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Tg(Mx1-cre)1Cgn
Transgene Detail
Summary
Symbol: Tg(Mx1-cre)1Cgn
Name: transgene insertion 1, University of Cologne
MGI ID: MGI:2176073
Synonyms: Mx1cre, Mx1-Cre, MxCre, Mx-Cre, Mx-Cre 31, MxCreTg, Tg(Mx1-cre)hemi
Transgene: Tg(Mx1-cre)1Cgn  Location: unknown  Genetic Position: Chr10, Syntenic
Alliance: Tg(Mx1-cre)1Cgn page
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA/J)F2
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    interferon or polyinosinic-polycytidylic acid
Mutation:    Insertion
 
Tg(Mx1-cre)1Cgn expression driven by 1 gene
 
Mutation detailsThis transgene expresses Cre recombinase under the control of an inducible Mx1 promoter, which is silent in healthy mice, and active in the liver and in lymphocytes after induction with IFN or pI-pC. The construct also contains a 2.1 kb fragment from the human growth hormone gene. (J:67927)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mx1 (species not specified)
Summary of all recombinase alleles driven by Mx1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Tumor Data
List all tumor models in MMHCdb carrying Tg(Mx1-cre)1Cgn
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 7 strains available      Cell Lines: 0 lines available
References
Original:  J:67927 Kuhn R, et al., Inducible gene targeting in mice. Science. 1995 Sep 8;269(5229):1427-9
All:  1310 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory