Wls^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Wls^tm1.1Arte
• Name: wntless WNT ligand secretion mediator; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5547720
• Synonyms: Evi^fl, Evi^floxed
• Gene: Wls Location: Chr3:159545309-159644300 bp, + strand Genetic Position: Chr3, 82.65 cM
• Alliance: Wls^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202499
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A puromycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the puromycin resistance cassette and left exon 3 floxed. (J:202499)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wls Mutation: 38 strains or lines available

References

• Original: J:202499 Augustin I, et al., Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis. J Exp Med. 2013 Aug 26;210(9):1761-77
• All: 5 reference(s)