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Apol7cem4Gpt
Endonuclease-mediated Allele Detail
Summary
Symbol: Apol7cem4Gpt
Name: apolipoprotein L 7c; endonuclease-mediated mutation 4, GemPharmatech
MGI ID: MGI:8205014
Synonyms: Apol7cem4Cd5691
Gene: Apol7c  Location: Chr15:77409052-77417516 bp, - strand  Genetic Position: Chr15, 36.4 cM
Alliance: Apol7cem4Gpt page
Mutation
origin
Strain of Origin:  C57BL/6JGpt
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/Cas9 technology deleted exons 4 and 5. (J:362930)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Apol7c Mutation:  22 strains or lines available
References
Original:  J:362930 Gonzales GA, et al., The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by dendritic cells. Sci Immunol. 2024 Nov;9(101):eadn2168
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory