Rbm43^em1Brsp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rbm43^em1Brsp
• Name: RNA binding motif protein 43; endonuclease-mediated mutation 1, Bruce M Spiegelman
• MGI ID: MGI:8161451
• Synonyms: Rbm43^fl
• Gene: Rbm43 Location: Chr2:51814460-51825175 bp, - strand Genetic Position: Chr2, 29.98 cM, cytoband C1
• Alliance: Rbm43^em1Brsp page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 genome editing technology was used to insert loxP sites surrounding exon 3. (J:363192)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm43 Mutation: 19 strains or lines available

References

• Original: J:363192 Dumesic PA, et al., RBM43 controls PGC1alpha translation and a PGC1alpha-STING signaling axis. Cell Metab. 2025 Mar 4;37(3):742-757.e8
• All: 1 reference(s)