiology J:139785
abnormal CD4-positive, alpha-beta T cell physiology J:139785
abnormal cytotoxic T cell physiology J:139785
abnormal inflammatory response J:139785
abnormal leukocyte morphology J:139785
abnormal macrophage activation involved in immune response J:139785
abnormal myeloid dendritic cell morphology J:139785
abnormal spleen morphology J:139785
abnormal T cell apoptosis J:139785
chronic inflammation J:139785
decreased IgG2a level J:139785
decreased IgG2b level J:139785
enlarged spleen J:139785
increased B cell number J:139785
increased circulating interleukin-1 beta level J:139785
increased circulating interleukin-6 level J:139785
increased circulating interleukin-10 level J:139785
increased circulating interleukin-12 level J:139785
increased circulating tumor necrosis factor level J:139785
increased interferon-gamma secretion J:139785
increased interleukin-1 beta secretion J:139785
increased interleukin-2 secretion J:139785
increased interleukin-4 secretion J:139785
increased interleukin-6 secretion J:139785
increased interleukin-12 secretion J:139785
increased interleukin-17 secretion J:139785
increased spleen white pulp amount J:139785
increased susceptibility to endotoxin shock J:139785
increased T cell number J:139785
increased tumor necrosis factor secretion J:139785
intestinal inflammation J:139785
liver inflammation J:139785
lung inflammation J:139785
lymph node inflammation J:139785
spleen hyperplasia J:139785
Tnfrsf1aem1(IMPC)Ccpcz/Tnfrsf1aem1(IMPC)Ccpcz
(C57BL/6NCrl-Tnfrsf1aem1(IMPC)Ccpcz/Ccpcz)
increased effector memory CD8-positive, alpha-beta T cell number J:211773
increased neutrophil cell number J:211773
increased NK cell number J:211773
Tnfrsf1atm1.1Gkl/Tnfrsf1a+
(involves: 129/Sv * C57BL/6)
liver inflammation J:92470
Tnfrsf1atm1.1Gkl/Tnfrsf1atm1.1Gkl
(involves: 129/Sv * C57BL/6)
abnormal cytokine secretion J:92470
decreased susceptibility to bacterial infection J:92470
increased susceptibility to experimental autoimmune encephalomyelitis J:92470
liver inflammation J:92470
Tnfrsf1atm1.1Gkl/Tnfrsf1atm1.1Gkl
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm

(involves: 129/Sv * C57BL/6)
liver inflammation J:92470
Tnfrsf1atm1Blt/Tnfrsf1a+
(involves: 129P2/OlaHsd)
decreased circulating interleukin-6 level J:210950
Tnfrsf1atm1Blt/Tnfrsf1atm1Blt
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune system physiology J:14424
abnormal lymph node B cell domain morphology J:40970
abnormal Peyer's patch follicle morphology J:40970
abnormal Peyer's patch morphology J:40970
absent follicular dendritic cells J:40970
decreased IgG1 level J:115225
decreased interleukin-6 secretion J:14424
decreased Peyer's patch number J:40970
decreased susceptibility to experimental autoimmune encephalomyelitis J:115225
increased susceptibility to bacterial infection J:14424
increased susceptibility to parasitic infection J:114203
increased susceptibility to type I hypersensitivity reaction J:92307
Tnfrsf1atm1Blt/Tnfrsf1atm1Blt
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
decreased susceptibility to bacterial infection J:50903
Tnfrsf1atm1Blt/Tnfrsf1atm1Blt
(involves: 129P2/OlaHsd)
impaired humoral immune response J:210950
increased susceptibility to bacterial infection induced morbidity/mortality J:210950
Tnfrsf1atm1Blt/Tnfrsf1atm1Blt
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
abnormal lymph node cortex morphology J:119206
abnormal lymph node primary follicle morphology J:119206
abnormal lymph node secondary follicle morphology J:119206
absent lymph node germinal center J:119206
absent spleen germinal center J:119206
decreased IgG1 level J:115225
decreased susceptibility to experimental autoimmune encephalomyelitis J:115225
immune system phenotype J:119206
increased susceptibility to parasitic infection J:114203
small Peyer's patches J:119206
Tnfrsf1atm1Blt/Tnfrsf1atm2Gkl
Tg(Cr2-cre)3Cgn/0

(involves: 129P2/OlaHsd * 129S/SvEv)
immune system phenotype J:113314
Tnfrsf1atm1Imx/Tnfrsf1a+
(involves: C57BL/6)
decreased circulating interleukin-6 level J:210950
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal immune system physiology J:45147
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
(C57BL/6-Tnfrsf1atm1Imx)
decreased inflammatory response J:45147
decreased microglial cell number J:112713
decreased susceptibility to endotoxin shock J:45147
increased circulating tumor necrosis factor level J:45147
increased susceptibility to bacterial infection J:45147
lung inflammation J:120174
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
(C57BL/6-Tnfrsf1atm1Imx/J)
abnormal chemokine secretion J:160543
abnormal follicular dendritic cell morphology J:160543
abnormal macrophage physiology J:160543
decreased circulating interleukin-6 level J:160543
decreased interleukin-6 secretion J:160543
decreased susceptibility to endotoxin shock J:160543
increased circulating tumor necrosis factor level J:160543
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
(involves: C57BL/6)
impaired humoral immune response J:210950
increased susceptibility to bacterial infection induced morbidity/mortality J:210950
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tg(Ins2-Cxcl13)1Cys/0

(involves: C57BL/6 * DBA/2)
abnormal lymph organ development J:110548
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tg(Thy1-APP)3Somm/0

(involves: C57BL/6 * C57BL/6J * DBA/2)
microgliosis J:134832
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tnfrsf1btm1Imx/Tnfrsf1btm1Imx

(involves: 129S7/SvEvBrd * C57BL/6)
decreased inflammatory response J:45147
decreased microglial cell activation J:33864
decreased susceptibility to endotoxin shock J:45147
decreased susceptibility to experimental autoimmune uveoretinitis J:115094
decreased susceptibility to induced arthritis J:120707
increased circulating tumor necrosis factor level J:45147
increased susceptibility to bacterial infection J:58851
osteomyelitis J:58851
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tnfrsf1btm1Imx/Tnfrsf1btm1Imx

(B6.129S-Tnfrsf1btm1Imx Tnfrsf1atm1Imx/J)
decreased susceptibility to Coronaviridae infection J:288523
Tnfrsf1atm1Mak/Tnfrsf1a+
(involves: 129S2/SvPas)
decreased circulating interleukin-6 level J:210950
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak
(involves: 129S2/SvPas * C57BL/6J * DBA/2J)
granulomatous inflammation J:55889
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak
(involves: 129S2/SvPas * C57BL/6J * NOD)
decreased susceptibility to autoimmune diabetes J:64051
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak
(involves: 129S2/SvPas)
abnormal spleen germinal center morphology J:139030
decreased circulating interleukin-6 level J:138824
decreased IgG level J:139030
decreased susceptibility to bacterial infection J:4753, J:121930
impaired humoral immune response J:210950
increased circulating tumor necrosis factor level J:139030
increased susceptibility to bacterial infection induced morbidity/mortality J:4753, J:139030, J:210950
Tnfrsf1atm1Mak/Tnfrsf1atm1Mak
Tnip1Gt(E059E05)Wrst/Tnip1Gt(E059E05)Wrst

(involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)
glomerulonephritis J:180054
increased neutrophil cell number J:180054
increased susceptibility to systemic lupus erythematosus J:180054
spleen hyperplasia J:180054
Tnfrsf1atm1Rsie/Tnfrsf1a+
(B6.Cg-Tnfrsf1atm1Rsie)
increased circulating tumor necrosis factor level J:160543
increased interleukin-6 secretion J:160543
increased susceptibility to endotoxin shock J:160543
Tnfrsf1atm1Rsie/Tnfrsf1atm1Rsie
(B6.Cg-Tnfrsf1atm1Rsie)
abnormal chemokine secretion J:160543
abnormal follicular dendritic cell morphology J:160543
abnormal macrophage physiology J:160543
decreased circulating interleukin-1 beta level J:160543
decreased circulating interleukin-6 level J:160543
decreased interleukin-6 secretion J:160543
decreased susceptibility to endotoxin shock J:160543
increased circulating tumor necrosis factor level J:160543
Tnfrsf1atm2.1Rsie/Tnfrsf1a+
(B6.Cg-Tnfrsf1atm2.1Rsie)
abnormal macrophage physiology J:160543
decreased circulating interleukin-1 beta level J:160543
decreased circulating interleukin-6 level J:160543
decreased interleukin-6 secretion J:160543
increased interleukin-6 secretion J:160543
increased susceptibility to endotoxin shock J:160543
Tnfrsf1atm2.1Rsie/Tnfrsf1a+
(involves: 129S6/SvEvTac)
increased susceptibility to endotoxin shock J:160543
Tnfrsf1atm2.1Rsie/Tnfrsf1atm2.1Rsie
(B6.Cg-Tnfrsf1atm2.1Rsie)
abnormal chemokine secretion J:160543
abnormal macrophage physiology J:160543
decreased circulating interleukin-6 level J:160543
decreased interleukin-6 secretion J:160543
decreased susceptibility to endotoxin shock J:160543
increased circulating tumor necrosis factor level J:160543
Tnfrsf1atm2b(EUCOMM)Wtsi/Tnfrsf1atm2b(EUCOMM)Wtsi
(C57BL/6N-Tnfrsf1atm2b(EUCOMM)Wtsi/H)
decreased monocyte cell number J:211773
decreased neutrophil cell number J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased large unstained cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Tnfrsf1btm1a(EUCOMM)Wtsi/Tnfrsf1btm1a(EUCOMM)Wtsi
(C57BL/6N-Tnfrsf1btm1a(EUCOMM)Wtsi/Ics)
decreased T cell number J:165965
Tnfrsf1btm1Imx/Tnfrsf1btm1Imx
(involves: 129S7/SvEvBrd * C57BL/6)
increased circulating tumor necrosis factor level J:45147
increased inflammatory response J:45147
lung inflammation J:120174
microgliosis J:112713
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm
(B6.129S2-Tnfrsf1btm1Mwm/J)
decreased interferon-gamma secretion J:107039
decreased interleukin-2 secretion J:107039
decreased T cell proliferation J:107039
immune system phenotype J:288523
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm
(involves: 129S2/SvPas * C57BL/6J)
abnormal immune system physiology J:21815
increased susceptibility to bacterial infection J:21815
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm
(involves: 129S2/SvPas * C57BL/6J * NOD)
decreased susceptibility to autoimmune diabetes J:64051
periinsulitis J:64051
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm
(involves: 129S2/SvPas * C57BL/6)
decreased susceptibility to bacterial infection J:50903
increased susceptibility to experimental autoimmune encephalomyelitis J:115225
increased susceptibility to parasitic infection J:114203
Tnfrsf4tm1Mfb/Tnfrsf4tm1Mfb
(involves: 129P2/OlaHsd * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:59204
Tnfrsf4tm1Nik/Tnfrsf4tm1Nik
(involves: 129S4/SvJae * C57BL/6)
abnormal CD4-positive, alpha-beta T cell physiology J:64552
abnormal T-helper 2 physiology J:68588
decreased susceptibility to type I hypersensitivity reaction J:68588
decreased T cell proliferation J:58979, J:64552
immune system phenotype J:58979
Tnfrsf8tm1Mak/Tnfrsf8tm1Mak
(involves: 129P2/OlaHsd * C57BL/6)
enlarged thymus J:62854
immune system phenotype J:62854
increased thymocyte number J:62854
Tnfrsf8tm1Mak/Tnfrsf8tm1Mak
(involves: C57BL/6)
decreased susceptibility to graft versus host disease J:92723
Tnfrsf9em1Ygch/Tnfrsf9em1Ygch
(NOD/ShiLtDvs-Tnfrsf9em1Ygch)
abnormal T cell physiology J:208927
immune system phenotype J:208927
insulitis J:208927
Tnfrsf9em2Ygch/Tnfrsf9em2Ygch
(NOD/ShiLtDvs-Tnfrsf9em2Ygch)
abnormal T cell physiology J:208927
immune system phenotype J:208927
insulitis J:208927
Tnfrsf9m1Btlr/Tnfrsf9m1Btlr
(C57BL/6J-Tnfrsf9m1Btlr)
decreased CD8-positive, alpha-beta T cell number J:265260
decreased CD8-positive, naive alpha-beta T cell number J:265260
decreased single-positive T cell number J:265260
increased B cell number J:265260
increased effector memory CD4-positive, alpha-beta T cell number J:265260
increased effector memory CD8-positive, alpha-beta T cell number J:265260
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
(B6.Cg-Tnfrsf9tm1Byk)
abnormal cytotoxic T cell physiology J:83996
decreased IgG2a level J:83996
decreased IgG3 level J:83996
decreased interferon-gamma secretion J:83996
decreased interleukin-2 secretion J:83996
decreased interleukin-4 secretion J:83996
increased T cell proliferation J:83996
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
(C.Cg-Tnfrsf9tm1Byk)
abnormal cytotoxic T cell physiology J:83722
abnormal immunoglobulin level J:83996
decreased IgG2a level J:83996
decreased IgG3 level J:83996
decreased interferon-gamma secretion J:83996
decreased interleukin-2 secretion J:83996
decreased interleukin-4 secretion J:83996
decreased interleukin-12 secretion J:83722
increased IgA level J:83722
increased IgG2a level J:83722
increased IgG2b level J:83722
increased splenocyte proliferation J:83722
increased T cell proliferation J:83996
Tnfrsf9tm1Lpc/Tnfrsf9tm1Lpc
(B6.129-Tnfrsf9tm1Lpc)
abnormal memory T cell physiology J:145439
immune system phenotype J:145439
Tnfrsf10btm1Wnt/Tnfrsf10btm1Wnt
(involves: 129S6/SvEvTac * C57BL/6)
abnormal innate immunity J:94681
abnormal interferon level J:94681
decreased susceptibility to Herpesvirales infection J:94681
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:94681
increased circulating interferon-gamma level J:94681
increased circulating interleukin-12b level J:94681
increased interleukin-12 secretion J:94681
increased NK cell number J:94681
increased tumor necrosis factor secretion J:94681
Tnfrsf10btm1Wsed/Tnfrsf10btm1Wsed
(involves: 129P2/OlaHsd)
enlarged thymus J:96816
Tnfrsf11adel8/Tnfrsf11adel8
(involves: 129)
abnormal mesenteric lymph node morphology J:111512
decreased osteoclast cell number J:111512
enlarged spleen J:111512
Tnfrsf11atm1.1Pngr/Tnfrsf11atm1.2Pngr
Tg(Gfap-cre)2Brn/0

(involves: 129 * C57BL/6 * C57BL/6NTac * FVB/N)
decreased susceptibility to endotoxin shock J:155398
Tnfrsf11atm1.1Pngr/Tnfrsf11atm1.2Pngr
Tg(Nes-cre)1Kln/0

(involves: 129 * C57BL/6 * C57BL/6NTac * SJL)
decreased susceptibility to endotoxin shock J:155398
Tnfrsf11atm1.1Sral/Tnfrsf11a+
(B6.129P2(Cg)-Tnfrsf11atm1.1Sral)
abnormal osteoclast differentiation J:312215
abnormal osteoclast physiology J:312215
increased osteoclast cell number J:312215
Tnfrsf11atm1.1Sral/Tnfrsf11atm1.1Sral
(B6.129P2(Cg)-Tnfrsf11atm1.1Sral)
abnormal osteoclast differentiation J:312215
decreased osteoclast cell number J:312215
Tnfrsf11atm1.2Pngr/Tnfrsf11atm1.2Pngr
(B6.Cg-Tnfrsf11atm1.2Pngr)
absent lymph nodes J:155398
decreased osteoclast cell number J:155398
Tnfrsf11atm1Imx/Tnfrsf11atm1Imx
(involves: 129 * C57BL/6)
abnormal osteoclast differentiation J:57899
absent lymph nodes J:57899
decreased B cell number J:57899
decreased mature B cell number J:57899
decreased osteoclast cell number J:57899
decreased Peyer's patch number J:57899
decreased spleen germinal center size J:57899
increased granulocyte number J:57899
increased neutrophil cell number J:57899
small Peyer's patches J:57899
spleen hyperplasia J:57899
Tnfrsf11atm1Imx/Tnfrsf11atm1Imx
(involves: 129)
abnormal negative T cell selection J:125864
abnormal thymus epithelium morphology J:125864
Tnfrsf11atm1Kost/Tnfrsf11atm1Kost
(involves: 129/Sv * Black Swiss)
abnormal osteoclast morphology J:166279
Tnfrsf11bem1(IMPC)Mbp/Tnfrsf11bem1(IMPC)Mbp
(C57BL/6N-Tnfrsf11bem1(IMPC)Mbp/MbpMmucd)
small spleen J:211773
Tnfrsf11btm1Eac/Tnfrsf11btm1Eac
(involves: 129S4/SvJaeSor)
abnormal dendritic cell antigen presentation J:67105
abnormal immune system morphology J:67105
abnormal immune system physiology J:67105
abnormal immunoglobulin level J:67105
abnormal pro-B cell differentiation J:67105
increased B cell number J:67105
increased immature B cell number J:67105
increased pro-B cell number J:67105
Tnfrsf11btm1Khs/Tnfrsf11btm1Khs
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:111153, J:48325
abnormal osteoclast physiology J:111153
increased osteoclast cell number J:80503
Tnfrsf11btm1Wss/Tnfrsf11btm1Wss
(either: (involves: 129X1/SvJ * C57BL/6) or (involves: 129X1/SvJ * Black Swiss))
abnormal osteoclast morphology J:47602
Tnfrsf12atm1Biib/Tnfrsf12atm1Biib
(B6.129S4-Tnfrsf12atm1Biib)
abnormal chemokine secretion J:126416
Tnfrsf13btm1Cmac/Tnfrsf13btm1Cmac
(Not Specified)
enlarged spleen J:91914
immune system phenotype J:92334
increased B cell number J:91914
Tnfrsf13btm1Rjb/Tnfrsf13btm1Rjb
(involves: 129X1/SvJ * C57BL/6)
abnormal B cell activation J:69474
decreased IgA level J:69474
decreased IgM level J:69474
increased B cell number J:69474
increased B cell proliferation J:69474
increased spleen weight J:69474
Tnfrsf13btm1Rjb/Tnfrsf13btm1Rjb
(involves: 129X1/SvJ)
abnormal class switch recombination J:95288
decreased IgA level J:95288
decreased IgE level J:95288
decreased IgG1 level J:95288
Tnfrsf13btm1Vmd/Tnfrsf13btm1Vmd
(involves: C57BL/6)
abnormal immunoglobulin level J:70172
abnormal lymph node primary follicle morphology J:70172, J:82331
abnormal Peyer's patch follicle morphology J:70172
abnormal spleen morphology J:70172
abnormal spleen periarteriolar lymphoid sheath morphology J:70172, J:82331
abnormal spleen primary B follicle morphology J:70172
enlarged lymph nodes J:70172, J:82331
enlarged spleen J:70172, J:82331
glomerulonephritis J:82331
increased anti-double stranded DNA antibody level J:82331
increased anti-nuclear antigen antibody level J:82331
increased B cell number J:70172, J:82331
increased B cell proliferation J:70172
increased follicular B cell number J:70172
increased IgG1 level J:70172
increased marginal zone B cell number J:70172
increased mature B cell number J:70172
increased spleen germinal center size J:70172
increased spleen white pulp amount J:70172
increased transitional stage B cell number J:70172
kidney inflammation J:82331
liver inflammation J:82331
Tnfrsf13cBcmd1/Tnfrsf13cBcmd1
(A/WySnJ)
abnormal lymphocyte physiology J:92334
decreased B cell proliferation J:122315
decreased IgG level J:122315
decreased interferon-gamma secretion J:92334
decreased T cell proliferation J:92334
increased length of allograft survival J:92334
Tnfrsf13cm1Btlr/Tnfrsf13cm1Btlr
(C57BL/6J-Tnfrsf13cm1Btlr)
decreased B cell number J:265247
Tnfrsf13cM2Btlr/Tnfrsf13cM2Btlr
(C57BL/6J-Tnfrsf13cM2Btlr)
decreased B cell number J:265247
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass
(C57BL/6-Tnfrsf13ctm1Mass)
abnormal B cell physiology J:113556
absent marginal zone B cells J:92732
arrested B cell differentiation J:92732
decreased B-2 B cell number J:92732
decreased IgG1 level J:92732
decreased IgG2a level J:92732
decreased IgG2b level J:92732
decreased IgG3 level J:92732
decreased IgG level J:92732
decreased IgM level J:92732
decreased mature B cell number J:92732
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass
(involves: C57BL/6)
decreased lymphocyte cell number J:139293
decreased mature B cell number J:139293
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass
Tg(BCL2)22Wehi/0

(involves: C57BL/6 * SJL)
immune system phenotype J:92732
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass
Traf2tm1Rbr/Traf2tm1Rbr

(involves: C57BL/6)
decreased germinal center B cell number J:172843
decreased spleen germinal center size J:172843
immune system phenotype J:172843
Tnfrsf13ctm1Mass/Tnfrsf13ctm1Mass
Traf3tm1Rbr/Traf3tm1Rbr

(involves: C57BL/6)
immune system phenotype J:172843
Tnfrsf13ctm1Msc/Tnfrsf13ctm1Msc
(involves: 129P2/OlaHsd * C57BL/6)
abnormal humoral immune response J:92676
absent marginal zone B cells J:92676
absent transitional stage B cells J:92676
decreased B cell number J:92676
decreased B-2 B cell number J:92676
decreased IgD level J:92676
decreased IgG1 level J:92676
decreased IgG level J:92676
decreased IgM level J:92676
Tnfrsf14tm1Csj/Tnfrsf14tm1Csj
(B6.Cg-Tnfrsf14tm1Csj)
decreased interferon-gamma secretion J:169369
decreased interleukin-6 secretion J:169369
decreased interleukin-10 secretion J:169369
decreased susceptibility to induced colitis J:169369
decreased tumor necrosis factor secretion J:169369
Tnfrsf14tm1Kpf/Tnfrsf14tm1Kpf
(B6.129P2-Tnfrsf14tm1Kpf)
abnormal T cell physiology J:99456
increased T cell proliferation J:99456
Tnfrsf14tm1Kro/Tnfrsf14tm1Kro
(C57BL/6-Tnfrsf14tm1Kro)
decreased susceptibility to Herpesvirales infection J:243038
Tnfrsf14tm1Wwhk/Tnfrsf14tm1Wwhk
(B6.Cg-Tnfrsf14tm1Wwhk)
decreased length of allograft survival J:119356
Tnfrsf17tm1Kplm/Tnfrsf17tm1Kplm
(involves: 129P2/OlaHsd * C57BL/6)
decreased plasma cell number J:124543
Tnfrsf18tm1Ppp/Tnfrsf18tm1Ppp
(involves: 129/Sv * C57BL/6)
abnormal T cell activation J:77393
immune system phenotype J:77393
increased interleukin-2 secretion J:77393
increased T cell apoptosis J:77393
increased T cell proliferation J:77393
Tnfrsf21tm1Ddy/Tnfrsf21tm1Ddy
(involves: 129S1/Sv * 129X1/SvJ)
abnormal T-helper 1 physiology J:70594
abnormal T-helper 2 physiology J:70594
increased B cell proliferation J:109341
increased IgG1 level J:109341
increased IgG2a level J:109341
increased IgG2b level J:109341
increased IgG3 level J:109341
increased IgM level J:109341
increased interleukin-4 secretion J:70594
increased interleukin-5 secretion J:70594
increased interleukin-10 secretion J:70594
increased interleukin-13 secretion J:70594
increased spleen germinal center size J:109341
increased T cell proliferation J:70594
Tnfrsf21tm1Vmd/Tnfrsf21tm1Vmd
(involves: C57BL/6)
abnormal cell-mediated immunity J:72761
abnormal T-helper 2 physiology J:72761
immune system phenotype J:72761
increased CD4-positive, alpha-beta T cell number J:72761
increased CD8-positive, alpha-beta T cell number J:72761
increased IgE level J:72761
increased IgG1 level J:72761
increased IgG2a level J:72761
increased IgM level J:72761
increased interferon-gamma secretion J:72761
increased interleukin-2 secretion J:72761
increased interleukin-4 secretion J:72761
increased T cell number J:72761
increased T cell proliferation J:72761
Tnfrsf25tm1Mjo/Tnfrsf25tm1Mjo
(involves: 129P2/OlaHsd)
abnormal negative T cell selection J:84536
decreased T cell apoptosis J:84536
enlarged thymus J:84536
increased thymocyte number J:84536
Tnfsf4tm1Shr/Tnfsf4tm1Shr
(involves: 129S4/SvJae)
abnormal cell-mediated immunity J:59203
abnormal dendritic cell antigen presentation J:59203
decreased interferon-gamma secretion J:59203
decreased interleukin-2 secretion J:59203
decreased interleukin-4 secretion J:59203
decreased susceptibility to type IV hypersensitivity reaction J:59203
decreased T cell proliferation J:59203
immune system phenotype J:59203
Tnfsf4tm1Shr/Tnfsf4tm1Shr
(NOD.129S4-Tnfsf4tm1Shr)
decreased susceptibility to autoimmune diabetes J:86926
Tnfsf4tm1Shr/Tnfsf4tm1Shr
(C.129S4-Tnfsf4tm1Shr)
abnormal cytokine secretion J:59203
abnormal dendritic cell antigen presentation J:59203
Tnfsf4tm1Sug/Tnfsf4tm1Sug
(B6.129S4-Tnfsf4tm1Sug)
abnormal cytokine secretion J:80214
decreased susceptibility to type IV hypersensitivity reaction J:80214
decreased T cell proliferation J:80214
Tnfsf8tm1Pod/Tnfsf8tm1Pod
(B6.129X1-Tnfsf8tm1Pod)
decreased susceptibility to graft versus host disease J:92723
Tnfsf9tm1Thw/Tnfsf9tm1Thw
(involves: 129 * C57BL/6)
abnormal cytotoxic T cell physiology J:76373
immune system phenotype J:76373
Tnfsf10tm1Mjs/Tnfsf10tm1Mjs
(C.129-Tnfsf10tm1Mjs)
abnormal negative T cell selection J:82145
decreased susceptibility to bacterial infection J:87620
decreased susceptibility to bacterial infection induced morbidity/mortality J:87620
immune system phenotype J:84838
impaired natural killer cell mediated cytotoxicity J:73948
liver inflammation J:87620
thymus hyperplasia J:84838, J:82145
Tnfsf10tm1Mjs/Tnfsf10tm1Mjs
(B6.129-Tnfsf10tm1Mjs)
abnormal negative T cell selection J:82145
immune system phenotype J:84838
increased IgG1 level J:82145
increased IgG2a level J:82145
increased interferon-gamma secretion J:82145
increased interleukin-2 secretion J:82145
increased susceptibility to autoimmune diabetes J:82145
increased susceptibility to experimental autoimmune encephalomyelitis J:101672
increased susceptibility to induced arthritis J:82145
thymus hyperplasia J:82145
Tnfsf10tm1Sdg/Tnfsf10tm1Sdg
(B6.129-Tnfsf10tm1Sdg)
immune system phenotype J:79085
Tnfsf10tm1Sdg/Tnfsf10tm1Sdg
(involves: 129 * C57BL/6)
immune system phenotype J:79085
Tnfsf11tles/Tnfsf11tles
(involves: 129S6/SvEvTac * C57BL/6J)
absent lymph nodes J:179743
decreased osteoclast cell number J:179743
enlarged spleen J:179743
thymus hypoplasia J:179743
Tnfsf11tles/Tnfsf11tm1Pngr
(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J)
decreased osteoclast cell number J:179743
Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob
Tg(Dmp1-cre)1Jqfe/0

(involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB)
abnormal osteoclast cell number J:177558
decreased osteoclast cell number J:177558
Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob
Tg(Prrx1-cre)1Cjt/0

(involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6)
decreased osteoclast cell number J:177558
Tnfsf11tm1.1Htaka/Tnfsf11tm1.2Htaka
Tg(Dmp1-cre)1Jqfe/0

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * FVB/N)
decreased osteoclast cell number J:177557
Tnfsf11tm1.2Htaka/Tnfsf11+
(B6.Cg-Tnfsf11tm1.2Htaka)
decreased osteoclast cell number J:177557
Tnfsf11tm1.2Htaka/Tnfsf11tm1.2Htaka
(B6.Cg-Tnfsf11tm1.2Htaka)
decreased osteoclast cell number J:177557
increased spleen weight J:177557
Tnfsf11tm1Pngr/Tnfsf11tm1Pngr
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune system morphology J:52369
abnormal immune system physiology J:52369
abnormal pro-B cell differentiation J:52369
absent mesenteric lymph nodes J:52369
absent peripheral lymph nodes J:52369
arrested T cell differentiation J:52369
decreased immature B cell number J:52369
decreased interferon-gamma secretion J:52369
decreased interleukin-2 secretion J:52369
decreased interleukin-4 secretion J:52369
decreased interleukin-5 secretion J:52369
decreased interleukin-6 secretion J:52369
decreased mature B cell number J:52369
decreased osteoclast cell number J:52369
decreased thymus weight J:52369
immune system phenotype J:52369
increased spleen weight J:52369
small Peyer's patches J:52369
thymus hypoplasia J:52369
Tnfsf11tm1Pngr/Tnfsf11tm1Pngr
(involves: 129P2/OlaHsd)
abnormal thymus epithelium morphology J:173115
Tnfsf11tm1Ywc/Tnfsf11+
(involves: 129P2/OlaHsd)
absent peripheral lymph nodes J:65888
Tnfsf11tm1Ywc/Tnfsf11tm1Ywc
(involves: 129P2/OlaHsd)
abnormal cervical lymph node morphology J:65888
abnormal spleen B cell follicle morphology J:65888
abnormal spleen marginal zone morphology J:65888
abnormal spleen morphology J:65888
abnormal splenic cell ratio J:233265
abnormal thymus cell ratio J:233265
absent cervical lymph nodes J:65888
absent mesenteric lymph nodes J:65888
absent peripheral lymph nodes J:65888
decreased Langerhans cell number J:137471
decreased osteoclast cell number J:65888, J:64737
decreased Peyer's patch number J:233265
decreased spleen white pulp amount J:233265
increased spleen red pulp amount J:233265
small Peyer's patches J:233265
small thymus medulla J:233265
Tnfsf12tm1Ash/Tnfsf12tm1Ash
(B6.129-Tnfsf12tm1Ash)
abnormal cytokine secretion J:104801
abnormal immune system organ morphology J:104801
abnormal leukocyte morphology J:104801
decreased interleukin-10 secretion J:104801
enlarged lymph nodes J:104801
enlarged spleen J:104801
increased double-positive T cell number J:104801
increased interferon-gamma secretion J:104801
increased interleukin-12 secretion J:104801
increased memory T cell number J:104801
increased NK cell number J:104801
increased susceptibility to bacterial infection J:104801
increased T-helper 1 cell number J:104801
Tnfsf13tm1Geha/Tnfsf13tm1Geha
(involves: 129S4/SvJae)
abnormal class switch recombination J:88910
decreased IgA level J:88910
decreased IgM level J:88910
immune system phenotype J:88910
increased IgG level J:88910
increased memory T cell number J:88910
increased spleen germinal center number J:88910
increased spleen germinal center size J:88910
Tnfsf13tm1Pod/Tnfsf13+
(B6.Cg-Tnfsf13tm1Pod)
decreased IgA level J:141374
Tnfsf13tm1Pod/Tnfsf13tm1Pod
(B6.Cg-Tnfsf13tm1Pod)
abnormal interleukin secretion J:141374
decreased IgA level J:141374
decreased IgG2a level J:141374
decreased interleukin-10 secretion J:141374
decreased interleukin-17 secretion J:141374
decreased susceptibility to induced arthritis J:141374
increased IgG1 level J:141374
increased interferon-gamma secretion J:141374
increased interleukin-4 secretion J:141374
increased interleukin-5 secretion J:141374
increased interleukin-13 secretion J:141374
increased interleukin-17 secretion J:141374
increased T cell proliferation J:141374
Tnfsf13bm1Anu/Tnfsf13bm1Anu
(C57BL/6JAnu-Tnfsf13bm1Anu/AnuApb)
abnormal B cell differentiation J:104190
decreased mature B cell number J:104190
increased immature B cell number J:104190
Tnfsf13bM1Btlr/Tnfsf13b+
(C57BL/6J-Tnfsf13bM1Btlr)
decreased B cell number J:220069
decreased IgG level J:220069
decreased IgM level J:220069
impaired humoral immune response J:220069
increased single-positive T cell number J:220069
increased T cell number J:220069
Tnfsf13bM1Btlr/Tnfsf13bM1Btlr
(C57BL/6J-Tnfsf13bM1Btlr)
decreased B cell number J:220069
decreased IgG level J:220069
decreased IgM level J:220069
impaired humoral immune response J:220069
increased single-positive T cell number J:220069
increased T cell number J:220069
Tnfsf13bm2Btlr/Tnfsf13bm2Btlr
(C57BL/6J-Tnfsf13bm2Btlr)
decreased B cell number J:220070
decreased IgG level J:220070
impaired humoral immune response J:220070
Tnfsf13bm3Btlr/Tnfsf13bm3Btlr
(C57BL/6J-Tnfsf13bm3Btlr)
abnormal lymphocyte morphology J:272850
decreased B cell number J:272850
Tnfsf13btm1Cleg/Tnfsf13btm1Cleg
(involves: 129S5/SvEvBrd)
abnormal B cell differentiation J:71301
abnormal B cell physiology J:71301
abnormal leukocyte morphology J:71301
abnormal lymph organ size J:71301
decreased follicular B cell number J:71301
decreased IgG level J:71301
decreased IgM level J:71301
decreased mature B cell number J:71301
decreased memory T cell number J:71301
increased T cell number J:71301
lymph node hypoplasia J:71301
spleen hypoplasia J:71301
Tnfsf13btm1Msc/Tnfsf13b+
(involves: 129S2/SvPas * C57BL/6)
decreased immunoglobulin level J:71681
Tnfsf13btm1Msc/Tnfsf13btm1Msc
(involves: 129S2/SvPas * C57BL/6)
abnormal B cell differentiation J:71681
abnormal humoral immune response J:71681
abnormal lymph node B cell domain morphology J:71681
arrested B cell differentiation J:71681
decreased B cell number J:71681
decreased follicular B cell number J:71681
decreased immunoglobulin level J:71681
decreased marginal zone B cell number J:71681
decreased spleen weight J:71681
Tnfsf13btm1Msc/Tnfsf13btm1Msc
(involves: 129S2/SvPas)
decreased B cell number J:138560
decreased follicular B cell number J:138560
decreased T cell proliferation J:92334
decreased transitional stage B cell number J:138560
increased length of allograft survival J:92334
Tnfsf13btm1Msc/Tnfsf13btm1Msc
Traf2tm1Rbr/Traf2tm1Rbr

(involves: 129S2/SvPas * C57BL/6)
absent follicular B cells J:132877
absent marginal zone B cells J:132877
decreased mature B cell number J:132877
Tnfsf14tm1Ddy/Tnfsf14tm1Ddy
(involves: 129S1/Sv * 129X1/SvJ)
abnormal cytotoxic T cell physiology J:84366
abnormal T cell activation J:84366
decreased T cell proliferation J:84366
immune system phenotype J:84366
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell subpopulation ratio J:77250
decreased cytotoxic T cell cytolysis J:77250
decreased interferon-gamma secretion J:77250
decreased interleukin-2 secretion J:77250
decreased interleukin-4 secretion J:77250
decreased interleukin-10 secretion J:77250
decreased splenocyte proliferation J:77250
decreased T cell proliferation J:77250
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
(involves: 129P2/OlaHsd)
abnormal gamma-delta T cell morphology J:169863
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
(B6.129P2-Tnfsf14tm1Kpf)
abnormal osteoclast differentiation J:294030
Tnfsf14tm1Lpc/Tnfsf14tm1Lpc
(involves: 129X1/SvJ * C57BL/6)
abnormal cytotoxic T cell physiology J:76414
decreased cytotoxic T cell cytolysis J:76414
decreased inflammatory response J:107803
decreased interferon-gamma secretion J:76414
decreased tumor necrosis factor secretion J:76414
Tnfsf14tm1Lpc/Tnfsf14tm1Lpc
(B6.129X1-Tnfsf14tm1Lpc)
immune system phenotype J:158663
Tnfsf14tm1Wwh/Tnfsf14tm1Wwh
(involves: 129 * C57BL/6)
increased length of allograft survival J:75705
Tnfsf15tm1Cdon/Tnfsf15tm1Cdon
(B6.129-Tnfsf15tm1Cdon)
abnormal dendritic cell differentiation J:136280
decreased susceptibility to experimental autoimmune encephalomyelitis J:136280
Tnfsf15tm1Hluo/Tnfsf15tm1Hluo
(D1LacJ.129(B6)-Tnfsf15tm1Hluo)
decreased B cell number J:207029
decreased germinal center B cell number J:207029
decreased IgG2a level J:207029
decreased IgG2b level J:207029
decreased IgG level J:207029
decreased plasma cell number J:207029
decreased susceptibility to induced arthritis J:207029
decreased T cell number J:207029
decreased T follicular helper cell number J:207029
immune system phenotype J:207029
lymph node hypoplasia J:207029
Tnfsf15tm1Lex/Tnfsf15tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
increased NK cell number J:82809
Tnikm1Anu/Tnikm1Anu
(C57BL/6NCrlAnu-Tnikm1Anu/Anu)
immune system phenotype J:104190
Tnip1Gt(E059E05)Wrst/Tnip1Gt(E059E05)Wrst
(involves: 129P2/OlaHsd * C57BL/6)
decreased interleukin-12 secretion J:180054
decreased interleukin-12b secretion J:180054
enlarged lymph nodes J:180054
enlarged spleen J:180054
glomerulonephritis J:180054
increased anti-double stranded DNA antibody level J:180054
increased anti-nuclear antigen antibody level J:180054
increased IgA level J:180054
increased IgG1 level J:180054
increased IgG2b level J:180054
increased IgM level J:180054
increased neutrophil cell number J:180054
increased susceptibility to systemic lupus erythematosus J:180054
lymph node hyperplasia J:180054
spleen hyperplasia J:180054
Tnip1m1Btlr/Tnip1m1Btlr
(C57BL/6J-Tnip1m1Btlr)
decreased B cell number J:265175
decreased B-2 B cell number J:265175
increased anti-double stranded DNA antibody level J:265175
increased B-1a cell number J:265175
increased B-1b cell number J:265175
increased dendritic cell number J:265175
increased IgA level J:265175
increased IgE level J:265175
increased macrophage cell number J:265175
increased susceptibility to induced colitis J:265175
Tnip1tm1.1Pcoh/Tnip1+
(involves: 129P2/OlaHsd * C57BL/6)
increased anti-double stranded DNA antibody level J:176826
Tnip1tm1.1Pcoh/Tnip1tm1.1Pcoh
(involves: 129P2/OlaHsd * C57BL/6)
abnormal complement pathway J:176826
abnormal effector T cell morphology J:176826
abnormal immune system morphology J:176826
abnormal Peyer's patch morphology J:176826
abnormal plasma cell morphology J:176826
abnormal spleen germinal center morphology J:176826
enlarged lymph nodes J:176826
enlarged spleen J:176826
glomerulonephritis J:176826
immune system phenotype J:176826
increased anti-double stranded DNA antibody level J:176826
increased anti-nuclear antigen antibody level J:176826
increased B cell number J:176826
increased B cell proliferation J:176826
increased germinal center B cell number J:176826
increased granulocyte number J:176826
increased IgA level J:176826
increased IgE level J:176826
increased IgG1 level J:176826
increased IgG2a level J:176826
increased IgG2b level J:176826
increased IgG3 level J:176826
increased IgG level J:176826
increased IgM level J:176826
increased immunoglobulin level J:176826
increased interleukin-6 secretion J:176826
increased interleukin-12b secretion J:176826
increased monocyte cell number J:176826
increased plasma cell number J:176826
increased spleen red pulp amount J:176826
increased spleen weight J:176826
increased spleen white pulp amount J:176826
increased T follicular helper cell number J:176826
increased tumor necrosis factor secretion J:176826
Tnip1tm1.2Ama/Tnip1tm1.2Ama
Tg(Itgax-cre)1-1Reiz/0

(involves: C57BL/6 * C57BL/6J * CBA)
abnormal leukocyte morphology J:205446
enlarged lymph nodes J:205446
enlarged spleen J:205446
increased interleukin-6 secretion J:205446
increased interleukin-12 secretion J:205446
increased interleukin-23 secretion J:205446
increased memory T cell number J:205446
increased plasmacytoid dendritic cell number J:205446
increased tumor necrosis factor secretion J:205446
Tnip1tm1.2Pcoh/Tnip1tm1.2Pcoh
(involves: 129P2/OlaHsd * C57BL/6)
abnormal immune system morphology J:176826
Tnip1tm1b(EUCOMM)Hmgu/Tnip1tm1b(EUCOMM)Hmgu
(C57BL/6N-Tnip1tm1b(EUCOMM)Hmgu/H)
decreased lymphocyte cell number J:211773
increased basophil cell number J:211773
increased large unstained cell number J:211773
increased monocyte cell number J:211773
increased spleen weight J:211773
Tnip2tm1.1Sley/Tnip2tm1.1Sley
(involves: 129S4/SvJae * 129S8/SvEv * C57BL/6)
abnormal macrophage physiology J:112395
immune system phenotype J:112395
Tnip3tm1Rds/Tnip3tm1Rds
(involves: 129S6/SvEvTac)
immune system phenotype J:122758
Tnk2em1(IMPC)Tcp/Tnk2em1(IMPC)Tcp
(C57BL/6N-Tnk2em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Tnnem1(IMPC)Mbp/Tnnem1(IMPC)Mbp
(C57BL/6NCrl-Tnnem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tnrem1(IMPC)Rbrc/Tnrem1(IMPC)Rbrc
(C57BL/6NJcl-Tnrem1(IMPC)Rbrc/Rbrc)
increased spleen weight J:211773
Tns1tm1Efu/Tns1tm1Efu
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
tubulointerstitial nephritis J:39202
Tns2nph/Tns2nph
(involves: ICR)
enlarged lymph nodes J:24698
glomerulonephritis J:108691
Tns3Gt(XK294)Byg/Tns3Gt(XK294)Byg
(involves: 129P2/OlaHsd * C57BL/6)
small spleen J:96666
Tnxbtm1b(EUCOMM)Hmgu/Tnxbtm1b(EUCOMM)Hmgu
(C57BL/6N-Tnxbtm1b(EUCOMM)Hmgu/H)
enlarged spleen J:211773
Tob2tm1Tya/Tob2tm1Tya
(involves: 129S4/SvJae * C57BL/6)
abnormal osteoclast differentiation J:134287
abnormal osteoclast physiology J:134287
increased osteoclast cell number J:134287
Tolliptm1Kbns/Tolliptm1Kbns
(involves: C57BL/6)
decreased circulating interleukin-6 level J:105514
decreased interleukin-6 secretion J:105514
decreased tumor necrosis factor secretion J:105514
Tom1l2Gt(XG909)Byg/Tom1l2+
(involves: 129P2/OlaHsd * C57BL/6J)
enlarged spleen J:133892
increased susceptibility to infection J:133892
Tom1l2Gt(XG909)Byg/Tom1l2Gt(XG909)Byg
(involves: 129P2/OlaHsd * C57BL/6J)
abnormal humoral immune response J:133892
abnormal immune system physiology J:133892
abnormal inflammatory response J:133892
abnormal lymph node cell ratio J:133892
abnormal spleen B cell follicle morphology J:133892
abnormal spleen morphology J:133892
abnormal spleen periarteriolar lymphoid sheath morphology J:133892
abnormal splenic cell ratio J:133892
conjunctivitis J:133892
dermatitis J:133892
enlarged spleen J:133892
increased B cell number J:133892
increased CD4-positive, alpha-beta T cell number J:133892
increased CD8-positive, alpha-beta T cell number J:133892
increased inflammatory response J:133892
increased leukocyte cell number J:133892
increased spleen white pulp amount J:133892
increased susceptibility to bacterial infection J:133892
increased susceptibility to infection J:133892
increased T cell number J:133892
lymphoid hyperplasia J:133892
Tomm5Gt(OST44663)Lex/Tomm5Gt(OST44663)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
increased eosinophil cell number J:186382
lung inflammation J:186382
thymus atrophy J:186382
Tomm6tm1a(KOMP)Wtsi/Tomm6+
(C57BL/6N-Tomm6tm1a(KOMP)Wtsi/Wtsi)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Tomm20em1(IMPC)J/Tomm20+
(C57BL/6NJ-Tomm20em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Top2aem2(IMPC)Tcp/Top2a+
(C57BL/6NCrl-Top2aem2(IMPC)Tcp/Tcp)
small spleen J:211773
small thymus J:211773
Top2bem1(IMPC)Mbp/Top2b+
(C57BL/6NCrl-Top2bem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Top3btm1Jcw/Top3btm1Jcw
(involves: 129S6/SvEvTac * C57BL/6)
dermatitis J:69405
enlarged axillary lymph nodes J:69405
enlarged spleen J:69405
enlarged submandibular lymph nodes J:69405
glomerulonephritis J:69405
increased inflammatory response J:69405
pancreas inflammation J:69405
stomach inflammation J:69405
Toxtm1.1Kay/Toxtm1.1Kay
(involves: 129S6/SvEvTac)
abnormal CD4-positive T cell differentiation J:131287
abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology J:131287
abnormal CD8-positive, alpha beta T cell morphology J:131287
decreased CD4-positive, alpha-beta T cell number J:131287
decreased cytotoxic T cell cytolysis J:131287
decreased NK T cell number J:131287
Toxtm1.1Kay/Toxtm1.1Kay
(involves: 129S6/SvEvTac * C57BL/6)
abnormal positive T cell selection J:164687
abnormal spleen morphology J:164687
absent axillary lymph nodes J:164687
absent inguinal lymph nodes J:164687
absent mesenteric lymph nodes J:164687
absent popliteal lymph nodes J:164687
decreased NK cell number J:164687
decreased Peyer's patch number J:164687
small Peyer's patches J:164687
Toxtm1b(KOMP)Wtsi/Toxtm1b(KOMP)Wtsi
(C57BL/6N-Toxtm1b(KOMP)Wtsi/Tcp)
increased spleen weight J:211773
Toxtm1Kay/Toxtm1Kay
Tg(Lck-cre)1Cwi/0

(involves: 129S6/SvEvTac * C57BL/6)
abnormal CD4-positive T cell differentiation J:164687
Tpcn1tm1.1Dren/Tpcn1tm1.1Dren
Tpcn2tm1.1Dren/Tpcn2tm1.1Dren

(Not Specified)
abnormal macrophage physiology J:189070
Tpcn2tm1b(EUCOMM)Hmgu/Tpcn2tm1b(EUCOMM)Hmgu
(C57BL/6N-Tpcn2tm1b(EUCOMM)Hmgu/H)
increased eosinophil cell number J:211773
Tph2em1(IMPC)Mbp/Tph2+
(C57BL/6N-Tph2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tph2em1(IMPC)Mbp/Tph2em1(IMPC)Mbp
(C57BL/6N-Tph2em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
increased eosinophil cell number J:211773
Tpi1a-m6Neu/Tpi1a-m6Neu
(involves: 101/El * C3H/El)
increased spleen weight J:163223
Tpi1rbc19/Tpi1rbc19
(SJL-Tpi1rbc19)
abnormal spleen red pulp morphology J:263104
enlarged spleen J:263104
Tpoem1(IMPC)H/Tpoem1(IMPC)H
(C57BL/6NTac-Tpoem1(IMPC)H/H)
decreased spleen weight J:211773
TpoR479C/TpoR479C
(involves: ICR)
small spleen J:112930
Tpp2Gt(OST432061)Lex/Tpp2Gt(OST432061)Lex
(B6.129S5-Tpp2Gt(OST432061)Lex)
abnormal level of surface class I molecules J:157195
Tpp2Gt(OST432061)Lex/Tpp2Gt(OST432061)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal antigen presentation J:157195
Tpp2tm1.1Gnie/Tpp2tm1.1Gnie
(involves: 129S6/SvEvTac * C57BL/6)
abnormal cytotoxic T cell physiology J:133572
abnormal immune system cell morphology J:133572
abnormal immune system organ morphology J:133572
abnormal spleen morphology J:133572
abnormal splenic cell ratio J:133572
decreased CD8-positive, alpha-beta T cell number J:133572
decreased double-positive T cell number J:133572
decreased T cell number J:133572
enlarged spleen J:133572
increased double-negative T cell number J:133572
increased single-positive T cell number J:133572
increased spleen red pulp amount J:133572
increased T cell apoptosis J:133572
increased T cell number J:133572
thymus atrophy J:133572
Tpp2tm1.1Gnie/Tpp2tm1.1Gnie
(involves: 129S6/SvEvTac)
abnormal CD4-positive T cell differentiation J:221205
abnormal CD8-positive, alpha-beta T cell differentiation J:221205
abnormal lymphocyte physiology J:221205
decreased leukocyte cell number J:221205
enlarged lymph nodes J:221205
enlarged spleen J:221205
increased anti-nuclear antigen antibody level J:221205
increased autoantibody level J:221205
increased B cell number J:221205
increased memory T cell number J:221205
Tppp3em1(IMPC)Ccpcz/Tppp3+
(C57BL/6NCrl-Tppp3em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased CD4-positive NK T cell number J:211773
increased memory-marker CD4-positive NK T cell number J:211773
Tpsab1m1/Tpsab1m1
(involves: C57BL/6J)
abnormal mast cell differentiation J:142880
Tpsab1m1/Tpsab1m1
Tpsb2tm1(cre)Adch/Tpsb2tm1(cre)Adch

(B6.Cg-Tpsb2tm1(cre)Adch Tpsab1m1)
abnormal mast cell differentiation J:142880
decreased susceptibility to induced arthritis J:142880
Tpsb2tm1(cre)Adch/Tpsb2tm1(cre)Adch
(B6.Cg-Tpsb2tm1(cre)Adch)
increased susceptibility to bacterial infection J:124554
Tpsb2tm1.1Mfg/Tpsb2tm1.1Mfg
(B6.129-Tpsb2tm1.1Mfg)
abnormal mast cell differentiation J:142880
decreased susceptibility to induced arthritis J:142880
impaired eosinophil recruitment J:133373
impaired neutrophil chemotaxis J:142880
increased susceptibility to parasitic infection J:133373
Tpsg1tm1.2Rls/Tpsg1tm1.2Rls
(involves: C57BL/6 * C57BL/6NTac)
decreased susceptibility to colitis induced morbidity/mortality J:243813
immune system phenotype J:243813
Tpx2Gt(D028B03)Wrst/Tpx2+
(involves: 129S2/SvPas * C57BL/6J)
abnormal splenocyte morphology J:184948
granulomatous inflammation J:184948
Tra2atm2b(EUCOMM)Hmgu/Tra2a+
(C57BL/6N-Tra2atm2b(EUCOMM)Hmgu/Bay)
increased basophil cell number J:211773
Trabd2bem2(IMPC)Ccpcz/Trabd2bem2(IMPC)Ccpcz
(C57BL/6N-Trabd2bem2(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Traddtm1.1Mak/Tradd+
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N))
decreased acute inflammation J:138824
Traddtm1.1Mak/Traddtm1.1Mak
(either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N))
abnormal spleen follicular dendritic cell network J:138824
absent spleen germinal center J:138824
decreased acute inflammation J:138824
decreased circulating interleukin-6 level J:138824
decreased inflammatory response J:138824
decreased interleukin-6 secretion J:138824
Traddtm1.1Mpa/Traddtm1.1Mpa
(involves: C57BL/6)
decreased interferon-beta secretion J:136289
Traddtm1.1Mpa/Traddtm1.1Mpa
(involves: BALB/cJ * C57BL/6)
abnormal interleukin level J:139030
abnormal spleen germinal center morphology J:139030
decreased circulating tumor necrosis factor level J:139030
decreased IgG level J:139030
increased susceptibility to bacterial infection J:139030
Traf1tm1Tsi/Traf1tm1Tsi
(involves: 129S4/SvJae * C57BL/6)
abnormal lymph node cell ratio J:72327
immune system phenotype J:72327
increased lymphocyte cell number J:72327
increased T cell proliferation J:72327
Traf2tm1a(EUCOMM)Wtsi/Traf2+
(C57BL/6N-Traf2tm1a(EUCOMM)Wtsi/Wtsi)
decreased alpha-beta T cell number J:211773
decreased CD8-positive, alpha-beta T cell number J:211773
Traf2tm1Mak/Traf2tm1Mak
(either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J))
absent lymph node germinal center J:44360
absent spleen germinal center J:44360
decreased double-positive T cell number J:44360
decreased immature B cell number J:44360
decreased lymphocyte cell number J:44360
decreased thymocyte number J:44360
increased circulating tumor necrosis factor level J:44360
increased granulocyte number J:44360
increased thymocyte apoptosis J:44360
lymphoid hypoplasia J:44360
spleen atrophy J:44360
thymus atrophy J:44360
Traf3m1Btlr/Traf3m1Btlr
(C57BL/6J-Traf3m1Btlr)
decreased mature B cell number J:212064
impaired humoral immune response J:212064
Traf3m2Btlr/Traf3m2Btlr
(C57BL/6J-Traf3m2Btlr)
decreased IgG level J:217797
decreased response to antigen J:217797
Traf3tm1Bal/Traf3tm1Bal
(involves: 129S4/SvJae * C57BL/6J)
abnormal B cell differentiation J:37065
abnormal T cell physiology J:37065
decreased double-positive T cell number J:37065
decreased leukocyte cell number J:37065
decreased thymocyte number J:37065
spleen hypoplasia J:37065
Traf3tm1Bshp/Traf3tm1Bshp
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL)
abnormal adaptive immunity J:124329
abnormal immune system organ morphology J:124329
abnormal immune system physiology J:124329
abnormal leukocyte morphology J:124329
abnormal lymph node B cell domain morphology J:124329
abnormal spleen germinal center morphology J:124329
autoimmune response J:124329
decreased B cell apoptosis J:124329
decreased T cell number J:124329
enlarged lymph nodes J:124329
enlarged spleen J:124329
increased anti-double stranded DNA antibody level J:124329
increased B cell number J:124329
increased follicular B cell number J:124329
increased IgA level J:124329
increased IgG2a level J:124329
increased IgG2b level J:124329
increased IgG3 level J:124329
increased IgG level J:124329
increased IgM level J:124329
increased marginal zone B cell number J:124329
increased spleen white pulp amount J:124329
increased transitional stage B cell number J:124329
Traf3ip2adjm/Traf3ip2adjm
(KOR-Traf3ip2adjm)
dermatitis J:162859
increased IgE level J:162859
Traf3ip2adjm/Traf3ip2adjm
(A.KOR-Traf3ip2adjm)
dermatitis J:162859
increased IgE level J:162859
Traf3ip2adjm/Traf3ip2adjm
(B6.KOR-Traf3ip2adjm)
dermatitis J:162859
increased IgE level J:162859
Traf3ip2adjm/Traf3ip2adjm
(C.KOR-Traf3ip2adjm)
dermatitis J:162859
increased IgE level J:162859
Traf3ip2adjm/Traf3ip2adjm
(AK.KOR-Traf3ip2adjm)
dermatitis J:162859
increased IgE level J:162859
Traf3ip2Gt(IST11484G7)Tigm/Traf3ip2Gt(IST11484G7)Tigm
(involves: C57BL/6N)
immune system phenotype J:177650
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix
(involves: 129/Sv * BALB/c)
abnormal immune system morphology J:93923
abnormal immune system physiology J:93923
abnormal spleen B cell corona morphology J:93923
enlarged lymph nodes J:93923
enlarged spleen J:93923
increased anti-double stranded DNA antibody level J:93923
increased anti-histone antibody level J:93923
increased anti-single stranded DNA antibody level J:93923
increased autoantibody level J:93923
increased B cell number J:93923
increased dendritic cell number J:93923
increased IgE level J:93923
increased IgG level J:93923
increased immunoglobulin level J:93923
increased inflammatory response J:93923
lymphoid hyperplasia J:93923
respiratory system inflammation J:93923
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix
(C.129-Traf3ip2tm1.1Lix)
blepharitis J:138560
enlarged submandibular lymph nodes J:138560
glomerulonephritis J:138560
increased autoantibody level J:138560
increased follicular B cell number J:138560
increased inflammatory response J:138560
increased marginal zone B cell number J:138560
increased transitional stage B cell number J:138560
kidney inflammation J:138560
lacrimal gland inflammation J:138560
parotid gland inflammation J:138560
stomatitis J:138560
submandibular gland inflammation J:138560
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix
(B6.129-Traf3ip2tm1.1Lix)
abnormal transitional stage B cell morphology J:187766
enlarged cervical lymph nodes J:187766
enlarged spleen J:187766
immune system phenotype J:187766
increased anti-chromatin antibody level J:187766
increased anti-double stranded DNA antibody level J:187766
increased anti-histone antibody level J:187766
increased anti-nuclear antigen antibody level J:187766
increased autoantibody level J:187766
increased B cell number J:187766
increased IgG1 level J:187766
increased IgG2c level J:187766
increased IgG level J:187766
increased immature B cell number J:187766
increased marginal zone B cell number J:187766
increased spleen weight J:187766
lymph node hyperplasia J:187766
spleen hyperplasia J:187766
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix
Tnfsf13btm1Msc/Tnfsf13btm1Msc

(involves: 129 * 129S2/SvPas * BALB/c)
decreased B cell number J:138560
decreased follicular B cell number J:138560
decreased mature B cell number J:138560
decreased transitional stage B cell number J:138560
enlarged lymph nodes J:93923
enlarged spleen J:93923
increased autoantibody level J:138560
Traf3ip2tm1Lix/Traf3ip2tm1.1Lix
Tg(CD19-cre/ERT2)1Cgn/0

(involves: 129/Sv * BALB/c)
enlarged lymph nodes J:93923
enlarged spleen J:93923
increased B cell number J:93923
increased dendritic cell number J:93923
increased immunoglobulin level J:93923
Traf3ip2tm1Sbn/Traf3ip2tm1Sbn
(either: B6.129-Traf3ip2tm1Sbn or (involves: 129) or (involves: 129 * BALB/c))
abnormal cytokine secretion J:144320
decreased interleukin-6 secretion J:144320
decreased susceptibility to autoimmune disorder J:144320
impaired eosinophil recruitment J:144320
impaired macrophage chemotaxis J:144320
impaired neutrophil recruitment J:144320
Traf3ip2tm1Sbn/Traf3ip2tm1Sbn
(involves: 129 * C57BL/6)
decreased inflammatory response J:191090
Traf3ip3tm1a(KOMP)Wtsi/Traf3ip3tm1a(KOMP)Wtsi
(C57BL/6N-Traf3ip3tm1a(KOMP)Wtsi/Wtsi)
decreased leukocyte cell number J:175295
Traf3ip3tm1b(KOMP)Wtsi/Traf3ip3tm1b(KOMP)Wtsi
(involves: BALB/cJ * C57BL/6N)
abnormal T cell differentiation J:226431
decreased CD4-positive, alpha-beta memory T cell number J:226431
decreased CD8-positive, alpha-beta memory T cell number J:226431
decreased regulatory T cell number J:226431
decreased T cell number J:226431
decreased thymocyte number J:226431
immune system phenotype J:226431
increased double-positive T cell number J:226431
increased gamma-delta T cell number J:226431
Traf4tm1Lind/Traf4tm1Lind
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:74252
lung inflammation J:74252
Traf4tm1Mrio/Traf4tm1Mrio
(involves: 129X1/SvJ)
abnormal dendritic cell physiology J:142780
immune system phenotype J:142780
Traf4tm2Lind/Traf4tm2Lind
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:74252
lung inflammation J:74252
Traf5tm1Hna/Traf5tm1Hna
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
abnormal B cell proliferation J:57114
abnormal humoral immune response J:57114
abnormal T cell proliferation J:57114
decreased IgG1 level J:57114
decreased IgM level J:57114
Traf6tm1.1Mpa/Traf6tm1.1Mpa
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
decreased circulating interleukin-6 level J:145306
Traf6tm1Jino/Traf6tm1Jino
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:77453
decreased immature B cell number J:77453
decreased lymph node number J:77453
Traf6tm1Mak/Traf6tm1Mak
(involves: 129P3/J)
abnormal macrophage physiology J:54467
abnormal osteoclast morphology J:54467
abnormal osteoclast physiology J:54467
decreased B cell proliferation J:54467
decreased tumor necrosis factor secretion J:54467
enlarged spleen J:54467
Traf6tm1Ywc/Traf6tm1Ywc
(Not Specified)
abnormal dendritic cell differentiation J:85808
abnormal dendritic cell physiology J:85808
abnormal lymph node morphology J:85808
abnormal spleen morphology J:85808
absent spleen white pulp J:85808
decreased dendritic cell number J:85808
decreased interleukin-6 secretion J:85808
decreased interleukin-12 secretion J:85808
enlarged spleen J:85808
thymus atrophy J:85808
Traf6tm2a(EUCOMM)Wtsi/Traf6tm2a(EUCOMM)Wtsi
(C57BL/6N-Traf6tm2a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
Traf6tm2Ywc/Traf6tm2Ywc
Tg(Cd4-cre)1Cwi/?

(involves: C57BL/6 * DBA/2)
abnormal lymphocyte anergy J:130882
increased activated T cell number J:130882
increased memory T cell number J:130882
Traf7em1(IMPC)Tcp/Traf7+
(C57BL/6NCrl-Traf7em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Trafd1tm1Ayos/Trafd1tm1Ayos
(involves: 129 * C57BL/6J)
decreased susceptibility to Riboviria infection J:144594
increased circulating interleukin-6 level J:144594
increased interleukin-6 secretion J:144594
increased interleukin-12 secretion J:144594
increased susceptibility to endotoxin shock J:144594
increased tumor necrosis factor secretion J:144594
Traj18em1Hwata/Traj18em1Hwata
(C57BL/6-Traj18em1Hwata)
abnormal cytokine secretion J:256533
absent NK T cells J:256533
Traj18em1Hwata/Traj18em1Hwata
(C.B6-Traj18em1Hwata)
abnormal cytokine secretion J:256533
absent NK T cells J:256533
Traj18tm1.1Kro/Traj18tm1.1Kro
(involves: C57BL/6NTac)
abnormal circulating interleukin-4 level J:232957
abnormal interferon-gamma secretion J:232957
absent NK T cells J:232957
decreased inflammatory response J:232957
Traj33em#Dig/Traj33em#Dig
(involves: C57BL/6)
decreased T cell number J:276912
immune system phenotype J:276912
Trak2em1(IMPC)Mbp/Trak2em1(IMPC)Mbp
(C57BL/6N-Trak2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Trap1em1(IMPC)Mbp/Trap1em1(IMPC)Mbp
(C57BL/6N-Trap1em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
decreased monocyte cell number J:211773
Trap1Gt(E150H04)Wrst/Trap1Gt(E150H04)Wrst
(involves: 129P2/OlaHsd * C57BL/6)
decreased inflammatory response J:226880
spleen hyperplasia J:226880
Trappc1em1(IMPC)Mbp/Trappc1+
(C57BL/6NCrl-Trappc1em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Trappc2lem1(IMPC)Mbp/Trappc2lem1(IMPC)Mbp
(C57BL/6N-Trappc2lem1(IMPC)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Trappc9tm1a(EUCOMM)Wtsi/Trappc9tm1a(EUCOMM)Wtsi
(C57BL/6N-Trappc9tm1a(EUCOMM)Wtsi/Wtsi)
blood in lymph vessels J:239583
decreased CD11b-low dendritic cell number J:211773
decreased gamma-delta T cell number J:211773
decreased KLRG1-positive NK cell number J:211773
increased CD11b-high dendritic cell number J:211773
increased Ly6C high monocyte number J:211773
increased Ly6C low monocyte number J:211773
increased monocyte cell number J:211773
Trappc10b2b2416Clo/Trappc10b2b2416Clo
(Trappc10b2b2416Clo)
thymus hypoplasia J:175213
Trat1tm1Lsmn/Trat1tm1Lsmn
(B6.129X1-Trat1tm1Lsmn)
lymph node hypoplasia J:108406
spleen hypoplasia J:108406
thymus hypoplasia J:108406
Trbv13-2tm1(CD2)Zhu/Trbv13-2tm1(CD2)Zhu
(involves: 129 * C57BL/6)
abnormal T cell differentiation J:121608
immune system phenotype J:121608
Trbv13-2tm1(CD2)Zhu/Trbv13-2tm1(CD2)Zhu
(involves: 129 * C57BL/6 * SJL)
abnormal T cell differentiation J:121608
Trbv14tm1Che/Trbv14tm1Che
(involves: 129S4/SvJae)
decreased T cell number J:92288
Trbv14tm2Che/Trbv14tm2Che
(involves: 129S4/SvJae)
decreased T cell number J:92288
Trbv15tm1Krg/Trbv15tm1Krg
(involves: 129S/SvEv * C57BL/6)
immune system phenotype J:95669
Trdmt1Gt(OST19279)Lex/Trdmt1Gt(OST19279)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased NK cell number J:103485
Trehem1(IMPC)H/Trehem1(IMPC)H
(C57BL/6N-Trehem1(IMPC)H/H)
increased eosinophil cell number J:211773
Trem1tm1(KOMP)Vlcg/Trem1tm1(KOMP)Vlcg
(C57BL/6N-Trem1tm1(KOMP)Vlcg/Wtsi)
increased anti-nuclear antigen antibody level J:211773
Trem1tm1.1Ahoru/Trem1tm1.1Ahoru
(C57BL/6-Trem1tm1.1Ahoru)
decreased monocyte cell number J:191035
decreased neutrophil cell number J:191035
Trem2em2Bwef/Trem2+
(involves: C57BL/6J * DBA/2J * FVB/N)
decreased macrophage cell number J:242126
Trem2em2Bwef/Trem2em2Bwef
(involves: C57BL/6J * DBA/2J * FVB/N)
decreased macrophage cell number J:242126
decreased macrophage proliferation J:242126
decreased microglial cell activation J:242126
impaired macrophage phagocytosis J:242126
increased circulating interleukin-6 level J:242126
increased circulating tumor necrosis factor level J:242126
increased macrophage apoptosis J:242126
increased susceptibility to endotoxin shock J:242126
Trem2tm1(KOMP)Vlcg/Trem2tm1(KOMP)Vlcg
(C57BL/6N-Trem2tm1(KOMP)Vlcg)
abnormal microglial cell physiology J:239381
decreased microglial cell activation J:239381
Trem2tm1Cln/Trem2tm1Cln
(B6.129P2-Trem2tm1Cln)
abnormal interferon level J:138057
abnormal interleukin level J:138057
abnormal tumor necrosis factor level J:138057
Treml1tm1Mcvic/Treml1tm1Mcvic
(C57BL/6-Treml1tm1Mcvic)
increased susceptibility to endotoxin shock J:150578
increased tumor necrosis factor secretion J:150578
Treml4tm1Ji/Treml4tm1Ji
(B6(Cg)-Treml4tm1Ji)
immune system phenotype J:180744
Trex1em3Gpt/Trex1em3Gpt
(C57BL/6JGpt-Trex1em3Gpt)
enlarged spleen J:330879
increased circulating tumor necrosis factor level J:330879
increased spleen weight J:330879
increased susceptibility to autoimmune disorder J:330879
Trex1tm1.1Fwpe/Trex1+
(involves: 129S1/SvImJ * 129S4/SvJae * 129S6/SvEvTac)
increased CD4-positive, alpha-beta T cell number J:220965
Trex1tm1.1Fwpe/Trex1tm1.1Fwpe
(involves: 129S1/SvImJ * 129S4/SvJae * 129S6/SvEvTac)
abnormal immune system organ morphology J:220965
abnormal T cell activation J:220965
bronchiolitis J:220965
enlarged lymph nodes J:220965
enlarged spleen J:220965
glomerulonephritis J:220965
heart inflammation J:220965
increased anti-double stranded DNA antibody level J:220965
increased B cell number J:220965
increased CD4-positive, alpha-beta T cell number J:220965
increased IgG level J:220965
increased inflammatory response J:220965
increased plasma cell number J:220965
increased regulatory T cell number J:220965
increased spleen weight J:220965
increased splenocyte number J:220965
increased susceptibility to systemic lupus erythematosus J:220965
lacrimal gland inflammation J:220965
lymphoid hyperplasia J:220965
pancreas inflammation J:220965
salivary gland inflammation J:220965
tubulointerstitial nephritis J:220965
Trex1tm1Tld/Trex1tm1Tld
(involves: 129P2/OlaHsd)
abnormal interferon secretion J:234263
abnormal spleen marginal zone morphology J:92264
enlarged lymph nodes J:92264
enlarged spleen J:92264
heart inflammation J:202757
increased autoantibody level J:202757
increased spleen B cell follicle size J:92264
myocarditis J:92264
skin inflammation J:202757
thymus cortex hypoplasia J:92264
Trex1tm1Tld/Trex1tm1Tld
(involves: 129P2/OlaHsd * C57BL/6)
dermatitis J:181257
folliculitis J:181257
glomerulonephritis J:181257
immune system phenotype J:181257
increased anti-nuclear antigen antibody level J:181257
increased IgG level J:181257
increased inflammatory response J:181257
increased susceptibility to systemic lupus erythematosus J:181257
kidney inflammation J:181257
myocarditis J:181257
myositis J:181257
skin inflammation J:181257
stomach inflammation J:181257
Trex1tm1Tld/Trex1tm1Tld
(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N)
heart inflammation J:234263
increased autoantibody level J:234263
increased inflammatory response J:234263
kidney inflammation J:234263
myositis J:234263
stomach inflammation J:234263
Trex1tm1Tld/Trex1tm1Tld
(involves: 129P2/OlaHsd * C57BL/6J)
dermatitis J:243357
increased susceptibility to autoimmune disorder J:243357
Trgc1tm1.2Dhr/Trgc1tm1.2Dhr
(either: 129S4/SvJae or (involves: 129S4/SvJae * C57BL/6))
decreased gamma-delta T cell number J:91304
Tria4STS/A/?
(involves: BALB/c * STS/A)
abnormal leukocyte physiology J:56029
Tria5STS/A/?
(involves: BALB/cHeA * STS/A)
abnormal leukocyte physiology J:56029
Trib1tm1Aki/Trib1tm1Aki
(involves: 129P2/OlaHsd)
abnormal spleen red pulp morphology J:196449
decreased eosinophil cell number J:196449
decreased interleukin-12 secretion J:126085
decreased macrophage cell number J:196449
decreased spleen iron level J:196449
increased neutrophil cell number J:196449
Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2+
Tg(Thy1-APP*)2.2Ingm/0

(involves: C57BL/6 * DBA/1)
microgliosis J:176575
Trib2Tg(Thy1-Trh/APP*)2.1Ingm/Trib2Tg(Thy1-Trh/APP*)2.1Ingm
(involves: C57BL/6 * DBA/1)
microgliosis J:176575
Trib2tm1Lex/Trib2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased B cell number J:82809
increased CD8-positive, alpha-beta T cell number J:82809
Trib3tm1Tord/Trib3tm1Tord
(involves: C57BL/6)
abnormal mast cell physiology J:192615
decreased mast cell degranulation J:192615
Triltm1.1Kaf/Triltm1.1Kaf
(involves: C57BL/6)
abnormal chemokine secretion J:301765
abnormal cytokine secretion J:301765
decreased interferon-beta secretion J:301765
decreased interleukin-6 secretion J:301765
decreased tumor necrosis factor secretion J:301765
Trim6em1Raj/Trim6em1Raj
(C57BL/6J-Trim6em1Raj)
abnormal response to infection J:326927
Trim7em1Jiew/Trim7em1Jiew
(C57BL/6-Trim7em1Jiew)
decreased susceptibility to Herpesvirales infection J:292408
decreased susceptibility to viral infection J:292408
Trim8tm1Hbsh/Trim8tm1Hbsh
(involves: 129S6/SvEvTac)
abnormal chemokine secretion J:251270
abnormal circulating chemokine level J:251270
decreased interleukin-6 secretion J:251270
decreased tumor necrosis factor secretion J:251270
immune system phenotype J:251270
increased circulating interleukin-6 level J:251270
increased circulating tumor necrosis factor level J:251270
increased interferon-beta secretion J:251270
increased interleukin-6 secretion J:251270
increased macrophage cytokine production J:251270
increased susceptibility to bacterial infection J:251270
increased susceptibility to bacterial infection induced morbidity/mortality J:251270
increased susceptibility to endotoxin shock J:251270
increased tumor necrosis factor secretion J:251270
Trim9em1(IMPC)Ccpcz/Trim9em1(IMPC)Ccpcz
(C57BL/6N-Trim9em1(IMPC)Ccpcz/Ccpcz)
decreased effector memory T-helper cell number J:211773
decreased spleen weight J:211773
Trim13em1(IMPC)Tcp/Trim13em1(IMPC)Tcp
(C57BL/6N-Trim13em1(IMPC)Tcp/Tcp)
enlarged thymus J:211773
Trim13tm1.1Jskg/Trim13tm1.1Jskg
(B6.129S7(Cg)-Trim13tm1.1Jskg)
abnormal circulating interferon level J:243916
decreased circulating interferon-beta level J:243916
decreased susceptibility to Picornaviridae infection induced morbidity/mortality J:243916
increased interferon-beta secretion J:243916
Trim14em1Rfw/Trim14em1Rfw
(involves: C57BL/6J)
decreased interferon-beta secretion J:249057
increased susceptibility to Herpesvirales infection J:249057
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:249057
Trim21tm1Mwah/Trim21+
(C57BL/6-Trim21tm1Mwah)
dermatitis J:151775
Trim21tm1Mwah/Trim21tm1Mwah
(C57BL/6-Trim21tm1Mwah)
abnormal interleukin level J:151775
abnormal T cell activation J:151775
abnormal tumor necrosis factor level J:151775
autoimmune response J:151775
dermatitis J:151775
enlarged lymph nodes J:151775
enlarged spleen J:151775
increased autoantibody level J:151775
increased inflammatory response J:151775
Trim25tm1Mura/Trim25+
Usp15L749R/Usp15+

(involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:259382
decreased susceptibility to parasitic infection induced morbidity/mortality J:259382
Trim25tm1Mura/Trim25tm1Mura
(involves: 129S4/SvJae)
decreased susceptibility to parasitic infection J:259382
decreased susceptibility to parasitic infection induced morbidity/mortality J:259382
Trim27Gt(345D11)Cmhd/Trim27Gt(345D11)Cmhd
(B6.129-Trim27Gt(345D11)Cmhd)
abnormal T-helper 1 physiology J:180433
abnormal T-helper 2 physiology J:180433
immune system phenotype J:180433
increased interferon-gamma secretion J:180433
increased tumor necrosis factor secretion J:180433
Trim30atm1Yjk/Trim30atm1Yjk
(B6.129P2-Trim30atm1Yjk)
abnormal CD4-positive, alpha-beta T cell physiology J:215171
abnormal T cell subpopulation ratio J:215171
increased CD4-positive, alpha-beta T cell number J:215171
increased T cell proliferation J:215171
Trim31em1Cya/Trim31em1Cya
(involves: C57BL/6)
abnormal circulating cytokine level J:243237
decreased susceptibility to induced colitis J:243237
increased circulating interleukin-1 beta level J:243237
increased Ly6C high monocyte number J:243237
increased neutrophil cell number J:243237
Trim33em1(IMPC)Tcp/Trim33+
(C57BL/6N-Trim33em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Trim33tm1Los/Trim33tm1Los
Tg(Cd4-cre)1Cwi/0

(involves: 129S2/SvPas * C57BL/6 * DBA/2)
immune system phenotype J:149449
Trim35em1Smoc/Trim35em1Smoc
(C57BL/6J-Trim35em1Smoc)
decreased circulating interferon-beta level J:303214
decreased macrophage cytokine production J:303214
increased susceptibility to Orthomyxoviridae infection J:303214
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality J:303214
Trim37Gt(RRO307)Byg/Trim37Gt(RRO307)Byg
(B6J.129P2-Trim37Gt(RRO307)Byg)
enlarged spleen J:232482
Trim38tm1(KOMP)Vlcg/Trim38tm1(KOMP)Vlcg
(involves: C57BL/6N)
increased circulating interferon-alpha level J:239773
increased circulating interferon-beta level J:239773
increased circulating interleukin-6 level J:239773
increased circulating tumor necrosis factor level J:239773
increased susceptibility to bacterial infection J:239773
increased susceptibility to bacterial infection induced morbidity/mortality J:239773
increased susceptibility to infection induced morbidity/mortality J:239773
Trim39tm1b(EUCOMM)Hmgu/Trim39tm1b(EUCOMM)Hmgu
(C57BL/6N-Trim39tm1b(EUCOMM)Hmgu/H)
increased large unstained cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Trim40em1Caox/Trim40em1Caox
(involves: C57BL/6J)
abnormal immune system physiology J:255265
abnormal macrophage physiology J:255265
decreased susceptibility to Riboviria infection induced morbidity/mortality J:255265
Trim45tm1a(KOMP)Wtsi/Trim45tm1a(KOMP)Wtsi
(B6Brd;B6Dnk;B6N-Trim45tm1a(KOMP)Wtsi Tyrc-Brd/Wtsi)
blood in lymph vessels J:239583
Trim46em1(IMPC)J/Trim46em1(IMPC)J
(C57BL/6NJ-Trim46em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Trim50tm1b(KOMP)Wtsi/Trim50tm1b(KOMP)Wtsi
(C57BL/6N-Trim50tm1b(KOMP)Wtsi/BayMmucd)
decreased spleen weight J:211773
Trim55tm1Slbt/Trim55tm1Slbt
(involves: 129 * C57BL/6)
decreased susceptibility to Coronaviridae infection J:268979
Trim56tm1a(EUCOMM)Wtsi/Trim56tm1a(EUCOMM)Wtsi
(C57BL/6N-Trim56tm1a(EUCOMM)Wtsi/Wtsi)
decreased regulatory T cell number J:211773
Trim58em1(IMPC)Mbp/Trim58em1(IMPC)Mbp
(C57BL/6N-Trim58em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Trim58tm2313.1Arte/Trim58tm2313.1Arte
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6N)
increased susceptibility to induced colitis J:279270
Trim58tm2313.2Arte/Trim58tm2313.2Arte
(involves: BALB/cJ * C57BL/6N)
increased susceptibility to induced colitis J:279270
Trim65em1Cya/Trim65em1Cya
(involves: C57BL/6)
decreased circulating interferon-alpha level J:240099
decreased circulating interferon-beta level J:240099
decreased interferon-alpha secretion J:240099
decreased interferon-beta secretion J:240099
increased susceptibility to Picornaviridae infection J:240099
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:240099
Trim65em2Cya/Trim65em2Cya
(involves: C57BL/6)
decreased interferon-beta secretion J:240099
Trim65em3Cya/Trim65em3Cya
(involves: C57BL/6)
decreased interferon-beta secretion J:240099
Trioem1(IMPC)H/Trio+
(C57BL/6NTac-Trioem1(IMPC)H/H)
increased neutrophil cell number J:211773
Trip6tm1b(EUCOMM)Hmgu/Trip6+
(C57BL/6N-Trip6tm1b(EUCOMM)Hmgu/Bay)
enlarged spleen J:211773
Trip10tm1.1Geha/Trip10tm1.1Geha
(B6.129S1-Trip10tm1.1Geha)
abnormal spleen germinal center morphology J:164363
abnormal T cell physiology J:164363
decreased IgE level J:164363
decreased IgG level J:164363
decreased spleen germinal center number J:164363
decreased spleen germinal center size J:164363
decreased susceptibility to type IV hypersensitivity reaction J:164363
Trip13tm1.1(KOMP)Vlcg/Trip13tm1.1(KOMP)Vlcg
(C57BL/6N-Trip13tm1.1(KOMP)Vlcg/Ucd)
increased leukocyte cell number J:211773
Trmq1C57BL/6J/Trmq1DBA/2J
(involves: C57BL/6J * DBA/2J)
abnormal CD4-positive, alpha beta T cell morphology J:77603
Trmq1DBA/2J/Trmq1DBA/2J
(involves: C57BL/6J * DBA/2J)
abnormal CD4-positive, alpha beta T cell morphology J:77603
Trmq2C57BL/6J/Trmq2C57BL/6J
(involves: C57BL/6J * DBA/2J)
abnormal CD4-positive, alpha beta T cell morphology J:77603
Trmq2C57BL/6J/Trmq2DBA/2J
(involves: C57BL/6J * DBA/2J)
abnormal CD4-positive, alpha beta T cell morphology J:77603
Trmq3DBA/1J/Trmq3FVB/N
(involves: DBA/1J * FVB/N)
abnormal CD4-positive, alpha beta T cell morphology J:116665
Trmq3FVB/N/?
(involves: DBA/1J * FVB/N)
abnormal CD4-positive, alpha beta T cell morphology J:94347
abnormal T cell proliferation J:94347
Trmq3FVB/N/Trmq3FVB/N
(involves: DBA/1J * FVB/N)
abnormal CD4-positive, alpha beta T cell morphology J:116665
Trmq4RIIIS/J/Trmq4RIIIS/J
Trmq5RIIIS/J/Trmq5RIIIS/J

(involves: B10.RIII * RIIIS/J)
abnormal CD4-positive, alpha beta T cell morphology J:95848
Trmt2atm2b(EUCOMM)Wtsi/Trmt2atm2b(EUCOMM)Wtsi
(C57BL/6N-Trmt2atm2b(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Trp53tm1.1Awbr/Trp53tm1.1Awbr
(involves: C57BL/6)
decreased thymocyte apoptosis J:173271
increased pro-B cell number J:169434
Trp53tm1.1Manf/Trp53tm1.1Manf
(Not Specified)
abnormal abdominal lymph node morphology J:201153
abnormal spleen morphology J:201153
abnormal spleen white pulp morphology J:201153
abnormal thymus morphology J:201153
decreased neutrophil cell number J:201153
small spleen J:201153
small thymus J:201153
Trp53tm1.1Manf/Trp53tm1.1Manf
(involves: C57BL/6J)
abnormal abdominal lymph node morphology J:201153
abnormal spleen morphology J:201153
abnormal spleen white pulp morphology J:201153
abnormal thymus morphology J:201153
decreased neutrophil cell number J:201153
small spleen J:201153
small thymus J:201153
Trp53tm1.1Thst/Trp53+
(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
spleen hyperplasia J:198482
Trp53tm1.1Thst/Trp53tm1.1Thst
(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
decreased thymocyte apoptosis J:198482
immune system phenotype J:198482
spleen hyperplasia J:198482
Trp53tm1.1Tldo/Trp53tm1.1Tldo
(involves: 129S2/SvPas * BALB/c * C57BL/6)
increased thymocyte apoptosis J:199308
Trp53tm1.1Wgu/Trp53tm1.1Wgu
(involves: 129S6/SvEvTac * C57BL/6)
decreased thymocyte apoptosis J:186159
Trp53tm1.2Awbr/Trp53+
(involves: C57BL/6)
abnormal lymphocyte morphology J:173271
abnormal Peyer's patch morphology J:173271
increased inflammatory response J:173271
liver inflammation J:173271
Trp53tm1.2Awbr/Trp53tm1.2Awbr
(involves: C57BL/6)
abnormal lymphocyte morphology J:173271
abnormal Peyer's patch morphology J:173271
adipose tissue inflammation J:173271
decreased thymocyte apoptosis J:173271
enlarged spleen J:173271
increased circulating interferon-gamma level J:173271
increased circulating interleukin-3 level J:173271
increased circulating interleukin-5 level J:173271
increased circulating interleukin-6 level J:173271
increased circulating tumor necrosis factor level J:173271
increased inflammatory response J:173271
increased splenocyte proliferation J:173271
liver inflammation J:173271
lung inflammation J:173271
Trp53tm1b(EUCOMM)Hmgu/Trp53tm1b(EUCOMM)Hmgu
(C57BL/6N-Trp53tm1b(EUCOMM)Hmgu/H)
increased large unstained cell number J:211773
Trp53tm1Brd/Trp53tm1Brd
(involves: 129S7/SvEvBrd)
abnormal thymus physiology J:175018
decreased thymocyte apoptosis J:186159
Trp53tm1Brd/Trp53tm1Brd
Trp73tm2Mak/Trp73tm2Mak

(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J)
decreased thymocyte apoptosis J:157905
Trp53tm1Brd/Trp53tm8Xu
(involves: 129S7/SvEvBrd)
decreased leukocyte cell number J:170216
Trp53tm1Glo/Trp53tm1Glo
(involves: 129S7/SvEvBrd * C57BL/6J)
decreased thymocyte apoptosis J:172038
Trp53tm1Holl/Trp53tm7.1Xu
(involves: 129P2/OlaHsd)
decreased thymocyte apoptosis J:160414
Trp53tm1Ldo/Trp53+
(involves: 129S7/SvEvBrd * C57BL/6)
decreased spleen weight J:73757
spleen hypoplasia J:73757
Trp53tm1Sia/Trp53tm1Sia
(involves: C57BL/6NCrlj * CBA/JNCrlj)
increased leukocyte cell number J:233347
increased spleen weight J:233347
increased thymus weight J:233347
Trp53tm1Thst/Trp53+
(involves: 129S1/Sv * 129X1/SvJ)
spleen hyperplasia J:198482
Trp53tm1Thst/Trp53tm1.1Thst
(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ)
spleen hyperplasia J:198482
Trp53tm1Thst/Trp53tm1Thst
(involves: 129S1/Sv * 129X1/SvJ)
decreased thymocyte apoptosis J:198482
Trp53tm1Tyj/Trp53+
(involves: 129S2/SvPas)
decreased thymocyte apoptosis J:158953
Trp53tm1Tyj/Trp53+
(involves: 129S2/SvPas * C57BL/6 * CBA)
decreased thymocyte apoptosis J:80311
Trp53tm1Tyj/Trp53tm1Tyj
(involves: 129S2/SvPas)
decreased splenocyte apoptosis J:195018
decreased T cell apoptosis J:109354
decreased thymocyte apoptosis J:158953, J:195018, J:126920
Trp53tm1Tyj/Trp53tm1Tyj
(involves: 129S2/SvPas * C57BL/6 * CBA)
decreased thymocyte apoptosis J:80311
Trp53tm1Tyj/Trp53tm1Tyj
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S2/SvPas * C57BL/6N * C57BL/10 * CBA/Ca)
abnormal interleukin secretion J:305794
Trp53tm1Tyj/Trp53tm1Tyj
Riok2tm1c(KOMP)Wtsi/Riok2+
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: 129S2/SvPas * C57BL/6N * C57BL/10 * CBA/Ca)
immune system phenotype J:305794
Trp53tm1Tyj/Trp53tm1Tyj
Xrcc4tm1Fwa/Xrcc4tm1Fwa

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal lymphopoiesis J:61973
Trp53tm1Xu/Trp53tm1Xu
(involves: 129S4/SvJae)
abnormal thymocyte apoptosis J:86185
Trp53tm1Yjc/Trp53tm1Yjc
(B6.129S1-Trp53tm1Yjc)
abnormal spleen marginal zone morphology J:195018
abnormal spleen white pulp morphology J:195018
decreased splenocyte apoptosis J:195018
enlarged spleen J:195018
immune system phenotype J:195018
Trp53tm2.1Snj/Trp53tm2.1Snj
(involves: 129S4/SvJae * C57BL/6)
abnormal thymus physiology J:175018
Trp53tm2.1Wgu/Trp53tm2.1Wgu
(involves: 129S6/SvEvTac * C57BL/6)
decreased thymocyte apoptosis J:186159
Trp53tm2Wahl/Trp53tm2Wahl
(involves: 129S4/SvJae * C57BL/6)
decreased leukocyte cell number J:174375
decreased spleen red pulp amount J:174375
Trp53tm2Xu/Trp53tm2Xu
(involves: 129S6/SvEvTac)
decreased T cell apoptosis J:109354
decreased T cell proliferation J:109354
Trp53tm3.1Glo/Trp53+
(B6.129S7-Trp53tm3.1Glo)
hepatosplenomegaly J:317504
increased leukocyte cell number J:317504
Trp53tm3.1Holl/Trp53tm3.1Holl
(Not Specified)
increased thymocyte apoptosis J:191183
Trp53tm7.1Xu/Trp53+
(Not Specified)
abnormal thymus physiology J:160414
Trp53tm7.1Xu/Trp53tm7.1Xu
(Not Specified)
abnormal thymus physiology J:160414
decreased thymocyte apoptosis J:160414
Trp53bp1Gt(OST94324)Lex/Trp53bp1Gt(OST94324)Lex
(involves: 129S5/SvEvBrd)
abnormal T cell differentiation J:83164
decreased mature B cell number J:83164
decreased T cell number J:83164
small thymus J:83164
thymus hypoplasia J:83164
Trp53bp1m2Btlr/Trp53bp1m2Btlr
(C57BL/6J-Trp53bp1m2Btlr)
decreased B cell number J:254841
decreased CD8-positive, naive alpha-beta T cell number J:254841
decreased IgD level J:254841
decreased IgG level J:254841
impaired humoral immune response J:254841
increased central memory CD4-positive, alpha-beta T cell number J:254841
Trp53bp1m3Btlr/Trp53bp1m3Btlr
(C57BL/6J-Trp53bp1m3Btlr)
decreased IgD level J:254848
Trp53bp1m4Btlr/Trp53bp1m4Btlr
(C57BL/6J-Trp53bp1m4Btlr)
decreased IgD level J:254852
Trp53bp1m5Btlr/Trp53bp1m5Btlr
(C57BL/6J-Trp53bp1m5Btlr)
decreased IgD level J:272848
Trp53bp1tm1Jc/Trp53bp1tm1Jc
(involves: 129 * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:82512
increased double-negative T cell number J:82512
thymus hypoplasia J:82512
Trp53bp1tm1Jc/Trp53bp1tm1Jc
(involves: 129)
abnormal class switch recombination J:194603, J:231089, J:307190
Trp53bp2tm1Cdlo/Trp53bp2+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal T cell physiology J:146764
Trp53bp2tm1Xlu/Trp53bp2tm1Xlu
(C.129S6-Trp53bp2tm1Xlu)
small thymus J:240594
Trp53inp1tm1Acar/Trp53inp1tm1Acar
(involves: 129/Sv * C57BL/6)
increased susceptibility to induced colitis J:118867
large intestinal inflammation J:118867
Trp53inp2em1(IMPC)Mbp/Trp53inp2em1(IMPC)Mbp
(C57BL/6N-Trp53inp2em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Trp63tm2Brd/Trp63+
(involves: 129S7/SvEvBrd)
enlarged lymph nodes J:100483
increased susceptibility to infection J:100483
kidney inflammation J:100483
uterine cervix inflammation J:100483
Trp73em1(IMPC)H/Trp73+
(C57BL/6NTac-Trp73em1(IMPC)H/H)
decreased spleen weight J:211773
increased eosinophil cell number J:211773
Trp73tm1Fmc/Trp73tm1Fmc
(involves: 129S4/SvJae)
chronic inflammation J:60896
conjunctivitis J:60896
increased susceptibility to bacterial infection J:60896
increased susceptibility to otitis media J:60896
rhinitis J:60896
sinus inflammation J:60896
Trp73tm2Mak/Trp73tm2Mak
(either: B6.129P2-Trp73tm2Mak or (involves: 129P2/OlaHsd * C57BL/6J))
increased thymocyte apoptosis J:157905
Trpa1tm1Jul/Trpa1+
(involves: 129P2/OlaHsd * C57BL/6)
abnormal acute inflammation J:115886
Trpc1em1(IMPC)H/Trpc1em1(IMPC)H
(C57BL/6N-Trpc1em1(IMPC)H/H)
increased spleen weight J:211773
Trpc3tm1.2Akon/Trpc3tm1.2Akon
(involves: 129S/SvEv)
immune system phenotype J:190105
Trpm2tm1.1Alp/Trpm2tm1.1Alp
(B6.129P2-Trpm2tm1.1Alp)
decreased circulating interferon-gamma level J:174397
decreased circulating interleukin-12 level J:174397
decreased circulating interleukin-12b level J:174397
decreased interferon-gamma secretion J:174397
decreased interleukin-12 secretion J:174397
increased susceptibility to bacterial infection J:174397
increased susceptibility to bacterial infection induced morbidity/mortality J:174397
Trpm2tm1Lhj/Trpm2tm1Lhj
(Not Specified)
abnormal macrophage morphology J:202791
abnormal macrophage physiology J:202791
Trpm2tm1Yamo/Trpm2tm1Yamo
(involves: 129S4/SvJae * C57BL/6J)
abnormal interferon level J:137676
abnormal interleukin level J:137676
abnormal leukocyte physiology J:137676
abnormal macrophage physiology J:137676
decreased inflammatory response J:137676
impaired neutrophil recruitment J:137676
Trpm4tm1.1Knt/Trpm4tm1.1Knt
(Not Specified)
abnormal dendritic cell physiology J:140991
decreased dendritic cell number J:140991
Trpm4tm1.1Knt/Trpm4tm1.1Knt
Trpm5tm1Csz/Trpm5tm1Csz

(involves: 129S1/Sv * 129X1/SvJ)
abnormal dendritic cell physiology J:140991
decreased dendritic cell number J:140991
Trpm4tm1.1Mfre/Trpm4tm1.1Mfre
(involves: 129S1/Sv * 129X1/SvJ * BALB/cJ)
increased susceptibility to type I hypersensitivity reaction J:118679
Trpm7tm1Agry/Trpm7+
(involves: 129)
increased susceptibility to type IV hypersensitivity reaction J:205665
Trpm7tm1Clph/Trpm7tm1.1Clph
Tg(Lck-cre)548Jxm/0

(involves: 129S4/SvJae * C57BL/6 * CBA)
abnormal T cell differentiation J:140630
abnormal T cell physiology J:140630
abnormal thymus cell ratio J:140630
abnormal thymus corticomedullary boundary morphology J:140630
abnormal thymus medulla morphology J:140630
abnormal thymus morphology J:140630
decreased T cell number J:140630
decreased thymocyte number J:140630
Trps1m1Anu/Trps1m1Anu
(C57BL/6NCrlAnu-Trps1m1Anu)
immune system phenotype J:104190
Trpv1tm1Jul/Trpv1tm1Jul
(involves: 129X1/SvJ * C57BL/6)
decreased susceptibility to endotoxin shock J:104828
Trpv1tm1Jul/Trpv1tm1Jul
(B6.129X1-Trpv1tm1Jul)
abnormal chemokine secretion J:154624
increased interleukin-6 secretion J:154624
increased tumor necrosis factor secretion J:154624
kidney inflammation J:154624
Trpv2tm1Mijc/Trpv2tm1Mijc
(involves: 129S6/SvEvTac * C57BL/6)
impaired macrophage chemotaxis J:158505
impaired macrophage phagocytosis J:158505
increased susceptibility to bacterial infection J:158505
increased susceptibility to bacterial infection induced morbidity/mortality J:158505
Trpv3Nh/Trpv3+
(involves: DS)
dermatitis J:42153
increased susceptibility to bacterial infection J:42153
Trpv3tm1.2Clph/Trpv3tm1.2Clph
(involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA)
erythroderma J:164741
Trpv5Hcalc1/Trpv5+
(involves: C3H/HeH * C57BL/6J)
kidney inflammation J:196612
Trpv5Hcalc1/Trpv5Hcalc1
(involves: C3H/HeH * C57BL/6J)
kidney inflammation J:196612
Trpv5m1Btlr/Trpv5m1Btlr
(C57BL/6J-Trpv5m1Btlr)
increased susceptibility to induced colitis J:192586
intestinal inflammation J:192586
Trpv5tm1Bind/Trpv5tm1Bind
(involves: 129 * C57BL/6)
increased osteoclast cell number J:86949
Try10em1(IMPC)J/Try10em1(IMPC)J
(C57BL/6NJ-Try10em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Ts(16C-tel)1Cje/0
(involves: C57BL/6J * Rb(11.16)2H * Rb(16.17)32Lub)
abnormal spleen B cell follicle morphology J:174270
abnormal spleen B cell follicle shape J:241597
abnormal spleen red pulp morphology J:174270
increased spleen B cell follicle size J:241597
Ts(1716)65Dn/0
(involves: C3H/HeJ * C57BL/6J * DBA/2J)
abnormal spleen B cell follicle morphology J:174270
abnormal spleen B cell follicle shape J:174270
abnormal spleen red pulp morphology J:174270
increased spleen B cell follicle size J:174270
Tsc22d3tm1.2Efmd/Y
(Not Specified)
abnormal susceptibility to autoimmune disorder J:201728
abnormal T cell subpopulation ratio J:201728
immune system phenotype J:201728
increased interferon-gamma secretion J:201728
increased interleukin-17 secretion J:201728
increased susceptibility to type IV hypersensitivity reaction J:201728
Tsc22d3tm1.2Hum/Y
(involves: 129S1/SvImJ)
abnormal thymus cell ratio J:223992
decreased DN3 thymocyte number J:223992
decreased thymus weight J:223992
increased DN4 thymocyte number J:223992
Tshrhyt/Tshrhyt
(CBy.RF-Tshrhyt/J)
decreased B cell number J:111014
increased pro-B cell number J:111014
TsilTg(Myc)12ALvn/TsilTg(Myc)12ALvn
(involves: C57BL/6 * SJL/J)
increased double-positive T cell number J:33857
Tsiq1BALB/cOla/Tsiq1BALB/cOla
(involves: BALB/cOla * C57BL/6Ola)
increased interleukin-4 secretion J:99489
Tsiq1BALB/cOla/Tsiq1BALB/cOla
Tsiq2BALB/cOla/Tsiq2BALB/cOla
Tsiq3BALB/cOla/Tsiq3C57BL/6Ola

(involves: BALB/cOla * C57BL/6Ola)
increased interleukin-4 secretion J:99489
Tsiq2BALB/cOla/Tsiq2BALB/cOla
(involves: BALB/cOla * C57BL/6Ola)
increased interleukin-4 secretion J:99489
Tsiq3BALB/cOla/Tsiq3C57BL/6Ola
(involves: BALB/cOla * C57BL/6Ola)
increased interleukin-4 secretion J:99489
Tslptm1(KOMP)Vlcg/Tslptm1(KOMP)Vlcg
(involves: C57BL/6 * C57BL/6NTac)
abnormal immune system physiology J:187770
abnormal immunoglobulin level J:187770
abnormal T-helper 2 cell differentiation J:187770
decreased acute inflammation J:187770
decreased circulating interleukin-4 level J:187770
increased interferon-gamma secretion J:187770
respiratory system inflammation J:187770
Tslptm1.1Pcn/Tslptm1.1Pcn
Tg(KRT14-cre)1Ipc/0

(involves: 129 * C57BL/6 * SJL)
decreased eosinophil cell number J:146511
decreased IgE level J:146511
decreased lymphocyte cell number J:146511
Tslptm1Mak/Tslptm1Mak
(B6.Cg-Tslptm1Mak)
colitis J:175844
immune system phenotype J:175844
Tslptm1Sfz/Tslptm1Sfz
(C.129(Cg)-Tslptm1Sfz)
immune system phenotype J:199558
Tslptm1Sfz/Tslptm1Sfz
(involves: 129)
abnormal interleukin secretion J:197193
abnormal T-helper 2 physiology J:197193
increased interleukin-5 secretion J:197193
increased interleukin-13 secretion J:197193
TsnGt(OST63223)Lex/TsnGt(OST63223)Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
immune system phenotype J:85466
Tspan2tm1Hbw/Tspan2tm1Hbw
(C57BL/6-Tspan2tm1Hbw)
microgliosis J:201143
Tspan9em1Tshu/Tspan9em1Tshu
(C57BL/6-Tspan9em1Tshu)
abnormal macrophage morphology J:307067
abnormal neutrophil morphology J:307067
decreased neutrophil cell number J:307067
Tspan32em1(IMPC)Mbp/Tspan32em1(IMPC)Mbp
(C57BL/6N-Tspan32em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Tspan32Gt(pMS-1)1Jmt/Tspan32Gt(pMS-1)1Jmt
(involves: 129S1/Sv)
increased T cell proliferation J:78033
Tspan33tm1Stsa/Tspan33tm1Stsa
(involves: 129S1/Sv * 129X1/SvJ)
abnormal spleen morphology J:143158
abnormal splenic cell ratio J:143158
enlarged spleen J:143158
increased monocyte cell number J:143158
Tspotm1.1Guwu/Tspotm1.1Guwu
(involves: C57BL/6)
increased NK cell number J:219189
Tssk5tm1.1(KOMP)Vlcg/Tssk5tm1.1(KOMP)Vlcg
(C57BL/6N-Tssk5tm1.1(KOMP)Vlcg/J)
decreased leukocyte cell number J:211773
Tsttm1(KOMP)Vlcg/Tsttm1(KOMP)Vlcg
(C57BL/6N-Tsttm1(KOMP)Vlcg/Ucd)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Tstd1em1(IMPC)J/Tstd1em1(IMPC)J
(C57BL/6NJ-Tstd1em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ttc7fsn-Jic/Ttc7fsn-Jic
(C3.INT-Ttc7fsn-Jic)
decreased spleen white pulp amount J:115742
decreased thymus weight J:115742
increased spleen red pulp amount J:115742
increased spleen weight J:115742
liver inflammation J:115742
Ttc7fsn/Ttc7fsn
(CByJ.A-Ttc7fsn)
enlarged spleen J:29200, J:30519
small thymus J:29200
thymus cortex hypoplasia J:29200
Ttc7fsn/Ttc7fsn
(involves: A/J)
stomach inflammation J:2777
Ttc7fsn/Ttc7fsn
(involves: A/J * BALB/cByJ)
increased dendritic epidermal T cell number J:14506
increased Langerhans cell number J:14506
Ttc7hea/Ttc7hea
(CFO)
enlarged spleen J:7515
increased leukocyte cell number J:7515
Ttc9tm1Vcl/Ttc9+
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
thymus hyperplasia J:241703
Ttc9tm1Vcl/Ttc9tm1Vcl
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
increased spleen weight J:241703
increased thymus weight J:241703
thymus hyperplasia J:241703
Ttc28tm1b(EUCOMM)Hmgu/Ttc28tm1b(EUCOMM)Hmgu
(C57BL/6N-Ttc28tm1b(EUCOMM)Hmgu/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Ttc39aos1tm1Kaf/Ttc39aos1tm1Kaf
(C57BL/6-Ttc39aos1tm1Kaf)
increased susceptibility to endotoxin shock J:234649
Tti2tm1b(KOMP)Wtsi/Tti2+
(C57BL/6N-Tti2tm1b(KOMP)Wtsi/Ics)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Ttll1Gt(OST372941)Lex/Ttll1Gt(OST372941)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
increased susceptibility to otitis media J:186050
rhinitis J:186050
Ttll1tm1Seto/Ttll1tm1Seto
(involves: 129S/SvEv * C57BL/6)
rhinosinusitis J:161297
Ttnmdm/Ttnmdm
(Not Specified)
myositis J:14016
Ttntm1.1Isrd/Ttntm1.1Isrd
(involves: 129S2/SvPas * C57BL/6)
myositis J:165576
Tubtub/Tubtub
(C57BL/6J-Tubtub)
abnormal Langerhans cell physiology J:13772
Tubal3em1(IMPC)J/Tubal3em1(IMPC)J
(C57BL/6NJ-Tubal3em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Tulp4tm1a(KOMP)Wtsi/Tulp4+
(involves: C57BL/6N * C57BL/6NRj)
absent connection between subcutaneous lymph vessels and lymph sac J:344151
immune system phenotype J:344151
Tulp4tm1a(KOMP)Wtsi/Tulp4tm1a(KOMP)Wtsi
(involves: C57BL/6N * C57BL/6NRj)
abnormal thymus topology J:344151
Tusc2tm1Avi/Tusc2+
(involves: 129S1/Sv * C57BL/6J)
arteritis J:119985
glomerulonephritis J:119985
increased anti-nuclear antigen antibody level J:119985
increased susceptibility to autoimmune disorder J:119985
Tusc2tm1Avi/Tusc2tm1Avi
(involves: 129S1/Sv * C57BL/6J)
abnormal NK cell differentiation J:119985
arteritis J:119985
decreased interleukin-15 secretion J:119985
decreased NK cell number J:119985
glomerulonephritis J:119985
increased anti-nuclear antigen antibody level J:119985
increased leukocyte cell number J:119985
increased susceptibility to autoimmune disorder J:119985
Tusc2tm1Avi/Tusc2tm1Avi
(involves: 129S1/Sv)
arteritis J:309768
chronic inflammation J:309768
decreased T cell proliferation J:309768
decreased thymocyte number J:309768
increased macrophage cell number J:309768
increased monocyte cell number J:309768
increased susceptibility to autoimmune disorder J:309768
Tvp23bem3Eetr/Tvp23bem3Eetr
(C57BL/6J-Tvp23bem3Eetr)
increased susceptibility to induced colitis J:340685
Tvp23bm1Btlr/Tvp23bm1Btlr
(C57BL/6J-Tvp23bm1Btlr)
increased susceptibility to induced colitis J:340685
Twist2tm1(cre)Dor/Twist2tm1(cre)Dor
(involves: 129/Sv * 129X1/SvJ)
abnormal interleukin level J:81485
abnormal spleen morphology J:81485
abnormal spleen white pulp morphology J:81485
abnormal thymus cortex morphology J:81485
abnormal thymus medulla morphology J:81485
abnormal thymus morphology J:81485
abnormal tumor necrosis factor level J:81485
thymus atrophy J:81485
Twsg1tm1Nosa/Twsg1tm1Nosa
(involves: 129P2/OlaHsd * C57BL/6)
abnormal B cell differentiation J:82738
abnormal spleen development J:82738
abnormal thymus development J:82738
decreased double-positive T cell number J:82738
decreased immature B cell number J:82738
decreased lymphocyte cell number J:82738
decreased pre-B cell number J:82738
decreased pro-B cell number J:82738
decreased spleen white pulp amount J:82738
decreased splenocyte number J:82738
decreased thymocyte number J:82738
increased granulocyte number J:82738
increased monocyte cell number J:82738
increased single-positive T cell number J:82738
increased thymocyte apoptosis J:82738
thymus atrophy J:82738
Txktm1Pls/Txktm1Pls
(involves: 129S6/SvEvTac)
abnormal cytokine secretion J:54449
increased susceptibility to parasitic infection J:54449
Txlnatm1b(EUCOMM)Hmgu/Txlna+
(C57BL/6N-Txlnatm1b(EUCOMM)Hmgu/H)
increased large unstained cell number J:211773
Txlnatm1b(EUCOMM)Hmgu/Txlnatm1b(EUCOMM)Hmgu
(C57BL/6N-Txlnatm1b(EUCOMM)Hmgu/H)
increased large unstained cell number J:211773
increased lymphocyte cell number J:211773
Txndc2tm1Lex/Txndc2tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
decreased circulating interleukin-6 level J:103485
Txniptm1Yu/Txniptm1Yu
(involves: 129)
abnormal mesenteric lymph node morphology J:96677
abnormal NK cell morphology J:96677
abnormal NK cell physiology J:96677
decreased CD8-positive, alpha-beta T cell number J:96677
decreased NK cell number J:96677
decreased NK T cell number J:96677
increased lymphocyte cell number J:96677
increased regulatory T cell number J:96677
increased T cell proliferation J:96677
Txnl1em1(IMPC)Tcp/Txnl1em1(IMPC)Tcp
(C57BL/6NCrl-Txnl1em1(IMPC)Tcp/Tcp)
increased monocyte cell number J:211773
Tyk2E775K/Tyk2E775K
(B10.D1-H2q/SgJ)
abnormal T-helper 1 physiology J:69051
decreased IgG1 level J:69051
decreased IgG2a level J:69051
decreased IgG level J:69051
decreased interferon-gamma secretion J:69051, J:120304
decreased susceptibility to induced arthritis J:69051
increased circulating interleukin-12 level J:120304
increased susceptibility to parasitic infection J:120304
Tyk2tm1Biat/Tyk2tm1Biat
(involves: 129P2/OlaHsd * C57BL/6)
abnormal response to infection J:116703
decreased interferon-gamma secretion J:65408
decreased macrophage nitric oxide production J:65408
increased susceptibility to Herpesvirales infection J:116703
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:116703
increased susceptibility to Riboviria infection J:65408
increased susceptibility to viral infection induced morbidity/mortality J:65408
Tyk2tm1Biat/Tyk2tm1Biat
(B6NCrl.129P2-Tyk2tm1Biat)
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:187818
increased susceptibility to Riboviria infection induced morbidity/mortality J:187818
Tyk2tm1Shmd/Tyk2tm1Shmd
(involves: 129P2/OlaHsd)
abnormal splenocyte physiology J:65409
abnormal T cell differentiation J:65409
abnormal T cell physiology J:65409
decreased interferon-gamma secretion J:65409
Tyk2tm2b(EUCOMM)Hmgu/Tyk2tm2b(EUCOMM)Hmgu
(C57BL/6N-Tyk2tm2b(EUCOMM)Hmgu/Ieg)
decreased plasmacytoid dendritic cell number J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Tyk2tm3.1Biat/Tyk2tm3.1Biat
(B6NCrl.129P2(C)-Tyk2tm3.1Biat)
increased susceptibility to Picornaviridae infection induced morbidity/mortality J:187818
increased susceptibility to Riboviria infection induced morbidity/mortality J:187818
Tymptm1Akiy/Tymptm1Akiy
Upp1tm1Akiy/Upp1tm1Akiy

(involves: 129X1/SvJ)
brain inflammation J:78036
Tyro3em1(IMPC)Ccpcz/Tyro3em1(IMPC)Ccpcz
(C57BL/6NCrl-Tyro3em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal thymus morphology J:211773
enlarged thymus J:211773
increased eosinophil cell number J:211773
Tyrobptm1.1Viv/Tyrobptm1.1Viv
(involves: 129P2/OlaHsd * C57BL/6)
decreased uterine NK cell number J:100668
Tyrobptm1.1Viv/Tyrobptm1.1Viv
(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6)
decreased susceptibility to type IV hypersensitivity reaction J:64764
impaired natural killer cell mediated cytotoxicity J:64764
increased dendritic cell number J:64764
Tyrobptm1.1Viv/Tyrobptm1.1Viv
(B6.129P2-Tyrobptm1.1Viv)
abnormal microglial cell morphology J:95232
abnormal myelopoiesis J:95232
abnormal osteoclast physiology J:129304, J:95232
Tyrobptm1Lll/Tyrobptm1Lll
(involves: 129P2/OlaHsd * C57BL/6)
abnormal osteoclast differentiation J:89583
decreased interferon-gamma secretion J:64763
decreased susceptibility to experimental autoimmune encephalomyelitis J:64763
decreased T cell proliferation J:64763
immune system phenotype J:64763
impaired natural killer cell mediated cytotoxicity J:64763
increased dendritic cell number J:64763
increased natural killer cell mediated cytotoxicity J:64763
Tyrobptm1Lll/Tyrobptm1Lll
(B6.129P2-Tyrobptm1Lll)
abnormal NK T cell physiology J:147867
decreased interferon-gamma secretion J:147867
Tyrobptm1Lll/Tyrobptm1Lll
(involves: 129P2/OlaHsd)
decreased susceptibility to induced arthritis J:158811
Tyrobptm1Ttk/Tyrobptm1Ttk
(involves: 129P2/OlaHsd * C57BL/6)
abnormal dendritic cell physiology J:110786
abnormal osteoclast morphology J:81823
abnormal osteoclast physiology J:81823
Tyrobptm1Ttk/Tyrobptm1Ttk
(B6.129P2-Tyrobptm1Ttk)
increased anti-double stranded DNA antibody level J:177613
increased autoantibody level J:177613
increased B cell proliferation J:177613
increased germinal center B cell number J:177613
increased IgG2a level J:177613
increased IgG3 level J:177613
increased interleukin-6 secretion J:177613
increased spleen germinal center number J:177613
increased spleen germinal center size J:177613
Tyrobptm1Viv/Tyrobptm1Viv
(B6.129P2-Tyrobptm1Viv)
increased susceptibility to Herpesvirales infection J:124749
U2af2em1(IMPC)J/U2af2+
(C57BL/6NJ-U2af2em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
U90926em1Dnkv/U90926em1Dnkv
(C57BL6/J-U90926em1Dnkv)
increased circulating interleukin-6 level J:340649
increased susceptibility to bacterial infection induced morbidity/mortality J:340649
increased susceptibility to endotoxin shock J:340649
Uacatm1Kiy/Uacatm1Kiy
(B6.129P2-Uacatm1Kiy)
abnormal Kupffer cell morphology J:157049
decreased dendritic cell number J:157049
increased tumor necrosis factor secretion J:157049
liver inflammation J:157049
lung inflammation J:157049
Ubash3btm1Jni/Ubash3btm1Jni
Ubash3atm1Jni/Ubash3atm1Jni

(Not Specified)
abnormal cytokine secretion J:89761
increased mature B cell number J:89761
increased splenocyte number J:89761
increased susceptibility to experimental autoimmune encephalomyelitis J:89761
increased T cell proliferation J:89761
Ubdtm1b(EUCOMM)Wtsi/Ubdtm1b(EUCOMM)Wtsi
(C57BL/6N-Ubdtm1b(EUCOMM)Wtsi/Ccpcz)
abnormal thymus morphology J:211773
decreased memory-marker CD4-positive NK T cell number J:211773
increased CD4-positive, CD25-positive NK T cell number J:211773
small thymus J:211773
Ubdtm1Smwe/Ubdtm1Smwe
(B6.129S6-Ubdtm1Smwe)
abnormal lymphocyte physiology J:110321
increased susceptibility to bacterial infection J:110321
Ube2btm1b(EUCOMM)Wtsi/Ube2b+
(C57BL/6N-Ube2btm1b(EUCOMM)Wtsi/Ics)
decreased basophil cell number J:211773
decreased neutrophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Ube2iem1(IMPC)J/Ube2i+
(C57BL/6NJ-Ube2iem1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Ube2j1tm1.2Hpl/Ube2j1tm1.2Hpl
(involves: BALB/cJ * C57BL/6 * C57BL/6N * SJL)
immune system phenotype J:218292
Ube2j2em1(IMPC)Rbrc/Ube2j2em1(IMPC)Rbrc
(C57BL/6NJcl-Ube2j2em1(IMPC)Rbrc/Rbrc)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
Ube2nem1(IMPC)Ccpcz/Ube2n+
(C57BL/6N-Ube2nem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Ube2nGt(OST374154)Lex/Ube2n+
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal leukocyte physiology J:120846
abnormal macrophage physiology J:120846
decreased B cell proliferation J:120846
decreased susceptibility to endotoxin shock J:120846
decreased T cell proliferation J:120846
Ube2ntm1Aki/Ube2ntm1Aki
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal macrophage physiology J:112287
Ube2stm1.1Smoc/Ube2stm1.1Smoc
(involves: C57BL/6)
abnormal macrophage physiology J:306461
decreased susceptibility to Herpesvirales infection J:306461
decreased susceptibility to Picornaviridae infection J:306461
decreased susceptibility to Picornaviridae infection induced morbidity/mortality J:306461
decreased susceptibility to Riboviria infection J:306461
increased circulating interferon-alpha level J:306461
increased circulating interferon-beta level J:306461
increased circulating interleukin-6 level J:306461
increased circulating tumor necrosis factor level J:306461
increased interferon level J:306461
increased interferon-beta secretion J:306461
Ube2wtm1d(EUCOMM)Wtsi/Ube2wtm1d(EUCOMM)Wtsi
(involves: 129 * C57BL/6N)
increased neutrophil cell number J:230053
Ube3bGt(RRJ142)Byg/Ube3bGt(RRJ142)Byg
(involves: 129P2/OlaHsd * CBA/Ca)
eye inflammation J:203652
lymphangiectasis J:203652
Ube3ctm1b(EUCOMM)Hmgu/Ube3ctm1b(EUCOMM)Hmgu
(C57BL/6N-Ube3ctm1b(EUCOMM)Hmgu/Rbrc)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Ube3ctm1b(EUCOMM)Hmgu/Ube3ctm1b(EUCOMM)Hmgu
(C57BL/6NCrl-Ube3ctm1b(EUCOMM)Hmgu/Rbrc)
decreased CD4-negative NK T cell number J:211773
decreased CD5-positive Ly6C-positive T cell number J:211773
decreased Ly6C-positive immature NK cell number J:211773
decreased Ly6C-positive NK T cell number J:211773
immune system phenotype J:211773
increased effector memory CD8-positive, alpha-beta T cell number J:211773
Ube4aem1(IMPC)Tcp/Ube4aem1(IMPC)Tcp
(C57BL/6N-Ube4aem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Ubl4bem1(IMPC)Ccpcz/Ubl4bem1(IMPC)Ccpcz
(C57BL/6N-Ubl4bem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Ubox5tm1b(EUCOMM)Hmgu/Ubox5tm1b(EUCOMM)Hmgu
(C57BL/6N-Ubox5tm1b(EUCOMM)Hmgu/Tcp)
increased neutrophil cell number J:211773
Ubqln4em1(IMPC)Mbp/Ubqln4em1(IMPC)Mbp
(C57BL/6NCrl-Ubqln4em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Ubtfem1(IMPC)Mbp/Ubtf+
(C57BL/6NCrl-Ubtfem1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased leukocyte cell number J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Uchl3tm1Tilg/Uchl3tm1Tilg
(involves: 129S1/Sv * C57BL/6)
immune system phenotype J:61093
Ucp2tm1Rcq/Ucp2tm1Rcq
(involves: 129X1/SvJ * C57BL/6J)
abnormal macrophage physiology J:66262
decreased susceptibility to bacterial infection J:66262
decreased susceptibility to infection induced morbidity/mortality J:66262
decreased susceptibility to parasitic infection J:66262
Uevldtm1a(EUCOMM)Wtsi/Uevldtm1a(EUCOMM)Wtsi
(C57BL/6N-Uevldtm1a(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Ufl1tm1c(EUCOMM)Wtsi/Ufl1tm1c(EUCOMM)Wtsi
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+

(involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/6N)
decreased granulocyte number J:238253
decreased leukocyte cell number J:238253
decreased lymphocyte cell number J:238253
decreased monocyte cell number J:238253
Ugcgem1(IMPC)H/Ugcg+
(C57BL/6NTac-Ugcgem1(IMPC)H/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Uggt1tm1a(KOMP)Wtsi/Uggt1+
(involves: C57BL/6N)
abnormal susceptibility to Picornaviridae infection J:244058
decreased susceptibility to Picornaviridae infection J:244058
decreased susceptibility to Picornaviridae infection induced morbidity/mortality J:244058
Ugt8atm1Pop/Ugt8atm1Pop
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:78426
Uhrf1tm1a(EUCOMM)Wtsi/Uhrf1+
(Not Specified)
increased NK cell number J:165965
Uhrf2tm1b(EUCOMM)Wtsi/Uhrf2tm1b(EUCOMM)Wtsi
(C57BL/6N-Uhrf2tm1b(EUCOMM)Wtsi/Tcp)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Ulk1tm1.1Thsn/Ulk1tm1.1Thsn
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
increased spleen weight J:139213
Ulk1tm1.1Thsn/Ulk1tm1.1Thsn
(involves: 129S1/Sv * 129X1/SvJ)
immune system phenotype J:235399
Ulk3em2(IMPC)Tcp/Ulk3em2(IMPC)Tcp
(C57BL/6NCrl-Ulk3em2(IMPC)Tcp/Tcp)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased neutrophil cell number J:211773
enlarged lymph nodes J:211773
Ulk4tm1Lex/Ulk4tm1Lex
(involves: 129S5/SvEvBrd * C57BL/6J)
increased susceptibility to otitis media J:185566
maxillary sinus inflammation J:185566
nasal inflammation J:185566
Umodem1Duf/Umod+
(C57BL/6J-Umodem1Duf)
kidney inflammation J:252597
Umodtm1.1Rvt/Umod+
(either: B6J.129-Umodtm1.1Rvt or (involves: 129S1/Sv * 129X1/SvJ))
kidney inflammation J:242593
Umodtm1.1Rvt/Umodtm1.1Rvt
(either: B6J.129-Umodtm1.1Rvt or (involves: 129S1/Sv * 129X1/SvJ))
kidney inflammation J:242593
Umodtm1Xrw/Umodtm1Xrw
(involves: 129S6/SvEvTac)
increased susceptibility to bacterial infection J:95431
Unc13dJinx/Unc13dJinx
(C57BL/6J-Unc13dJinx/Mmucd)
abnormal cytokine secretion J:119974
abnormal macrophage physiology J:105543
abnormal NK cell physiology J:119974
absent lymph node germinal center J:119974
decreased cytotoxic T cell cytolysis J:119974
enlarged spleen J:119974
hemophagocytosis J:119974
increased CD8-positive, alpha-beta T cell number J:119974
increased monocyte cell number J:119974
increased neutrophil cell number J:119974
increased susceptibility to Herpesvirales infection J:105543, J:119974
increased susceptibility to Riboviria infection J:105543, J:119974
Unc80em1(IMPC)Tcp/Unc80+
(C57BL/6N-Unc80em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Unc93b13d/Unc93b13d
(C57BL/6J-Unc93b13d)
abnormal antigen presentation via MHC class I J:105484
abnormal antigen presentation via MHC class II J:105484
abnormal circulating interferon level J:105484
abnormal dendritic cell antigen presentation J:105484
abnormal macrophage physiology J:105484
abnormal tumor necrosis factor secretion J:105484
decreased interleukin-12b secretion J:105484
increased circulating tumor necrosis factor level J:105484
increased susceptibility to bacterial infection J:105484
increased susceptibility to Herpesvirales infection J:105484
Unc93b13d/Unc93b13d
(C57BL/6-Unc93b13d)
abnormal dendritic cell antigen presentation J:159599
abnormal dendritic cell morphology J:159599
decreased interleukin-6 secretion J:159599
decreased interleukin-12b secretion J:159599
Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg
(involves: C57BL/6NTac)
abnormal dendritic cell antigen presentation J:211069
abnormal dendritic cell morphology J:211069
abnormal dendritic cell physiology J:211069
abnormal tumor necrosis factor level J:211069
decreased circulating interleukin-6 level J:211069
decreased circulating interleukin-12b level J:211069
Unc93b1tm1.1Kmiy/Unc93b1tm1.1Kmiy
(involves: 129P2/OlaHsd * C57BL/6)
abnormal cytokine secretion J:174308
abnormal T-helper 1 cell differentiation J:174308
abnormal T-helper 17 cell differentiation J:174308
decreased B cell proliferation J:174308
decreased interferon-alpha secretion J:174308
decreased interleukin-12b secretion J:174308
decreased marginal zone B cell number J:174308
decreased tumor necrosis factor secretion J:174308
enlarged spleen J:174308
glomerulonephritis J:174308
increased anti-nuclear antigen antibody level J:174308
increased autoantibody level J:174308
increased B cell number J:174308
increased B cell proliferation J:174308
increased CD4-positive, alpha-beta memory T cell number J:174308
increased IgG2a level J:174308
increased IgG2b level J:174308
increased interferon-alpha secretion J:174308
increased interleukin-12b secretion J:174308
increased memory T cell number J:174308
increased spleen weight J:174308
increased T-helper 1 cell number J:174308
increased T-helper 17 cell number J:174308
increased tumor necrosis factor secretion J:174308
liver inflammation J:174308
Ungtm1Tld/Ungtm1Tld
(Not Specified)
abnormal class switch recombination J:79590
decreased IgG3 level J:79590
enlarged lymph nodes J:85353
enlarged spleen J:85353
enlarged thymus J:85353
increased IgM level J:79590
lymphoid hyperplasia J:85353
spleen hyperplasia J:85353
Ungtm1Tld/Ungtm1Tld
(involves: 129P2/OlaHsd)
abnormal class switch recombination J:306598
abnormal somatic hypermutation frequency J:155454
Uoxem1Cli/Uoxem1Cli
(C57BL/6J-Uoxem1Cli)
abnormal cytokine level J:271949
kidney inflammation J:271949
Uoxin/Uoxin
(involves: C57BL/6J * DBA/2J)
chronic inflammation J:70677
Uoxtm1Bay/Uoxtm1Bay
(involves: 129S7/SvEvBrd * C57BL/6J)
tubulointerstitial nephritis J:16490
Upf2tm1Btp/Upf2tm1Btp
Lyz2tm1(cre)Ifo/?

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
immune system phenotype J:134765
Upf2tm1Btp/Upf2tm1Btp
Tg(Mx1-cre)1Cgn/0

(involves: 129P2/OlaHsd * C57BL/6 * CBA)
abnormal B cell number J:134765
decreased granulocyte number J:134765
decreased T cell proliferation J:134765
Upf3bem1(IMPC)Tcp/Y
(C57BL/6NCrl-Upf3bem1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
small thymus J:211773
Upf3bem1(IMPC)Tcp/Upf3bem1(IMPC)Tcp
(C57BL/6NCrl-Upf3bem1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
small thymus J:211773
Uqcrbtm1b(EUCOMM)Wtsi/Uqcrb+
(C57BL/6N-Uqcrbtm1b(EUCOMM)Wtsi/Ieg)
increased leukocyte cell number J:211773
Urahplt2/Urahplt2
(C57BL/6-Urahplt2)
abnormal NK cell morphology J:267227
decreased CD8-positive, alpha-beta T cell number J:267227
increased T cell proliferation J:267227
Uri1tm1.1Ndj/Uri1tm1.1Ndj
Albtm1(cre/ERT2)Mtz/Alb+

(B6.Cg-Albtm1(cre/ERT2)Mtz Uri1tm1.1Ndj)
liver inflammation J:217463
Urostm1Cged/Urostm1Cged
(involves: 129S2/SvPas)
enlarged spleen J:105776
increased spleen red pulp amount J:105776
Urostm2Rjde/Urostm3Rjde
(involves: 129S6/SvEvTac * C57BL/6)
enlarged spleen J:132542
increased spleen iron level J:132542
Usp4tm1Xilu/Usp4tm1Xilu
(B6.129-Usp4tm1Xilu)
increased splenocyte apoptosis J:173192
increased thymocyte apoptosis J:173192
Usp5tm1a(EUCOMM)Hmgu/Usp5+
(C57BL/6N-Usp5tm1a(EUCOMM)Hmgu/Wtsi)
decreased leukocyte cell number J:211773
Usp12tm1a(EUCOMM)Hmgu/Usp12tm1a(EUCOMM)Hmgu
(Not Specified)
decreased CD8-positive, alpha-beta T cell number J:165965
decreased IgA level J:165965
Usp13em1Nmw/Usp13em1Nmw
(B6.Cg-Usp13em1Nmw)
increased interleukin-1 beta secretion J:285981
increased interleukin-6 secretion J:285981
increased susceptibility to bacterial infection J:285981
increased tumor necrosis factor secretion J:285981
lung inflammation J:285981
Usp15em1Peih/Usp15em1Peih
(involves: C57BL/6)
abnormal macrophage physiology J:306461
Usp15L749R/Usp15+
(involves: 129S1/SvImJ * C57BL/6J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:259382
decreased susceptibility to parasitic infection induced morbidity/mortality J:259382
Usp15L749R/Usp15L749R
(involves: 129S1/SvImJ * C57BL/6J)
abnormal T-helper 1 physiology J:259382
decreased susceptibility to bacterial infection J:259382
decreased susceptibility to bacterial infection induced morbidity/mortality J:259382
decreased susceptibility to experimental autoimmune encephalomyelitis J:259382
decreased susceptibility to parasitic infection J:259382
decreased susceptibility to parasitic infection induced morbidity/mortality J:259382
immune system phenotype J:259382
Usp15L749R/Usp15tm1Pgrs
(involves: 129S1/SvImJ * C57BL/6J)
decreased susceptibility to experimental autoimmune encephalomyelitis J:259382
decreased susceptibility to parasitic infection induced morbidity/mortality J:259382
Usp15tm1b(EUCOMM)Wtsi/Usp15tm1b(EUCOMM)Wtsi
(C57BL/6N-Usp15tm1b(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Usp15tm1Pgrs/Usp15tm1Pgrs
(Not Specified)
decreased susceptibility to experimental autoimmune encephalomyelitis J:259382
decreased susceptibility to parasitic infection induced morbidity/mortality J:259382
Usp16tm1b(EUCOMM)Hmgu/Usp16+
(C57BL/6N-Usp16tm1b(EUCOMM)Hmgu/Nju)
increased basophil cell number J:211773
increased eosinophil cell number J:211773
Usp17lctm1Khb/Usp17lc+
(either: 129-Usp17lctm1Khb or (involves: 129S/SvEv * C57BL/6J))
decreased regulatory T cell number J:191761
increased B cell number J:191761
increased CD4-positive, alpha-beta T cell number J:191761
increased CD8-positive, alpha-beta T cell number J:191761
increased thymus weight J:191761
Usp18ity9/Usp18ity9
(involves: 129S1/SvImJ * C57BL/6)
abnormal lymphocyte morphology J:163843
decreased circulating interferon-gamma level J:163843
decreased interferon-gamma secretion J:163843
decreased leukocyte cell number J:163843
increased circulating interleukin-6 level J:163843
increased interleukin-6 secretion J:163843
increased susceptibility to bacterial infection J:163843
increased susceptibility to bacterial infection induced morbidity/mortality J:163843
increased susceptibility to endotoxin shock J:163843
Usp18ity9/Usp18tm1Dez
(involves: 129 * C57BL/6 * FVB/N)
increased susceptibility to bacterial infection J:163843
increased susceptibility to bacterial infection induced morbidity/mortality J:163843
Usp18tm1Dez/Usp18tm1Dez
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal cytokine level J:214425
decreased circulating interferon-alpha level J:214425
decreased circulating interferon-beta level J:214425
decreased circulating interferon-gamma level J:214425
decreased susceptibility to Coronaviridae infection J:214425
Usp20em1Dalin/Usp20em1Dalin
(involves: C57BL/6)
abnormal circulating chemokine level J:274572
decreased circulating interferon-beta level J:274572
decreased circulating interleukin-6 level J:274572
decreased interferon-beta secretion J:274572
decreased tumor necrosis factor secretion J:274572
increased susceptibility to Herpesvirales infection J:274572
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:274572
Usp21tm1.1Jhy/Usp21tm1.1Jhy
(B6.129S7(Cg)-Usp21tm1.1Jhy)
abnormal interferon level J:208320
decreased susceptibility to Riboviria infection J:208320
decreased susceptibility to Riboviria infection induced morbidity/mortality J:208320
enlarged spleen J:208320
increased circulating interferon-alpha level J:208320
increased circulating interferon-beta level J:208320
increased macrophage cell number J:208320
increased neutrophil cell number J:208320
increased spleen weight J:208320
increased splenocyte number J:208320
Usp21tm1a(EUCOMM)Wtsi/Usp21tm1a(EUCOMM)Wtsi
(C57BL/6N-Usp21tm1a(EUCOMM)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Usp22tm1b(KOMP)Wtsi/Usp22+
(C57BL/6N-Usp22tm1b(KOMP)Wtsi/Wtsi)
increased monocyte cell number J:211773
Usp25Gt(RRS805)Byg/Usp25Gt(RRS805)Byg
(involves: 129P2/OlaHsd)
decreased interferon-gamma secretion J:188557
increased interleukin-6 secretion J:188557
increased neutrophil cell number J:188557
increased susceptibility to experimental autoimmune encephalomyelitis J:188557
lung inflammation J:188557
Usp28Gt(EUCE0037g10)Hmgu/Usp28Gt(EUCE0037g10)Hmgu
(involves: 129P2/OlaHsd * C57BL/6J)
decreased spleen weight J:215354
decreased splenocyte number J:215354
immune system phenotype J:215354
Usp32em1(IMPC)Mhzh/Usp32+
(C57BL/6N-Usp32em1(IMPC)Mhzh/Mhzh)
decreased neutrophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Usp38em1Cya/Usp38em1Cya
(C57BL/6-Usp38em1Cya)
lung inflammation J:321973
Usp42tm2a(EUCOMM)Wtsi/Usp42tm2a(EUCOMM)Wtsi
(involves: C57BL/6 * C57BL/6N)
increased CD4-positive, alpha-beta T cell number J:213427
increased T cell number J:213427
Usp45em1(IMPC)H/Usp45em1(IMPC)H
(C57BL/6NTac-Usp45em1(IMPC)H/H)
decreased neutrophil cell number J:211773
decreased spleen weight J:211773
Usp49em1Gpt/Usp49em1Gpt
(involves: C57BL/6NGpt)
decreased susceptibility to Herpesvirales infection J:285681
decreased susceptibility to Herpesvirales infection induced morbidity/mortality J:285681
immune system phenotype J:285681
increased circulating interferon-beta level J:285681
increased circulating interleukin-6 level J:285681
increased interferon-beta secretion J:285681
increased interleukin-6 secretion J:285681
Usp54tm1b(KOMP)Wtsi/Usp54tm1b(KOMP)Wtsi
(C57BL/6N-Usp54tm1b(KOMP)Wtsi/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Utp4em1(IMPC)J/Utp4+
(C57BL/6NJ-Utp4em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
UvragTn(pb-Act-RFP)1.100107015-HRAZhu/UvragTn(pb-Act-RFP)1.100107015-HRAZhu
(involves: FVB/NJ)
abnormal interleukin level J:219546
abnormal tumor necrosis factor level J:219546
heart inflammation J:219546
Uxs1tm1Lex/Uxs1+
(B6;129S5-Uxs1tm1Lex/Mmucd)
abnormal humoral immune response J:171883
increased IgG1 level J:171883
Vamp2tm1Sud/Vamp2tm1Sud
(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:131926
Vamp3tm1Jpes/Vamp3tm1Jpes
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
immune system phenotype J:131926
Vamp4em1(IMPC)Ccpcz/Vamp4em1(IMPC)Ccpcz
(C57BL/6NCrl-Vamp4em1(IMPC)Ccpcz/Ccpcz)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Vamp8Gt(OST20346)Lex/Vamp8Gt(OST20346)Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal mast cell physiology J:131926
Vamp8tm1Hong/Vamp8tm1Hong
(involves: 129P2/OlaHsd * C57BL/6)
abnormal dendritic cell physiology J:131528
abnormal type I hypersensitivity reaction J:133439
decreased mast cell degranulation J:133439
immune system phenotype J:133439
Varc/Varc+
(C3H/HeJ-Varc/J)
increased susceptibility to otitis media J:241135
Varc/Varc+
(C3OuJ.C3-Varc/Kjn)
increased susceptibility to otitis media J:241135
Vav1m1Anu/Vav1m1Anu
(C57BL/6JAnu-Vav1m1Anu)
increased T cell number J:104190
Vav1m1Btlr/Vav1m1Btlr
(C57BL/6J-Vav1m1Btlr)
abnormal humoral immune response J:265128
decreased B-1 B cell number J:265128
decreased CD4-positive, alpha-beta T cell number J:265128
decreased CD8-positive, alpha-beta T cell number J:265128
decreased CD8-positive, naive alpha-beta T cell number J:265128
decreased IgD level J:265128
decreased IgG level J:265128
decreased single-positive T cell number J:265128
decreased T cell number J:265128
increased central memory CD4-positive, alpha-beta T cell number J:265128
increased central memory CD8 positive, alpha-beta T cell number J:265128
increased effector memory CD4-positive, alpha-beta T cell number J:265128
increased IgM level J:265128
Vav1m2Btlr/Vav1m2Btlr
(C57BL/6J-Vav1m2Btlr)
decreased B-1 B cell number J:265130
Vav1M3Btlr/Vav1M3Btlr
(C57BL/6J-Vav1M3Btlr)
decreased IgG level J:272527
impaired humoral immune response J:272527
Vav1M4Btlr/Vav1M4Btlr
(C57BL/6J-Vav1M4Btlr)
abnormal CD4-positive T cell differentiation J:272528
abnormal CD8-positive, alpha-beta T cell differentiation J:272528
abnormal T cell differentiation J:272528
decreased B-1 B cell number J:272528
decreased CD4-positive, alpha-beta T cell number J:272528
decreased CD8-positive, naive alpha-beta T cell number J:272528
increased central memory CD4-positive, alpha-beta T cell number J:272528
increased central memory CD8 positive, alpha-beta T cell number J:272528
increased effector memory CD4-positive, alpha-beta T cell number J:272528
increased effector memory CD8-positive, alpha-beta T cell number J:272528
Vav1M5Btlr/Vav1M5Btlr
(C57BL/6J-Vav1M5Btlr)
decreased CD8-positive, alpha-beta T cell number J:272529
Vav1tm1Tyb/Vav1tm1Tyb
(involves: 129S2/SvPas * 129S8/SvEv)
abnormal T cell physiology J:113270
decreased CD4-positive, alpha-beta T cell number J:113270
decreased double-negative T cell number J:113270
decreased T cell proliferation J:113270
Vav1tm1Tyb/Vav1tm1Tyb
(involves: 129S4/SvJae * 129S8/SvEv * C57BL/10 * C57BR/cd)
abnormal CD4-positive, alpha beta T cell morphology J:113270
abnormal negative T cell selection J:113270
Vav1tm1Tyb/Vav1tm1Tyb
(involves: 129S2/SvPas)
abnormal double-negative T cell morphology J:79323
abnormal T cell physiology J:86654, J:79323
decreased double-positive T cell number J:79323
decreased interferon-gamma secretion J:86654
decreased interleukin-2 secretion J:86654
decreased mature B cell number J:86654
decreased single-positive T cell number J:79323
decreased T cell proliferation J:86654
decreased thymocyte number J:86654
thymus hypoplasia J:79323
Vav1tm1Tyb/Vav1tm1Tyb
(C.129S2-Vav1tm1Tyb)
abnormal negative T cell selection J:79323
Vav1tm1Tyb/Vav1tm1Tyb
(involves: 129S2/SvPas * C57BL/10 * C57BR/cd)
abnormal CD4-positive, alpha beta T cell morphology J:79323
abnormal T cell physiology J:128985
decreased interleukin-2 secretion J:128985
decreased T cell proliferation J:128985
decreased tumor necrosis factor secretion J:128985
Vav1tm1Tyb/Vav1tm1Tyb
(either: (involves: 129S4/SvJae * 129S8/SvEv) or (involves: 129S4/SvJae * 129S8/SvEv * C57BL/10 * C57BR/cd))
abnormal CD8-positive, alpha-beta T cell physiology J:190087
abnormal immune system physiology J:190087
abnormal interleukin-2 secretion J:190087
abnormal lymphocyte cell number J:190087
abnormal T cell number J:190087
decreased double-positive T cell number J:190087
increased DN2 thymocyte number J:190087
increased DN3 thymocyte number J:190087
increased double-negative T cell number J:190087
Vav1tm1Tyb/Vav1tm1Tyb
Vav2tm1Kdf/Vav2tm1Kdf

(involves: 129S1/Sv * 129S2/SvPas)
decreased B cell proliferation J:86654
decreased double-negative T cell number J:86654
decreased double-positive T cell number J:86654
decreased interferon-gamma secretion J:86654
decreased interleukin-2 secretion J:86654
decreased mature B cell number J:86654
decreased single-positive T cell number J:86654
decreased T cell number J:86654
decreased T cell proliferation J:86654
decreased thymocyte number J:86654
Vav1tm1Tyb/Vav1tm1Tyb
Vav2tm1Kdf/Vav2tm1Kdf
Vav3tm1Swat/Vav3tm1Swat

(involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6)
abnormal B cell physiology J:86654
abnormal humoral immune response J:86654
abnormal T cell physiology J:86654
arrested B cell differentiation J:86654
arrested T cell differentiation J:86654
decreased B cell proliferation J:86654
decreased double-positive T cell number J:86654
decreased follicular B cell number J:86654
decreased IgG1 level J:86654
decreased IgG2b level J:86654
decreased IgG3 level J:86654
decreased IgM level J:86654
decreased immunoglobulin level J:86654
decreased interferon-gamma secretion J:86654
decreased interleukin-2 secretion J:86654
decreased marginal zone B cell number J:86654
decreased mature B cell number J:86654
decreased single-positive T cell number J:86654
decreased T cell number J:86654
decreased T cell proliferation J:86654
decreased thymocyte number J:86654
decreased transitional stage T2 B cell number J:86654
increased immature B cell number J:86654
increased transitional stage T1 B cell number J:86654
Vav1tm1Tyb/Vav1tm1Tyb
Vav2tm1Kdf/Vav2tm1Kdf
Vav3tm1Swat/Vav3tm1Swat

(involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac)
abnormal macrophage physiology J:145345
abnormal neutrophil physiology J:145345
abnormal NK cell physiology J:187430
decreased interleukin-10 secretion J:145345
decreased tumor necrosis factor secretion J:145345
Vav1tm1Tyb/Vav1tm1Tyb
Vav2tm1Tnr/Vav2tm1Tnr

(involves: 129P2/OlaHsd * 129S2/SvPas)
abnormal B cell physiology J:69807
decreased B cell number J:69807
decreased B cell proliferation J:69807
decreased CD4-positive, alpha-beta T cell number J:69807
decreased CD8-positive, alpha-beta T cell number J:69807
decreased follicular B cell number J:69807
decreased immature B cell number J:69807
decreased mature B cell number J:69807
Vav1tm1Tyb/Vav1tm1Tyb
Vav3tm1Swat/Vav3tm1Swat

(involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6)
decreased B cell proliferation J:86654
decreased double-negative T cell number J:86654
decreased double-positive T cell number J:86654
decreased interferon-gamma secretion J:86654
decreased interleukin-2 secretion J:86654
decreased mature B cell number J:86654
decreased single-positive T cell number J:86654
decreased T cell number J:86654
decreased T cell proliferation J:86654
Vav1tm2Bbd/Vav1tm2Bbd
(involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal T cell activation J:47596
abnormal T cell differentiation J:47596
decreased B-1 B cell number J:47596
decreased CD4-positive, alpha-beta T cell number J:47596
decreased CD8-positive, alpha-beta T cell number J:47596
decreased interleukin-2 secretion J:47596
decreased T cell proliferation J:47596
immune system phenotype J:47596
thymus hypoplasia J:47596
Vav1tm2Bbd/Vav1tm2Bbd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal B cell number J:55647
abnormal lymph node cell ratio J:69806
abnormal response to infection J:55647
abnormal splenic cell ratio J:69806
abnormal T cell differentiation J:47596
abnormal T cell number J:47596
decreased B cell proliferation J:55647, J:69806
decreased B-1 B cell number J:55647
decreased CD4-positive, alpha-beta T cell number J:47596
decreased CD8-positive, alpha-beta T cell number J:47596
decreased IgG1 level J:55647
decreased IgG2a level J:55647
decreased IgG3 level J:69806
decreased IgG level J:55647
increased double-negative T cell number J:47596
increased transitional stage B cell number J:69806
Vav1tm2Bbd/Vav1tm2Bbd
(B6.129-Vav1tm2Bbd)
abnormal CD4-positive T cell differentiation J:141390
abnormal positive T cell selection J:141390
abnormal T cell physiology J:141390
decreased double-positive T cell number J:141390
decreased interleukin-4 secretion J:71161
decreased NK T cell number J:71161
decreased T cell number J:141390
immune system phenotype J:71161
impaired natural killer cell mediated cytotoxicity J:71161
Vav1tm2Bbd/Vav1tm2Bbd
Vav2tm1Kdf/Vav2tm1Kdf

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal B cell activation J:69806
abnormal B cell differentiation J:69806
abnormal lymph node cell ratio J:69806
abnormal splenic cell ratio J:69806
abnormal T cell differentiation J:69806
decreased B cell number J:69806
decreased B cell proliferation J:69806
decreased B-1 B cell number J:69806
decreased CD8-positive, alpha-beta T cell number J:69806
decreased IgG1 level J:69806
decreased IgG2b level J:69806
decreased IgG3 level J:69806
decreased IgM level J:69806
decreased immunoglobulin level J:69806
decreased mature B cell number J:69806
decreased T cell number J:69806
thymus hypoplasia J:69806
Vav1tm2Tyb/Vav1tm2Tyb
(involves: 129S4/SvJae * 129S8/SvEv)
abnormal T cell physiology J:113270
decreased CD4-positive, alpha-beta T cell number J:113270
decreased double-negative T cell number J:113270
decreased T cell proliferation J:113270
Vav1tm2Tyb/Vav1tm2Tyb
(involves: 129S4/SvJae * 129S8/SvEv * C57BL/10 * C57BR/cd)
abnormal CD4-positive, alpha beta T cell morphology J:113270
abnormal negative T cell selection J:113270
Vav1tm4Tyb/Vav1tm4Tyb
(either: 129S8.129S4-Vav1tm4Tyb or (involves: 129S4/SvJae * 129S8/SvEv * C57BL/10 * C57BR/cd))
abnormal CD4-positive, alpha-beta T cell physiology J:190087
abnormal CD8-positive, alpha-beta T cell physiology J:190087
abnormal immune serum protein physiology J:190087
abnormal immune system physiology J:190087
abnormal interleukin-2 secretion J:190087
abnormal lymphocyte cell number J:190087
abnormal T cell number J:190087
abnormal T cell physiology J:190087
increased circulating interferon-gamma level J:190087
increased DN2 thymocyte number J:190087
increased DN3 thymocyte number J:190087
Vav2tm1Kdf/Vav2tm1Kdf
(involves: 129S1/Sv * C57BL/6)
decreased B cell proliferation J:69806
decreased IgG3 level J:69806
decreased mature B cell number J:69806
Vav2tm1Kdf/Vav2tm1Kdf
Vav3tm1Swat/Vav3tm1Swat

(involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6)
immune system phenotype J:86654
Vav2tm1Tnr/Vav2tm1Tnr
(involves: 129P2/OlaHsd)
abnormal class switch recombination J:69807
decreased B cell number J:69807
decreased B cell proliferation J:69807
decreased IgG1 level J:69807
decreased IgG2b level J:69807
decreased IgG3 level J:69807
decreased IgM level J:69807
decreased spleen germinal center number J:69807
Vcam1tm1Dmil/Vcam1tm1Dmil
(either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6))
increased monocyte cell number J:69597
Vcam1tm1Dmil/Vcam1tm1Dmil
(C.129S4-Vcam1tm1Dmil)
increased B cell number J:69597
increased leukocyte cell number J:69597
increased monocyte cell number J:69597
increased T cell number J:69597
Vcam1tm2Flv/Vcam1tm3Flv
Tg(Tek-cre)12Flv/0

(involves: 129S1/Sv * C3H * C57BL/6)
abnormal B cell physiology J:68147
abnormal CD4-positive, alpha-beta T cell physiology J:68147
abnormal CD8-positive, alpha-beta T cell physiology J:68147
abnormal lymphocyte physiology J:68147
abnormal splenic cell ratio J:107447
decreased B cell number J:68147
decreased CD4-positive, alpha-beta T cell number J:68147
decreased CD8-positive, alpha-beta T cell number J:68147
decreased immature B cell number J:68147
increased immature B cell number J:68147
increased leukocyte cell number J:107447, J:68147
spleen hyperplasia J:107447
Vcam1tm2Roml/Vcam1tm2Roml
Tg(Mx1-cre)1Cgn/?

(involves: 129S1/Sv * C57BL/6 * CBA)
abnormal humoral immune response J:68148
decreased B cell number J:68148
decreased mature B cell number J:68148
decreased transitional stage B cell number J:68148
increased B cell number J:68148
increased immature B cell number J:68148
increased mature B cell number J:68148
increased transitional stage B cell number J:68148
Vcanem2(IMPC)Mbp/Vcan+
(C57BL/6NCrl-Vcanem2(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Vcptm1Itl/Vcp+
(B6.129S-Vcptm1Itl)
abnormal osteoclast differentiation J:166230
increased osteoclast cell number J:166230
Vdac2tm1.1Ehyc/Vdac2tm1.1Ehyc
Bak1tm1Thsn/Bak1tm1Thsn
Tg(Lck-cre)1Cwi/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2)
immune system phenotype J:220951
Vdac2tm1.1Ehyc/Vdac2tm1.1Ehyc
Baxtm2Sjk/Baxtm2Sjk
Tg(Lck-cre)1Cwi/?

(involves: 129X1/SvJ * C57BL/6 * DBA/2)
decreased thymocyte number J:220951
small thymus J:220951
Vdac2tm1.1Ehyc/Vdac2tm1.1Ehyc
Tg(Lck-cre)1Cwi/?

(involves: 129X1/SvJ * C57BL/6 * DBA/2)
abnormal thymocyte apoptosis J:220951
decreased thymocyte number J:220951
small thymus J:220951
Vdrtm1Gcm/Vdrtm1Gcm
Tg(Col2a1-cre)1Bhr/?

(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
decreased osteoclast cell number J:117377
Vdrtm1Mbd/Vdrtm1Mbd
(involves: 129S4/SvJae * C57BL/6)
abnormal interleukin level J:107077
abnormal tumor necrosis factor level J:107077
immune system phenotype J:107077
increased susceptibility to induced colitis J:130511
increased thymus weight J:107077
intestinal inflammation J:107077
thymus hyperplasia J:107077
Vdrtm1Rge/Vdrtm1Rge
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
abnormal macrophage physiology J:134827
decreased susceptibility to parasitic infection J:134827
Vdrtm1Ska/Vdrtm1Ska
(involves: C57BL/6NCrlj * CBA/JNCrlj)
abnormal macrophage chemotaxis J:112519
decreased splenocyte proliferation J:112519
decreased susceptibility to autoimmune diabetes J:112519
dermatitis J:111828
Vdrtm1Ska/Vdrtm1Ska
(NOD.Cg-Vdrtm1Ska/CmatJ)
abnormal chemokine secretion J:127787
abnormal dendritic cell differentiation J:127787
abnormal interleukin-1 secretion J:127787
abnormal T cell number J:127787
decreased interleukin-6 secretion J:127787
decreased regulatory T cell number J:127787
increased susceptibility to autoimmune diabetes J:127787
Vdrtm2Ska/Vdrtm2Ska
(involves: C57BL/6NCrlj * CBA/JNCrlj)
ear inflammation J:111828
Vegfatm1.1Nagy/Vegfatm1.1Nagy
(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymphatic vessel morphology J:64090
Vegfatm1Pec/Vegfatm1Pec
(involves: 129S1/Sv * 129X1/SvJ)
abnormal thymus morphology J:81698
athymia J:81698
decreased lymphocyte cell number J:81698
ectopic thymus J:81698
thymus hypoplasia J:81698
Vegfatm2Gne/Vegfatm2Gne
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129/Sv * 129P2/OlaHsd)
decreased inflammatory response J:107682
Vegfatm2Gne/Vegfatm2Gne
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129/Sv * 129P2/OlaHsd * C57BL/6)
immune system phenotype J:148597
Vegfatm2Gne/Vegfatm2Gne
Tg(SFTPC-cre)#Mliu/0

(involves: 129/Sv * ICR)
lung inflammation J:158566
Vegfctm1Ali/Vegfc+
(involves: 129S1/Sv * 129X1/SvJ * ICR)
abnormal lymph circulation J:87394
lymphatic vessel hypoplasia J:87394
Vegfctm1Ali/Vegfc+
(involves: 129S1/Sv * 129X1/SvJ)
lymphatic vessel hypoplasia J:137909
Vegfctm1Ali/Vegfc+
Tg(KRT14-FIGF)2Ali/0

(involves: 129S1/Sv * 129X1/SvJ * FVB/N)
lymphatic vessel hyperplasia J:137909
Vegfctm1Ali/Vegfctm1Ali
(involves: 129S1/Sv * 129X1/SvJ * ICR)
absent lymphatic vessels J:87394
Vegfctm1Ali/Vegfctm1Ali
(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymphangiogenesis J:137909
abnormal lymphatic vessel morphology J:137909
Vegfdem1(IMPC)Ccpcz/Vegfdem1(IMPC)Ccpcz
(C57BL/6NCrl-Vegfdem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Vegfdtm1Hrl/Y
(involves: 129S/SvEv * Swiss)
immune system phenotype J:153734
Vegfdtm1Mach/Vegfdtm1Mach
Vegfctm1Ali/Vegfctm1Ali

(involves: 129S1/Sv * 129X1/SvJ)
abnormal lymphangiogenesis J:137909
abnormal lymphatic vessel morphology J:137909
Vezf1tm1Stmn/Vezf1+
(B6.129-Vezf1tm1Stmn)
abnormal lymphatic vessel morphology J:99326
Vgfem1(IMPC)H/Vgfem1(IMPC)H
(C57BL/6NTac-Vgfem1(IMPC)H/H)
decreased spleen weight J:211773
Vhltm1Jae/Vhltm1Jae
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJae)
increased inflammatory response J:107682
Vhltm1Jae/Vhltm1Jae
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

(involves: 129S4/SvJae * CD-1)
decreased lymphocyte cell number J:186085
enlarged spleen J:186085
Vhltm1Mcs/Vhltm1Mcs
(involves: 129S4/SvJae * C57BL/6 * FVB/N)
abnormal spleen morphology J:130780
decreased spleen white pulp amount J:130780
increased leukocyte cell number J:130780
increased spleen red pulp amount J:130780
increased spleen weight J:130780
Vimtm1Cba/Vimtm1Cba
(involves: 129S2/SvPas * C57BL/6)
abnormal cellular extravasation J:129405
abnormal leukocyte adhesion J:129405
abnormal leukocyte migration J:129405
abnormal leukocyte tethering or rolling J:129405
immune system phenotype J:125280
Viptm1Clw/Viptm1Clw
(involves: 129S/Sv * C57BL/6)
lung inflammation J:132313
Vipr2tm1Ajh/Vipr2tm1Ajh
(B6.129P2-Vipr2tm1Ajh)
abnormal cytokine secretion J:72933
decreased IgE level J:72933
decreased interleukin-4 secretion J:72933
decreased susceptibility to type I hypersensitivity reaction J:72933
increased interferon-gamma secretion J:72933
increased interleukin-2 secretion J:72933
increased susceptibility to type IV hypersensitivity reaction J:72933
Vkorc1l1em1(IMPC)J/Vkorc1l1em1(IMPC)J
(C57BL/6NJ-Vkorc1l1em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Vldlrem1(IMPC)Mbp/Vldlrem1(IMPC)Mbp
(C57BL/6N-Vldlrem1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
Vms1A/J/Vms1A/J
(involves: A/J * C57BL/10SnSg)
myocarditis J:121574
Vnn1tm1Pna/Vnn1tm1Pna
(involves: 129P2/OlaHsd)
immune system phenotype J:65449
Vnn3em1(IMPC)Ccpcz/Vnn3em1(IMPC)Ccpcz
(C57BL/6NCrl-Vnn3em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Vpreb1atm1Ilm/Vpreb1a+
Vpreb1btm1Ilm/Vpreb1btm3Ilm

(involves: 129P2/OlaHsd * C57BL/6)
immune system phenotype J:104211
Vpreb1atm1Ilm/Vpreb1atm1Ilm
(involves: 129P2/OlaHsd * C57BL/6)
abnormal pre-B cell morphology J:53512
arrested B cell differentiation J:53512
immune system phenotype J:53512
Vpreb1atm1Ilm/Vpreb1atm1Ilm
(B6.129P2-Vpreb1atm1Ilm)
decreased pre-B cell number J:104211
increased pre-B cell number J:104211
Vpreb1atm1Ilm/Vpreb1atm1Ilm
Vpreb1btm1Ilm/Vpreb1b+

(involves: 129P2/OlaHsd * C57BL/6)
decreased mature B cell number J:104211
decreased pre-B cell number J:104211
increased pre-B cell number J:104211
Vpreb1atm1Ilm/Vpreb1atm1Ilm
Vpreb1btm1Ilm/Vpreb1btm1Ilm

(B6.129P2-Vpreb1atm1Ilm Vpreb1btm1Ilm)
abnormal B cell differentiation J:67609
abnormal immature B cell morphology J:67609
abnormal splenic cell ratio J:67609
decreased B-1a cell number J:67609
decreased IgG level J:67609
decreased mature B cell number J:67609
decreased pre-B cell number J:67609
immune system phenotype J:67609
increased pre-B cell number J:67609
Vpreb1btm3Ilm/Vpreb1btm3Ilm
(B6.129P2-Vpreb1btm3Ilm)
immune system phenotype J:104211
Vps4atm1b(EUCOMM)Hmgu/Vps4a+
(C57BL/6N-Vps4atm1b(EUCOMM)Hmgu/Bay)
enlarged spleen J:211773
increased spleen weight J:211773
Vps13atm1b(EUCOMM)Wtsi/Vps13atm1b(EUCOMM)Wtsi
(C57BL/6N-Vps13atm1b(EUCOMM)Wtsi/Wtsi)
decreased plasmacytoid dendritic cell number J:211773
decreased T-helper cell number J:211773
Vps13bem1(IMPC)Tcp/Vps13bem1(IMPC)Tcp
(C57BL/6N-Vps13bem1(IMPC)Tcp/Tcp)
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
small spleen J:211773
Vps13btm1.2Ics/Vps13btm1.2Ics
(involves: C57BL/6N)
eye inflammation J:296007
Vps33aem2(IMPC)Tcp/Vps33a+
(C57BL/6NCrl-Vps33aem2(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
increased spleen weight J:211773
Vps33btm1.1Arte/Vps33btm1.1Arte
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+

(involves: C57BL/6 * C57BL/6J)
decreased dendritic cell number J:222766
decreased lymphocyte cell number J:222766
enlarged spleen J:222766
increased macrophage cell number J:222766
increased monocyte cell number J:222766
increased neutrophil cell number J:222766
Vps35tm1.1Mjff/Vps35tm1.1Mjff
(B6.Cg-Vps35tm1.1Mjff)
microgliosis J:303283
Vps54wr/Vps54wr
(involves: C57BL/6J * C57BL/Fa)
increased microglial cell activation J:181019
Vrk3em1(IMPC)Mbp/Vrk3em1(IMPC)Mbp
(C57BL/6NCrl-Vrk3em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Vsig4tm1Gne/Vsig4tm1Gne
(involves: C57BL/6N)
increased susceptibility to bacterial infection J:138691
Vsig4tm1Gne/Vsig4tm1Gne
(C57BL/6-Vsig4tm1Gne)
abnormal macrophage physiology J:281762
decreased susceptibility to induced colitis J:281762
increased circulating interleukin-1 beta level J:281762
increased interleukin-1 beta secretion J:281762
increased susceptibility to experimental autoimmune encephalomyelitis J:281762
increased T-helper 1 cell number J:281762
increased T-helper 17 cell number J:281762
Vsig10em1(IMPC)Wtsi/Vsig10em1(IMPC)Wtsi
(C57BL/6N-Vsig10em1(IMPC)Wtsi/Wtsi)
increased leukocyte cell number J:211773
Vsirtm1Lex/Vsirtm1Lex
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal T cell activation J:222944
increased IgA level J:222944
increased IgM level J:222944
increased inflammatory response J:222944
increased interferon-gamma secretion J:222944
increased interleukin-17 secretion J:222944
Vsirtm1Lex/Vsirtm1Lex
Tg(Tcra2D2,Tcrb2D2)1Kuch/0

(involves: 129S5/SvEvBrd * C57BL/6)
increased susceptibility to experimental autoimmune encephalomyelitis J:222944
Vstm5em1Cdj/Vstm5em1Cdj
(Not Specified)
decreased interleukin-2 secretion J:267548
immune system phenotype J:267548
Vtcn1tm1Lpc/Vtcn1tm1Lpc
(B6.129S-Vtcn1tm1Lpc)
abnormal myelopoiesis J:145712
decreased susceptibility to bacterial infection J:145712
decreased susceptibility to bacterial infection induced morbidity/mortality J:145712
increased neutrophil cell number J:145712
Vtcn1tm1Mak/Vtcn1tm1Mak
(C.Cg-Vtcn1tm1Mak)
decreased interleukin-4 secretion J:112130
decreased susceptibility to parasitic infection J:112130
increased interferon-gamma secretion J:112130
Vtcn1tm1Xxz/Vtcn1tm1Xxz
(involves: 129S4/SvJae * BALB/c * C57BL/6)
increased CD4-positive, alpha-beta T cell number J:177612
increased interleukin-17 secretion J:177612
increased susceptibility to autoimmune diabetes J:177612
increased susceptibility to experimental autoimmune encephalomyelitis J:177612
increased T-helper 1 cell number J:177612
increased T-helper 17 cell number J:177612
Vwftm1.1Geno/Vwf+
(involves: C57BL/6)
increased acute inflammation J:250145
Vwftm1.1Geno/Vwftm1.1Geno
(involves: C57BL/6)
increased acute inflammation J:250145
Vwftm1Wgr/Vwftm1Wgr
(B6.129S2-Vwftm1Wgr)
increased susceptibility to bacterial infection J:140334
increased susceptibility to experimental autoimmune encephalomyelitis J:140334
Wactm2b(EUCOMM)Wtsi/Wac+
(C57BL/6N-Wactm2b(EUCOMM)Wtsi/Wtsi)
decreased eosinophil cell number J:211773
increased Ly6C low monocyte number J:211773
increased monocyte cell number J:211773
Wastm1Itl/Y
(Not Specified)
abnormal dendritic cell morphology J:153247
abnormal dendritic cell physiology J:153247
abnormal lymphocyte morphology J:153247
decreased NK cell number J:153247
decreased T cell number J:153247
decreased T cell proliferation J:153247
increased anti-double stranded DNA antibody level J:153247
increased B cell number J:153247
increased follicular B cell number J:153247
increased leukocyte cell number J:153247
increased splenocyte number J:153247
spleen hyperplasia J:153247
Wastm1Itl/Wastm1Itl
(Not Specified)
abnormal dendritic cell morphology J:153247
abnormal dendritic cell physiology J:153247
abnormal lymphocyte morphology J:153247
decreased NK cell number J:153247
decreased T cell number J:153247
decreased T cell proliferation J:153247
increased anti-double stranded DNA antibody level J:153247
increased B cell number J:153247
increased follicular B cell number J:153247
increased leukocyte cell number J:153247
increased splenocyte number J:153247
spleen hyperplasia J:153247
Wastm1Kas/Wastm1Kas
(involves: 129/Sv * C57BL/6)
decreased B cell number J:87875
decreased double-positive T cell number J:87875
decreased lymphocyte cell number J:87875
decreased T cell number J:87875
lymphoid hypoplasia J:87875
thymus hypoplasia J:87875
Wastm1Sbs/Y
(involves: 129S6/SvEvTac)
abnormal dendritic cell morphology J:153247
abnormal dendritic cell physiology J:153247
abnormal lymphocyte morphology J:153247
decreased NK cell number J:153247
decreased T cell number J:153247
decreased T cell proliferation J:153247
increased anti-double stranded DNA antibody level J:153247
increased B cell number J:153247
increased follicular B cell number J:153247
increased leukocyte cell number J:153247
increased monocyte cell number J:153247
increased splenocyte number J:153247
spleen hyperplasia J:153247
Wastm1Sbs/Y
(involves: 129S6/SvEvTac * C57BL/6)
abnormal B cell physiology J:182528
decreased marginal zone B cell number J:182528
decreased mature B cell number J:182528
increased anti-chromatin antibody level J:182528
increased anti-double stranded DNA antibody level J:182528
increased anti-single stranded DNA antibody level J:182528
increased autoantibody level J:182528
increased germinal center B cell number J:182528
increased IgA level J:182528
increased IgE level J:182528
increased IgM level J:182528
increased plasma cell number J:182528
Wastm1Sbs/Wastm1Sbs
(either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6))
colitis J:48836
decreased B cell number J:48836
decreased lymphocyte cell number J:48836
decreased T cell number J:48836
decreased T cell proliferation J:48836
immune system phenotype J:48836
increased neutrophil cell number J:48836
Wastm1Sbs/Wastm1Sbs
(involves: C57BL/6 * CBA)
abnormal B cell physiology J:95909
Wastm1Sbs/Wastm1Sbs
(involves: 129S/SvEv)
abnormal cytokine secretion J:86835
abnormal mast cell morphology J:86835
abnormal mast cell physiology J:86835
abnormal osteoclast differentiation J:90542
abnormal osteoclast physiology J:90542
Wastm1Sbs/Wastm1Sbs
(involves: BALB/c)
abnormal dendritic cell antigen presentation J:84131
decreased T cell proliferation J:84131
immune system phenotype J:84131
Wastm1Sbs/Wastm1Sbs
(involves: 129S6/SvEvTac)
abnormal dendritic cell morphology J:153247
abnormal dendritic cell physiology J:153247
abnormal double-negative T cell morphology J:125309
abnormal double-positive T cell morphology J:125309
abnormal lymphocyte morphology J:153247
abnormal thymocyte activation J:125309
decreased NK cell number J:153247
decreased T cell number J:153247
decreased T cell proliferation J:153247
increased anti-double stranded DNA antibody level J:153247
increased B cell number J:153247
increased follicular B cell number J:153247
increased leukocyte cell number J:153247
increased monocyte cell number J:153247
increased splenocyte number J:153247
spleen hyperplasia J:153247
Wastm1Sbs/Wastm1Sbs
(129S6/SvEvTac-Wastm1Sbs/J)
glomerulonephritis J:180407
increased IgA level J:180407
increased IgM level J:180407
Wastm1Sbs/Wastm1Sbs
(involves: 129S6/SvEvTac * C57BL/6)
abnormal B cell physiology J:182528
decreased marginal zone B cell number J:182528
decreased mature B cell number J:182528
increased anti-chromatin antibody level J:182528
increased anti-double stranded DNA antibody level J:182528
increased anti-single stranded DNA antibody level J:182528
increased autoantibody level J:182528
increased germinal center B cell number J:182528
increased IgA level J:182528
increased IgE level J:182528
increased IgM level J:182528
increased plasma cell number J:182528
Wastm1Sbs/Wastm1Sbs
Wasltm2Sbs/Wasltm2Sbs
Tg(Lck-cre)1Cwi/?

(involves: 129S6/SvEvTac * C57BL/6)
abnormal double-negative T cell morphology J:125309
abnormal double-positive T cell morphology J:125309
abnormal thymocyte activation J:125309
colitis J:125309
decreased regulatory T cell number J:125309
decreased single-positive T cell number J:125309
decreased T cell number J:125309
decreased thymocyte number J:125309
increased single-positive T cell number J:125309
Wastm2Itl/Y
(Not Specified)
abnormal dendritic cell morphology J:153247
abnormal dendritic cell physiology J:153247
abnormal lymphocyte morphology J:153247
decreased NK cell number J:153247
decreased T cell number J:153247
decreased T cell proliferation J:153247
increased anti-double stranded DNA antibody level J:153247
increased B cell number J:153247
increased follicular B cell number J:153247
increased leukocyte cell number J:153247
increased splenocyte number J:153247
Wastm2Itl/Wastm2Itl
(Not Specified)
abnormal dendritic cell morphology J:153247
abnormal dendritic cell physiology J:153247
abnormal lymphocyte morphology J:153247
decreased NK cell number J:153247
decreased T cell number J:153247
decreased T cell proliferation J:153247
increased anti-double stranded DNA antibody level J:153247
increased B cell number J:153247
increased follicular B cell number J:153247
increased leukocyte cell number J:153247
increased splenocyte number J:153247
Wasltm1.1Ttha/Wasltm1.1Ttha
Tg(KRT14-cre)1Amc/0

(involves: C57BL/6 * C57BL/6N * CBA)
abnormal circulating chemokine level J:271857
dermatitis J:271857
increased circulating interleukin-1 alpha level J:271857
increased circulating interleukin-6 level J:271857
increased circulating interleukin-17 level J:271857
increased circulating tumor necrosis factor level J:271857
increased susceptibility to bacterial infection J:271857
skin inflammation J:271857
Wbcq1C57BLKS/J/Wbcq1C57BLKS/J
(involves: C57BLKS/J * SM/J)
increased leukocyte cell number J:102636
Wbcq1C57BLKS/J/Wbcq1SM/J
(involves: C57BLKS/J * SM/J)
increased leukocyte cell number J:102636
Wbcq2C57BLKS/J/Wbcq2SM/J
(involves: C57BLKS/J * SM/J)
increased leukocyte cell number J:102636
Wbcq2C57BLKS/J/Wbcq2SM/J
Wbcq3C57BLKS/J/Wbcq3C57BLKS/J

(involves: C57BLKS/J * SM/J)
increased leukocyte cell number J:102636
Wbcq2SM/J/Wbcq2SM/J
(involves: C57BLKS/J * SM/J)
increased leukocyte cell number J:102636
Wbcq2SM/J/Wbcq2SM/J
Wbcq3C57BLKS/J/Wbcq3C57BLKS/J

(involves: C57BLKS/J * SM/J)
increased leukocyte cell number J:102636
Wbcq3C57BLKS/J/Wbcq3SM/J
(involves: C57BLKS/J * SM/J)
increased leukocyte cell number J:102636
Wbcq3SM/J/Wbcq3SM/J
(involves: C57BLKS/J * SM/J)
increased leukocyte cell number J:102636
Wbcq4NZW/LacJ/Wbcq4NZW/LacJ
(involves: NZW/LacJ * SM/J)
increased leukocyte cell number J:102636
Wbcq4NZW/LacJ/Wbcq4SM/J
(involves: NZW/LacJ * SM/J)
increased leukocyte cell number J:102636
Wbcq5NZW/LacJ/Wbcq5NZW/LacJ
(involves: NZW/LacJ * SM/J)
increased leukocyte cell number J:102636
Wbcq6NZW/LacJ/Wbcq6NZW/LacJ
(involves: NZW/LacJ * SM/J)
increased leukocyte cell number J:102636
Wbcq6SM/J/Wbcq6SM/J
(involves: NZW/LacJ * SM/J)
increased leukocyte cell number J:102636
Wbp1ltm2a(EUCOMM)Hmgu/Wbp1ltm2a(EUCOMM)Hmgu
(involves: C57BL/6N)
abnormal pre-B cell morphology J:284781
decreased B cell number J:284781
decreased B-1 B cell number J:284781
decreased pre-B cell number J:284781
decreased pro-B cell number J:284781
immune system phenotype J:284781
increased dendritic cell number J:284781
increased marginal zone B cell number J:284781
Wbp2tm2a(EUCOMM)Wtsi/Wbp2tm2a(EUCOMM)Wtsi
(C57BL/6N-Wbp2tm2a(EUCOMM)Wtsi/Cnrm)
increased leukocyte cell number J:165965
Wbp11em1Gcha/Wbp11+
(involves: C57BL/6J * FVB/N)
ectopic thymus J:300837
Wdfy3em1(IMPC)Mbp/Wdfy3+
(C57BL/6N-Wdfy3em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Wdfy4em1Jkln/Wdfy4em1Jkln
(C57BL/6J-Wdfy4em1Jkln)
decreased dendritic cell number J:326216
immune system phenotype J:326216
Wdr1Gt(XN462)Byg/Wdr1rede
(involves: 129P2/OlaHsd * C57BL/6)
ear inflammation J:134092
skin inflammation J:134092
Wdr1rede/Wdr1rede
(Not Specified)
increased inflammatory response J:85113
Wdr1rede/Wdr1rede
(C57BL/6-Wdr1rede)
abnormal myelopoiesis J:134092
abnormal osteoclast physiology J:134092
abnormal thrombopoiesis J:134092
ear inflammation J:134092
impaired neutrophil chemotaxis J:134092
increased neutrophil cell number J:134092
increased osteoclast cell number J:134092
skin inflammation J:134092
Wdr27em1(IMPC)Ccpcz/Wdr27em1(IMPC)Ccpcz
(C57BL/6NCrl-Wdr27em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Wdr37tm1a(KOMP)Wtsi/Wdr37tm1a(KOMP)Wtsi
(C57BL/6N-Wdr37tm1a(KOMP)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Wdr41m1Btlr/Wdr41m1Btlr
(C57BL/6J-Wdr41m1Btlr)
increased CD4-positive, alpha-beta T cell number J:268243
increased CD8-positive, alpha-beta T cell number J:268243
increased circulating interleukin-12b level J:268243
increased susceptibility to induced colitis J:268243
increased tumor necrosis factor secretion J:268243
Wdr41m2Btlr/Wdr41m2Btlr
(C57BL/6J-Wdr41m2Btlr)
increased CD4-positive, alpha-beta T cell number J:268243
increased CD8-positive, alpha-beta T cell number J:268243
increased tumor necrosis factor secretion J:268243
Wdr45em1Wrst/Y
(involves: C57BL/6N * FVB)
increased leukocyte cell number J:307284
Wdr59tm1b(EUCOMM)Wtsi/Wdr59+
(C57BL/6N-Wdr59tm1b(EUCOMM)Wtsi/Wtsi)
decreased leukocyte cell number J:211773
Wdr62em1(IMPC)Tcp/Wdr62em1(IMPC)Tcp
(C57BL/6NCrl-Wdr62em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Wdr83tm1Guwo/Wdr83+
(involves: C57BL/6)
kidney inflammation J:153983
Wdr89m1Anu/Wdr89m1Anu
(C57BL/6NCrlAnu-Wdr89m1Anu)
immune system phenotype J:104190
Wfdc1tm1Bcm/Wfdc1tm1Bcm
(involves: 129S7/SvEvBrd * C57BL/6)
decreased susceptibility to Orthomyxoviridae infection J:216357
Wfdc2tm1.1Ohbo/Wfdc2tm1.1Ohbo
(involves: C57BL/6NCrlj * CBA/JNCrlj)
abnormal cytokine level J:282576
lung inflammation J:282576
Whrnwi/Whrnwi
(involves: C57BL/6J * STOCK a Tyrp1b Myo5ad Oca2p Ednrbs)
decreased leukocyte cell number J:5538
decreased thymus weight J:5037
Why1MOLF/EiJ/?
(involves: C57BL/6J * MOLF/Ei)
increased interleukin-6 secretion J:131437
Why2MOLF/EiJ/?
(involves: C57BL/6J * MOLF/Ei)
decreased interleukin-6 secretion J:131437
Wipf1tm1Geha/Wipf1tm1Geha
(involves: 129S6/SvEvTac)
abnormal T cell physiology J:74719
decreased T cell proliferation J:74719
decreased thymocyte number J:74719
increased B cell proliferation J:74719
increased IgE level J:74719
increased IgM level J:74719
thymus hypoplasia J:74719
Wipf1tm1Geha/Wipf1tm1Geha
(involves: 129S6/SvEvTac * C57BL/6)
abnormal alpha-beta T cell morphology J:116168
abnormal lymph node B cell domain morphology J:116168
abnormal lymphopoiesis J:116168
abnormal Peyer's patch T cell area morphology J:116168
abnormal spleen morphology J:116168
abnormal thymus morphology J:116168
colitis J:116168
decreased B cell number J:116168
decreased follicular B cell number J:116168
decreased lymphocyte cell number J:116168
decreased marginal zone B cell number J:116168
decreased spleen white pulp amount J:116168
decreased thymus weight J:116168
enlarged spleen J:116168
glomerulonephritis J:116168
increased autoantibody level J:116168
increased granulocyte number J:116168
increased IgA level J:116168
increased monocyte cell number J:116168
increased spleen red pulp amount J:116168
interstitial pneumonia J:116168
joint inflammation J:116168
lung inflammation J:116168
Wipi1em1(IMPC)Mbp/Wipi1em1(IMPC)Mbp
(C57BL/6NCrl-Wipi1em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Wlstm1.1Arte/Wlstm1.1Arte
Krt14tm1(cre)Wbm/Krt14+

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:202499
abnormal T cell physiology J:202499
abnormal T cell subpopulation ratio J:202499
cutaneous mastocytosis J:202499
decreased double-positive T cell number J:202499
decreased gamma-delta T cell number J:202499
decreased T cell number J:202499
decreased thymus weight J:202499
increased double-negative T cell number J:202499
increased macrophage cell number J:202499
increased neutrophil cell number J:202499
increased T cell proliferation J:202499
skin inflammation J:202499
small thymus medulla J:202499
thymus atrophy J:202499
thymus hypoplasia J:202499
Wlstm1.1Arte/Wlstm1.1Arte
Tg(Foxn1-cre)1Tbo/0

(involves: C57BL/6)
immune system phenotype J:202499
Wnt1tm1Brd/Wnt1tm1Brd
(involves: 129S7/SvEvBrd * C57BL/6J)
decreased thymocyte number J:75999
Wnt1tm1Brd/Wnt1tm1Brd
Wnt4tm1Amc/Wnt4tm1Amc

(involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6J)
decreased thymocyte number J:75999
Wnt2btm1b(EUCOMM)Wtsi/Wnt2btm1b(EUCOMM)Wtsi
(C57BL/6N-Wnt2btm1b(EUCOMM)Wtsi/Tcp)
abnormal spleen morphology J:211773
enlarged spleen J:211773
small spleen J:211773
Wnt4tm1Amc/Wnt4tm1Amc
(involves: 129S1/Sv)
decreased thymocyte number J:75999
Wnt5ab2b3077.1Clo/Wnt5ab2b3077.1Clo
(C57BL/6J-Wnt5ab2b3077.1Clo)
thymus hypoplasia J:175213
Wrnb2b3121.1Clo/Wrnb2b3121.1Clo
(C57BL/6J-Wrnb2b3121.1Clo)
thymus hypoplasia J:175213
Wrntm1Led/Wrntm1Led
(involves: 129S6/SvEvTac * Black Swiss)
heart inflammation J:106446
increased susceptibility to infection J:106446
Wrntm1Lgu/Wrntm1Lgu
(B6J.Cg-Wrntm1Lgu)
increased osteoclast cell number J:213181
Wrnip1tm1a(EUCOMM)Wtsi/Wrnip1tm1a(EUCOMM)Wtsi
(C57BL/6N-Wrnip1tm1a(EUCOMM)Wtsi/Cnrm)
decreased T cell number J:165965
Wt1tm1Jae/Wt1tm1Jae
(involves: 129S4/SvJae * C57BL/6 * MF1)
abnormal spleen development J:56651
absent spleen J:56651
increased splenocyte apoptosis J:56651
Wt1tm1Mlh/Wt1+
(involves: 129P2/OlaHsd * C57BL/6)
glomerulonephritis J:135449
Wt1tm1Mlh/Wt1+
(129P2/OlaHsd-Wt1tm1Mlh)
glomerulonephritis J:135449
Wt1tm1Mlh/Wt1+
(involves: 129P2/OlaHsd * C57BL/6 * MF1)
glomerulonephritis J:135449
Wwc1tm1Arsc/Wwc1tm1Arsc
Wwc2tm1.1Arte/Wwc2tm1.1Arte
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: 129 * C57BL/6 * C57BL/6J * DBA)
liver inflammation J:305034
Wwoxem1Mald/Wwoxem1Mald
(FVB/N-Wwoxem1Mald)
microgliosis J:339564
Wwoxtm1.1Mald/Wwoxtm1.1Mald
(involves: C57BL/6 * FVB/N)
abnormal thymus cortex morphology J:155406
decreased leukocyte cell number J:155406
decreased spleen weight J:155406
decreased thymus weight J:155406
small spleen J:155406
spleen atrophy J:155406
Wwoxtm1Ria/Wwox+
(involves: 129X1/SvJ * C57BL/6)
enlarged spleen J:120064
Wwoxtm1Ria/Wwoxtm1Ria
(involves: 129X1/SvJ * C57BL/6J)
abnormal osteoclast physiology J:138140
Wwp2tm1.1Yyiw/Wwp2tm1.1Yyiw
(involves: 129S/SvEv * C57BL/6 * FVB/N)
immune system phenotype J:228707
increased circulating interferon-beta level J:228707
increased circulating interleukin-6 level J:228707
increased circulating tumor necrosis factor level J:228707
Wwtr1tm1Benj/Wwtr1tm1Benj
(129S6/SvEvTac-Wwtr1tm1Benj)
intestinal inflammation J:125326
lung inflammation J:125326
Wwtr1tm1Benj/Wwtr1tm1Benj
(129S-Wwtr1tm1Benj/J)
intestinal inflammation J:156586
lung inflammation J:156586
Wwtr1tm1Hku/Wwtr1tm1Hku
(involves: 129 * C57BL/6 * ICR)
alveolitis J:164957
lung inflammation J:164957
Wwtr1tm1Whun/Wwtr1tm1Whun
(either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6))
tubular nephritis J:119488
Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
(C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics)
decreased IgG1 level J:165965
decreased T cell number J:165965
Xbp1tm1b(EUCOMM)Wtsi/Xbp1+
(C57BL/6N-Xbp1tm1b(EUCOMM)Wtsi/Ics)
decreased large unstained cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
Xbp1tm2Glm/Xbp1+
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6J * FVB/N * SJL)
small intestinal inflammation J:188627
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Defa6-icre)1Rsb/0

(involves: 129S6/SvEvTac * C57BL/6)
small intestinal inflammation J:206084
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Nes-cre)1Kln/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
decreased susceptibility to prion infection J:131028
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6J * FVB/N * SJL)
increased susceptibility to bacterial infection J:188627
increased susceptibility to induced colitis J:188627
small intestinal inflammation J:188627
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
small intestinal inflammation J:206084
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre/ERT2)23Syr/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
small intestinal inflammation J:206084
Xbp1tm2Glm/Xbp1tm2Glm
Tnfrsf1atm1Imx/Tnfrsf1atm1Imx
Tg(Vil1-cre)997Gum/0

(involves: 129S6/SvEvTac * C57BL/6 * SJL)
small intestinal inflammation J:206084
Xbp1tm3Glm/Xbp1tm3Glm
Tg(Vil1-cre/ERT2)23Syr/0

(involves: 129S6/SvEvTac * C57BL/6 * DBA/2)
small intestinal inflammation J:188627
Xcl1tm1.1Dnax/Xcl1tm1.1Dnax
(either: (involves: 129/Sv * BALB/c) or (involves: 129/Sv * C57BL/6))
abnormal immune system morphology J:176844
autoimmune response J:176844
decreased dendritic cell number J:176844
decreased regulatory T cell number J:176844
heart inflammation J:176844
increased dendritic cell number J:176844
increased inflammatory response J:176844
lacrimal gland inflammation J:176844
liver inflammation J:176844
salivary gland inflammation J:176844
stomach inflammation J:176844
Xcl1tm1Rakr/Xcl1tm1Rakr
(B6.129-Xcl1tm1Rakr)
decreased cytotoxic T cell cytolysis J:155297
immune system phenotype J:155297
Xcl1tm1Rakr/Xcl1tm1Rakr
Tg(TcraTcrb)1100Mjb/0

(involves: 129/Sv * C57BL/6)
abnormal CD8-positive, alpha-beta T cell physiology J:155297
decreased cytotoxic T cell cytolysis J:155297
decreased interferon-gamma secretion J:155297
decreased T cell number J:155297
Xcr1tm1Dgen/Xcr1tm1Dgen
(B6.129P2-Xcr1tm1Dgen/J)
abnormal dendritic cell physiology J:155297
immune system phenotype J:155297
Xcr1tm2(HBEGF/Venus)Ksho/Xcr1+
(involves: C57BL/6 * C57BL/6J)
abnormal antigen presentation J:204851
abnormal CD8-positive, alpha-beta T cell physiology J:204851
decreased dendritic cell number J:204851
decreased interferon-gamma secretion J:204851
decreased susceptibility to bacterial infection J:204851
immune system phenotype J:204851
Xdhtm1.1Takni/Xdhtm1.1Takni
(involves: C57BL/6)
abnormal peritoneal macrophage morphology J:281671
Xdhtm1Fink/Xdhtm1Fink
(involves: 129X1/SvJ * C57BL/6J)
tubulointerstitial nephritis J:166326
Xiaptm1Hs/Xiaptm1Hs
(B6.129P2-Xiaptm1Hs)
immune system phenotype J:138979
Xkrxtm1b(EUCOMM)Wtsi/Xkrxtm1b(EUCOMM)Wtsi
(C57BL/6N-Xkrxtm1b(EUCOMM)Wtsi/Wtsi)
increased anti-nuclear antigen antibody level J:211773
Xpatm1Tnka/Xpatm1Tnka
(involves: C57BL/6 * CBA)
abnormal immune system physiology J:35054
abnormal Langerhans cell physiology J:35054
abnormal lymphocyte physiology J:55739
abnormal NK cell physiology J:55739
increased NK cell number J:55739
Xpnpep1tm1a(KOMP)Wtsi/Xpnpep1tm1a(KOMP)Wtsi
(C57BL/6N-Xpnpep1tm1a(KOMP)Wtsi/Wtsi)
abnormal thymus morphology J:239583
blood in lymph vessels J:239583
increased gamma-delta T cell number J:211773
increased NK cell number J:211773
Xpo5em1(IMPC)Mbp/Xpo5+
(C57BL/6NCrl-Xpo5em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Xpr1Sxv/Xpr1Sxv
(M. spretus)
increased susceptibility to Retroviridae infection J:7951
Xrcc4tm1Fwa/Xrcc4tm1Fwa
(involves: 129P2/OlaHsd * C57BL/6)
thymus hypoplasia J:65218
Xrcc5m1Btlr/Xrcc5m1Btlr
(C57BL/6J-Xrcc5m1Btlr)
abnormal B cell differentiation J:274736
abnormal CD8-positive, alpha-beta T cell differentiation J:274736
abnormal T cell differentiation J:274736
decreased B-2 B cell number J:274736
decreased CD4-positive, alpha-beta T cell number J:274736
decreased CD8-positive, alpha-beta T cell number J:274736
decreased CD8-positive, naive alpha-beta T cell number J:274736
decreased T cell number J:274736
increased B-1a cell number J:274736
increased B-1b cell number J:274736
increased CD4-positive, alpha-beta T cell number J:274736
increased dendritic cell number J:274736
increased effector memory CD4-positive, alpha-beta T cell number J:274736
increased effector memory CD8-positive, alpha-beta T cell number J:274736
increased neutrophil cell number J:274736
Xrcc5tm1Dbr/Xrcc5tm1Dbr
(involves: 129S1/Sv * C57BL/6)
abnormal B cell differentiation J:34834
absent T cells J:34834
arrested B cell differentiation J:34834
arrested T cell differentiation J:34834
increased double-negative T cell number J:34834
lymph node hypoplasia J:34834
thymus hypoplasia J:34834
Xrcc5tm1Dbr/Xrcc5tm1Dbr
Lig4tm1Fwa/Lig4tm1Fwa

(involves: 129S6/SvEvTac * C57BL/6)
abnormal lymphocyte morphology J:80467
Xrcc5tm1Nus/Xrcc5tm1Nus
(involves: 129S1/Sv * 129X1/SvJ)
abnormal class switch recombination J:120658
abnormal humoral immune response J:120658
spleen hypoplasia J:108657
thymus hypoplasia J:108657
Xrcc6avon/Xrcc6avon
(involves: C57BL/6JAnu)
decreased B cell number J:104190
decreased T cell number J:104190
Xrcc6tm1Fwa/Xrcc6tm1Fwa
(involves: 129S6/SvEvTac * C57BL/6J)
abnormal B cell differentiation J:44361
abnormal B cell morphology J:44361
abnormal T cell differentiation J:44361
abnormal T cell morphology J:44361
absent immature B cells J:44361
absent mature B cells J:44361
absent pre-B cells J:44361
arrested B cell differentiation J:44361
decreased IgM level J:44361
decreased single-positive T cell number J:44361
decreased thymocyte number J:44361
increased double-positive T cell number J:44361
Xrcc6tm1Gcl/Xrcc6tm1Gcl
(involves: 129S1/Sv * C57BL/6)
abnormal B cell differentiation J:108657
abnormal immune system organ morphology J:108657
absent mature B cells J:108657
decreased spleen white pulp amount J:108657
small lymph nodes J:108657
small spleen J:108657
small thymus J:108657
spleen hypoplasia J:108657
thymus hypoplasia J:108657
Xylt1npo/Xylt1npo
(involves: C57BL/6J * FVB/NJ)
abnormal osteoclast differentiation J:205339
X/Yaa
((NZB x BXSB)F1)
abnormal immune cell physiology J:6235
abnormal lymph node morphology J:6235
enlarged lymph nodes J:6235
increased anti-erythrocyte antigen antibody level J:6235
increased anti-nuclear antigen antibody level J:6235
increased autoantibody level J:6235
increased spleen weight J:6235
increased susceptibility to autoimmune disorder J:6235
X/Yaa
((SJL/J x BXSB)F1)
enlarged lymph nodes J:6235
increased susceptibility to autoimmune disorder J:6235
X/Yaa
((C57BL/6J x BXSB)F1)
enlarged lymph nodes J:6235
increased susceptibility to autoimmune disorder J:6235
X/Yaa
(involves: BXSB * NZB)
enlarged lymph nodes J:6235
increased susceptibility to autoimmune disorder J:6235
X/Yaa
(BXSB/MpJ)
abnormal B cell differentiation J:108760
abnormal lymph node morphology J:6235
abnormal spleen B cell follicle morphology J:179430
abnormal T cell subpopulation ratio J:179430
enlarged lymph nodes J:6235
glomerulonephritis J:6235
increased anti-erythrocyte antigen antibody level J:6235
increased anti-nuclear antigen antibody level J:179430
increased circulating interleukin-21 level J:93740
increased IgG1 level J:179430, J:93740
increased IgG2a level J:179430
increased IgG2b level J:179430
increased IgG3 level J:93740
increased monocyte cell number J:7308
increased plasma cell number J:108760
increased spleen weight J:6235
increased splenocyte number J:179430
increased susceptibility to autoimmune disorder J:108760, J:6235
X/Yaa
((NZW x SB)F1)
abnormal immune serum protein physiology J:7276
glomerulonephritis J:7276
increased susceptibility to autoimmune disorder J:7276
X/Yaa
((NZW x BXSB)F1)
abnormal immune serum protein physiology J:7276
increased susceptibility to autoimmune disorder J:7276
X/Yaa
(BXSB/MpJScr)
decreased CD4-positive, alpha-beta T cell number J:10973
glomerulonephritis J:10973
increased anti-nuclear antigen antibody level J:10973
increased IgG level J:10973
increased monocyte cell number J:10973
increased susceptibility to autoimmune disorder J:10973
X/Yaa
((NZB x B6.SB/Le-Yaa)F1)
increased monocyte cell number J:129409
X/Yaa
(B6.SB-Yaa/J)
decreased marginal zone B cell number J:127600
increased splenocyte proliferation J:127600
Yaa2BXSB/J/?
(involves: BXSB/J * C57BL/10Ola)
kidney inflammation J:49868
Yaa3BXSB/J/?
(involves: BXSB/J * C57BL/10Ola)
kidney inflammation J:49868
Yaa4BXSB/J/?
(involves: BXSB/J * C57BL/10Ola)
kidney inflammation J:49868
YaailNZW/Ola/?
(involves: C57BL/6Ola * NZW/Ola)
glomerulonephritis J:52110
increased anti-double stranded DNA antibody level J:52110
Yap1M1Btlr/Yap1M1Btlr
(C57BL/6J-Yap1M1Btlr)
increased susceptibility to induced colitis J:267549
Yap1tm1.1Dupa/Yap1tm1.1Dupa
Tg(Vil1-cre)997Gum/0

(involves: 129P2/OlaHsd * C57BL/6J * SJL)
increased susceptibility to induced colitis J:165471
Ydjctm1(KOMP)Wtsi/Ydjctm1(KOMP)Wtsi
(C57BL/6N-Ydjctm1(KOMP)Wtsi/Wtsi)
increased effector memory T-helper cell number J:211773
increased germinal center B cell number J:211773
Yeats4em1Zfa/Yeats4em1Zfa
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6 * C57BL/10 * CBA/Ca)
abnormal acute inflammation J:282740
abnormal gut-associated lymphoid tissue morphology J:282740
abnormal interleukin secretion J:282740
abnormal lymphocyte physiology J:282740
abnormal lymphopoiesis J:282740
decreased interferon-gamma secretion J:282740
decreased interleukin-5 secretion J:282740
decreased interleukin-12 secretion J:282740
decreased lymphocyte cell number J:282740
decreased Peyer's patch number J:282740
increased susceptibility to bacterial infection J:282740
Yipf6em1(IMPC)Mbp/Yipf6em1(IMPC)Mbp
(C57BL/6N-Yipf6em1(IMPC)Mbp/MbpMmucd)
increased monocyte cell number J:211773
Yipf6M1Btlr/Y
(C57BL/6J-Yipf6M1Btlr/Mmucd)
colitis J:187584
increased susceptibility to induced colitis J:187584
Yipf6M1Btlr/Yipf6M1Btlr
(C57BL/6J-Yipf6M1Btlr/Mmucd)
colitis J:187584
increased susceptibility to induced colitis J:187584
Ykt6em1(IMPC)J/Ykt6+
(C57BL/6NJ-Ykt6em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Yod1tm1bNarl/Yod1tm1bNarl
(C57BL/6N-Yod1tm1bNarl/Narl)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Ythdf3em1(IMPC)Mbp/Ythdf3em1(IMPC)Mbp
(C57BL/6N-Ythdf3em1(IMPC)Mbp/MbpMmucd)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Ythdf3em1Caox/Ythdf3em1Caox
(involves: C57BL/6J)
abnormal macrophage physiology J:276397
decreased susceptibility to Riboviria infection J:276397
decreased susceptibility to Riboviria infection induced morbidity/mortality J:276397
immune system phenotype J:276397
Ywhaztm1b(EUCOMM)Hmgu/Ywhaz+
(C57BL/6N-Ywhaztm1b(EUCOMM)Hmgu/Tcp)
enlarged lymph nodes J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Yy1tm3.1Yshi/Yy1+
(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J)
immune system phenotype J:208226
Yy2em1(IMPC)Mbp/Yy2em1(IMPC)Mbp
(C57BL/6NCrl-Yy2em1(IMPC)Mbp/Mmucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Zap70m1Btlr/Zap70m1Btlr
(involves: C57BL/6J)
abnormal class switch recombination J:185495
abnormal humoral immune response J:167119
absent CD4-positive, alpha-beta T cells J:167119
absent CD8-positive, alpha-beta T cells J:167119
decreased IgG level J:185495
decreased T cell number J:185495
immune system phenotype J:167119, J:185495
Zap70m1Saka/Zap70m1Saka
(involves: BALB/c)
abnormal lymph node cell ratio J:154166
abnormal positive T cell selection J:154166, J:86607
abnormal splenic cell ratio J:154166
abnormal T cell clonal deletion J:154166
abnormal T cell differentiation J:86607
abnormal T cell selection J:86607
abnormal thymocyte activation J:154166
abnormal thymus cell ratio J:154166
chronic joint inflammation J:86607
decreased CD4-positive, alpha-beta T cell number J:154166, J:86607
decreased CD8-positive, alpha-beta T cell number J:154166, J:86607
decreased interleukin-2 secretion J:154166
decreased regulatory T cell number J:154166
decreased T cell proliferation J:154166, J:86607
increased activated T cell number J:154166
increased autoantibody level J:86607
increased B cell number J:86607
increased immunoglobulin level J:86607
increased interleukin-17 secretion J:154166
increased memory T cell number J:154166
increased susceptibility to induced arthritis J:154166
lung inflammation J:86607
rheumatoid arthritis J:86607
Zap70m1Saka/Zap70m1Saka
Tg(DO11.10)10Dlo/0

(involves: BALB/c * C3H * C57BL/6)
decreased T cell number J:86607
decreased T cell proliferation J:86607
Zap70m1Saka/Zap70m1Saka
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: BALB/c * C57BL/6J * DBA/2J)
abnormal positive T cell selection J:86607
arthritis J:86607
Zap70m1Saka/Zap70tm1Dlo
(involves: 129P2/OlaHsd * BALB/c)
arthritis J:86607
Zap70m1Saka/Zap70tm2.1Weis
(involves: 129S4/SvJae * BALB/c)
abnormal T cell clonal deletion J:154166
decreased susceptibility to induced arthritis J:154166
Zap70m2Btlr/Zap70m2Btlr
(involves: C57BL/6J)
decreased T cell number J:174837
Zap70m3Btlr/Zap70m3Btlr
(C57BL/6J-Zap70m3Btlr)
decreased IgG level J:225043
impaired humoral immune response J:225043
Zap70m4Btlr/Zap70m4Btlr
(C57BL/6J-Zap70m4Btlr)
decreased CD4-positive, alpha-beta T cell number J:236698
decreased CD8-positive, alpha-beta T cell number J:236698
decreased T cell number J:236698
Zap70m5Btlr/Zap70m5Btlr
(C57BL/6J-Zap70m5Btlr)
abnormal humoral immune response J:254830
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254830
decreased CD8-positive, alpha-beta T cell number J:254830
decreased CD8-positive, naive alpha-beta T cell number J:254830
decreased IgG level J:254830
increased B cell number J:254830
increased central memory CD4-positive, alpha-beta T cell number J:254830
increased central memory CD8 positive, alpha-beta T cell number J:254830
increased effector memory CD4-positive, alpha-beta T cell number J:254830
Zap70m6Btlr/Zap70m6Btlr
(C57BL/6J-Zap70m6Btlr)
abnormal humoral immune response J:254831
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254831
decreased CD8-positive, alpha-beta T cell number J:254831
decreased CD8-positive, naive alpha-beta T cell number J:254831
decreased IgG level J:254831
increased B cell number J:254831
increased central memory CD4-positive, alpha-beta T cell number J:254831
increased central memory CD8 positive, alpha-beta T cell number J:254831
increased effector memory CD4-positive, alpha-beta T cell number J:254831
Zap70m6Hefl/Zap70m6Hefl
(C3HeB/FeJ-Zap70m6Hefl)
abnormal humoral immune response J:137446
abnormal T cell differentiation J:137446
decreased CD4-positive, alpha-beta T cell number J:137446
decreased CD8-positive, alpha-beta T cell number J:137446
decreased T cell number J:137446
immune system phenotype J:137446
increased IgE level J:137446
increased IgG1 level J:137446
Zap70m6Hefl/Zap70tm1Weis
(involves: 129X1/SvJ * C3HeB/FeJ * C57BL/10 * DBA/2)
decreased T cell number J:137446
increased IgE level J:137446
Zap70m7Btlr/Zap70m7Btlr
(C57BL/6J-Zap70m7Btlr)
abnormal humoral immune response J:254832
decreased IgG level J:254832
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:254832
increased central memory CD8 positive, alpha-beta T cell number J:254832
Zap70m8Btlr/Zap70m8Btlr
(C57BL/6J-Zap70m8Btlr)
decreased CD8-positive, naive alpha-beta T cell number J:272864
increased central memory CD8 positive, alpha-beta T cell number J:272864
Zap70mrtle/Zap70mrtle
(C57BL/6JSfdAnu-Zap70mrtle/Apb)
abnormal positive T cell selection J:104190
abnormal T cell subpopulation ratio J:104190
absent T cells J:104190
arrested T cell differentiation J:104190
decreased T cell number J:104190
Zap70mrtle/Zap70mrtle
(involves: C57BL/6JSfdAnu)
abnormal double-positive T cell morphology J:211510
abnormal regulatory T cell number J:211510
decreased CD4-positive, alpha-beta T cell number J:211510
decreased CD8-positive, alpha-beta T cell number J:211510
increased double-positive T cell number J:211510
Zap70mrtle/Zap70rps
(involves: C57BL/6 * C57BL/6JSfdAnu)
abnormal CD4-positive, alpha beta T cell morphology J:211510
abnormal double-positive T cell morphology J:211510
abnormal regulatory T cell number J:211510
decreased CD4-positive, alpha-beta T cell number J:211510
decreased CD8-positive, alpha-beta T cell number J:211510
increased double-positive T cell number J:211510
Zap70mur/Zap70mur
(C57BL/6Apb-Zap70mur/ApbH)
abnormal T cell activation J:104190
abnormal T cell physiology J:104190
decreased T cell number J:104190
increased IgG2b level J:104190
Zap70st/Zap70st
(involves: C57BL/6)
abnormal T cell physiology J:41170
arrested T cell differentiation J:41170
decreased T cell number J:41170
thymus hypoplasia J:41170
Zap70st/Zap70tm1Dlo
(involves: C57BL/6)
arrested T cell differentiation J:41170
Zap70tm1.1Mmal/Zap70tm1.1Mmal
(B6.129P2-Zap70tm1.1Mmal)
immune system phenotype J:71099
Zap70tm1.1Mmal/Zap70tm1.1Mmal
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6J * DBA/2J)
immune system phenotype J:71099
Zap70tm1.1Mmal/Zap70tm1.1Mmal
Tg(TcrLCMV)327Sdz/0

(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * DBA/2)
abnormal cytokine secretion J:71099
abnormal T cell proliferation J:71099
immune system phenotype J:71099
Zap70tm1Dlo/Zap70tm1Dlo
(involves: 129P2/OlaHsd)
increased double-positive T cell number J:97610
Zap70tm1Weis/Zap70tm1Weis
(involves: 129X1/SvJ * C57BL/6J)
abnormal lymph node cell ratio J:74974
abnormal splenic cell ratio J:74974
abnormal T cell differentiation J:74974
arrested T cell differentiation J:74974
small lymph nodes J:74974
Zap70tm2.1Mmal/Zap70tm2.1Mmal
(B6.129P2-Zap70tm2.1Mmal)
immune system phenotype J:71099
Zap70tm2.1Mmal/Zap70tm2.1Mmal
Tg(TcraH-Y,TcrbH-Y)71Vbo/0

(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6J * DBA/2J)
abnormal lymph node cell ratio J:71099
abnormal T cell morphology J:71099
abnormal thymus cell ratio J:71099
immune system phenotype J:71099
Zap70tm2.1Mmal/Zap70tm2.1Mmal
Tg(TcrLCMV)327Sdz/0

(involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * DBA/2)
abnormal T cell morphology J:71099
immune system phenotype J:71099
Zap70tm2.1Weis/Zap70tm2.1Weis
(B6.129S4-Zap70tm2.1Weis)
abnormal CD8-positive, alpha-beta T cell differentiation J:154166
abnormal thymus cell ratio J:154166
decreased CD4-positive, alpha-beta T cell number J:154166
decreased CD8-positive, alpha-beta T cell number J:154166
Zap70tm2.1Weis/Zap70tm2.1Weis
(C.129S4-Zap70tm2.1Weis)
abnormal lymph node cell ratio J:154166
abnormal positive T cell selection J:154166
abnormal regulatory T cell physiology J:154166
abnormal splenic cell ratio J:154166
abnormal T cell clonal deletion J:154166
abnormal thymocyte activation J:154166
abnormal thymus cell ratio J:154166
decreased CD4-positive, alpha-beta T cell number J:154166
decreased CD8-positive, alpha-beta T cell number J:154166
decreased interleukin-2 secretion J:154166
decreased regulatory T cell number J:154166
decreased T cell proliferation J:154166
immune system phenotype J:154166
increased activated T cell number J:154166
increased interleukin-17 secretion J:154166
increased memory T cell number J:154166
Zap70tm2.1Weis/Zap70tm2.1Weis
Tg(DO11.10)10Dlo/?

(involves: 129S4/SvJae * BALB/c * C3H * C57BL/6)
abnormal positive T cell selection J:154166
Zap70tm2.1Weis/Zap70tm2.1Weis
Tg(TcraH-Y,TcrbH-Y)71Vbo/?

(involves: 129S4/SvJae * C57BL/6J * DBA/2J)
abnormal positive T cell selection J:154166
abnormal T cell clonal deletion J:154166
Zbed4tm1.1(KOMP)Mbp/Zbed4+
(C57BL/6N-Zbed4tm1.1(KOMP)Mbp/Ucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Zbp1tm1.1Jreh/Zbp1tm1.1Jreh
(involves: C57BL/6 * C57BL/6N)
increased susceptibility to Herpesvirales infection J:252669
Zbp1tm1Aki/Zbp1tm1Aki
(involves: C57BL/6)
immune system phenotype J:132662
Zbtb1m1Btlr/Zbtb1m1Btlr
(involves: C3H/HeN * C57BL/6J)
abnormal B cell differentiation J:178820
abnormal immune system physiology J:178820
abnormal T cell differentiation J:178820
abnormal thymus morphology J:178820
decreased B cell number J:178820
decreased CD4-positive, alpha-beta T cell number J:178820
decreased CD8-positive, alpha-beta T cell number J:178820
decreased DN2 thymocyte number J:178820
decreased DN3 thymocyte number J:178820
decreased DN4 thymocyte number J:178820
decreased double-positive T cell number J:178820
decreased follicular B cell number J:178820
decreased NK cell number J:178820
decreased T cell number J:178820
decreased transitional stage B cell number J:178820
immune system phenotype J:178820
increased B cell number J:178820
thymus hypoplasia J:178820
Zbtb1m2Btlr/Zbtb1m2Btlr
(C57BL/6J-Zbtb1m2Btlr)
abnormal CD8-positive, alpha-beta T cell differentiation J:272845
increased central memory CD8 positive, alpha-beta T cell number J:272845
Zbtb7atm1Ppp/Zbtb7atm1Ppp
(B6.129S1-Zbtb7atm1Ppp)
abnormal lymphopoiesis J:121576
abnormal response to transplant J:121576
decreased B cell number J:121576
decreased pro-B cell number J:121576
Zbtb7atm1Ppp/Zbtb7atm2Ppp
Tg(Mx1-cre)1Cgn/0

(involves: 129S1/Sv * C57BL/6 * CBA)
abnormal B cell differentiation J:121576
abnormal double-positive T cell morphology J:121576
abnormal response to transplant J:121576
decreased B cell number J:121576
decreased leukocyte cell number J:121576
immune system phenotype J:121576
Zbtb7bhd/Zbtb7bhd
(involves: 129/Sv * BALB/c * C3H * C57BL/6)
abnormal CD4-positive T cell differentiation J:48734
absent CD4-positive, alpha-beta T cells J:48734
increased CD8-positive, alpha-beta T cell number J:48734
Zbtb7bhpls/Zbtb7bhpls
(involves: C57BL/6JAnu)
abnormal humoral immune response J:104190
decreased CD4-positive, alpha-beta T cell number J:104190
Zbtb7btm1.1Rbo/Zbtb7btm1.1Rbo
(Not Specified)
abnormal CD8-positive, alpha-beta T cell number J:141145
abnormal T cell differentiation J:141145
decreased CD4-positive, alpha-beta T cell number J:141145
Zbtb7btm1.1Skok/Zbtb7btm1.1Skok
(involves: 129/Sv * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:169841
Zbtb7btm1Itan/Zbtb7btm1Tani
(involves: 129 * C57BL/6)
abnormal CD4-positive, alpha beta T cell morphology J:141142
abnormal CD4-positive, alpha-beta T cell physiology J:141142
decreased CD4-positive, alpha-beta T cell number J:141142
increased CD8-positive, alpha-beta T cell number J:141142
increased double-negative T cell number J:141142
Zbtb7btm1Itan/Zbtb7btm2Itan
(involves: 129 * C57BL/6)
decreased CD4-positive, alpha-beta T cell number J:141142
increased CD8-positive, alpha-beta T cell number J:141142
increased double-negative T cell number J:141142
Zbtb7btm1Litt/Zbtb7btm1.2Litt
(involves: C57BL/6)
abnormal double-positive T cell morphology J:141144
decreased CD4-positive, alpha-beta T cell number J:141144
increased CD8-positive, alpha-beta T cell number J:141144
increased interferon-gamma secretion J:141144
Zbtb7btm1Tani/Zbtb7btm1Tani
(involves: 129 * C57BL/6)
increased double-negative T cell number J:141142
Zbtb7btm2Litt/Zbtb7btm1.2Litt
(involves: 129P2/OlaHsd)
decreased CD4-positive, alpha-beta T cell number J:141144
Zbtb7btm2Litt/Zbtb7btm1.2Litt
Tg(Lck-cre)1Cwi/?

(involves: 129P2/OlaHsd * C57BL/6)
abnormal T cell differentiation J:141144
decreased CD4-positive, alpha-beta T cell number J:141144
Zbtb7btm2Litt/Zbtb7btm2Litt
(involves: 129P2/OlaHsd * C57BL/6 * FVB/N)
absent CD4-positive, alpha-beta T cells J:141519
Zbtb7btm2Tani/Zbtb7b+
(Not Specified)
decreased CD8-positive, alpha-beta T cell number J:131081
Zbtb7btm4.1Itan/Zbtb7btm4.1Itan
(Not Specified)
decreased CD4-positive, alpha-beta T cell number J:193321
increased CD8-positive, alpha-beta T cell number J:193321
Zbtb7btm6.1Itan/Zbtb7btm6.1Itan
Tg(Cd4-cre)1Cwi/?

(involves: C57BL/6 * DBA/2)
decreased CD8-positive, alpha-beta T cell number J:195348
Zbtb7btm6.1Itan/Zbtb7btm6.1Itan
Tg(Cd8a-cre)1Itan/?

(involves: C57BL/6)
immune system phenotype J:195348
Zbtb7btm7Itan/Zbtb7btm7Itan
(Not Specified)
decreased CD4-positive, alpha-beta T cell number J:195348
Zbtb16em1(IMPC)Mbp/Zbtb16em1(IMPC)Mbp
(C57BL/6NCrl-Zbtb16em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Zbtb16lu/Zbtb16lu
(B6.C3-Zbtb16lu/J)
decreased NK T cell number J:139690
Zbtb17tm1Cksn/Zbtb17tm1Cksn
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(B6.Cg-Zbtb17tm1Cksn Commd10Tg(Vav1-icre)A2Kio)
arrested T cell differentiation J:170508
decreased DN1 thymic pro-T cell number J:170508
decreased DN2 thymocyte number J:170508
decreased DN3 thymocyte number J:170508
decreased double-negative T cell number J:170508
decreased gamma-delta T cell number J:170508
decreased T cell number J:170508
decreased thymocyte number J:170508
increased T cell apoptosis J:170508
thymus hypoplasia J:170508
Zbtb17tm1Cksn/Zbtb17tm1Cksn
Tg(Lck-cre)548Jxm/0

(B6.Cg-Zbtb17tm1Cksn Tg(Lck-cre)548Jxm)
immune system phenotype J:170508
Zbtb32tm1Iho/Zbtb32tm1Iho
(involves: BALB/c)
abnormal cytokine secretion J:94944
increased T cell proliferation J:94944
Zbtb32tm1Iho/Zbtb32tm1Iho
(involves: C57BL/6)
increased T cell proliferation J:94944
Zbtb32tm2Ppp/Zbtb32tm2Ppp
(involves: 129S1/Sv)
abnormal cytokine secretion J:95119
increased T cell proliferation J:95119
Zbtb38em1Dbhat/Zbtb38em1Dbhat
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(involves: C57BL/6J * C57BL/6N * C57BL/10 * CBA/Ca)
immune system phenotype J:296556
Zbtb42em1(IMPC)Mbp/Zbtb42em1(IMPC)Mbp
(C57BL/6NCrl-Zbtb42em1(IMPC)Mbp/Mmucd)
enlarged lymph nodes J:211773
Zbtb46tm1(HBEGF)Mnz/Zbtb46+
(C57BL/6-Zbtb46tm1(HBEGF)Mnz)
abnormal memory T cell physiology J:189122
abnormal response to infection J:189122
abnormal T-helper 1 physiology J:189122
decreased dendritic cell number J:189122
immune system phenotype J:189122
increased monocyte cell number J:189122
increased neutrophil cell number J:189122
increased susceptibility to parasitic infection J:189122
Zbtb46tm1Kmm/Zbtb46tm1Kmm
(129S/SvEv-Zbtb46tm1Kmm)
abnormal dendritic cell physiology J:184205
immune system phenotype J:184205
Zbtb46tm2.1Mnz/Zbtb46tm2.1Mnz
(involves: C57BL/6)
abnormal dendritic cell morphology J:191314
abnormal lymphangiogenesis J:191314
decreased dendritic cell number J:191314
enlarged lymph nodes J:191314
increased dendritic cell number J:191314
lymph node hyperplasia J:191314
Zc2hc1cem1(IMPC)Ccpcz/Zc2hc1cem1(IMPC)Ccpcz
(C57BL/6N-Zc2hc1cem1(IMPC)Ccpcz/Ccpcz)
abnormal thymus morphology J:211773
enlarged thymus J:211773
Zc3h7aitem1Caox/Zc3h7aitem1Caox
(C57BL/6J-Zc3h7aitem1Caox)
abnormal interferon secretion J:282488
abnormal macrophage activation involved in immune response J:282488
decreased circulating interferon-alpha level J:282488
decreased circulating interferon-beta level J:282488
decreased circulating interleukin-6 level J:282488
decreased interferon-alpha secretion J:282488
decreased interferon-beta secretion J:282488
decreased interleukin-6 secretion J:282488
immune system phenotype J:282488
increased susceptibility to Riboviria infection J:282488
increased susceptibility to Riboviria infection induced morbidity/mortality J:282488
Zc3h7bem1(IMPC)J/Zc3h7bem1(IMPC)J
(C57BL/6NJ-Zc3h7bem1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Zc3h8em1(IMPC)Ccpcz/Zc3h8+
(C57BL/6N-Zc3h8em1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
decreased CD8-positive, naive alpha-beta T cell number J:211773
enlarged spleen J:211773
Zc3h11aem1(IMPC)Mbp/Zc3h11a+
(C57BL/6NCrl-Zc3h11aem1(IMPC)Mbp/Mmucd)
abnormal thymus morphology J:211773
Zc3h12atm1Aki/Zc3h12atm1Aki
(involves: 129X1/SvJ * C57BL/6)
abnormal acute inflammation J:147868
abnormal class switch recombination J:147868
enlarged lymph nodes J:147868
enlarged spleen J:147868
granulomatous inflammation J:147868
increased anti-double stranded DNA antibody level J:147868
increased anti-nuclear antigen antibody level J:147868
increased IgA level J:147868
increased IgG1 level J:147868
increased IgG2a level J:147868
increased IgG2b level J:147868
increased IgG3 level J:147868
increased IgM level J:147868
increased immunoglobulin level J:147868
increased interferon-gamma secretion J:147868
increased interleukin-6 secretion J:147868
increased interleukin-12b secretion J:147868
increased leukocyte cell number J:147868
increased memory T cell number J:147868
increased plasma cell number J:147868
Zc3h12atm1c(EUCOMM)Hmgu/Zc3h12atm1c(EUCOMM)Hmgu
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6N)
increased inflammatory response J:304105
Zc3h12atm1c(EUCOMM)Hmgu/Zc3h12atm1c(EUCOMM)Hmgu
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+

(involves: C57BL/6 * C57BL/6N * DBA)
bile duct inflammation J:304105
enlarged spleen J:304105
granulomatous inflammation J:304105
increased anti-nuclear antigen antibody level J:304105
increased autoantibody level J:304105
increased IgG level J:304105
increased IgM level J:304105
liver inflammation J:304105
Zc3h12atm1Fum/Zc3h12atm1Fum
(C57BL/6-Zc3h12atm1Fum)
abnormal chemokine secretion J:176866
abnormal circulating chemokine level J:176866
enlarged lymph nodes J:176866
enlarged spleen J:176866
increased circulating tumor necrosis factor level J:176866
increased interleukin-1 beta secretion J:176866
increased interleukin-6 secretion J:176866
increased tumor necrosis factor secretion J:176866
Zc3h12bem1(IMPC)Tcp/Zc3h12bem1(IMPC)Tcp
(C57BL/6NCrl-Zc3h12bem1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Zc3h12cem1(IMPC)Tcp/Zc3h12cem1(IMPC)Tcp
(C57BL/6NCrl-Zc3h12cem1(IMPC)Tcp/Tcp)
decreased lymphocyte cell number J:211773
enlarged lymph nodes J:211773
increased neutrophil cell number J:211773
Zc3h12ctm2c(EUCOMM)Hmgu/Zc3h12ctm2c(EUCOMM)Hmgu
Cd19tm1(cre)Cgn/Cd19+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N)
immune system phenotype J:277714
Zc3h12ctm2c(EUCOMM)Hmgu/Zc3h12ctm2c(EUCOMM)Hmgu
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N)
enlarged lymph nodes J:277714
increased B cell number J:277714
increased CD4-positive, alpha-beta T cell number J:277714
increased effector memory CD8-positive, alpha-beta T cell number J:277714
increased immature B cell number J:277714
increased marginal zone B cell number J:277714
Zc3h12ctm2c(EUCOMM)Hmgu/Zc3h12ctm2c(EUCOMM)Hmgu
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJaeSor * C57BL/6N * DBA/2)
immune system phenotype J:277714
Zc3h12ctm2d(EUCOMM)Hmgu/Zc3h12ctm2d(EUCOMM)Hmgu
(involves: 129S4/SvJaeSor * C57BL/6N)
abnormal lymph node cortex morphology J:277714
abnormal lymph node primary follicle morphology J:277714
decreased CD8-positive, alpha-beta T cell number J:277714
decreased germinal center B cell number J:277714
decreased macrophage cell number J:277714
enlarged lymph nodes J:277714
immune system phenotype J:277714
increased B cell number J:277714
increased CD4-positive, alpha-beta T cell number J:277714
increased circulating interferon-gamma level J:277714
increased effector memory CD4-positive, alpha-beta T cell number J:277714
increased IgA level J:277714
increased IgG level J:277714
increased IgM level J:277714
increased immature B cell number J:277714
increased marginal zone B cell number J:277714
increased splenocyte number J:277714
increased T cell number J:277714
Zc3h12dtm1b(EUCOMM)Hmgu/Zc3h12dtm1b(EUCOMM)Hmgu
(C57BL/6N-Zc3h12dtm1b(EUCOMM)Hmgu/Orl)
decreased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
Zc3h12dtm1Tom/Zc3h12dtm1Tom
(B6.Cg-Zc3h12dtm1Tom)
immune system phenotype J:209383
increased interleukin-6 secretion J:209383
increased interleukin-10 secretion J:209383
increased susceptibility to experimental autoimmune encephalomyelitis J:209383
increased T cell proliferation J:209383
increased T-helper 17 cell number J:209383
Zc3hav1ltm1b(EUCOMM)Wtsi/Zc3hav1ltm1b(EUCOMM)Wtsi
(C57BL/6N-Zc3hav1ltm1b(EUCOMM)Wtsi/Tcp)
increased eosinophil cell number J:211773
Zcchc3em1Hbsh/Zcchc3em1Hbsh
(involves: C57BL/6)
abnormal innate immunity J:271802
decreased circulating CXCL10 level J:271802
decreased circulating interferon-beta level J:271802
decreased circulating interleukin-6 level J:271802
increased susceptibility to Herpesvirales infection J:271802
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:271802
increased susceptibility to Poxviridae infection induced morbidity/mortality J:271802
Zcchc17em1(IMPC)Hmgu/Zcchc17em1(IMPC)Hmgu
(C57BL/6NCrl-Zcchc17em1(IMPC)Hmgu/Ieg)
increased spleen weight J:211773
Zcwpw1em1(IMPC)Tcp/Zcwpw1em1(IMPC)Tcp
(C57BL/6N-Zcwpw1em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Zdbf2em1(IMPC)J/Zdbf2em1(IMPC)J
(C57BL/6NJ-Zdbf2em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Zdhhc1tm1Yyiw/Zdhhc1tm1Yyiw
(involves: 129S6/SvEvTac)
abnormal circulating cytokine level J:284987
decreased circulating interferon-alpha level J:284987
decreased circulating interferon-beta level J:284987
decreased circulating interleukin-6 level J:284987
decreased circulating tumor necrosis factor level J:284987
immune system phenotype J:284987
increased susceptibility to Herpesvirales infection J:284987
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:284987
Zdhhc2em1Eko/Zdhhc2em1Eko
(C57BL/6-Zdhhc2em1Eko)
abnormal cytokine level J:303593
abnormal interferon level J:303593
abnormal interleukin level J:303593
abnormal plasmacytoid dendritic cell physiology J:303593
abnormal T cell activation J:303593
abnormal tumor necrosis factor level J:303593
decreased dendritic epidermal T cell number J:303593
decreased leukocyte cell number J:303593
decreased plasmacytoid dendritic cell number J:303593
decreased susceptibility to chemically induced skin inflammation J:303593
increased alpha-beta T cell number J:303593
increased gamma-delta T cell number J:303593
Zdhhc9tm1Lex/Y
(involves: 129S5/SvEvBrd * C57BL/6)
abnormal leukocyte physiology J:231488
Zdhhc11tm1.1(KOMP)Vlcg/Zdhhc11tm1.1(KOMP)Vlcg
(involves: C57BL/6NTac)
decreased circulating interleukin-6 level J:310891
decreased susceptibility to endotoxin shock J:310891
decreased susceptibility to viral infection J:310891
Zdhhc13skc4/Zdhhc13skc4
(involves: 129S6/SvEvTac * C3H * C57BL/6)
abnormal Kupffer cell morphology J:161519
decreased leukocyte cell number J:161519
enlarged spleen J:161519
increased neutrophil cell number J:161519
Zeb1m1Btlr/Zeb1m1Btlr
(involves: C57BL/6J)
abnormal B cell differentiation J:185495
abnormal class switch recombination J:185495
abnormal memory B cell physiology J:185495
absent marginal zone B cells J:185495
decreased B cell proliferation J:185495
decreased B-1 B cell number J:185495
decreased B-1a cell number J:185495
decreased B-1b cell number J:185495
decreased double-positive T cell number J:185495
decreased germinal center B cell number J:185495
decreased IgG1 level J:185495
decreased IgG level J:185495
decreased IgM level J:185495
decreased NK cell number J:185495
immune system phenotype J:185495
increased single-positive T cell number J:185495
increased thymocyte number J:185495
Zeb1m2Btlr/Zeb1m2Btlr
(C57BL/6J-Zeb1m2Btlr)
impaired humoral immune response J:221490
Zeb1tm1Yhi/Zeb1tm1Yhi
(B6.129P2-Zeb1tm1Yhi)
abnormal T cell differentiation J:39865
abnormal T cell subpopulation ratio J:39865
abnormal thymus development J:39865
decreased CD8-positive, alpha-beta T cell number J:39865
decreased double-positive T cell number J:39865
decreased lymphocyte cell number J:39865
decreased splenocyte number J:39865
decreased T cell number J:39865
decreased thymocyte number J:39865
lymph node hypoplasia J:39865
small thymus J:39865
thymus hypoplasia J:39865
Zeb1tm2Yhi/Zeb1tm2Yhi
(B6.129-Zeb1tm2Yhi)
decreased thymocyte number J:45575
thymus hypoplasia J:45575
Zeb1Tw/Zeb1+
(B6.Cg-Zeb1Tw)
decreased leukocyte cell number J:177274
decreased lymphocyte cell number J:177274
decreased neutrophil cell number J:177274
small spleen J:177274
small thymus J:177274
Zfand2btm1Otin/Zfand2b+
(involves: 129S7/SvEvBrd * C57BL/6)
increased granulocyte number J:233169
Zfand2btm1Otin/Zfand2btm1Otin
(involves: 129S7/SvEvBrd * C57BL/6)
abnormal myeloid leukocyte morphology J:233169
decreased lymphocyte cell number J:233169
enlarged spleen J:233169
increased granulocyte number J:233169
increased leukocyte cell number J:233169
increased lymphocyte cell number J:233169
increased spleen weight J:233169
Zfand3em1(IMPC)J/Zfand3em1(IMPC)J
(C57BL/6NJ-Zfand3em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Zfand6em1(IMPC)Mbp/Zfand6em1(IMPC)Mbp
(C57BL/6N-Zfand6em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Zfatem1(IMPC)Ccpcz/Zfat+
(C57BL/6NCrl-Zfatem1(IMPC)Ccpcz/Ccpcz)
abnormal spleen morphology J:211773
abnormal thymus morphology J:211773
enlarged spleen J:211773
enlarged thymus J:211773
Zfattm2.1Sawa/Zfattm2.1Sawa
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * C57BL/6JJcl * C57BL/6NCrSlc * DBA/2)
abnormal CD4-positive, alpha-beta T cell physiology J:187164
abnormal CD8-positive, alpha-beta T cell differentiation J:187164
decreased CD4-positive, alpha-beta T cell number J:187164
decreased CD8-positive, alpha-beta T cell number J:187164
decreased interleukin-2 secretion J:187164
decreased T cell proliferation J:187164
immune system phenotype J:187164
increased T cell apoptosis J:187164
Zfp14tm1Xch/Zfp14+
(involves: C57BL/6)
chronic pancreas inflammation J:331393
increased inflammatory response J:331393
lymph node hyperplasia J:331393
spleen hyperplasia J:331393
thymus hyperplasia J:331393
Zfp14tm1Xch/Zfp14tm1Xch
(involves: C57BL/6)
chronic pancreas inflammation J:331393
increased inflammatory response J:331393
lymph node hyperplasia J:331393
spleen hyperplasia J:331393
thymus hyperplasia J:331393
Zfp30em1Snpk/Zfp30em1Snpk
(C57BL/6J-Zfp30em1Snpk/Mmnc)
immune system phenotype J:300801
Zfp35tm1Naka/Zfp35tm1Naka
(either: B6.Cg-Zfp35tm1Naka or C.Cg-Zfp35tm1Naka)
abnormal T-helper 2 cell differentiation J:153828
increased circulating interleukin-4 level J:153828
increased circulating interleukin-5 level J:153828
increased circulating interleukin-13 level J:153828
increased eosinophil cell number J:153828
Zfp36tm1(KOMP)Vlcg/Zfp36+
(C57BL/6N-Zfp36tm1(KOMP)Vlcg/Nju)
increased leukocyte cell number J:211773
Zfp36tm1Pjb/Zfp36tm1Pjb
(Not Specified)
abnormal thymus cortex morphology J:33986
abnormal thymus medulla morphology J:33986
arthritis J:33986
conjunctivitis J:33986
dermatitis J:33986
enlarged lymph nodes J:33986
enlarged spleen J:33986
heart inflammation J:33986
increased leukocyte cell number J:33986
liver inflammation J:33986
spleen hyperplasia J:33986
thymus hypoplasia J:33986
Zfp36tm1Pjb/Zfp36tm1Pjb
(B6.Cg-Zfp36tm1Pjb)
abnormal macrophage physiology J:88443
arthritis J:88443
blood vessel inflammation J:214114
decreased lymphocyte cell number J:214114
increased granulocyte number J:214114
increased monocyte cell number J:214114
increased neutrophil cell number J:214114
Zfp36tm2.1Pjb/Zfp36tm2.1Pjb
(involves: C57BL/6)
decreased inflammatory response J:229078
decreased susceptibility to experimental autoimmune encephalomyelitis J:229078
decreased susceptibility to induced arthritis J:229078
Zfp36tm4.1Pjb/Zfp36tm4.1Pjb
Lyz2tm1(cre)Ifo/Lyz2+

(involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N)
alveolitis J:188677
arthritis J:188677
enlarged lymph nodes J:188677
enlarged spleen J:188677
increased circulating tumor necrosis factor level J:188677
increased inflammatory response J:188677
increased spleen weight J:188677
increased susceptibility to endotoxin shock J:188677
Zfp36l1tm1.1Tnr/Zfp36l1tm1.1Tnr
Zfp36l2tm1.1Tnr/Zfp36l2tm1.1Tnr
Tg(CD2-icre)4Kio/0

(involves: C57BL/6 * C57BL/10 * CBA/Ca * SJL)
abnormal thymus development J:162388
enlarged lymph nodes J:162388
enlarged spleen J:162388
thymus atrophy J:162388
Zfp36l2tm2Pjb/Zfp36l2tm2Pjb
(involves: 129S7/SvEvBrd * C57BL/6)
decreased leukocyte cell number J:152911
decreased neutrophil cell number J:152911
decreased splenocyte number J:152911
Zfp91em1(IMPC)Tcp/Zfp91+
(C57BL/6N-Zfp91em1(IMPC)Tcp/Tcp)
enlarged lymph nodes J:211773
Zfp106tm1a(KOMP)Wtsi/Zfp106tm1a(KOMP)Wtsi
(involves: C57BL/6Brd * C57BL/6Dnk * C57BL/6N)
microgliosis J:229162
Zfp119atm1b(EUCOMM)Hmgu/Zfp119atm1b(EUCOMM)Hmgu
(C57BL/6N-Zfp119atm1b(EUCOMM)Hmgu/Ieg)
increased leukocyte cell number J:211773
Zfp131tm1.1Mytk/Zfp131tm1.1Mytk
Tg(Cd4-cre)1Cwi/0

(involves: C57BL/6 * C57BL/6N * DBA/2)
abnormal T cell subpopulation ratio J:271921
abnormal thymocyte activation J:271921
decreased CD4-positive, alpha-beta T cell number J:271921
decreased CD8-positive, alpha-beta T cell number J:271921
decreased T cell number J:271921
decreased T cell proliferation J:271921
immune system phenotype J:271921
Zfp131tm1.1Mytk/Zfp131tm1.2Mytk
Tg(Lck-cre)1Jtak/0

(involves: C57BL/6N * FVB/N)
abnormal double-negative T cell morphology J:271921
abnormal T cell differentiation J:271921
arrested T cell differentiation J:271921
decreased CD4-positive, alpha-beta T cell number J:271921
decreased CD8-positive, alpha-beta T cell number J:271921
decreased DN2 thymocyte number J:271921
decreased DN3 thymocyte number J:271921
decreased DN4 thymocyte number J:271921
decreased double-negative T cell number J:271921
decreased double-positive T cell number J:271921
decreased T cell proliferation J:271921
decreased thymocyte number J:271921
Zfp142tm1b(EUCOMM)Wtsi/Zfp142tm1b(EUCOMM)Wtsi
(C57BL/6N-Zfp142tm1b(EUCOMM)Wtsi/Bay)
abnormal spleen morphology J:211773
Zfp148tm1.1Jmer/Zfp148tm1.1Jmer
Tg(Vil1-cre)997Gum/0

(involves: C57BL/6 * C57BL/6J * SJL)
increased inflammatory response J:198847
increased susceptibility to bacterial infection J:198847
increased susceptibility to bacterial infection induced morbidity/mortality J:198847
Zfp148tm1Djl/Zfp148tm1Djl
(involves: 129)
increased susceptibility to induced colitis J:107441
Zfp160tm1b(EUCOMM)Wtsi/Zfp160tm1b(EUCOMM)Wtsi
(C57BL/6N-Zfp160tm1b(EUCOMM)Wtsi/BayMmucd)
decreased spleen weight J:211773
Zfp207tm1b(EUCOMM)Hmgu/Zfp207+
(C57BL/6N-Zfp207tm1b(EUCOMM)Hmgu/H)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Zfp236em1(IMPC)Mbp/Zfp236+
(C57BL/6NCrl-Zfp236em1(IMPC)Mbp/Mmucd)
abnormal spleen morphology J:211773
enlarged spleen J:211773
Zfp260tm1b(NCOM)Mfgc/Zfp260+
(C57BL/6N-Zfp260tm1b(NCOM)Mfgc/Tcp)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Zfp281em1(IMPC)Mbp/Zfp281+
(C57BL/6N-Zfp281em1(IMPC)Mbp/MbpMmucd)
abnormal spleen morphology J:211773
small spleen J:211773
Zfp292em1Zfa/Zfp292em1Zfa
(involves: C57BL/6)
increased susceptibility to bacterial infection J:259392
increased susceptibility to bacterial infection induced morbidity/mortality J:259392
Zfp318m1Anu/Zfp318+
(C57BL/6JAnu-Zfp318m1Anu)
decreased IgD level J:207375
increased IgM level J:207375
Zfp318m1Anu/Zfp318m1Anu
(C57BL/6JAnu-Zfp318m1Anu)
abnormal B cell number J:104190
abnormal follicular B cell physiology J:207375
abnormal marginal zone B cell physiology J:207375
decreased IgD level J:207375, J:104190
increased IgM level J:207375, J:104190
increased mature B cell number J:207375
Zfp318M1Btlr/Zfp318+
(C57BL/6J-Zfp318M1Btlr)
decreased IgD level J:218965
Zfp318M1Btlr/Zfp318M1Btlr
(C57BL/6J-Zfp318M1Btlr)
decreased IgD level J:218965
Zfp318tm1.1Jhws/Zfp318tm1.1Jhws
Commd10Tg(Vav1-icre)A2Kio/Commd10+

(B6.Cg-Zfp318tm1.1Jhws TgVav1-creA2Kio)
decreased IgD level J:215815
decreased transitional stage T2 B cell number J:215815
increased IgM level J:215815
Zfp318tm1Hhag/Zfp318tm1Hhag
(involves: 129 * C57BL/6)
decreased IgD level J:207375
increased IgM level J:207375
Zfp335blt/Zfp335blt
(involves: C57BL/6)
abnormal CD4-positive T cell differentiation J:214793
abnormal CD8-positive, alpha-beta T cell differentiation J:214793
abnormal T cell differentiation J:214793
decreased B cell number J:214793
decreased CD4-positive, alpha-beta memory T cell number J:214793
decreased CD4-positive, alpha-beta T cell number J:214793
decreased CD8-positive, alpha-beta memory T cell number J:214793
decreased CD8-positive, alpha-beta T cell number J:214793
decreased NK T cell number J:214793
decreased regulatory T cell number J:214793
decreased single-positive T cell number J:214793
Zfp354aem1(IMPC)Mbp/Zfp354aem1(IMPC)Mbp
(C57BL/6NCrl-Zfp354aem1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Zfp366b2b2834Clo/Zfp366b2b2834Clo
(C57BL/6J-Zfp366b2b2834Clo)
thymus hypoplasia J:175213
Zfp467tm1.1(KOMP)Vlcg/Zfp467tm1.1(KOMP)Vlcg
(B6(Cg)-Zfp467tm1.1(KOMP)Vlcg)
abnormal osteoclast physiology J:302865
increased osteoclast cell number J:302865
Zfp469em1(IMPC)Mbp/Zfp469em1(IMPC)Mbp
(C57BL/6N-Zfp469em1(IMPC)Mbp/MbpMmucd)
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
Zfp474em1(IMPC)Ccpcz/Zfp474em1(IMPC)Ccpcz
(C57BL/6N-Zfp474em1(IMPC)Ccpcz/Ccpcz)
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased neutrophil cell number J:211773
Zfp488em1(IMPC)Bay/Zfp488em1(IMPC)Bay
(C57BL/6N-Zfp488em1(IMPC)Bay/Bay)
abnormal spleen morphology J:211773
Zfp503em1(IMPC)Mbp/Zfp503+
(C57BL/6N-Zfp503em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
increased basophil cell number J:211773
Zfp513em1(IMPC)J/Zfp513em1(IMPC)J
(C57BL/6NJ-Zfp513em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Zfp521tm1Nohk/Zfp521tm1Nohk
(B6J.Cg-Zfp521tm1Nohk)
decreased spleen weight J:214267
decreased thymus weight J:214267
Zfp593em1(IMPC)J/Zfp593em1(IMPC)J
(C57BL/6NJ-Zfp593em1(IMPC)J/Mmjax)
decreased leukocyte cell number J:211773
Zfp595tm1b(KOMP)Wtsi/Zfp595tm1b(KOMP)Wtsi
(C57BL/6N-Zfp595tm1b(KOMP)Wtsi/Bay)
decreased eosinophil cell number J:211773
decreased leukocyte cell number J:211773
decreased lymphocyte cell number J:211773
Zfp616tm1b(KOMP)Wtsi/Zfp616tm1b(KOMP)Wtsi
(C57BL/6N-Zfp616tm1b(KOMP)Wtsi/Wtsi)
increased KLRG1-positive T-helper cell number J:211773
Zfp629em1(IMPC)Tcp/Zfp629em1(IMPC)Tcp
(C57BL/6N-Zfp629em1(IMPC)Tcp/Tcp)
small spleen J:211773
Zfp638em1(IMPC)J/Zfp638+
(C57BL/6NJ-Zfp638em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Zfp639tm1.2Jaty/Zfp639tm1.2Jaty
(involves: 129 * BALB/cJ * C57BL/6 * SJL)
decreased susceptibility to Retroviridae infection J:305874
immune system phenotype J:305874
Zfp644m1Anu/Zfp644m1Anu
(C57BL/6NCrlAnu-Zfp644m1Anu)
immune system phenotype J:104190
Zfp683Gt(OST314703)Lex/Zfp683Gt(OST314703)Lex
(B6.129S5-Zfp683Gt(OST314703)Lex)
abnormal NK T cell morphology J:187727
abnormal susceptibility to infection J:187727
decreased NK T cell number J:187727
immune system phenotype J:187727
increased interferon-gamma secretion J:187727
Zfp760tm1a(EUCOMM)Hmgu/Zfp760+
(C57BL/6N-Zfp760tm1a(EUCOMM)Hmgu/Ieg)
decreased IgE level J:165965
Zfp871tm1a(EUCOMM)Wtsi/Zfp871+
(C57BL/6N-Zfp871tm1a(EUCOMM)Wtsi/BayMmucd)
liver inflammation J:317166
spleen hyperplasia J:317166
thymus hyperplasia J:317166
Zfp950Gt(ROSA)76Sor/Zfp950Gt(ROSA)76Sor
(involves: 129S4/SvJaeSor)
kidney inflammation J:117491
Zfpm1tm1.1Esv/Zfpm1tm1.1Esv
(involves: 129S6/SvEvTac * C57BL/6)
abnormal spleen morphology J:156475
increased granulocyte number J:156475
increased neutrophil cell number J:156475
increased spleen red pulp amount J:156475
increased spleen weight J:156475
Zfpm1tm1.1Geab/Zfpm1tm1.1Geab
(Not Specified)
abnormal circulating chemokine level J:162629
decreased spleen white pulp amount J:156393
enlarged spleen J:156393
increased monocyte cell number J:156393
increased neutrophil cell number J:156393
increased spleen weight J:156393
spleen hypoplasia J:156393
Zftraf1em1(IMPC)H/Zftraf1em1(IMPC)H
(C57BL/6NTac-Zftraf1em1(IMPC)H/H)
decreased eosinophil cell number J:211773
Zfxtm1.1Reiz/Y
Tg(Mx1-cre)1Cgn/0

(involves: 129S6/SvEvTac * C57BL/6 * CBA)
decreased lymphocyte cell number J:149654
Zfxtm1.1Reiz/Y
Tg(Tek-cre)12Flv/0

(involves: 129S6/SvEvTac * C3H * C57BL/6)
decreased mature B cell number J:149654
decreased T cell number J:149654
Zfyve1em1Hbsh/Zfyve1em1Hbsh
(C57BL/6J-Zfyve1em1Hbsh)
decreased susceptibility to viral infection J:292942
decreased susceptibility to viral infection induced morbidity/mortality J:292942
Zfyve16tm2a(KOMP)Wtsi/Zfyve16tm2a(KOMP)Wtsi
(C57BL/6N-Zfyve16tm2a(KOMP)Wtsi)
decreased B cell number J:302014
decreased B cell proliferation J:302014
increased T cell number J:302014
Zg16tm1Lex/Zg16tm1Lex
(B6.129S-Zg16tm1Lex)
increased circulating interferon-gamma level J:239095
increased circulating interleukin-6 level J:239095
increased susceptibility to bacterial infection J:239095
Zic2iso/Zic2iso
(involves: C3H/HeH * C57BL/6)
abnormal spleen morphology J:268103
abnormal spleen size J:268103
absent spleen J:268103
Zic3tm1Bca/Y
(involves: 129S7/SvEvBrd * C57BL/6)
spleen hypoplasia J:75951
Zic3tm1Bca/Zic3+
(involves: 129S7/SvEvBrd * C57BL/6)
spleen hypoplasia J:75951
Zic3tm1Bca/Zic3tm1Bca
(involves: 129S7/SvEvBrd * C57BL/6)
spleen hypoplasia J:75951
Zkscan3tm1.2Itl/Zkscan3tm1.2Itl
(B6.Cg-Zkscan3tm1.2Itl)
abnormal response to infection J:318724
Zkscan7em1(IMPC)Mbp/Zkscan7em1(IMPC)Mbp
(C57BL/6N-Zkscan7em1(IMPC)Mbp/MbpMmucd)
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
Zmpste24tm1Otin/Zmpste24tm1Otin
(involves: 129P2/Ola * C57BL/6)
abnormal thymus corticomedullary boundary morphology J:76209
thymus hypoplasia J:76209
Zmym2em1(IMPC)J/Zmym2+
(C57BL/6NJ-Zmym2em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Zmynd10tm1(KOMP)Wtsi/Zmynd10tm1(KOMP)Wtsi
(involves: C57BL/6J * C57BL/6N)
lung inflammation J:261915
Zmynd11em1(IMPC)Wtsi/Zmynd11em1(IMPC)Wtsi
(C57BL/6N-Zmynd11em1(IMPC)Wtsi/WtsiIeg)
blood in lymph vessels J:239583
Znhit2em1(IMPC)J/Znhit2+
(C57BL/6NJ-Znhit2em1(IMPC)J/Mmjax)
increased leukocyte cell number J:211773
Znhit6em1(IMPC)Mbp/Znhit6+
(C57BL/6N-Znhit6em1(IMPC)Mbp/Ucd)
abnormal lymph node morphology J:211773
enlarged lymph nodes J:211773
Zranb1em1Shios/Zranb1em1Shios
(involves: C57BL/6)
increased susceptibility to colitis induced morbidity/mortality J:333468
Zranb1tm1c(EUCOMM)Hmgu/Zranb1tm1c(EUCOMM)Hmgu
Tg(Cd4-cre)1Cwi/0

(involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * DBA/2)
immune system phenotype J:235701
Zranb1tm1c(EUCOMM)Hmgu/Zranb1tm1c(EUCOMM)Hmgu
Tg(Itgax-cre)1-1Reiz/0

(involves: 129S4/SvJaeSor * C57BL/6N * CBA)
abnormal dendritic cell physiology J:235701
decreased susceptibility to experimental autoimmune encephalomyelitis J:235701
decreased T helper 1 cell number J:235701
decreased T-helper 17 cell number J:235701
immune system phenotype J:235701
Zranb1tm1d(EUCOMM)Hmgu/Zranb1tm1d(EUCOMM)Hmgu
(involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6N)
decreased CD4-positive, alpha-beta T cell number J:235701
decreased circulating interferon-gamma level J:235701
decreased circulating interleukin-17 level J:235701
decreased susceptibility to experimental autoimmune encephalomyelitis J:235701
decreased T helper 1 cell number J:235701
decreased T-helper 17 cell number J:235701
immune system phenotype J:235701
Zrsr2em1(IMPC)Mbp/Y
(C57BL/6N-Zrsr2em1(IMPC)Mbp/MbpMmucd)
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
Zscan10Gt(285B6)1.1Cmhd/Zscan10Gt(285B6)1.1Cmhd
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N)
abnormal IgG level J:221010
abnormal T cell subpopulation ratio J:221010
decreased spleen weight J:221010
decreased T cell number J:221010
increased B cell number J:221010
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:221010
increased IgG1 level J:221010
increased IgG2b level J:221010
increased mature NK cell number J:221010
Zswim1tm1b(KOMP)Mbp/Zswim1tm1b(KOMP)Mbp
(C57BL/6N-Zswim1tm1b(KOMP)Mbp/Nju)
decreased lymphocyte cell number J:211773
decreased monocyte cell number J:211773
increased basophil cell number J:211773
increased eosinophil cell number J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory