Relb^shep
Spontaneous Allele Detail

Summary

• Symbol: Relb^shep
• Name: avian reticuloendotheliosis viral (v-rel) oncogene related B; spontaneous hepatitis
• MGI ID: MGI:5002714
• Gene: Relb Location: Chr7:19340142-19363352 bp, - strand Genetic Position: Chr7, 9.93 cM
• Alliance: Relb^shep page

Reduced body size in Relb^shep/Relb^shep mice

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: BALB/cJ x A/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This spontaneous mutation has a G-to-T mutation at chromosome 7 position 19,612,646 (GRCm38) which causes a single amino acid change of glutamine to lysine at residue 331 (p.Q331K). (J:176116, J:222308)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Relb Mutation: 32 strains or lines available

References

• Original: J:171971 Harris B, et al., Spontaneous hepatitis: A new liver disease model exhibiting hepatitis maps to Chromosome 7. MGI Direct Data Submission. 2011
• All: 3 reference(s)