Tcf3^tm5.1Cmu
Targeted Allele Detail

Summary

• Symbol: Tcf3^tm5.1Cmu
• Name: transcription factor 3; targeted mutation 5.1, Cornelis Murre
• MGI ID: MGI:5424883
• Synonyms: E2A^S528A, Tcfe2a^S528A
• Gene: Tcf3 Location: Chr10:80245348-80269481 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Tcf3^tm5.1Cmu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183781
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Single point mutation
• Mutation details: The triplet encoding the serine residue (AGT) 528 was replaced by a triplet encoding an alanine amino acid (GCT). (J:183781)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcf3 Mutation: 39 strains or lines available

References

• Original: J:183781 Teachenor R, et al., Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47. Mol Cell Biol. 2012 May;32(9):1671-82
• All: 1 reference(s)