Snrpb^em1Lajm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Snrpb^em1Lajm
• Name: small nuclear ribonucleoprotein B; endonuclease-mediated mutation 1, Loydie Anne Jerome-Majewska
• MGI ID: MGI:7437928
• Synonyms: Snrpb^loxP
• Gene: Snrpb Location: Chr2:130013555-130021323 bp, - strand Genetic Position: Chr2, 63.19 cM
• Alliance: Snrpb^em1Lajm page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Two rounds of CRISPR-cas9 mediated recombination inserted loxP sites in introns 1 and 3 to flox exons 2 and 3. (J:326544)

Disease models

Expression

In Structures Affected by this Mutation:

53 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snrpb Mutation: 16 strains or lines available

References

• Original: J:326544 Alam SS, et al., Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis. Dis Model Mech. 2022 Jun 1;15(6):dmm049544
• All: 1 reference(s)