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Spontaneous Allele Detail
Symbol: Hrhr
Name: lysine demethylase and nuclear receptor corepressor; hairless
MGI ID: MGI:1856057
Synonyms: hr, SKH-1
Gene: Hr  Location: Chr14:70789652-70810988 bp, + strand  Genetic Position: Chr14, 36.32 cM
Alliance: Hrhr page
Hrhr/Hrhr mouse

Show the 3 phenotype image(s) involving this allele.

Strain of Origin:  Not Specified
Allele Type:    Spontaneous
Mutation:    Viral insertion
Mutation detailsThe hr allele is the result of a retroviral integration. Insertion of murine leukemia proviral sequences into intron 6 results in aberrant splicing of the gene. (J:9252, J:19624, J:92053)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 11 anatomical structures
Tumor Data
List all tumor models in MMHCdb carrying Hrhr
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 17 strains available      Cell Lines: 0 lines available
Carrying any Hr Mutation:  64 strains or lines available
Original:  J:2405 Brooke HC, Hairless mice. J Hered. 1926;17(5):173-74
All:  123 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory