Apol7c^em4Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Apol7c^em4Gpt
• Name: apolipoprotein L 7c; endonuclease-mediated mutation 4, GemPharmatech
• MGI ID: MGI:8205014
• Synonyms: Apol7c^em4Cd5691
• Gene: Apol7c Location: Chr15:77409052-77417516 bp, - strand Genetic Position: Chr15, 36.4 cM
• Alliance: Apol7c^em4Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 4 and 5. (J:362930)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apol7c Mutation: 22 strains or lines available

References

• Original: J:362930 Gonzales GA, et al., The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by dendritic cells. Sci Immunol. 2024 Nov;9(101):eadn2168
• All: 1 reference(s)