Pknox1Gt(OST71835)Lex
Gene trapped Allele Detail
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Symbol: |
Pknox1Gt(OST71835)Lex |
Name: |
Pbx/knotted 1 homeobox; gene trap OST71835, Lexicon Genetics |
MGI ID: |
MGI:3530910 |
Synonyms: |
Pknox1Gt(neo)628Lex, Prep1i |
Gene: |
Pknox1 Location: Chr17:31783708-31826667 bp, + strand Genetic Position: Chr17, 16.78 cM, cytoband B-C
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Alliance: |
Pknox1Gt(OST71835)Lex page
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Mutant Cell Line: |
OST71835 |
Germline Transmission: |
Earliest citation of germline transmission:
J:103485
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Parent Cell Line: |
Lex-1 (ES Cell)
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Strain of Origin: |
129S5/SvEvBrd
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Project Collection: |
Lexicon
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Allele Type: |
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Gene trapped (Hypomorph) |
Mutation: |
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Insertion of gene trap vector
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Mutation details: The clone used for gene trapping was isolated from a library of embryonic stem cells randomly targeted with the retroviral vector VICTR45 using an enhancer trap strategy. Retroviral insertion occurred at nucleotide 849 of intron 1 located within the 5' untranslated region (2.8 kb from the ATG). RT-PCR analysis revealed that transcript was absent in most homozygous mice. However, in some homozygotes a low level of protein (about 5-10% of wild-type) is detected.
(J:103485, J:103769, J:111418)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
172 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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View phenotypes and curated references for all genotypes (concatenated display).
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See also, data as provided by Lexicon Genetics, Inc.
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Original: |
J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005; |
All: |
21 reference(s) |
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