Rgs13tm1.1Jhk
Targeted Allele Detail
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Symbol: |
Rgs13tm1.1Jhk |
Name: |
regulator of G-protein signaling 13; targeted mutation 1.1, John H Kehrl |
MGI ID: |
MGI:5514157 |
Gene: |
Rgs13 Location: Chr1:144014392-144053110 bp, - strand Genetic Position: Chr1, 62.56 cM
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Alliance: |
Rgs13tm1.1Jhk page
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Large germinal centers in Rgs13tm1.1Jhk/Rgs13tm1.1Jhk mice
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:199530
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The coding region contained without exon 3 was replaced with EGFP and floxed neomycin resistance cassette. Cre-mediated recombination removed the neomycin resistance cassette. RT-PCR confirmed the absence of transcript expression in splenic B cells or Peyer's Patch B.
(J:199530)
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Construction of the Rgs13tm1.1Jhk allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rgs13 Mutation: |
15 strains or lines available
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Original: |
J:199530 Hwang IY, et al., Rgs13 constrains early B cell responses and limits germinal center sizes. PLoS One. 2013;8(3):e60139 |
All: |
1 reference(s) |
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