Tg(H2-K-DUSP5)21Wjl
Transgene Detail
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Symbol: |
Tg(H2-K-DUSP5)21Wjl |
Name: |
transgene insertion 21, Warren J Leonard |
MGI ID: |
MGI:3807515 |
Synonyms: |
Tg(H2-K-DUSP5)1Wjl |
Transgene: |
Tg(H2-K-DUSP5)21Wjl Location: unknown
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Alliance: |
Tg(H2-K-DUSP5)21Wjl page
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Ulcerative dermatitis and kidney glomerular lesions in Tg(H2-K-DUSP5)21Wjl/0 mice
Show the 1 phenotype image(s) involving this allele.
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(H2-K-DUSP5)21Wjl expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
DUSP5 (1847) |
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Mutation details: A human DUSP5 cDNA with a C-terminal c-Myc epitope tag was cloned between the H2-Kb promoter and beta-blobin exons 2 and 3, a polyadenylation signal and an immunoglobin heavy chain enhancer. Protein expression was confirmed by western blotting. Two founder lines were produced. Data from only one representative line was reported.
(J:138077)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:138077 Kovanen PE, et al., T-cell development and function are modulated by dual specificity phosphatase DUSP5. J Biol Chem. 2008 Jun 20;283(25):17362-9 |
All: |
1 reference(s) |
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