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Tnfrsf13ctm2.1Mass
Targeted Allele Detail
Summary
Symbol: Tnfrsf13ctm2.1Mass
Name: tumor necrosis factor receptor superfamily, member 13c; targeted mutation 2.1, Marc Schmidt-Supprian
MGI ID: MGI:4949656
Synonyms: BAFF-RFL
Gene: Tnfrsf13c  Location: Chr15:82105944-82108570 bp, - strand  Genetic Position: Chr15, 38.56 cM
Alliance: Tnfrsf13ctm2.1Mass page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92732
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP was inserted upstream of exon 3. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette. (J:92732)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfrsf13c Mutation:  14 strains or lines available
References
Original:  J:92732 Sasaki Y, et al., TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J Immunol. 2004 Aug 15;173(4):2245-52
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory