Cd79a^tm3Cgn
Targeted Allele Detail

Summary

• Symbol: Cd79a^tm3Cgn
• Name: CD79A antigen (immunoglobulin-associated alpha); targeted mutation 3, University of Cologne
• MGI ID: MGI:3038712
• Synonyms: Igalpha^Tmf/deltaTm
• Gene: Cd79a Location: Chr7:24596922-24601283 bp, + strand Genetic Position: Chr7, 13.49 cM
• Alliance: Cd79a^tm3Cgn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:88620
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 and 3, which encode the extracellular and transmembrane domains, were flanked by loxP sites. (J:88620)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd79a Mutation: 22 strains or lines available

References

• Original: J:88620 Nolte MA, et al., B cells are crucial for both development and maintenance of the splenic marginal zone. J Immunol. 2004 Mar 15;172(6):3620-7
• All: 1 reference(s)