Bnip3l^{Gt(XT0573)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Bnip3l^{Gt(XT0573)Wtsi}
• Name: BCL2/adenovirus E1B interacting protein 3-like; gene trap XT0573, Wellcome Trust Sanger Institute
• MGI ID: MGI:3802624
• Synonyms: Nix^-
• Gene: Bnip3l Location: Chr14:67222688-67246326 bp, - strand Genetic Position: Chr14, 34.6 cM
• Alliance: Bnip3l^{Gt(XT0573)Wtsi} page

Mutation origin

• Mutant Cell Line: XT0573
• Germline Transmission: Earliest citation of germline transmission: J:137609
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxf
• Mutation details: A gene trap vector containing the beta-geo cassette was inserted into intron 3. The absence of endogenous transcript was confirmed by RT-PCR analysis on kidney extracts. (J:137609)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XT0573	CG870123 ; (MGI Seq Detail)	5' RACE	Chr14:67231325-67246324 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  13 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bnip3l Mutation: 40 strains or lines available

References

• Original: J:137609 Sandoval H, et al., Essential role for Nix in autophagic maturation of erythroid cells. Nature. 2008 Jul 10;454(7201):232-5
• All: 1 reference(s)