Apoe^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Apoe^em1Gpt
• Name: apolipoprotein E; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6452938
• Synonyms: Apoe^em1Cd82
• Gene: Apoe Location: Chr7:19430034-19433113 bp, - strand Genetic Position: Chr7, 9.94 cM
• Alliance: Apoe^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 3 was targeted using CRISPR/Cas9 technology, resulting in an 82 bp deletion in that exon. (J:293395)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apoe Mutation: 163 strains or lines available

References

• Original: J:293395 Li H, et al., LncRNA MALAT1 modulates ox-LDL induced EndMT through the Wnt/beta-catenin signaling pathway. Lipids Health Dis. 2019 Mar 14;18(1):62
• All: 16 reference(s)