Tg(Tek-Procr)1Cte
Transgene Detail

Summary

• Symbol: Tg(Tek-Procr)1Cte
• Name: transgene insertion 1, Charles T Esmon
• MGI ID: MGI:3703326
• Synonyms: Tek-Procr, Tie2-EPCR
• Transgene: Tg(Tek-Procr)1Cte Location: unknown
• Alliance: Tg(Tek-Procr)1Cte page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tek-Procr)1Cte expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Procr (MGI:104596)

• Mutation details: The murine EPCR transgene, consisting of 750 bp murine Procr cDNA and 400 bp SV40 polyA signal sequence was ligated to the murine 2.1 kb Tek promoter. The murine Tek enhancer fragment, extending from a Nae I site of exon 1 approximately 10 kb into the first intron was ligated downstream of the SV40 polyA sequence. (J:119637)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:119637 Li W, et al., Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin. J Thromb Haemost. 2005 Jul;3(7):1351-9
• All: 7 reference(s)