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Targeted Allele Detail
Symbol: Gt(ROSA)26Sortm1(EYFP)Cos
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Frank Costantini
MGI ID: MGI:2449038
Synonyms: Gt(ROSA)26Sor-StopFlox-EYFP, LSLYFP, R26eYFP, R26::EYFP, R26ReYFP, R26ReYFP, R26R EYFP, R26R-EYFP, R26RYFP, R26RYFP, R26-stop-EYFP, R26Y, r26YFP, R26-YFP, R26YY, R-EYFP, ROSA26-EYFP, Rosa26-eYFPtg, ROSA26floxSTOPfloxYFP, ROSA26floxSTOP-YFP, ROSA26-LoxP-STOP-LoxP-EYFP, ROSA26-loxP-Stop-loxP-YF, ROSA26-lsl-EYFP, Rosa26LSL-YFP, Rosa26R(YFP), ROSA26R-YFP, Rosa26stopfloxYFP, Rosa26-Stopfl-YFP, ROSA26-stop-YFP reporter, Rosa26YFP, ROSA26-YFP, Rosa26-YFPfl, Rosa26-YFPst, Rosa26YFPStop, ROSAEYFP, ROSA-LSL-YFP, ROSA-YFP, Rosa-YFPf, RYR, YFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(EYFP)Cos page
Germline Transmission:  Earliest citation of germline transmission: J:80963
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
Mutation detailsA construct containing a floxed PGK-neo cassette and an enhanced yellow fluorescent protein (EYFP) gene was inserted into the Gt(ROSA)26Sor locus via homologous recombination. The floxed neo cassette contains a strong tpA stop sequence which prevents the transcription of EYFP. (J:80963)
Generation of Gt(ROSA)26Sortm1(EYFP)Cos or Gt(ROSA)26Sortm2(ECFP)Cos.
View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Gt(ROSA)26Sortm1(EYFP)Cos
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 12 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  968 strains or lines available
Original:  J:80963 Srinivas S, et al., Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1(1):4
All:  2282 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory