Lyst^bg
Radiation induced Allele Detail

Summary

• Symbol: Lyst^bg
• Name: lysosomal trafficking regulator; beige
• MGI ID: MGI:1855968
• Synonyms: 30B/22B, bg, CHS mice
• Gene: Lyst Location: Chr13:13764982-13953388 bp, + strand Genetic Position: Chr13, 5.28 cM
• Alliance: Lyst^bg page

Mutation origin

• Strain of Origin: C3H/Rl

Mutation description

• Allele Type: Radiation induced
• Mutation: Transposon insertion
• Mutation details: This allele is an insertion of a partial LINE 1 repetitive element into an intron of the gene. The insertion included only the most 3' 1097 bp of the element producing a frameshift mutation resulting in a truncated protein predicted to be missing the last 1442 amino acids. (J:33734, J:41243)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	6 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Lyst^bg

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any Lyst Mutation: 225 strains or lines available

References

• Original: J:29744 Kelly EM, Beige, bg. Mouse News Lett. 1957;16:36
• All: 130 reference(s)