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Rbm3tm1Ttg
Targeted Allele Detail
Summary
Symbol: Rbm3tm1Ttg
Name: RNA binding motif (RNP1, RRM) protein 3; targeted mutation 1, Tadatsugu Taniguchi
MGI ID: MGI:5285686
Gene: Rbm3  Location: ChrX:8005214-8012119 bp, - strand  Genetic Position: ChrX, 3.68 cM
Alliance: Rbm3tm1Ttg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174947
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3 through 6 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:174947)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rbm3 Mutation:  15 strains or lines available
References
Original:  J:174947 Matsuda A, et al., Generation of mice deficient in RNA-binding motif protein 3 (RBM3) and characterization of its role in innate immune responses and cell growth. Biochem Biophys Res Commun. 2011 Jul 22;411(1):7-13
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/24/2024
MGI 6.24
The Jackson Laboratory