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Targeted Allele Detail
Symbol: Dpp4tm1(DPP4)Vlcg
Name: dipeptidylpeptidase 4; targeted mutation 1, Velocigene
MGI ID: MGI:5788094
Gene: Dpp4  Location: Chr2:62160417-62242575 bp, - strand  Genetic Position: Chr2, 35.85 cM, cytoband C2-D
Alliance: Dpp4tm1(DPP4)Vlcg page
Germline Transmission:  Earliest citation of germline transmission: J:223728
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NTac)F1
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
Dpp4tm1(DPP4)Vlcg expresses 1 gene
Mutation detailsExons 2 through 26, including the 3'UTR, of the human genomic sequence (from BAC RP11-68L22) replaced 79 kb of the corresponding mouse sequence. (J:223728)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dpp4 Mutation:  51 strains or lines available
Original:  J:223728 Pascal KE, et al., Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8738-43
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory