Gpr18^tm1.1Cys
Targeted Allele Detail

Summary

• Symbol: Gpr18^tm1.1Cys
• Name: G protein-coupled receptor 18; targeted mutation 1.1, Jason G Cyster
• MGI ID: MGI:5708707
• Gene: Gpr18 Location: Chr14:122148846-122153300 bp, - strand Genetic Position: Chr14, 65.86 cM
• Alliance: Gpr18^tm1.1Cys page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219661
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1.4kb region including the single exon was floxed and an FRT flanked neo gene was inserted via homologous recombination. Cre mediated recombination removed the single exon. (J:219661)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr18 Mutation: 19 strains or lines available

References

• Original: J:219661 Wang X, et al., GPR18 is required for a normal CD8alphaalpha intestinal intraepithelial lymphocyte compartment. J Exp Med. 2014 Nov 17;211(12):2351-9
• All: 5 reference(s)