About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd79atm3Cgn
targeted mutation 3, University of Cologne
MGI:3038712
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Cd79atm3Cgn/Cd79atm4.1Cgn involves: C57BL/6 * CBA MGI:3716169
cn2
 		Cd79atm3Cgn/Cd79atm3Cgn
Tg(Mx1-cre)1Cgn/? 		involves: C57BL/6 * CBA MGI:3716167


Genotype
MGI:3716169
ht1
Allelic
Composition		 Cd79atm3Cgn/Cd79atm4.1Cgn
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79atm3Cgn mutation (0 available); any Cd79a mutation (22 available)
Cd79atm4.1Cgn mutation (1 available); any Cd79a mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:88620 )
N
• following treatment with poly(I)/poly(C), B cell numbers are normal




Genotype
MGI:3716167
cn2
Allelic
Composition		 Cd79atm3Cgn/Cd79atm3Cgn
Tg(Mx1-cre)1Cgn/?
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79atm3Cgn mutation (0 available); any Cd79a mutation (22 available)
Tg(Mx1-cre)1Cgn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:88620 )
• following treatment with poly(I)/poly(C), B cell numbers are decreased by up to 70% of wild-type numbers in the red pulp of the spleen
abnormal metallophilic macrophage morphology ( J:88620 )
• following treatment with poly(I)/poly(C), marginal metallophilic macrophages are decreased in number in areas where B cell numbers are reduced
abnormal spleen marginal zone macrophage morphology ( J:88620 )
• following treatment with poly(I)/poly(C), marginal zone metallophilic macrophages are decreased in number in areas where B cell numbers are reduced
abnormal spleen red pulp morphology ( J:88620 )
• following treatment with poly(I)/poly(C), B cell numbers are decreased by up to 70% of wild-type numbers in the red pulp of the spleen
• following treatment with poly(I)/poly(C), follicles are reduced in size

immune system
decreased B cell number ( J:88620 )
• following treatment with poly(I)/poly(C), B cell numbers are decreased by up to 70% of wild-type numbers in the red pulp of the spleen
abnormal metallophilic macrophage morphology ( J:88620 )
• following treatment with poly(I)/poly(C), marginal metallophilic macrophages are decreased in number in areas where B cell numbers are reduced
abnormal spleen marginal zone macrophage morphology ( J:88620 )
• following treatment with poly(I)/poly(C), marginal zone metallophilic macrophages are decreased in number in areas where B cell numbers are reduced
abnormal spleen red pulp morphology ( J:88620 )
• following treatment with poly(I)/poly(C), B cell numbers are decreased by up to 70% of wild-type numbers in the red pulp of the spleen
• following treatment with poly(I)/poly(C), follicles are reduced in size




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory