Tti2^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Tti2^{tm1b(KOMP)Wtsi}
• Name: TELO2 interacting protein 2; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5699602
• Gene: Tti2 Location: Chr8:31640344-31654731 bp, + strand Genetic Position: Chr8, 18.03 cM
• Alliance: Tti2^{tm1b(KOMP)Wtsi} page
• IMPC: Tti2 gene page

Mutation origin

• Mutant Cell Line: EPD0852_4_D05
• Germline Transmission: Earliest citation of germline transmission: J:204739
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre-mediated excision of the parental Tti2^{tm1a(KOMP)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette and exon, 2 leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tti2 Mutation: 20 strains or lines available

References

• Original: J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023
• All: 3 reference(s)