Del(7Pira1-Lilra6)1Fgla
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(7Pira1-Lilra6)1Fgla
• Name: deletion, Chr 7, Fadi G Lakkis 1
• MGI ID: MGI:6694109
• Synonyms: Pira^-
• Gene: Del(7Pira1-Lilra6)1Fgla Location: unknown Genetic Position: Chr7, Syntenic

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Mutation details: The cluster, comprising Pira1, Pira2-ps1, Pira13, Pira2, Pira12 and Lilra6, was deleted using two sgRNAs (in a Pira1 intron and downstream of Lilra6) with CRISPR/Cas9 technology. (J:290663)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(7Pira1-Lilra6)1Fgla Mutation: 0 strains or lines available

References

• Original: J:290663 Dai H, et al., PIRs mediate innate myeloid cell memory to nonself MHC molecules. Science. 2020 Jun 5;368(6495):1122-1127
• All: 1 reference(s)