Id3^tm2.1Zhu
Targeted Allele Detail

Summary

• Symbol: Id3^tm2.1Zhu
• Name: inhibitor of DNA binding 3; targeted mutation 2.1, Yuan Zhuang
• MGI ID: MGI:5009711
• Synonyms: Id3^f, Id3^L
• Gene: Id3 Location: Chr4:135871133-135872703 bp, + strand Genetic Position: Chr4, 68.34 cM
• Alliance: Id3^tm2.1Zhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172701
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exons 1 and 2 floxed. (J:172701)

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Id3 Mutation: 16 strains or lines available

References

• Original: J:172701 Guo Z, et al., Modeling Sjogren's syndrome with Id3 conditional knockout mice. Immunol Lett. 2011 Mar 30;135(1-2):34-42
• All: 23 reference(s)