Ppic^em1Igc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppic^em1Igc
• Name: peptidylprolyl isomerase C; endonuclease-mediated mutation 1, Instituto Gulbenkian de Ciencia
• MGI ID: MGI:6886012
• Gene: Ppic Location: Chr18:53539413-53551079 bp, - strand Genetic Position: Chr18, 29.03 cM, cytoband D1
• Alliance: Ppic^em1Igc page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting of exon 1 inserted 4 bp producing a frameshift mutation and truncated protein. (J:321155)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppic Mutation: 15 strains or lines available

References

• Original: J:321155 Paiva RS, et al., Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice. Eur J Immunol. 2021 Aug;51(8):1968-1979
• All: 1 reference(s)