Card11^M7Btlr
Chemically induced Allele Detail

Summary

• Symbol: Card11^M7Btlr
• Name: caspase recruitment domain family, member 11; mutation 7, Bruce Beutler
• MGI ID: MGI:6304449
• Synonyms: Caravaggio
• Gene: Card11 Location: Chr5:140858745-140986337 bp, - strand Genetic Position: Chr5, 79.42 cM
• Alliance: Card11^M7Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 140,913,309 (v38) on chromosome 5, or base pair 87,288 in the GenBank genomic region NC_000071 encoding Card11. The mutation corresponds to residue 430 in the mRNA sequence NM_175362 within exon 3 of 25 total exons. The mutation results in an isoleucine to phenylalanine substitution at position 37 (I37F) in the CARMA1 protein. (J:274762)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Card11 Mutation: 58 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4190

References

• Original: J:274762 Zhong X, et al., Mutagenetix entry for Caravaggio. MGI Direct Data Submission. 2019
• All: 1 reference(s)