Imm1^NZW
QTL Variant Detail

Summary

• QTL variant: Imm1^NZW
• Name: IgM serum level modifier 1; NZW
• MGI ID: MGI:2155947
• QTL: Imm1 Location: unknown Genetic Position: Chr4, Syntenic

Variant origin

• Strain of Specimen: NZW

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers decreased serum IgM levels compared to NZB. (J:26266)
• Inheritance: Dominant

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:26266

The authors show the following order of loci in mouse Chromosome 4: The number between the loci represents the genetic distance based on percent recombination in crosses involving NZW and NZB mice: Imm1- 38.6 - Mup1 - 15.6 - b - 28.7 - Imh1.

References

• Original: J:26266 Hirose S, et al., Genetic regulation of hypergammaglobulinaemia and the correlation to autoimmune traits in (NZB X NZW) F1 hybrid. Clin Exp Immunol. 1984 Dec;58(3):694-702
• All: 1 reference(s)