About   Help   FAQ
Ebf1M5Btlr
Chemically induced Allele Detail
Summary
Symbol: Ebf1M5Btlr
Name: early B cell factor 1; mutation 5, Bruce Beutler
MGI ID: MGI:6286040
Synonyms: Befuddled
Gene: Ebf1  Location: Chr11:44508144-44898918 bp, + strand  Genetic Position: Chr11, 26.45 cM
Alliance: Ebf1M5Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced A to G transition at base pair 44,632,775 (v38) on chromosome 11, or base pair 14,676 in the GenBank genomic region NC_000077. The mutation corresponds to residue 515 in the mRNA sequence NM_001290709 within exon 5 of 16 total exons. The mutation results in a lysine to glutamic acid substitution at position 146 (K146E) in the EBF1 protein. (J:272841)
Inheritance:    Other (see notes)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf1 Mutation:  73 strains or lines available
Notes
Inheritance is unknown/not applicable. https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3739
References
Original:  J:272841 Zhong X, et al., Mutagenetix entry for Befuddled. MGI Direct Data Submission. 2019;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/28/2024
MGI 6.13
The Jackson Laboratory