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Ebf1m6Btlr
Chemically induced Allele Detail
Summary
Symbol: Ebf1m6Btlr
Name: early B cell factor 1; mutation 6, Bruce Beutler
MGI ID: MGI:6286045
Synonyms: ebby
Gene: Ebf1  Location: Chr11:44508144-44898918 bp, + strand  Genetic Position: Chr11, 26.45 cM
Alliance: Ebf1m6Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced G to T transversion at base pair 44,883,814 (v38) on chromosome 11, or base pair 251,075 in the GenBank genomic region NC_000077. The mutation corresponds to residue 716 in the mRNA sequence NM_001290709 within exon 8 of 16 total exons. The mutation results in a valine to phenylalanine substitution at position 213 (V213F) in the EBF1 protein. (J:272842)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf1 Mutation:  73 strains or lines available
Notes
https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4112
References
Original:  J:272842 Zhong X, et al., Mutagenetix entry for ebby. MGI Direct Data Submission. 2019;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory