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Rbm43 Gene Detail
Summary
  • Symbol
    Rbm43
  • Name
    RNA binding motif protein 43
  • Synonyms
    0610033I05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918934
    NCBI Gene: 71684
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:51814460-51825175 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 29.98 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    374 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918934
 protein coding gene Chr2:51814460-51825175 (-)
129S1/SvImJ ENSMUSG00200010414
 protein coding gene Chr2:48791096-48801750 (-)
A/J ENSMUSG00195009730
 protein coding gene Chr2:48940131-48950788 (-)
AKR/J ENSMUSG00220019771
 protein coding gene Chr2:49073121-49083777 (-)
BALB/cJ ENSMUSG00180020235
 protein coding gene Chr2:48933812-48944528 (-)
C3H/HeJ ENSMUSG00175013192
 protein coding gene Chr2:48964353-48975007 (-)
C57BL/6NJ ENSMUSG00215009879
 protein coding gene Chr2:48979593-48990306 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023552
 protein coding gene Chr2:47243435-47254172 (-)
CAST/EiJ ENSTCUG00005001395
 protein coding gene Chr2:48482754-48493435 (-)
CBA/J ENSMUSG00210000547
 protein coding gene Chr2:48977553-48988207 (-)
DBA/2J ENSMUSG00185002573
 protein coding gene Chr2:48845025-48855680 (-)
FVB/NJ ENSMUSG00205001677
 protein coding gene Chr2:48649078-48659759 (-)
JF1/MsJ ENSUMUG00000000429
 protein coding gene Chr2:48673014-48683706 (-)
LP/J ENSMUSG00230000541
 protein coding gene Chr2:50758434-50769144 (-)
NOD/ShiLtJ ENSMUSG00190001984
 protein coding gene Chr2:48892727-48903381 (-)
NZO/HlLtJ ENSMUSG00225000259
 protein coding gene Chr2:58469554-58480259 (-)
PWK/PhJ ENSLUMG00010004131
 protein coding gene Chr2:48829877-48840553 (-)
SPRET/EiJ ENSMSPG00010010552
 protein coding gene Chr2:49818434-49829204 (-)
WSB/EiJ ENSIUOG00005001179
 protein coding gene Chr2:48930663-48941319 (-)



Homology
more
  • Human Ortholog
    RBM43, RNA binding motif protein 43
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBM43, RNA binding motif protein 43
  • Synonyms
    C2orf38
  • Links
    NCBI Gene ID: 375287
    UniProt: Q6ZSC3

  • Chr Location
    2q23.3; chr2:151247940-151261863 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    619
  • Tissues
    22
  • cDNA Data
    39
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71684 NCBI Gene Model | MGI Sequence Detail 10716 C57BL/6J ±  kb
    transcript NM_001141981 RefSeq | MGI Sequence Detail 2213 C57BL/6  
    polypeptide Q99J64 UniProt | EBI | MGI Sequence Detail 343 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      cDNA 39
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:62678 Phillips RL, et al., The genetic program of hematopoietic stem cells. Science. 2000 Jun 2;288(5471):1635-40
    • Latest
      J:363192 Dumesic PA, et al., RBM43 controls PGC1alpha translation and a PGC1alpha-STING signaling axis. Cell Metab. 2025 Mar 4;37(3):742-757.e8
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory