Sox12^tm2.1Weg
Targeted Allele Detail

Summary

• Symbol: Sox12^tm2.1Weg
• Name: SRY (sex determining region Y)-box 12; targeted mutation 2.1, Michael Wegner
• MGI ID: MGI:5285296
• Gene: Sox12 Location: Chr2:152235531-152239966 bp, - strand Genetic Position: Chr2, 74.94 cM
• Alliance: Sox12^tm2.1Weg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175338
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed the coding region and neo cassette. The absence of transcript expression was confirmed by northern blot analysis. (J:175338)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox12 Mutation: 8 strains or lines available

References

• Original: J:175338 Bhattaram P, et al., Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun. 2010;1:9
• All: 8 reference(s)