Pdgfra^tm8Sor
Targeted Allele Detail

Summary

• Symbol: Pdgfra^tm8Sor
• Name: platelet derived growth factor receptor, alpha polypeptide; targeted mutation 8, Philippe Soriano
• MGI ID: MGI:2449440
• Synonyms: PDGFRalpha^fl
• Gene: Pdgfra Location: Chr5:75312953-75358876 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Pdgfra^tm8Sor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81153
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Hypomorph)
• Mutation: Insertion
• Mutation details: A loxP site was introduced upstream of exon 1 and a PGK-neo-loxP cassette was introduced downstream of exon 4 via homologous recombination. (J:81153)

Expression

In Mice Carrying this Mutation:	15 assay results
In Structures Affected by this Mutation:	19 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pdgfra Mutation: 85 strains or lines available

References

• Original: J:81153 Tallquist MD, et al., Cell autonomous requirement for PDGFRalpha in populations of cranial and cardiac neural crest cells. Development. 2003 Feb;130(3):507-18
• All: 55 reference(s)