Nbeal2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Nbeal2^tm1Lex
• Name: neurobeachin-like 2; targeted mutation 1, Lexicon Pharmaceuticals
• MGI ID: MGI:5007262
• Gene: Nbeal2 Location: Chr9:110453857-110483229 bp, - strand Genetic Position: Chr9, 60.27 cM
• Alliance: Nbeal2^tm1Lex page

Impaired wound healing in Nbeal2^tm1Lex/Nbeal2^tm1Lex mice

Show the 6 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 4 through 11 of the coding region were targeted by homologous recombination. RT-PCR confirmed absence of mRNA in different tissues. (J:171883, J:201413)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nbeal2 Mutation: 98 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 14 reference(s)