About   Help   FAQ
Foxp3tm1Kuch
Targeted Allele Detail
Summary
Symbol: Foxp3tm1Kuch
Name: forkhead box P3; targeted mutation 1, Vijay K Kuchroo
MGI ID: MGI:3718527
Synonyms: Fox3eGFP, Foxp3eGFP, Foxp3-eGFP, Foxp3-GFP, Foxp3/GFP+, Foxp3gfp.KI, Foxp3-GFP.KI, Foxp3-IRES-GFP
Gene: Foxp3  Location: ChrX:7445915-7461482 bp, + strand  Genetic Position: ChrX, 3.41 cM
Alliance: Foxp3tm1Kuch page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123469
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsA bicistronic enhanced green fluorescent protein reporter (IRES-GFP) was inserted into the locus. EGFP can be used to faithfully track the expression of the endogenous gene. No disruption to Foxp3 gene function or expression is observed. (J:123469)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxp3 Mutation:  55 strains or lines available
References
Original:  J:123469 Bettelli E, et al., Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006 May 11;441(7090):235-8
All:  179 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory