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Rag2tm2.1Desi
Targeted Allele Detail
Summary
Symbol: Rag2tm2.1Desi
Name: recombination activating gene 2; targeted mutation 2.1, Stephen Desiderio
MGI ID: MGI:4941316
Synonyms: Rag2WT*
Gene: Rag2  Location: Chr2:101455063-101462874 bp, + strand  Genetic Position: Chr2, 53.87 cM
Alliance: Rag2tm2.1Desi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168974
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Not Applicable)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette inserted upstream of the coding region was removed by cre-mediated recombination, leaving a single loxP site. (J:168974)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rag2 Mutation:  117 strains or lines available
References
Original:  J:168974 Zhang L, et al., Coupling of v(d)j recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis. Immunity. 2011 Feb 25;34(2):163-74
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory