Gzmmtm1(cre)Mjs
Targeted Allele Detail
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Symbol: |
Gzmmtm1(cre)Mjs |
Name: |
granzyme M (lymphocyte met-ase 1); targeted mutation 1, Mark J Smyth |
MGI ID: |
MGI:3665444 |
Synonyms: |
GrzM-, GrzM cre |
Gene: |
Gzmm Location: Chr10:79524854-79531095 bp, + strand Genetic Position: Chr10, 39.72 cM, cytoband C
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Alliance: |
Gzmmtm1(cre)Mjs page
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Germline Transmission: |
Earliest citation of germline transmission:
J:113213
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Gzmmtm1(cre)Mjs expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Gzmm (MGI:99549) |
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Mutation details: Cre recombinase cDNA was inserted directly upstream of the ATG in exon 1. An frt-flanked neo was included in the vector and was removed in vivo. RT-PCR demonstrated expression of cre in the mutant mice and the absence of full-length Gzmm transcript in mutants.
(J:113213)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Gzmm
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gzmm Mutation: |
7 strains or lines available
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Original: |
J:113213 Pao LI, et al., Functional analysis of granzyme M and its role in immunity to infection. J Immunol. 2005 Sep 1;175(5):3235-43 |
All: |
5 reference(s) |
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