Myd88^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Myd88^m3Btlr
• Name: myeloid differentiation primary response gene 88; mutation 3, Bruce Beutler
• MGI ID: MGI:4422086
• Synonyms: Myd88rev1
• Gene: Myd88 Location: Chr9:119165000-119169084 bp, - strand Genetic Position: Chr9, 71.33 cM
• Alliance: Myd88^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, identified in a gene-specific sequence screen of G1 progeny of ENU mutagenized male mice, comprises a T to A transversion at position 934 of the transcript, in the fifth of six exons. It results in replacement of a highly conserved phenylalanine at amino acid position 285 by isoleucine (F285I). (J:156848)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myd88 Mutation: 50 strains or lines available

References

• Original: J:156848 Khovananth K, et al., Altering a highly conserved residue in the MyD88 TIR domain using ENU results in normal function. MGI Direct Data Submission. 2010
• All: 2 reference(s)