Myd88^M4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Myd88^M4Btlr
• Name: myeloid differentiation primary response gene 88; mutation 4, Bruce Beutler
• MGI ID: MGI:6113640
• Synonyms: Dani_alves
• Gene: Myd88 Location: Chr9:119165000-119169084 bp, - strand Genetic Position: Chr9, 71.33 cM
• Alliance: Myd88^M4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 119,337,823 (v38) on chromosome 9, or base pair 2,218 in the GenBank genomic region NC_000075. The mutation corresponds to residue 748 in the mRNA sequence NM_010851 within exon 4 of 6 total exons. The mutation results in a valine (V) to phenylalanine (F) substitution at position 223 (V223F) in the protein. (J:254917)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myd88 Mutation: 50 strains or lines available

References

• Original: J:254917 Ochoa CD, et al., Mutagenetix entry for Dani_alves. MGI Direct Data Submission. 2018
• All: 1 reference(s)