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Slc39a10tm1.1Tfk
Targeted Allele Detail
Summary
Symbol: Slc39a10tm1.1Tfk
Name: solute carrier family 39 (zinc transporter), member 10; targeted mutation 1.1, Toshiyuki Fukada
MGI ID: MGI:5642299
Synonyms: Zip10fl
Gene: Slc39a10  Location: Chr1:46846704-46932012 bp, - strand  Genetic Position: Chr1, 24.07 cM
Alliance: Slc39a10tm1.1Tfk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213932
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP-neomycin-loxP cassette was inserted upstream of exon 6 followed by a third loxP site in intron 8. The neomycin cassette was removed in the floxed allele. (J:213932, J:213935)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc39a10 Mutation:  49 strains or lines available
References
Original:  J:213932 Hojyo S, et al., Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11786-91
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory