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Il4tm1Nnt
Targeted Allele Detail
Summary
Symbol: Il4tm1Nnt
Name: interleukin 4; targeted mutation 1, Nancy Noben-Trauth
MGI ID: MGI:1857196
Synonyms: il4-, IL-4-
Gene: Il4  Location: Chr11:53503287-53509492 bp, - strand  Genetic Position: Chr11, 31.97 cM
Alliance: Il4tm1Nnt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:37196
Parent Cell Line:  BL/6-III (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance cassette was inserted into exon 3 of the gene. (J:36386)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il4 Mutation:  38 strains or lines available
References
Original:  J:37196 Metwali A, et al., The granulomatous response in murine Schistosomiasis mansoni does not switch to Th1 in IL-4-deficient C57BL/6 mice. J Immunol. 1996 Nov 15;157(10):4546-53
All:  73 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
02/20/2024
MGI 6.23
The Jackson Laboratory