Tg(Lck-Cxadr)1Jdgr
Transgene Detail

Summary

• Symbol: Tg(Lck-Cxadr)1Jdgr
• Name: transgene insertion 1, James DeGregori
• MGI ID: MGI:3686860
• Synonyms: CARdelta1 Tg, CAR Tg
• Transgene: Tg(Lck-Cxadr)1Jdgr Location: unknown
• Alliance: Tg(Lck-Cxadr)1Jdgr page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-Cxadr)1Jdgr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cxadr (MGI:1201679)

• Mutation details: A cDNA encoding the coxsackie/adenovirus receptor (CAR) protein, but lacking the cytoplasmic domain was cloned into a construct containing the LckB proximal promoter/human CD2 enhancer. (J:109884)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:109884 Wan YY, et al., Transgenic expression of the coxsackie/adenovirus receptor enables adenoviral-mediated gene delivery in naive T cells. Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13784-9
• All: 15 reference(s)