Gpr146^em1Bdu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr146^em1Bdu
• Name: G protein-coupled receptor 146; endonuclease-mediated mutation 1, Bing Du
• MGI ID: MGI:6368525
• Gene: Gpr146 Location: Chr5:139363452-139382170 bp, + strand Genetic Position: Chr5, 78.49 cM, cytoband G1
• Alliance: Gpr146^em1Bdu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting with 5'-TGCCGGAACCTGCGCCTG-3' deleted 148 bp. (J:247263)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr146 Mutation: 19 strains or lines available

References

• Original: J:247263 Huang H, et al., Elimination of GPR146-mediated antiviral function through IRF3/HES1-signalling pathway. Immunology. 2017 Sep;152(1):102-114
• All: 1 reference(s)