Tor1b^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tor1b^em1(IMPC)Mbp
• Name: torsin family 1, member B; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7507212
• Gene: Tor1b Location: Chr2:30842971-30849027 bp, + strand Genetic Position: Chr2, 21.76 cM, cytoband B
• Alliance: Tor1b^em1(IMPC)Mbp page
• IMPC: Tor1b gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences CCGCGGGAGACACACACGGC and TTGCCCAGTTTATGGCATGT that targeted exon(s) ENSMUSE00000772759.2 ENSMUSE00000662810.2. This resulted in deletion(s) of 2 bp (location: Chr2:30843226-30843227; GRCm39), 317 bp (location: Chr2:30844059-30844375; GRCm39), and 731 bp (location: Chr2:30843324-30844054; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tor1b Mutation: 18 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)