About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppicem1Igc
endonuclease-mediated mutation 1, Instituto Gulbenkian de Ciencia
MGI:6886012
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ppicem1Igc/Ppicem1Igc C57BL/6-Ppicem1Igc MGI:6886063


Genotype
MGI:6886063
hm1
Allelic
Composition		 Ppicem1Igc/Ppicem1Igc
Genetic
Background		 C57BL/6-Ppicem1Igc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppicem1Igc mutation (0 available); any Ppic mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased NK cell number ( J:321155 )
• reduced invariant NK T cells with reduced later stage differentiation S2 and S3 cells
• however, early stage S0 and S1 cell numbers are normal

hematopoietic system
hematopoietic system phenotype ( J:321155 )
N
• mice exhibit normal hematopoietic progenitors in the bone marrow and alpha-beta or gamma-delta T lymphocyte differentiation
decreased NK cell number ( J:321155 )
• reduced invariant NK T cells with reduced later stage differentiation S2 and S3 cells
• however, early stage S0 and S1 cell numbers are normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory