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Atg3tm1.1Ywh
Targeted Allele Detail
Summary
Symbol: Atg3tm1.1Ywh
Name: autophagy related 3; targeted mutation 1.1, You-Wen He
MGI ID: MGI:5009305
Synonyms: Atg3f
Gene: Atg3  Location: Chr16:44979192-45008901 bp, + strand  Genetic Position: Chr16, 29.45 cM, cytoband B5
Alliance: Atg3tm1.1Ywh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:172749
Parent Cell Line:  EF1 (ES Cell)
Strain of Origin:  129S/SvEv x C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 8. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 10. Flp-mediated recombination removed the neo cassette and left exons 8 through 10 floxed. (J:172749)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atg3 Mutation:  19 strains or lines available
References
Original:  J:172749 Jia W, et al., Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy. J Immunol. 2011 May 1;186(9):5313-22
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory