Pla2g7^tm1.1Mcap
Targeted Allele Detail

Summary

• Symbol: Pla2g7^tm1.1Mcap
• Name: phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma); targeted mutation 1.1, Michael Caplan
• MGI ID: MGI:5707934
• Gene: Pla2g7 Location: Chr17:43878989-43923092 bp, + strand Genetic Position: Chr17, 19.74 cM, cytoband C
• Alliance: Pla2g7^tm1.1Mcap page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228564
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 3-4 were replaced with a self-excising selection cassette via homologous recombination. (J:228564)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pla2g7 Mutation: 17 strains or lines available

References

• Original: J:228564 Lu J, et al., Dual roles of endogenous platelet-activating factor acetylhydrolase in a murine model of necrotizing enterocolitis. Pediatr Res. 2010 Sep;68(3):225-30
• All: 3 reference(s)