Atm^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atm^m2Btlr
• Name: ataxia telangiectasia mutated; mutation 2, Bruce Beutler
• MGI ID: MGI:6200335
• Synonyms: mockingbird2
• Gene: Atm Location: Chr9:53350449-53448040 bp, - strand Genetic Position: Chr9, 29.12 cM, cytoband C-D
• Alliance: Atm^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 53,488,587 (v38) on chromosome 9, or base pair 48,230 in the GenBank genomic region NC_000075. The mutation corresponds to residue 4,731 in the mRNA sequence NM_007499 within exon 29 of 64 total exons. The mutation results in a leucine to proline substitution at amino acid 1,531 (L1531P) in the ATM protein. (J:265253)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atm Mutation: 169 strains or lines available

References

• Original: J:265253 Zhong X, et al., Mutagenetix entry for mockingbird2. MGI Direct Data Submission. 2018
• All: 1 reference(s)