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Ebf1M3Btlr
Chemically induced Allele Detail
Summary
Symbol: Ebf1M3Btlr
Name: early B cell factor 1; mutation 3, Bruce Beutler
MGI ID: MGI:6199994
Synonyms: Oregano2
Gene: Ebf1  Location: Chr11:44508144-44898918 bp, + strand  Genetic Position: Chr11, 26.45 cM
Alliance: Ebf1M3Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced T to A transversion at base pair 44,990,504 (v38) on chromosome 11, or base pair 372,405 in the GenBank genomic region NC_000077 within intron 11 (12 base pairs from exon 12. The effect of the mutation at the cDNA and protein levels has not been examined, but the mutation is predicted to result in the use of a cryptic site in intron 11, resulting in a 31-base pair insertion of intron 11. The insertion would cause a frame-shifted protein product beginning after amino acid 376 of the protein and premature termination after the inclusion of 14 aberrant amino acids. (J:265160)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf1 Mutation:  73 strains or lines available
References
Original:  J:265160 Choi JH, et al., Mutagenetix entry for Oregano2. MGI Direct Data Submission. 2018;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory